ChEBI subsumes and replaces the Chemical Ontology first
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developed by Michael Ashburner & Pankaj Jaiswal.
An EC 5.4.99.* (intramolecular transferase transferring other groups) inhibitor that interferes with the action of lanosterol synthase (EC 5.4.99.7).
substance with EC 5.4.99.7 (lanosterol synthase) inhibitor role
An EC 5.4.* (intramolecular transferase) inhibitor that interferes with the activity of any intramolecular transferase transferring other groups (EC 5.4.99.*).
EC 5.4.99.* (intramolecular transferase transferring other groups) inhibitors
inhibitor of intramolecular transferase transferring other groups
inhibitors of intramolecular transferase transferring other groups
intramolecular transferase transferring other groups inhibitor
intramolecular transferase transferring other groups inhibitors
substance with EC 5.4.99.* (intramolecular transferase transferring other groups) inhibitor role
An EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor that interferes with the action of hypoxia-inducible factor-proline dioxygenase (EC 1.14.11.29).
EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitors
hypoxia-inducible factor-L-proline, 2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) inhibitor
hypoxia-inducible factor-L-proline, 2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) inhibitors
substance with EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor role
An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of (R)-3-amino-2-methylpropionate--pyruvate transaminase (EC 2.6.1.40).
(R)-3-amino-2-methylpropanoate:pyruvate aminotransferase inhibitor
(R)-3-amino-2-methylpropanoate:pyruvate aminotransferase inhibitors
(R)-3-amino-2-methylpropionate transaminase inhibitor
(R)-3-amino-2-methylpropionate transaminase inhibitors
(R)-3-amino-2-methylpropionate--pyruvate aminotransferase inhibitor
(R)-3-amino-2-methylpropionate--pyruvate aminotransferase inhibitors
D-3-aminoisobutyrate--pyruvate aminotransferase inhibitor
D-3-aminoisobutyrate--pyruvate aminotransferase inhibitors
D-3-aminoisobutyrate--pyruvate transaminase inhibitor
D-3-aminoisobutyrate--pyruvate transaminase inhibitors
D-3-aminoisobutyrate-pyruvate aminotransferase inhibitor
D-3-aminoisobutyrate-pyruvate aminotransferase inhibitors
D-3-aminoisobutyrate-pyruvate transaminase inhibitor
D-3-aminoisobutyrate-pyruvate transaminase inhibitors
D-beta-aminoisobutyrate:pyruvate aminotransferase inhibitor
D-beta-aminoisobutyrate:pyruvate aminotransferase inhibitors
EC 2.6.1.40 [(R)-3-amino-2-methylpropionate--pyruvate transaminase] inhibitors
beta-aminoisobutyrate--pyruvate aminotransferase inhibitor
beta-aminoisobutyrate--pyruvate aminotransferase inhibitors
beta-aminoisobutyrate--pyruvate transaminase inhibitor
beta-aminoisobutyrate--pyruvate transaminase inhibitors
beta-aminoisobutyrate-pyruvate aminotransferase inhibitor
beta-aminoisobutyrate-pyruvate aminotransferase inhibitors
substance with EC 2.6.1.40 [(R)-3-amino-2-methylpropionate--pyruvate transaminase] inhibitor role
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of histamine N-methyltransferase (EC 2.1.1.8).
EC 2.1.1.8 (histamine N-methyltransferase) inhibitors
S-adenosyl-L-methionine:histamine N-tele-methyltransferase inhibitor
S-adenosyl-L-methionine:histamine N-tele-methyltransferase inhibitors
S-adenosylmethionine-histamine N-methyltransferase inhibitor
S-adenosylmethionine-histamine N-methyltransferase inhibitors
histamine 1-methyltransferase inhibitors
substance with EC 2.1.1.8 (histamine N-methyltransferase) inhibitor role
An antagonist that interferes with the action of the calcium-binding messenger protein calmodulin.
substance with calmodulin antagonist role
An antagonist that binds to and deactivates IP3 receptors.
D-myo-inositol 1,4,5-trisphosphate receptor antagonist
D-myo-inositol 1,4,5-trisphosphate receptor antagonists
inositol trisphosphate receptor antagonist
inositol trisphosphate receptor antagonists
substance with IP3 receptor antagonist role
substance with adenosine A2B receptor agonist role
A substance that activates any of the Wnt signalling pathway, a group of signal transduction pathways made of proteins that pass signals from outside of a cell through cell surface receptors to the inside of the cell.
substance with Wnt signalling activator role
An agonist that binds to and activates formyl peptide receptors.
substance with formyl peptide receptor agonist role
An EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of lysine-specific histone demethylase 1A (EC 1.14.99.66).
EC 1.14.99.66 (lysine-specific histone demethylase 1A) inhibitors
[histone H3]-dimethyl-L-lysine(4)FAD-dependent demethylase 1A inhibitor
[histone H3]-dimethyl-L-lysine(4)FAD-dependent demethylase 1A inhibitors
amine oxidase (flavin containing) domain 2 inhibitor
amine oxidase (flavin containing) domain 2 inhibitors
lysine (K)-specific demethylase 1A inhibitor
lysine (K)-specific demethylase 1A inhibitors
lysine-specific demethylase 1A inhibitor
lysine-specific demethylase 1A inhibitors
lysine-specific histone demethylase 1A inhibitor
lysine-specific histone demethylase 1A inhibitors
substance with EC 1.14.99.66 (lysine-specific histone demethylase 1A) inhibitor role
Any compound that inhibits one or more steps in the pathway leading to the synthesis of hyaluronic acid.
substance with hyaluronic acid synthesis inhibitor role
Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium.
substance with Mycoplasma genitalium metabolite role
Any compound that inhibits the biosynthesis of teichoic acid.
substance with teichoic acid biosynthesis inhibitor role
A DNA polymerase inhibitor that interferes with the action of a DNA-directed DNA polymerase (EC 2.7.7.7).
DNA nucleotidyltransferase (DNA-directed) inhibitor
DNA nucleotidyltransferase (DNA-directed) inhibitors
DNA-directed DNA polymerase (EC 2.7.7.7) inhibitor
DNA-directed DNA polymerase (EC 2.7.7.7) inhibitors
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitors
deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) inhibitor
deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) inhibitors
deoxyribonucleate nucleotidyltransferase inhibitor
deoxyribonucleate nucleotidyltransferase inhibitors
deoxyribonucleic acid duplicase inhibitor
deoxyribonucleic acid duplicase inhibitors
deoxyribonucleic acid polymerase inhibitor
deoxyribonucleic acid polymerase inhibitors
deoxyribonucleic polymerase I inhibitors
substance with EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor role
Any EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of elongation factor 2 kinase (EC 2.7.11.20).
ATP:[elongation factor 2] phosphotransferase inhibitor
ATP:[elongation factor 2] phosphotransferase inhibitors
EC 2.7.11.20 (elongation factor 2 kinase) inhibitors
calmodulin-dependent protein kinase III inhibitor
calmodulin-dependent protein kinase III inhibitors
elongation factor 2 kinase (EC 2.7.11.20) inhibitor
elongation factor 2 kinase (EC 2.7.11.20) inhibitors
substance with EC 2.7.11.20 (elongation factor 2 kinase) inhibitor role
A EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of channel-conductance-controlling ATPase (EC 3.6.3.49, also known as cystic fibrosis conductance regulator, CFCR).
ATP phosphohydrolase (channel-conductance-controlling) inhibitor
ATP phosphohydrolase (channel-conductance-controlling) inhibitors
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitors
channel-conductance-controlling ATPase (EC 3.6.3.49) inhibitor
channel-conductance-controlling ATPase (EC 3.6.3.49) inhibitors
channel-conductance-controlling ATPase inhibitor
channel-conductance-controlling ATPase inhibitors
cystic fibrosis conductance regulator inhibitor
cystic fibrosis conductance regulator inhibitors
cystic fibrosis transmembrane conductance regulator inhibitor
cystic fibrosis transmembrane conductance regulator inhibitors
cystic-fibrosis membrane-conductance-regulating protein inhibitor
cystic-fibrosis membrane-conductance-regulating protein inhibitors
substance with EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor role
An antagonist that binds to and deactivates the dopamine receptor D2, the main receptor for all antipsychotic drugs.
substance with dopamine receptor D2 antagonist role
An inhibitor that interferes with RUNX1 (runt-related transcription factor 1), a transcription factor protein that regulates the differentiation of haematopoietic stem cells into mature blood cells.
acute myeloid leukemia 1 protein inhibitor
acute myeloid leukemia 1 protein inhibitors
core-binding factor subunit alpha-2 inhibitor
core-binding factor subunit alpha-2 inhibitors
core-binding factor subunit alpha2 inhibitor
core-binding factor subunit alpha2 inhibitors
runt-related transcription factor 1 inhibitor
runt-related transcription factor 1 inhibitors
An antagonist that binds to and deactivates melatonin receptors.
substance with melatonin receptor antagonist role
An inhibitor of gene expression of human immunodeficiency virus type 1 (HIV-1) at the transcriptional level through interference with Tat-mediated transactivation.
HIV-1 trans-activator of transcription antagonist
HIV-1 trans-activator of transcription antagonists
human immunodeficiency virus type 1 Tat antagonist
human immunodeficiency virus type 1 Tat antagonists
human immunodeficiency virus type 1 Tat inhibitor
human immunodeficiency virus type 1 Tat inhibitors
human immunodeficiency virus type 1 trans-activator of transcription antagonist
human immunodeficiency virus type 1 trans-activator of transcription antagonists
Any EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of a Ca(2+)/calmodulin-dependent protein kinase (EC 2.7.11.17).
ATP:caldesmon O-phosphotransferase inhibitor
ATP:caldesmon O-phosphotransferase inhibitors
ATP:protein phosphotransferase ((2+)/calmodulin-dependent) inhibitor
ATP:protein phosphotransferase ((2+)/calmodulin-dependent) inhibitors
Ca(2+)/calmodulin-dependent microtubule-associated protein 2 kinase inhibitor
Ca(2+)/calmodulin-dependent microtubule-associated protein 2 kinase inhibitors
Ca(2+)/calmodulin-dependent protein kinase (EC 2.7.11.17) inhibitor
Ca(2+)/calmodulin-dependent protein kinase (EC 2.7.11.17) inhibitors
Ca(2+)/calmodulin-dependent protein kinase 1 inhibitor
Ca(2+)/calmodulin-dependent protein kinase 1 inhibitors
Ca(2+)/calmodulin-dependent protein kinase II inhibitor
Ca(2+)/calmodulin-dependent protein kinase II inhibitors
Ca(2+)/calmodulin-dependent protein kinase IV inhibitor
Ca(2+)/calmodulin-dependent protein kinase IV inhibitors
Ca(2+)/calmodulin-dependent protein kinase inhibitor
Ca(2+)/calmodulin-dependent protein kinase inhibitors
Ca(2+)/calmodulin-dependent protein kinase kinase beta inhibitor
Ca(2+)/calmodulin-dependent protein kinase kinase beta inhibitors
Ca(2+)/calmodulin-dependent protein kinase kinase inhibitor
Ca(2+)/calmodulin-dependent protein kinase kinase inhibitors
CaM-regulated serine/threonine kinase inhibitor
CaM-regulated serine/threonine kinase inhibitors
EC 2.7.11.17 (Ca(2+)/calmodulin-dependent protein kinase) inhibitors
caldesmon kinase (phosphorylating) inhibitor
caldesmon kinase (phosphorylating) inhibitors
calmodulin-dependent kinase II inhibitor
calmodulin-dependent kinase II inhibitors
microtubule-associated protein 2 kinase inhibitor
microtubule-associated protein 2 kinase inhibitors
substance with EC 2.7.11.17 (Ca(2+)/calmodulin-dependent protein kinase) inhibitor role
A dopamine agonist that binds to and activates the dopamine receptor D1.
substance with dopamine receptor D1 agonist role
An agonist that enhances the action of smoothened (SMO) receptor.
substance with SMO receptor agonist role
An EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor that interferes with the action of gamma-butyrobetaine dioxygenase (EC 1.14.11.1).
4-trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) inhibitor
4-trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) inhibitors
EC 1.14.11.1 (gamma-butyrobetaine dioxygenase) inhibitors
alpha-butyrobetaine hydroxylase inhibitor
alpha-butyrobetaine hydroxylase inhibitors
gamma-butyrobetaine hydroxylase inhibitor
gamma-butyrobetaine hydroxylase inhibitors
substance with EC 1.14.11.1 (gamma-butyrobetaine dioxygenase) inhibitor role
A molecular entity that can undergo reduction by the gain of hydrogen atom(s).
An EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor that interferes with the action of tryptophan 2,3-dioxygenase (EC 1.13.11.11).
EC 1.13.11.11 (tryptophan 2,3-dioxygenase) inhibitors
L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) inhibitor
L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) inhibitors
L-tryptophan:oxygen 2,3-oxidoreductase (ring-opening) inhibitor
L-tryptophan:oxygen 2,3-oxidoreductase (ring-opening) inhibitors
tryptophan 2,3-dioxygenase (EC 1.13.11.11) inhibitor
tryptophan 2,3-dioxygenase (EC 1.13.11.11) inhibitors
substance with EC 1.13.11.11 (tryptophan 2,3-dioxygenase) inhibitor role
A compound used with herbicides that reduces the effect of the herbicide on crop plants or otherwise improves the selectivity of the herbicide for weed species over the crop plant.
An EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor that interferes with the action of procollagen-proline dioxygenase (EC 1.14.11.2).
EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitors
hydroxylase, collagen proline inhibitors
procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) inhibitor
procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) inhibitors
procollagen-proline 4-dioxygenase inhibitor
procollagen-proline 4-dioxygenase inhibitors
procollagen-proline dioxygenase (EC 1.14.11.2) inhibitor
procollagen-proline dioxygenase (EC 1.14.11.2) inhibitors
procollagen-proline dioxygenase inhibitor
procollagen-proline dioxygenase inhibitors
procollagen-proline,2-oxoglutarate-4-dioxygenase inhibitor
procollagen-proline,2-oxoglutarate-4-dioxygenase inhibitors
proline protocollagen hydroxylase inhibitor
proline protocollagen hydroxylase inhibitors
proline, 2-oxoglutarate dioxygenase inhibitor
proline, 2-oxoglutarate dioxygenase inhibitors
proline,2-oxoglutarate 4-dioxygenase inhibitor
proline,2-oxoglutarate 4-dioxygenase inhibitors
prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating inhibitor
prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating inhibitors
prolylprotocollagen dioxygenase inhibitor
prolylprotocollagen dioxygenase inhibitors
prolylprotocollagen hydroxylase inhibitor
prolylprotocollagen hydroxylase inhibitors
protocollagen proline 4-hydroxylase inhibitor
protocollagen proline 4-hydroxylase inhibitors
protocollagen proline dioxygenase inhibitor
protocollagen proline dioxygenase inhibitors
protocollagen proline hydroxylase inhibitor
protocollagen proline hydroxylase inhibitors
protocollagen prolyl hydroxylase inhibitor
protocollagen prolyl hydroxylase inhibitors
substance with EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor role
An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of beta-galactosidase (EC 3.2.1.23).
EC 3.2.1.23 (beta-galactosidase) inhibitors
beta-D-galactoside galactohydrolase inhibitor
beta-D-galactoside galactohydrolase inhibitors
exo-(1->4)-beta-D-galactanase inhibitors
substance with EC 3.2.1.23 (beta-galactosidase) inhibitor role
An inhibitor of transient receptor potential cation channel subfamily M member 4.
Transient receptor potential cation channel subfamily M member 4 inhibitor
Transient receptor potential cation channel subfamily M member 4 inhibitors
substance with TRPM4 channel inhibitor role
An antigen that is found in more than one species.
A reagent that lightens or whitens a substrate through chemical reaction. Bleaching reactions usually involve oxidative or reductive processes that degrade colour systems. Bleaching can occur by destroying one or more of the double bonds in the conjugated chain, by cleaving the conjugated chain, or by oxidation of one of the other moieties in the conjugated chain. Their reactivity results in many bleaches having strong bactericidal, disinfecting, and sterilising properties.
Any EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme acting on GTP that is involved in cellular and subcellular movement (EC 3.6.5.*).
EC 3.6.5.* (hydrolases acting on GTP; involved in cellular and subcellular movement) inhibitors
substance with EC 3.6.5.* (hydrolases acting on GTP; involved in cellular and subcellular movement) inhibitor role
An EC 3.6.5.* (hydrolases acting on GTP; involved in cellular and subcellular movement) inhibitor that interferes with the action of dynamin GTPase (EC 3.6.5.5).
GTP phosphohydrolase (vesicle-releasing) inhibitor
GTP phosphohydrolase (vesicle-releasing) inhibitors
substance with EC 3.6.5.5 (dynamin GTPase) inhibitor role
An agonist that binds to and activates farnesoid X receptors
substance with farnesoid X receptor agonist role
A drug that makes increases the sensitivity of tumour cells to radiation therapy.
substance with radiosensitizing agent role
An inverse agonist that binds to the same receptor as a 5-hydroxytryptamine 2A receptor agonist, but which induces a pharmacological response opposite to that agonist.
5-hydroxytryptamine (2A) receptor inverse agonist
5-hydroxytryptamine (2A) receptor inverse agonists
5-hydroxytryptamine 2A receptor inverse agonists
substance with 5-hydroxytryptamine 2A receptor inverse agonist role
Any inhibitor of B-cell lymphoma 2 protein.
substance with B-cell lymphoma 2 inhibitor role
Any antagonist of lymphocyte function-associated antigen-1
lymphocyte function-associated antigen-1 antagonists
substance with lymphocyte function-associated antigen-1 antagonist role
A plant growth regulator that produces male sterility in plants by preventing pollen development, pollen shed, or pollen viability. This makes the plant adaptable to hybridization without the need for laborious hand pollination.
substance with chemical hybridisation agent role
A compound that inhibits the oxidation of any fatty acid.
substance with fatty acid oxidation inhibitor role
A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of glucuronosyltransferase (EC 2.4.1.17).
1-naphthol glucuronyltransferase inhibitor
1-naphthol glucuronyltransferase inhibitors
1-naphthol-UDP-glucuronosyltransferase inhibitor
1-naphthol-UDP-glucuronosyltransferase inhibitors
17beta-hydroxysteroid UDP-glucuronosyltransferase inhibitor
17beta-hydroxysteroid UDP-glucuronosyltransferase inhibitors
3alpha-hydroxysteroid UDP-glucuronosyltransferase inhibitor
3alpha-hydroxysteroid UDP-glucuronosyltransferase inhibitors
4-hydroxybiphenyl UDP-glucuronosyltransferase inhibitor
4-hydroxybiphenyl UDP-glucuronosyltransferase inhibitors
EC 2.4.1.17 (glucuronosyltransferase) inhibitors
UDP glucuronic acid transferase inhibitors
UDP-alpha-D-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific; conformation-inverting) inhibitor
UDP-alpha-D-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific; conformation-inverting) inhibitors
UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) inhibitor
UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) inhibitors
uridine 5'-diphosphoglucuronyltransferase inhibitor
uridine 5'-diphosphoglucuronyltransferase inhibitors
uridine diphosphate glucuronyltransferase inhibitor
uridine diphosphate glucuronyltransferase inhibitors
uridine diphosphoglucuronosyltransferase inhibitor
uridine diphosphoglucuronosyltransferase inhibitors
uridine diphosphoglucuronyltransferase inhibitor
uridine diphosphoglucuronyltransferase inhibitors
substance with EC 2.4.1.17 (glucuronosyltransferase) inhibitor role
An antagonist that binds to and deactivates neuropeptide Y receptors.
substance with neuropeptide Y receptor antagonist role
Any protein kinase inhibitor that interferes with the action of salt-inducible kinase 2.
serine/threonine-protein kinase SIK2 inhibitor
substance with salt-inducible kinase 2 inhibitor role
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of deoxyhypusine synthase (EC 2.5.1.46).
(4-aminobutyl)lysine synthase inhibitors
EC 2.5.1.46 (deoxyhypusine synthase) inhibitors
[eIF-5A]-deoxyhypusine synthase inhibitor
[eIF-5A]-deoxyhypusine synthase inhibitors
[eIF5A-precursor]-lysine:spermidine 4-aminobutyltransferase (propane-1,3-diamine-forming) inhibitor
[eIF5A-precursor]-lysine:spermidine 4-aminobutyltransferase (propane-1,3-diamine-forming) inhibitors
spermidine:eIF5A-lysine 4-aminobutyltransferase (propane-1,3-diamine-forming) inhibitor
spermidine:eIF5A-lysine 4-aminobutyltransferase (propane-1,3-diamine-forming) inhibitors
substance with EC 2.5.1.46 (deoxyhypusine synthase) inhibitor role
An activator that activates the hypoxia inducible factor (HIF) pathway.
hypoxia-inducible factor pathway activators
substance with hypoxia-inducible factor pathway activator role
substance with EC 1.15.1.1 (superoxide dismutase) inhibitor role
Any compound that inhibits the biosynthesis of any lipopolysaccharide.
lipopolysaccharide biosynthesis inhibitors
substance with lipopolysaccharide biosynthesis inhibitor role
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of UDP-3-O-acyl-N-acetylglucosamine deacetylase (EC 3.5.1.108).
EC 3.5.1.108 (UDP-3-O-acyl-N-acetylglucosamine deacetylase) inhibitors
UDP-(3-O-(R-3-hydroxymyristoyl))-N-acetylglucosamine deacetylase inhibitor
UDP-(3-O-(R-3-hydroxymyristoyl))-N-acetylglucosamine deacetylase inhibitors
UDP-(3-O-acyl)-N-acetylglucosamine deacetylase inhibitor
UDP-(3-O-acyl)-N-acetylglucosamine deacetylase inhibitors
UDP-3-O-((R)-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase inhibitor
UDP-3-O-((R)-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase inhibitors
UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase inhibitor
UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase inhibitors
UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-alpha-D-glucosamine amidohydrolase inhibitor
UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-alpha-D-glucosamine amidohydrolase inhibitors
UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetylglucosamine amidohydrolase inhibitor
UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetylglucosamine amidohydrolase inhibitors
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase inhibitor
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase inhibitors
UDP-3-O-acyl-GlcNAc deacetylase inhibitor
UDP-3-O-acyl-GlcNAc deacetylase inhibitors
substance with EC 3.5.1.108 (UDP-3-O-acyl-N-acetylglucosamine deacetylase) inhibitor role
A role borne by a molecule that acts to counteract or neutralise the deleterious effects of barbiturates.
substance with antidote to barbiturate poisoning role
An antagonist that acts at the platelet-activating factor receptor.
platelet-activating factor receptor antagonists
substance with platelet-activating factor receptor antagonist role
An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of dihydrolipoyl dehydrogenase (EC 1.8.1.4).
E3 component of alpha-ketoacid dehydrogenase complexes inhibitor
E3 component of alpha-ketoacid dehydrogenase complexes inhibitors
EC 1.8.1.4 (dihydrolipoyl dehydrogenase) inhibitors
dihydrolipoamide dehydrogenase inhibitor
dihydrolipoamide dehydrogenase inhibitors
dihydrolipoamide:NAD(+) oxidoreductase inhibitor
dihydrolipoamide:NAD(+) oxidoreductase inhibitors
dihydrothioctic dehydrogenase inhibitors
glycine-cleavage system L-protein inhibitor
glycine-cleavage system L-protein inhibitors
lipoamide dehydrogenase (NADH) inhibitor
lipoamide dehydrogenase (NADH) inhibitors
lipoamide oxidoreductase (NADH) inhibitor
lipoamide oxidoreductase (NADH) inhibitors
protein-6-N-(dihydrolipoyl)lysine:NAD(+) oxidoreductase inhibitor
protein-6-N-(dihydrolipoyl)lysine:NAD(+) oxidoreductase inhibitors
protein-N(6)-(dihydrolipoyl)lysine:NAD(+) oxidoreductase inhibitor
protein-N(6)-(dihydrolipoyl)lysine:NAD(+) oxidoreductase inhibitors
substance with EC 1.8.1.4 (dihydrolipoyl dehydrogenase) inhibitor role
An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of hypoxanthine phosphoribosyltransferase (EC 2.4.2.8).
6-hydroxypurine phosphoribosyltransferase inhibitor
6-mercaptopurine phosphoribosyltransferase inhibitor
EC 2.4.2.8 (hypoxanthine phosphoribosyltransferase) inhibitors
IMP:diphosphate phospho-D-ribosyltransferase inhibitor
guanine phosphoribosyltransferase inhibitor
guanine-hypoxanthine phosphoribosyltransferase inhibitor
guanosine 5'-phosphate pyrophosphorylase inhibitor
guanosine phosphoribosyltransferase inhibitor
hypoxanthine phosphoribosyltransferase (EC 2.4.2.8) inhibitor
hypoxanthine phosphoribosyltransferase (EC 2.4.2.8) inhibitors
hypoxanthine phosphoribosyltransferase inhibitor
hypoxanthine phosphoribosyltransferase inhibitors
hypoxanthine-guanine phosphoribosyltransferase inhibitor
inosine 5'-phosphate pyrophosphorylas inhibitore
inosinic acid pyrophosphorylase inhibitor
purine-6-thiol phosphoribosyltransferase inhibitor
substance with EC 2.4.2.8 (hypoxanthine phosphoribosyltransferase) inhibitor role
An inhibitor of peroxidases (EC 1.11.1.*) that inhibits the action of peroxidase (EC 1.11.1.7).
Arthromyces ramosus peroxidase inhibitor
Arthromyces ramosus peroxidase inhibitors
phenolic donor:hydrogen-peroxide oxidoreductase inhibitor
phenolic donor:hydrogen-peroxide oxidoreductase inhibitors
substance with EC 1.11.1.7 (peroxidase) inhibitor role
An antagonist that acts at the liver receptor homologue-1.
nuclear receptor subfamily 5 group A member 2 antagonist
nuclear receptor subfamily 5 group A member 2 antagonists
A prodrug that, on administration, undergoes chemical conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the pharmacologically active pesticide for which it is a propesticide.
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active insecticide for which it is a proinsecticide.
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active fungicide for which it is a profungicide.
A compound that, on administration, must undergo chemical conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the pharmacologically active herbicide for which it is a proherbicide.
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active insecticide for which it is a proacaricide.
A compound that, on administration, must undergo chemical conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the pharmacologically active herbicide savener for which it is a prosafener.
Any inhibitor of S100 calcium-binding protein B.
S100 calcium-binding protein B inhibitors
substance with S100 calcium-binding protein B inhibitor role
A compound that, on administration, undergoes conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the active agent for which it is a pro-agent.
A role borne by a molecule that acts to counteract or neutralise the nerve agent sarin.
substance with antidote to sarin poisoning role
An EC 4.4.1.* (C-S lyase) inhibitor that interferes with the action of 1-aminocyclopropane-1-carboxylate synthase (EC 4.4.1.14).
1-aminocyclopropane-1-carboxylate synthase inhibitor
1-aminocyclopropane-1-carboxylate synthase inhibitors
1-aminocyclopropane-1-carboxylate synthetase inhibitor
1-aminocyclopropane-1-carboxylate synthetase inhibitors
1-aminocyclopropane-1-carboxylic acid synthase inhibitor
1-aminocyclopropane-1-carboxylic acid synthase inhibitors
1-aminocyclopropanecarboxylate synthase inhibitor
1-aminocyclopropanecarboxylate synthase inhibitors
EC 4.4.1.14 (1-aminocyclopropane-1-carboxylate synthase) inhibitors
S-adenosyl-L-methionine methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming) inhibitor
S-adenosyl-L-methionine methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming) inhibitors
S-adenosyl-L-methionine methylthioadenosine-lyase inhibitor
S-adenosyl-L-methionine methylthioadenosine-lyase inhibitors
aminocyclopropanecarboxylate synthase inhibitor
aminocyclopropanecarboxylate synthase inhibitors
aminocyclopropanecarboxylic acid synthase inhibitor
aminocyclopropanecarboxylic acid synthase inhibitors
substance with EC 4.4.1.14 (1-aminocyclopropane-1-carboxylate synthase) inhibitor role
Any compound that inihibits the mammalian protein, eukaryotic initiation factor 4F.
eukaryotic initiation factor 4F inhibitors
substance with eukaryotic initiation factor 4F inhibitor role
Any inhibitor of bromodomain-containing protein 4 (BRD4).
bromodomain-containing protein 4 inhibitors
substance with bromodomain-containing protein 4 inhibitor role
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the activity of receptor protein serine/threonine kinase (EC 2.7.11.30).
ATP:[receptor-protein] phosphotransferase inhibitor
ATP:[receptor-protein] phosphotransferase inhibitors
EC 2.7.11.30 (receptor protein serine/threonine kinase) inhibitors
inhibitor of receptor protein serine/threonine kinase
receptor protein serine/threonine kinase (EC 2.7.11.30) inhibitor
receptor protein serine/threonine kinase (EC 2.7.11.30) inhibitors
receptor protein serine/threonine kinase inhibitor
receptor protein serine/threonine kinase inhibitors
receptor serine/threonine protein kinase inhibitor
receptor serine/threonine protein kinase inhibitors
receptor type I serine/threonine protein kinase inhibitor
receptor type I serine/threonine protein kinase inhibitors
receptor type II serine/threonine protein kinase inhibitor
receptor type II serine/threonine protein kinase inhibitors
substance with EC 2.7.11.30 (receptor protein serine/threonine kinase) inhibitor role
An agonist that binds to and activates capsaicin receptors
transient receptor potential cation channel subfamily V member 1 agonist
transient receptor potential cation channel subfamily V member 1 agonists
substance with capsaicin receptor agonist role
A cardiovascular drug that tends to raise reduced blood pressure.
substance with antihypotensive agent role
An agonist at the transient receptor potential cation channel A1 (TRPA1).
transient receptor potential ankyrin 1 agonist
transient receptor potential ankyrin 1 agonists
transient receptor potential cation channel A1 agonist
transient receptor potential cation channel A1 agonists
substance with TRPA1 channel agonist role
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of cystathionine gamma-synthase (EC 2.5.1.48).
4-O-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase inhibitor
4-O-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase inhibitors
EC 2.5.1.48 (cystathionine gamma-synthase) inhibitors
O(4)-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase inhibitor
O(4)-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase inhibitors
O-succinyl-L-homoserine succinate-lyase (adding cysteine) inhibitor
O-succinyl-L-homoserine succinate-lyase (adding cysteine) inhibitors
O-succinylhomoserine (thiol)-lyase inhibitor
O-succinylhomoserine (thiol)-lyase inhibitors
O-succinylhomoserine synthase inhibitors
O-succinylhomoserine synthetase inhibitor
O-succinylhomoserine synthetase inhibitors
homoserine O-transsuccinylase inhibitors
substance with EC 2.5.1.48 (cystathionine gamma-synthase) inhibitor role
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of 11beta-hydroxysteroid dehydrogenase (EC 1.1.1.146).
11beta-hydroxy steroid dehydrogenase inhibitor
11beta-hydroxy steroid dehydrogenase inhibitors
11beta-hydroxysteroid dehydrogenase inhibitor
11beta-hydroxysteroid dehydrogenase inhibitors
11beta-hydroxysteroid dehydrogenase type 1 inhibitor
11beta-hydroxysteroid dehydrogenase type 1 inhibitors
11beta-hydroxysteroid:NADP(+) 11-oxidoreductase inhibitor
11beta-hydroxysteroid:NADP(+) 11-oxidoreductase inhibitors
EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitors
beta-hydroxysteroid dehydrogenase inhibitor
beta-hydroxysteroid dehydrogenase inhibitors
corticosteroid 11beta-dehydrogenase inhibitor
corticosteroid 11beta-dehydrogenase inhibitors
dehydrogenase, 11beta-hydroxy steroid inhibitor
dehydrogenase, 11beta-hydroxy steroid inhibitors
substance with EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor role
Any mammalian metabolite produced during a metabolic reaction in Papio hamadryas.
substance with Papio hamadryas metabolite role
Any psychotropic drug that induces anxiety or panic.
An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of caspase-3 (EC 3.4.22.56).
substance with EC 3.4.22.56 (caspase-3) inhibitor role
Any compound that can disrupt the functions of the endocrine (hormone) system
Any inhibitor of ATPase motor cytoplasmic dynein.
ATPase motor cytoplasmic dynein inhibitors
substance with ATPase motor cytoplasmic dynein inhibitor role
A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water.
substance with neuropeptide Y2 receptor agonist role
Any pathway inhibitor that acts on the carotenoid biosynthesis pathway.
substance with carotenoid biosynthesis inhibitor role
Any inhibitor that interferes with the action of the protein RhoA.
Ras homolog gene family, member A inhibitor
Ras homolog gene family, member A inhibitors
Any inhibitor that interferes with the action of the protein RhoC.
Ras homolog gene family, member C inhibitor
Ras homolog gene family, member C inhibitors
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD+ or NADP+ acceptor) inhibitor that interferes with the action of 7alpha-hydroxysteroid dehydrogenase (EC 1.1.1.159).
7alpha-hydroxy steroid dehydrogenase inhibitor
7alpha-hydroxy steroid dehydrogenase inhibitors
7alpha-hydroxysteroid dehydrogenase inhibitor
7alpha-hydroxysteroid dehydrogenase inhibitors
7alpha-hydroxysteroid:NAD+ 7-oxidoreductase inhibitor
7alpha-hydroxysteroid:NAD+ 7-oxidoreductase inhibitors
EC 1.1.1.159 (7alpha-hydroxysteroid dehydrogenase) inhibitors
substance with EC 1.1.1.159 (7alpha-hydroxysteroid dehydrogenase) inhibitor role
A hormone antagonist that acts at angiotensin receptors.
substance with angiotensin receptor agonist role
Any compound that induces the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell).
An antagonist that binds to and blocks the activity of prostaglandin receptors.
substance with prostaglandin receptor antagonist role
An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of any carbon-nitrogen ligases with glutamine as amido-N-donor (EC 6.3.5.*).
EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitors
substance with EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor role
An EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor that interferes with the action of carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5).
EC 6.3.5.5 [carbamoyl-phosphate synthase (glutamine-hydrolysing)] inhibitors
HCO3(-):L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) inhibitor
HCO3(-):L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) inhibitors
carbamoyl phosphate synthetase inhibitor
carbamoyl phosphate synthetase inhibitors
carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) inhibitor
carbamoyl-phosphate synthase (glutamine-hydrolysing) (EC 6.3.5.5) inhibitors
carbamoyl-phosphate synthetase (glutamine-hydrolysing) inhibitor
carbamoyl-phosphate synthetase (glutamine-hydrolysing) inhibitors
carbamoylphosphate synthetase II inhibitor
carbamoylphosphate synthetase II inhibitors
carbamyl phosphate synthetase (glutamine) inhibitor
carbamyl phosphate synthetase (glutamine) inhibitors
carbon-dioxide:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) inhibitor
carbon-dioxide:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) inhibitors
glutamine-dependent carbamoyl-phosphate synthase inhibitor
glutamine-dependent carbamoyl-phosphate synthase inhibitors
glutamine-dependent carbamyl phosphate synthetase inhibitor
glutamine-dependent carbamyl phosphate synthetase inhibitors
hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) inhibitor
hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) inhibitors
substance with EC 6.3.5.5 [carbamoyl-phosphate synthase (glutamine-hydrolysing)] inhibitor role
Any EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of 'other carbon--nitrogen ligases.
EC 6.3.4.* (other carbon--nitrogen ligases) inhibitors
substance with EC 6.3.4.* (other carbon--nitrogen ligases) inhibitor role
Any EC 6.3.4.* (other carbon--nitrogen ligases) inhibitor that interferes with the action of CTP synthase (glutamine hydrolyzing) (EC 6.3.4.2).
CTP synthase (glutamine hydrolyzing) (EC6.3.4.2) inhibitor
CTP synthase (glutamine hydrolyzing) (EC6.3.4.2) inhibitors
CTP synthase (glutamine hydrolyzing) inhibitor
CTP synthase (glutamine hydrolyzing) inhibitors
EC 6.3.4.2 [CTP synthase (glutamine hydrolyzing)] inhibitors
UTP:L-glutamine amido-ligase (ADP-forming) inhibitor
UTP:L-glutamine amido-ligase (ADP-forming) inhibitors
cytidine triphosphate synthetase inhibitor
cytidine triphosphate synthetase inhibitors
substance with EC 6.3.4.2 [CTP synthase (glutamine hydrolyzing)] inhibitor role
Any EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor that interferes with the action of phosphoribosylformylglycinamidine synthase (EC 6.3.5.3).
2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming) inhibitor
2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming) inhibitors
5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming) inhibitor
5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming) inhibitors
EC 6.3.5.3 (phosphoribosylformylglycinamidine synthase) inhibitors
N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming) inhibitor
N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming) inhibitors
formylglycinamide ribonucloetide amidotransferase inhibitor
formylglycinamide ribonucloetide amidotransferase inhibitors
formylglycinamide ribotide amidotransferase inhibitor
formylglycinamide ribotide amidotransferase inhibitors
phosphoribosylformylglycinamidine synthase inhibitor
phosphoribosylformylglycinamidine synthase inhibitors
phosphoribosylformylglycinamidine synthetase inhibitor
phosphoribosylformylglycinamidine synthetase inhibitors
phosphoribosylformylglycineamidine synthetase inhibitor
phosphoribosylformylglycineamidine synthetase inhibitors
substance with EC 6.3.5.3 (phosphoribosylformylglycinamidine synthase) inhibitor role
An EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor that interferes with the action of GMP synthase (glutamine-hydrolysing) (EC 6.3.5.2).
EC 6.3.5.2 [GMP synthase (glutamine-hydrolysing)] inhibitors
GMP synthase (glutamine-hydrolysing) inhibitor
GMP synthase (glutamine-hydrolysing) inhibitors
GMP synthetase (glutamine-hydrolysing) inhibitor
GMP synthetase (glutamine-hydrolysing) inhibitors
guanosine 5'-monophosphate synthetase inhibitor
guanosine 5'-monophosphate synthetase inhibitors
guanosine monophosphate synthetase (glutamine-hydrolyzing) inhibitor
guanosine monophosphate synthetase (glutamine-hydrolyzing) inhibitors
guanylate synthetase (glutamine-hydrolyzing) inhibitor
guanylate synthetase (glutamine-hydrolyzing) inhibitors
xanthosine 5'-phosphate amidotransferase inhibitor
xanthosine 5'-phosphate amidotransferase inhibitors
xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming) inhibitor
xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming) inhibitors
substance with EC 6.3.5.2 [GMP synthase (glutamine-hydrolysing)] inhibitor role
An antagonist that acts on glutamine receptors.
substance with glutamine antagonist role
An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of ribulose-bisphosphate carboxylase (EC 4.1.1.39).
3-phospho-D-glycerate carboxy-lyase (dimerizing) inhibitor
3-phospho-D-glycerate carboxy-lyase (dimerizing) inhibitors
3-phospho-D-glycerate carboxy-lyase (dimerizing; D-ribulose-1,5-bisphosphate-forming) inhibitor
3-phospho-D-glycerate carboxy-lyase (dimerizing; D-ribulose-1,5-bisphosphate-forming) inhibitors
D-ribulose 1,5-bisphosphate carboxylase inhibitor
D-ribulose 1,5-bisphosphate carboxylase inhibitors
D-ribulose 1,5-diphosphate carboxylase inhibitor
D-ribulose 1,5-diphosphate carboxylase inhibitors
EC 4.1.1.39 (ribulose-bisphosphate carboxylase) inhibitors
diphosphoribulose carboxylase inhibitors
ribulose 1,5-bisphosphate carboxylase inhibitor
ribulose 1,5-bisphosphate carboxylase inhibitors
ribulose 1,5-bisphosphate carboxylase/oxygenase inhibitor
ribulose 1,5-bisphosphate carboxylase/oxygenase inhibitors
ribulose 1,5-diphosphate carboxylase inhibitor
ribulose 1,5-diphosphate carboxylase inhibitors
ribulose 1,5-diphosphate carboxylase/oxygenase inhibitor
ribulose 1,5-diphosphate carboxylase/oxygenase inhibitors
ribulose bisphosphate carboxylase/oxygenase inhibitor
ribulose bisphosphate carboxylase/oxygenase inhibitors
ribulose diphosphate carboxylase inhibitor
ribulose diphosphate carboxylase inhibitors
ribulose diphosphate carboxylase/oxygenase inhibitor
ribulose diphosphate carboxylase/oxygenase inhibitors
ribulose-bisphosphate carboxylase inhibitor
ribulose-bisphosphate carboxylase inhibitors
substance with EC 4.1.1.39 (ribulose-bisphosphate carboxylase) inhibitor role
Any EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of amidophosphoribosyltransferase (EC 2.4.2.14).
5'-phosphoribosylpyrophosphate amidotransferase inhibitor
5'-phosphoribosylpyrophosphate amidotransferase inhibitors
5-phospho-beta-D-ribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating) inhibitor
5-phospho-beta-D-ribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating) inhibitors
5-phosphoribosyl-1-pyrophosphate amidotransferase inhibitor
5-phosphoribosyl-1-pyrophosphate amidotransferase inhibitors
5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating) inhibitor
5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating) inhibitors
5-phosphororibosyl-1-pyrophosphate amidotransferase inhibitor
5-phosphororibosyl-1-pyrophosphate amidotransferase inhibitors
EC 2.4.2.14 (amidophosphoribosyltransferase) inhibitors
alpha-5-phosphoribosyl-1-pyrophosphate amidotransferase inhibitor
alpha-5-phosphoribosyl-1-pyrophosphate amidotransferase inhibitors
amidophosphoribosyltransferase (EC 2.4.2.14) inhibitor
amidophosphoribosyltransferase (EC 2.4.2.14) inhibitors
amidophosphoribosyltransferase inhibitor
amidophosphoribosyltransferase inhibitors
glutamine 5-phosphoribosylpyrophosphate amidotransferase inhibitor
glutamine 5-phosphoribosylpyrophosphate amidotransferase inhibitors
glutamine phosphoribosyldiphosphate amidotransferase inhibitor
glutamine phosphoribosyldiphosphate amidotransferase inhibitors
glutamine phosphoribosylpyrophosphate amidotransferase inhibitor
glutamine phosphoribosylpyrophosphate amidotransferase inhibitors
glutamine ribosylpyrophosphate 5-phosphate amidotransferase inhibitor
glutamine ribosylpyrophosphate 5-phosphate amidotransferase inhibitors
phosphoribose pyrophosphate amidotransferase inhibitor
phosphoribose pyrophosphate amidotransferase inhibitors
phosphoribosyl pyrophosphate amidotransferase inhibitor
phosphoribosyl pyrophosphate amidotransferase inhibitors
phosphoribosyldiphosphate 5-amidotransferase inhibitor
phosphoribosyldiphosphate 5-amidotransferase inhibitors
phosphoribosylpyrophosphate glutamyl amidotransferase inhibitor
phosphoribosylpyrophosphate glutamyl amidotransferase inhibitors
substance with EC 2.4.2.14 (amidophosphoribosyltransferase) inhibitor role
Any EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor that interferes with the action of NAD(+) synthase (glutamine-hydrolysing) (EC 6.3.5.1).
EC 6.3.5.1 [NAD(+) synthase (glutamine-hydrolysing)] inhibitors
NAD synthetase (glutamine-hydrolysing) inhibitor
NAD synthetase (glutamine-hydrolysing) inhibitors
NAD(+) synthase (glutamine-hydrolysing) (EC 6.3.5.1) inhibitor
NAD(+) synthase (glutamine-hydrolysing) (EC 6.3.5.1) inhibitors
NAD(+) synthase (glutamine-hydrolysing) inhibitor
NAD(+) synthase (glutamine-hydrolysing) inhibitors
NAD(+) synthetase (glutamine-hydrolyzing) inhibitor
NAD(+) synthetase (glutamine-hydrolyzing) inhibitors
deamido-NAD(+):L-glutamine amido-ligase (AMP-forming) inhibitor
deamido-NAD(+):L-glutamine amido-ligase (AMP-forming) inhibitors
desamidonicotinamide adenine dinucleotide amidotransferase inhibitor
desamidonicotinamide adenine dinucleotide amidotransferase inhibitors
nicotinamide adenine dinucleotide synthetase (glutamine) inhibitor
nicotinamide adenine dinucleotide synthetase (glutamine) inhibitors
substance with EC 6.3.5.1 [NAD(+) synthase (glutamine-hydrolysing)] inhibitor role
Any EC 6.3.5.* (carbon-nitrogen ligases with glutamine as amido-N-donor) inhibitor that interferes with the action of asparagine synthase (glutamine-hydrolysing), EC 6.3.5.4.
EC 6.3.5.4 [asparagine synthase (glutamine-hydrolysing)] inhibitors
L-aspartate:L-glutamine amido-ligase (AMP-forming) inhibitor
L-aspartate:L-glutamine amido-ligase (AMP-forming) inhibitors
asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) inhibitor
asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) inhibitors
asparagine synthase (glutamine-hydrolysing) inhibitor
asparagine synthase (glutamine-hydrolysing) inhibitors
asparagine synthetase (glutamine-hydrolysing) inhibitor
asparagine synthetase (glutamine-hydrolysing) inhibitors
glutamine-dependent asparagine synthetase inhibitor
glutamine-dependent asparagine synthetase inhibitors
substance with EC 6.3.5.4 [asparagine synthase (glutamine-hydrolysing)] inhibitor role
Any compound that interferes with bacterial communication (quorum sensing, QS).
substance with quorum sensing inhibitor role
An agonist that binds to and activates thromboxane A2 receptors.
substance with thromboxane A2 agonist role
An EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor that inhibits the expression of protein kinase RNA-like endoplasmic reticulum kinase.
PKR-like endoplasmic reticulum kinase inhibitor
PKR-like endoplasmic reticulum kinase inhibitors
protein kinase R-like endoplasmic reticulum kinase inhibitor
protein kinase R-like endoplasmic reticulum kinase inhibitors
An that interferes with the activity of any of the actin-binding kinases that phosphorylate members of the ADF/cofilin family of actin binding and filament severing proteins.
substance with LIM kinase inhibitor role
substance with cis-Golgi ArfGEF GBF inhibitor role
An agonist that activates IP3 receptors.
D-myo-inositol 1,4,5-trisphosphate receptor agonist
D-myo-inositol 1,4,5-trisphosphate receptor agonists
inositol trisphosphate receptor agonists
substance with IP3 receptor agonist role
An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of protein O-GlcNAc transferase (EC 2.4.1.255).
EC 2.4.1.255 (protein O-GlcNAc transferase) inhibitors
O-linked N-acetylglucosaminyltransferase inhibitor
O-linked N-acetylglucosaminyltransferase inhibitors
UDP-N-acetyl-D-glucosamine:protein-O-beta-N-acetyl-D-glucosaminyl transferase inhibitor
UDP-N-acetyl-D-glucosamine:protein-O-beta-N-acetyl-D-glucosaminyl transferase inhibitors
protein O-GlcNAc transferase (EC 2.4.1.255) inhibitor
protein O-GlcNAc transferase (EC 2.4.1.255) inhibitors
protein O-linked beta-N-acetylglucosamine transferase inhibitor
protein O-linked beta-N-acetylglucosamine transferase inhibitors
uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase inhibitor
uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase inhibitors
substance with EC 2.4.1.255 (protein O-GlcNAc transferase) inhibitor role
An antagonist that attaches to and blocks melanin-concentrating hormone receptors.
melanin-concentrating hormone receptor antagonists
substance with melanin-concentrating hormone receptor antagonist role
An antagonist that attaches to and blocks nicotinic acid adenine dinucleotide phosphate receptors.
nicotinic acid adenine dinucleotide phosphate receptor antagonists
substance with nicotinic acid adenine dinucleotide phosphate receptor antagonist role
A probe that is a small labelled and chemical active peptide which has been structurally modified for reacting with, for example, the beta-lactam moieties of various penicillin-type compounds.
substance with EC 1.14.17.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen and with reduced ascorbate as one donor, and incorporation of one atom of oxygen) inhibitor role
An EC 1.14.17.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen and with reduced ascorbate as one donor, and incorporation of one atom of oxygen) inhibitor that interferes with the action of dopamine monooxygenase (EC 1.14.17.1).
(3,4-dihydroxyphenethylamine)beta-mono-oxygenase inhibitor
(3,4-dihydroxyphenethylamine)beta-mono-oxygenase inhibitors
3,4-dihydroxyphenethylamine beta-oxidase inhibitor
3,4-dihydroxyphenethylamine beta-oxidase inhibitors
3,4-dihydroxyphenethylamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating) inhibitor
3,4-dihydroxyphenethylamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating) inhibitors
4-(2-aminoethyl)pyrocatechol beta-oxidase inhibitor
4-(2-aminoethyl)pyrocatechol beta-oxidase inhibitors
EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitors
MDBH (membrane-associated dopamine beta-monooxygenase) inhibitor
MDBH (membrane-associated dopamine beta-monooxygenase) inhibitors
SDBH (soluble dopamine beta-monooxygenase) inhibitor
SDBH (soluble dopamine beta-monooxygenase) inhibitors
dopamine beta-monooxygenase (EC 1.14.17.1) inhibitor
dopamine beta-monooxygenase (EC 1.14.17.1) inhibitors
oxygenase, dopamine beta-mono-phenylamine beta-hydroxylase inhibitor
oxygenase, dopamine beta-mono-phenylamine beta-hydroxylase inhibitors
substance with EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor role
An agent that inhibits the passage of cations through the transient receptor potential (TRP) channels.
transient receptor potential channel blocker
transient receptor potential channel blockers
A chemical compound that causes a substantial proportion of exposed people or animals to develop an allergic reaction in normal tissue after repeated exposure to the compound.
An agonist that binds to and activates vitamin D receptors
substance with vitamin D receptor agonist role
An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of enoyl-[acyl-carrier-protein] reductase (NADH), EC 1.3.1.9.
EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitors
NADH-enoyl acyl carrier protein reductase inhibitor
NADH-enoyl acyl carrier protein reductase inhibitors
NADH-specific enoyl-ACP reductase inhibitor
NADH-specific enoyl-ACP reductase inhibitors
acyl-[acyl-carrier-protein]:NAD+ oxidoreductase inhibitor
acyl-[acyl-carrier-protein]:NAD+ oxidoreductase inhibitors
enoyl-[acyl carrier protein] reductase inhibitor
enoyl-[acyl carrier protein] reductase inhibitors
substance with EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor role
An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of ornithine decarboxylase (EC 4.1.1.17).
EC 4.1.1.17 (ornithine decarboxylase) inhibitors
L-ornithine carboxy-lyase (putrescine-forming) inhibitor
L-ornithine carboxy-lyase (putrescine-forming) inhibitors
substance with EC 4.1.1.17 (ornithine decarboxylase) inhibitor role
Any plant metabolite that is produced by the genus Jacobaea.
An agonist that binds to and activates lysophosphatidic acid 3 receptors.
lysophosphatidic acid receptor 3 agonists
substance with lysophosphatidic acid receptor 3 agonist role
An apoptosis inducer that works by selectively inhibiting survivin (BIRC5) gene promoter activity so as to down-regulate survivin, a protein that inhibits apoptosis, so leading to induction of apoptosis.
substance with survivin suppressant role
An agonist at the transient receptor potential vanilloid 4 (TRPV4).
OSM9-like transient receptor potential channel, member 4 agonist
OSM9-like transient receptor potential channel, member 4 agonists
transient receptor potential cation channel subfamily V member 4 agonist
transient receptor potential cation channel subfamily V member 4 agonists
transient receptor potential vanilloid 4 agonists
vanilloid-receptor related osmotically activated channel agonist
vanilloid-receptor related osmotically activated channel agonists
Any plant metabolite that is produced by Camellia sinensis.
substance with Camellia sinensis metabolite role
Any plant metabolite that is produced by rapeseed (Brassica napus).
substance with Brassica napus metabolite role
Any antimicrobial agent whose activity is dependent on the presence of calcium ions.
substance with calcium-dependent antibiotics role
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of any malate dehydrogenase (EC 1.1.1.37).
(S)-malate:NAD(+) oxidoreductase inhibitor
(S)-malate:NAD(+) oxidoreductase inhibitors
EC 1.1.1.37 (malate dehydrogenase) inhibitors
L-malate-NAD(+) oxidoreductase inhibitor
L-malate-NAD(+) oxidoreductase inhibitors
NAD-dependent malate dehydrogenase inhibitor
NAD-dependent malate dehydrogenase inhibitors
NAD-dependent malic dehydrogenase inhibitor
NAD-dependent malic dehydrogenase inhibitors
NAD-linked malate dehydrogenase inhibitor
NAD-linked malate dehydrogenase inhibitors
NAD-specific malate dehydrogenase inhibitor
NAD-specific malate dehydrogenase inhibitors
malate dehydrogenase (EC 1.1.1.37) inhibitor
malate dehydrogenase (EC 1.1.1.37) inhibitors
substance with EC 1.1.1.37 (malate dehydrogenase) inhibitor role
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
substance with specialised pro-resolving mediator role
An antagonist at the neurokinin-3 receptor.
substance with neurokinin-3 receptor antagonist role
An agonist that binds to and deactivates the tropomyosin-related kinase B (TrkB) receptor, the main signaling receptor of the neurotrophin brain-derived neurotrophic factor (BDNF).
tropomyosin-related kinase B receptor agonists
substance with tropomyosin-related kinase B receptor agonist role
An agonist at the transient receptor potential vanilloid 1 (TRPV1).
transient receptor potential vanilloid 1 agonist
transient receptor potential vanilloid 1 agonists
Any plant metabolite that is produced by Arabidopsis thaliana.
substance with Arabidopsis thaliana metabolite role
Any inhibitor of secreted frizzled-related protein 1 (SFRP1). The level of SFRP1 affects osteoblast apoptosis and proliferation, so SFRP1 inhibitors have the potential to be used for the treatment of osteoporosis or other bone related disorders.
secreted frizzled-related protein 1 inhibitors
secreted frizzled-related protein-1 inhibitor
secreted frizzled-related protein-1 inhibitors
substance with secreted frizzled-related protein 1 inhibitor role
Any pathway inhibitor that inhibits the Hedgehog signalling pathway.
substance with Hedgehog signaling pathway inhibitor role
An inhibitor of any of the glioma-associated oncogene (GLI) proteins.
substance with glioma-associated oncogene inhibitor role
An antagonist that binds to and deactivates neuropeptide FF receptors.
substance with neuropeptide FF receptor antagonist role
An agonist that activates neuropeptide FF (NPFF) receptors.
substance with neuropeptide FF receptor agonist role
An agonist that acts at the kisspeptin receptor (KISS1R).
substance with kisspeptin receptor agonist role
A mitochondrial cytochrome-bc1 complex inhibitor that acts at the Quinone 'outer' (Qo) binding site of the cytochrome-bc1 complex.
substance with quinone outside inhibitor role
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active nematicide for which it is a pronematicide.
An agonist at the 5-hydroxytryptamine 2B (5-HT2B) receptor.
5-hydroxytryptamine 2B receptor agonists
5-hydroxytryptamine receptor 2B agonists
substance with 5-hydroxytryptamine 2B receptor agonist role
An agonist at the 5-hydroxytryptamine 2B (5-HT2C) receptor.
5-hydroxytryptamine 2C receptor agonists
5-hydroxytryptamine receptor 2C agonists
substance with 5-hydroxytryptamine 2C receptor agonist role
Any EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of leukotriene-B4 20-monooxygenase (EC 1.14.14.94).
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (20-hydroxylating) inhibitor
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (20-hydroxylating) inhibitors
EC 1.14.14.94 (leukotriene-B4 20-monooxygenase) inhibitors
leucotriene-B4 omega-hydroxylase inhibitor
leucotriene-B4 omega-hydroxylase inhibitors
leukotriene-B4 20-hydroxylase inhibitors
leukotriene-B4 20-monooxygenase (EC 1.14.14.94) inhibitors
leukotriene-B4 20-monooxygenase inhibitor
leukotriene-B4 20-monooxygenase inhibitors
substance with EC 1.14.14.94 (leukotriene-B4 20-monooxygenase) inhibitor role
Any EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced Fe-S protein as one donor, incorporating 1 O atom) inhibitor that interferes with the action of alkane 1-monooxygenase (EC 1.14.15.3).
EC 1.14.15.3 (alkane 1-monooxygenase) inhibitors
alkane 1-monooxygenase (EC 1.14.15.3) inhibitor
alkane 1-monooxygenase (EC 1.14.15.3) inhibitors
alkane,reduced-rubredoxin:oxygen 1-oxidoreductase inhibitor
alkane,reduced-rubredoxin:oxygen 1-oxidoreductase inhibitors
substance with EC 1.14.15.3 (alkane 1-monooxygenase) inhibitor role
An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of glutamate decarboxylase (EC 4.1.1.15).
EC 4.1.1.15 (glutamate decarboxylase) inhibitors
L-aspartate-alpha-decarboxylase inhibitor
L-aspartate-alpha-decarboxylase inhibitors
L-glutamate 1-carboxy-lyase (4-aminobutanoate-forming) inhibitor
L-glutamate 1-carboxy-lyase (4-aminobutanoate-forming) inhibitors
L-glutamate alpha-decarboxylase inhibitor
L-glutamate alpha-decarboxylase inhibitors
L-glutamic acid decarboxylase inhibitors
gamma-glutamate decarboxylase inhibitors
glutamate decarboxylase (EC 4.1.1.15) inhibitor
glutamate decarboxylase (EC 4.1.1.15) inhibitors
substance with EC 4.1.1.15 (glutamate decarboxylase) inhibitor role
A chemical that inhibits the aggregation of the tau protein (HGNC:MAPT) and its distinct morphological forms (e.g. paired helical fragments (PHFs), straight filaments (SFs), oligomers, or larger aggregates).
substance with tau aggregation inhibitor role
substance with EC 2.5.1.117 (homogentisate solanesyltransferase) inhibitor role
Any transient receptor potential (TRP) channel modulator that modulates the TRPV channels (V = vanilloid). There is strong evidence that action at one or more of this class of proteins is responsible for the insecticidal action of pymetrozine, pyrifluquinazon, and afidopyropen.
transient receptor potential (vanilloid) channel modulator
transient receptor potential (vanilloid) channel modulators
substance with TRPV channel modulator role
An agent that modulates the passage of cations through the transient receptor potential (TRP) channels.
substance with TRP channel modulator role
Any inhibitor of soluble epoxide hydrolase, a bifunctional enzyme that in humans is encoded by the EPHX2 gene.Found in both the cytosol and peroxisomes it binds to specific epoxides and converts them into the corresponding diols.
substance with EC 3.3.2.10 (soluble epoxide hydrolase) inhibitor role
substance with GABAB receptor agonist role
An EC 2.1.* (C1-transferase) inhibitor that interferes with the action of any carboxy- and carbamoyltransferases (EC 2.1.3.*).
EC 2.1.3.* (carboxy- and carbamoyltransferases) inhibitors
EC 2.1.3.* (carboxytransferase and carbamoyltransferase) inhibitor
EC 2.1.3.* (carboxytransferase and carbamoyltransferase) inhibitors
carboxy- and carbamoyltransferase (EC 2.1.3.*) inhibitor
carboxy- and carbamoyltransferase (EC 2.1.3.*) inhibitors
substance with EC 2.1.3.* (carboxy- and carbamoyltransferases) inhibitor role
Any EC 2.1.3.* (carboxy- and carbamoyltransferases) inhibitor that inhibits the action of ornithine carbamoyltransferase (EC 2.1.3.3).
EC 2.1.3.3 (ornithine carbamoyltransferase) inhibitors
L-ornithine carbamoyltransferase inhibitor
L-ornithine carbamoyltransferase inhibitors
L-ornithine carbamyltransferase inhibitor
L-ornithine carbamyltransferase inhibitors
carbamoyl-phosphate:L-ornithine carbamoyltransferase inhibitor
carbamoyl-phosphate:L-ornithine carbamoyltransferase inhibitors
carbamylphosphate-ornithine transcarbamylase inhibitor
carbamylphosphate-ornithine transcarbamylase inhibitors
ornithine carbamoyltransferase (EC 2.1.3.3) inhibitor
ornithine carbamoyltransferase (EC 2.1.3.3) inhibitors
ornithine carbamoyltransferase inhibitor
ornithine carbamoyltransferase inhibitors
ornithine carbamyltransferase inhibitors
substance with EC 2.1.3.3 (ornithine carbamoyltransferase) inhibitor role
A chemical role played by any unwanted chemical substance inside a confined amount of liquid, gas, or solid, which differs from the chemical composition of the material or compound. For example, an impurity can be an undesired by-product of a chemical reaction or manufacturing process, a drug contaminant, or can be created upon degradation during storage.
Any peptide which causes the onset of an allergic reaction.
Any carbohydrate, carbohydrate derivative or derived substituent group which causes the onset of an allergic reaction.
substance with carbohydrate allergen role
Any ceramide which causes the onset of an allergic reaction.
Any EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of sterol 14alpha-demethylase (EC 1.14.14.154).
EC 1.14.14.154 (sterol 14alpha-demethylase) inhibitors
lanosterol 14alpha-demethylase inhibitor
lanosterol 14alpha-demethylase inhibitors
oxidoreductase (14-methyl cleaving) inhibitors
sterol 14alpha-demethylase (EC 1.14.14.154) inhibitor
sterol 14alpha-demethylase (EC 1.14.14.154) inhibitors
sterol,[reduced NADPH--hemoprotein reductase]:oxygen inhibitor
sterol,[reduced NADPH--hemoprotein reductase]:oxygen oxidoreductase (14-methyl cleaving) inhibitor
substance with EC 1.14.14.154 (sterol 14alpha-demethylase) inhibitor role
An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of pyruvate kinase (EC 2.7.1.40).
phosphoenol transphosphorylase inhibitor
phosphoenol transphosphorylase inhibitors
substance with EC 2.7.1.40 (pyruvate kinase) inhibitor role
Any EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced Fe-S protein as one donor, incorporating 1 O atom) inhibitor that interferes with the action of cholesterol monooxygenase (side-chain-cleaving) (EC 1.14.15.6).
C27-side chain cleavage enzyme inhibitor
C27-side chain cleavage enzyme inhibitors
cholesterol monooxygenase (side-chain-cleaving) inhibitor
cholesterol monooxygenase (side-chain-cleaving) inhibitors
cholesterol side-chain cleavage enzyme inhibitor
cholesterol side-chain cleavage enzyme inhibitors
cholesterol side-chain-cleaving enzyme inhibitor
cholesterol side-chain-cleaving enzyme inhibitors
substance with EC 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving) inhibitor role
Any EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of L-amino-acid oxidase (EC 1.4.3.2).
EC 1.4.3.2 (L-amino-acid oxidase) inhibitors
L-amino-acid oxidase inhibitor (EC 1.4.3.2) inhibitor
L-amino-acid oxidase inhibitor (EC 1.4.3.2) inhibitors
L-amino-acid:oxygen oxidoreductase (deaminating) inhibitor
L-amino-acid:oxygen oxidoreductase (deaminating) inhibitors
substance with EC 1.4.3.2 (L-amino-acid oxidase) inhibitor role
substance with EC 2.6.1.2 (alanine transaminase) inhibitor role
An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of 6-phosphofructo-2-kinase (EC 2.7.1.105).
6-phosphofructo-2-kinase (phosphorylating) inhibitor
6-phosphofructo-2-kinase (phosphorylating) inhibitors
fructose 6-phosphate 2-kinase inhibitors
substance with EC 2.7.1.105 (6-phosphofructo-2-kinase) inhibitor role
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of retinoid isomerohydrolase (EC 3.1.1.64).
EC 3.1.1.64 (retinoid isomerohydrolase) inhibitors
all-trans-retinol isomerase:hydrolase inhibitor
all-trans-retinol isomerase:hydrolase inhibitors
all-trans-retinyl-palmitate hydrolase inhibitor
all-trans-retinyl-palmitate hydrolase inhibitors
all-trans-retinylester 11-cis isomerohydrolase inhibitor
all-trans-retinylester 11-cis isomerohydrolase inhibitors
substance with EC 3.1.1.64 (retinoid isomerohydrolase) inhibitor role
An antigenic substance produced in tumour cells, which triggers an immune response in the host.
cluster of differentiation 88 antagonist
cluster of differentiation 88 antagonists
complement component 5a receptor 1 antagonist
complement component 5a receptor 1 antagonists
substance with C5a receptor antagonist role
substance with EC 3.6.5.2 (small monomeric GTPase) inhibitor role
An antagonist that binds to and blocks sphingosine 1-phosphate receptors, a class of G protein-coupled receptors that are targets of the lipid signalling molecule sphingosine-1-phosphate (S1P).
sphingosine 1-phosphate receptor antagonist
sphingosine 1-phosphate receptor antagonists
sphingosine-1-phosphate receptor antagonists
substance with sphingosine-1-phosphate receptor antagonist role
Any sphingosine-1-phosphate receptor (S1PR) antagonist that acts as an antagonist towards the subtype 3 receptors (S1PR3).
sphingosine-1-phosphate receptor 3 antagonists
substance with sphingosine-1-phosphate receptor 3 antagonist role
Any sphingosine-1-phosphate receptor (S1PR) antagonist that acts as an antagonist for the subtype 1 receptors (S1PR1).
sphingosine-1-phosphate receptor 1 antagonists
substance with sphingosine-1-phosphate receptor 1 antagonist role
An agent that destroy spermatozoa in the male genitalia and block spermatogenesis.
substance with antispermatogenic agent role
Any inhibitor that interferes with the synthesis of hyaluronic acid (HA, also known as hyaluronan).
substance with hyaluronan synthesis inhibitor role
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of any isocitrate dehydrogenase (EC 1.1.1.42).
NADP(+)-linked isocitrate dehydrogenase inhibitor
NADP(+)-linked isocitrate dehydrogenase inhibitors
NADP-dependent isocitrate dehydrogenase inhibitor
NADP-dependent isocitrate dehydrogenase inhibitors
NADP-dependent isocitric dehydrogenase inhibitor
NADP-dependent isocitric dehydrogenase inhibitors
NADP-linked isocitrate dehydrogenase inhibitor
NADP-linked isocitrate dehydrogenase inhibitors
NADP-specific isocitrate dehydrogenase inhibitor
NADP-specific isocitrate dehydrogenase inhibitors
dual-cofactor-specific isocitrate dehydrogenase inhibitor
dual-cofactor-specific isocitrate dehydrogenase inhibitors
isocitrate (NADP) dehydrogenase inhibitor
isocitrate (NADP) dehydrogenase inhibitors
isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase inhibitor
isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase inhibitors
isocitrate dehydrogenase (NADP(+)) inhibitor
isocitrate dehydrogenase (NADP(+)) inhibitors
isocitrate dehydrogenase (NADP-dependent) inhibitor
isocitrate dehydrogenase (NADP-dependent) inhibitors
triphosphopyridine nucleotide-linked isocitrate dehydrogenase-oxalosuccinate carboxylase inhibitor
triphosphopyridine nucleotide-linked isocitrate dehydrogenase-oxalosuccinate carboxylase inhibitors
substance with EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor role
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of any polo kinase (EC 2.7.11.21).
serine/threonine-specific Drosophila kinase polo inhibitor
serine/threonine-specific Drosophila kinase polo inhibitors
substance with EC 2.7.11.21 (polo kinase) inhibitor role
Any inhibitor that acts on uncoupling protein.
mitochondrial uncoupling protein inhibitor
mitochondrial uncoupling protein inhibitors
substance with uncoupling protein inhibitor role
An antogonist that blocks C-X-C chemokine receptor type 4 (CXCR-4).
C-X-C chemokine receptor type 4 antagonists
C-X-C motif chemokine receptor 4 antagonist
C-X-C motif chemokine receptor 4 antagonists
chemokine (C-X-C motif) receptor 4 antagonist
chemokine (C-X-C motif) receptor 4 antagonists
substance with C-X-C chemokine receptor type 4 antagonist role
substance with GABAA receptor antagonist role
Any inhibitor that acts on forkhead box protein O1 (FOXO1).
substance with forkhead box protein O1 inhibitor role
Any EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor that inhibits the action of aspartate-semialdehyde dehydrogenase (EC 1.2.1.11).
EC 1.2.1.11 (aspartate-semialdehyde dehydrogenase) inhibitors
L-aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating) inhibitor
L-aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating) inhibitors
L-aspartate-beta-semialdehyde:NADP oxidoreductase (phosporylating) inhibitor
L-aspartate-beta-semialdehyde:NADP oxidoreductase (phosporylating) inhibitors
aspartate semialdehyde dehydrogenase inhibitor
aspartate semialdehyde dehydrogenase inhibitors
aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) inhibitor
aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) inhibitors
aspartate-semialdehyde dehydrogenase inhibitor
aspartate-semialdehyde dehydrogenase inhibitors
aspartic beta-semialdehyde dehydrogenase inhibitor
aspartic beta-semialdehyde dehydrogenase inhibitors
aspartic semialdehyde dehydrogenase inhibitor
aspartic semialdehyde dehydrogenase inhibitors
substance with EC 1.2.1.11 (aspartate-semialdehyde dehydrogenase) inhibitor role
A cardiovascular drug that prevents atherosclerosis (a disease in which the inside of an artery narrows due to the build up of plaque). Compare with antiatherogenic agent.
substance with antiatherosclerotic agent role
An agonist at the 5-hydroxytryptamine 2A (5-HT2A) receptor.
5-hydroxytryptamine 2A receptor agonists
5-hydroxytryptamine receptor 2A agonists
substance with 5-hydroxytryptamine 2A receptor agonist role
substance with ryanodine receptor antagonist role
A cannabinoid receptor agonist that binds to and activates type 2 cannabinoid receptors.
substance with CB2 receptor agonist role
Any substance that produces or enhances dream-like states of consciousness.
An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of SARS coronavirus main proteinase (EC 3.4.22.69).
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitors
SARS coronavirus 3CL protease inhibitors
SARS coronavirus main peptidase inhibitor
SARS coronavirus main peptidase inhibitors
SARS coronavirus main protease inhibitor
SARS coronavirus main protease inhibitors
SARS coronavirus main proteinase inhibitor
SARS coronavirus main proteinase inhibitors
severe acute respiratory syndrome coronavirus main protease inhibitor
severe acute respiratory syndrome coronavirus main protease inhibitors
substance with EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor role
Any EC 3.4.17.* (metallocarboxypeptidase) inhibitor that inhibits the action of angiotensin-converting enzyme 2 (EC 3.4.17.23).
EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitor
EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitors
angiotensin converting enzyme 2 inhibitor
angiotensin converting enzyme 2 inhibitors
angiotensin converting enzyme-2 inhibitor
angiotensin converting enzyme-2 inhibitors
angiotensin-converting enzyme 2 inhibitor
angiotensin-converting enzyme 2 inhibitors
substance with EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitor role
Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that inhibits the action of a metallocarboxypeptidase (EC 3.4.17.*).
EC 3.4.17* (metallocarboxypeptidase) inhibitor
EC 3.4.17* (metallocarboxypeptidase) inhibitors
substance with EC 3.4.17* (metallocarboxypeptidase) inhibitor role
Any inhibitor added to nitrogen fertilizers which can reduce the rate at which ammonium is converted to nitrate. Under appropriate conditions, this can help reduce nitrogen losses through denitrification and leaching.
substance with nitrification inhibitor role
A reagent used in electron paramagnetic resonance (EPR) spectroscopy to react covalently with radical products whose half-life is be too short to detect. The resulting adducts are more stable enabling their paramagnetic resonance spectra to be obtained.
substance with spin trapping reagent role
Any agent that induces nausea and vomiting.
Any antiviral agent which inhibits the activity of coronaviruses.
substance with anticoronaviral agent role
An EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor that interferes with the action of ATP citrate synthase (EC 2.3.3.8).
EC 2.3.3.8 (ATP citrate synthase) inhibitor
ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO(-)->acetyl-CoA] (ATP-dephosphorylating) inhibitor
ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO(-)->acetyl-CoA] (ATP-dephosphorylating) inhibitors
EC 2.3.3.8 (ATP citrate synthase) inhibitors
acetyl-CoA:oxaloacetate acetyltransferase (isomerizing, ADP-phosphorylating) inhibitor
acetyl-CoA:oxaloacetate acetyltransferase (isomerizing, ADP-phosphorylating) inhibitors
adenosine triphosphate citrate lyase inhibitor
adenosine triphosphate citrate lyase inhibitors
substance with EC 2.3.3.8 (ATP citrate synthase) inhibitor role
An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the activity of pancreatic elastase (EC 3.4.21.36).
EC 3.4.21.36 (pancreatic elastase) inhibitors
pancreatic elastase (EC 3.4.21.36) inhibitor
pancreatic elastase (EC 3.4.21.36) inhibitors
substance with EC 3.4.21.36 (pancreatic elastase) inhibitor role
An antogonist that blocks chemokine receptor 2 (CCR2).
C-C chemokine receptor type 2 antagonist
C-C chemokine receptor type 2 antagonists
substance with chemokine receptor 2 antagonist role
Any compound that activates Sarcoplasmic/Endoplasmic Reticulum Calcium-ATPase (EC 7.2.2.10).
Sarcoplasmic/Endoplasmic Reticulum Calcium-ATPase activator
Sarcoplasmic/Endoplasmic Reticulum Calcium-ATPase activators
A molecular entity that can transfer an electron to another molecular entity.
A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity.
A topoisomerase inhibitor that inhibits DNA topoisomerase II.
substance with topoisomerase II inhibitor role
An agonist that selectively binds to and activates mucosal associated invariant T cells (MAIT cells).
mucosal associated invariant T cell agonist
mucosal associated invariant T cell agonists
An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of furin (EC 3.4.21.75).
paired basic amino acid cleaving enzyme inhibitor
paired basic amino acid cleaving enzyme inhibitors
paired basic amino acid converting enzyme inhibitor
paired basic amino acid converting enzyme inhibitors
substance with EC 3.4.21.75 (furin) inhibitor role
An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of dolichyl-phosphate-mannose-protein mannosyltransferase (EC 2.4.1.109).
EC 2.4.1.109 (dolichyl-phosphate-mannose-protein mannosyltransferase) inhibitors
dolichol phosphomannose-protein mannosyltransferase inhibitor
dolichol phosphomannose-protein mannosyltransferase inhibitors
dolichyl-D-mannosyl-phosphate:protein O-D-mannosyltransferase inhibitor
dolichyl-D-mannosyl-phosphate:protein O-D-mannosyltransferase inhibitors
dolichyl-phosphate-D-mannose:protein O-D-mannosyltransferase inhibitor
dolichyl-phosphate-D-mannose:protein O-D-mannosyltransferase inhibitors
dolichyl-phosphate-mannose--protein mannosyltransferase inhibitor
dolichyl-phosphate-mannose--protein mannosyltransferase inhibitors
protein O-D-mannosyltransferase inhibitor
protein O-D-mannosyltransferase inhibitors
substance with EC 2.4.1.109 (dolichyl-phosphate-mannose-protein mannosyltransferase) inhibitor role
An EC 3.4.23.* (aspartic endopeptidase) inhibitor that interferes with the activity of renin (EC 3.4.23.15).
substance with EC 3.4.23.15 (renin) inhibitor role
A chelator that is any compound containing a ligand (typically organic) which is able to form a bond to a central copper atom at two or more points.
An antagonist that binds to and deactivates neuropilin receptors.
substance with neuropilin receptor antagonist role
Any compound that exhibits antagonist activity at the kappa-opioid receptor.
substance with kappa-opioid receptor antagonist role
A substance which is poisonous to fish and is primarily used to eliminate dominant species of fish in water.
Any insecticide that is capable of killing egg cells.
Any inhibitor which inhibits the activity of cleavage and polyadenylation specificity factor subunit 3 protein (CPSF3).
cleavage and polyadenylation specific factor 3 inhibitor
cleavage and polyadenylation specific factor 3 inhibitors
cleavage and polyadenylation specificity factor 73 KDa subunit inhibitor
cleavage and polyadenylation specificity factor 73 KDa subunit inhibitors
cleavage and polyadenylation specificity factor subunit 3 inhibitor
cleavage and polyadenylation specificity factor subunit 3 inhibitors
An EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor that specifically inhibits the action of lysine-tRNA ligase (EC 6.1.1.6).
EC 6.1.1.6 (lysine--tRNA ligase) inhibitors
L-lysine:tRNA(Lys) ligase (AMP-forming) inhibitor
L-lysine:tRNA(Lys) ligase (AMP-forming) inhibitors
lysyl-transfer RNA synthetase inhibitors
lysyl-transfer ribonucleate synthetase inhibitor
lysyl-transfer ribonucleate synthetase inhibitors
substance with EC 6.1.1.6 (lysine--tRNA ligase) inhibitor role
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of Enhancer of zeste homolog 2 (EZH2), a histone-lysine N-methyltransferase (EC 2.1.1.43).
EC 2.1.1.43 (enhancer of zeste homolog 2) inhibitors
substance with EC 2.1.1.43 (enhancer of zeste homolog 2) inhibitor role
Any substance that inhibits the process of necroptosis (programmed form of necrosis) in organisms.
substance with necroptosis inhibitor role
A DNA polymerase inhibitor that interferes with the action of a RNA-directed RNA polymerase (EC 2.7.7.48).
EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitors
RNA nucleotidyltransferase (RNA-directed) inhibitor
RNA nucleotidyltransferase (RNA-directed) inhibitors
RNA-dependent ribonucleate nucleotidyltransferase inhibitor
RNA-dependent ribonucleate nucleotidyltransferase inhibitors
ribonucleic acid-dependent ribonucleate nucleotidyltransferase inhibitor
ribonucleic acid-dependent ribonucleate nucleotidyltransferase inhibitors
ribonucleic acid-dependent ribonucleic acid polymeras inhibitor
ribonucleic acid-dependent ribonucleic acid polymeras inhibitors
substance with EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor role
An antiparasitic agent which is effective against amoeba, a genus of single-celled amoeboids in the family Amoebidae.
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of mRNA m6A methyltransferase (EC 2.1.1.348).
EC 2.1.1.348 (mRNA m6A methyltransferase) inhibitors
substance with EC 2.1.1.348 (mRNA m6A methyltransferase) inhibitor role
An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of acetylornithine transaminase (EC 2.6.1.11).
2-N-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase inhibitor
2-N-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase inhibitors
EC 2.6.1.11 (acetylornithine transaminase) inhibitors
N(2)-acetyl-L-ornithine:2-oxoglutarate aminotransferase inhibitor
N(2)-acetyl-L-ornithine:2-oxoglutarate aminotransferase inhibitors
N(2)-acetylornithine 5-transaminase inhibitor
N(2)-acetylornithine 5-transaminase inhibitors
N-acetylornithine aminotransferase inhibitor
N-acetylornithine aminotransferase inhibitors
N-acetylornithine-delta-transaminase inhibitor
N-acetylornithine-delta-transaminase inhibitors
acetylornithine 5-aminotransferase inhibitor
acetylornithine 5-aminotransferase inhibitors
acetylornithine aminotransferase inhibitor
acetylornithine aminotransferase inhibitors
acetylornithine delta-transaminase inhibitor
acetylornithine delta-transaminase inhibitors
succinylornithine aminotransferase inhibitor
succinylornithine aminotransferase inhibitors
substance with EC 2.6.1.11 (acetylornithine transaminase) inhibitor role
An antimicrobial agent that is added to cosmetic formulations to maintain the microbiological safety of the products by inhibiting the growth of fungi or bacteria.
substance with antimicrobial cosmetic preservative role
Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.
substance with ferroptosis inhibitor role
Any substance that induces or promotes ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.
An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of inositol-phosphate phosphatase (EC 3.1.3.25).
EC 3.1.3.25 (inositol-phosphate phosphatase) inhibitors
L-myo-inositol-1-phosphate phosphatase inhibitor
L-myo-inositol-1-phosphate phosphatase inhibitors
inositol monophosphate phosphatase inhibitor
inositol monophosphate phosphatase inhibitors
inositol phosphate phosphatase inhibitor
inositol phosphate phosphatase inhibitors
inositol-1(or 4)-monophosphatase inhibitor
inositol-1(or 4)-monophosphatase inhibitors
inositol-phosphate phosphatase inhibitor
inositol-phosphate phosphatase inhibitors
myo-inositol-1(or 4)-monophosphatase inhibitor
myo-inositol-1(or 4)-monophosphatase inhibitors
myo-inositol-1(or 4)-phosphate phosphohydrolase inhibitor
myo-inositol-1(or 4)-phosphate phosphohydrolase inhibitors
substance with EC 3.1.3.25 (inositol-phosphate phosphatase) inhibitor role
Any agent that inhibits voltage-dependent anion channels.
voltage-dependent anion channel blockers
voltage-dependent anion channel inhibitors
voltage-dependent anion-selective channel blocker
voltage-dependent anion-selective channel blockers
voltage-dependent anion-selective channel inhibitor
voltage-dependent anion-selective channel inhibitors
substance with voltage-dependent anion channel inhibitor role
Any substance which inhibits thioredoxin, a group of small redox proteins.
substance with thioredoxin inhibitor role
A molecular entity that can undergo oxidation by the loss of hydrogen atom(s).
An inhibitor of peroxidases (EC 1.11.1.*) that inhibits the action of glutathione peroxidase (EC 1.11.1.9).
EC 1.11.1.9 (glutathione peroxidase) inhibitors
reduced glutathione peroxidase inhibitor
reduced glutathione peroxidase inhibitors
selenium-glutathione peroxidase inhibitor
selenium-glutathione peroxidase inhibitors
substance with EC 1.11.1.9 (glutathione peroxidase) inhibitor role
Any substance that induces the polymerisation of the protein actin.
substance with actin polymerisation inducer role
Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
An inhibitor which inhibits the action of ferroptosis suppressor protein 1.
apoptosis-inducing factor mitochondria-associated 2 inhibitor
apoptosis-inducing factor mitochondria-associated 2 inhibitors
ferroptosis suppressor protein 1 inhibitors
substance with ferroptosis suppressor protein 1 inhibitor role
A substance to which an electron may be transferred.
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of pyruvate dehydrogenase (acetyl-transferring) kinase (EC 2.7.11.2).
EC 2.7.11.2 - [pyruvate dehydrogenase (acetyl-transferring)] kinase inhibitors
[pyruvate dehydrogenase (acetyl-transferring)] kinase inhibitor
[pyruvate dehydrogenase (acetyl-transferring)] kinase inhibitors
pyruvate dehydrogenase (acetyl-transferring) kinase inhibitor
pyruvate dehydrogenase (acetyl-transferring) kinase inhibitors
pyruvate dehydrogenase kinase (phosphorylating) inhibitor
pyruvate dehydrogenase kinase (phosphorylating) inhibitors
pyruvate dehydrogenase kinase activator protein inhibitor
pyruvate dehydrogenase kinase activator protein inhibitors
pyruvate dehydrogenase kinase inhibitors
substance with EC 2.7.11.2 - [pyruvate dehydrogenase (acetyl-transferring)] kinase inhibitor role
An agonist that binds to and activates somatostatin receptors.
substance with somatostatin receptor agonist role
A molecular entity that can transfer ("donate") an electron, a pair of electrons, an atom or a group to another molecular entity.
A mainly tumour-specific antigen generated by mutations in tumour cells. Neoantigens are only expressed in tumour cells.
An EC 2.3.2.* (aminoacyltransferase) inhibitor that interferes with the action of beta-N-acetylhexosaminidase (EC 2.3.2.52).
EC 2.3.2.52 (beta-N-acetylhexosaminidase) inhibitors
N-acetyl-beta-D-hexosaminidase inhibitor
N-acetyl-beta-D-hexosaminidase inhibitors
beta-D-N-acetylhexosaminidase inhibitors
beta-N-acetyl-D-hexosaminidase inhibitor
beta-N-acetyl-D-hexosaminidase inhibitors
beta-acetylaminodeoxyhexosidase inhibitor
beta-acetylaminodeoxyhexosidase inhibitors
substance with EC 2.3.2.52 (beta-N-acetylhexosaminidase) inhibitor role
Any EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of trans-cinnamate 4-monooxygenase (EC 1.14.14.91).
EC 1.14.14.91 ( trans-cinnamate 4-monooxygenase) inhibitors
cinnamic acid 4-monooxygenase inhibitors
cytochrome P450 cinnamate 4-hydroxylase inhibitor
cytochrome P450 cinnamate 4-hydroxylase inhibitors
trans-cinnamate 4-hydroxylase inhibitors
trans-cinnamate 4-monooxygenase inhibitor
trans-cinnamate 4-monooxygenase inhibitors
trans-cinnamic acid 4-hydroxylase inhibitor
trans-cinnamic acid 4-hydroxylase inhibitors
substance with EC 1.14.14.91 ( trans-cinnamate 4-monooxygenase) inhibitor role
Any herbicide composed of urea or substituted urea substructure.
An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of kexin (EC 3.4.21.61).
Kex2-like precursor protein processing endoprotease inhibitor
Kex2-like precursor protein processing endoprotease inhibitors
andrenorphin-Gly-generating enzyme inhibitor
andrenorphin-Gly-generating enzyme inhibitors
prohormone-processing KEX2 proteinase inhibitor
prohormone-processing KEX2 proteinase inhibitors
prohormone-processing endoprotease inhibitor
prohormone-processing endoprotease inhibitors
prohormone-processing proteinase inhibitor
prohormone-processing proteinase inhibitors
substance with EC 3.4.21.61 (kexin) inhibitor role
a group of substances that bind to a receptor to change that receptor's response to stimulus.
substance with PAR2 negative allosteric modulator role
An antagonist at the protease-activated receptor-2.
G-protein coupled receptor 11 antagonist
G-protein coupled receptor 11 antagonists
coagulation factor II (thrombin) receptor-like 1 antagonist
coagulation factor II (thrombin) receptor-like 1 antagonists
protease-activated receptor 2 antagonist
protease-activated receptor 2 antagonists
protease-activated receptor-2 antagonists
substance with protease-activated receptor-2 antagonist role
Any receptor modulator acting on sigma receptors.
substance with sigma receptor modulator role
A sigma receptor modulator that activates the sigma-2 receptor.
substance with sigma-2 receptor agonist role
Any compound that mimics the activity of a ceramide, e.g. by inducing tumor cell death or suppression.
An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of alpha-mannosidase (EC 3.2.1.24).
EC 3.2.1.24 (alpha-mannosidase) inhibitors
p-nitrophenyl-alpha-mannosidase inhibitor
p-nitrophenyl-alpha-mannosidase inhibitors
substance with EC 3.2.1.24 (alpha-mannosidase) inhibitor role
A cannabinoid receptor agonist that binds to and activates type 1 cannabinoid receptors.
substance with CB1 receptor agonist role
A chemical or biochemical compound that is introduced in small concentrations to a living system to promote the biosynthesis of the target bioactive compound.
An EC 6.2.1.* (acid-thiol ligase) inhibitor that interferes with the action of E1 ubiquitin-activating enzyme (EC 6.2.1.45).
E1 ubiquitin-activating enzyme inhibitor
E1 ubiquitin-activating enzyme inhibitors
EC 6.2.1.45 (E1 ubiquitin-activating enzyme) inhibitors
ubiquitin-activating enzyme E1 inhibitor
ubiquitin-activating enzyme E1 inhibitors
substance with EC 6.2.1.45 (E1 ubiquitin-activating enzyme) inhibitor role
An agonist at the neurokinin-1 receptor.
substance with neurokinin-1 receptor agonist role
An agonist at the protease-activated receptor-1.
coagulation factor II (thrombin) receptor agonist
coagulation factor II (thrombin) receptor agonists
coagulation factor II thrombin receptor agonist
coagulation factor II thrombin receptor agonists
proteinase-activated receptor 1 agonists
substance with protease-activated receptor-1 agonist role
An agonist that binds to and activates piezo1 receptors.
piezo type mechanosensitive ion channel component 1 agonist
piezo type mechanosensitive ion channel component 1 agonists
piezo-type mechanosensitive ion channel component 1 agonist
piezo-type mechanosensitive ion channel component 1 agonists
Any inhibitor of mitochondrial calcium uniporter.
mitochondrial calcium uniporter blockers
mitochondrial calcium uniporter inhibitors
substance with mitochondrial calcium uniporter inhibitor role
An agonist that binds to and activates gastric inhibitory polypeptide (GIP) receptors.
gastric inhibitory polypeptide receptor agonists
glucose-dependent insulinotropic polypeptide receptor agonist
glucose-dependent insulinotropic polypeptide receptor agonists
substance with gastric inhibitory polypeptide receptor agonist role
Any agent that interferes with the activity of T-type calcium channels.
substance with T-type calcium channel blocker role
A class of diuretics which promote aquaresis (the excretion of water without electrolyte loss).
An agonist that activates NOD1 receptors.
caspase recruitment domain-containing protein 4 agonist
caspase recruitment domain-containing protein 4 agonists
nucleotide binding oligomerization domain containing 1 agonist
nucleotide binding oligomerization domain containing 1 agonists
nucleotide-binding oligomerization domain-containing protein 1 agonist
nucleotide-binding oligomerization domain-containing protein 1 agonists
A substance that increases the rate of a chemical reaction.
An activator of an enzyme-catalysed reaction.
An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of ornithine aminotransferase (EC 2.6.1.13).
EC 2.6.1.13 (ornithine aminotransferase) inhibitors
L-ornithine 5-aminotransferase inhibitor
L-ornithine 5-aminotransferase inhibitors
L-ornithine:alpha-ketoglutarate -aminotransferase inhibitor
L-ornithine:alpha-ketoglutarate -aminotransferase inhibitors
ornithine--oxo-acid transaminase inhibitor
ornithine--oxo-acid transaminase inhibitors
ornithine-2-oxoacid aminotransferase inhibitor
ornithine-2-oxoacid aminotransferase inhibitors
ornithine-alpha-ketoglutarate aminotransferase inhibitor
ornithine-alpha-ketoglutarate aminotransferase inhibitors
ornithine-keto acid aminotransferase inhibitor
ornithine-keto acid aminotransferase inhibitors
ornithine-keto acid transaminase inhibitor
ornithine-keto acid transaminase inhibitors
ornithine-ketoglutarate aminotransferase inhibitor
ornithine-ketoglutarate aminotransferase inhibitors
ornithine-oxo acid aminotransferase inhibitor
ornithine-oxo acid aminotransferase inhibitors
ornithine:alpha-oxoglutarate transaminase inhibitor
ornithine:alpha-oxoglutarate transaminase inhibitors
substance with EC 2.6.1.13 (ornithine aminotransferase) inhibitor role
Any inhibitor that acts on insulin-like growth factor-binding proteins.
insulin-like growth factor-binding protein inhibitors
substance with insulin-like growth factor-binding protein inhibitor role
An EC 2.7.12.* [dual-specificity kinases (those acting on Ser/Thr and Tyr residues)] inhibitor that inhibits the action of dual-specificity kinase (EC 2.7.12.1).
Arabidopsis dual specificity kinase 1 inhibitor
Arabidopsis dual specificity kinase 1 inhibitors
EC 2.7.12.1 (dual-specificity kinase) inhibitors
substance with EC 2.7.12.1 (dual-specificity kinase) inhibitor role
An inhibitor that interferes with the action of PCNA.
proliferating cell nuclear antigen inhibitor
proliferating cell nuclear antigen inhibitors
Any sphingosine-1-phosphate receptor (S1PR) antagonist that acts as an antagonist for the subtype 2 receptors (S1PR2).
sphingosine-1-phosphate receptor 2 antagonists
substance with sphingosine-1-phosphate receptor 2 antagonist role
An EC 3.5.3.* (non-peptide linear amidine C-N hydrolase) inhibitor that interferes with the action of arginase (EC 3.5.3.1).
substance with EC 3.5.3.1 (arginase) inhibitor role
An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amidine C-N hydrolase (EC 3.5.3.*).
EC 3.5.3.* (non-peptide linear amidine C-N hydrolase) inhibitors
non-peptide linear amidine C-N hydrolase (EC 3.5.3.*) inhibitor
non-peptide linear amidine C-N hydrolase (EC 3.5.3.*) inhibitors
substance with EC 3.5.3.* (non-peptide linear amidine C-N hydrolase) inhibitor role
An antagonist at any calcitonin gene-related peptide receptor.
calcitonin gene-related peptide receptor antagonists
substance with calcitonin gene-related peptide receptor antagonist role
Ras-related C3 botulinum toxin substrate 1 inhibitor
Ras-related C3 botulinum toxin substrate 1 inhibitors
A solvent used in nuclear magnetic resonance (NMR) spectroscopy.
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19).
3-enol-pyruvoylshikimate-5-phosphate synthase inhibitor
3-enol-pyruvoylshikimate-5-phosphate synthase inhibitors
3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) inhibitor
3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) inhibitors
3-phosphoshikimate 1-carboxyvinyltransferase inhibitor
3-phosphoshikimate 1-carboxyvinyltransferase inhibitors
5-enolpyruvylshikimate-3-phosphate synthase inhibitor
5-enolpyruvylshikimate-3-phosphate synthase inhibitors
EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitors
phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase inhibitor
phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase inhibitors
substance with EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitor role
A mitochondrial respiratory-chain inhibitor that interferes with the action of ATP synthase.
substance with ATP synthase inhibitor role
A substance used to destroy pests of the subclass Acari (mites and ticks).
An EC 2.2.1.* (transketolase/transaldolase) inhibitor that interferes with the action of acetolactate synthase (EC 2.2.1.6).
EC 2.2.1.6 (acetolactate synthase) inhibitors
acetolactate pyruvate-lyase (carboxylating) inhibitor
acetolactate pyruvate-lyase (carboxylating) inhibitors
acetolactate synthase (EC 2.2.1.6) inhibitor
acetolactate synthase (EC 2.2.1.6) inhibitors
alpha-acetohydroxy acid synthetase inhibitor
alpha-acetohydroxy acid synthetase inhibitors
alpha-acetohydroxyacid synthase inhibitor
alpha-acetohydroxyacid synthase inhibitors
alpha-acetolactate synthetase inhibitors
pyruvate:pyruvate acetaldehydetransferase (decarboxylating) inhibitor
pyruvate:pyruvate acetaldehydetransferase (decarboxylating) inhibitors
substance with EC 2.2.1.6 (acetolactate synthase) inhibitor role
substance with alicyclic antibiotics role
substance with aliphatic antibiotics role
Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases.
substance with alpha-1-microglobulin-Ig alpha complex chromophores role
substance with amino acid derivative antibiotics role
A substance that prevents pests from feeding.
A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
A substance that destroys or inhibits replication of viruses.
Any of a group of compounds, both naturally occurring and synthetic, that induce cell elongation in plant stems (from Greek alphaupsilonxialphanuomega, "to grow").
A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base).
substance with antinociceptive agent role
complement component 3a receptor 1 antagonist
complement component 3a receptor 1 antagonists
substance with C3a receptor antagonist role
A sigma receptor modulator that activates the sigma-1 receptor.
substance with sigma-1 receptor agonist role
beta-catenin - TCF interaction inhibitor
Benzoic acid, 2-phenoxy-, 2-[(5-methyl-2-furanyl)methylene]hydrazide
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of [histone H3]-lysine(4) N-trimethyltransferase (EC 2.1.1.354).
EC 2.1.1.354 ([histone H3]-lysine(4) N-trimethyltransferase) inhibitors
[histone H3]-lysine(4) N-trimethyltransferase inhibitor
[histone H3]-lysine(4) N-trimethyltransferase inhibitors
substance with EC 2.1.1.354 ([histone H3]-lysine(4) N-trimethyltransferase) inhibitor role
A substance that inhibits any of the WNK signalling pathway.
lysine deficient protein kinase (WNK) signaling inhibitor
lysine deficient protein kinase (WNK) signaling inhibitors
with no lysine [K] (WNK) pathway inhibitor
with no lysine [K] (WNK) pathway inhibitors
with-no-lysine (WNK) protein kinase signaling inhibitor
with-no-lysine (WNK) protein kinase signaling inhibitors
substance with WNK signaling inhibitor role
An agonist that selectively binds to and activates trace amine-associated receptor 1.
trace amine associated receptor 1 agonist
trace amine associated receptor 1 agonists
trace amine-associated receptor 1 agonists
substance with trace amine-associated receptor 1 agonist role
Any compound that produces a peak used as reference frequency in the delta chemical shift scale.
substance with NMR chemical shift reference compound role
Any inhibitor that interferes with the action of heat shock factor 1.
substance with heat shock factor 1 inhibitor role
An insecticide compound naturally occurring in plants.
substance with phytogenic insecticide role
Any inhibitor that interferes with the action of sodium-glucose transport protein subtype 1.
sodium glucose co-transporter 1 inhibitor
sodium glucose co-transporter 1 inhibitors
sodium-glucose transport protein subtype 1 inhibitors
sodium/glucose cotransporter 1 inhibitor
sodium/glucose cotransporter 1 inhibitors
solute carrier family 5 member 1 inhibitor
solute carrier family 5 member 1 inhibitors
substance with sodium-glucose transport protein subtype 1 inhibitor role
Any EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of phosphatidylinositol-4,5-bisphosphate 3-kinase (EC 2.7.1.153).
ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase inhibitor
ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase inhibitors
phosphatidylinositol-4,5-bisphosphate 3-kinase inhibitor
phosphatidylinositol-4,5-bisphosphate 3-kinase inhibitors
type I phosphoinositide 3-kinase inhibitor
type I phosphoinositide 3-kinase inhibitors
substance with EC 2.7.1.153 (phosphatidylinositol-4,5-bisphosphate 3-kinase) inhibitor role
substance with complement factor B inhibitor role
Any inhibitor of complement component 5.
substance with complement component 5 inhibitor role
An antagonist of the inhibitor of apoptosis proteins. Inhibitors of apoptosis proteins (IAP) are a family of functionally and structurally related proteins that serve as endogenous inhibitors of programmed cell death (apoptosis).
inhibitor of apoptosis protein antagonist
inhibitor of apoptosis protein antagonists
chromosomal region maintenance 1 inhibitor
chromosomal region maintenance 1 inhibitors
substance with exportin 1 inhibitor role
Any substance that inhibits the action of glucose transporters.
substance with glucose transporter inhibitor role
Any glucose transporter inhibitor that interferes with the action of glucose transporter 1.
solute carrier family 2, facilitated glucose transporter member 1 inhibitor
solute carrier family 2, facilitated glucose transporter member 1 inhibitors
substance with glucose transporter 1 inhibitor role
An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of carbonic anhydrase (EC 4.2.1.1). Such compounds reduce the secretion of H(+) ions by the proximal kidney tubule.
EC 4.2.1.1 (carbonic anhydrase) inhibitors
carbonate hydro-lyase (carbon-dioxide-forming) inhibitor
carbonate hydro-lyase (carbon-dioxide-forming) inhibitors
carbonic anhydrase (EC 4.2.1.1) inhibitor
carbonic anhydrase (EC 4.2.1.1) inhibitors
substance with EC 4.2.1.1 (carbonic anhydrase) inhibitor role
A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of 1,3-beta-glucan synthase (EC 2.4.1.34).
(1,3)-beta-glucan (callose) synthase inhibitor
(1,3)-beta-glucan (callose) synthase inhibitors
1,3-beta-D-glucan--UDP glucosyltransferase inhibitor
1,3-beta-D-glucan--UDP glucosyltransferase inhibitors
1,3-beta-D-glucan-UDP glucosyltransferase inhibitor
1,3-beta-D-glucan-UDP glucosyltransferase inhibitors
1,3-beta-glucan-uridine diphosphoglucosyltransferase inhibitor
1,3-beta-glucan-uridine diphosphoglucosyltransferase inhibitors
EC 2.4.1.34 (1,3-beta-glucan synthase) inhibitors
UDP-glucose--1,3-beta-D-glucan glucosyltransferase inhibitor
UDP-glucose--1,3-beta-D-glucan glucosyltransferase inhibitors
UDP-glucose-1,3-beta-D-glucan glucosyltransferase inhibitor
UDP-glucose-1,3-beta-D-glucan glucosyltransferase inhibitors
UDP-glucose-1,3-beta-glucan glucosyltransferase inhibitor
UDP-glucose-1,3-beta-glucan glucosyltransferase inhibitors
UDP-glucose-beta-glucan glucosyltransferase inhibitor
UDP-glucose-beta-glucan glucosyltransferase inhibitors
UDP-glucose:(1,3)beta-glucan synthase inhibitor
UDP-glucose:(1,3)beta-glucan synthase inhibitors
UDP-glucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase inhibitor
UDP-glucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase inhibitors
uridine diphosphoglucose-1,3-beta-glucan glucosyltransferase inhibitor
uridine diphosphoglucose-1,3-beta-glucan glucosyltransferase inhibitors
substance with EC 2.4.1.34 (1,3-beta-glucan synthase) inhibitor role
A substance intended to sterilize any organism.
substance with chitin synthesis inhibitor role
An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of nicotinamide phosphoribosyltransferase (EC 2.4.2.12).
EC 2.4.2.12 (nicotinamide phosphoribosyltransferase) inhibitor inhibitors
nicotinamide mononucleotide pyrophosphorylase inhibitor
nicotinamide mononucleotide pyrophosphorylase inhibitors
nicotinamide mononucleotide synthetase inhibitor
nicotinamide mononucleotide synthetase inhibitors
nicotinamide phosphoribosyltransferase inhibitor
nicotinamide phosphoribosyltransferase inhibitors
nicotinamide-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase inhibitor
nicotinamide-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase inhibitors
substance with EC 2.4.2.12 (nicotinamide phosphoribosyltransferase) inhibitor role
Bromo- and Extra-Terminal domain inhibitor
Bromo- and Extra-Terminal domain inhibitors
substance with BET bromodomain inhibitor role
interleukin 8 receptor, beta antagonists
An EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of fumarate reductase (NADH) (EC 1.3.1.6).
EC 1.3.1.6 (fumarate reductase (NADH)) inhibitors
NADH-dependent fumarate reductase inhibitor
NADH-dependent fumarate reductase inhibitors
substance with EC 1.3.1.6 (fumarate reductase (NADH)) inhibitor role
A drug that induces seizures or increases their severity.
Any compound that is able to prevent damage to the kidneys.
substance with renoprotective agent role
NACHT, LRR and PYD domains-containing protein 3 inhibitor
NACHT, LRR and PYD domains-containing protein 3 inhibitors
NLR family pyrin domain containing 3 inhibitor
NLR family pyrin domain containing 3 inhibitors
PYRIN-containing APAF1-like protein 1 inhibitor
PYRIN-containing APAF1-like protein 1 inhibitors
substance with desnitro-imidacloprid role
substance with heptacosa-7,11-diene role
1-cyclopropyl-6,8-difluoro-7-(4-hydroxyphenyl)-4-oxoquinoline-3-carboxylic acid
bathophenanthrolinedisulfonic acid disodium salt hydrate
substance with bathophenanthrolinedisulfonic acid disodium salt role
substance with benzoquinonium dibromide role
substance with methyllycaconitine citrate role
substance with 2-aminoethyl hydrogen sulfate role
substance with (2-hept-2-ynylsulfanylphenyl) acetate role
substance with 3,4,5-tri-O-galloylquinic acid role
substance with 3-aminopropyl(methyl)phosphinic acid role
cyclohexylmethyl-[(2S)-3-[[(1S)-1-(3,4-dichlorophenyl)ethyl]amino]-2-hydroxypropyl]phosphinic acid
substance with BIX-01294 trihydrochloride role
The part (atom or group of atoms) of a molecular entity in which the electronic transition responsible for a given spectral band is approximately localized.
substance with N-methyl-4-phenylpyridinium iodide role
substance with ammonium tetrathiomolybdate role
substance with 4-aminobenzhydrazide role
5-(5-(7-(Trifluoromethyl)quinolin-4-ylthio)pentyloxy)-2-(morpholinomethyl)-4H-pyran-4-one dihydrochloride
substance with EGTA acetoxymethyl ester role
A chelator that is any compound containing a ligand (typically organic) which is able to form a bond to a central calcium atom at two or more points.
Any product obtained as a result of mass spectrometer degradation.
substance with mass spectrometer degradation product role
A low-molecular-weight, non-protein organic compound participating in enzymatic reactions as dissociable acceptor or donor of chemical groups or electrons.
An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group).
substance with compatible osmolytes role
substance with cytochrome-b6f complex inhibitor role
A phytohormone that promote cell division, or cytokinesis, in plant roots and shoots.
A herbicide which when sprayed or dusted on plants causes its leaves to fall off.
Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances.
substance with ecdysone antagonists role
A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
Any vitamin that dissolves in fats and are stored in body tissues. Unlike the water-soluble vitamins, they are stored in the body for long periods of time and generally pose a greater risk for toxicity when consumed in excess.
substance with fat-soluble vitamin (role) role
A substance used to destroy fungal pests.
An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of glutamate--ammonia ligase (EC 6.3.1.2).
EC 6.3.1.2 (glutamate--ammonia ligase) inhibitors
L-glutamate:ammonia ligase (ADP-forming) inhibitor
L-glutamate:ammonia ligase (ADP-forming) inhibitors
glutamate--ammonia ligase (EC 6.3.1.2) inhibitor
glutamate--ammonia ligase (EC 6.3.1.2) inhibitors
glutamylhydroxamic synthetase inhibitors
substance with EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor role
substance with group transfer coenzymes role
A role played by the molecular entity or part thereof within a biological context.
A substance used to destroy plant pests.
Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
A growth regulator that inhibits the life cycle of an insect.
substance with insect growth regulator role
Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects.
A role played by a chemical agent which exhibits the capability of occupying space between DNA base pairs due to particular properties in size, shape and charge. Intercalation of chemical compounds in DNA helix can result in replication errors (shift, mutation) or DNA damages.
A compound which can carry specific ions through membranes of cells or organelles.
Any ionophore capable of transportation of iron ions across membranes.
The jasmonates (JAs) are a group of plant hormones which help regulate plant growth and development.
substance with juvenile hormone antagonists role
substance with juvenile hormone mimic role
A low-molecular-mass compound present in bioluminescent organisms that emits light when oxidized in presence of enzyme luciferase.
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
mitochondrial electron transport chain inhibitors
mitochondrial electron-transport chain inhibitor
mitochondrial respiratory chain inhibitors
substance with mitochondrial respiratory-chain inhibitor role
An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution.
A substance used to destroy pests of the phylum Nematoda (roundworms).
An endogenous compound that is used to transmit information across the synapse between a neuron and another cell.
A class of neuro-active insecticides that act at the nicotinic acetylcholine receptor.
substance with neonicotinoid insectide role
A role played by signal molecules produced by the symbiotic bacteria that trigger nodule formation (typically on the host plant roots).
substance with nucleoside antibiotic role
A solute used by a cell under water stress to maintain cell volume.
A substance that increases the efficacy of a pesticide.
Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.
A semiochemical used in olfactory communication between organisms of the same species eliciting a change in sexual or social behaviour.
substance with phosphorus containing antibiotics role
substance with photosynthetic electron-transport chain inhibitor role
substance with photosystem-I inhibitor role
substance with photosystem-II inhibitor role
A toxin made by a plant that acts against an organism attacking it.
An endogenous molecular entity that results in a colour of an organism as the consequence of the selective absorption of light.
A chemical, natural or artificial, that can affect the rate of growth of a plant.
substance with plant growth regulator role
substance with plant growth stimulator role
A tightly bound, specific nonpolypeptide unit in a protein determining and involved in its biological activity.
substance with pyrethroid insecticide role
A molecular messenger released by an organism that affects the behaviour within or between species.
Any of low-molecular-mass iron(III)-chelating compounds produced by microorganisms for the purpose of the transport and sequestration of iron.
A synthetic compound exhibiting auxin activity.
substance with systemic acquired resistance inducing compounds role
Poisonous substance produced by a biological organism such as a microbe, animal or plant.
Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions.
Any plant metabolite that is found naturally as a component of a volatile oil.
substance with volatile oil component role
Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine.
substance with water-soluble vitamin (role) role
substance with xenobiotic organic ethers role
A surfactant (or a mixture containing one or more surfactants) having cleaning properties in dilute solutions.
A biochemical role played by any micronutrient that is an organic compound. Vitamins are present in foods in small amounts and are essential to normal metabolism and biochemical functions, usually as coenzymes. The term "vitamines" (from vita + amines) was coined in 1912 by Casimir Funk, who believed that these compounds were amines.
A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis.
substance with antitubercular agent role
Intended use of the molecular entity or part thereof by humans.
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
A substance (or active part thereof) that kills or slows the growth of bacteria.
A nutrient is a food component that an organism uses to survive and grow.
An agrochemical is a substance that is used in agriculture or horticulture.
A fertilizer is any substance that is added to soil or water to assist the growth of plants.
A substance used to destroy rodent pests.
A substance used to destroy bird pests (class Aves).
A physiological role played by any substance of either plant, animal or artificial origin which contains essential body nutrients that can be ingested by an organism to provide energy, promote growth, and maintain the processes of life.
An energy-rich substance that can be transformed with release of usable energy.
A substance administered to aid diagnosis of a disease.
A substance used in a chemical reaction to detect, measure, examine, or produce other substances.
A substance used to destroy pests of the phylum Mollusca.
Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals.
A substance which lowers the surface tension of the medium in which it is dissolved, and/or the interfacial tension with other phases, and, accordingly, is positively adsorbed at the liquid/vapour and/or at other interfaces.
A part of a molecular entity (atom or group of atoms) in which electronic excitation associated with a given emission band is approximately localized.
A role played by a foreign substance mixed with or attached to a given substance to enable the distribution or location of the latter to be determined subsequently.
A role played by a chemical compound with properties similar to those of the substance being traced with which it is mixed homogeneously.
A tracer which only differs in isotopic composition from the substance to be traced.
A tracer containing a radioactive label.
A physical tracer is one that is attached by physical means to the object being traced.
A role played by a part of a molecular entity distinguishable by the observer but not by the system and used to identify a tracer.
A role played by a stable paramagnetic group that is attached to a part of a molecular entity whose microscopic environment is of interest and may be revealed by the electron spin resonance (ESR) spectroscopy.
substance with plant growth retardant role
A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization.
A substance that diminishes the rate of a chemical reaction.
A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction.
A small molecule which increases (activator) or decreases (inhibitor) the activity of an (allosteric) enzyme by binding to the enzyme at the regulatory site (which is different from the substrate-binding catalytic site).
Any substance or mixture of substances that, in solution (typically aqueous), resists change in pH upon addition of small amounts of acid or base.
A role played by a stable paramagnetic molecular entity used to study the microscopic environment by electron paramagnetic resonance (EPR) spectroscopy without covalent attachment to the molecular entity of interest.
A fuel such as coal, oil and natural gas which has formed over many years through the decomposition of deposited vegetation which was under extreme pressure of an overburden of earth.
Material containing fissile nuclides, which when placed in a reactor, enables a chain reaction to be achieved.
Any pharmaceutical compound containing a radioisotope.
Any drug that enhances the activity of the central nervous system.
substance with central nervous system stimulant role
A substance used in the prophylaxis or therapy of infectious diseases.
A substance used to treat or prevent parasitic infections.
Substance intended to kill parasitic worms (helminths).
A substance used in the treatment or control of nematode infestations.
An EC 3.4.15.* (peptidyl-dipeptidase) inhibitor that interferes with the action of peptidyl-dipeptidase A (EC 3.4.15.1).
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitors
angiotensin I-converting enzyme inhibitor
angiotensin I-converting enzyme inhibitors
angiotensin-converting enzyme inhibitors
dipeptidyl carboxypeptidase I inhibitors
endothelial cell peptidyl dipeptidase inhibitor
endothelial cell peptidyl dipeptidase inhibitors
peptidyl-dipeptidase A (EC 3.4.15.1) inhibitor
peptidyl-dipeptidase A (EC 3.4.15.1) inhibitors
substance with EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor role
Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system.
substance with central nervous system drug role
A loosely defined grouping of drugs that have effects on psychological function.
A substance that reduces or suppresses inflammation.
substance with anti-inflammatory drug role
A traditional grouping of drugs said to have a soothing or calming effect on mood, thought or behaviour.
Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
substance with non-steroidal anti-inflammatory drug role
Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
Antimanic drugs are agents used to treat bipolar disorders or mania associated with other affective disorders.
An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
substance with non-narcotic analgesic role
A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood.
An EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of aldehyde dehydrogenase (NAD(+)), EC 1.2.1.3.
CoA-independent aldehyde dehydrogenase inhibitor
CoA-independent aldehyde dehydrogenase inhibitors
EC 1.2.1.3 (aldehyde dehydrogenase (NAD(+))) inhibitor
EC 1.2.1.3 (aldehyde dehydrogenase (NAD(+))) inhibitors
EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitors
NAD-dependent 4-hydroxynonenal dehydrogenase inhibitor
NAD-dependent 4-hydroxynonenal dehydrogenase inhibitors
NAD-dependent aldehyde dehydrogenase inhibitor
NAD-dependent aldehyde dehydrogenase inhibitors
NAD-linked aldehyde dehydrogenase inhibitor
NAD-linked aldehyde dehydrogenase inhibitors
aldehyde dehydrogenase (NAD(+)) (EC 1.2.1.3) inhibitor
aldehyde dehydrogenase (NAD(+)) (EC 1.2.1.3) inhibitors
aldehyde dehydrogenase (NAD(+)) inhibitor
aldehyde dehydrogenase (NAD(+)) inhibitors
m-methylbenzaldehyde dehydrogenase inhibitor
m-methylbenzaldehyde dehydrogenase inhibitors
propionaldehyde dehydrogenase inhibitors
substance with EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor role
A loosely defined group of drugs that tend to reduce the activity of the central nervous system.
substance with central nervous system depressant role
A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.
A compound which inhibits or antagonises the biosynthesis or actions of androgens.
An agent that promotes the excretion of urine through its effects on kidney function.
Drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations and other alterations of mood and thinking.
An agent that selectively binds to and activates beta-adrenergic receptors.
substance with beta-adrenergic agonist role
An agent that causes an increase in the expansion of a bronchus or bronchial tubes.
substance with bronchodilator agent role
A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
substance with sympathomimetic agent role
A drug which lowers the blood glucose level.
An agent that binds to but does not activate beta-adrenergic receptors thereby blocking the actions of endogenous or exogenous beta-adrenergic agonists. beta-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
substance with beta-adrenergic antagonist role
A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes.
(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase inhibitor
(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase inhibitors
EC 1.14.99.1 (cyclooxygenase) inhibitors
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitors
cyclooxygenase (EC 1.14.99.1) inhibitors
prostaglandin endoperoxide synthetase inhibitor
prostaglandin endoperoxide synthetase inhibitors
substance with EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor role
A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
An agent that selectively binds to and activates alpha-adrenergic receptors.
substance with alpha-adrenergic agonist role
An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor which interferes with the activity of the enzyme protein tyrosine phosphatases (PTPs), EC 3.1.3.48, involved in the removal of phosphate groups from phosphorylated tyrosine residues on proteins.
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitors
[phosphotyrosine]protein phosphatase inhibitor
[phosphotyrosine]protein phosphatase inhibitors
phosphoprotein phosphatase (phosphotyrosine) inhibitor
phosphoprotein phosphatase (phosphotyrosine) inhibitors
phosphotyrosine histone phosphatase inhibitor
phosphotyrosine histone phosphatase inhibitors
phosphotyrosine protein phosphatase inhibitor
phosphotyrosine protein phosphatase inhibitors
phosphotyrosylprotein phosphatase inhibitor
phosphotyrosylprotein phosphatase inhibitors
protein phosphotyrosine phosphatase inhibitor
protein phosphotyrosine phosphatase inhibitors
protein-tyrosine-phosphatase (EC 3.1.3.48) inhibitor
protein-tyrosine-phosphatase (EC 3.1.3.48) inhibitors
protein-tyrosine-phosphate phosphohydrolase inhibitor
protein-tyrosine-phosphate phosphohydrolase inhibitors
tyrosine O-phosphate phosphatase inhibitor
tyrosine O-phosphate phosphatase inhibitors
substance with EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor role
A substance that inhibits or prevents the proliferation of neoplasms.
substance with antineoplastic agent role
A food additive that is used to added improve the taste or odour of a food.
A drug used to cause dilation of the blood vessels.
A drug used to prevent seizures or reduce their severity.
An EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor that interferes with the action of beta-lactamase (EC 3.5.2.6).
penicillin amido-beta-lactamhydrolase inhibitor
penicillin amido-beta-lactamhydrolase inhibitors
substance with EC 3.5.2.6 (beta-lactamase) inhibitor role
An EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitor that interferes with the action of xanthine oxidase (EC 1.17.3.2).
EC 1.17.3.2 (xanthine oxidase) inhibitors
hypoxanthine-xanthine oxidase inhibitors
hypoxanthine:oxygen oxidoreductase inhibitor
hypoxanthine:oxygen oxidoreductase inhibitors
xanthine oxidase (EC 1.17.3.2) inhibitor
xanthine oxidase (EC 1.17.3.2) inhibitors
xanthine:oxygen oxidoreductase inhibitor
xanthine:oxygen oxidoreductase inhibitors
substance with EC 1.17.3.2 (xanthine oxidase) inhibitor role
Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
substance with adrenergic uptake inhibitor role
An inhibitor of HIV protease, an enzyme required for production of proteins needed for viral assembly.
substance with HIV protease inhibitor role
Any EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. The Enzyme Commission designation is EC 1.1.1.34 for the NADPH-dependent enzyme and EC 1.1.1.88 for an NADH-dependent enzyme.
hydroxymethylglutaryl-CoA reductase inhibitor
hydroxymethylglutaryl-CoA reductase inhibitors
substance with EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor role
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
substance with antihypertensive agent role
A drug that binds to and activates histamine receptors. Although they have been suggested for a variety of clinical applications, histamine agonists have so far been more widely used in research than therapeutically.
A substance used to treat hyperlipidemia (an excess of lipids in the blood).
An agent used to treat cestode, trematode, or other flatworm infestations in man or animals.
substance with antiplatyhelmintic drug role
A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
substance with immunosuppressive agent role
A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
A substance that suppresses Mycobacterium leprae, ameliorates the clinical manifestations of leprosy, and/or reduces the incidence and severity of leprous reactions.
An agent useful in the treatment or prevention of coccidiosis in man or animals.
Any antimicrobial drug which is used to treat or prevent protozoal infections.
A substance used to lower plasma cholesterol levels.
substance with anticholesteremic drug role
A gout suppressant that acts directly on the renal tubule to increase the excretion of uric acid, thus reducing its concentrations in plasma.
A drug used to treat rheumatoid arthritis.
A drug that increases uric acid excretion by the kidney (uricosuric drug), decreases uric acid production (antihyperuricemic), or alleviates the pain and inflammation of acute attacks of gout.
A drug used for its effect on the kidneys' regulation of body fluid composition and volume.
A compound or agent that combines with lipoxygenase and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of the icosanoid products hydroxyicosatetraenoic acid and various leukotrienes.
substance with lipoxygenase inhibitor role
An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
substance with serotonergic agonist role
A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.
substance with neurotransmitter agent role
A drug used to treat or prevent microbial infections.
A substance used in the prophylaxis or therapy of virus diseases.
A drug used to treat or prevent bacterial infections.
A drug used in the treatment of infections with bacteria of the genus Treponema.
A substance that is used in the treatment of syphilis.
A drug used to treat infestations with arthropods of the subclass Acari (mites and ticks).
A drug that stimulates contraction of the myometrium. Oxytocics are used to induce labour, obstetric at term, to prevent or control postpartum or postabortion haemorrhage, and to assess foetal status in high risk pregnancies. They may also be used alone or with other drugs to induce abortions (abortifacients).
Any member of a group of drugs that reversibly inhibit the propagation of signals along nerves. Wide variations in potency, stability, toxicity, water-solubility and duration of action determine the route used for administration, e.g. topical, intravenous, epidural or spinal block.
A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida.
A compound which stimulates anabolism and inhibits catabolism. Anabolic agents stimulate the development of muscle mass, strength, and power.
An agent that promotes the production and release of interferons.
Any EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of phosphoprotein phosphatase (EC 3.1.3.16).
3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase inhibitor
3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase inhibitors
Aspergillus awamori acid protein phosphatase inhibitor
Aspergillus awamori acid protein phosphatase inhibitors
EC 3.1.3.16 (protein serine/threonine phosphatase) inhibitors
HMG-CoA reductase phosphatase inhibitors
branched-chain alpha-keto acid dehydrogenase phosphatase inhibitor
branched-chain alpha-keto acid dehydrogenase phosphatase inhibitors
phosphoprotein phosphatase (EC 3.1.3.16) inhibitor
phosphoprotein phosphatase (EC 3.1.3.16) inhibitors
phosphoprotein phosphohydrolase inhibitor
phosphoprotein phosphohydrolase inhibitors
phosphopyruvate dehydrogenase phosphatase inhibitor
phosphopyruvate dehydrogenase phosphatase inhibitors
polycation modulated (PCM-) phosphatase inhibitor
polycation modulated (PCM-) phosphatase inhibitors
protein serine/threonine phosphatase (EC 3.1.3.16) inhibitors
protein serine/threonine phosphatase inhibitor
protein serine/threonine phosphatase inhibitors
serine/threonine specific protein phosphatase inhibitor
serine/threonine specific protein phosphatase inhibitors
substance with EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor role
A substance administered to enhance contrast in images of the inside of the body obtained using X-rays, gamma-rays, sound waves, radio waves (MRI), or radioactive particles in order to diagnose disease.
substance with diagnostic imaging agent role
substance with radioactive imaging agent role
substance with ultrasound contrast agent role
A substance having the property of absorbing, and therefore being opaque to, electromagnetic radiation, particularly X-rays.
An EC 2.7.7.* (nucleotidyltransferase) inhibitor that interferes with the action of RNA polymerase (EC 2.7.7.6).
C ribonucleic acid formation factors inhibitor
C ribonucleic acid formation factors inhibitors
DNA-dependent RNA nucleotidyltransferase inhibitor
DNA-dependent RNA nucleotidyltransferase inhibitors
DNA-dependent ribonucleate nucleotidyltransferase inhibitor
DNA-dependent ribonucleate nucleotidyltransferase inhibitors
DNA-directed nucleoside-triphosphate:RNA nucleotidyltransferase inhibitor
DNA-directed nucleoside-triphosphate:RNA nucleotidyltransferase inhibitors
RNA nucleotidyltransferase (DNA-directed) inhibitor
RNA nucleotidyltransferase (DNA-directed) inhibitors
deoxyribonucleic acid-dependent ribonucleic acid polymerase inhibitor
deoxyribonucleic acid-dependent ribonucleic acid polymerase inhibitors
nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) inhibitor
nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) inhibitors
ribonucleate nucleotidyltransferase inhibitor
ribonucleate nucleotidyltransferase inhibitors
ribonucleic acid nucleotidyltransferase inhibitor
ribonucleic acid nucleotidyltransferase inhibitors
ribonucleic acid transcriptase inhibitor
ribonucleic acid transcriptase inhibitors
substance with EC 2.7.7.6 (RNA polymerase) inhibitor role
An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid).
A compound which inhibits or antagonizes the biosynthesis or actions of proteases (endopeptidases).
An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases.
substance with protein kinase inhibitor role
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of protein kinase C (EC 2.7.11.13).
ATP:protein phosphotransferase (diacylglycerol-dependent) inhibitor
ATP:protein phosphotransferase (diacylglycerol-dependent) inhibitors
EC 2.7.11.13 (protein kinase C) inhibitors
calcium-dependent protein kinase C inhibitor
calcium-dependent protein kinase C inhibitors
calcium-independent protein kinase C inhibitor
calcium-independent protein kinase C inhibitors
calcium/phospholipid dependent protein kinase inhibitor
calcium/phospholipid dependent protein kinase inhibitors
protein kinase C (EC 2.7.11.13) inhibitor
protein kinase C (EC 2.7.11.13) inhibitors
substance with EC 2.7.11.13 (protein kinase C) inhibitor role
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8).
choline esterase II (unspecific) inhibitor
choline esterase II (unspecific) inhibitors
substance with EC 3.1.1.8 (cholinesterase) inhibitor role
A hormone that specifically regulates growth.
A plant growth regulator that modulates the formation of stems, leaves and flowers, as well as the development and ripening of fruit. The term includes endogenous and non-endogenous compounds (e.g. active compounds produced by bacteria on the leaf surface) as well as semi-synthetic and fully synthetic compounds.
An agent that selectively binds to and activates adrenergic receptors.
An agent that binds to but does not activate adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists.
substance with adrenergic antagonist role
An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
substance with alpha-adrenergic antagonist role
substance with phenothiazine antipsychotic drug role
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
substance with H1-receptor antagonist role
Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
substance with histamine antagonist role
Drugs used for their actions on histaminergic systems.
H2-receptor antagonists are the drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of endogenous histamine.
substance with H2-receptor antagonist role
Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter.
substance with triazine insecticide role
A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
substance with anti-arrhythmia drug role
A drug that has a strengthening effect on the heart or that can increase cardiac output.
Any of low-molecular-mass iron(III)-chelating compounds produced by plants for the purpose of the transport and sequestration of iron.
A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate.
One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools.
substance with calcium channel blocker role
substance with DNA polymerase inhibitor role
An EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 atoms of oxygen) inhibitor that interferes with the activity of 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27).
4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) inhibitor
4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) inhibitors
4-hydroxyphenylpyruvate dioxygenase inhibitor
4-hydroxyphenylpyruvate dioxygenase inhibitors
4-hydroxyphenylpyruvate hydroxylase inhibitor
4-hydroxyphenylpyruvate hydroxylase inhibitors
4-hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating, decarboxylating) inhibitor
4-hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating, decarboxylating) inhibitors
4-hydroxyphenylpyruvic acid dioxygenase inhibitor
4-hydroxyphenylpyruvic acid dioxygenase inhibitors
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitors
p-hydroxyphenylpyruvate dioxygenase inhibitor
p-hydroxyphenylpyruvate dioxygenase inhibitors
p-hydroxyphenylpyruvate hydroxylase inhibitor
p-hydroxyphenylpyruvate hydroxylase inhibitors
p-hydroxyphenylpyruvate oxidase inhibitor
p-hydroxyphenylpyruvate oxidase inhibitors
p-hydroxyphenylpyruvic acid hydroxylase inhibitor
p-hydroxyphenylpyruvic acid hydroxylase inhibitors
p-hydroxyphenylpyruvic hydroxylase inhibitor
p-hydroxyphenylpyruvic hydroxylase inhibitors
p-hydroxyphenylpyruvic oxidase inhibitor
p-hydroxyphenylpyruvic oxidase inhibitors
substance with EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor role
Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons.
Any drug that binds to and activates cholinergic receptors.
Any drug that binds to and activates a muscarinic cholinergic receptor.
muscarinic acetylcholine receptor agonist
Derivatives of carbamic acid with insecticidal properties of general formula ROC(=O)NR(1)R(2), where ROH is an alcohol, oxime, or phenol and R(1) is hydrogen or methyl. Like organophosphate insecticides, they are cholinesterase inhibitors, but carbamate insecticides differ in action from the organophosphates in that the inhibitory effect on cholinesterase is generally brief.
substance with carbamate insecticide role
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid.
EC 3.1.1.7 (acetylcholinesterase) inhibitors
acetyl.beta-methylcholinesterase inhibitor
acetyl.beta-methylcholinesterase inhibitors
acetylcholine acetylhydrolase inhibitors
acetylcholinesterase (EC 3.1.1.7) inhibitor
acetylcholinesterase (EC 3.1.1.7) inhibitors
substance with EC 3.1.1.7 (acetylcholinesterase) inhibitor role
substance with electron-transport chain inhibitor role
substance with respiratory-chain inhibitor role
mitochondrial NADH dehydrogenase inhibitor
substance with mitochondrial NADH:ubiquinone reductase inhibitor role
substance with mitochondrial cytochrome-bc1 complex inhibitor role
An EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor that interferes with the action of cytochrome c oxidase (EC 1.9.3.1).
EC 1.9.3.1 (cytochrome c oxidase) inhibitors
complex IV (mitochondrial electron transport) inhibitor
complex IV (mitochondrial electron transport) inhibitors
cytochrome c oxidase (EC 1.9.3.1) inhibitor
cytochrome c oxidase (EC 1.9.3.1) inhibitors
ferrocytochrome-c:oxygen oxidoreductase inhibitor
ferrocytochrome-c:oxygen oxidoreductase inhibitors
mitochondrial cytochrome-c oxidase inhibitors
substance with EC 1.9.3.1 (cytochrome c oxidase) inhibitor role
substance with cytochrome-bc1 complex inhibitor role
A respiratory-chain inhibitor that interferes with the action of the the enzyme NADH:ubiquinone reductase (H(+)-translocating), EC 1.6.5.3.
EC 1.6.5.3 (NADH:ubiquinone reductase (H(+)-translocating)) inhibitor
EC 1.6.5.3 (NADH:ubiquinone reductase (H(+)-translocating)) inhibitors
EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitors
NADH dehydrogenase (ubiquinone) inhibitor
NADH dehydrogenase (ubiquinone) inhibitors
NADH-coenzyme Q oxidoreductase inhibitors
NADH-ubiquinone oxidoreductase inhibitor
NADH-ubiquinone oxidoreductase inhibitors
NADH2 dehydrogenase (ubiquinone) inhibitor
NADH:ubiquinone oxidoreductase complex inhibitor
NADH:ubiquinone oxidoreductase inhibitor
NADH:ubiquinone oxidoreductase inhibitors
NADH:ubiquinone reductase (H(+)-translocating) inhibitor
NADH:ubiquinone reductase (H(+)-translocating) inhibitors
NADH:ubiquinone reductase (H+-translocating) inhibitor
complex I (NADH:Q1 oxidoreductase) inhibitors
complex I (electron transport chain) inhibitors
complex I (mitochondrial electron transport) inhibitors
dihydronicotinamide adenine dinucleotide-coenzyme Q reductase inhibitor
mitochondrial electron transport complex 1 inhibitor
mitochondrial electron transport complex I inhibitor
mitochondrial electron transport complex I inhibitors
reduced nicotinamide adenine dinucleotide-coenzyme Q reductase inhibitor
reduced nicotinamide adenine dinucleotide-coenzyme Q reductase inhibitors
substance with EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor role
An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of monoamine oxidase (EC 1.4.3.4).
EC 1.4.3.4 (monoamine oxidase) inhibitors
amine oxidase (flavin-containing) inhibitor
amine oxidase (flavin-containing) inhibitors
amine:oxygen oxidoreductase (deaminating) (flavin-containing) inhibitor
amine:oxygen oxidoreductase (deaminating) (flavin-containing) inhibitors
amine:oxygen oxidoreductase (deaminating) inhibitor
amine:oxygen oxidoreductase (deaminating) inhibitors
monoamine oxidase (EC 1.4.3.4) inhibitor
monoamine oxidase (EC 1.4.3.4) inhibitors
monoamine:O2 oxidoreductase (deaminating) inhibitor
monoamine:O2 oxidoreductase (deaminating) inhibitors
substance with EC 1.4.3.4 (monoamine oxidase) inhibitor role
Any agent that affects the transport of molecular entities across a biological membrane.
substance with membrane transport modulator role
An agent that inhibits sodium influx through cell membranes.
substance with sodium channel blocker role
Any sodium channel blocker that interferes with the activity of voltage-gated sodium channels.
voltage-dependent sodium channel blockers
substance with voltage-gated sodium channel blocker role
Any protein kinase inhibitor that interferes with the action of tyrosine kinase.
substance with tyrosine kinase inhibitor role
Substance used to treat lice (genus Pediculus) infestation.
Agents that increase calcium influx into calcium channels of excitable tissues.
substance with calcium channel agonist role
A membrane transport modulator that is able to regulate intracellular calcium levels.
substance with calcium channel modulator role
ryanodine-sensitive calcium channel modulator
ryanodine-sensitive calcium-release channel modulator
substance with ryanodine receptor modulator role
A surfactant with an uncharged hydrophilic headgroup.
A substance that can carry oxygen to and carbon dioxide away from the tissues when introduced into the blood stream. Blood substitutes are used to replace hemoglobin in severe hemorrhage and also to perfuse isolated organs.
Substance which produces loss of feeling or sensation.
Substance that produces loss of consciousness.
substance with inhalation anaesthetic role
substance with intravenous anaesthetic role
Drugs that used to treat infestations by flukes (trematodes) of the genus Schistosoma.
substance with schistosomicide drug role
substance with GABA-gated chloride channel antagonist role
substance with sodium channel modulator role
Any member of a collection of zwitterionic buffer substances selected or devised for suitability in experimental biological systems according to a number of predetermined criteria. Named after Dr. Norman Good.
substance with Good's buffer substance role
substance with pyrethroid ester insecticide role
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
A molecular entity that is an electron-pair acceptor and therefore able to form a covalent bond with an electron-pair donor (Lewis base), thereby producing a Lewis adduct.
A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct.
substance with antibiotic insecticide role
substance with antibiotic pesticide role
substance with antibiotic acaricide role
substance with antibiotic nematicide role
substance with pyrethroid ester acaricide role
A volatile or volatilizable chemical compound utilized for control of pests in buildings, soil, grain, as well as during processing of goods to be imported or exported to prevent transfer of exotic organisms.
substance with fumigant insecticide role
substance with sulfite ester acaricide role
substance with mite growth regulator role
Any chemical substance that inhibits the life-cycle of an organism.
substance with pyrethroid ether insecticide role
substance with pyrethroid ether acaricide role
substance with homopteran inhibitor of chitin biosynthesis role
substance with lepidopteran inhibitor of chitin biosynthesis role
substance with bridged diphenyl acaricide role
substance with dinitrophenol insecticide role
A role played by a fluorescent molecular entity used to study the microscopic environment by fluorescence spectroscopy.
Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye.
A liquid that can dissolve other substances (solutes) without any change in their chemical composition.
Anything used in a scientific experiment to indicate the presence of a substance or quality, change in a body, etc.
A chemical compound that can be excited by light of a specific wavelength and subsequently transfer energy to a chosen reactant. This is commonly molecular oxygen within a cancer tissue, which is converted to (highly rective) singlet state oxygen. This rapidly reacts with any nearby biomolecules, ultimately killing the cancer cells.
substance with photosensitizing agent role
An agonist that selectively binds to and activates a nicotinic acetylcholine receptor.
nicotinic acetylcholine receptor agonists
substance with nicotinic acetylcholine receptor agonist role
A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein.
substance with protein synthesis inhibitor role
A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body).
An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity.
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
substance with serotonergic antagonist role
A substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell.
An exogenous or endogenous compound which inhibits serine endopeptidases.
substance with serine proteinase inhibitor role
A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds.
A polar solvent that is capable of acting as a hydron (proton) donor.
A solvent with a comparatively high relative permittivity (or dielectric constant), greater than ca. 15, and a sizable permanent dipole moment, that cannot donate suitably labile hydrogen atoms to form strong hydrogen bonds.
substance with polar aprotic solvent role
Solvent that is capable of acting as a hydron (proton) acceptor.
Self-ionizing solvent possessing both characteristics of Bronsted acids and bases.
An EC 2.1.1.* (methyltransferase) inhibitor that interferes with the action of catechol O-methyltransferase (EC 2.1.1.6).
EC 2.1.1.6 (catechol O-methyltransferase) inhibitors
S-adenosyl-L-methionine:catechol O-methyltransferase inhibitor
S-adenosyl-L-methionine:catechol O-methyltransferase inhibitors
catechol O-methyltransferase (EC 2.1.1.6) inhibitor
catechol O-methyltransferase (EC 2.1.1.6) inhibitors
catecholamine O-methyltransferase inhibitor
catecholamine O-methyltransferase inhibitors
substance with EC 2.1.1.6 (catechol O-methyltransferase) inhibitor role
A drug used in the treatment of Parkinson's disease.
An agent and endogenous substances that antagonize or inhibit the development of new blood vessels.
substance with angiogenesis inhibitor role
A local anesthetic that is used to numb the surface of a body part.
A drug that it mimics the action of calcium on tissues.
Any drug that acts on an alpha-adrenergic receptor.
substance with alpha-adrenergic drug role
Any of the drugs that act on beta-adrenergic receptors.
substance with beta-adrenergic drug role
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of aldehyde reductase (EC 1.1.1.21).
EC 1.1.1.21 (aldehyde reductase) inhibitors
aldehyde reductase (EC 1.1.1.21) inhibitor
aldehyde reductase (EC 1.1.1.21) inhibitors
alditol:NAD(P)(+) 1-oxidoreductase inhibitor
alditol:NAD(P)(+) 1-oxidoreductase inhibitors
alditol:NADP(+) 1-oxidoreductase inhibitor
alditol:NADP(+) 1-oxidoreductase inhibitors
polyol dehydrogenase (NADP(+)) inhibitor
polyol dehydrogenase (NADP(+)) inhibitors
substance with EC 1.1.1.21 (aldehyde reductase) inhibitor role
A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons.
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
substance with dopaminergic antagonist role
A role played by a substance that can react readily with, and thereby eliminate, radicals.
A modulator of gamma-secretase, one of the three endopeptidases that are specific for amyloid protein precursor and which have been identified based upon the region of the amyloid protein precursor which they cleave.
substance with gamma-secretase modulator role
A drug that prevent fibrinolysis or lysis of a blood clot or thrombus.
substance with antifibrinolytic drug role
A drug that affects the function of fibrin in blood coagulation.
substance with fibrin modulating drug role
Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own.
Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances.
Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.
substance with cholinergic antagonist role
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
muscarinic acetylcholine receptor antagonist
substance with muscarinic antagonist role
An antagonist at the nicotinic cholinergic receptor.
nicotinic acetylcholine receptor antagonist
nicotinic acetylcholine receptor antagonists
substance with nicotinic antagonist role
Metabolites of bile acids, four-ringed steroid acids formed along the cholesterol degradation pathway.
substance with bile acid metabolite role
A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.
A compound that inhibits the action of prostaglandins.
substance with prostaglandin antagonist role
A drug that acts principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system.
substance with peripheral nervous system drug role
A drug designed to prevent leukotriene synthesis or activity by blocking binding at the receptor level.
substance with leukotriene antagonist role
An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that inhibits H(+)/K(+)-exchanging ATPase, EC 3.6.3.10. Such compounds are also known as proton pump inhibitors.
ATP phosphohydrolase (H(+)/K(+)-exchanging) inhibitor
ATP phosphohydrolase (H(+)/K(+)-exchanging) inhibitors
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitors
substance with EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor role
One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract.
Any inhibitor of cholesterylester transfer protein (CETP), which transfers cholesterol from high density lipoproteins (HDL, the 'good' cholesterol-containing particles) to low or very low density lipoproteins (LDL or VLDL, the 'bad' cholesterol-containing particles). Inhibition of this process results in higher HDL levels and lower LDL levels. CETP inhibitors are under investigation as potential drugs to reduce the risk of arteriosclerotic vascular disease (atherosclerosis).
cholesteryl ester transfer protein inhibitor
A chemical substance that prevents or reduces the probability of conception.
A chemical substance or agent with contraceptive activity in females.
substance with female contraceptive drug role
A compound, usually hormonal, taken orally in order to block ovulation and prevent the occurrence of pregnancy.
An oral contraceptive which owes its effectiveness to synthetic preparation.
substance with synthetic oral contraceptive role
An agent that binds to and activates excitatory amino acid receptors.
substance with excitatory amino acid agonist role
Any hormone that is responsible for controlling sexual characteristics and reproductive function.
A sex hormone that stimulates or controls the development and maintenance of masculine characteristics in vertebrates by binding to androgen receptors.
A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens.
Any compound that exhibits antagonist activity at the mu-opioid receptor
substance with mu-opioid receptor antagonist role
A drug which causes a narrowing of the lumen of a bronchus or bronchiole.
substance with bronchoconstrictor agent role
A drug that softens, separates, and causes desquamation of the cornified epithelium or horny layer of skin. Keratolytic drugs are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases.
A drug used to treat or prevent skin disorders or for the routine care of skin.
An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances.
A compound which inhibits the movement of an ion across an energy-transducing cell membrane.
substance with ion transport inhibitor role
Any pathway inhibitor that inhibits the synthesis of fatty acids.
substance with fatty acid synthesis inhibitor role
A substance that can be converted into a vitamin by animal tissues.
An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a phosphoric diester hydrolase (EC 3.1.4.*).
EC 3.1.4.* (phosphoric diester hydrolase) inhibitors
phosphoric diester hydrolase (EC 3.1.4.*) inhibitor
phosphoric diester hydrolase (EC 3.1.4.*) inhibitors
substance with EC 3.1.4.* (phosphoric diester hydrolase) inhibitor role
A drug used to reverse the inactivation of cholinesterase caused by organophosphates or sulfonates.
substance with cholinesterase reactivator role
Compound which restore enzymatic activity by removing an inhibitory group bound to the reactive site of the enzyme.
Any protective agent counteracting or neutralizing the action of poisons.
Drug that acts on blood and blood-forming organs and those that affect the hemostatic system.
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent.
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of alcohol dehydrogenase (EC 1.1.1.1).
EC 1.1.1.1 (alcohol dehydrogenase) inhibitors
NAD-dependent alcohol dehydrogenase inhibitor
NAD-dependent alcohol dehydrogenase inhibitors
NAD-specific aromatic alcohol dehydrogenase inhibitor
NAD-specific aromatic alcohol dehydrogenase inhibitors
alcohol dehydrogenase (EC 1.1.1.1) inhibitor
alcohol dehydrogenase (EC 1.1.1.1) inhibitors
aliphatic alcohol dehydrogenase inhibitor
aliphatic alcohol dehydrogenase inhibitors
primary alcohol dehydrogenase inhibitors
substance with EC 1.1.1.1 (alcohol dehydrogenase) inhibitor role
A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC 5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA.
EC 5.99.1.2 (DNA topoisomerase) inhibitors
EC 5.99.1.2 (topoisomerase I) inhibitors
topoisomerase I (EC 5.99.1.2) inhibitors
substance with EC 5.99.1.2 (DNA topoisomerase) inhibitor role
Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists.
An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the activity of ceramide glucosyltransferase (EC 2.4.1.80).
EC 2.4.1.80 (ceramide glucosyltransferase) inhibitors
UDP-glucose:N-acylsphingosine D-glucosyltransferase inhibitor
UDP-glucose:N-acylsphingosine D-glucosyltransferase inhibitors
UDP-glucose:ceramide glucosyltransferase inhibitor
UDP-glucose:ceramide glucosyltransferase inhibitors
ceramide glucosyltransferase (EC 2.4.1.80) inhibitor
ceramide glucosyltransferase (EC 2.4.1.80) inhibitors
ceramide:UDP-glucose glucosyltransferase inhibitor
ceramide:UDP-glucose glucosyltransferase inhibitors
ceramide:UDPGlc glucosyltransferase inhibitor
ceramide:UDPGlc glucosyltransferase inhibitors
uridine diphosphoglucose-ceramide glucosyltransferase inhibitor
uridine diphosphoglucose-ceramide glucosyltransferase inhibitors
substance with EC 2.4.1.80 (ceramide glucosyltransferase) inhibitor role
An EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor that interferes with the action of NAD(P)H dehydrogenase (quinone), EC 1.6.5.2.
EC 1.6.5.2 (NAD(P)H dehydrogenase (quinone)) inhibitor
EC 1.6.5.2 (NAD(P)H dehydrogenase (quinone)) inhibitors
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitors
NAD(P)H dehydrogenase (quinone) (EC 1.6.5.2) inhibitor
NAD(P)H dehydrogenase (quinone) (EC 1.6.5.2) inhibitors
NAD(P)H dehydrogenase (quinone) inhibitor
NAD(P)H dehydrogenase (quinone) inhibitors
NAD(P)H-quinone dehydrogenase inhibitors
NAD(P)H-quinone oxidoreductase inhibitor
NAD(P)H-quinone oxidoreductase inhibitors
NAD(P)H2 dehydrogenase (quinone) inhibitor
NAD(P)H2 dehydrogenase (quinone) inhibitors
NAD(P)H: menadione oxidoreductase inhibitor
NAD(P)H: menadione oxidoreductase inhibitors
NAD(P)H:(quinone-acceptor)oxidoreductase inhibitor
NAD(P)H:(quinone-acceptor)oxidoreductase inhibitors
NAD(P)H:quinone oxidoreductase inhibitor
NAD(P)H:quinone oxidoreductase inhibitors
dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone) inhibitor
dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone) inhibitors
flavoprotein NAD(P)H-quinone reductase inhibitor
flavoprotein NAD(P)H-quinone reductase inhibitors
reduced NAD(P)H dehydrogenase inhibitors
reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase inhibitor
reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase inhibitors
viologen accepting pyridine nucleotide oxidoreductase inhibitor
viologen accepting pyridine nucleotide oxidoreductase inhibitors
substance with EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor role
A role played by a molecular entity used to study the microscopic environment.
An acid or base which exhibits a colour change on neutralization by the basic or acidic titrant at or near the equivalence point of a titration.
Anything used in a scientific experiment that gives a visual change to indicate the presence of a substance or quality, change in a body, etc.
A substance which is adsorbed or desorbed with concomitant colour change at or near the equivalence point of a titration.
substance with adsorption indicator role
A colour indicator that is colourless on one side of the transition interval.
substance with one-colour indicator role
A colour indicator that possesses a different colour on each side of the transition interval.
substance with two-colour indicator role
An EC 1.6.3.* (oxidoreductase acting on NADH or NADPH with oxygen as acceptor) inhibitor that interferes with the action of NAD(P)H oxidase (H2O2-forming), EC 1.6.3.1.
EC 1.6.3.1. (NAD(P)H oxidase (H2O2-forming)) inhibitor
EC 1.6.3.1. (NAD(P)H oxidase (H2O2-forming)) inhibitors
EC 1.6.3.1. [NAD(P)H oxidase (H2O2-forming)] inhibitors
NAD(P)H oxidase (H2O2-forming) (EC 1.6.3.1) inhibitor
NAD(P)H oxidase (H2O2-forming) (EC 1.6.3.1) inhibitors
NAD(P)H oxidase (H2O2-forming) inhibitor
NAD(P)H oxidase (H2O2-forming) inhibitors
NAD(P)H:oxygen oxidoreductase (H2O2-forming) inhibitor
NAD(P)H:oxygen oxidoreductase (H2O2-forming) inhibitors
NAD(P)H:oxygen oxidoreductase inhibitors
substance with EC 1.6.3.1. [NAD(P)H oxidase (H2O2-forming)] inhibitor role
A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
substance with platelet aggregation inhibitor role
Antagonist of platelet surface glycoprotein-IIb/IIIa which has a key role in hemostasis and thrombosis such as platelet adhesion and aggregation.
glycoprotein-IIb/IIIa receptor antagonist
glycoprotein-IIb/IIIa receptor antagonists
platelet glycoprotein-IIb/IIIa receptor antagonists
substance with platelet glycoprotein-IIb/IIIa receptor antagonist role
substance with adenosine phosphodiesterase inhibitor role
An EC 3.5.4.* (non-peptide cyclic amidine C-N hydrolase) inhibitor that interferes with the action of adenosine deaminase (EC 3.5.4.4).
EC 3.5.4.4 (adenosine deaminase) inhibitors
adenosine deaminase (EC 3.5.4.4) inhibitor
adenosine deaminase (EC 3.5.4.4) inhibitors
substance with EC 3.5.4.4 (adenosine deaminase) inhibitor role
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of phospholipase A2 (EC 3.1.1.4).
EC 3.1.1.4 (phospholipase A2) inhibitors
phosphatidylcholine 2-acylhydrolase inhibitor
phosphatidylcholine 2-acylhydrolase inhibitors
phospholipase A2 (EC 3.1.1.4) inhibitors
substance with EC 3.1.1.4 (phospholipase A2) inhibitor role
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of dihydropteroate synthase (EC 2.5.1.15), an enzyme that catalyzes the formation of dihydropteroate from p-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate.
(2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase inhibitor
(2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase inhibitors
2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase inhibitor
2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase inhibitors
7,8-dihydropteroate synthetase inhibitor
7,8-dihydropteroate synthetase inhibitors
7,8-dihydropteroic acid synthetase inhibitor
7,8-dihydropteroic acid synthetase inhibitors
EC 2.5.1.15 (dihydropteroate synthase) inhibitors
dihydropteroate diphosphorylase inhibitor
dihydropteroate diphosphorylase inhibitors
dihydropteroate pyrophosphorylase inhibitor
dihydropteroate pyrophosphorylase inhibitors
dihydropteroate synthase (EC 2.5.1.15) inhibitor
dihydropteroate synthase (EC 2.5.1.15) inhibitors
substance with EC 2.5.1.15 (dihydropteroate synthase) inhibitor role
An agent that produces a soft formed stool, and relaxes and loosens the bowels, typically used over a protracted period, to relieve constipation. Compare with cathartic, which is a substance that accelerates defecation. A substances can be both a laxative and a cathartic.
Compound that increase urine volume by increasing the amount of osmotically active solute in the urine. It also increases the osmolarity of plasma.
Substance that sweeten food, beverages, medications, etc.
Any agent that is used to decrease appetite.
An agent that inhibits cell membrane glycoproteins that are selectively permeable to potassium ions.
substance with potassium channel blocker role
substance with potassium channel modulator role
Agent that dilates the pupil. Used in eye diseases and to facilitate eye examination. It may be either a sympathomimetic or parasympatholytic. The latter cause cycloplegia or paralysis of accommodation at high doses and may precipitate glaucoma.
Drug used to cause constriction of the blood vessels.
substance with vasoconstrictor agent role
An agent, with unique chemical structure and biochemical requirements, which generates nitric oxide.
An EC 3.1.4.* (phosphoric diester hydrolase) inhibitor which interferes with the action of 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17).
3',5'-cyclic nucleoside monophosphate phosphodiesterase inhibitor
3',5'-cyclic nucleoside monophosphate phosphodiesterase inhibitors
3',5'-cyclic-nucleotide 5'-nucleotidohydrolase inhibitor
3',5'-cyclic-nucleotide 5'-nucleotidohydrolase inhibitors
3',5'-cyclic-nucleotide phosphodiesterase inhibitor
3',5'-cyclic-nucleotide phosphodiesterase inhibitors
3',5'-cyclonucleotide phosphodiesterase inhibitor
3',5'-cyclonucleotide phosphodiesterase inhibitors
3',5'-nucleotide phosphodiesterase inhibitor
3',5'-nucleotide phosphodiesterase inhibitors
3': 5'-monophosphate phosphodiesterase (cyclic CMP) inhibitor
3': 5'-monophosphate phosphodiesterase (cyclic CMP) inhibitors
3':5'-cyclic nucleotide 5'-nucleotidohydrolase inhibitor
3':5'-cyclic nucleotide 5'-nucleotidohydrolase inhibitors
EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitors
cyclic 3',5'-mononucleotide phosphodiesterase inhibitor
cyclic 3',5'-mononucleotide phosphodiesterase inhibitors
cyclic 3',5'-nucleotide phosphodiesterase inhibitor
cyclic 3',5'-nucleotide phosphodiesterase inhibitors
cyclic 3',5'-phosphodiesterase inhibitor
cyclic 3',5'-phosphodiesterase inhibitors
cyclic 3',5-nucleotide monophosphate phosphodiesterase inhibitor
cyclic 3',5-nucleotide monophosphate phosphodiesterase inhibitors
cyclic nucleotide phosphodiesterase inhibitor
cyclic nucleotide phosphodiesterase inhibitors
cytidine 3':5'-monophosphate phosphodiesterase (cyclic CMP) inhibitor
cytidine 3':5'-monophosphate phosphodiesterase (cyclic CMP) inhibitors
nucleoside 3',5'-cyclic phosphate diesterase inhibitor
nucleoside 3',5'-cyclic phosphate diesterase inhibitors
nucleoside-3',5-monophosphate phosphodiesterase inhibitor
nucleoside-3',5-monophosphate phosphodiesterase inhibitors
substance with EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor role
An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of alpha-amylase (EC 3.2.1.1).
1,4-alpha-D-glucan glucanohydrolase inhibitor
1,4-alpha-D-glucan glucanohydrolase inhibitors
4-alpha-D-glucan glucanohydrolase inhibitor
4-alpha-D-glucan glucanohydrolase inhibitors
substance with EC 3.2.1.1 (alpha-amylase) inhibitor role
A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2.
prostaglandin-endoperoxide synthase 2 inhibitor
prostaglandin-endoperoxide synthase 2 inhibitors
substance with cyclooxygenase 2 inhibitor role
A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 1.
prostaglandin-endoperoxide synthase 1 inhibitor
prostaglandin-endoperoxide synthase 1 inhibitors
substance with cyclooxygenase 1 inhibitor role
EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the activity of urease (EC 3.5.1.5), reducing hydrolysis.
substance with EC 3.5.1.5 (urease) inhibitor role
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of dimethylallyltranstransferase (EC 2.5.1.1).
(2E,6E)-farnesyl diphosphate synthetase inhibitor
(2E,6E)-farnesyl diphosphate synthetase inhibitors
DMAPP:IPP-dimethylallyltransferase inhibitor
DMAPP:IPP-dimethylallyltransferase inhibitors
EC 2.5.1.1 (dimethylallyltranstransferase) inhibitors
dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase inhibitor
dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase inhibitors
dimethylallyltranstransferase (EC 2.5.1.1) inhibitor
dimethylallyltranstransferase (EC 2.5.1.1) inhibitors
dimethylallyltranstransferase inhibitors
geranyl pyrophosphate synthase inhibitor
geranyl pyrophosphate synthase inhibitors
geranyl pyrophosphate synthetase inhibitor
geranyl pyrophosphate synthetase inhibitors
trans-farnesyl pyrophosphate synthetase inhibitor
trans-farnesyl pyrophosphate synthetase inhibitors
substance with EC 2.5.1.1 (dimethylallyltranstransferase) inhibitor role
An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis.
substance with bone density conservation agent role
substance with matrix metalloproteinase inhibitor role
A drug used to treat hyperthyroidism by reducing the excessive production of thyroid hormones.
An EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of dihydrofolate reductase (EC 1.5.1.3).
EC 1.5.1.3 (dihydrofolate reductase) inhibitors
NADPH-dihydrofolate reductase inhibitors
dihydrofolate reductase (EC 1.5.1.3) inhibitor
dihydrofolate reductase (EC 1.5.1.3) inhibitors
tetrahydrofolate dehydrogenase inhibitor
tetrahydrofolate dehydrogenase inhibitors
substance with EC 1.5.1.3 (dihydrofolate reductase) inhibitor role
A reagent with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between macromolecules, principally side chains of amino acids in proteins, allowing the locations of naturally reactive areas within the proteins to be identified.
substance with cross-linking reagent role
A drug used to treat trichomonas infections.
substance with antitrichomonal drug role
A substance used either in the prevention or facilitation of pregnancy.
substance with reproductive control drug role
A chemical substance that interrupts pregnancy after implantation.
An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of peptidoglycan glycosyltransferase (EC 2.4.1.129).
EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitors
[poly-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide)]-diphosphoundecaprenol:[N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide]-diphosphoundecaprenol disaccharidetransferase inhibitor
[poly-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide)]-diphosphoundecaprenol:[N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide]-diphosphoundecaprenol disaccharidetransferase inhibitors
bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase inhibitor
bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase inhibitors
penicillin binding protein 1B inhibitors
peptidoglycan glycosyltransferase (EC 2.4.1.129) inhibitor
peptidoglycan glycosyltransferase (EC 2.4.1.129) inhibitors
peptidoglycan glycosyltransferase inhibitor
peptidoglycan glycosyltransferase inhibitors
peptidoglycan transglycosylase inhibitor
peptidoglycan transglycosylase inhibitors
undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase inhibitor
undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase inhibitors
substance with EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor role
A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance.
A substance that possess antiestrogenic actions but can also produce estrogenic effects as well. It acts as complete or partial agonist or as antagonist. It can be either steroidal or nonsteroidal in structure.
substance with estrogen receptor modulator role
Any retinoic acid receptor (RAR) agonist with specificity for RARalpha and RARbeta.
substance with retinoic acid receptor alpha/beta agonist role
A compound that interacts with progesterone receptors in target tissues to bring about effects similar to those of progesterone.
A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.
DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitor
DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitors
DNA topoisomerase (ATP-hydrolysing) inhibitor
DNA topoisomerase (ATP-hydrolysing) inhibitors
EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitor
EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitors
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitors
substance with EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor role
A drug which acts to reduce estrogenic activity in the body, either by reducing the amount of estrogen or by reducing the activity of whatever estrogen is present.
An agent which regulates the physiologic mechanisms that control the appetite and food intake.
An EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of of 3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)), EC 1.3.1.22, the enzyme which converts testosterone (GOCHE:17347) into the more potent androgen 5alpha-dihydrotestosterone.
3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)) (EC 1.3.1.22) inhibitor
3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)) (EC 1.3.1.22) inhibitors
3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)) inhibitor
3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)) inhibitors
3-oxo-5alpha-steroid 4-dehydrogenase inhibitor
3-oxo-5alpha-steroid 4-dehydrogenase inhibitors
3-oxo-5alpha-steroid:NADP+ Delta(4)-oxidoreductase inhibitor
3-oxo-5alpha-steroid:NADP+ Delta(4)-oxidoreductase inhibitors
3-oxosteroid Delta4-dehydrogenase inhibitor
4-ene-3-oxosteroid 5alpha-reductase inhibitor
Delta(4)-3-ketosteroid 5alpha-oxidoreductase inhibitor
Delta(4)-3-ketosteroid 5alpha-oxidoreductase inhibitors
EC 1.3.1.22 (3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))) inhibitor
EC 1.3.1.22 (3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))) inhibitors
EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitors
cholest-4-en-3-one 5alpha-reductase inhibitor
cholestenone 5alpha-reductase inhibitors
reduced nicotinamide adenine dinucleotide phosphate:Delta(4)-3-ketosteroid 5alpha-oxidoreductase inhibitor
reduced nicotinamide adenine dinucleotide phosphate:Delta(4)-3-ketosteroid 5alpha-oxidoreductase inhibitors
testosterone 5alpha-reductase inhibitors
testosterone Delta(4)-5alpha-reductase inhibitor
testosterone Delta(4)-5alpha-reductase inhibitors
testosterone Delta(4)-hydrogenase inhibitor
testosterone Delta(4)-hydrogenase inhibitors
substance with EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor role
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor which interferes with the action of 3beta-hydroxysteroid dehydrogenase (EC 1.1.1.210), a group of steroidogenic enzymes.
3beta (or 20alpha)-hydroxysteroid dehydrogenase inhibitor
3beta (or 20alpha)-hydroxysteroid dehydrogenase inhibitors
3beta(or 20alpha)-hydroxysteroid dehydrogenase (EC 1.1.1.210) inhibitor
3beta(or 20alpha)-hydroxysteroid dehydrogenase (EC 1.1.1.210) inhibitors
3beta(or 20alpha)-hydroxysteroid dehydrogenase inhibitor
3beta(or 20alpha)-hydroxysteroid dehydrogenase inhibitors
3beta(or 20alpha)-hydroxysteroid:NADP(+) oxidoreductase inhibitor
3beta(or 20alpha)-hydroxysteroid:NADP(+) oxidoreductase inhibitors
3beta,20alpha-hydroxysteroid oxidoreductase inhibitor
3beta,20alpha-hydroxysteroid oxidoreductase inhibitors
3beta-hydroxysteroid dehydrogenase inhibitor
EC 1.1.1.210 (3beta(or 20alpha)-hydroxysteroid dehydrogenase) inhibitor
EC 1.1.1.210 (3beta(or 20alpha)-hydroxysteroid dehydrogenase) inhibitors
EC 1.1.1.210 [3beta(or 20alpha)-hydroxysteroid dehydrogenase] inhibitors
dehydrogenase, 3beta,20alpha-hydroxy steroid inhibitor
dehydrogenase, 3beta,20alpha-hydroxy steroid inhibitors
substance with EC 1.1.1.210 [3beta(or 20alpha)-hydroxysteroid dehydrogenase] inhibitor role
An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor which interferes with the action of aromatase (EC 1.14.14.14) and so reduces production of estrogenic steroid hormones.
substance with EC 1.14.14.14 (aromatase) inhibitor role
substance with estrogen receptor antagonist role
A drug used to treat hyperparathyroidism by reducing the excessive production of parathyroid hormones.
substance with antiparathyroid drug role
A compound which inhibits or antagonises the biosynthesis or actions of estrogens.
A compound which inhibits or antagonizes the biosynthesis or actions of mineralocorticoids, a class of steroid hormones characterised by their similarity to aldosterone and their influence on salt and water balance.
substance with antimineralocorticoid role
substance with aldosterone antagonist role
Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity.
substance with immunological adjuvant role
A cardiovascular drug that prevents atherogenesis, the accumulation of lipid-containing plaques on the innermost layers of the arteries. Compare with antiatherosclerotic agent.
substance with antiatherogenic agent role
A drug used to treat allergic reactions.
An agent which overcomes insulin resistance by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma).
peroxisome proliferator-activated receptor gamma agonist
peroxisome proliferator-activated receptor gamma agonists
proliferator activated receptor gamma agonist
proliferator activated receptor gamma agonists
substance with insulin-sensitizing drug role
A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells.
A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy.
A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect.
A role is particular behaviour which a material entity may exhibit.
A deaminating agent is a role played by a chemical agent which exhibits the capability of causing the loss of an amine functional group on another molecular entity (e.g. DNA or protein).
A role played by a chemical compound exhibiting itself through the ability to induce damage to the liver in animals.
A role played by any chemical compound (natural or synthetic) exhibiting itself through the ability to induce damage to the kidneys.
A poison that interferes with the functions of the nervous system.
A role played by a chemical compound exhibiting itself through the ability to induce damage to the heart and cardiomyocytes.
Any compound used for the purpose of preserving biological tissues from decay in such a way as to allow for the preparation of thin, stained sections for subsequent histological study.
An inhibitor of phosphatidylinositol 3-kinase, EC 2.7.1.137, a family of related enzymes capable of phosphorylating the 3 position hydroxy group of the inositol ring of a phosphatidylinositol.
1-phosphatidylinositol 3-kinase inhibitor
1-phosphatidylinositol 3-kinase inhibitors
ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase inhibitor
ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase inhibitors
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitors
phosphatidylinositol 3-kinase (EC 2.7.1.137) inhibitor
phosphatidylinositol 3-kinase (EC 2.7.1.137) inhibitors
phosphatidylinositol 3-kinase inhibitors
phosphatidylinositol-3-OH kinase inhibitor
phosphatidylinositol-3-OH kinase inhibitors
type I phosphatidylinositol kinase inhibitor
type I phosphatidylinositol kinase inhibitors
type III phosphoinositide 3-kinase inhibitor
type III phosphoinositide 3-kinase inhibitors
substance with EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor role
An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of lipid kinases.
substance with lipid kinase inhibitor role
A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors.
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of non-specific serine/threonine protein kinase (EC 2.7.11.1), a kinase enzyme involved in phosphorylation of hydroxy group of serine or threonine.
ATP-protein transphosphorylase inhibitor
ATP-protein transphosphorylase inhibitors
ATP:protein phosphotransferase (non-specific) inhibitor
ATP:protein phosphotransferase (non-specific) inhibitors
BR serine/threonine-protein kinase 2 inhibitor
BR serine/threonine-protein kinase 2 inhibitors
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitors
cAMP-dependent protein kinase A inhibitor
cAMP-dependent protein kinase A inhibitors
cAMP-dependent protein kinase inhibitors
cGMP-dependent protein kinase inhibitors
calcium/phospholipid-dependent protein kinase inhibitor
calcium/phospholipid-dependent protein kinase inhibitors
casein kinase (phosphorylating) inhibitor
casein kinase (phosphorylating) inhibitors
cyclic AMP-dependent protein kinase A inhibitor
cyclic AMP-dependent protein kinase A inhibitors
cyclic AMP-dependent protein kinase inhibitor
cyclic AMP-dependent protein kinase inhibitors
cyclic monophosphate-dependent protein kinase inhibitor
cyclic monophosphate-dependent protein kinase inhibitors
cyclic nucleotide-dependent protein kinase inhibitor
cyclic nucleotide-dependent protein kinase inhibitors
non-specific serine/threonine protein kinase (EC 2.7.11.1) inhibitor
non-specific serine/threonine protein kinase (EC 2.7.11.1) inhibitors
non-specific serine/threonine protein kinase inhibitor
non-specific serine/threonine protein kinase inhibitors
phosphorylase b kinase kinase inhibitors
protein kinase (phosphorylating) inhibitor
protein kinase (phosphorylating) inhibitors
protein serine-threonine kinase inhibitor
protein serine-threonine kinase inhibitors
protein-serine/threonine kinase inhibitors
ribosomal protein S6 kinase II inhibitor
ribosomal protein S6 kinase II inhibitors
serine(threonine) protein kinase inhibitor
serine(threonine) protein kinase inhibitors
serine-specific protein kinase inhibitor
serine-specific protein kinase inhibitors
serine/threonine protein kinase inhibitor
serine/threonine protein kinase inhibitors
threonine-specific protein kinase inhibitor
threonine-specific protein kinase inhibitors
substance with EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor role
An agent that modulates the physiologic angiogenesis process. This is accomplished by endogenous angiogenic proteins and a variety of other chemicals and pharmaceutical agents.
substance with angiogenesis modulating agent role
A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.
substance with serotonin uptake inhibitor role
A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
substance with dopamine uptake inhibitor role
A chemical substance which binds to specific hormone receptors activating the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.
A drug that modulates the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.
substance with hormone receptor modulator role
A drug that binds to and activates dopamine receptors.
An agent causing contraction of the pupil of the eye. Because the size of the pupil is under the antagonistic control of the sympathetic and parasympathetic systems, drugs affecting either system can cause miosis. Drugs that mimic or potentiate the parasympathetic input to the circular constrictor muscle and drugs that inhibit sympathetic input to the radial dilator muscle tend to contract the pupils.
A compound that inhibits the growth of marine organisms.
A role played by the molecular entity or part thereof within a chemical context.
A group that is introduced into a molecule by chemical modification of a functional group in order to obtain chemoselectivity in a subsequent chemical reaction.
A role played by a phosphonium ylide in a Wittig reaction.
An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
A fluorescent dye used to stain biological specimens.
A role played by an organomagnesium halide in a Grignard reaction.
A role played by a compound in a fluid state in swelling a gel, network, or solid.
A role played by a compound that facilitates the rapid drying of gels without their cracking.
substance with drying control chemical additive role
A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis.
A drug used for its actions on skeletal muscle.
A drug that binds to and activates gamma-aminobutyric acid receptors.
gamma-aminobutyric acid receptor agonist
gamma-aminobutyric acid receptor agonists
A substance, such as agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function, used for its pharmacological actions on GABAergic systems.
A hormone antagonist that blocks endothelin receptors.
substance with endothelin receptor antagonist role
A endothelin receptor antagonist is a drug which selectively blocks endothelin A receptors.
substance with endothelin A receptor antagonist role
A compound which binds and activates the prostacyclin receptor IP1, but has only partial efficacy at the receptor relative to a full agonist.
substance with partial prostacyclin agonist role
A biological role played by the molecular entity or part thereof within a biochemical context.
A role played by the molecular entity or part thereof which causes the development of a pathological process.
substance with aetiopathogenetic role role
A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties.
substance with pharmacological role role
Any molecule or ion capable of binding to a central metal atom to form coordination complexes.
A chemical role played by the molecular entity or part thereof in a photochemical process.
A role played by a molecular entity or part thereof in a photobiochemical process.
substance with photobiochemical role role
Any substance introduced into a living organism with therapeutic or diagnostic purpose.
An organic dye characterized by an aromatic four-membered ring system derived from squaric acid.
A chemical substance that encourages a cell to commence cell division, triggering mitosis.
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of sterol methyltransferase.
substance with sterol methyltransferase inhibitor role
An EC 3.2.* (glycosylase) inhibitor that interferes with the action of any glycosidase (i.e. enzymes hydrolysing O- and S-glycosyl compounds, EC 3.2.1.*).
substance with EC 3.2.1.* (glycosidase) inhibitor role
An antiviral drug targeted at influenza viruses. Its mode of action consists of blocking the function of the viral neuraminidase protein (EC 3.2.1.18), thus preventing the virus from budding from the host cell.
EC 3.2.1.18 (exo-alpha-sialidase) inhibitors
N-acylneuraminate glycohydrolase inhibitor
N-acylneuraminate glycohydrolase inhibitors
exo-alpha-sialidase (EC 3.2.1.18) inhibitor
exo-alpha-sialidase (EC 3.2.1.18) inhibitors
substance with EC 3.2.1.18 (exo-alpha-sialidase) inhibitor role
An inhibitor of ribonuclease H (EC 3.1.26.13), an enzyme required for specific hydrolysis of the RNA strand of an RNA/DNA hybrid.
EC 3.1.26.13 (retroviral ribonuclease H) inhibitors
retroviral reverse transcriptase RNaseH inhibitor
retroviral reverse transcriptase RNaseH inhibitors
retroviral ribonuclease H (EC 3.1.26.13) inhibitor
retroviral ribonuclease H (EC 3.1.26.13) inhibitors
substance with EC 3.1.26.13 (retroviral ribonuclease H) inhibitor role
A drug that blocks the action of proteasomes, cellular complexes that break down proteins.
substance with proteasome inhibitor role
A group that serves to protect a phosphate group in the context of a synthesis.
substance with phosphate protecting group role
A group that serves to protect a carboxylic acid function in the context of a synthesis.
substance with carboxylic acid protecting group role
The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds.
substance with adenosine A2A receptor antagonist role
A compound that exhibits agonist activity at the P2Y2 receptor.
substance with P2Y2 receptor agonist role
A substance used to cause adherence of tissue to tissue or tissue to non-tissue surfaces, as for prostheses.
A drug that binds to and activates gamma-hydroxybutyric acid receptors.
substance with GHB receptor agonist role
The role played by a molecular entity, such as an atom or free radical, which is involved in chain-propagating reactions.
A topoisomerase inhibitor that inhibits DNA topoisomerase IV, which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.
substance with topoisomerase IV inhibitor role
An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of diamine oxidase (EC 1.4.3.22).
EC 1.4.3.22 (diamine oxidase) inhibitors
diamine oxidase (EC 1.4.3.22) inhibitors
histamine:oxygen oxidoreductase (deaminating) inhibitor
histamine:oxygen oxidoreductase (deaminating) inhibitors
substance with EC 1.4.3.22 (diamine oxidase) inhibitor role
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of IMP dehydrogenase (EC 1.1.1.205), so blocking de novo biosynthesis of purine nucleotides.
EC 1.1.1.205 (IMP dehydrogenase) inhibitors
IMP dehydrogenase (EC 1.1.1.205) inhibitor
IMP dehydrogenase (EC 1.1.1.205) inhibitors
inosine 5'-monophosphate dehydrogenase inhibitors
inosine monophosphate dehydrogenase inhibitor
inosine monophosphate dehydrogenase inhibitors
inosine monophosphate oxidoreductase inhibitor
inosine monophosphate oxidoreductase inhibitors
substance with EC 1.1.1.205 (IMP dehydrogenase) inhibitor role
An entity which inhibits the activity of HIV-1 reverse transcriptase.
substance with HIV-1 reverse transcriptase inhibitor role
A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder.
A compound that exhibits agonist activity at the mu-opioid receptor.
substance with mu-opioid receptor agonist role
Any drug found useful in the symptomatic treatment of diarrhoea.
A drug used for its effects on the gastrointestinal system, e.g. controlling gastric acidity, regulating gastrointestinal motility and water flow, and improving digestion.
substance with gastrointestinal drug role
A class of anticoagulants which act by inhibiting the action of vitamin K.
substance with vitamin K antagonist role
An antagonist at the neurokinin-1 receptor.
substance with neurokinin-1 receptor antagonist role
An antagonist at the substance P receptor.
substance with substance P receptor antagonist role
A drug or agent applied to the skin to control seborrhea or seborrheic dermatitis.
Any inhibitor of an acid--D-amino-acid ligase (EC 6.3.2.*).
EC 6.3.2.* (acid--D-amino-acid ligase (peptide synthase)) inhibitor
EC 6.3.2.* (acid--D-amino-acid ligase (peptide synthase)) inhibitors
EC 6.3.2.* (acid--D-amino-acid ligase) inhibitors
EC 6.3.2.* (acid--amino-acid ligase) inhibitor
EC 6.3.2.* (acid--amino-acid ligase) inhibitors
EC 6.3.2.* [acid--D-amino-acid ligase (peptide synthase)] inhibitor
EC 6.3.2.* [acid--D-amino-acid ligase (peptide synthase)] inhibitors
substance with EC 6.3.2.* (acid--D-amino-acid ligase) inhibitor role
Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of a metalloendopeptidase (EC 3.4.24.*).
EC 3.4.24.* (metalloendopeptidase) inhibitors
inhibitor of metalloendopeptidases (EC 3.4.24.*)
inhibitors of metalloendopeptidases (EC 3.4.24.*)
metalloendopeptidase (EC 3.4.24.*) inhibitor
metalloendopeptidase (EC 3.4.24.*) inhibitors
substance with EC 3.4.24.* (metalloendopeptidase) inhibitor role
Any substance that stimulates an immune response in the body, such as through antibody production or by presentation to a T-cell receptor after binding to a major histocompability complex (MHC).
A substance used as an indicator of a biological state.
Any substance capable of eliciting an immune response only when attached to a large carrier such as a protein. Examples include dinitrophenols; oligosaccharides; peptides; and heavy metals.
A chemical substance which inhibits the function of gonadotrophin-releasing hormone (GnRH).
gonadotrophin-releasing hormone antagonist
gonadotrophin-releasing hormone antagonists
Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that inhibits the activity of a serine endopeptidase (EC 3.4.21.*).
EC 3.4.21.* (serine endopeptidase) inhibitors
inhibitor of serine endopeptidase (EC 3.4.21.*)
inhibitor of serine endopeptidase (EC 3.4.21.*)s
substance with EC 3.4.21.* (serine endopeptidase) inhibitor role
A compound that exhibits agonist activity at the kappa-opioid receptor.
substance with kappa-opioid receptor agonist role
Any compound that exhibits antagonist activity at the delta-opioid receptor.
substance with delta-opioid receptor antagonist role
An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of squalene monooxygenase (EC 1.14.13.132).
EC 1.14.13.132 (squalene monooxygenase) inhibitors
squalene monooxygenase (EC 1.14.13.132) inhibitor
squalene monooxygenase (EC 1.14.13.132) inhibitors
substance with EC 1.14.13.132 (squalene monooxygenase) inhibitor role
An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of aromatic-L-amino-acid decarboxylase (EC 4.1.1.28).
5-hydroxytryptophan decarboxylase inhibitor
5-hydroxytryptophan decarboxylase inhibitors
EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitors
aromatic amino acid decarboxylase inhibitor
aromatic amino acid decarboxylase inhibitors
aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) inhibitor
aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) inhibitors
aromatic-L-amino-acid decarboxylase inhibitor
aromatic-L-amino-acid decarboxylase inhibitors
hydroxytryptophan decarboxylase inhibitor
hydroxytryptophan decarboxylase inhibitors
substance with EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor role
Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that inhibits the action of a dipeptidase (EC 3.4.13.*).
substance with EC 3.4.13.* (dipeptidase) inhibitor role
Any substance that inhibits the synthesis of DNA.
substance with DNA synthesis inhibitor role
Any antigen that is a phosphorylated microbial metabolite which activates an immune response in humans.
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of serine palmitoyltransferase (EC 2.3.1.50).
EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitors
acyl-CoA:serine C-2 acyltransferase (decarboxylating) inhibitor
acyl-CoA:serine C-2 acyltransferase (decarboxylating) inhibitors
palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) inhibitor
palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) inhibitors
serine C-palmitoyltransferase (EC 2.3.1.50) inhibitor
serine C-palmitoyltransferase (EC 2.3.1.50) inhibitors
serine C-palmitoyltransferase inhibitors
substance with EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor role
A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of chitin synthase (EC 2.4.1.16).
EC 2.4.1.16 (chitin synthase) inhibitors
UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase inhibitor
UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase inhibitors
chitin synthase (EC 2.4.1.16) inhibitors
chitin-UDP N-acetylglucosaminyltransferase inhibitor
chitin-UDP N-acetylglucosaminyltransferase inhibitors
chitin-UDP acetyl-glucosaminyl transferase inhibitor
chitin-UDP acetyl-glucosaminyl transferase inhibitors
chitin-uridine diphosphate acetylglucosaminyltransferase inhibitor
chitin-uridine diphosphate acetylglucosaminyltransferase inhibitors
trans-N-acetylglucosaminosylase inhibitor
trans-N-acetylglucosaminosylase inhibitors
substance with EC 2.4.1.16 (chitin synthase) inhibitor role
Any drug which blocks vasopressin receptors.
arginine vasopressin receptor antagonist
arginine vasopressin receptor antagonists
substance with vasopressin receptor antagonist role
A drug, usually applied topically, that relieves pruritus (itching).
Any drug which binds to vasopressin receptors and triggers a response.
substance with vasopressin receptor agonist role
A reagent that forms a bond to its reaction partner (the nucleophile) by accepting both bonding electrons from that reaction partner.
substance with electrophilic reagent role
A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons.
substance with nucleophilic reagent role
A reagent used to improve selectivity in chromatographic analyses or separations, e.g. by formation of a derivative or by modification of the mobile phase.
substance with chromatographic reagent role
A surfactant molecule with hydrophilic groups at both ends of a hydrophobic hydrocarbon chain
A drug used for the treatment of hyperplasia (increaced cell production within an organ or tissue).
substance with antihyperplasia drug role
Any drug used to depigment skin, normally by decreasing the excretion of melanin from melanocytes.
A drug which interferes with the binding, fusion and entry of an HIV virion to a human cell. By blocking this step in HIV's replication cycle, such agents slow the progression from HIV infection to AIDS.
substance with HIV fusion inhibitor role
A DNA polymerase inhibitor that interferes with the activity of reverse transcriptase, EC 2.7.7.49, a viral DNA polymerase enzyme that retroviruses need in order to reproduce.
DNA nucleotidyltransferase (RNA-directed) inhibitor
DNA nucleotidyltransferase (RNA-directed) inhibitors
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitors
RNA-dependent deoxyribonucleate nucleotidyltransferase inhibitor
RNA-dependent deoxyribonucleate nucleotidyltransferase inhibitors
RNA-directed DNA polymerase (EC 2.7.7.49) inhibitor
RNA-directed DNA polymerase (EC 2.7.7.49) inhibitors
RNA-instructed DNA polymerase inhibitors
deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) inhibitor
deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) inhibitors
substance with EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor role
A surfactant molecule possessing both hydrophilic and lipophilic properties.
Any EC 1.14.18.* (oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen) inhibitor that interferes with the action of tyrosinase (monophenol monooxygenase), EC 1.14.18.1, an enzyme that catalyses the oxidation of phenols (such as tyrosine) and is widespread in plants and animals.
L-tyrosine,L-dopa:oxygen oxidoreductase inhibitor
L-tyrosine,L-dopa:oxygen oxidoreductase inhibitors
NN-acetyl-6-hydroxytryptophan oxidase inhibitor
NN-acetyl-6-hydroxytryptophan oxidase inhibitors
monophenol dihydroxyphenylalanine:oxygen oxidoreductase inhibitor
monophenol dihydroxyphenylalanine:oxygen oxidoreductase inhibitors
monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase inhibitor
monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase inhibitors
substance with EC 1.14.18.1 (tyrosinase) inhibitor role
An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of Ca(2+)-transporting ATPase (EC 3.6.3.8).
ATP phosphohydrolase (Ca(2+)-transporting) inhibitor
ATP phosphohydrolase (Ca(2+)-transporting) inhibitors
Ca(2+)-transporting ATPase (EC 3.6.3.8) inhibitor
Ca(2+)-transporting ATPase (EC 3.6.3.8) inhibitors
EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitors
sarco(endo)plasmic reticulum Ca(2+)-ATPase inhibitor
sarco(endo)plasmic reticulum Ca(2+)-ATPase inhibitors
sarcoplasmic reticulum ATPase inhibitors
substance with EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor role
Any macromolecule whose structure mimics that of an epitope. When applied to immunisation, a mimotope induces the desired antibody specificities exclusively based on the principle of molecular mimicry.
A hydrolase inhibitor that interferes with the action of any hydrolase acting on peptide bonds (peptidase), EC 3.4.*.*).
EC 3.4.* (hydrolase acting on peptide bond) inhibitor
EC 3.4.* (hydrolase acting on peptide bonds) inhibitors
EC 3.4.* (hydrolases acting on peptide bond) inhibitors
inhibitor of hydrolases acting on peptide bond (EC 3.4.*)
inhibitors of hydrolases acting on peptide bond (EC 3.4.*)
substance with EC 3.4.* (hydrolases acting on peptide bond) inhibitor role
Any EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the activity of a glutaminase (EC 3.5.1.2) and thus the generation of glutamate from glutamine.
substance with EC 3.5.1.2 (glutaminase) inhibitor role
Any hormone produced by the thyroid gland
Any member of the class of herbicides whose members contain a phenoxy or substituted phenoxy group.
Any agent that acts on an opioid receptor or affects the life cycle of an opioid transmitter.
Any agent that acts on a mu-opioid receptor.
Any agent that acts on a delta-opioid receptor.
Any agent that acts on a kappa-opioid receptor.
An agent that binds to but does not activate an opioid receptor thereby blocking the actions of endogenous or exogenous opioid receptor agonists.
substance with opioid receptor antagonist role
An agent that selectively binds to and activates an opioid receptor.
substance with opioid receptor agonist role
Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs.
N-methyl-D-aspartate receptor antagonist
N-methyl-D-aspartate receptor antagonists
substance with NMDA receptor antagonist role
A chiral compound used to induce stereoselectivity into a reaction.
An agent which blocks glucagon receptors.
substance with glucagon receptor antagonist role
An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of tryptophan synthase (EC 4.2.1.20).
EC 4.2.1.20 (tryptophan synthase) inhibitors
L-serine hydro-lyase (adding indoleglycerol-phosphate) inhibitor
L-serine hydro-lyase (adding indoleglycerol-phosphate) inhibitors
indoleglycerol phosphate aldolase inhibitor
indoleglycerol phosphate aldolase inhibitors
tryptophan synthase (EC 4.2.1.20) inhibitor
tryptophan synthase (EC 4.2.1.20) inhibitors
substance with EC 4.2.1.20 (tryptophan synthase) inhibitor role
An enzyme inhibitor, generally irreversible, that is similar in structure to a particular substrate for a specific enzyme.
Any substance which inhibits the action of receptors for excitatory amino acids.
excitatory amino acid receptor antagonist
excitatory amino acid receptor antagonists
substance with excitatory amino acid antagonist role
Any substance that possesses little anaesthetic effect by itself, but which enhances or potentiates the anaesthetic action of other drugs when given at the same time.
substance with anaesthesia adjuvant role
Any pharmacological or immunological agent that modifies the effect of other agents such as drugs or vaccines while having few if any direct effects when given by itself.
An antigen capable, on its own, of inducing an immune response.
Any substance that interacts with tubulin to inhibit or promote polymerisation of microtubules.
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that inhibits the action of riboflavin synthase (EC 2.5.1.9).
6,7-dimethyl-8-(1-D-ribityl)lumazine:6,7-dimethyl-8-(1-D-ribityl)lumazine 2,3-butanediyltransferase inhibitor
6,7-dimethyl-8-(1-D-ribityl)lumazine:6,7-dimethyl-8-(1-D-ribityl)lumazine 2,3-butanediyltransferase inhibitors
EC 2.5.1.9 (riboflavin synthase) inhibitors
riboflavin synthase (EC 2.5.1.9) inhibitor
riboflavin synthase (EC 2.5.1.9) inhibitors
substance with EC 2.5.1.9 (riboflavin synthase) inhibitor role
A toxin that is produced by a biological organism such as a microbe, animal or plant which interferes with the function of the kidney in animals.
A hormone antagonist that blocks angiotensin receptors.
substance with angiotensin receptor antagonist role
A drug used in the treatment of bile or liver disorders.
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98).
EC 3.5.1.98 (histone deacetylase) inhibitors
histone deacetylase (EC 3.5.1.98) inhibitor
histone deacetylase (EC 3.5.1.98) inhibitors
substance with EC 3.5.1.98 (histone deacetylase) inhibitor role
An enzyme inhibitor that inhibits the action of inositol phosphorylceramide synthase.
substance with inositol phosphorylceramide synthase inhibitor role
An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of nitric oxide synthase (EC 1.14.13.39).
EC 1.14.13.39 (nitric oxide synthase) inhibitors
endothelium-derived relaxation factor-forming enzyme inhibitor
endothelium-derived relaxation factor-forming enzyme inhibitors
endothelium-derived relaxing factor synthase inhibitor
endothelium-derived relaxing factor synthase inhibitors
nitric oxide synthase (EC 1.14.13.39) inhibitor
nitric oxide synthase (EC 1.14.13.39) inhibitors
substance with EC 1.14.13.39 (nitric oxide synthase) inhibitor role
Any substance that interacts with tubulin to promote polymerisation of microtubules.
substance with microtubule-stabilising agent role
Any substance that interacts with tubulin to inhibit polymerisation of microtubules.
substance with microtubule-destabilising agent role
An agonist that selectively binds to and activates a metabotropic glutamate receptor.
metabotropic glutamate receptor agonists
substance with metabotropic glutamate receptor agonist role
Any donor that can transfer acyl groups between molecular entities.
An EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action of any glutamate synthase.
EC 1.4.7.1 [glutamate synthase (ferredoxin)] inhibitors
L-glutamate:ferredoxin oxidoreductase (transaminating) inhibitor
L-glutamate:ferredoxin oxidoreductase (transaminating) inhibitors
ferredoxin-dependent glutamate synthase inhibitor
ferredoxin-dependent glutamate synthase inhibitors
ferredoxin-glutamate synthase inhibitors
glutamate synthase (ferredoxin) (EC 1.4.7.1) inhibitor
glutamate synthase (ferredoxin) (EC 1.4.7.1) inhibitors
glutamate synthase (ferredoxin) inhibitor
glutamate synthase (ferredoxin) inhibitors
glutamate synthase (ferredoxin-dependent) inhibitor
glutamate synthase (ferredoxin-dependent) inhibitors
substance with EC 1.4.7.1 [glutamate synthase (ferredoxin)] inhibitor role
A class of secondary metabolites developed by many plants to influence the behaviour, growth or survival of herbivores, and thus acting as a defence against herbivory.
An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that interferes with the action of receptor protein-tyrosine kinase (EC 2.7.10.1).
ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type) inhibitor
ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type) inhibitors
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitors
ephrin-B3 receptor tyrosine kinase inhibitor
insulin receptor protein-tyrosine kinase inhibitor
neurite outgrowth regulating kinase inhibitor
novel oncogene with kinase-domain inhibitor
receptor protein tyrosine kinase inhibitor
receptor protein-tyrosine kinase (EC 2.7.10.1) inhibitor
receptor protein-tyrosine kinase (EC 2.7.10.1) inhibitors
receptor protein-tyrosine kinase inhibitor
receptor protein-tyrosine kinase inhibitors
substance with EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor role
A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell.
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of sphingosine N-acyltransferase (EC 2.3.1.24).
EC 2.3.1.24 (sphingosine N-acyltransferase) inhibitors
acyl-CoA:sphingosine N-acyltransferase inhibitor
acyl-CoA:sphingosine N-acyltransferase inhibitors
sphingosine N-acyltransferase (EC 2.3.1.24) inhibitor
sphingosine N-acyltransferase (EC 2.3.1.24) inhibitors
sphingosine N-acyltransferase inhibitors
substance with EC 2.3.1.24 (sphingosine N-acyltransferase) inhibitor role
An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the function of aconitase (EC 4.2.1.3).
EC 4.2.1.3 (aconitate hydratase) inhibitors
aconitate hydratase (EC 4.2.1.3) inhibitor
aconitate hydratase (EC 4.2.1.3) inhibitors
citrate(isocitrate) hydro-lyase (cis-aconitate-forming) inhibitor
citrate(isocitrate) hydro-lyase (cis-aconitate-forming) inhibitors
citrate(isocitrate) hydro-lyase inhibitor
citrate(isocitrate) hydro-lyase inhibitors
substance with EC 4.2.1.3 (aconitate hydratase) inhibitor role
An EC 3.11.1.* (hydrolases acting on C-P bonds of phosphono-acetaldehyde, -acetate, or -pyruvate) inhibitor that interferes with the action of phosphonopyruvate hydrolase (EC 3.11.1.3).
EC 3.11.1.3 (phosphonopyruvate hydrolase) inhibitors
phosphonopyruvate hydrolase (EC 3.11.1.3) inhibitor
phosphonopyruvate hydrolase (EC 3.11.1.3) inhibitors
substance with EC 3.11.1.3 (phosphonopyruvate hydrolase) inhibitor role
An antagonist that blocks glycine receptors.
substance with glycine receptor antagonist role
Any additive that enhances the efficiency of fuel.
Any compound that is able to prevent damage to the liver.
substance with hepatoprotective agent role
An EC 4.3.* (C-N lyase) inhibitor that interferes with the action of phenylalanine ammonia-lyase (EC 4.3.1.24).
EC 4.3.1.24 (phenylalanine ammonia-lyase) inhibitors
L-phenylalanine ammonia-lyase (trans-cinnamate-forming) inhibitor
L-phenylalanine ammonia-lyase (trans-cinnamate-forming) inhibitors
L-phenylalanine ammonia-lyase inhibitors
phenylalanine ammonia-lyase (EC 4.3.1.24) inhibitor
phenylalanine ammonia-lyase (EC 4.3.1.24) inhibitors
substance with EC 4.3.1.24 (phenylalanine ammonia-lyase) inhibitor role
An EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor which interferes with the action of aldehyde oxidase (EC 1.2.3.1).
EC 1.2.3.1 (aldehyde oxidase) inhibitors
aldehyde oxidase (EC 1.2.3.1) inhibitors
aldehyde:oxygen oxidoreductase inhibitor
aldehyde:oxygen oxidoreductase inhibitors
substance with EC 1.2.3.1 (aldehyde oxidase) inhibitor role
An agonist that selectively binds to and activates an odorant receptor.
substance with odorant receptor agonist role
Any compound that inhibits the action of tankyrase.
An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of a NAD(+) ADP-ribosyltransferase (EC 2.4.2.30).
ADP-ribosyltransferase (polymerising) inhibitor
ADP-ribosyltransferase (polymerising) inhibitors
ADP-ribosyltransferase (polymerizing) inhibitor
ADP-ribosyltransferase (polymerizing) inhibitors
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitors
NAD(+) ADP-ribosyltransferase (EC 2.4.2.30) inhibitor
NAD(+) ADP-ribosyltransferase (EC 2.4.2.30) inhibitors
NAD(+) ADP-ribosyltransferase inhibitors
NAD(+):poly(ADP-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitor
NAD(+):poly(ADP-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitors
NAD(+):poly(adenosine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitor
NAD(+):poly(adenosine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase inhibitors
poly(adenosine diphosphate ribose) polymerase inhibitor
poly(adenosine diphosphate ribose) polymerase inhibitors
substance with EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor role
An EC 2.4.99.* (glycosyltransferases transferring other glycosyl groups) inhibitor that interferes with the action of a sialyltransferase.
substance with sialyltransferase inhibitor role
The chemical role played by a substance that stabilizes an emulsion by increasing its kinetic stability.
A food additive used to form or maintain a uniform emulsion of two (or more) phases in a food.
Any compound that induces or regulates osteogenesis.
substance with osteogenesis regulator role
A catalyst that facilitates the migration of a reactant from one phase into another phase where reaction occurs.
substance with phase-transfer catalyst role
Chemical role played by a material when used to promote crystallisation.
substance with crystallisation adjutant role
An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of purine nucleoside phosphorylase (EC 2.4.2.1).
EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitors
inosine-guanosine phosphorylase inhibitor
inosine-guanosine phosphorylase inhibitors
purine deoxynucleoside phosphorylase inhibitor
purine deoxynucleoside phosphorylase inhibitors
purine deoxyribonucleoside phosphorylase inhibitor
purine deoxyribonucleoside phosphorylase inhibitors
purine nucleoside phosphorylase inhibitor
purine nucleoside phosphorylase inhibitors
purine ribonucleoside phosphorylase inhibitor
purine ribonucleoside phosphorylase inhibitors
purine-nucleoside phosphorylase (EC 2.4.2.1) inhibitor
purine-nucleoside phosphorylase (EC 2.4.2.1) inhibitors
purine-nucleoside phosphorylase inhibitor
purine-nucleoside phosphorylase inhibitors
purine-nucleoside:phosphate ribosyltransferase inhibitor
purine-nucleoside:phosphate ribosyltransferase inhibitors
substance with EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor role
An agonist that binds to and activates sphingosine 1-phosphate receptors.
sphingosine 1-phosphate receptor agonist
sphingosine 1-phosphate receptor agonists
sphingosine-1-phosphate receptor agonists
substance with sphingosine-1-phosphate receptor agonist role
Any substance that inhibits the release of insulin
substance with insulin release inhibitor role
An EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitor that interferes with the action of alcohol oxidase (EC 1.1.3.13).
EC 1.1.3.13 (alcohol oxidase) inhibitors
alcohol oxidase (EC 1.1.3.13) inhibitors
alcohol:oxygen oxidoreductase inhibitors
substance with EC 1.1.3.13 (alcohol oxidase) inhibitor role
An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of cystathionine beta-synthase (EC 4.2.1.22).
EC 4.2.1.22 (cystathionine beta-synthase) inhibitors
L-serine hydro-lyase (adding homocysteine) inhibitor
L-serine hydro-lyase (adding homocysteine) inhibitors
L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming) inhibitor
L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming) inhibitors
cystathionine beta-synthase (EC 4.2.1.22) inhibitor
cystathionine beta-synthase (EC 4.2.1.22) inhibitors
substance with EC 4.2.1.22 (cystathionine beta-synthase) inhibitor role
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of mitochondrial carnitine O-palmitoyltransferase (EC 2.3.1.21).
CPT I (outer membrane carnitine palmitoyl transferase) inhibitor
CPT I (outer membrane carnitine palmitoyl transferase) inhibitors
EC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitors
L-carnitine palmitoyltransferase inhibitor
L-carnitine palmitoyltransferase inhibitors
carnitine O-palmitoyltransferase (EC 2.3.1.21) inhibitor
carnitine O-palmitoyltransferase (EC 2.3.1.21) inhibitors
carnitine O-palmitoyltransferase inhibitor
carnitine O-palmitoyltransferase inhibitors
carnitine palmitoyltransferase II inhibitor
carnitine palmitoyltransferase II inhibitors
carnitine palmitoyltransferase inhibitor
carnitine palmitoyltransferase inhibitors
carnitine palmitoyltransferase-1 inhibitor
carnitine palmitoyltransferase-1 inhibitors
carnitine palmitoyltransferase-A inhibitor
carnitine palmitoyltransferase-A inhibitors
mitochondrial carnitine palmitoyltransferase-1 inhibitor
mitochondrial carnitine palmitoyltransferase-1 inhibitors
outer malonyl-CoA inhibitable carnitine palmitoyltransferase inhibitor
outer malonyl-CoA inhibitable carnitine palmitoyltransferase inhibitors
palmitoyl-CoA:L-carnitine O-palmitoyltransferase inhibitor
palmitoyl-CoA:L-carnitine O-palmitoyltransferase inhibitors
palmitoylcarnitine transferase inhibitor
palmitoylcarnitine transferase inhibitors
substance with EC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitor role
An inhibitor that interferes with the process of T-cell proliferation.
substance with T-cell proliferation inhibitor role
A small protein-like chain designed to mimic a peptide.
The element or compound in a reduction-oxidation (redox) reaction that donates an electron to another species.
A substance that removes electrons from another reactant in a redox reaction.
Any substance that inhibits the action of sodium-dependent Pi-transporters.
sodium-dependent inorganic phosphate cotransporter inhibitor
sodium-dependent inorganic phosphate transporter inhibitor
substance with sodium-dependent Pi-transporter inhibitor role
An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of alkaline phosphatase (EC 3.1.3.1).
EC 3.1.3.1 (alkaline phosphatase) inhibitors
alkaline phosphatase (EC 3.1.3.1) inhibitor
alkaline phosphatase (EC 3.1.3.1) inhibitors
orthophosphoric-monoester phosphohydrolase (alkaline optimum) inhibitor
orthophosphoric-monoester phosphohydrolase (alkaline optimum) inhibitors
phosphate-monoester phosphohydrolase (alkaline optimum) inhibitor
phosphate-monoester phosphohydrolase (alkaline optimum) inhibitors
substance with EC 3.1.3.1 (alkaline phosphatase) inhibitor role
An antagonist at the fibroblast growth factor receptor.
fibroblast growth factor receptor antagonists
fibroblast growth factor receptor inhibitor
fibroblast growth factor receptor inhibitors
substance with fibroblast growth factor receptor antagonist role
A substance capable of undergoing rapid and highly exothermic decomposition.
An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of Na(+)/K(+)-transporting ATPase (EC 3.6.3.9).
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitors
Na(+)/K(+)-transporting ATPase (EC 3.6.3.9) inhibitor
Na(+)/K(+)-transporting ATPase (EC 3.6.3.9) inhibitors
Na(+)/K(+)-transporting ATPase inhibitor
Na(+)/K(+)-transporting ATPase inhibitors
sodium-potassium adenosine triphosphatase inhibitor
sodium-potassium adenosine triphosphatase inhibitors
substance with EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor role
Any drug which binds to gonadotropin-releasing hormone receptors and triggers a response.
gonadotrophin releasing hormone agonists
substance with gonadotropin releasing hormone agonist role
An agonist that selectively binds to and activates a glucocorticoid receptor.
substance with glucocorticoid receptor agonist role
An antogonist that blocks chemokine receptor 5 (CCR5).
substance with chemokine receptor 5 antagonist role
An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of 4-aminobutyrate--2-oxoglutarate transaminase (EC 2.6.1.19).
4-aminobutanoate:2-oxoglutarate aminotransferase inhibitor
4-aminobutanoate:2-oxoglutarate aminotransferase inhibitors
4-aminobutyrate aminotransferase inhibitor
4-aminobutyrate aminotransferase inhibitors
4-aminobutyrate--2-ketoglutarate aminotransferase inhibitor
4-aminobutyrate--2-ketoglutarate aminotransferase inhibitors
4-aminobutyrate--2-oxoglutarate aminotransferase inhibitor
4-aminobutyrate--2-oxoglutarate aminotransferase inhibitors
4-aminobutyrate--2-oxoglutarate transaminase (EC 2.6.1.19) inhibitor
4-aminobutyrate--2-oxoglutarate transaminase (EC 2.6.1.19) inhibitors
4-aminobutyrate--2-oxoglutarate transaminase inhibitor
4-aminobutyrate--2-oxoglutarate transaminase inhibitors
4-aminobutyrate-2-oxoglutarate transaminase inhibitor
4-aminobutyrate-2-oxoglutarate transaminase inhibitors
4-aminobutyric acid 2-ketoglutaric acid aminotransferase inhibitor
4-aminobutyric acid 2-ketoglutaric acid aminotransferase inhibitors
4-aminobutyric acid aminotransferase inhibitor
4-aminobutyric acid aminotransferase inhibitors
EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitors
GABA--2-oxoglutarate aminotransferase inhibitor
GABA--2-oxoglutarate aminotransferase inhibitors
GABA--2-oxoglutarate transaminase inhibitor
GABA--2-oxoglutarate transaminase inhibitors
GABA--alpha-ketoglutarate aminotransferase inhibitors
GABA--alpha-ketoglutarate transaminase inhibitor
GABA--alpha-ketoglutarate transaminase inhibitors
GABA--alpha-ketoglutaric acid transaminase inhibitor
GABA--alpha-ketoglutaric acid transaminase inhibitors
GABA--alpha-oxoglutarate aminotransferase inhibitor
GABA--alpha-oxoglutarate aminotransferase inhibitors
GABA--oxoglutarate aminotransferase inhibitor
GABA--oxoglutarate aminotransferase inhibitors
GABA--oxoglutarate transaminase inhibitor
GABA--oxoglutarate transaminase inhibitors
aminobutyrate aminotransferase inhibitor
aminobutyrate aminotransferase inhibitors
beta-alanine aminotransferase inhibitors
beta-alanine--oxoglutarate aminotransferase inhibitor
beta-alanine--oxoglutarate aminotransferase inhibitors
beta-alanine--oxoglutarate transaminase inhibitor
beta-alanine--oxoglutarate transaminase inhibitors
gamma-amino-N-butyrate transaminase inhibitor
gamma-amino-N-butyrate transaminase inhibitors
gamma-aminobutyrate aminotransaminase inhibitor
gamma-aminobutyrate aminotransaminase inhibitors
gamma-aminobutyrate transaminase inhibitor
gamma-aminobutyrate transaminase inhibitors
gamma-aminobutyrate--alpha-ketoglutarate aminotransferase inhibitor
gamma-aminobutyrate--alpha-ketoglutarate aminotransferase inhibitors
gamma-aminobutyrate--alpha-ketoglutarate transaminase inhibitor
gamma-aminobutyrate--alpha-ketoglutarate transaminase inhibitors
gamma-aminobutyrate:alpha-oxoglutarate aminotransferase inhibitor
gamma-aminobutyrate:alpha-oxoglutarate aminotransferase inhibitors
gamma-aminobutyric acid aminotransferase inhibitor
gamma-aminobutyric acid aminotransferase inhibitors
gamma-aminobutyric acid pyruvate transaminase inhibitor
gamma-aminobutyric acid pyruvate transaminase inhibitors
gamma-aminobutyric acid transaminase inhibitor
gamma-aminobutyric acid transaminase inhibitors
gamma-aminobutyric acid--2-oxoglutarate transaminase inhibitor
gamma-aminobutyric acid--2-oxoglutarate transaminase inhibitors
gamma-aminobutyric acid--alpha-ketoglutarate transaminase inhibitor
gamma-aminobutyric acid--alpha-ketoglutarate transaminase inhibitors
gamma-aminobutyric acid--alpha-ketoglutaric acid aminotransferase inhibitor
gamma-aminobutyric acid--alpha-ketoglutaric acid aminotransferase inhibitors
gamma-aminobutyric transaminase inhibitor
gamma-aminobutyric transaminase inhibitors
glutamate--succinic semialdehyde transaminase inhibitor
glutamate--succinic semialdehyde transaminase inhibitors
substance with EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor role
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of thymidylate synthase (EC 2.1.1.45).
5,10-methylenetetrahydrofolate:dUMP C-methyltransferase inhibitor
5,10-methylenetetrahydrofolate:dUMP C-methyltransferase inhibitors
EC 2.1.1.45 (thymidylate synthase) inhibitors
methylenetetrahydrofolate:dUMP C-methyltransferase inhibitor
methylenetetrahydrofolate:dUMP C-methyltransferase inhibitors
substance with EC 2.1.1.45 (thymidylate synthase) inhibitor role
An EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor that interferes with the action of phosphoribosylglycinamide formyltransferase (EC 2.1.2.2).
10-formyltetrahydrofolate:5'-phosphoribosylglycinamide N-formyltransferase inhibitors
2-amino-N-ribosylacetamide 5'-phosphate transformylase inhibitor
5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase inhibitor
5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase inhibitors
EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitors
glycinamide ribonucleotide formyltransferase inhibitor
glycinamide ribonucleotide formyltransferase inhibitors
glycinamide ribonucleotide transformylase inhibitor
glycinamide ribonucleotide transformylase inhibitors
phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) inhibitor
phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) inhibitors
phosphoribosylglycinamide formyltransferase inhibitor
phosphoribosylglycinamide formyltransferase inhibitors
substance with EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor role
Any compound that can be used for the treatment of neurodegenerative disorders.
substance with neuroprotective agent role
An agonist that selectively binds to and activates a retinoid X receptor.
substance with retinoid X receptor agonist role
Any compound that leaves a pliable, cohesive, and continuous covering over a surface when applied to it.
substance with film-forming compound role
A sclerotherapy agent is used to treat blood vessels or blood vessel malformations (vascular malformations) and also those of the lymphatic system by injection into the vessels, which makes them shrink.
An EC 1.14.16.* (oxidoreductase acting on paired donors, reduced pteridine as one donor, incorporating 1 atom of oxygen) inhibitor that interferes with the action of tyrosine 3-monooxygenase (EC 1.14.16.2).
EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitors
L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating) inhibitor
L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating) inhibitors
tyrosine 3-monooxygenase (EC 1.14.16.2) inhibitor
tyrosine 3-monooxygenase (EC 1.14.16.2) inhibitors
substance with EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor role
An antagonist at the alpha1B-adrenoceptor.
substance with alpha1B-adrenoceptor antagonist role
substance with estrogen receptor agonist role
substance with adenosine A1 receptor antagonist role
An pathway inhibitor that inhibits the synthesis of cellulose.
substance with cellulose synthesis inhibitor role
An EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitor that blocks the action of heat shock protein 90.
An antagonist at the metabotropic glutamate receptor.
metabotropic glutamate receptor antagonists
substance with metabotropic glutamate receptor antagonist role
An agonist that selectively binds to and activates a protein kinase C receptor
substance with protein kinase C agonist role
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of fatty acid amide hydrolase (EC 3.5.1.99).
EC 3.5.1.99 (fatty acid amide hydrolase) inhibitors
arachidonoylethanolamide amidohydrolase inhibitor
arachidonoylethanolamide amidohydrolase inhibitors
fatty acid amide hydrolase (EC 3.5.1.99) inhibitor
fatty acid amide hydrolase (EC 3.5.1.99) inhibitors
fatty acylamide amidohydrolase inhibitor
fatty acylamide amidohydrolase inhibitors
substance with EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor role
Any substance which is added to food to preserve or enhance its flavour and/or appearance.
A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents.
substance with food acidity regulator role
A compound that exhibits agonist activity at the delta-opioid receptor.
substance with delta-opioid receptor agonist role
Any compound that mimics the action of incretins, gastrointestinal hormones that cause an increase in the amount of insulin released from the beta cells of the islets of Langerhans after eating, even before blood glucose levels become elevated.
An agonist that selectively binds to and activates AMPA receptors.
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor agonist
substance with AMPA receptor agonist role
An agonist that selectively binds to and activates a protein kinase G receptor.
substance with protein kinase G agonist role
An agonist that selectively binds to and activates a protein kinase receptor.
substance with protein kinase agonist role
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of protein farnesyltransferase (EC 2.5.1.58), one of the three enzymes in the prenyltransferase group.
EC 2.5.1.58 (protein farnesyltransferase) inhibitors
farnesyl-diphosphate:protein-cysteine farnesyltransferase inhibitor
farnesyl-diphosphate:protein-cysteine farnesyltransferase inhibitors
protein farnesyltransferase (EC 2.5.1.58) inhibitor
protein farnesyltransferase (EC 2.5.1.58) inhibitors
substance with EC 2.5.1.58 (protein farnesyltransferase) inhibitor role
Any protease inhibitor that restricts the action of a cysteine protease.
substance with cysteine protease inhibitor role
A histamine agonist that binds to and activates histamine H3-receptors.
A histamine agonist that binds to and activates H4-receptors.
A histamine antagonist that selectively binds to but does not activate histamine H3 receptors, thereby blocking the actions of endogenous histamine.
substance with H3-receptor antagonist role
An EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor that interferes with the action of any UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15), preventing formation of N-acetylglucosamine lipid intermediates and glycosylation of newly synthesised glycoproteins.
EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitors
N-acetylglucosamine phosphotransferase inhibitor
N-acetylglucosamine transferase inhibitors
N-acetylglucosamine-1-phosphate transferase inhibitor
N-acetylglucosamine-1-phosphate transferase inhibitors
UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase inhibitor
UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase inhibitors
UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase inhibitor
UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase inhibitors
UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase inhibitor
UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase inhibitors
UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase inhibitor
UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase inhibitors
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) inhibitor
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) inhibitors
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase inhibitor
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase inhibitors
UDP-acetylglucosamine--dolichol phosphate acetylglucosamine phosphotransferase inhibitor
UDP-acetylglucosamine--dolichol phosphate acetylglucosamine phosphotransferase inhibitors
UDP-acetylglucosamine--dolichol phosphate acetylglucosamine-1-phosphotransferase inhibitor
UDP-acetylglucosamine--dolichol phosphate acetylglucosamine-1-phosphotransferase inhibitors
chitobiosylpyrophosphoryldolichol synthase inhibitor
chitobiosylpyrophosphoryldolichol synthase inhibitors
dolichol phosphate N-acetylglucosamine-1-phosphotransferase inhibitor
dolichol phosphate N-acetylglucosamine-1-phosphotransferase inhibitors
uridine diphosphoacetylglucosamine--dolichyl phosphate acetylglucosamine-1-phosphotransferase inhibitor
uridine diphosphoacetylglucosamine--dolichyl phosphate acetylglucosamine-1-phosphotransferase inhibitors
substance with EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor role
Any chemical substance produced during the conversion of a reactant to a product.
substance with reaction intermediate role
A compound which acts as an agonist at the ATP-sensitive K+ channel.
substance with K-ATP channel agonist role
A compound used to form the matrix for MALDI (matrix-assisted laser desorption/ionization) mass spectrometry. MALDI matrix materials are crystalline compounds with a fairly low molecular weight, so as to allow facile vaporization, have strong absorption at UV or IR wavelengths (to rapidly and efficiently absorb laser irradiation), generally contain polar groups (enabling them to be used in aqueous solutions) and are frequently acidic (so assisting ionisation of the compound being studied, which is contained within the matrix material).
'matrix-assisted laser desorption/ionization' matrix material
'matrix-assisted laser desorption/ionization' matrix materials
substance with MALDI matrix material role
A neurotransmitter transporter modulator that activates glutamate transporters.
excitatory amino-acid transporter activator
excitatory amino-acid transporter activators
substance with glutamate transporter activator role
A membrane transport modulator that affects the transport of neurotransmitters.
substance with neurotransmitter transporter modulator role
A cysteine protease inhibitor which inhibits cathepsin K (EC 3.4.22.38).
substance with EC 3.4.22.38 (cathepsin K) inhibitor role
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of geranylgeranyl diphosphate synthase (EC 2.5.1.29).
(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase inhibitor
(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase inhibitors
EC 2.5.1.29 (geranylgeranyl diphosphate synthase) inhibitors
geranylgeranyl diphosphate synthase (EC 2.5.1.29) inhibitor
geranylgeranyl diphosphate synthase (EC 2.5.1.29) inhibitors
geranylgeranyl diphosphate synthase inhibitor
geranylgeranyl diphosphate synthase inhibitors
geranylgeranyl pyrophosphate synthase inhibitor
geranylgeranyl pyrophosphate synthase inhibitors
geranylgeranyl pyrophosphate synthetase inhibitor
geranylgeranyl pyrophosphate synthetase inhibitors
substance with EC 2.5.1.29 (geranylgeranyl diphosphate synthase) inhibitor role
An EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of arogenate dehydrogenase (EC 1.3.1.43).
EC 1.3.1.43 (arogenate dehydrogenase) inhibitors
L-arogenate:NAD(+) oxidoreductase (decarboxylating) inhibitor
L-arogenate:NAD(+) oxidoreductase (decarboxylating) inhibitors
L-arogenate:NAD+ oxidoreductase (decarboxylating) inhibitor
L-arogenate:NAD+ oxidoreductase (decarboxylating) inhibitors
L-arogenate:NAD+ oxidoreductase inhibitor
L-arogenate:NAD+ oxidoreductase inhibitors
arogenate dehydrogenase (EC 1.3.1.43) inhibitor
arogenate dehydrogenase (EC 1.3.1.43) inhibitors
cyclohexadienyl dehydrogenase inhibitors
substance with EC 1.3.1.43 (arogenate dehydrogenase) inhibitor role
A metabolite of plant origin (phytochemical) which acts as a source material for biosynthesis of both lignans and lignin.
An EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor that interferes with the action of glycine hydroxymethyltransferase (EC 2.1.2.1).
5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase inhibitor
5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase inhibitors
EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitors
L-serine hydroxymethyltransferase inhibitor
L-serine hydroxymethyltransferase inhibitors
glycine hydroxymethyltransferase (EC 2.1.2.1) inhibitor
glycine hydroxymethyltransferase (EC 2.1.2.1) inhibitors
glycine hydroxymethyltransferase inhibitor
glycine hydroxymethyltransferase inhibitors
serine hydroxymethyltransferase inhibitor
serine hydroxymethyltransferase inhibitors
substance with EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor role
An excitatory amino acid agonist which binds to NMDA receptors and triggers a response.
substance with NMDA receptor agonist role
A food additive which is added to flour or dough to improve baking quality and/or colour.
substance with flour treatment agent role
A toxin that accumulates in patients with chronic kidney disease.
Any glycine transporter inhibitor that interferes with the action of glycine 1 transporters.
substance with glycine transporter 1 inhibitor role
An agonist that binds to and activates glycine receptors
substance with glycine receptor agonist role
An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of thioredoxin reductase (EC 1.8.1.9).
EC 1.8.1.9 (thioredoxin reductase) inhibitors
NADPH2:oxidized thioredoxin oxidoreductase inhibitor
NADPH2:oxidized thioredoxin oxidoreductase inhibitors
thioredoxin reductase (EC 1.8.1.9) inhibitor
thioredoxin reductase (EC 1.8.1.9) inhibitors
thioredoxin reductase (NADPH) inhibitors
thioredoxin-disulfide reductase inhibitor
thioredoxin-disulfide reductase inhibitors
thioredoxin:NADP+ oxidoreductase inhibitor
thioredoxin:NADP+ oxidoreductase inhibitors
substance with EC 1.8.1.9 (thioredoxin reductase) inhibitor role
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of acyl-CoA:cholesterol acyltransferase (EC 2.3.1.26).
EC 2.3.1.26 (sterol O-acyltransferase) inhibitors
acyl coenzyme A-cholesterol-O-acyltransferase inhibitor
acyl coenzyme A-cholesterol-O-acyltransferase inhibitors
acyl-CoA:cholesterol O-acyltransferase inhibitor
acyl-CoA:cholesterol acyltransferase inhibitor
acyl-CoA:cholesterol acyltransferase inhibitors
acylcoenzyme A:cholesterol O-acyltransferase inhibitor
acylcoenzyme A:cholesterol O-acyltransferase inhibitors
sterol O-acyltransferase (EC 2.3.1.26) inhibitor
sterol O-acyltransferase (EC 2.3.1.26) inhibitors
substance with EC 2.3.1.26 (sterol O-acyltransferase) inhibitor role
A sterol O-acyltransferase inhibitor that specifically inhibits acyl-CoA:cholesterol acyltransferase 2.
acyl-CoA:cholesterol acyltransferase 2 inhibitors
substance with acyl-CoA:cholesterol acyltransferase 2 inhibitor role
An EC 3.1.4.* (phosphoric diester hydrolase) inhibitor that interferes with the action of phosphatidylinositol-specific phospholipase C (EC 3.1.4.11).
1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase inhibitor
1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase inhibitors
1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase inhibitor
1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase inhibitors
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase inhibitor
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase inhibitors
EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitors
monophosphatidylinositol phosphodiesterase inhibitor
monophosphatidylinositol phosphodiesterase inhibitors
phosphatidylinositol phospholipase C inhibitor
phosphatidylinositol phospholipase C inhibitors
phosphatidylinositol-specific phospholipase C inhibitor
phosphatidylinositol-specific phospholipase C inhibitors
phosphoinositide phospholipase C (EC 3.1.4.11) inhibitor
phosphoinositide phospholipase C (EC 3.1.4.11) inhibitors
phosphoinositide phospholipase C inhibitor
phosphoinositide phospholipase C inhibitors
triphosphoinositide phosphodiesterase inhibitor
triphosphoinositide phosphodiesterase inhibitors
substance with EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor role
The role played by a substance in enhancing the appearance or odour of the human body; a name given to the substance itself or to a component of it.
Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism.
Any compound that inhibits cell division (mitosis).
A drug used to treat or prevent infections caused by Mycobacteria, a genus of actinobacteria. Aerobic and nonmotile, members of the genus include the pathogens responsible for causing tuberculosis and leprosy.
substance with antimycobacterial drug role
An antiparasitic drug which is effective against Apicomplexan parasites in the genus Plasmodium. The genus contains over 200 species and includes those responsible for malaria.
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of diacylglycerol O-acyltransferase (EC 2.3.1.20).
1,2-diacylglycerol acyltransferase inhibitor
1,2-diacylglycerol acyltransferase inhibitors
EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitors
acyl-CoA:1,2-diacylglycerol O-acyltransferase inhibitor
acyl-CoA:1,2-diacylglycerol O-acyltransferase inhibitors
diacylglycerol O-acyltransferase (EC 2.3.1.20) inhibitor
diacylglycerol O-acyltransferase (EC 2.3.1.20) inhibitors
diacylglycerol O-acyltransferase inhibitor
diacylglycerol O-acyltransferase inhibitors
diacylglycerol acyltransferase inhibitor
diacylglycerol acyltransferase inhibitors
diglyceride O-acyltransferase inhibitors
palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase inhibitor
palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase inhibitors
substance with EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitor role
An EC 6.5.1.* (DNA/RNA repair enzymes) inhibitor that interferes with the action of DNA ligase (ATP), EC 6.5.1.1.
DNA ligase (ATP) (EC 6.5.1.1) inhibitors
EC 6.5.1.1 (DNA ligase (ATP)) inhibitors
EC 6.5.1.1 [DNA ligase (ATP)] inhibitors
deoxyribonucleic acid joinase inhibitors
deoxyribonucleic acid repair enzyme inhibitor
deoxyribonucleic acid repair enzyme inhibitors
deoxyribonucleic acid-joining enzyme inhibitor
deoxyribonucleic acid-joining enzyme inhibitors
deoxyribonucleic repair enzyme inhibitor
deoxyribonucleic repair enzyme inhibitors
deoxyribonucleic-joining enzyme inhibitor
deoxyribonucleic-joining enzyme inhibitors
polydeoxyribonucleotide synthase (ATP) inhibitor
substance with EC 6.5.1.1 [DNA ligase (ATP)] inhibitor role
An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the activity of leukocyte elastase (EC 3.4.21.37).
EC 3.4.21.37 (leukocyte elastase) inhibitors
leukocyte elastase (EC 3.4.21.37) inhibitor
leukocyte elastase (EC 3.4.21.37) inhibitors
polymorphonuclear leukocyte elastase inhibitor
polymorphonuclear leukocyte elastase inhibitors
substance with EC 3.4.21.37 (leukocyte elastase) inhibitor role
An inhibitor of hepatitis C protease, an enzyme required for production of proteins needed for viral assembly.
substance with hepatitis C protease inhibitor role
Any protease inhibitor that restricts the action of a serine protease.
substance with serine protease inhibitor role
A cysteine protease inhibitor which inhibits cathepsin B (EC 3.4.22.1).
substance with cathepsin B inhibitor role
A depigmentation agent which inhibits the synthesis of melanin.
substance with melanin synthesis inhibitor role
An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of chymotrypsin (EC 3.4.21.1).
substance with EC 3.4.21.1 (chymotrypsin) inhibitor role
An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus.
An anti-HIV agent that destroys or inhibits the replication of HIV-1, the more infective and more virulent of the two types of HIV virus.
An anti-HIV agent that destroys or inhibits the replication of HIV-2, the less infective and less virulent of the two types of HIV virus.
An antiviral agent that destroys or inhibits the replication of the hepatitis B virus.
An antiviral agent that destroys or inhibits the replication of the herpes simplex virus (also known as the human herpes virus).
An anti-HSV agent agent that destroys or inhibits the replication of herpes simplex virus-1.
An anti-HSV agent agent that destroys or inhibits the replication of herpes simplex virus-2.
An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of heparanase (EC 3.2.1.166).
heparan sulfate N-sulfo-D-glucosamine endoglucanase inhibitor
heparan sulfate N-sulfo-D-glucosamine endoglucanase inhibitors
substance with EC 3.2.1.166 (heparanase) inhibitor role
An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of chymase (EC 3.4.21.39).
skeletal muscle (SK) protease inhibitors
substance with EC 3.4.21.39 (chymase) inhibitor role
A lipoxygenase inhibitor that interferes with the action of arachidonate 5-lipoxygenase (EC 1.13.11.34).
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitors
arachidonate 5-lipoxygenase (EC 1.13.11.34) inhibitor
arachidonate 5-lipoxygenase (EC 1.13.11.34) inhibitors
arachidonic acid 5-lipoxygenase inhibitor
arachidonic acid 5-lipoxygenase inhibitors
substance with EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor role
A lipoxygenase inhibitor that interferes with the action of arachidonate 12-lipoxygenase (EC 1.13.11.31).
EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitors
arachidonate 12-lipoxygenase (EC 1.13.11.31) inhibitor
arachidonate 12-lipoxygenase (EC 1.13.11.31) inhibitors
substance with EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor role
A lipoxygenase inhibitor that interferes with the action of arachidonate 15-lipoxygenase (EC 1.13.11.33).
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitors
arachidonate 15-lipoxygenase (EC 1.13.11.33) inhibitor
arachidonate 15-lipoxygenase (EC 1.13.11.33) inhibitors
arachidonate:oxygen 15-oxidoreductase inhibitor
arachidonate:oxygen 15-oxidoreductase inhibitors
linoleic acid omega(6)-lipoxygenase inhibitor
linoleic acid omega(6)-lipoxygenase inhibitors
substance with EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor role
Any EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that inhibits the action of triacylglycerol lipase (EC 3.1.1.3).
EC 3.1.1.3 (triacylglycerol lipase) inhibitors
heparin releasable hepatic lipase inhibitor
heparin releasable hepatic lipase inhibitors
hepatic monoacylglycerol acyltransferase inhibitor
hepatic monoacylglycerol acyltransferase inhibitors
pancreatic triacylglycerol lipase inhibitor
pancreatic triacylglycerol lipase inhibitors
post-heparin plasma protamine-resistant lipase inhibitor
post-heparin plasma protamine-resistant lipase inhibitors
salt-resistant post-heparin lipase inhibitor
salt-resistant post-heparin lipase inhibitors
triacylglycerol ester hydrolase inhibitor
triacylglycerol ester hydrolase inhibitors
triacylglycerol lipase (EC 3.1.1.3) inhibitor
triacylglycerol lipase (EC 3.1.1.3) inhibitors
substance with EC 3.1.1.3 (triacylglycerol lipase) inhibitor role
Any compound that has anti-asthmatic effects.
substance with anti-asthmatic agent role
An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of arginine decarboxylase (EC 4.1.1.19).
EC 4.1.1.19 (arginine decarboxylase) inhibitors
L-arginine carboxy-lyase (agmatine-forming) inhibitor
L-arginine carboxy-lyase (agmatine-forming) inhibitors
arginine decarboxylase (EC 4.1.1.19) inhibitor
arginine decarboxylase (EC 4.1.1.19) inhibitors
substance with EC 4.1.1.19 (arginine decarboxylase) inhibitor role
An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of fructose-bisphosphatase (EC 3.1.3.11).
D-fructose-1,6-bisphosphate 1-phosphohydrolase inhibitor
D-fructose-1,6-bisphosphate 1-phosphohydrolase inhibitors
D-fructose-1,6-bisphosphate phosphatase inhibitor
D-fructose-1,6-bisphosphate phosphatase inhibitors
EC 3.1.3.11 (fructose-bisphosphatase) inhibitors
fructose 1,6-bisphosphate 1-phosphatase inhibitor
fructose 1,6-bisphosphate 1-phosphatase inhibitors
fructose 1,6-bisphosphate phosphatase inhibitor
fructose 1,6-bisphosphate phosphatase inhibitors
fructose 1,6-diphosphate phosphatase inhibitor
fructose 1,6-diphosphate phosphatase inhibitors
fructose bisphosphate phosphatase inhibitor
fructose bisphosphate phosphatase inhibitors
fructose diphosphate phosphatase inhibitor
fructose diphosphate phosphatase inhibitors
fructose-bisphosphatase (EC 3.1.3.11) inhibitor
fructose-bisphosphatase (EC 3.1.3.11) inhibitors
substance with EC 3.1.3.11 (fructose-bisphosphatase) inhibitor role
substance with adenosine A1 receptor agonist role
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of cyclopropane fatty acid synthase (EC 2.1.1.79).
EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitors
S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclising) inhibitor
S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclising) inhibitors
S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclizing) inhibitor
S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclizing) inhibitors
cyclopropane fatty acid synthase inhibitors
cyclopropane fatty acid synthetase inhibitor
cyclopropane fatty acid synthetase inhibitors
cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79) inhibitor
cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79) inhibitors
cyclopropane-fatty-acyl-phospholipid synthase inhibitor
cyclopropane-fatty-acyl-phospholipid synthase inhibitors
unsaturated-phospholipid methyltransferase inhibitor
unsaturated-phospholipid methyltransferase inhibitors
substance with EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor role
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of site-specific DNA-methyltransferase (adenine-specific), EC 2.1.1.72.
DNA adenine methyltransferase inhibitors
EC 2.1.1.72 (site-specific DNA-methyltransferase (adenine-specific)) inhibitor
EC 2.1.1.72 (site-specific DNA-methyltransferase (adenine-specific)) inhibitors
EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitors
restriction-modification system inhibitor
restriction-modification system inhibitors
site-specific DNA-methyltransferase (adenine-specific) (EC 2.1.1.72) inhibitor
site-specific DNA-methyltransferase (adenine-specific) (EC 2.1.1.72) inhibitors
site-specific DNA-methyltransferase (adenine-specific) inhibitor
site-specific DNA-methyltransferase (adenine-specific) inhibitors
substance with EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitor role
Antipsychotic drugs which can have different modes of action but which tend to be more likely than second generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements; such body movements can become permanent even after treatment has ceased.
substance with first generation antipsychotic role
Antipsychotic drugs which can have different modes of action but which tend to be less likely than first generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements.
substance with second generation antipsychotic role
An antagonist at the vascular endothelial growth factor receptor.
vascular endothelial growth factor receptor antagonists
vascular endothelial growth factor receptor inhibitor
vascular endothelial growth factor receptor inhibitors
substance with vascular endothelial growth factor receptor antagonist role
An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of thrombin (EC 3.4.21.5).
activated blood-coagulation factor II inhibitor
activated blood-coagulation factor II inhibitors
substance with EC 3.4.21.5 (thrombin) inhibitor role
An enzyme inhibitor that interferes with the action of mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase (EC 3.2.1.114), a key enzyme target in the development of anti-cancer therapies.
(1->3)-(1->6)-mannosyl-oligosaccharide alpha-D-mannohydrolase inhibitor
(1->3)-(1->6)-mannosyl-oligosaccharide alpha-D-mannohydrolase inhibitors
1,3-(1,6-)mannosyl-oligosaccharide alpha-D-mannohydrolase inhibitor
1,3-(1,6-)mannosyl-oligosaccharide alpha-D-mannohydrolase inhibitors
EC 3.2.1.114 (mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) inhibitors
GlcNAc transferase I-dependent alpha1,3[alpha1,6]mannosidase inhibitor
GlcNAc transferase I-dependent alpha1,3[alpha1,6]mannosidase inhibitors
exo-1,3-1,6-alpha-mannosidase inhibitors
mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase (EC 3.2.1.114) inhibitor
mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase (EC 3.2.1.114) inhibitors
mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase inhibitor
mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase inhibitors
substance with EC 3.2.1.114 (mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) inhibitor role
An agonist that binds to and activates liver receptor homologue-1 (LRH-1).
nuclear receptor subfamily 5 group A member 2 agonist
nuclear receptor subfamily 5 group A member 2 agonists
Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes.
A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299).
substance with antimicrobial food preservative role
A compound that inhibits the action of gamma-aminobutyric acid.
gamma-aminobutyric acid receptor antagonist
gamma-aminobutyric acid receptor antagonists
Any substance which is used to neutralise stomach acidity.
An agonist that binds to and activates erythropeotin receptors.
substance with erythropeotin receptor agonist role
An agonist that binds to and activates prostaglandin receptors.
substance with prostaglandin receptor agonist role
A membrane transport modulator that restores the chloride ion transport ability of defective cystic fibrosis transmembrane conductance regulator (CFTR) genes.
cystic fibrosis transmembrane conductance regulator potentiator
cystic fibrosis transmembrane conductance regulator potentiators
An antagonist that interferes with the action of smoothened (SMO) receptor.
substance with SMO receptor antagonist role
Any compound which can be used to treat or alleviate the symptoms of dyskinesia.
substance with antidyskinesia agent role
Any compound that improves mental functions such as cognition, memory, intelligence, motivation, attention, and concentration.
Any compound used for the treatment of eye conditions or eye diseases.
Any compound that is able to protect normal cells from the damage caused by radiation therapy.
substance with radiation protective agent role
Any compound which inhibits the postganglionic functioning of the sympathetic nervous system (SNS).
Any compound used to suppress premature labour and immature birth by suppressing uterine contractions.
An agonist that binds to and activates cannabinoid receptors.
substance with cannabinoid receptor agonist role
Any compound that has anti-inflammatory effects.
substance with anti-inflammatory agent role
A chemosterilant intended to sterilize insects.
A ryanodine receptor modulator which activates the receptor. Ryanodine receptors (RyRs) act as selective ion channels, modulating the release of calcium. Activating the receptors causes the release of calcium, so depleting internal calcium and ultimately preventing further muscle contraction.
substance with ryanodine receptor agonist role
A reagent used in the determination of the concentration of a coloured chemical element or chemical compound in solution.
substance with colorimetric reagent role
In NMR spectroscopy a reagent added to a solution to induce chemical shifts and thus simplify complex spectra.
nuclear magnetic resonance shift reagent
nuclear magnetic resonance shift reagents
An EC 3.4.24.* (metalloendopeptidase) inhibitor which interferes with the action of microbial collagenase (EC 3.4.24.3, also formerly EC 3.4.4.19 and EC 3.4.99.5).
Achromobacter iophagus collagenase inhibitor
Achromobacter iophagus collagenase inhibitors
Clostridium histolyticum collagenase inhibitor
Clostridium histolyticum collagenase inhibitors
Clostridium histolyticum proteinase A inhibitor
Clostridium histolyticum proteinase A inhibitors
EC 3.4.24.3 (microbial collagenase) inhibitors
microbial collagenase (EC 3.4.24.3) inhibitor
microbial collagenase (EC 3.4.24.3) inhibitors
substance with EC 3.4.24.3 (microbial collagenase) inhibitor role
An inhibitor that interferes with the process of gap junctional intercellular communication.
gap junctional intercellular communication inhibitors
substance with gap junctional intercellular communication inhibitor role
An agonist that selectively binds to and activates a retinoic acid receptor.
substance with retinoic acid receptor agonist role
An antogonist that interferes with the action of activator protein 1 (AP-1).
A provitamin that can be converted into vitamin A by enzymes from animal tissues.
An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of glucosylceramidase (EC 3.2.1.45).
D-glucosyl-N-acylsphingosine glucohydrolase inhibitor
D-glucosyl-N-acylsphingosine glucohydrolase inhibitors
EC 3.2.1.45 (glucosylceramidase) inhibitors
glucosphingosine glucosylhydrolase inhibitor
glucosphingosine glucosylhydrolase inhibitors
glucosylceramidase (EC 3.2.1.45) inhibitor
glucosylceramidase (EC 3.2.1.45) inhibitors
glucosylsphingosine beta-D-glucosidase inhibitor
glucosylsphingosine beta-D-glucosidase inhibitors
glucosylsphingosine beta-glucosidase inhibitor
glucosylsphingosine beta-glucosidase inhibitors
substance with EC 3.2.1.45 (glucosylceramidase) inhibitor role
An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of sucrose alpha-glucosidase (EC 3.2.1.48).
EC 3.2.1.48 (sucrose alpha-glucosidase) inhibitors
sucrose alpha-glucosidase (EC 3.2.1.48) inhibitor
sucrose alpha-glucosidase (EC 3.2.1.48) inhibitors
sucrose-alpha-D-glucohydrolase inhibitor
sucrose-alpha-D-glucohydrolase inhibitors
substance with EC 3.2.1.48 (sucrose alpha-glucosidase) inhibitor role
An EC 3.2.1.* (glycosidase) inhibitor that inhibits the action of sucrose oligo-1,6-glucosidase (EC 3.2.1.10).
EC 3.2.1.10 (oligo-1,6-glucosidase) inhibitors
dextrin 6alpha-glucanohydrolase inhibitor
dextrin 6alpha-glucanohydrolase inhibitors
oligo-1,6-glucosidase (EC 3.2.1.10) inhibitor
oligo-1,6-glucosidase (EC 3.2.1.10) inhibitors
oligosaccharide alpha-1,6-glucohydrolase inhibitor
oligosaccharide alpha-1,6-glucohydrolase inhibitors
substance with EC 3.2.1.10 (oligo-1,6-glucosidase) inhibitor role
An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of alpha-glucosidase (EC 3.2.1.20).
EC 3.2.1.20 (alpha-glucosidase) inhibitors
alpha-glucosidase (EC 3.2.1.20) inhibitor
alpha-glucosidase (EC 3.2.1.20) inhibitors
substance with EC 3.2.1.20 (alpha-glucosidase) inhibitor role
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of protein geranylgeranyltransferase type I (EC 2.5.1.59).
EC 2.5.1.59 (protein geranylgeranyltransferase type I) inhibitors
geranylgeranyl-diphosphate:protein-cysteine geranyltransferase inhibitor
geranylgeranyl-diphosphate:protein-cysteine geranyltransferase inhibitors
geranylgeranyltransferase type I inhibitor
geranylgeranyltransferase type I inhibitors
protein geranylgeranyltransferase type I (EC 2.5.1.59) inhibitor
protein geranylgeranyltransferase type I (EC 2.5.1.59) inhibitors
protein geranylgeranyltransferase type I inhibitor
protein geranylgeranyltransferase type I inhibitors
substance with EC 2.5.1.59 (protein geranylgeranyltransferase type I) inhibitor role
An inhibitor of HIV-1 integrase, an enzyme required for the integration of the genetic material of the retrovirus into the DNA of the infected cells.
substance with HIV-1 integrase inhibitor role
A protein kinase inhibitor of the mammalian target of rapamycin (mTOR), a protein that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis and transcription. mTOR inhibitors are used to prevent transplant rejection and in treatment of cancer.
mammalian target of rapamycin inhibitors
Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms.
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
A compound which causes a reduction in the levels of glutathione in cells.
substance with glutathione depleting agent role
An EC 1.3.98.* (oxidoreductase acting on CH-CH group of donors, with other, known, acceptors) inhibitor that interferes with the action of dihydroorotate oxidase (fumarate), EC 1.3.98.1 (formerly EC 1.3.3.1).
(S)-dihydroorotate:fumarate oxidoreductase inhibitor
(S)-dihydroorotate:fumarate oxidoreductase inhibitors
EC 1.3.98.1 (dihydroorotate oxidase (fumarate)) inhibitor
EC 1.3.98.1 (dihydroorotate oxidase (fumarate)) inhibitors
EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitors
dihydroorotate oxidase (fumarate) (EC 1.3.98.1) inhibitor
dihydroorotate oxidase (fumarate) (EC 1.3.98.1) inhibitors
dihydroorotate oxidase (fumarate) inhibitor
dihydroorotate oxidase (fumarate) inhibitors
substance with EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor role
A pathway inhibitor that inhibits the synthesis of pyrimidine.
substance with pyrimidine synthesis inhibitor role
An agonist that selectively binds to and activates guanylate cyclase 2C receptors.
substance with guanylate cyclase 2C agonist role
An antagonist at the bradykinin receptor.
substance with bradykinin receptor antagonist role
purinergic receptor subtype P2Y12 antagonist
purinergic receptor subtype P2Y12 antagonists
substance with P2Y12 receptor antagonist role
An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of coagulation factor Xa (EC 3.4.21.6).
EC 3.4.21.6 (coagulation factor Xa) inhibitors
activated Stuart-Prower factor inhibitor
activated Stuart-Prower factor inhibitors
activated blood-coagulation factor X inhibitor
activated blood-coagulation factor X inhibitors
coagulation factor Xa (EC 3.4.21.6) inhibitor
coagulation factor Xa (EC 3.4.21.6) inhibitors
substance with EC 3.4.21.6 (coagulation factor Xa) inhibitor role
An EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitor that specifically inhibits dipeptidyl peptidase-4 (EC 3.4.14.5).
EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitors
T cell triggering molecule Tp103 inhibitor
T cell triggering molecule Tp103 inhibitors
X-prolyl dipeptidyl aminopeptidase inhibitor
X-prolyl dipeptidyl aminopeptidase inhibitors
Xaa-Pro-dipeptidyl-aminopeptidase inhibitor
Xaa-Pro-dipeptidyl-aminopeptidase inhibitors
amino acyl-prolyl dipeptidyl aminopeptidase inhibitor
amino acyl-prolyl dipeptidyl aminopeptidase inhibitors
dipeptidyl-peptidase IV (EC 3.4.14.5) inhibitor
dipeptidyl-peptidase IV (EC 3.4.14.5) inhibitors
glycylprolyl dipeptidylaminopeptidase inhibitor
glycylprolyl dipeptidylaminopeptidase inhibitors
postproline dipeptidyl aminopeptidase IV inhibitor
postproline dipeptidyl aminopeptidase IV inhibitors
substance with EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor role
An EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of cytochrome P450 17-alpha-hydroxylase/C17,20-lyase (EC 1.14.99.9).
17-alpha-hydroxylase/C17,20-lyase inhibitor
17-alpha-hydroxylase/C17,20-lyase inhibitors
17alpha-hydroxylase-C17,20 lyase inhibitor
17alpha-hydroxylase-C17,20 lyase inhibitors
EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitors
cytochrome P450 (P-45017alpha,lyase) inhibitor
cytochrome P450 (P-45017alpha,lyase) inhibitors
cytochrome P450 17-alpha-hydroxylase/C17,20-lyase inhibitor
cytochrome P450 17-alpha-hydroxylase/C17,20-lyase inhibitors
steroid 17alpha-monooxygenase (EC 1.14.99.9) inhibitor
steroid 17alpha-monooxygenase (EC 1.14.99.9) inhibitors
steroid 17alpha-monooxygenase inhibitors
steroid 17alphahydroxylase/17,20 lyase inhibitor
steroid 17alphahydroxylase/17,20 lyase inhibitors
steroid,NADPH--hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating) inhibitor
steroid,NADPH--hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating) inhibitors
substance with EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor role
An EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitor that specifically blocks the action of phosphodiesterase IV.
substance with phosphodiesterase IV inhibitor role
A hormone agonist that binds to and activates progesterone receptors.
substance with progesterone receptor agonist role
An EC 6.4.1.* (C-C bond-forming ligase) inhibitor that interferes with the action of acetyl-CoA carboxylase (EC 6.4.1.2).
EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitors
acetyl coenzyme A carboxylase inhibitors
acetyl-CoA carboxylase (EC 6.4.1.2) inhibitor
acetyl-CoA carboxylase (EC 6.4.1.2) inhibitors
acetyl-CoA:carbon-dioxide ligase (ADP-forming) inhibitor
acetyl-CoA:carbon-dioxide ligase (ADP-forming) inhibitors
substance with EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor role
Any compound which induces a partially or terminally differentiated cell to revert to an earlier developmental stage.
substance with cell dedifferentiation agent role
substance with adenosine A3 receptor antagonist role
An EC 5.99.1.* (miscellaneous isomerase) inhibitor that interferes with the action of any of the topoisomerases (enzymes that regulate the overwinding or underwinding of DNA).
substance with topoisomerase inhibitor role
Any substance that inhibits the polymerisation of the protein actin.
substance with actin polymerisation inhibitor role
Any protein kinase inhibitor that inhibits the action of an Aurora kinase (a group of serine/threonine kinases that are essential for cell proliferation).
substance with Aurora kinase inhibitor role
Any substance which blocks the painful sensation of heat caused by capsaicin acting on the TRPV1 ion channel.
transient receptor potential cation channel subfamily V member 1 antagonist
transient receptor potential cation channel subfamily V member 1 antagonists
substance with capsaicin receptor antagonist role
Any compound which acts on the peroxisome proliferator-activated receptor.
peroxisome proliferator-activated receptor modulator
peroxisome proliferator-activated receptor modulators
A PPAR modulator which activates the peroxisome proliferator-activated receptor-alpha.
peroxisome proliferator-activated receptor-alpha agonist
peroxisome proliferator-activated receptor-alpha agonists
An EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12).
3-phosphoglyceraldehyde dehydrogenase inhibitor
3-phosphoglyceraldehyde dehydrogenase inhibitors
D-glyceraldehyde-3-phosphate:NAD(+) oxidoreductase (phosphorylating) inhibitor
D-glyceraldehyde-3-phosphate:NAD(+) oxidoreductase (phosphorylating) inhibitors
EC 1.2.1.12 (glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)) inhibitor
EC 1.2.1.12 (glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)) inhibitors
EC 1.2.1.12 [glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)] inhibitors
NAD-dependent glyceraldehyde phosphate dehydrogenase inhibitor
NAD-dependent glyceraldehyde phosphate dehydrogenase inhibitors
NADH-glyceraldehyde phosphate dehydrogenase inhibitor
NADH-glyceraldehyde phosphate dehydrogenase inhibitors
dehydrogenase, glyceraldehyde phosphate inhibitor
dehydrogenase, glyceraldehyde phosphate inhibitors
glyceraldehyde phosphate dehydrogenase (NAD) inhibitor
glyceraldehyde phosphate dehydrogenase (NAD) inhibitors
glyceraldehyde-3-P-dehydrogenase inhibitor
glyceraldehyde-3-P-dehydrogenase inhibitors
glyceraldehyde-3-phosphate dehydrogenase (NAD) inhibitor
glyceraldehyde-3-phosphate dehydrogenase (NAD) inhibitors
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12) inhibitor
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12) inhibitors
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) inhibitor
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) inhibitors
glyceraldehyde-3-phosphate dehydrogenase inhibitor
glyceraldehyde-3-phosphate dehydrogenase inhibitors
phosphoglyceraldehyde dehydrogenase inhibitor
phosphoglyceraldehyde dehydrogenase inhibitors
triosephosphate dehydrogenase inhibitors
substance with EC 1.2.1.12 [glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)] inhibitor role
An EC 3.4.22.* (cysteine endopeptidase) inhibitor which interferes with the action of cathepsin L (EC 3.4.22.15).
Aldrichina grahami cysteine proteinase inhibitor
Aldrichina grahami cysteine proteinase inhibitors
substance with cathepsin L (EC 3.4.22.15) inhibitor role
A cysteine protease inhibitor which inhibits papain (EC 3.4.22.2).
substance with EC 3.4.22.2 (papain) inhibitor role
An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania.
substance with antileishmanial agent role
Any entity used to generate reactive oxygen species.
substance with reactive oxygen species generator role
An agonist that binds to and activates G-protein-coupled receptors
substance with G-protein-coupled receptor agonist role
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonists
substance with AMPA receptor antagonist role
A hormone receptor modulator that acts as a complete or partial agonist or as an antagonist at the progesterone receptor.
substance with progesterone receptor modulator role
Any drug that has been developed specifically for treatment of a rare medical condition, the condition itself being known as an orphan disease.
Any compound that binds and activates the enzyme carbamylphosphate synthetase I.
carbamylphosphate synthetase I activators
substance with carbamylphosphate synthetase I activator role
A compound that blocks the processing of the Gag precursor protein in HIV-1 by the viral protease enzyme, leading to the formation of noninfectious, immature virus particles that are incapable of infecting other cells.
substance with HIV-1 maturation inhibitor role
A histamine agonist that binds to and activates H1-receptors.
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of N-acetylserotonin methyltransferase (EC 2.1.1.4).
EC 2.1.1.4 (acetylserotonin O-methyltransferase) inhibitors
N-acetylserotonin O-methyltransferase inhibitor
N-acetylserotonin O-methyltransferase inhibitors
N-acetylserotonin methyltransferase inhibitor
N-acetylserotonin methyltransferase inhibitors
S-adenosyl-L-methionine:N-acetylserotonin O-methyltransferase inhibitor
S-adenosyl-L-methionine:N-acetylserotonin O-methyltransferase inhibitors
acetylserotonin O-methyltransferase (EC 2.1.1.4) inhibitor
acetylserotonin O-methyltransferase (EC 2.1.1.4) inhibitors
acetylserotonin O-methyltransferase inhibitor
acetylserotonin O-methyltransferase inhibitors
acetylserotonin methyltransferase inhibitor
acetylserotonin methyltransferase inhibitors
hydroxyindole O-methyltransferase inhibitor
hydroxyindole O-methyltransferase inhibitors
hydroxyindole methyltransferase inhibitor
hydroxyindole methyltransferase inhibitors
substance with EC 2.1.1.4 (acetylserotonin O-methyltransferase) inhibitor role
An EC 3.5.1.98 (histone deacetylase) inhibitor that interferes with the action of Sir2.
An agonist that binds to and activates glucagon-like peptide-1 (GLP-1) receptors.
glucagon-like peptide-1 receptor agonists
substance with glucagon-like peptide-1 receptor agonist role
Any intra-glandular substance that acts as a precursor of a hormone, usually having minimal hormonal effect itself. Prohormones generally help in amplifying the effect of existing hormones.
An antagonist at any adenosine receptor.
substance with adenosine receptor antagonist role
An enzyme inhibitor that inhibits the action of a transferase (EC 2.*)
substance with EC 2.* (transferase) inhibitor role
A signalling molecule produced and used by bacteria participating in quorum sensing, that is, in cell-cell communication to coordinate community-wide regulation of processes such as biofilm formation, virulence, and bioluminescence in populations of bacteria. Such communication can occur both within and between different species of bacteria.
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of fatty acid synthase (EC 2.3.1.85), a multi-enzyme protein involved in fatty acid synthesis.
EC 2.3.1.85 (fatty acid synthase) inhibitors
acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) inhibitor
acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing) inhibitors
fatty acid synthase (EC 2.3.1.85) inhibitor
fatty acid synthase (EC 2.3.1.85) inhibitors
substance with EC 2.3.1.85 (fatty acid synthase) inhibitor role
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of ceramidase (EC 3.5.1.23).
N-acylsphingosine amidohydrolase inhibitor
N-acylsphingosine amidohydrolase inhibitors
glycosphingolipid ceramide deacylase inhibitor
glycosphingolipid ceramide deacylase inhibitors
substance with EC 3.5.1.23 (ceramidase) inhibitor role
A PPAR modulator which activates the peroxisome proliferator-activated receptor-gamma.
peroxisome proliferator-activated receptor-gamma agonist
peroxisome proliferator-activated receptor-gamma agonists
An insecticide that acts as a repellent to insects.
An EC 3.1.4.* (phosphoric diester hydrolase) inhibitor that blocks the action of 3',5'-cyclic-GMP phosphodiesterase (EC 3.1.4.35).
3',5'-cyclic-GMP 5'-nucleotidohydrolase inhibitor
3',5'-cyclic-GMP 5'-nucleotidohydrolase inhibitors
3',5'-cyclic-GMP phosphodiesterase (EC 3.1.4.35) inhibitor
3',5'-cyclic-GMP phosphodiesterase (EC 3.1.4.35) inhibitors
EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitors
cyclic 3',5'-GMP phosphodiesterase inhibitor
cyclic 3',5'-GMP phosphodiesterase inhibitors
cyclic guanosine 3',5'-monophosphate phosphodiesterase inhibitor
cyclic guanosine 3',5'-monophosphate phosphodiesterase inhibitors
cyclic guanosine 3',5'-phosphate phosphodiesterase inhibitor
cyclic guanosine 3',5'-phosphate phosphodiesterase inhibitors
guanosine cyclic 3',5'-phosphate phosphodiesterase inhibitor
guanosine cyclic 3',5'-phosphate phosphodiesterase inhibitors
substance with EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor role
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of peptide deformylase (EC 3.5.1.88), involved in the catalytic removal of the N-terminal formyl group of nascent proteins.
EC 3.5.1.88 (peptide deformylase) inhibitors
formyl-L-methionyl peptide amidohydrolase inhibitor
formyl-L-methionyl peptide amidohydrolase inhibitors
peptide deformylase (EC 3.5.1.88) inhibitor
peptide deformylase (EC 3.5.1.88) inhibitors
substance with EC 3.5.1.88 (peptide deformylase) inhibitor role
Any molecule shown to have the potentiality in stimulating the effect of nerve growth factor.
substance with nerve growth factor stimulator role
An inhibitor that interferes with the action of MTP.
microsomal triglyceride transfer protein inhibitor
microsomal triglyceride transfer protein inhibitors
An agonist that binds to and activates glucagon-like peptide-2 (GLP-2) receptors.
glucagon-like peptide-2 receptor agonists
substance with glucagon-like peptide-2 receptor agonist role
Any toxin secreted by bacteria, viruses, fungi or protozoa enabling them to achieve colonisation of a niche in the host, inhibit or evade the host's immune response, enter and exit cells, or obtain nutrition from the host.
A provitamin that can be converted into vitamin B1 by enzymes from animal tissues.
An inhibitor that interferes with vesicular glutamate transport.
vesicular glutamate transport inhibitors
vesicular glutamate transporter 1 inhibitor
vesicular glutamate transporter 1 inhibitors
substance with vesicular glutamate transport inhibitor role
Any compound that promotes the growth of new blood vessels from pre-existing vessels.
substance with pro-angiogenic agent role
A pheromone which is released by an organism when damaged by a predator which warns other individuals that there is a danger.
An EC 2.3.2.* (aminoacyltransferase) inhibitor that interferes with the action of protein-glutamine gamma-glutamyltransferase (EC 2.3.2.13).
EC 2.3.2.13 (protein-glutamine gamma-glutamyltransferase) inhibitors
R-glutaminyl-peptide:amine gamma-glutamyl transferase inhibitor
glutaminylpeptide gamma-glutamyltransferase inhibitor
glutaminylpeptide gamma-glutamyltransferase inhibitors
protein-glutamine gamma-glutamyltransferase (EC 2.3.2.13) inhibitor
protein-glutamine gamma-glutamyltransferase (EC 2.3.2.13) inhibitors
protein-glutamine gamma-glutamyltransferase inhibitor
protein-glutamine gamma-glutamyltransferase inhibitors
protein-glutamine:amine gamma-glutamyltransferase inhibitor
protein-glutamine:amine gamma-glutamyltransferase inhibitors
substance with EC 2.3.2.13 (protein-glutamine gamma-glutamyltransferase) inhibitor role
An agonist that binds to and activates aryl hydrocarbon receptors (AhRs).
substance with aryl hydrocarbon receptor agonist role
Any inhibitor of breast cancer resistance protein (ABCG2).
breast cancer resistance protein inhibitors
substance with breast cancer resistance protein inhibitor role
Any inhibitor of the biosynthesis of carotenoids.
substance with carotogenesis inhibitor role
An EC 1.3.99.* (oxidoreductase acting on donor CH-CH group with other acceptors) inhibitor that interferes with the action of phytoene desaturase (zeta-carotene-forming), EC 1.3.99.29, an enzyme of carotenoid biosynthesis that converts phytoene into zeta-carotene (zeta-carotene) via the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene.
15-cis-phytoene:acceptor oxidoreductase (zeta-carotene-forming) inhibitor
15-cis-phytoene:acceptor oxidoreductase (zeta-carotene-forming) inhibitors
EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitors
phytoene desaturase (zeta-carotene-forming) (EC 1.3.99.29) inhibitor
phytoene desaturase (zeta-carotene-forming) (EC 1.3.99.29) inhibitors
phytoene desaturase (zeta-carotene-forming) inhibitor
phytoene desaturase (zeta-carotene-forming) inhibitors
substance with EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitor role
An EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 atoms of oxygen) inhibitor that interferes with the action of indoleamine 2,3-dioxygenase (EC 1.13.11.52).
D-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) inhibitor
D-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) inhibitors
EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitors
indoleamine 2,3-dioxygenase (EC 1.13.11.52) inhibitor
indoleamine 2,3-dioxygenase (EC 1.13.11.52) inhibitors
substance with EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor role
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of carbonyl reductase (NADPH), EC 1.1.1.184.
EC 1.1.1.184 (carbonyl reductase (NADPH)) inhibitor
EC 1.1.1.184 (carbonyl reductase (NADPH)) inhibitors
EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitors
NADPH2-dependent carbonyl reductase inhibitor
NADPH2-dependent carbonyl reductase inhibitors
carbonyl reductase (NADPH) (EC 1.1.1.184) inhibitor
carbonyl reductase (NADPH) (EC 1.1.1.184) inhibitors
nonspecific NADPH-dependent carbonyl reductase inhibitor
nonspecific NADPH-dependent carbonyl reductase inhibitors
prostaglandin 9-ketoreductase inhibitors
secondary-alcohol:NADP+ oxidoreductase inhibitor
secondary-alcohol:NADP+ oxidoreductase inhibitors
substance with EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor role
An EC 1.11.1.* (peroxidases) inhibitor that inhibits the action of L-ascorbate peroxidase (EC 1.11.1.11).
EC 1.11.1.11 (L-ascorbate peroxidase) inhibitors
L-ascorbate peroxidase (EC 1.11.1.11) inhibitor
L-ascorbate peroxidase (EC 1.11.1.11) inhibitors
L-ascorbate:hydrogen-peroxide oxidoreductase inhibitor
L-ascorbate:hydrogen-peroxide oxidoreductase inhibitors
L-ascorbic acid-specific peroxidase inhibitor
L-ascorbic acid-specific peroxidase inhibitors
substance with EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor role
Any compound that protects plants by activating their defence mechanisms.
Any compound that inhibits one or more steps in the pathway leading to the synthesis of brassinosteroids.
substance with brassinosteroid biosynthesis inhibitor role
An agent that reduces or interferes with the mutagenic actions or effects of a substance.
An agonist that binds to and activates abscisic acid receptors.
substance with abscisic acid receptor agonist role
An EC 1.3.3.* (oxidoreductase acting on donor CH-CH group with oxygen as acceptor) inhibitor that interferes with the action of protoporphyrinogen oxidase (EC 1.3.3.4).
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitors
protoporphyrinogen IX oxidase inhibitors
protoporphyrinogen oxidase (EC 1.3.3.4) inhibitor
protoporphyrinogen oxidase (EC 1.3.3.4) inhibitors
protoporphyrinogen-IX:oxygen oxidoreductase inhibitor
protoporphyrinogen-IX:oxygen oxidoreductase inhibitors
substance with EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor role
Any compound that inhibits one or more steps in the pathway leading to the synthesis of gibberellins.
substance with gibberellin biosynthesis inhibitor role
An EC 4.4.1.* (C-S lyase) inhibitor that interferes with the action of the enzyme methionine gamma-lyase (EC 4.4.1.11).
EC 4.4.1.11 (methionine gamma-lyase) inhibitors
methionine gamma-lyase (EC 4.4.1.11) inhibitor
methionine gamma-lyase (EC 4.4.1.11) inhibitors
substance with EC 4.4.1.11 (methionine gamma-lyase) inhibitor role
An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of H(+)-transporting two-sector ATPase inhibitor (EC 3.6.3.14).
ATP phosphohydrolase (H(+)-transporting) inhibitor
ATP phosphohydrolase (H(+)-transporting) inhibitors
EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitors
H(+)-transporting two-sector ATPase (EC 3.6.3.14) inhibitor
H(+)-transporting two-sector ATPase (EC 3.6.3.14) inhibitors
H(+)-transporting two-sector ATPase inhibitor
H(+)-transporting two-sector ATPase inhibitors
bacterial Ca(2+)/Mg(2+) ATPase inhibitor
bacterial Ca(2+)/Mg(2+) ATPase inhibitors
coupling factors (Fo, F1 and CF1) inhibitor
coupling factors (Fo, F1 and CF1) inhibitors
substance with EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor role
Any hydrolase inhibitor that interferes with the action of a hydrolase which acts on acid anhydrides (EC 3.6.*.*).
EC 3.6.* (hydrolases acting on acid anhydrides) inhibitors
inhibitor of hydrolase acting on acid anhydride (EC 3.6.*)
inhibitors of hydrolase acting on acid anhydride (EC 3.6.*)
substance with EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor role
An inhibitor of NF-kappaB (nuclear factor kappa-light-chain-enhancer of activated B cells), a protein complex involved in the transcription of DNA.
nuclear factor kappa-light-chain-enhancer of activated B cells inhibitor
nuclear factor kappa-light-chain-enhancer of activated B cells inhibitors
A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 3.
substance with cyclooxygenase 3 inhibitor role
Any compound that inhibits oxidative phosphorylation.
substance with oxidative phosphorylation inhibitor role
Any inhibitor that interferes with the action of sodium-glucose transport protein subtype 2.
sodium glucose co-transporter 2 inhibitor
sodium glucose co-transporter 2 inhibitors
sodium-glucose transport protein subtype 2 inhibitors
sodium/glucose cotransporter 2 inhibitor
sodium/glucose cotransporter 2 inhibitors
substance with sodium-glucose transport protein subtype 2 inhibitor role
A hormone antagonist that inhibits the action of the peptide hormone cholecystokinin.
substance with cholecystokinin antagonist role
substance with adenosine A2A receptor agonist role
substance with adenosine receptor agonist role
An agonist at the adenosine A3 receptor.
substance with adenosine A3 receptor agonist role
An acaricide that kills mites of the genus Sarcoptes.
A hormone agonist that binds to and activates a thyroid hormone receptor.
substance with thyroid hormone agonist role
A photochemical role realized in the absorption of ultraviolet light, for example to protect skin cells from damage.
A drug used in treating and healing of wounds.
Any agent used to determine the amino-acid sequence in a polypeptide.
substance with protein-sequencing agent role
An EC 2.7.3.* (phosphotransferases with a nitrogenous group as acceptor) inhibitor that interferes with the action of creatine kinase, EC 2.7.3.2.
substance with EC 2.7.3.2 (creatine kinase) inhibitor role
Any EC 3.4.11.* (aminopeptidase) inhibitor that interferes with the action of methionyl aminopeptidase (EC 3.4.11.18).
EC 3.4.11.18 (methionyl aminopeptidase) inhibitors
methionyl aminopeptidase (EC 3.4.11.18) inhibitor
methionyl aminopeptidase (EC 3.4.11.18) inhibitors
substance with EC 3.4.11.18 (methionyl aminopeptidase) inhibitor role
Any methionyl aminopeptidase inhibitor that inhibits the action of methionyl aminopeptidase 2.
substance with methionine aminopeptidase 2 inhibitor role
An antagonist that binds to and deactivates cannabinoid receptors.
substance with cannabinoid receptor antagonist role
An antagonist that binds to and deactivates type 1 cannabinoid receptors.
substance with CB1 receptor antagonist role
An antagonist that binds to and deactivates type 2 cannabinoid receptors.
substance with CB2 receptor antagonist role
A reagent used in the determination by spectrophotometry of the concentration of a chemical element or chemical compound in solution.
substance with spectrophotometric reagent role
A substance that invokes a specific immune non-responsiveness due to its molecular form. If its molecular form is changed, a tolerogen can become an immunogen.
A reagent used to couple amino acids during artificial peptide synthesis.
substance with peptide coupling reagent role
A PPAR modulator which activates the peroxisome proliferator-activated receptor-beta/delta.
nuclear receptor subfamily 1, group C, member 2 agonist
nuclear receptor subfamily 1, group C, member 2 agonists
peroxisome proliferator-activated receptor-beta agonist
peroxisome proliferator-activated receptor-beta agonists
peroxisome proliferator-activated receptor-delta agonist
peroxisome proliferator-activated receptor-delta agonists
substance with PPARbeta/delta agonist role
Any compound that inhibits the growth of bacteria of the genus Vibrio.
An antimetabolite that impairs the action of folic acids
Any compound that binds to and activates the enzyme nitric oxide synthase (EC 1.14.13.39).
substance with nitric oxide synthase activator role
Any substance that stimulates the corneal nerves in the eves to cause tears.
Substance used to set dyes on fabrics or tissue sections by forming a coordination complex with the dye which then attaches to the fabric or tissue.
An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that inhibits the action of ribonucleoside-diphosphate reductase (EC 1.17.4.1).
2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase inhibitor
2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase inhibitors
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitors
nucleoside diphosphate reductase inhibitor
nucleoside diphosphate reductase inhibitors
ribonucleoside diphosphate reductase inhibitor
ribonucleoside diphosphate reductase inhibitors
ribonucleoside-diphosphate reductase (EC 1.17.4.1) inhibitor
ribonucleoside-diphosphate reductase (EC 1.17.4.1) inhibitors
ribonucleoside-diphosphate reductase inhibitor
ribonucleoside-diphosphate reductase inhibitors
ribonucleotide diphosphate reductase inhibitor
ribonucleotide diphosphate reductase inhibitors
substance with EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor role
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the activity of sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming), EC 1.1.1.153, which plays an important part in the biosynthesis of tetrahydrobiopterin.
7,8-dihydrobiopterin:NADP(+) oxidoreductase
7,8-dihydrobiopterin:NADP(+) oxidoreductases
EC 1.1.1.153 (sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)) inhibitor
EC 1.1.1.153 (sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)) inhibitors
EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitors
L-erythro-7,8-dihydrobiopterin:NADP(+) oxidoreductase inhibitor
L-erythro-7,8-dihydrobiopterin:NADP(+) oxidoreductase inhibitors
sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) (EC 1.1.1.153) inhibitor
sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) (EC 1.1.1.153) inhibitors
sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) inhibitor
sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) inhibitors
substance with EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor role
Any compound used as a monomer for a polymerisation process. The term is generally used in relation to industrial polymerisation processes.
substance with polymerisation monomer role
An compound that inhibits quinol oxidation sites.
substance with quinol oxidation site inhibitor role
An antagonist at the epidermal growth factor receptor.
epidermal growth factor receptor antagonists
epidermal growth factor receptor inhibitor
epidermal growth factor receptor inhibitors
substance with epidermal growth factor receptor antagonist role
Any substance which is used to reduce or control weight.
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase (EC 1.1.1.44).
6-phospho-D-gluconate dehydrogenase inhibitor
6-phospho-D-gluconate dehydrogenase inhibitors
6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating) inhibitor
6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating) inhibitors
6-phosphogluconate dehydrogenase (decarboxylating) inhibitor
6-phosphogluconate dehydrogenase (decarboxylating) inhibitors
6-phosphogluconic carboxylase inhibitors
6-phosphogluconic dehydrogenase inhibitor
6-phosphogluconic dehydrogenase inhibitors
EC 1.1.1.44 (NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase) inhibitors
NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase (EC 1.1.1.44) inhibitor
NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase (EC 1.1.1.44) inhibitors
NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase inhibitor
NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase inhibitors
phosphogluconate dehydrogenase (NADP+ -dependent, decarboxylating) inhibitor
phosphogluconate dehydrogenase (NADP+ -dependent, decarboxylating) inhibitors
phosphogluconic acid dehydrogenase inhibitor
phosphogluconic acid dehydrogenase inhibitors
substance with EC 1.1.1.44 (NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase) inhibitor role
A role borne by a molecule that acts to counteract or neutralize the deleterious effects of paracetamol (acetaminophen).
substance with antidote to paracetamol poisoning role
A role borne by a molecule that acts to counteract or neutralize the deleterious effects of curare.
substance with antidote to curare poisoning role
An EC 2.3.2.* (aminoacyltransferase) inhibitor that interferes with the action of gamma-glutamyltransferase (EC 2.3.2.2).
(5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase inhibitor
(5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase inhibitors
EC 2.3.2.2 (gamma-glutamyltransferase) inhibitors
L-gamma-glutamyl transpeptidase inhibitor
L-gamma-glutamyl transpeptidase inhibitors
alpha-glutamyl transpeptidase inhibitors
gamma-glutamyl peptidyltransferase inhibitor
gamma-glutamyl peptidyltransferase inhibitors
gamma-glutamyl transpeptidase inhibitors
gamma-glutamyltransferase (EC 2.3.2.2) inhibitor
gamma-glutamyltransferase (EC 2.3.2.2) inhibitors
substance with EC 2.3.2.2 (gamma-glutamyltransferase) inhibitor role
A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions.
A compound used as a probe during microarray analysis of oligosaccharide-protein interactions.
A reagent used in the immobilization of compounds prior to their use in microarray analysis.
substance with microarray analysis reagent role
An EC 3.4.23.* (aspartic endopeptidase) inhibitor that interferes with the activity of memapsin 2 (EC 3.4.23.46).
beta-site APP-cleaving enzyme 1 inhibitor
beta-site APP-cleaving enzyme 1 inhibitors
beta-site Alzheimer's amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor
beta-site Alzheimer's amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors
beta-site Alzheimer's amyloid precursor protein cleaving enzyme 1 inhibitor
beta-site Alzheimer's amyloid precursor protein cleaving enzyme 1 inhibitors
membrane-associated aspartic protease 2 inhibitor
membrane-associated aspartic protease 2 inhibitors
substance with EC 3.4.23.46 (memapsin 2) inhibitor role
An EC 3.1.27.* (endoribonucleases producing other than 5'-phosphomonoesters) inhibitor that interferes with the action of ribonuclease T1 (EC 3.1.27.3).
Aspergillus oryzae ribonuclease inhibitor
Aspergillus oryzae ribonuclease inhibitors
EC 3.1.27.3 (ribonuclease T1) inhibitors
ribonuclease T1 (EC 3.1.27.3) inhibitors
ribonuclease guaninenucleotido-2'-transferase (cyclising) inhibitor
ribonuclease guaninenucleotido-2'-transferase (cyclising) inhibitors
ribonuclease guaninenucleotido-2'-transferase (cyclizing) inhibitor
ribonuclease guaninenucleotido-2'-transferase (cyclizing) inhibitors
substance with EC 3.1.27.3 (ribonuclease T1) inhibitor role
A serine/threonine kinase inhibitor that specifically inhibits human mutant serine/threonine kinase (B-Raf)
human mutant serine/threonine kinase inhibitor
human mutant serine/threonine kinase inhibitors
Colourless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into coloured compounds. They are used in biochemical assays and in diagnosis as indicators, particularly in the form of enzyme substrates.
substance with chromogenic compound role
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of squalene synthase (EC 2.5.1.21).
EC 2.5.1.21 (squalene synthase) inhibitors
farnesyl-diphosphate farnesyltransferase inhibitor
farnesyl-diphosphate farnesyltransferase inhibitors
farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase inhibitor
farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase inhibitors
presqualene-diphosphate synthase inhibitor
presqualene-diphosphate synthase inhibitors
squalene synthase (EC 2.5.1.21) inhibitor
squalene synthase (EC 2.5.1.21) inhibitors
substance with EC 2.5.1.21 (squalene synthase) inhibitor role
An EC 5.4.3.* (intramolecular transferase transferring amino groups) inhibitor that interferes with the action of lysine 2,3-aminomutase (EC 5.4.3.2).
EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitors
lysine 2,3-aminomutase (EC 5.4.3.2) inhibitor
lysine 2,3-aminomutase (EC 5.4.3.2) inhibitors
substance with EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitor role
An antagonist at the insulin-like growth factor receptor 1.
insulin-like growth factor receptor 1 antagonists
substance with insulin-like growth factor receptor 1 antagonist role
Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol.
substance with ergosterol biosynthesis inhibitor role
Any substance that can induce the release of histamine from mast cells.
substance with histamine releasing agent role
A generally pharmacologically inactive substance that is formulated with the active ingredient of a medication.
Any substance that accelerates defecation. Compare with laxatives, which are substances that ease defecation (usually by softening faeces). A substance can be both a laxative and a cathartic.
A chemical additive used to toughen or harden a polymer material by cross-linking of polymer chains.
An inhibitor of peroxidases (EC 1.11.1.*) that inhibits the action of catalase (EC 1.11.1.6).
hydrogen-peroxide:hydrogen-peroxide oxidoreductase inhibitor
hydrogen-peroxide:hydrogen-peroxide oxidoreductase inhibitors
substance with EC 1.11.1.6 (catalase) inhibitor role
An EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor that interferes with the action of any of the peroxidases (EC 1.11.1.*).
substance with EC 1.11.1.* (peroxidases) inhibitor role
An agonist that binds to and activates platelet-activating factor receptors.
platelet-activating factor receptor agonists
substance with platelet-activating factor receptor agonist role
An EC 6.1.* (C-O bond-forming ligase) inhibitor that interferes with the action of any ligase forming aminoacyl tRNA and related compounds (EC 6.1.1.*).
EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitors
ligases forming aminoacyl tRNA and related compounds (EC 6.1.1.*) inhibitor
ligases forming aminoacyl tRNA and related compounds (EC 6.1.1.*) inhibitors
substance with EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor role
An EC 1.4.4.* (oxidoreductase acting on donor CH-NH2 group, a disulfide as acceptor) inhibitor that interferes with the action of glycine decarboxylase (EC 1.4.4.2).
EC 1.4.4.2 (glycine dehydrogenase (aminomethyl-transferring)) inhibitor
EC 1.4.4.2 (glycine dehydrogenase (aminomethyl-transferring)) inhibitors
EC 1.4.4.2 [glycine dehydrogenase (aminomethyl-transferring)] inhibitors
glycine cleavage system P-protein inhibitor
glycine cleavage system P-protein inhibitors
glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) inhibitor
glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) inhibitors
glycine dehydrogenase (aminomethyl-transferring) inhibitor
glycine dehydrogenase (aminomethyl-transferring) inhibitors
glycine dehydrogenase (decarboxylating) inhibitor
glycine dehydrogenase (decarboxylating) inhibitors
glycine-cleavage complex P-protein inhibitor
glycine-cleavage complex P-protein inhibitors
glycine:H-protein-lipoyllysine oxidoreductase (decarboxylating, acceptor-amino-methylating)
glycine:H-protein-lipoyllysine oxidoreductase (decarboxylating, acceptor-amino-methylating) inhibitor
glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating) inhibitor
glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating) inhibitors
substance with EC 1.4.4.2 [glycine dehydrogenase (aminomethyl-transferring)] inhibitor role
An EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor that specifically inhibits the action of seryl-tRNA synthetase (EC 6.1.1.11).
EC 6.1.1.11 (serine--tRNA ligase) inhibitor
EC 6.1.1.11 (serine--tRNA ligase) inhibitors
L-serine:tRNA(Ser) ligase (AMP-forming) inhibitor
L-serine:tRNA(Ser) ligase (AMP-forming) inhibitors
serine--tRNA ligase (EC 6.1.1.11) inhibitor
serine--tRNA ligase (EC 6.1.1.11) inhibitors
seryl-transfer RNA synthetase inhibitors
seryl-transfer ribonucleate synthetase inhibitor
seryl-transfer ribonucleate synthetase inhibitors
seryl-transfer ribonucleic acid synthetase inhibitor
seryl-transfer ribonucleic acid synthetase inhibitors
substance with EC 6.1.1.11 (serine--tRNA ligase) inhibitor role
An EC 5.1.1.* (racemases acting on amino acids and derivatives) inhibitor that interferes with the action of alanine racemase (EC 5.1.1.1).
EC 5.1.1.1 (alanine racemase) inhibitors
alanine racemase (EC 5.1.1.1) inhibitors
substance with EC 5.1.1.1 (alanine racemase) inhibitor role
An enzyme inhibitor that inhibits the action of an isomerase (EC 5.*.*.*).
substance with EC 5.* (isomerase) inhibitor role
An acid--amino-acid ligase inhibitor that inhibits the action of a D-alanine--D-alanine ligase (EC 6.3.2.4).
D-alanine--D-alanine ligase (EC 6.3.2.4) inhibitor
D-alanine--D-alanine ligase (EC 6.3.2.4) inhibitors
D-alanine:D-alanine ligase (ADP-forming) inhibitor
D-alanine:D-alanine ligase (ADP-forming) inhibitors
EC 6.3.2.4 (D-alanine--D-alanine ligase) inhibitors
alanine:alanine ligase (ADP-forming) inhibitor
alanine:alanine ligase (ADP-forming) inhibitors
substance with EC 6.3.2.4 (D-alanine--D-alanine ligase) inhibitor role
An acid--amino-acid ligase inhibitor that inhibits the action of a glutamate--cysteine ligase (EC 6.3.2.2)
EC 6.3.2.2 (glutamate--cysteine ligase) inhibitors
gamma-glutamyl-L-cysteine synthetase inhibitor
gamma-glutamyl-L-cysteine synthetase inhibitors
gamma-glutamylcysteine synthetase inhibitor
gamma-glutamylcysteine synthetase inhibitors
gamma-glutamylcysteinyl synthetase inhibitor
gamma-glutamylcysteinyl synthetase inhibitors
glutamate--cysteine ligase (EC 6.3.2.2) inhibitor
glutamate--cysteine ligase (EC 6.3.2.2) inhibitors
substance with EC 6.3.2.2 (glutamate--cysteine ligase) inhibitor role
A ligase inhibitor that interferes with the action of a C-N bond-forming ligase (EC 6.3.*.*).
C-N bond-forming ligase (EC 6.3.*) inhibitor
C-N bond-forming ligase (EC 6.3.*) inhibitors
EC 6.3.* (C-N bond-forming ligase) inhibitorS
substance with EC 6.3.* (C-N bond-forming ligase) inhibitor role
Any enzyme inhibitor that interferes with the action of a ligase (EC 6.*.*.*). Ligases are enzymes that catalyse the joining of two molecules with concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
substance with EC 6.* (ligase) inhibitor role
A ligase inhibitor that interferes with the action of a C-C bond-forming ligase (EC 6.4.*.*).
C-C bond-forming ligase (EC 6.4.*) inhibitor
C-C bond-forming ligase (EC 6.4.*) inhibitorS
EC 6.4.* (C-C bond-forming ligase) inhibitorS
substance with EC 6.4.* (C-C bond-forming ligase) inhibitor role
A ligase inhibitor which inhibits the action of a phosphoric ester bond-forming ligase (EC 6.5.*.*).
EC 6.5.* (phosphoric ester bond-forming ligase) inhibitors
phosphoric ester bond-forming ligase (EC 6.5.*) inhibitor
phosphoric ester bond-forming ligase (EC 6.5.*) inhibitors
phosphoric ester bond-forming ligase inhibitor
phosphoric ester bond-forming ligase inhibitors
substance with EC 6.5.* (phosphoric ester bond-forming ligase) inhibitor role
Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms.
substance with eukaryotic metabolite role
Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals.
Any animal metabolite produced during a metabolic reaction in mammals.
substance with mammalian metabolite role
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae).
Saccharomyces cerevisiae secondary metabolites
substance with Saccharomyces cerevisiae metabolite role
Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea.
substance with prokaryotic metabolite role
A compound which increases either the number of red cells or the amount of haemoglobin in the blood.
An enzyme inhibitor that interferes with the action of ubiquitin--protein ligase (EC 6.3.2.19).
EC 6.3.2.19 (ubiquitin--protein ligase) inhibitors
S-phase kinase-associated protein 2 inhibitor
S-phase kinase-associated protein 2 inhibitors
ubiquitin:protein-lysine N-ligase (AMP-forming) inhibitor
ubiquitin:protein-lysine N-ligase (AMP-forming) inhibitors
substance with EC 6.3.2.19 (ubiquitin--protein ligase) inhibitor role
Any compound that binds to and activates soluble guanylate cyclase (EC 4.6.1.2).
substance with soluble guanylate cyclase activator role
Any metabolite produced by metabolism of a xenobiotic compound.
substance with xenobiotic metabolite role
A non-fluorescent small compound which become fluorescent only when complexed to a fluorogen activating protein (FAP).
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the function of histone acetyltransferase (EC 2.3.1.48).
EC 2.3.1.48 (histone acetyltransferase) inhibitors
acetyl-CoA:histone acetyltransferase inhibitor
acetyl-CoA:histone acetyltransferase inhibitors
histone acetyltransferase (EC 2.3.1.48) inhibitor
histone acetyltransferase (EC 2.3.1.48) inhibitors
nucleosome-histone acetyltransferase inhibitor
nucleosome-histone acetyltransferase inhibitors
substance with EC 2.3.1.48 (histone acetyltransferase) inhibitor role
A gas in an atmosphere that absorbs and emits radiation within the thermal infrared range, so contributing to the 'greenhouse effect'.
A compressed gas or liquid with a boiling point lower than room temperature which to used to propel and dispense liquids such as deodorants, insecticides, paints, etc. from aerosol cans.
Any animal metabolite produced during a metabolic reaction in corals (marine invertebrates).
Any metabolite produced during a metabolic reaction in marine macro- and microorganisms.
substance with odorant receptor antagonist role
Any protective agent that is able to prevent damage to the kidney.
substance with nephroprotective agent role
An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that specifically blocks the action of non-specific protein-tyrosine kinase (EC 2.7.10.2).
ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific) inhibitor
ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific) inhibitors
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitors
cytoplasmic protein tyrosine kinase inhibitor
cytoplasmic protein tyrosine kinase inhibitors
non-specific protein-tyrosine kinase (EC 2.7.10.2) inhibitor
non-specific protein-tyrosine kinase (EC 2.7.10.2) inhibitors
p60c-src protein tyrosine kinase inhibitor
p60c-src protein tyrosine kinase inhibitors
substance with EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor role
A compound used to return an excited fluorophore to the ground state by transfer of energy from fluorophore to quencher without the emission of light, with the quencher being promoted to its own excited state.
substance with fluorescence quencher role
A transferase inhibitor inhibiting the action of transferase of a one-carbon-containing group (EC 2.1.*.*).
one-carbon-containing group transferase inhibitor
one-carbon-containing group transferase inhibitors
substance with EC 2.1.* (C1-transferase) inhibitor role
A transferase inhibitor interfering with the action of any transferase that transfers an aldehyde or ketone group (EC 2.2.*.*).
EC 2.2.* (aldehyde or ketone transferase) inhibitors
aldehyde or ketone transferase inhibitor
aldehyde or ketone transferase inhibitors
aldehyde/ketone transferase (EC 2.2.*) inhibitor
aldehyde/ketone transferase (EC 2.2.*) inhibitors
substance with EC 2.2.* (aldehyde or ketone transferase) inhibitor role
A transferase inhibitor that interferes with the action of an acyltransferase (EC 2.3.*.*).
substance with EC 2.3.* (acyltransferase) inhibitor role
A transferase inhibitor inhibiting the action of a glycosyltransferase (EC 2.4.*.*).
EC 2.4.* (glycosyltransferase) inhibitors
glycosyltransferase (EC 2.4.*) inhibitor
glycosyltransferase (EC 2.4.*) inhibitors
substance with EC 2.4.* (glycosyltransferase) inhibitor role
A transferase inhibitor that inhibits the transfer of an alkyl (other than methyl) or aryl group (EC 2.5.1.*).
EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitors
alkyl/aryl (non-methyl) transferase inhibitor
alkyl/aryl (non-methyl) transferase inhibitors
non-methyl alkyl/aryl transferase (EC 2.5.1.*) inhibitor
non-methyl alkyl/aryl transferase (EC 2.5.1.*) inhibitors
non-methyl alkyl/aryl transferase inhibitor
non-methyl alkyl/aryl transferase inhibitors
non-methyl-alkyl or aryl transferase inhibitor
non-methyl-alkyl or aryl transferase inhibitors
substance with EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor role
A transferase inhibitor that inhibits a nitrogenous group transferase (EC 2.6.*.*).
nitrogenous group transferase (EC 2.6.*) inhibitor
nitrogenous group transferase (EC 2.6.*) inhibitors
nitrogenous group transferase inhibitors
substance with EC 2.6.* (nitrogenous group transferase) inhibitor role
A transferase inhibitor that inhibits the action of a phosphorus-containing group transferase (EC 2.7.*.*).
EC 2.7.* (P-containing group transferase) inhibitors
EC 2.7.* (phosphorus-containing group transferase) inhibitor
EC 2.7.* (phosphorus-containing group transferase) inhibitors
phosphorus-containing group transferase (EC 2.7.*) inhibitor
phosphorus-containing group transferase (EC 2.7.*) inhibitors
phosphorus-containing group transferase inhibitor
phosphorus-containing group transferase inhibitors
substance with EC 2.7.* (P-containing group transferase) inhibitor role
A transferase inhibitor that interferes with the action of a sulfur-containing group transferase (EC 2.8.*.*).
EC 2.8.* (S-containing group transferase) inhibitor
EC 2.8.* (S-containing group transferase) inhibitors
S-containing group transferase inhibitor
S-containing group transferase inhibitors
sulfur-containing group transferase (EC 2.8.*) inhibitor
sulfur-containing group transferase (EC 2.8.*) inhibitors
sulfur-containing group transferase inhibitor
sulfur-containing group transferase inhibitors
substance with EC 2.8.* (S-containing group transferase) inhibitor role
A transferase inhibitor that interferes with the action of a selenium-containing group transferase (EC 2.9.*.*).
EC 2.9.* (Se-containing group transferase) inhibitors
Se-containing group transferase inhibitor
Se-containing group transferase inhibitors
selenium-containing group transferase (EC 2.9.*) inhibitor
selenium-containing group transferase (EC 2.9.*) inhibitors
selenium-containing group transferase inhibitor
selenium-containing group transferase inhibitors
substance with EC 2.9.* (Se-containing group transferase) inhibitor role
A transferase inhibitor that interferes with the action of a molybdenum- or tungsten-containing group transferase (EC 2.10.*.*).
EC 2.10.* (Mo- or W-containing group transferase) inhibitors
Mo- or W-containing group transferase (EC 2.10.*) inhibitor
Mo- or W-containing group transferase (EC 2.10.*) inhibitors
Mo- or W-containing group transferase inhibitor
Mo- or W-containing group transferase inhibitors
substance with EC 2.10.* (Mo- or W-containing group transferase) inhibitor role
An isomerase inhibitor interfering with the action of a racemase or epimerase (EC 5.1.*.*).
EC 5.1.* (racemase/epimerase) inhibitors
racemase and epimerase (EC 5.1*) inhibitor
racemase and epimerase (EC 5.1*) inhibitors
substance with EC 5.1.* (racemase/epimerase) inhibitor role
An isomerase inhibitor interfering with the action of a cis-trans-isomerase (EC 5.2.*.*).
EC 5.2.* (cis-trans-isomerase) inhibitors
cis-trans-isomerase (EC5.2.*) inhibitors
substance with EC 5.2.* (cis-trans-isomerase) inhibitor role
An isomerase inhibitor that interferes with the action of an intramolecular oxidoreductase (EC 5.3.*.*).
EC 5.3.* (intramolecular oxidoreductase) inhibitors
intramolecular oxidoreductase (EC 5.3.*) inhibitor
intramolecular oxidoreductase (EC 5.3.*) inhibitors
intramolecular oxidoreductase inhibitors
substance with EC 5.3.* (intramolecular oxidoreductase) inhibitor role
An isomerase inhibitor that interferes with the action of an intramolecular transferase (EC 5.4.*.*).
EC 5.4.* (intramolecular transferase) inhibitors
intramolecular transferase (EC 5.4.*) inhibitor
intramolecular transferase (EC 5.4.*) inhibitors
substance with EC 5.4.* (intramolecular transferase) inhibitor role
An isomerase inhibitor that interferes with the action of an intramolecular lyase (EC 5.5.*.*).
EC 5.5.* (intramolecular lyase) inhibitors
substance with EC 5.5.* (intramolecular lyase) inhibitor role
An isomerase inhibitor that interferes with the action of any member of the group of 'other isomerases' (EC 5.99.*.*).
EC 5.99.* (miscellaneous isomerases) inhibitor
EC 5.99.* (miscellaneous isomerases) inhibitors
substance with EC 5.99.* (other isomerases) inhibitor role
A ligase inhibitor that interferes with the action of a C-O bond-forming ligase (EC 6.1.*.*).
C-O bond-forming ligase (EC 6.1.*) inhibitor
C-O bond-forming ligase (EC 6.1.*) inhibitors
EC 6.1.* (C-O bond-forming ligase) inhibitors
substance with EC 6.1.* (C-O bond-forming ligase) inhibitor role
A ligase inhibitor that interferes with the action of a C-S bond-forming ligase (EC 6.2.*.*).
C-S bond-forming ligase (EC 6.2.*) inhibitor
C-S bond-forming ligase (EC 6.2.*) inhibitors
EC 6.2.* (C-S bond-forming ligase) inhibitors
substance with EC 6.2.* (C-S bond-forming ligase) inhibitor role
A ligase inhibitor which interferes with the action of a nitrogen-metal bond-forming ligase (EC 6.6.*.*).
EC 6.6.* (N-metal bond-forming ligase) inhibitors
N-metal bond-forming ligase (EC 6.6.*) inhibitor
N-metal bond-forming ligase (EC 6.6.*) inhibitors
substance with EC 6.6.* (N-metal bond-forming ligase) inhibitor role
An enzyme inhibitor which interferes with the action of a lyase (EC 4.*.*.*). Lyases are enzymes cleaving C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation.
substance with EC 4.* (lyase) inhibitor role
A lyase inhibitor which inhibits the action of a C-C lyase (EC 4.1.*.*).
substance with EC 4.1.* (C-C lyase) inhibitor role
A lyase inhibitor which inhibits the action of a C-O lyase (EC 4.2.*.*).
substance with EC 4.2.* (C-O lyase) inhibitor role
A lyase inhibitor which inhibits the action of a C-N lyase (EC 4.3.*.*).
substance with EC 4.3.* (C-N lyase) inhibitor role
A lyase inhibitor which inhibits the action of a C-S lyase (EC 4.4.*.*).
substance with EC 4.4.* (C-S lyase) inhibitor role
A lyase inhibitor which inhibits the action of a C-halide lyase (EC 4.5.*.*).
substance with EC 4.5.* (C-halide lyase) inhibitor role
A lyase inhibitor which inhibits the action of a P-O lyase (EC 4.6.*.*).
substance with EC 4.6.* (P-O lyase) inhibitor role
A lyase inhibitor which inhibits the action of a C-P lyase (EC 4.6.*.*).
substance with EC 4.7.* (C-P lyase) inhibitor role
A lyase inhibitor which interferes with the activity of a lyase in the EC 4.99.*.* group.
EC 4.99.* (miscellaneous lyase) inhibitors
miscellaneous lyase (EC 4.99.*) inhibitor
miscellaneous lyase (EC 4.99.*) inhibitors
substance with EC 4.99.* (miscellaneous lyase) inhibitor role
A synthetic oligonucleotide whose base sequence is complementary to a gene's messenger RNA (mRNA) and which will bind with the mRNA inactivating it.
substance with antisense oligonucleotide role
An enzyme inhibitor which interferes with the action of an oxidoreductase (EC 1.*.*.*).
substance with EC 1.* (oxidoreductase) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-OH group of donors (EC 1.1.*.*).
EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitors
inhibitor of oxidoreductase acting on CH-OH group of donor
inhibitor of oxidoreductase acting on CH-OH group of donors
inhibitors of oxidoreductase acting on CH-OH group of donor
inhibitors of oxidoreductase acting on CH-OH group of donors
oxidoreductase acting on donor CH-OH group (EC 1.1.*) inhibitor
oxidoreductase acting on donor CH-OH group (EC 1.1.*) inhibitors
oxidoreductase acting on donor CH-OH group inhibitor
oxidoreductase acting on donor CH-OH group inhibitors
substance with EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the aldehyde or oxo group of donors (EC 1.2.*.*).
EC 1.2.* (oxidoreductase acting on donor aldehyde or oxo group) inhibitor
EC 1.2.* (oxidoreductase acting on donor aldehyde or oxo group) inhibitors
EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitors
inhibitor of oxidoreductase acting on aldehyde or oxo group of donor
inhibitor of oxidoreductase acting on aldehyde or oxo group of donors
inhibitor of oxidoreductase acting on aldehyde/oxo group of donor
inhibitor of oxidoreductase acting on aldehyde/oxo group of donors
inhibitors of oxidoreductase acting on aldehyde or oxo group of donor
inhibitors of oxidoreductase acting on aldehyde or oxo group of donors
inhibitors of oxidoreductase acting on aldehyde/oxo group of donor
inhibitors of oxidoreductase acting on aldehyde/oxo group of donors
oxidoreductase acting on donor aldehyde or oxo group (EC 1.2.*) inhibitor
oxidoreductase acting on donor aldehyde or oxo group (EC 1.2.*) inhibitors
oxidoreductase acting on donor aldehyde or oxo group inhibitor
oxidoreductase acting on donor aldehyde or oxo group inhibitors
oxidoreductase acting on donor aldehyde/oxo group (EC 1.2.*) inhibitor
oxidoreductase acting on donor aldehyde/oxo group (EC 1.2.*) inhibitors
oxidoreductase acting on donor aldehyde/oxo group inhibitor
oxidoreductase acting on donor aldehyde/oxo group inhibitors
substance with EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-CH group of donors (EC 1.3.*.*).
EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitors
inhibitor of oxidoreductase acting on CH-CH group of donor
inhibitor of oxidoreductase acting on CH-CH group of donors
inhibitors of oxidoreductase acting on CH-CH group of donor
inhibitors of oxidoreductase acting on CH-CH group of donors
oxidoreductase acting on donor CH-CH group (EC 1.3.*) inhibitor
oxidoreductase acting on donor CH-CH group (EC 1.3.*) inhibitors
oxidoreductase acting on donor CH-CH group inhibitor
oxidoreductase acting on donor CH-CH group inhibitors
substance with EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-NH2 group of donors (EC 1.4.*.*).
EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor
EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitors
inhibitor of oxidoreductase acting on CH-NH2 group of donor
inhibitor of oxidoreductase acting on CH-NH2 group of donors
inhibitors of oxidoreductase acting on CH-NH2 group of donor
inhibitors of oxidoreductase acting on CH-NH2 group of donors
oxidoreductase acting on CH-NH2 group of donor inhibitor
oxidoreductase acting on CH-NH2 group of donor inhibitors
oxidoreductase acting on CH-NH2 group of donors (EC 1.4.*) inhibitor
oxidoreductase acting on CH-NH2 group of donors (EC 1.4.*) inhibitors
substance with EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-NH group of donors (EC 1.5.*.*).
EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitors
inhibitor of oxidoreductase acting on CH-NH group of donor
inhibitor of oxidoreductase acting on CH-NH group of donors
inhibitors of oxidoreductase acting on CH-NH group of donor
inhibitors of oxidoreductase acting on CH-NH group of donors
oxidoreductase acting on donor CH-NH group (EC 1.5.*) inhibitor
oxidoreductase acting on donor CH-NH group (EC 1.5.*) inhibitors
substance with EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on NADH or NADPH (EC 1.6.*.*).
EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitors
inhibitor of oxidoreductase acting on NADH or NADPH
inhibitor of oxidoreductase acting on NADH or NADPH (EC 1.6.*)
inhibitors of oxidoreductase acting on NADH or NADPH
inhibitors of oxidoreductase acting on NADH or NADPH (EC 1.6.*)
oxidoreductase acting on NADH or NADPH (EC 1.6.*) inhibitor
oxidoreductase acting on NADH or NADPH (EC 1.6.*) inhibitors
oxidoreductase acting on NADH or NADPH inhibitor
oxidoreductase acting on NADH or NADPH inhibitors
substance with EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase of class EC 1.7.*.* (acting on other nitrogenous compounds as donors).
EC 1.7.* (oxidoreductase acting on other nitrogenous compounds as donors) inhibitors
inhibitor of oxidoreductase acting on other nitrogenous compounds as donors
inhibitor of oxidoreductase acting on other nitrogenous compounds as donors (EC 1.7.*)
inhibitors of oxidoreductase acting on other nitrogenous compounds as donors
inhibitors of oxidoreductase acting on other nitrogenous compounds as donors (EC 1.7.*)
substance with EC 1.7.* (oxidoreductase acting on other nitrogenous compounds as donors) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase of class EC 1.8.*.* (acting on a sulfur group of donors).
EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitors
oxidoreductase acting on a sulfur group of donors (EC 1.8.*) inhibitor
oxidoreductase acting on a sulfur group of donors (EC 1.8.*) inhibitors
substance with EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on a heme group of donors (EC 1.9.*.*).
EC 1.9.* (oxidoreductase acting on a heme group of donors) inhibitor
EC 1.9.* (oxidoreductase acting on a heme group of donors) inhibitors
EC 1.9.* (oxidoreductase acting on donor heme group) inhibitors
oxidoreductase acting on a heme group of donors (EC 1.9.*) inhibitor
oxidoreductase acting on a heme group of donors (EC 1.9.*) inhibitors
substance with EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on diphenols and related substances as donors (EC 1.10.*.*).
EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitors
EC 1.10.* (oxidoreductases acting on diphenols and related substances as donors) inhibitor
EC 1.10.* (oxidoreductases acting on diphenols and related substances as donors) inhibitors
inhibitor of an oxidoreductase acting on diphenols and related substances as donor
inhibitor of an oxidoreductase acting on diphenols and related substances as donor (EC 1.10.*)
inhibitor of an oxidoreductase acting on diphenols and related substances as donors
inhibitors of an oxidoreductase acting on diphenols and related substances as donor
inhibitors of an oxidoreductase acting on diphenols and related substances as donor (EC 1.10.*)
inhibitors of an oxidoreductase acting on diphenols and related substances as donors
substance with EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on peroxide as donors (EC 1.11.*.*).
EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitors
EC 1.11.* (oxidoreductases acting on peroxide as donors) inhibitor
EC 1.11.* (oxidoreductases acting on peroxide as donors) inhibitors
oxidoreductase acting on peroxide as donors (EC 1.11.*) inhibitor
oxidoreductase acting on peroxide as donors (EC 1.11.*) inhibitors
oxidoreductases acting on peroxide as donors (EC 1.11.*) inhibitor
oxidoreductases acting on peroxide as donors (EC 1.11.*) inhibitors
substance with EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on hydrogen as donors (EC 1.12.*.*).
EC 1.12.* (oxidoreductase acting on hydrogen as donors) inhibitors
EC 1.12.* (oxidoreductases acting on hydrogen as donors) inhibitor
EC 1.12.* (oxidoreductases acting on hydrogen as donors) inhibitors
inhibitor of oxidoreductase acting on hydrogen as donors
inhibitor of oxidoreductase acting on hydrogen as donors (EC 1.12.*)
inhibitors of oxidoreductase acting on hydrogen as donors
inhibitors of oxidoreductase acting on hydrogen as donors (EC 1.12.*)
oxidoreductase acting on hydrogen as donors inhibitor
oxidoreductase acting on hydrogen as donors inhibitors
substance with EC 1.12.* (oxidoreductase acting on hydrogen as donors) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases), EC 1.13.*.*.
EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitors
oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) (EC 1.13.*) inhibitor
oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) (EC 1.13.*) inhibitors
oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) inhibitor
oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases) inhibitors
substance with EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on hydrogen as donors (EC 1.14.*.*).
EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitors
inhibitor of oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*)
inhibitor of oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*)
inhibitors of oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*)
inhibitors of oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*)
oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) inhibitor
oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.*) inhibitors
oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen inhibitor
oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen inhibitors
substance with EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on superoxide as acceptor (EC 1.15.*.*).
EC 1.15.* (oxidoreductase acting on superoxide as acceptor) inhibitors
inhibitor of oxidoreductase acting on superoxide as acceptor
inhibitor of oxidoreductase acting on superoxide as acceptor (EC 1.15.*)
inhibitors of oxidoreductase acting on superoxide as acceptor
inhibitors of oxidoreductase acting on superoxide as acceptor (EC 1.15.*)
oxidoreductase acting on superoxide as acceptor (EC 1.15.*) inhibitor
oxidoreductase acting on superoxide as acceptor (EC 1.15.*) inhibitors
oxidoreductase acting on superoxide as acceptor inhibitor
oxidoreductase acting on superoxide as acceptor inhibitors
substance with EC 1.15.* (oxidoreductase acting on superoxide as acceptor) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase oxidising metal ions (EC 1.16.*.*).
EC 1.16.* (oxidoreductase oxidising metal ions) inhibitors
EC 1.16.* (oxidoreductase oxidizing metal ions) inhibitor
EC 1.16.* (oxidoreductase oxidizing metal ions) inhibitors
oxidoreductase oxidising metal ions (EC 1.16.*) inhibitor
oxidoreductase oxidising metal ions (EC 1.16.*) inhibitors
oxidoreductase oxidising metal ions inhibitor
oxidoreductase oxidising metal ions inhibitors
oxidoreductase oxidizing metal ions (EC 1.16.*) inhibitor
oxidoreductase oxidizing metal ions (EC 1.16.*) inhibitors
oxidoreductase oxidizing metal ions inhibitor
oxidoreductase oxidizing metal ions inhibitors
substance with EC 1.16.* (oxidoreductase oxidising metal ions) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on CH or CH2 (EC 1.17.*.*).
EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitors
oxidoreductase acting on CH or CH2 (EC 1.17.*) inhibitor
oxidoreductase acting on CH or CH2 (EC 1.17.*) inhibitors
oxidoreductase acting on CH or CH2 inhibitor
oxidoreductase acting on CH or CH2 inhibitors
substance with EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on iron-sulfur proteins as donors (EC 1.18.*.*).
EC 1.18.* (oxidoreductase acting on Fe-S proteins as donors) inhibitors
EC 1.18.* (oxidoreductase acting on iron-sulfur proteins as donors) inhibitor
EC 1.18.* (oxidoreductase acting on iron-sulfur proteins as donors) inhibitors
inhibitor of oxidoreductase acting on Fe-S proteins as donors
inhibitor of oxidoreductase acting on iron-sulfur proteins as donors
inhibitors of oxidoreductase acting on Fe-S proteins as donors
inhibitors of oxidoreductase acting on iron-sulfur proteins as donors
inhibitors of oxidoreductases acting on iron-sulfur proteins as donors
oxidoreductase acting on Fe-S proteins as donors (EC 1.18.*) inhibitor
oxidoreductase acting on Fe-S proteins as donors (EC 1.18.*) inhibitors
oxidoreductase acting on iron-sulfur proteins as donors (EC 1.18.*) inhibitor
oxidoreductase acting on iron-sulfur proteins as donors (EC 1.18.*) inhibitors
substance with EC 1.18.* (oxidoreductase acting on Fe-S proteins as donors) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on reduced flavodoxin as donor (EC 1.19.*.*).
EC 1.19.* (oxidoreductase acting on reduced flavodoxin as donor) inhibitors
inhibitor of oxidoreductase acting on reduced flavodoxin as donor
inhibitor of oxidoreductase acting on reduced flavodoxin as donor (EC 1.19.*)
inhibitors of oxidoreductase acting on reduced flavodoxin as donor
inhibitors of oxidoreductase acting on reduced flavodoxin as donor (EC 1.19.*)
oxidoreductase acting on reduced flavodoxin as donor (EC 1.19.*) inhibitor
oxidoreductase acting on reduced flavodoxin as donor (EC 1.19.*) inhibitors
substance with EC 1.19.* (oxidoreductase acting on reduced flavodoxin as donor) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on phosphorus or arsenic in donors (EC 1.20.*.*).
EC 1.20.* (oxidoreductase acting on P or As in donors) inhibitors
EC 1.20.* (oxidoreductase acting on phosphorus or arsenic in donors) inhibitor
EC 1.20.* (oxidoreductase acting on phosphorus or arsenic in donors) inhibitors
oxidoreductase acting on P or As in donors (EC 1.20.*) inhibitor
oxidoreductase acting on P or As in donors (EC 1.20.*) inhibitors
oxidoreductase acting on phosphorus or arsenic in donors (EC 1.20.*) inhibitor
oxidoreductase acting on phosphorus or arsenic in donors (EC 1.20.*) inhibitors
substance with EC 1.20.* (oxidoreductase acting on P or As in donors) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on X-H and Y-H to form an X-Y bond (EC 1.21.*.*).
EC 1.21.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond) inhibitors
oxidoreductase acting on X-H and Y-H to form an X-Y bond (EC 1.21.*) inhibitor
oxidoreductase acting on X-H and Y-H to form an X-Y bond (EC 1.21.*) inhibitors
oxidoreductase acting on X-H and Y-H to form an X-Y bond inhibitor
oxidoreductase acting on X-H and Y-H to form an X-Y bond inhibitors
substance with EC 1.21.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on halogen in donors (EC 1.22.*.*).
EC 1.22.* (oxidoreductase acting on halogen in donors) inhibitors
inhibitor of oxidoreductase acting on halogen in donors
inhibitor of oxidoreductase acting on halogen in donors (EC 1.22.*)
inhibitors of oxidoreductase acting on halogen in donors
inhibitors of oxidoreductase acting on halogen in donors (EC 1.22.*)
oxidoreductase acting on halogen in donors (EC 1.22.*) inhibitor
oxidoreductase acting on halogen in donors (EC 1.22.*) inhibitors
substance with EC 1.22.* (oxidoreductase acting on halogen in donors) inhibitor role
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on C-O-C group as acceptor (EC 1.23.*.*).
EC 1.23.* (oxidoreductase acting on C-O-C group as acceptor) inhibitors
inhibitor of oxidoreductase acting on C-O-C group as acceptor
inhibitor of oxidoreductase acting on C-O-C group as acceptor (EC 1.23.*)
inhibitors of oxidoreductase acting on C-O-C group as acceptor
inhibitors of oxidoreductase acting on C-O-C group as acceptor (EC 1.23.*)
oxidoreductase acting on C-O-C group as acceptor (EC 1.23.*) inhibitor
oxidoreductase acting on C-O-C group as acceptor (EC 1.23.*) inhibitors
oxidoreductase acting on C-O-C group as acceptor inhibitor
oxidoreductase acting on C-O-C group as acceptor inhibitors
substance with EC 1.23.* (oxidoreductase acting on C-O-C group as acceptor) inhibitor role
An oxidoreductase inhibitor which interferes with the action of any oxidoreductase that is classified as EC 1.97.*.*, (those oxidoreductases not included in any other EC 1.* category).
EC 1.97.* (miscellaneous oxidoreductase) inhibitor
EC 1.97.* (miscellaneous oxidoreductase) inhibitors
EC 1.97.* (other oxidoreductase) inhibitors
inhibitor of 'other' oxidoreductase (EC 1.97.*)
inhibitor of miscellaneous oxidoreductase (EC 1.97.*)
inhibitors of 'other' oxidoreductase (EC 1.97.*)
inhibitors of miscellaneous oxidoreductase (EC 1.97.*)
substance with EC 1.97.* (other oxidoreductase) inhibitor role
An oxidoreductase inhibitor which interferes with the action of any oxidoreductase using H2 as reductant (EC 1.98.*.*).
EC 1.98.* (enzymes using H2 as reductant) inhibitors
inhibitor of enzymes using H2 as reductant (EC 1.98.*)
inhibitors of enzymes using H2 as reductant (EC 1.98.*)
substance with EC 1.98.* (enzymes using H2 as reductant) inhibitor role
An oxidoreductase inhibitor which interferes with the action of any oxidoreductase that is classified as EC 1.99.*.* (other oxidoreductases using O2 as oxidant).
EC 1.99.* (other oxidoreductases using O2 as oxidant) inhibitors
substance with EC 1.99.* (other oxidoreductases using O2 as oxidant) inhibitor role
Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*).
substance with EC 3.* (hydrolase) inhibitor role
A hydrolase inhibitor that interferes with the action of any ester hydrolase (EC 3.1.*.*).
substance with EC 3.1.* (ester hydrolase) inhibitor role
A hydrolase inhibitor that interferes with the action of any glycosylase (EC 3.2.*.*).
substance with EC 3.2.* (glycosylase) inhibitor role
A hydrolase inhibitor that interferes with the action of any hydrolase acting on an ether bond (EC 3.3.*.*).
EC 3.3.* (hydrolase acting on ether bond) inhibitor
EC 3.3.* (hydrolase acting on ether bond) inhibitors
substance with EC 3.3.* (ether hydrolase) inhibitor role
Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*).
EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor
EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors
EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor
EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors
EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors
substance with EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor role
Any hydrolase inhibitor that interferes with the action of a hydrolase acting on carbon-carbon bonds (EC 3.7.*.*).
EC 3.7.* (hydrolases acting on C-C bonds) inhibitors
EC 3.7.* (hydrolases acting on carbon-carbon bonds) inhibitor
EC 3.7.* (hydrolases acting on carbon-carbon bonds) inhibitors
substance with EC 3.7.* (hydrolases acting on C-C bonds) inhibitor role
Any hydrolase inhibitor that interferes with the action of a hydrolase acting on halide bonds (EC 3.8.*.*).
EC 3.8.* (hydrolases acting on halide bonds) inhibitors
hydrolases acting on halide bonds (EC 3.8.*) inhibitor
hydrolases acting on halide bonds (EC 3.8.*) inhibitors
inhibitor of hydrolases acting on halide bonds (EC 3.8.*)
inhibitors of hydrolases acting on halide bonds (EC 3.8.*)
substance with EC 3.8.* (hydrolases acting on halide bonds) inhibitor role
Any hydrolase inhibitor that interferes with the action of a hydrolase acting on phosphorus-nitrogen bonds (EC 3.9.*.*).
EC 3.9.* (hydrolases acting on P-N bonds) inhibitors
EC 3.9.* (hydrolases acting on phosphorus-nitrogen bonds) inhibitor
EC 3.9.* (hydrolases acting on phosphorus-nitrogen bonds) inhibitors
hydrolases acting on P-N bonds (EC 3.9.*) inhibitor
hydrolases acting on P-N bonds (EC 3.9.*) inhibitors
hydrolases acting on phosphorus-nitrogen bonds (EC 3.9.*) inhibitor
hydrolases acting on phosphorus-nitrogen bonds (EC 3.9.*) inhibitors
inhibitor of hydrolases acting on P-N bonds
inhibitor of hydrolases acting on P-N bonds (EC 3.9.*)
inhibitor of hydrolases acting on phosphorus-nitrogen bonds
inhibitor of hydrolases acting on phosphorus-nitrogen bonds (EC 3.9.*)
inhibitors of hydrolases acting on P-N bonds
inhibitors of hydrolases acting on P-N bonds (EC 3.9.*)
inhibitors of hydrolases acting on phosphorus-nitrogen bonds
inhibitors of hydrolases acting on phosphorus-nitrogen bonds (EC 3.9.*)
substance with EC 3.9.* (hydrolases acting on P-N bonds) inhibitor role
Any hydrolase inhibitor that interferes with the action of a hydrolase acting on sulfur-nitrogen bonds (EC 3.10.*.*).
EC 3.10.* (hydrolases acting on S-N bonds) inhibitors
EC 3.10.* (hydrolases acting on sulfur-nitrogen bonds) inhibitor
EC 3.10.* (hydrolases acting on sulfur-nitrogen bonds) inhibitors
hydrolases acting on S-N bonds (EC 3.10.*) inhibitor
hydrolases acting on S-N bonds (EC 3.10.*) inhibitors
hydrolases acting on sulfur-nitrogen bonds (EC 3.10.*) inhibitor
hydrolases acting on sulfur-nitrogen bonds (EC 3.10.*) inhibitors
inhibitor of hydrolases acting on S-N bonds
inhibitor of hydrolases acting on S-N bonds (EC 3.10.*)
inhibitor of hydrolases acting on sulfur-nitrogen bonds
inhibitor of hydrolases acting on sulfur-nitrogen bonds (EC 3.10.*)
inhibitors of hydrolases acting on S-N bonds
inhibitors of hydrolases acting on S-N bonds (EC 3.10.*)
inhibitors of hydrolases acting on sulfur-nitrogen bonds
inhibitors of hydrolases acting on sulfur-nitrogen bonds (EC 3.10.*)
substance with EC 3.10.* (hydrolases acting on S-N bonds) inhibitor role
Any hydrolase inhibitor that interferes with the action of a hydrolase acting on carbon-phosphorus bonds (EC 3.11.*.*).
EC 3.11.* (hydrolases acting on C-P bonds) inhibitors
EC 3.11.* (hydrolases acting on carbon-phosphorus bonds) inhibitor
EC 3.11.* (hydrolases acting on carbon-phosphorus bonds) inhibitors
hydrolases acting on C-P bonds (EC 3.11.*) inhibitor
hydrolases acting on C-P bonds (EC 3.11.*) inhibitors
hydrolases acting on carbon-phosphorus bonds (EC 3.11.*) inhibitor
hydrolases acting on carbon-phosphorus bonds (EC 3.11.*) inhibitors
inhibitor of hydrolases acting on C-P bonds
inhibitor of hydrolases acting on C-P bonds (EC 3.11.*)
inhibitor of hydrolases acting on carbon-phosphorus bonds
inhibitor of hydrolases acting on carbon-phosphorus bonds (EC 3.11.*)
inhibitors of hydrolases acting on C-P bonds
inhibitors of hydrolases acting on C-P bonds (EC 3.11.*)
inhibitors of hydrolases acting on carbon-phosphorus bonds
inhibitors of hydrolases acting on carbon-phosphorus bonds (EC 3.11.*)
substance with EC 3.11.* (hydrolases acting on C-P bonds) inhibitor role
Any hydrolase inhibitor that interferes with the action of a hydrolase acting on sulfur-sulfur bonds (EC 3.12.*.*).
EC 3.12.* (hydrolases acting on S-S bonds) inhibitors
EC 3.12.* (hydrolases acting on sulfur-sulfur bonds) inhibitor
EC 3.12.* (hydrolases acting on sulfur-sulfur bonds) inhibitors
hydrolases acting on S-S bonds (EC 3.12.*) inhibitor
hydrolases acting on S-S bonds (EC 3.12.*) inhibitors
hydrolases acting on S-S bonds inhibitor
hydrolases acting on S-S bonds inhibitors
hydrolases acting on sulfur-sulfur bonds (EC 3.12.*) inhibitor
hydrolases acting on sulfur-sulfur bonds (EC 3.12.*) inhibitors
hydrolases acting on sulfur-sulfur bonds inhibitor
hydrolases acting on sulfur-sulfur bonds inhibitors
substance with EC 3.12.* (hydrolases acting on S-S bonds) inhibitor role
Any hydrolase inhibitor that interferes with the action of a hydrolase acting on carbon-sulfur bonds (EC 3.13.*.*).
EC 3.13.* (hydrolases acting on C-S bonds) inhibitors
EC 3.13.* (hydrolases acting on carbon-sulfur bonds) inhibitor
EC 3.13.* (hydrolases acting on carbon-sulfur bonds) inhibitors
hydrolases acting on C-S bonds (EC 3.13.*) inhibitor
hydrolases acting on C-S bonds (EC 3.13.*) inhibitors
hydrolases acting on C-S bonds inhibitor
hydrolases acting on C-S bonds inhibitors
hydrolases acting on carbon-sulfur bonds (EC 3.13.*) inhibitor
hydrolases acting on carbon-sulfur bonds (EC 3.13.*) inhibitors
hydrolases acting on carbon-sulfur bonds inhibitor
hydrolases acting on carbon-sulfur bonds inhibitors
substance with EC 3.13.* (hydrolases acting on C-S bonds) inhibitor role
An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a carboxylic ester hydrolase (EC 3.1.1.*).
EC 3.1.1.* (carboxylic ester hydrolase) inhibitors
carboxylic ester hydrolase (EC 3.1.1.*) inhibitor
carboxylic ester hydrolase (EC 3.1.1.*) inhibitors
substance with EC 3.1.1.* (carboxylic ester hydrolase) inhibitor role
An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of any phosphoric monoester hydrolase (EC 3.1.3.*).
EC 3.1.3.* (phosphoric monoester hydrolase) inhibitors
inhibitor of phosphoric monoester hydrolase
inhibitor of phosphoric monoester hydrolase (EC 3.1.3.*)
inhibitors of phosphoric monoester hydrolase
inhibitors of phosphoric monoester hydrolase (EC 3.1.3.*)
phosphoric monoester hydrolase (EC 3.1.3.*) inhibitor
phosphoric monoester hydrolase (EC 3.1.3.*) inhibitors
phosphoric monoester hydrolase inhibitor
phosphoric monoester hydrolase inhibitors
substance with EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor role
Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of prolyl oligopeptidase (EC 3.4.21.26).
EC 3.4.21.26 (prolyl oligopeptidase) inhibitors
proline-specific endopeptidase inhibitor
proline-specific endopeptidase inhibitors
prolyl oligopeptidase (EC 3.4.21.26) inhibitor
prolyl oligopeptidase (EC 3.4.21.26) inhibitors
substance with EC 3.4.21.26 (prolyl oligopeptidase) inhibitor role
Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of a peptidyl dipeptidase (EC 3.4.15.*).
EC 3.4.15.* (peptidyl-dipeptidase) inhibitors
inhibitor of peptidyl-dipeptidases (EC 3.4.15.*)
inhibitors of peptidyl-dipeptidases (EC 3.4.15.*)
peptidyl-dipeptidase (EC 3.4.15.*) inhibitor
peptidyl-dipeptidase (EC 3.4.15.*) inhibitors
substance with EC 3.4.15.* (peptidyl-dipeptidase) inhibitor role
An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of any endoribonuclease producing 5'-phosphomonoesters (EC 3.1.26.*).
EC 3.1.26.* (endoribonucleases producing 5'-phosphomonoesters) inhibitors
endoribonuclease producing 5'-phosphomonoesters (EC 3.1.26.*) inhibitor
endoribonuclease producing 5'-phosphomonoesters (EC 3.1.26.*) inhibitors
endoribonuclease producing 5'-phosphomonoesters inhibitor
endoribonuclease producing 5'-phosphomonoesters inhibitors
substance with EC 3.1.26.* (endoribonucleases producing 5'-phosphomonoesters) inhibitor role
An EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes wtih the action of any aminopeptidase (EC 3.4.11.*).
substance with EC 3.4.11.* (aminopeptidase) inhibitor role
An EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of any dipeptidyl- and tripeptidyl-peptidase (EC 3.4.14.*).
EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitors
EC 3.4.14.*(dipeptidyl-peptidases and tripeptidyl-peptidases) inhibitor
EC 3.4.14.*(dipeptidyl-peptidases and tripeptidyl-peptidases) inhibitors
dipeptidyl- and tripeptidyl-peptidase (EC 3.4.14.*) inhibitor
dipeptidyl- and tripeptidyl-peptidase (EC 3.4.14.*) inhibitors
dipeptidyl- and tripeptidyl-peptidase inhibitor
dipeptidyl- and tripeptidyl-peptidase inhibitors
dipeptidyl- and tripeptidyl-peptidases (EC 3.4.14.*) inhibitor
dipeptidyl- and tripeptidyl-peptidases (EC 3.4.14.*) inhibitors
dipeptidyl- and tripeptidyl-peptidases inhibitor
dipeptidyl- and tripeptidyl-peptidases inhibitors
dipeptidyl-peptidases and tripeptidyl-peptidases (EC 3.4.14.*) inhibitor
dipeptidyl-peptidases and tripeptidyl-peptidases (EC 3.4.14.*) inhibitors
substance with EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitor role
An EC 2.4.* (glycosyltransferase) inhibitor that interferes with the action of any hexosyltransferase (EC 2.4.1.*).
EC 2.4.1.* (hexosyltransferase) inhibitors
hexosyltransferase (EC 2.4.1.*) inhibitor
hexosyltransferase (EC 2.4.1.*) inhibitors
substance with EC 2.4.1.* (hexosyltransferase) inhibitor role
An EC 2.4.* (glycosyltransferase) inhibitor that interferes with the action of any pentosyltransferase (EC 2.4.2.*).
EC 2.4.2.* (pentosyltransferase) inhibitors
pentosyltransferase (EC 2.4.2.*) inhibitor
pentosyltransferase (EC 2.4.2.*) inhibitors
substance with EC 2.4.2.* (pentosyltransferase) inhibitor role
An EC 3.1.* (ester hydrolase) inhibitor that interferes with the activity of any endoribonuclease producing other than a 5'-phosphomonoesters (EC 3.1.27.*).
EC 3.1.27.* (endoribonucleases producing other than 5'-phosphomonoesters) inhibitors
inhibitor of endoribonucleases producing other than 5'-phosphomonoesters
inhibitor of endoribonucleases producing other than 5'-phosphomonoesters (EC 3.1.27.*)
inhibitors of endoribonucleases producing other than 5'-phosphomonoesters
inhibitors of endoribonucleases producing other than 5'-phosphomonoesters (EC 3.1.27.*)
substance with EC 3.1.27.* (endoribonucleases producing other than 5'-phosphomonoesters) inhibitor role
Any EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the activity of caspase-1 (EC 3.4.22.36).
interleukin 1 converting enzyme inhibitor
interleukin 1 converting enzyme inhibitors
interleukin 1beta converting enzyme inhibitor
interleukin 1beta converting enzyme inhibitors
interleukin 1beta precursor proteinase inhibitor
interleukin 1beta precursor proteinase inhibitors
interleukin 1beta-converting endopeptidase inhibitor
interleukin 1beta-converting endopeptidase inhibitors
interleukin 1beta-converting enzyme inhibitor
interleukin 1beta-converting enzyme inhibitors
interleukin-1 beta convertase precursor inhibitor
interleukin-1 beta convertase precursor inhibitors
interleukin-1beta converting enzyme inhibitor
interleukin-1beta converting enzyme inhibitors
interleukin-1beta precursor proteinase inhibitor
interleukin-1beta precursor proteinase inhibitors
precursor interleukin-1beta converting enzyme inhibitor
precursor interleukin-1beta converting enzyme inhibitors
pro-interleukin 1beta proteinase inhibitor
pro-interleukin 1beta proteinase inhibitors
prointerleukin 1beta protease inhibitors
substance with EC 3.4.22.36 (caspase-1) inhibitor role
An EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the action of any cysteine endopeptidase (EC 3.4.22.*).
EC 3.4.22.* (cysteine endopeptidase) inhibitors
cysteine endopeptidase (EC 3.4.22.*) inhibitor
cysteine endopeptidase (EC 3.4.22.*) inhibitors
substance with EC 3.4.22.* (cysteine endopeptidase) inhibitor role
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of a glutathione transferase (EC 2.5.1.18).
EC 2.5.1.18 (glutathione transferase) inhibitors
S-(hydroxyalkyl)glutathione lyase inhibitor
S-(hydroxyalkyl)glutathione lyase inhibitors
glutathione S-alkyl transferase inhibitor
glutathione S-alkyl transferase inhibitors
glutathione S-alkyltransferase inhibitor
glutathione S-alkyltransferase inhibitors
glutathione S-aralkyltransferase inhibitor
glutathione S-aralkyltransferase inhibitors
glutathione S-aryltransferase inhibitors
glutathione transferase (EC 2.5.1.18) inhibitor
glutathione transferase (EC 2.5.1.18) inhibitors
substance with EC 2.5.1.18 (glutathione transferase) inhibitor role
An EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced iron-sulfur protein as one donor, incorporating 1 atom of oxygen) inhibitor that interferes with the action of steroid 11beta-monooxygenase (EC 1.14.15.4).
EC 1.14.15.4 (steroid 11beta-monooxygenase) inhibitors
steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor
steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitors
steroid 11beta/18-hydroxylase inhibitors
steroid,reduced-adrenodoxin:oxygen oxidoreductase (11beta-hydroxylating) inhibitor
steroid,reduced-adrenodoxin:oxygen oxidoreductase (11beta-hydroxylating) inhibitors
substance with EC 1.14.15.4 (steroid 11beta-monooxygenase) inhibitor role
An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*).
EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors
non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor
non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors
substance with EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor role
An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide cyclic amide C-N hydrolase (EC 3.5.2.*).
EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitors
non-peptide cyclic amide C-N hydrolase (EC 3.5.2.*) inhibitor
non-peptide cyclic amide C-N hydrolase (EC 3.5.2.*) inhibitors
non-peptide cyclic amide C-N hydrolase inhibitor
non-peptide cyclic amide C-N hydrolase inhibitors
substance with EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor role
An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide cyclic amidine C-N hydrolase (EC 3.5.4.*).
EC 3.5.4.* (non-peptide cyclic amidine C-N hydrolase) inhibitors
non-peptide cyclic amidine C-N hydrolase (EC 3.5.4.*) inhibitor
non-peptide cyclic amidine C-N hydrolase (EC 3.5.4.*) inhibitors
non-peptide cyclic amidine C-N hydrolase inhibitor
non-peptide cyclic amidine C-N hydrolase inhibitors
substance with EC 3.5.4.* (non-peptide cyclic amidine C-N hydrolase) inhibitor role
An EC 3.1.4.* (phosphoric diester hydrolase) inhibitor that interferes with the action of sphingomyelin phosphodiesterase (EC 3.1.4.12).
EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitors
sphingomyelin cholinephosphohydrolase inhibitor
sphingomyelin cholinephosphohydrolase inhibitors
sphingomyelin phosphodiesterase (EC 3.1.4.12) inhibitor
sphingomyelin phosphodiesterase (EC 3.1.4.12) inhibitors
sphingomyelin phosphodiesterase inhibitor
sphingomyelin phosphodiesterase inhibitors
substance with EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor role
An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any protein-serine/threonine kinase (EC 2.7.11.*).
EC 2.7.11.* (protein-serine/threonine kinase) inhibitors
protein-serine/threonine kinase (EC 2.7.11.*) inhibitor
protein-serine/threonine kinase (EC 2.7.11.*) inhibitors
protein-serine/threonine kinase inhibitor
substance with EC 2.7.11.* (protein-serine/threonine kinase) inhibitor role
An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any nucleotidyltransferase (EC 2.7.7.*).
EC 2.7.7.* (nucleotidyltransferase) inhibitors
inhibitor of nucleotidyltransferases (EC 2.7.7.*)
inhibitors of nucleotidyltransferases (EC 2.7.7.*)
nucleotidyltransferase (EC 2.7.7.*) inhibitor
nucleotidyltransferase (EC 2.7.7.*) inhibitors
substance with EC 2.7.7.* (nucleotidyltransferase) inhibitor role
An EC 2.7.* (P-containing group transferase) inhibitor that interferes with any enzyme in the EC 2.7.8.* (transferases for other substituted phosphate groups) category.
EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitors
substance with EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor role
An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any protein-tyrosine kinase (EC 2.7.10.*).
EC 2.7.10.* (protein-tyrosine kinase) inhibitors
protein-tyrosine kinase (EC 2.7.10.*) inhibitor
protein-tyrosine kinase (EC 2.7.10.*) inhibitors
substance with EC 2.7.10.* (protein-tyrosine kinase) inhibitor role
An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any phosphotransferases with a nitrogenous group as acceptor (EC 2.7.3.*).
EC 2.7.3.* (phosphotransferases with a nitrogenous group as acceptor) inhibitors
phosphotransferases with a nitrogenous group as acceptor (EC 2.7.3.*) inhibitor
phosphotransferases with a nitrogenous group as acceptor (EC 2.7.3.*) inhibitors
substance with EC 2.7.3.* (phosphotransferases with a nitrogenous group as acceptor) inhibitor role
An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of beta-glucuronidase (EC 3.2.1.31).
EC 3.2.1.31 (beta-glucuronidase) inhibitors
beta-D-glucuronoside glucuronosohydrolase inhibitor
beta-D-glucuronoside glucuronosohydrolase inhibitors
beta-glucuronidase (EC 3.2.1.31) inhibitor
beta-glucuronidase (EC 3.2.1.31) inhibitors
beta-glucuronide glucuronohydrolase inhibitor
beta-glucuronide glucuronohydrolase inhibitors
substance with EC 3.2.1.31 (beta-glucuronidase) inhibitor role
An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of any acid-ammonia (or amine) ligase (EC 6.3.1.*).
EC 6.3.1.* (acid-ammonia/amine ligase) inhibitors
acid-ammonia (or amine) ligase inhibitor
acid-ammonia (or amine) ligase inhibitors
substance with EC 6.3.1.* (acid-ammonia/amine ligase) inhibitor role
An EC 6.4.* (C-C bond-forming ligase) inhibitor that interferes with the action of a carboxylating enzyme (EC 6.4.1.*).
EC 6.4.1.* (C-C bond forming ligase) inhibitor
EC 6.4.1.* (C-C bond forming ligase) inhibitors
EC 6.4.1.* (C-C bond-forming ligase) inhibitors
inhibitor of ligases forming C-C bonds (EC 6.4.1.*)
inhibitors of ligases forming C-C bonds (EC 6.4.1.*)
substance with EC 6.4.1.* (carboxylase) inhibitor role
An EC 6.5.* (phosphoric ester bond-forming ligase) inhibitor that inhibits the activity of and DNA or RNA repair enzyme (EC 6.5.1.*).
EC 6.5.1.* (DNA/RNA repair enzymes) inhibitors
substance with EC 6.5.1.* (DNA/RNA repair enzymes) inhibitor role
An EC 5.1.* (racemase/epimerase) inhibitor that interferes with the function of any racemase acting on amino acids or their derivatives (EC 5.1.1.*).
EC 5.1.1.* (racemases acting on amino acids and derivatives) inhibitors
inhibitor of racemases acting on amino acids and derivatives
inhibitor of racemases acting on amino acids and derivatives (EC 5.1.1.*)
inhibitors of racemases acting on amino acids and derivatives
inhibitors of racemases acting on amino acids and derivatives (EC 5.1.1.*)
substance with EC 5.1.1.* (racemases acting on amino acids and derivatives) inhibitor role
An EC 5.4.* (intramolecular transferase) inhibitor that interferes with the activity of any intramolecular transferase transferring amino groups (EC 5.4.3.*).
EC 5.4.3.* (intramolecular transferase transferring amino groups) inhibitors
inhibitor of intramolecular transferase transferring amino groups
inhibitor of intramolecular transferase transferring amino groups (EC 5.4.3.*)
inhibitors of intramolecular transferase transferring amino groups
inhibitors of intramolecular transferase transferring amino groups (EC 5.4.3.*)
substance with EC 5.4.3.* (intramolecular transferase transferring amino groups) inhibitor role
An EC 5.99.* (other isomerases) inhibitor that interferes with the activity of any enzyme in the EC 5.99.1.* class.
EC 5.99.1.* (miscellaneous isomerase) inhibitors
substance with EC 5.99.1.* (miscellaneous isomerase) inhibitor role
An EC 4.4.* (C-S lyase) inhibitor that interferes with the activity of any enzyme in the EC 4.4.1.* category.
substance with EC 4.4.1.* (C-S lyase) inhibitor role
An EC 4.3.* (C-N lyase) inhibitor that interferes with the action of any ammonia-lyase (EC 4.3.1.*).
substance with EC 4.3.1.* (ammonia-lyase) inhibitor role
An EC 2.5.* (transferase) inhibitor that inhibits the action of any transferase that transfers an alkyl (other than methyl) or aryl group (EC 2.5.*).
EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitors
non-methyl-alkyl or aryl transferase (EC 2.5.*) inhibitor
non-methyl-alkyl or aryl transferase (EC 2.5.*) inhibitors
substance with EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitor role
An EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor that uses NAD(+) or NADP(+) as acceptor (EC 1.1.1.*).
EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+)acceptor) inhibitors
oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor (EC 1.1.1.*) inhibitor
oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor (EC 1.1.1.*) inhibitors
substance with EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor role
An EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.1.3.*).
EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitors
oxidoreductase acting on donor CH-OH group, oxygen as acceptor (EC 1.1.3.*) inhibitor
oxidoreductase acting on donor CH-OH group, oxygen as acceptor (EC 1.1.3.*) inhibitors
substance with EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitor role
An EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor that inhibits the action of any oxidoreductase incorporating 2 atoms of oxygen (EC 1.13.11.*).
EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitors
EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 atoms of oxygen) inhibitor
EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 atoms of oxygen) inhibitors
oxidoreductase acting on single donors and incorporating 2 atoms of oxygen (EC 1.13.11.*) inhibitor
oxidoreductase acting on single donors and incorporating 2 atoms of oxygen (EC 1.13.11.*) inhibitors
substance with EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor role
An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using reduced flavin or flavoprotein as donor (EC 1.14.14.*).
EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitors
EC 1.14.14.* (oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor
EC 1.14.14.* (oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitors
oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor (EC 1.14.14.*) inhibitor
oxidoreductase acting on paired donors, with incorporation of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor (EC 1.14.14.*) inhibitors
substance with EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor role
An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any enzyme in the EC 1.14.99.* (miscellaneous) category.
EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitors
miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.99.*) inhibitor
miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen (EC 1.14.99.*) inhibitors
substance with EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor role
An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using NADH or NADPH as one donor (EC 1.14.13.*).
EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitors
oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor (EC 1.14.13.*) inhibitor
oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor (EC 1.14.13.*) inhibitors
substance with EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor role
An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme with reduced iron-sulfur protein as one donor and incorporating one atom of oxygen (EC 1.14.15.*).
EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced Fe-S protein as one donor, incorporating 1 O atom) inhibitors
EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced iron-sulfur protein as one donor, incorporating 1 atom of oxygen) inhibitor
EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced iron-sulfur protein as one donor, incorporating 1 atom of oxygen) inhibitors
oxidoreductase acting on paired donors, with reduced iron-sulfur protein as one donor, incorporating 1 atom of oxygen (EC 1.14.15.*) inhibitor
oxidoreductase acting on paired donors, with reduced iron-sulfur protein as one donor, incorporating 1 atom of oxygen (EC 1.14.15.*) inhibitors
substance with EC 1.14.15.* (oxidoreductase acting on paired donors, with reduced Fe-S protein as one donor, incorporating 1 O atom) inhibitor role
An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme using a miscellaneous compound as one donor and incorporating one atom of oxygen (EC 1.14.18.*).
EC 1.14.18.* (oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen) inhibitors
oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen (EC 1.14.18.*) inhibitor
oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen (EC 1.14.18.*) inhibitors
substance with EC 1.14.18.* (oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen) inhibitor role
An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme using reduced pteridine as one donor and incorporating one atom of oxygen (EC 1.14.16.*).
EC 1.14.16.* (oxidoreductase acting on paired donors, reduced pteridine as one donor, incorporating 1 atom of oxygen) inhibitors
oxidoreductase acting on paired donors, reduced pteridine as one donor, incorporating 1 atom of oxygen (EC 1.14.16.*) inhibitor
oxidoreductase acting on paired donors, reduced pteridine as one donor, incorporating 1 atom of oxygen (EC 1.14.16.*) inhibitors
substance with EC 1.14.16.* (oxidoreductase acting on paired donors, reduced pteridine as one donor, incorporating 1 atom of oxygen) inhibitor role
An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that interferes with the activity of any such enzyme that uses a disulfide as acceptor (EC 1.17.4.*).
EC 1.17.4.* (oxidoreductase acting on CH or CH2 with a disulfide as acceptor) inhibitors
oxidoreductase acting on CH or CH2 with a disulfide as acceptor (EC 1.17.4.*) inhibitor
oxidoreductase acting on CH or CH2 with a disulfide as acceptor (EC 1.17.4.*) inhibitors
substance with EC 1.17.4.* (oxidoreductase acting on CH or CH2 with a disulfide as acceptor) inhibitor role
An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that interferes with the function of any such enzyme that uses oxygen as acceptor (EC 1.17.3.*).
EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitors
oxidoreductase acting on CH or CH2 with oxygen as acceptor (EC 1.17.3.*) inhibitor
oxidoreductase acting on CH or CH2 with oxygen as acceptor (EC 1.17.3.*) inhibitors
substance with EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitor role
An EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.2.1.*).
EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitors
oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor (EC 1.2.1.*) inhibitor
oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor (EC 1.2.1.*) inhibitors
substance with EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor role
An EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.2.3.*).
EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitors
oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor (EC 1.2.3.*) inhibitor
oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor (EC 1.2.3.*) inhibitors
substance with EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor role
An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.3.1.*).
EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor) inhibitor
EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor) inhibitors
EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitor
EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitors
EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitors
oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor (EC 1.3.1.*) inhibitor
oxidoreductase acting on CH-CH group of donor with NAD(+) or NADP(+) as acceptor (EC 1.3.1.*) inhibitors
substance with EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor role
An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the function of any such enzyme in the EC 1.3.98.* (with other, known, acceptors) category.
EC 1.3.98.* (oxidoreductase acting on CH-CH group of donors, with other, known, acceptors) inhibitor
EC 1.3.98.* (oxidoreductase acting on CH-CH group of donors, with other, known, acceptors) inhibitors
EC 1.3.98.* (oxidoreductase acting on donor CH-CH group, with other, known, acceptors) inhibitors
oxidoreductase acting on CH-CH group of donors, with other, known, acceptors (EC 1.3.98.*) inhibitor
oxidoreductase acting on CH-CH group of donors, with other, known, acceptors (EC 1.3.98.*) inhibitors
substance with EC 1.3.98.* (oxidoreductase acting on donor CH-CH group, with other, known, acceptors) inhibitor role
An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the function of any such enzyme in the EC 1.3.98.* (with other acceptors) category.
EC 1.3.99.* (oxidoreductase acting on donor CH-CH group with other acceptors) inhibitors
EC 1.3.99.* (oxidoreductase acting on donor CH-CH group, with other acceptors) inhibitors
oxidoreductase acting on donor CH-CH group with other acceptors (EC 1.3.99.*) inhibitor
oxidoreductase acting on donor CH-CH group with other acceptors (EC 1.3.99.*) inhibitors
substance with EC 1.3.99.* (oxidoreductase acting on donor CH-CH group, with other acceptors) inhibitor role
An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.3.3.*).
EC 1.3.3.* (oxidoreductase acting on donor CH-CH group with oxygen as acceptor) inhibitor
EC 1.3.3.* (oxidoreductase acting on donor CH-CH group with oxygen as acceptor) inhibitors
EC 1.3.3.* (oxidoreductase acting on donor CH-CH group, oxygen as acceptor) inhibitors
oxidoreductase acting on donor CH-CH group with oxygen as acceptor (EC 1.3.3.*) inhibitor
oxidoreductase acting on donor CH-CH group with oxygen as acceptor (EC 1.3.3.*) inhibitors
substance with EC 1.3.3.* (oxidoreductase acting on donor CH-CH group, oxygen as acceptor) inhibitor role
An EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.4.3.*).
EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitors
oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor (EC 1.4.3.*) inhibitor
oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor (EC 1.4.3.*) inhibitors
substance with EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor role
An EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action of any such enzyme using a disulfide as acceptor (EC 1.4.4.*).
EC 1.4.4.* (oxidoreductase acting on donor CH-NH2 group, a disulfide as acceptor) inhibitors
oxidoreductase acting on donor CH-NH2 group, a disulfide as acceptor (EC 1.4.4.*) inhibitor
oxidoreductase acting on donor CH-NH2 group, a disulfide as acceptor (EC 1.4.4.*) inhibitors
substance with EC 1.4.4.* (oxidoreductase acting on donor CH-NH2 group, a disulfide as acceptor) inhibitor role
An EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.5.1.*).
EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitors
oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor (EC 1.5.1.*) inhibitor
oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor (EC 1.5.1.*) inhibitors
substance with EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor role
An EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor that interferes with the action of any such enzyme using a quinone or similar as acceptor (EC 1.6.5.*).
EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitors
oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor (EC 1.6.5.*) inhibitor
oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor (EC 1.6.5.*) inhibitors
substance with EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor role
An EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.6.3.*).
EC 1.6.3.* (oxidoreductase acting on NADH or NADPH with oxygen as acceptor) inhibitors
oxidoreductase acting on NADH or NADPH with oxygen as acceptor (EC 1.6.3.*) inhibitor
oxidoreductase acting on NADH or NADPH with oxygen as acceptor (EC 1.6.3.*) inhibitors
substance with EC 1.6.3.* (oxidoreductase acting on NADH or NADPH with oxygen as acceptor) inhibitor role
An EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.8.1.*).
EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitors
oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor (EC 1.8.1.*) inhibitor
oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor (EC 1.8.1.*) inhibitors
substance with EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitor role
An EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.9.3.*).
EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitors
oxidoreductase acting on donor heme group, oxygen as acceptor (EC 1.9.3.*) inhibitor
oxidoreductase acting on donor heme group, oxygen as acceptor (EC 1.9.3.*) inhibitors
substance with EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor role
An EC 2.1.* (C1-transferase) inhibitor that interferes with the action of any methyltransferase (EC 2.1.1.*).
EC 2.1.1.* (methyltransferase) inhibitor
EC 2.1.1.* (methyltransferase) inhibitors
EC 2.1.1.* (methyltransferases) inhibitors
methyltransferase (EC 2.1.1.*) inhibitor
methyltransferase (EC 2.1.1.*) inhibitors
substance with EC 2.1.1.* (methyltransferases) inhibitor role
An EC 2.1.* (C1-transferase) inhibitor that interferes with the action of any hydroxymethyl-, formyl- and related transferase (EC 2.1.2.*).
EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitors
hydroxymethyl-, formyl- and related transferases (EC 2.1.2.*) inhibitor
hydroxymethyl-, formyl- and related transferases (EC 2.1.2.*) inhibitors
substance with EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor role
An EC 2.2.* (aldehyde or ketone transferase) inhibitor that interferes with the action of any (transketolase or transaldolase (EC 2.2.1.*).
EC 2.2.1.* (transketolase/transaldolase) inhibitors
EC 2.2.1.* (transketolases and transaldolases) inhibitor
EC 2.2.1.* (transketolases and transaldolases) inhibitors
transketolase/transaldolase (EC 2.2.1.*) inhibitor
transketolase/transaldolase (EC 2.2.1.*) inhibitors
substance with EC 2.2.1.* (transketolase/transaldolase) inhibitor role
An EC 2.3.* (acyltransferase) inhibitor that interferes with the action of any aminoacyltransferase (EC 2.3.2.*).
EC 2.3.2.* (aminoacyltransferase) inhibitors
aminoacyltransferase (EC 2.3.2.*) inhibitor
aminoacyltransferase (EC 2.3.2.*) inhibitors
substance with EC 2.3.2.* (aminoacyltransferase) inhibitor role
An EC 2.3.* (acyltransferase) inhibitor that inhibits the action of any acyltransferase transferring groups other than amino-acyl groups (EC 2.3.1.*).
EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitors
acyltransferase transferring other than amino-acyl group EC 2.3.1.* inhibitor
acyltransferase transferring other than amino-acyl group EC 2.3.1.* inhibitors
substance with EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor role
An EC 2.6.* (nitrogenous group transferase) inhibitor that inhibits the action of any transaminase (EC 2.6.1.*).
substance with EC 2.6.1.* (transaminase) inhibitor role
An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any phosphotransferase with an alcohol group as acceptor (EC 2.7.1.*).
EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitors
phosphotransferases with an alcohol group as acceptor (EC 2.7.1.*) inhibitor
phosphotransferases with an alcohol group as acceptor (EC 2.7.1.*) inhibitors
substance with EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor role
An EC 2.4.* (glycosyltransferase) inhibitor that interferes with the activity of any glycosyltransferase in the EC 2.4.99.* (transferring other glycosyl groups) category.
EC 2.4.99.* (glycosyltransferases transferring other glycosyl groups) inhibitors
glycosyltransferases transferring other glycosyl groups (EC 2.4.99.*) inhibitor
glycosyltransferases transferring other glycosyl groups (EC 2.4.99.*) inhibitors
substance with EC 2.4.99.* (glycosyltransferases transferring other glycosyl groups) inhibitor role
An EC 3.11.* (hydrolases acting on C-P bonds) inhibitor that interferes with the activity of any phosphonoacetaldehyde, phosphonoacetate, or phosphonopyruvate hydrolase (EC 3.11.1.*).
EC 3.11.1.* (hydrolases acting on C-P bonds of phosphono-acetaldehyde, -acetate, or -pyruvate) inhibitors
hydrolases acting on C-P bonds of phosphono-acetaldehyde, -acetate, or -pyruvate (EC 3.11.1.*) inhibitor
hydrolases acting on C-P bonds of phosphono-acetaldehyde, -acetate, or -pyruvate (EC 3.11.1.*) inhibitors
substance with EC 3.11.1.* (hydrolases acting on C-P bonds of phosphono-acetaldehyde, -acetate, or -pyruvate) inhibitor role
An EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the action of any aspartic endopeptidase (EC 3.4.23.*).
EC 3.4.23.* (aspartic endopeptidase) inhibitors
EC 3.4.23.* (aspartic endopeptidases) inhibitor
EC 3.4.23.* (aspartic endopeptidases) inhibitors
aspartic endopeptidase (EC 3.4.23.*) inhibitor
aspartic endopeptidase (EC 3.4.23.*) inhibitors
aspartic endopeptidases (EC 3.4.23.*) inhibitor
aspartic endopeptidases (EC 3.4.23.*) inhibitors
substance with EC 3.4.23.* (aspartic endopeptidase) inhibitor role
An EC 3.4.11.* (aminopeptidase) inhibitor that interferes with the action of cytosol alanyl aminopeptidase (EC 3.4.11.14).
EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitors
cytosol alanyl aminopeptidase (EC 3.4.11.14) inhibitor
cytosol alanyl aminopeptidase (EC 3.4.11.14) inhibitors
cytosol alanyl aminopeptidase inhibitors
puromycin-sensitive aminopeptidase inhibitor
puromycin-sensitive aminopeptidase inhibitors
soluble alanyl aminopeptidase inhibitors
thiol-activated aminopeptidase inhibitor
thiol-activated aminopeptidase inhibitors
substance with EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor role
An EC 3.4.14.* (dipeptidyl- and tripeptidyl-peptidases) inhibitor that interferes with the action of dipeptidyl-peptidase II (EC 3.4.14.2).
EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitors
dipeptidyl(amino)peptidase II inhibitors
dipeptidyl-peptidase II (EC 3.4.14.2) inhibitor
dipeptidyl-peptidase II (EC 3.4.14.2) inhibitors
substance with EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor role
An EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme that catalyses transmembrane movement of substances (EC 3.6.3.*).
EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitors
acid anhydride hydrolase catalysing transmembrane movement of substances (EC 3.6.3.*) inhibitor
acid anhydride hydrolase catalysing transmembrane movement of substances (EC 3.6.3.*) inhibitors
substance with EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor role
An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of an unspecified monooxygenase (EC 1.14.14.1).
EC 1.14.14.1 (unspecific monooxygenase) inhibitors
flavoprotein-linked monooxygenase inhibitor
flavoprotein-linked monooxygenase inhibitors
substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidising) inhibitor
substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidising) inhibitors
unspecific monooxygenase (EC 1.14.14.1) inhibitor
unspecific monooxygenase (EC 1.14.14.1) inhibitors
substance with EC 1.14.14.1 (unspecific monooxygenase) inhibitor role
An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the function of any such enzyme using 2-oxoglutarate as one donor and incorporating one atom each of oxygen into both donors (EC 1.14.11.*).
EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitors
EC 1.14.11.* (oxidoreductase acting on paired donors, with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors) inhibitor
EC 1.14.11.* (oxidoreductase acting on paired donors, with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors) inhibitors
oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors (EC 1.14.11.*) inhibitor
oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors (EC 1.14.11.*) inhibitors
oxidoreductase acting on paired donors, with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (EC 1.14.11.*) inhibitor
oxidoreductase acting on paired donors, with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (EC 1.14.11.*) inhibitors
substance with EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor role
An EC 4.1.* (C-C lyase) inhibitor that interferes with the action of any carboxy-lyase (EC 4.1.1.*).
substance with EC 4.1.1.* (carboxy-lyase) inhibitor role
An EC 4.2.* (C-O lyase) inhibitor that interferes with the action of any hydro-lyase (EC 4.2.1.*).
substance with EC 4.2.1.* (hydro-lyases) inhibitor role
A drug which increases the blood glucose level.
An EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitor that interferes with the action of galactose oxidase (EC 1.1.3.9).
D-galactose:oxygen 6-oxidoreductase inhibitor
D-galactose:oxygen 6-oxidoreductase inhibitors
EC 1.1.3.9 (galactose oxidase) inhibitors
substance with EC 1.1.3.9 (galactose oxidase) inhibitor role
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
An EC 3.4.13.* (dipeptidase) inhibitor that interferes with the action of membrane dipeptidase (EC 3.4.13.19).
EC 3.4.13.19 (membrane dipeptidase) inhibitors
glycosyl-phosphatidylinositol-anchored renal dipeptidase inhibitors
membrane dipeptidase (EC 3.4.13.19) inhibitor
membrane dipeptidase (EC 3.4.13.19) inhibitors
substance with EC 3.4.13.19 (membrane dipeptidase) inhibitor role
An enzyme inhibitor that interferes with one or more steps in a metabolic pathway.
An EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme acting on ATP and involved in cellular and subcellular movement (EC 3.6.4.*).
EC 3.6.4.* (hydrolase acting on ATP; involved in cellular and subcellular movement) inhibitor
EC 3.6.4.* (hydrolase acting on ATP; involved in cellular and subcellular movement) inhibitors
EC 3.6.4.* (hydrolases acting on ATP; involved in cellular and subcellular movement) inhibitors
hydrolases acting on ATP; involved in cellular and subcellular movement (EC 3.6.4.*) inhibitor
hydrolases acting on ATP; involved in cellular and subcellular movement (EC 3.6.4.*) inhibitors
substance with EC 3.6.4.* (hydrolases acting on ATP; involved in cellular and subcellular movement) inhibitor role
An EC 3.6.4.* (hydrolases acting on ATP; involved in cellular and subcellular movement) inhibitor that interferes with the action of a non-chaperonin molecular chaperone ATPase (EC 3.6.4.10).
ATP phosphohydrolase (polypeptide-polymerising) inhibitor
ATP phosphohydrolase (polypeptide-polymerising) inhibitors
ATP phosphohydrolase (polypeptide-polymerizing) inhibitor
ATP phosphohydrolase (polypeptide-polymerizing) inhibitors
EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitors
molecular chaperone Hsc70 ATPase inhibitor
molecular chaperone Hsc70 ATPase inhibitors
non-chaperonin molecular chaperone ATPase (EC 3.6.4.10) inhibitor
non-chaperonin molecular chaperone ATPase (EC 3.6.4.10) inhibitors
substance with EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitor role
An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of trypsin (EC 3.4.21.4).
substance with EC 3.4.21.4 (trypsin) inhibitor role
Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds.
Any fungal metabolite produced during a metabolic reaction in the mould, Aspergillus.
substance with Aspergillus metabolite role
Any fungal metabolite produced during a metabolic reaction in the mould, Chaetomium.
substance with Chaetomium metabolite role
Any fungal metabolite produced during a metabolic reaction in Penicillium.
substance with Penicillium metabolite role
Any human metabolite produced by metabolism of a xenobiotic compound in humans.
substance with human xenobiotic metabolite role
Any fungal metabolite produced by metabolism of a xenobiotic compound in fungi.
substance with fungal xenobiotic metabolite role
Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
substance with bacterial metabolite role
Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
substance with Escherichia coli metabolite role
Any bacterial metabolite produced during a metabolic reaction in Streptococcus pneumoniae.
Streptococcus pneumoniae secondary metabolites
substance with Streptococcus pneumoniae metabolite role
Any bacterial metabolite produced by metabolism of a xenobiotic compound in bacteria.
substance with bacterial xenobiotic metabolite role
A hormone antagonist that blocks corticotropin-releasing factor receptors
corticotropin-releasing factor receptor antagonists
substance with corticotropin-releasing factor receptor antagonist role
A synthetic or semi-synthetic compound that has oestrogenic activity.
Any compound produced by a plant that happens to have estrogenic activity.
Any compound produced by a fungus that happens to have estrogenic activity.
An antagonist that binds to and activates aryl hydrocarbon receptors (AhRs).
substance with aryl hydrocarbon receptor antagonist role
An EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor that interferes with the action of any such enzyme in the EC 1.10.99.* category.
EC 1.10.99.* (oxidoreductases acting on diphenols and related substances as donors, other acceptors) inhibitors
oxidoreductases acting on diphenols and related substances as donors, other acceptors (EC 1.10.99.*) inhibitor
oxidoreductases acting on diphenols and related substances as donors, other acceptors (EC 1.10.99.*) inhibitors
substance with EC 1.10.99.* (oxidoreductases acting on diphenols and related substances as donors, other acceptors) inhibitor role
An EC 1.10.99.* (oxidoreductases acting on diphenols and related substances as donors, other acceptors) inhibitor that interferes with the action of ribosyldihydronicotinamide dehydrogenase (quinone), EC 1.10.99.2.
1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide:quinone oxidoreductase inhibitor
1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide:quinone oxidoreductase inhibitors
EC 1.10.99.2 (ribosyldihydronicotinamide dehydrogenase (quinone)) inhibitor
EC 1.10.99.2 (ribosyldihydronicotinamide dehydrogenase (quinone)) inhibitors
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitors
N-ribosyldihydronicotinamide dehydrogenase (quinone) inhibitor
N-ribosyldihydronicotinamide dehydrogenase (quinone) inhibitors
NAD(P)H:quinone oxidoreductase-2 inhibitor
NAD(P)H:quinone oxidoreductase-2 inhibitors
NAD(P)H:quinone oxidoreductase2 inhibitor
NAD(P)H:quinone oxidoreductase2 inhibitors
ribosyldihydronicotinamide dehydrogenase (quinone) (EC 1.10.99.2) inhibitor
ribosyldihydronicotinamide dehydrogenase (quinone) (EC 1.10.99.2) inhibitors
substance with EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor role
An EC 2.3.* (acyltransferase) inhibitor that interferes with the action of an acyltransferase which converts the acyl group to an alkyl group on transfer (EC 2.3.3.*).
EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitors
acyltransferase converting acyl to alkyl group on transfer (EC 2.3.3.*) inhibitor
acyltransferase converting acyl to alkyl group on transfer (EC 2.3.3.*) inhibitors
substance with EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor role
An EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor that interferes with the action of citrate (Si)-synthase, EC 2.3.3.1.
EC 2.3.3.1 (citrate (Si)-synthase) inhibitor
EC 2.3.3.1 (citrate (Si)-synthase) inhibitors
EC 2.3.3.1 [citrate (Si)-synthase] inhibitors
acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming] inhibitor
acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming] inhibitors
citrate (Si)-synthase (EC 2.3.3.1) inhibitor
citrate (Si)-synthase (EC 2.3.3.1) inhibitors
citrate oxaloacetate-lyase [(pro-3S)-CH2COO->acetyl-CoA] inhibitor
citrate oxaloacetate-lyase [(pro-3S)-CH2COO->acetyl-CoA] inhibitors
citrate oxaloacetate-lyase, CoA-acetylating inhibitor
citrate oxaloacetate-lyase, CoA-acetylating inhibitors
substance with EC 2.3.3.1 [citrate (Si)-synthase] inhibitor role
An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of 4-nitrophenylphosphatase (EC 3.1.3.41).
4-nitrophenylphosphatase (EC 3.1.3.41) inhibitor
4-nitrophenylphosphatase (EC 3.1.3.41) inhibitors
4-nitrophenylphosphate phosphohydrolase inhibitor
4-nitrophenylphosphate phosphohydrolase inhibitors
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitors
Ecto-p-nitrophenyl phosphatase inhibitor
Ecto-p-nitrophenyl phosphatase inhibitors
p-nitrophenylphosphate phosphohydrolase inhibitor
p-nitrophenylphosphate phosphohydrolase inhibitors
substance with EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor role
A compound that alters the structure of mucus so as to decrease its viscosity and thereby facilitate its removal by ciliary action and expectoration. Compare with antitussives, which suppress the cough reflex, and expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing.
Compounds that are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing. Compare with mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration, and antitussives, which suppress the cough reflex.
An EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action of any such enzyme using a iron-sulfur protein as acceptor (EC 1.4.7.*).
EC 1.4.7.* (oxidoreductase acting on donor CH-NH2 group, Fe-S protein as acceptor) inhibitors
inhibitor of oxidoreductase acting on donor CH-NH2 group, Fe-S protein as acceptor
inhibitors of oxidoreductase acting on donor CH-NH2 group, Fe-S protein as acceptor
oxidoreductase acting on donor CH-NH2 group, Fe-S protein as acceptor (EC 1.4.7.*) inhibitor
oxidoreductase acting on donor CH-NH2 group, Fe-S protein as acceptor (EC 1.4.7.*) inhibitors
substance with EC 1.4.7.* (oxidoreductase acting on donor CH-NH2 group, Fe-S protein as acceptor) inhibitor role
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49).
EC 2.5.1.49 (O-acetylhomoserine aminocarboxypropyltransferase) inhibitors
O-acetyl-L-homoserine acetate-lyase (adding methanethiol) inhibitor
O-acetyl-L-homoserine acetate-lyase (adding methanethiol) inhibitors
O-acetyl-L-homoserine sulfhydrolase inhibitor
O-acetyl-L-homoserine sulfhydrolase inhibitors
O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase inhibitor
O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase inhibitors
O-acetylhomoserine (thiol)-lyase inhibitor
O-acetylhomoserine (thiol)-lyase inhibitors
O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49) inhibitor
O-acetylhomoserine aminocarboxypropyltransferase (EC 2.5.1.49) inhibitors
O-acetylhomoserine aminocarboxypropyltransferase inhibitor
O-acetylhomoserine aminocarboxypropyltransferase inhibitors
O-acetylhomoserine sulfhydrolase inhibitor
O-acetylhomoserine sulfhydrolase inhibitors
substance with EC 2.5.1.49 (O-acetylhomoserine aminocarboxypropyltransferase) inhibitor role
An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of serine-sulfate ammonia-lyase (EC 4.3.1.10).
EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitors
L-serine-O-sulfate ammonia-lyase (pyruvate-forming) inhibitor
L-serine-O-sulfate ammonia-lyase (pyruvate-forming) inhibitors
serine-sulfate ammonia-lyase (EC 4.3.1.10) inhibitor
serine-sulfate ammonia-lyase (EC 4.3.1.10) inhibitors
substance with EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor role
An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using a quinone or related compound as acceptor (EC 1.3.5.*).
EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitors
inhibitor of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor
inhibitor of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*)
inhibitors of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor
inhibitors of oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*)
oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*) inhibitor
oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor (EC 1.3.5.*) inhibitors
substance with EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor role
An EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor that interferes with the action of dihydroorotate dehydrogenase (quinone), EC 1.3.5.2.
(S)-dihydroorotate:(acceptor) oxidoreductase inhibitor
(S)-dihydroorotate:(acceptor) oxidoreductase inhibitors
(S)-dihydroorotate:acceptor oxidoreductase inhibitor
(S)-dihydroorotate:acceptor oxidoreductase inhibitors
(S)-dihydroorotate:quinone oxidoreductase inhibitor
(S)-dihydroorotate:quinone oxidoreductase inhibitors
EC 1.3.5.2 (dihydroorotate dehydrogenase (quinone)) inhibitor
EC 1.3.5.2 (dihydroorotate dehydrogenase (quinone)) inhibitors
EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitors
dihydroorotate:ubiquinone oxidoreductase inhibitor
dihydroorotate:ubiquinone oxidoreductase inhibitors
substance with EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitor role
An EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor that interferes with the action of any such enzyme using a cytochrome as acceptor (EC 1.10.2.*).
EC 1.10.2.* (oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor) inhibitors
inhibitor of an oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor (EC 1.10.2.*)
inhibitors of an oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor (EC 1.10.2.*)
oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor (EC 1.10.2.*) inhibitor
oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor (EC 1.10.2.*) inhibitors
substance with EC 1.10.2.* (oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor) inhibitor role
An EC 1.10.2.* (oxidoreductase acting on diphenols and related substances as donors with a cytochrome as acceptor) inhibitor that interferes with the action of quinol--cytochrome-c reductase (EC 1.10.2.2).
EC 1.10.2.2 (quinol--cytochrome-c reductase) inhibitors
inhibitor of quinol--cytochrome-c reductase (EC 1.10.2.2)
inhibitors of quinol--cytochrome-c reductase (EC 1.10.2.2)
quinol--cytochrome-c reductase (EC 1.10.2.2) inhibitor
quinol--cytochrome-c reductase (EC 1.10.2.2) inhibitors
substance with EC 1.10.2.2 (quinol--cytochrome-c reductase) inhibitor role
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of 15-hydroxyprostaglandin dehydrogenase (NAD(+)) (EC 1.1.1.141).
(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD(+) 15-oxidoreductase inhibitor
(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD(+) 15-oxidoreductase inhibitors
(5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate:NAD(+) 15-oxidoreductase inhibitor
(5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate:NAD(+) 15-oxidoreductase inhibitors
11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD(+) 15-oxidoreductase inhibitor
11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD(+) 15-oxidoreductase inhibitors
15-hydroxyprostaglandin dehydrogenase (NAD(+)) (EC 1.1.1.141) inhibitor
15-hydroxyprostaglandin dehydrogenase (NAD(+)) (EC 1.1.1.141) inhibitors
15-hydroxyprostaglandin dehydrogenase (NAD(+)) inhibitor
15-hydroxyprostaglandin dehydrogenase (NAD(+)) inhibitors
15-hydroxyprostaglandin dehydrogenase inhibitor
15-hydroxyprostaglandin dehydrogenase inhibitors
15-hydroxyprostanoic dehydrogenase inhibitor
15-hydroxyprostanoic dehydrogenase inhibitors
EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitors
NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase (type I) inhibitor
NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase (type I) inhibitors
NAD-specific 15-hydroxyprostaglandin dehydrogenase inhibitor
NAD-specific 15-hydroxyprostaglandin dehydrogenase inhibitors
substance with EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor role
An EC 1.21.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.21.3.*).
EC 1.21.3.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor) inhibitors
inhibitor of oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor
inhibitor of oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor (EC 1.21.3.*)
inhibitors of oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor
inhibitors of oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor (EC 1.21.3.*)
oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor (EC 1.21.3.*) inhibitor
oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor (EC 1.21.3.*) inhibitors
substance with EC 1.21.3.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor) inhibitor role
An EC 1.21.3.* (oxidoreductase acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor) inhibitor that interferes with the action of reticuline oxidase (EC 1.21.3.3, previously EC 1.5.3.9).
(S)-reticuline:oxygen oxidoreductase (methylene-bridge-forming) inhibitor
(S)-reticuline:oxygen oxidoreductase (methylene-bridge-forming) inhibitors
EC 1.21.3.3 (reticuline oxidase) inhibitors
berberine-bridge-forming enzyme inhibitor
berberine-bridge-forming enzyme inhibitors
reticuline oxidase (EC 1.21.3.3) inhibitor
reticuline oxidase (EC 1.21.3.3) inhibitors
tetrahydroprotoberberine synthase inhibitor
tetrahydroprotoberberine synthase inhibitors
substance with EC 1.21.3.3 (reticuline oxidase) inhibitor role
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase (EC 2.1.1.116).
3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase (EC 2.1.1.116) inhibitor
3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase (EC 2.1.1.116) inhibitors
EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitors
S-adenosyl-L-methionine:3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase inhibitor
S-adenosyl-L-methionine:3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase inhibitors
substance with EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor role
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of IkappaB kinase (EC 2.7.11.10).
ATP:[IkappaB protein] phosphotransferase
ATP:[IkappaB protein] phosphotransferase inhibitor
EC 2.7.11.10 (IkappaB kinase) inhibitors
IkappaB kinase (EC 2.7.11.10) inhibitors
substance with EC 2.7.11.10 (IkappaB kinase) inhibitor role
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of (S)-tetrahydroprotoberberine N-methyltransferase (EC 2.1.1.122).
(S)-tetrahydroprotoberberine N-methyltransferase (EC 2.1.1.122) inhibitor
(S)-tetrahydroprotoberberine N-methyltransferase (EC 2.1.1.122) inhibitors
(S)-tetrahydroprotoberberine N-methyltransferase inhibitor
(S)-tetrahydroprotoberberine N-methyltransferase inhibitors
EC 2.1.1.122 ((S)-tetrahydroprotoberberine N-methyltransferase) inhibitor
EC 2.1.1.122 ((S)-tetrahydroprotoberberine N-methyltransferase) inhibitors
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitors
S-adenosyl-L-methionine:(S)-7,8,13,14-tetrahydroprotoberberine cis-N-methyltransferase inhibitor
S-adenosyl-L-methionine:(S)-7,8,13,14-tetrahydroprotoberberine cis-N-methyltransferase inhibitors
tetrahydroprotoberberine cis-N-methyltransferase inhibitor
tetrahydroprotoberberine cis-N-methyltransferase inhibitors
substance with EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor role
An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any such enzyme acting on the C-N bond of nitriles (EC 3.5.5.*).
EC 3.5.5.* (hydrolase acting on C-N bonds in nitriles) inhibitors
hydrolase acting on C-N bonds in nitriles (EC 3.5.5.*) inhibitor
hydrolase acting on C-N bonds in nitriles (EC 3.5.5.*) inhibitors
inhibitor of hydrolases acting on C-N bonds in nitriles
inhibitors of hydrolases acting on C-N bonds in nitriles
substance with EC 3.5.5.* (hydrolase acting on C-N bonds in nitriles) inhibitor role
An EC 3.5.5.* (hydrolase acting on C-N bonds in nitriles) inhibitor that interferes with the action of nitrilase (EC 3.5.5.1).
substance with EC 3.5.5.1 (nitrilase) inhibitor role
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of prostaglandin-E2 9-reductase (EC 1.1.1.189).
(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP(+) 9-oxidoreductase inhibitor
(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP(+) 9-oxidoreductase inhibitors
9-keto-prostaglandin E2 reductase inhibitor
9-keto-prostaglandin E2 reductase inhibitors
9-ketoprostaglandin reductase inhibitors
EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitors
prostaglandin E 9-ketoreductase inhibitor
prostaglandin E 9-ketoreductase inhibitors
prostaglandin E2-9-oxoreductase inhibitor
prostaglandin E2-9-oxoreductase inhibitors
prostaglandin-E2 9-reductase (EC 1.1.1.189) inhibitor
prostaglandin-E2 9-reductase (EC 1.1.1.189) inhibitors
reductase, 15-hydroxy-9-oxoprostaglandin inhibitor
reductase, 15-hydroxy-9-oxoprostaglandin inhibitors
substance with EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor role
An agonist that selectively binds to and activates the Toll-like receptor 2 (TLR 2, TLR-2) protein.
substance with Toll-like receptor 2 agonist role
A dye used in microscopic or electron microscopic examination of cells and tissues to give contrast and to highlight particular features of interest, such as nuclei and cytoplasm.
A food additive that imparts colour to food. In European countries, E-numbers for permitted food colours are from E 100 to E 199, divided into yellows (E 100-109), oranges (E 110-119), reds (E 120-129), blues and violets (E 130-139), greens (E 140-149), browns and blacks (E 150-159), and others (E 160-199).
An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of pantothenate kinase (EC 2.7.1.33).
ATP:(R)-pantothenate 4'-phosphotransferase inhibitor
ATP:(R)-pantothenate 4'-phosphotransferase inhibitors
ATP:pantothenate 4'-phosphotransferase inhibitor
ATP:pantothenate 4'-phosphotransferase inhibitors
EC 2.7.1.33 (pantothenate kinase) inhibitors
pantothenate kinase (EC 2.7.1.33) inhibitor
pantothenate kinase (EC 2.7.1.33) inhibitors
pantothenate kinase (phosphorylating) inhibitor
pantothenate kinase (phosphorylating) inhibitors
substance with EC 2.7.1.33 (pantothenate kinase) inhibitor role
An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of anthrax lethal factor endopeptidase (EC 3.4.24.83).
EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitors
anthrax lethal factor endopeptidase (EC 3.4.24.83) inhibitor
anthrax lethal factor endopeptidase (EC 3.4.24.83) inhibitors
substance with EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor role
Any protective agent that is able to prevent damage to the heart.
substance with cardioprotective agent role
An agonist that selectively binds to and activates a pregnane X receptor.
substance with pregnane X receptor agonist role
Any compound that activates UDP-glucuronosyltransferase (EC 2.4.1.17).
substance with UDP-glucuronosyltransferase activator role
An agonist that selectively binds to and activates androstane receptors.
constitutive androstane receptor agonist
constitutive androstane receptor agonists
substance with androstane receptor agonist role
An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of trypanothione-disulfide reductase (EC 1.8.1.12).
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitors
N(1),N(8)-bis(glutathionyl)spermidine reductase inhibitor
N(1),N(8)-bis(glutathionyl)spermidine reductase inhibitors
NADPH2:trypanothione oxidoreductase inhibitor
NADPH2:trypanothione oxidoreductase inhibitors
NADPH:trypanothione oxidoreductase inhibitor
NADPH:trypanothione oxidoreductase inhibitors
trypanothione-disulfide reductase (EC 1.8.1.12) inhibitor
trypanothione-disulfide reductase (EC 1.8.1.12) inhibitors
trypanothione:NADP(+) oxidoreductase inhibitor
trypanothione:NADP(+) oxidoreductase inhibitors
substance with EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor role
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of prostaglandin-F synthase (EC 1.1.1.188).
(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP(+) 11-oxidoreductase inhibitor
(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP(+) 11-oxidoreductase inhibitors
EC 1.1.1.188 (prostaglandin-F synthase) inhibitors
NADPH-dependent prostaglandin D2 11-keto reductase inhibitor
NADPH-dependent prostaglandin D2 11-keto reductase inhibitors
prostaglandin 11-keto reductase inhibitor
prostaglandin 11-keto reductase inhibitors
prostaglandin 11-ketoreductase inhibitor
prostaglandin 11-ketoreductase inhibitors
prostaglandin D2-ketoreductase inhibitor
prostaglandin D2-ketoreductase inhibitors
prostaglandin-D2 11-reductase inhibitors
reductase, 15-hydroxy-11-oxoprostaglandin inhibitor
reductase, 15-hydroxy-11-oxoprostaglandin inhibitors
synthetase, prostaglandin F2alpha inhibitor
synthetase, prostaglandin F2alpha inhibitors
substance with EC 1.1.1.188 (prostaglandin-F synthase) inhibitor role
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of shikimate dehydrogenase (EC 1.1.1.25).
EC 1.1.1.25 (shikimate dehydrogenase) inhibitors
shikimate dehydrogenase (EC 1.1.1.25) inhibitor
shikimate dehydrogenase (EC 1.1.1.25) inhibitors
shikimate:NADP(+) 3-oxidoreductase inhibitor
shikimate:NADP(+) 3-oxidoreductase inhibitors
shikimate:NADP(+) 5-oxidoreductase inhibitor
shikimate:NADP(+) 5-oxidoreductase inhibitors
shikimate:NADP(+) oxidoreductase inhibitor
shikimate:NADP(+) oxidoreductase inhibitors
substance with EC 1.1.1.25 (shikimate dehydrogenase) inhibitor role
An agonist that binds to and activates bradykinin receptors
substance with bradykinin receptor agonist role
A bradykinin agonist that binds to and activates bradykinin B2 receptors.
substance with bradykinin receptor B2 agonist role
Any product obtained as a result of thermally induced non-enzymatic degradation.
substance with thermal degradation product role
Any thermal degradation product obtained as a result of a chemical reaction between an amino acid and a reducing sugar (Maillard reaction, a non-enzymatic browning procedure that usually imparts flavour to starch-based food products).
substance with Maillard reaction product role
A phsychotropic drug that improves wakefulness and alertness, and reduces tiredness, drowsiness, and the need for sleep. Eugeroics are relatively non-addictive and are used in the treatment of narcolepsy and other sleep disorders.
A diuretic that acts on the ascending loop of Henle in the kidney.
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of 1-deoxy-D-xylulose-5-phosphate reductoisomerase (EC 1.1.1.267).
1-deoxy-D-xylulose-5-phosphate isomeroreductase inhibitor
1-deoxy-D-xylulose-5-phosphate isomeroreductase inhibitors
1-deoxy-D-xylulose-5-phosphate reductoisomerase (EC 1.1.1.267) inhibitor
1-deoxy-D-xylulose-5-phosphate reductoisomerase (EC 1.1.1.267) inhibitors
1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitor
1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors
1-deoxyxylulose-5-phosphate reductoisomerase inhibitor
1-deoxyxylulose-5-phosphate reductoisomerase inhibitors
2-C-methyl-D-erythritol-4-phosphate:NADP(+) oxidoreductase (isomerising) inhibitor
2-C-methyl-D-erythritol-4-phosphate:NADP(+) oxidoreductase (isomerising) inhibitors
2-C-methyl-D-erythritol-4-phosphate:NADP(+) oxidoreductase (isomerizing) inhibitor
2-C-methyl-D-erythritol-4-phosphate:NADP(+) oxidoreductase (isomerizing) inhibitors
2C-methyl-D-erythritol-4-phosphate (MEP) synthase inhibitor
2C-methyl-D-erythritol-4-phosphate (MEP) synthase inhibitors
EC 1.1.1.267 (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibitors
substance with EC 1.1.1.267 (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibitor role
An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of histidine ammonia-lyase (EC 4.3.1.3).
EC 4.3.1.3 (histidine ammonia-lyase) inhibitors
L-histidine ammonia-lyase (urocanate-forming) inhibitor
L-histidine ammonia-lyase (urocanate-forming) inhibitors
histidine ammonia-lyase (EC 4.3.1.3) inhibitor
histidine ammonia-lyase (EC 4.3.1.3) inhibitors
substance with EC 4.3.1.3 (histidine ammonia-lyase) inhibitor role
Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the action of any omega-peptidase (EC 3.4.19.*).
EC 3.4.19.* (omega-peptidase) inhibitors
omega-peptidase (EC 3.4.19.*) inhibitors
substance with EC 3.4.19.* (omega-peptidase) inhibitor role
An EC 3.4.19.* (omega-peptidase) inhibitor that interferes with the action of pyroglutamyl-peptidase I (EC 3.4.19.3).
EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitors
L-pyroglutamyl peptide hydrolase inhibitor
L-pyroglutamyl peptide hydrolase inhibitors
L-pyrrolidonecarboxylate peptidase inhibitor
L-pyrrolidonecarboxylate peptidase inhibitors
pyroglutamyl-peptidase I (EC 3.4.19.3) inhibitor
pyroglutamyl-peptidase I (EC 3.4.19.3) inhibitors
pyrrolidone-carboxyl peptidase inhibitor
pyrrolidone-carboxyl peptidase inhibitors
pyrrolidonecarboxylyl peptidase inhibitor
pyrrolidonecarboxylyl peptidase inhibitors
pyrrolidonyl peptidase inhibitors5-oxoprolyl-peptidase inhibitor
substance with EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor role
A drug used to relieve nasal congestion in the upper respiratory tract.
An EC 3.4.24.* (metalloendopeptidase) inhibitor that inhibits the action of meprin A (EC 3.4.24.18).
N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase inhibitor
N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase inhibitors
substance with EC 3.4.24.18 (meprin A) inhibitor role
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of phospholipid-translocating ATPase (EC 3.6.3.1).
ATP phosphohydrolase (phospholipid-flipping) inhibitor
ATP phosphohydrolase (phospholipid-flipping) inhibitors
EC 3.6.3.1 (phospholipid-translocating ATPase) inhibitors
aminophospholipid-transporting ATPase inhibitor
aminophospholipid-transporting ATPase inhibitors
phospholipid-translocating ATPase (EC 3.6.3.1) inhibitor
phospholipid-translocating ATPase (EC 3.6.3.1) inhibitors
phospholipid-translocating ATPase inhibitor
phospholipid-translocating ATPase inhibitors
phospholipid-transporting ATPase inhibitor
phospholipid-transporting ATPase inhibitors
substance with EC 3.6.3.1 (phospholipid-translocating ATPase) inhibitor role
An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of xenobiotic-transporting ATPase (EC 3.6.3.44).
ATP phosphohydrolase (steroid-exporting) inhibitor
ATP phosphohydrolase (steroid-exporting) inhibitors
ATP phosphohydrolase (xenobiotic-exporting) inhibitor
ATP phosphohydrolase (xenobiotic-exporting) inhibitors
EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitors
pleiotropic-drug-resistance protein inhibitor
pleiotropic-drug-resistance protein inhibitors
xenobiotic-transporting ATPase (EC 3.6.3.44) inhibitor
xenobiotic-transporting ATPase (EC 3.6.3.44) inhibitors
xenobiotic-transporting ATPase inhibitor
xenobiotic-transporting ATPase inhibitors
substance with EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor role
Any inhibitor of the trasporter protein ATP/ADP translocase.
substance with ATP/ADP translocase inhibitor role
An EC 3.1.4.* (phosphoric diester hydrolase) inhibitor that interferes with the action of a 3',5'-cyclic-AMP phosphodiesterase (EC 3.1.4.53).
3',5'-cyclic-AMP 5'-nucleotidohydrolase inhibitor
3',5'-cyclic-AMP 5'-nucleotidohydrolase inhibitors
3',5'-cyclic-AMP phosphodiesterase (EC 3.1.4.53) inhibitor
3',5'-cyclic-AMP phosphodiesterase (EC 3.1.4.53) inhibitors
3',5'-cyclic-AMP phosphodiesterase inhibitor
3',5'-cyclic-AMP phosphodiesterase inhibitors
EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitors
cAMP-specific phosphodiesterase inhibitor
cAMP-specific phosphodiesterase inhibitors
substance with EC 3.1.4.53 (3',5'-cyclic-AMP phosphodiesterase) inhibitor role
An EC 1.2.1.* (oxidoreductase acting on donor aldehyde/oxo group with NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88).
1-pyrroline-5-carboxylate dehydrogenase inhibitor
1-pyrroline-5-carboxylate dehydrogenase inhibitors
1-pyrroline-5-carboxylate:NAD(+) oxidoreductase inhibitor
1-pyrroline-5-carboxylate:NAD(+) oxidoreductase inhibitors
Delta(1)-pyrroline-5-carboxylate dehydrogenase inhibitor
Delta(1)-pyrroline-5-carboxylate dehydrogenase inhibitors
Delta(1)-pyrroline-5-carboxylic acid dehydrogenase inhibitor
Delta(1)-pyrroline-5-carboxylic acid dehydrogenase inhibitors
EC 1.2.1.88 (L-glutamate gamma-semialdehyde dehydrogenase) inhibitors
L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88) inhibitor
L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88) inhibitors
L-glutamate gamma-semialdehyde dehydrogenase inhibitor
L-glutamate gamma-semialdehyde dehydrogenase inhibitors
L-glutamate gamma-semialdehyde:NAD(+) oxidoreductase inhibitor
L-glutamate gamma-semialdehyde:NAD(+) oxidoreductase inhibitors
L-pyrroline-5-carboxylate-NAD(+) oxidoreductase inhibitor
L-pyrroline-5-carboxylate-NAD(+) oxidoreductase inhibitors
pyrroline-5-carboxylate dehydrogenase inhibitor
pyrroline-5-carboxylate dehydrogenase inhibitors
pyrroline-5-carboxylic acid dehydrogenase inhibitor
pyrroline-5-carboxylic acid dehydrogenase inhibitors
substance with EC 1.2.1.88 (L-glutamate gamma-semialdehyde dehydrogenase) inhibitor role
An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of 13-deoxydaunorubicin hydroxylase (EC 1.14.13.181).
13-deoxydaunorubicin hydroxylase (EC 1.14.13.181) inhibitor
13-deoxydaunorubicin hydroxylase (EC 1.14.13.181) inhibitors
13-deoxydaunorubicin hydroxylase inhibitor
13-deoxydaunorubicin hydroxylase inhibitors
13-deoxydaunorubicin,NADPH:oxygen oxidoreductase (13-hydroxylating) inhibitor
13-deoxydaunorubicin,NADPH:oxygen oxidoreductase (13-hydroxylating) inhibitors
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitors
substance with EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor role
An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of quinine 3-monooxygenase (EC 1.14.13.67).
EC 1.14.13.67 (quinine 3-monooxygenase) inhibitors
quinine 3-monooxygenase (EC 1.14.13.67) inhibitor
quinine 3-monooxygenase (EC 1.14.13.67) inhibitors
quinine,NADPH:oxygen oxidoreductase inhibitor
quinine,NADPH:oxygen oxidoreductase inhibitors
substance with EC 1.14.13.67 (quinine 3-monooxygenase) inhibitor role
Any environmental contaminant that is resistant to environmental degradation through photolytic, biological or chemical processes. Such substances can have significant impact on health and the environment, as they persist in the environment, bioaccumulate in animal tissue and so biomagnify in food chains.
substance with persistent organic pollutant role
An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of diaminopropionate ammonia-lyase (EC 4.3.1.15).
2,3-diaminopropanoate ammonia-lyase (adding H2O; pyruvate-forming) inhibitor
2,3-diaminopropanoate ammonia-lyase (adding H2O; pyruvate-forming) inhibitors
2,3-diaminopropanoate ammonia-lyase (adding water; pyruvate-forming) inhibitor
2,3-diaminopropanoate ammonia-lyase (adding water; pyruvate-forming) inhibitors
2,3-diaminopropanoate ammonia-lyase inhibitor
2,3-diaminopropanoate ammonia-lyase inhibitors
2,3-diaminopropionate ammonia-lyase inhibitor
2,3-diaminopropionate ammonia-lyase inhibitors
EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitors
alpha,beta-diaminopropionate ammonia-lyase inhibitor
alpha,beta-diaminopropionate ammonia-lyase inhibitors
diaminopropionate ammonia-lyase (EC 4.3.1.15) inhibitor
diaminopropionate ammonia-lyase (EC 4.3.1.15) inhibitors
diaminopropionate ammonia-lyase inhibitor
diaminopropionate ammonia-lyase inhibitors
substance with EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor role
An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of EC 1.14.13.70 (sterol 14alpha-demethylase).
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitors
sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving) inhibitor
sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving) inhibitors
substance with EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor role
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4).
substance with EC 3.5.1.4 (amidase) inhibitor role
An EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor that inhibits the action of leucine--tRNA synthetase (EC 6.1.1.4).
EC 6.1.1.4 (leucine--tRNA ligase) inhibitors
L-leucine:tRNA(Leu) ligase (AMP-forming) inhibitor
L-leucine:tRNA(Leu) ligase (AMP-forming) inhibitors
leucyl-transfer RNA synthetase inhibitor
leucyl-transfer RNA synthetase inhibitors
leucyl-transfer ribonucleate synthetase inhibitor
leucyl-transfer ribonucleate synthetase inhibitors
leucyl-transfer ribonucleic acid synthetase inhibitor
leucyl-transfer ribonucleic acid synthetase inhibitors
substance with EC 6.1.1.4 (leucine--tRNA ligase) inhibitor role
A food additive that is used to make or keep fruit or vegetable tissues firm and crisp. or which interacts with gelling agents such as pectin to produce or strengthen a gel.
An antioxidant that used as a food additives to help guard against food deterioration.
A food preservative that acts by chelating with metal cations (particularly those of copper, iron and nickel) that catalyse the oxidation of fats in food.
A substance added to powdered or granulated materials in order to prevent the formation of lumps and so facilitate its packaging or transport.
An anticaking agent that is used to reduced the tendency of particles of food to adhere to one another.
substance with food anticaking agent role
A food additive that is used to preserve the structure of food.
A compound that is used to keep a substance moist.
A humectant that is used as a food additive to prevent foodstuffs from drying out.
A food additive that is used to increase the viscosity of foodstuffs.
substance with food thickening agent role
A food additive which liberates gas so as to increase the volume of a dough or batter, resulting in a lighter and softer finished product.
A food additive that is applied to the external surface or a food in order to give a smooth shiny appearance and/or to provide a protective coating to foodstuffs.
A substance that reduces and hinders the formation of foam in solutions and other liquids during their industrial or laboratory processing.
A food additive that is a (generally inert) gas which is used to envelop foodstuffs during packing and so protect them from unwanted chemical reactions such as food spoilage or oxidation during subsequent transport and storage. The term includes propellant gases, used to expel foods from a container.
A food additive that is used for the purpose of decolourising food.
substance with food bleaching agent role
A food additive that contributes to the bulk of a food without significantly contributing to its available energy value.
A food additive that intensifies, retains or stabilises the colour of a food.
substance with food colour retention agent role
A food additive that makes it possible to form or maintain a uniform dispersion of a gaseous phase in a liquid or solid phase.
Any inhibitor of Wiskott-Aldrich syndrome protein.
Wiskott-Aldrich syndrome protein inhibitors
substance with Wiskott-Aldrich syndrome protein inhibitor role
A food additive that enhances the texture of a foodstuff by gel formation.
A propellant that is used to expel foods from an aerosol container.
An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of adenosylmethionine decarboxylase (EC 4.1.1.50).
EC 4.1.1.50 (adenosylmethionine decarboxylase) inhibitors
S-adenosyl-L-methionine carboxy-lyase [(5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium-salt-forming] inhibitor
S-adenosyl-L-methionine carboxy-lyase [(5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium-salt-forming] inhibitors
S-adenosyl-L-methionine carboxy-lyase [S-adenosyl 3-(methylthio)propylamine-forming] inhibitor
S-adenosyl-L-methionine carboxy-lyase [S-adenosyl 3-(methylthio)propylamine-forming] inhibitors
S-adenosyl-L-methionine carboxy-lyase inhibitor
S-adenosyl-L-methionine carboxy-lyase inhibitors
S-adenosyl-L-methionine decarboxylase inhibitor
S-adenosyl-L-methionine decarboxylase inhibitors
S-adenosylmethionine decarboxylase inhibitor
S-adenosylmethionine decarboxylase inhibitors
substance with EC 4.1.1.50 (adenosylmethionine decarboxylase) inhibitor role
A substance that inhibits any of the Wnt signalling pathway, a group of signal transduction pathways made of proteins that pass signals from outside of a cell through cell surface receptors to the inside of the cell.
substance with Wnt signalling inhibitor role
A food additive that is used to reduce or prevent foaming during the processing or manufacture of foodstuffs.
substance with food antifoaming agent role
A food additive that is used to dilute, disperse or dissolve a food additive or nutrient without altering its function. Carriers are used to facilitate the handling or use of the food additive or nutrient.
substance with food additive carrier role
Any small molecule that mimics the action of an enzyme.
An antagonist which acts by inhibiting the action of vitamin B1
substance with vitamin B1 antagonist role
A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants.
Any minor or unwanted substance introduced into the environment that can have undesired effects.
substance with environmental contaminant role
Any unwanted chemical in food. The term includes agrochemicals and industrial chemicals that may contaminate foodstuffs during their production, transportation or storage.
substance with environmental food contaminant role
Any metabolite that is produced during a metabolite reaction in lichens (composite organisms consisting of a fungus and a photosynthetic partner co-existing in a symbiotic relationship).
An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of hexokinase, EC 2.7.1.1, an enzyme that phosphorylates hexoses forming hexose phosphate.
ATP:D-hexose 6-phosphotransferase inhibitor
ATP:D-hexose 6-phosphotransferase inhibitors
glucose ATP phosphotransferase inhibitor
glucose ATP phosphotransferase inhibitors
hexokinase type IV glucokinase inhibitor
hexokinase type IV glucokinase inhibitors
substance with EC 2.7.1.1 (hexokinase) inhibitor role
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of the enzyme lysophospholipase (EC 3.1.1.5), which catalyses the release of fatty acids from lysophospholipids.
2-lysophosphatidylcholine acylhydrolase inhibitor
2-lysophosphatidylcholine acylhydrolase inhibitors
EC 3.1.1.5 (lysophospholipase) inhibitors
lysophosphatidylcholine hydrolase inhibitor
lysophosphatidylcholine hydrolase inhibitors
lysophospholipase (EC 3.1.1.5) inhibitor
lysophospholipase (EC 3.1.1.5) inhibitors
lysophospholipase transacylase inhibitor
lysophospholipase transacylase inhibitors
substance with EC 3.1.1.5 (lysophospholipase) inhibitor role
An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of acyl-CoA dehydrogenase (NADP(+)), EC 1.3.1.8.
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitors
acyl-CoA dehydrogenase (NADP(+)) (EC 1.3.1.8) inhibitor
acyl-CoA dehydrogenase (NADP(+)) (EC 1.3.1.8) inhibitors
acyl-CoA dehydrogenase (NADP(+)) inhibitor
acyl-CoA dehydrogenase (NADP(+)) inhibitors
acyl-CoA:NADP(+) 2-oxidoreductase inhibitor
acyl-CoA:NADP(+) 2-oxidoreductase inhibitors
crotonyl coenzyme A reductase inhibitors
dehydrogenase, acyl coenzyme A (nicotinamide adenine dinucleotide phosphate) inhibitor
dehydrogenase, acyl coenzyme A (nicotinamide adenine dinucleotide phosphate) inhibitors
substance with EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor role
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7).
EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitors
UDP-N-acetylglucosamine 1-carboxyvinyl-transferase inhibitor
UDP-N-acetylglucosamine 1-carboxyvinyl-transferase inhibitors
UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) inhibitor
UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) inhibitors
UDP-N-acetylglucosamine 1-carboxyvinyltransferase inhibitor
UDP-N-acetylglucosamine 1-carboxyvinyltransferase inhibitors
UDP-N-acetylglucosamine enoylpyruvyltransferase inhibitor
UDP-N-acetylglucosamine enoylpyruvyltransferase inhibitors
phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase inhibitor
phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase inhibitors
phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase inhibitor
phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase inhibitors
phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyltransferase inhibitor
phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyltransferase inhibitors
phosphoenolpyruvate:UDP-N-acetyl-alpha-D-glucosamine 1-carboxyvinyltransferase inhibitor
phosphoenolpyruvate:UDP-N-acetyl-alpha-D-glucosamine 1-carboxyvinyltransferase inhibitors
phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase inhibitor
phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase inhibitors
phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-enolpyruvyltransferase inhibitor
phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-enolpyruvyltransferase inhibitors
phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase inhibitor
phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase inhibitors
pyruvate-UDP-acetylglucosamine transferase inhibitor
pyruvate-UDP-acetylglucosamine transferase inhibitors
pyruvate-uridine diphospho-N-acetyl-glucosamine transferase inhibitor
pyruvate-uridine diphospho-N-acetyl-glucosamine transferase inhibitors
pyruvate-uridine diphospho-N-acetylglucosamine transferase inhibitor
pyruvate-uridine diphospho-N-acetylglucosamine transferase inhibitors
pyruvic-uridine diphospho-N-acetylglucosaminyltransferase inhibitor
pyruvic-uridine diphospho-N-acetylglucosaminyltransferase inhibitors
substance with EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor role
An EC 3.5.4.* (non-peptide cyclic amidine C-N hydrolase) inhibitor that interferes with the action of cytosine deaminase (EC 3.5.4.1).
EC 3.5.4.1 (cytosine deaminase) inhibitors
cytosine deaminase (EC 3.5.4.1) inhibitor
cytosine deaminase (EC 3.5.4.1) inhibitors
substance with EC 3.5.4.1 (cytosine deaminase) inhibitor role
An EC 5.1.* (racemase/epimerase) inhibitor that interferes with the action of any such enzyme acting on hydroxy acids and their derivatives (EC 5.1.2.*).
EC 5.1.2.* (racemases acting on hydroxy acids and derivatives) inhibitors
inhibitor of racemases acting on hydroxy acids and derivatives
inhibitor of racemases acting on hydroxy acids and derivatives (EC 5.1.2.*)
inhibitors of racemases acting on hydroxy acids and derivatives
inhibitors of racemases acting on hydroxy acids and derivatives (EC 5.1.2.*)
substance with EC 5.1.2.* (racemases acting on hydroxy acids and derivatives) inhibitor role
An EC 5.1.* (racemase/epimerase) inhibitor that interferes with the action of any such enzyme acting on carbohydrates and their derivatives (EC 5.1.3.*).
EC 5.1.3.* (racemases acting on carbohydrates and derivatives) inhibitors
inhibitor of racemases acting on carbohydrates and derivatives
inhibitor of racemases acting on carbohydrates and derivatives (EC 5.1.3.*)
inhibitors of racemases acting on carbohydrates and derivatives
inhibitors of racemases acting on carbohydrates and derivatives (EC 5.1.3.*)
substance with EC 5.1.3.* (racemases acting on carbohydrates and derivatives) inhibitor role
An EC 5.1.* (racemase/epimerase) inhibitor that interferes with the action of any such enzyme acting compounds other than amino acids and their derivatives, hydroxy acids and their derivatives, or carbohydrates and their derivatives (EC 5.1.99.*).
EC 5.1.99.* (racemases acting on other compounds) inhibitors
inhibitor of racemases acting on other compounds (EC 5.1.99.*)
inhibitors of racemases acting on other compounds (EC 5.1.99.*)
substance with EC 5.1.99.* (racemases acting on other compounds) inhibitor role
An EC 5.1.3.* (racemases acting on carbohydrates and derivatives) inhibitor that interferes with the action of UDP-glucose 4-epimerase (EC 5.1.3.2).
EC 5.1.3.2 (UDP-glucose 4-epimerase) inhibitors
UDP-alpha-D-glucose 4-epimerase inhibitor
UDP-alpha-D-glucose 4-epimerase inhibitors
UDP-glucose 4-epimerase (EC 5.1.3.2) inhibitor
UDP-glucose 4-epimerase (EC 5.1.3.2) inhibitors
uridine diphosphate galactose 4-epimerase inhibitor
uridine diphosphate galactose 4-epimerase inhibitors
uridine diphosphate glucose 4-epimerase inhibitor
uridine diphosphate glucose 4-epimerase inhibitors
uridine diphospho-galactose-4-epimerase inhibitor
uridine diphospho-galactose-4-epimerase inhibitors
uridine diphosphoglucose 4-epimerase inhibitor
uridine diphosphoglucose 4-epimerase inhibitors
uridine diphosphoglucose epimerase inhibitor
uridine diphosphoglucose epimerase inhibitors
substance with EC 5.1.3.2 (UDP-glucose 4-epimerase) inhibitor role
A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a "R" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure.
Any EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that inhibits the action of carboxylesterase (EC 3.1.1.1 ).
EC 3.1.1.1 (carboxylesterase) inhibitors
substance with EC 3.1.1.1 (carboxylesterase) inhibitor role
A toxin used by animals and injected into their victims by a bite or sting.
A protein kinase agonist that selectively binds to and activates a protein kinase A receptor
substance with protein kinase A agonist role
Any agonist of one or more of the isoforms of adenylate cyclase (EC 4.6.1.1).
substance with adenylate cyclase agonist role
Any compound that causes severe skin, eye and mucosal pain and irritation.
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of any [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase (EC 2.7.11.31).
3-hydroxy-3-methylglutaryl coenzyme A reductase kinase inhibitor
3-hydroxy-3-methylglutaryl coenzyme A reductase kinase inhibitors
3-hydroxy-3-methylglutaryl-CoA reductase kinase inhibitor
3-hydroxy-3-methylglutaryl-CoA reductase kinase inhibitors
ATP:[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphotransferase inhibitor
ATP:[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphotransferase inhibitors
EC 2.7.11.31 ([hydroxymethylglutaryl-CoA reductase (NADPH)] kinase) inhibitor
EC 2.7.11.31 ([hydroxymethylglutaryl-CoA reductase (NADPH)] kinase) inhibitors
EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} inhibitors
[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase inhibitor
[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase inhibitors
[hydroxymethylglutaryl-CoA reductase (NADPH2)] kinase inhibitor
[hydroxymethylglutaryl-CoA reductase (NADPH2)] kinase inhibitors
beta-hydroxy-beta-methylglutaryl-CoA reductase kinase inhibitor
beta-hydroxy-beta-methylglutaryl-CoA reductase kinase inhibitors
hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating) inhibitor
hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating) inhibitors
hydroxymethylglutaryl coenzyme A reductase kinase inhibitor
hydroxymethylglutaryl coenzyme A reductase kinase inhibitors
hydroxymethylglutaryl-CoA reductase kinase inhibitor
hydroxymethylglutaryl-CoA reductase kinase inhibitors
substance with EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} inhibitor role
An antagonist at the bone morphogenetic protein receptor.
bone morphogenetic protein receptor inhibitors
substance with bone morphogenetic protein receptor antagonist role
Any metabolite produced by all living cells.
substance with fundamental metabolite role
An EC 4.6.* (P-O lyase) inhibitor that interferes with the action of enzyme guanylate cyclase (EC 4.6.1.2).
EC 4.6.1.2 (guanylate cyclase) inhibitors
GTP diphosphate-lyase (cyclizing) inhibitor
GTP diphosphate-lyase (cyclizing) inhibitors
GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming) inhibitor
GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming) inhibitors
substance with EC 4.6.1.2 (guanylate cyclase) inhibitor role
An antagonist that binds to and deactivates the tropomyosin-related kinase B (TrkB) receptor, the main signaling receptor of the neurotrophin brain-derived neurotrophic factor (BDNF).
tropomyosin-related kinase B receptor antagonists
substance with tropomyosin-related kinase B receptor antagonist role
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of glycylpeptide N-tetradecanoyltransferase (EC 2.3.1.97).
EC 2.3.1.97 (glycylpeptide N-tetradecanoyltransferase) inhibitors
myristoyl-CoA-protein N-myristoyltransferase inhibitor
myristoyl-CoA-protein N-myristoyltransferase inhibitors
myristoyl-coenzyme A:protein N-myristoyl transferase inhibitor
myristoyl-coenzyme A:protein N-myristoyl transferase inhibitors
peptide N-myristoyltransferase inhibitor
peptide N-myristoyltransferase inhibitors
protein N-myristoyltransferase inhibitor
protein N-myristoyltransferase inhibitors
tetradecanoyl-CoA:glycylpeptide N-tetradecanoyltransferase inhibitor
tetradecanoyl-CoA:glycylpeptide N-tetradecanoyltransferase inhibitors
substance with EC 2.3.1.97 (glycylpeptide N-tetradecanoyltransferase) inhibitor role
An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of Delta(24)-sterol reductase (EC 1.3.1.72).
Delta(24)-sterol reductase (EC 1.3.1.72) inhibitor
Delta(24)-sterol reductase (EC 1.3.1.72) inhibitors
EC 1.3.1.72 (Delta(24)-sterol reductase) inhibitors
substance with EC 1.3.1.72 (Delta(24)-sterol reductase) inhibitor role
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of methionine adenosyltransferase (EC 2.5.1.6).
ATP-methionine adenosyltransferase inhibitor
ATP-methionine adenosyltransferase inhibitors
ATP:L-methionine S-adenosyltransferase inhibitor
ATP:L-methionine S-adenosyltransferase inhibitors
EC 2.5.1.6 (methionine adenosyltransferase) inhibitors
S-adenosyl-L-methionine synthetase inhibitor
S-adenosyl-L-methionine synthetase inhibitors
S-adenosylmethionine synthase inhibitors
S-adenosylmethionine synthetase inhibitor
S-adenosylmethionine synthetase inhibitors
adenosylmethionine synthetase inhibitors
methionine S-adenosyltransferase inhibitor
methionine S-adenosyltransferase inhibitors
substance with EC 2.5.1.6 (methionine adenosyltransferase) inhibitor role
An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of sphinganine kinase (EC 2.7.1.91).
ATP:sphinganine 1-phosphotransferase inhibitor
ATP:sphinganine 1-phosphotransferase inhibitors
EC 2.7.1.91 (sphinganine kinase) inhibitor
EC 2.7.1.91 (sphinganine kinase) inhibitors
EC 2.7.1.91 (sphingosine kinase) inhibitors
dihydrosphingosine kinase (phosphorylating) inhibitor
dihydrosphingosine kinase (phosphorylating) inhibitors
sphingosine kinase (phosphorylating) inhibitor
sphingosine kinase (phosphorylating) inhibitors
substance with EC 2.7.1.91 (sphingosine kinase) inhibitor role
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of myosin-light-chain kinase (EC 2.7.11.18).
ATP:[myosin-light-chain] O-phosphotransferase inhibitor
ATP:[myosin-light-chain] O-phosphotransferase inhibitors
ATP:myosin-light-chain O-phosphotransferase inhibitor
ATP:myosin-light-chain O-phosphotransferase inhibitors
EC 2.7.11.18 (myosin-light-chain kinase) inhibitors
calcium/calmodulin-dependent myosin light chain kinase inhibitor
calcium/calmodulin-dependent myosin light chain kinase inhibitors
myosin light chain protein kinase inhibitor
myosin light chain protein kinase inhibitors
myosin light-chain kinase (phosphorylating) inhibitor
myosin light-chain kinase (phosphorylating) inhibitors
myosin-light-chain kinase (EC 2.7.11.18) inhibitor
myosin-light-chain kinase (EC 2.7.11.18) inhibitors
smooth-muscle-myosin-light-chain kinase inhibitor
smooth-muscle-myosin-light-chain kinase inhibitors
substance with EC 2.7.11.18 (myosin-light-chain kinase) inhibitor role
An animal metabolite produced by any member of the phylum Nematoda.
A nematode metabolite produced by Caenorhabditis elegans.
substance with Caenorhabditis elegans metabolite role
Any compound that affects the dimerisation of the protein survivin.
substance with survivin dimerisation modulator role
Any EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme acting on phosphorus-containing anhydrides.
EC 3.6.1.* (hydrolases acting on acid anhydrides in P-containing anhydrides) inhibitors
EC 3.6.1.* (hydrolases acting on acid anhydrides in phosphorus-containing anhydrides) inhibitor
EC 3.6.1.* (hydrolases acting on acid anhydrides in phosphorus-containing anhydrides) inhibitors
hydrolases acting on acid anhydrides in P-containing anhydrides (EC 3.6.1.*) inhibitor
hydrolases acting on acid anhydrides in P-containing anhydrides (EC 3.6.1.*) inhibitors
hydrolases acting on acid anhydrides in phosphorus-containing anhydrides (EC 3.6.1.*) inhibitor
hydrolases acting on acid anhydrides in phosphorus-containing anhydrides (EC 3.6.1.*) inhibitors
substance with EC 3.6.1.* (hydrolases acting on acid anhydrides in P-containing anhydrides) inhibitor role
An EC 3.6.1.* (hydrolases acting on acid anhydrides in P-containing anhydrides) inhibitor that interferes with the action of adenosinetriphosphatase (EC 3.6.1.3).
EC 3.6.1.3 (adenosinetriphosphatase) inhibitors
adenosinetriphosphatase (EC 3.6.1.3) inhibitor
adenosinetriphosphatase (EC 3.6.1.3) inhibitors
complex V (mitochondrial electron transport) inhibitor
complex V (mitochondrial electron transport) inhibitors
substance with EC 3.6.1.3 (adenosinetriphosphatase) inhibitor role
Any prokaryotic metabolite produced during a metabolic reaction in single-celled microorganisms, archaea.
An agonist that binds to and activates melatonin receptors.
substance with melatonin receptor agonist role
A calpain inhibitor that interferes with the action of calpain-1 (EC 3.4.22.52).
calcium-activated neutral protease I inhibitor
calcium-activated neutral protease I inhibitors
substance with EC 3.4.22.52 (calpain-1) inhibitor role
Any compound that is used as an additive to increase the plasticity or fluidity of a substance, particularly but not exclusively to synthetic polymers.
A potassium channel modulator that opens the potassium channel.
substance with potassium channel opener role
An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of gelatinase B (EC 3.4.24.35).
95 kDa type IV collagenase/gelatinase inhibitor
95 kDa type IV collagenase/gelatinase inhibitors
type IV collagen metalloproteinase inhibitor
type IV collagen metalloproteinase inhibitors
substance with EC 3.4.24.35 (gelatinase B) inhibitor role
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of mitogen-activated protein kinase (EC 2.7.11.24).
ATP:protein phosphotransferase (MAPKK-activated) inhibitor
ATP:protein phosphotransferase (MAPKK-activated) inhibitors
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitors
extracellular signal-regulated kinase inhibitor
extracellular signal-regulated kinase inhibitors
microtubule-associated protein kinase inhibitor
microtubule-associated protein kinase inhibitors
mitogen-activated protein kinase (EC 2.7.11.24) inhibitor
mitogen-activated protein kinase (EC 2.7.11.24) inhibitors
mitogen-activated protein kinase inhibitor
mitogen-activated protein kinase inhibitors
p42 mitogen-activated protein kinase inhibitor
p42 mitogen-activated protein kinase inhibitors
stress-activated protein kinase inhibitor
stress-activated protein kinase inhibitors
substance with EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor role
An EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor that interferes with the action of any such enzyme using H2O2 as acceptor and incorporating one oxygen atom of the H2O2 into the product (EC 1.11.2.*).
EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitors
substance with EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitor role
An EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitor that interferes with the action of myeloperoxidase (EC 1.11.2.2).
EC 1.11.2.2 (myeloperoxidase) inhibitors
chloride:hydrogen-peroxide oxidoreductase (hypochlorite-forming) inhibitor
chloride:hydrogen-peroxide oxidoreductase (hypochlorite-forming) inhibitors
myeloperoxidase (EC 1.11.2.2) inhibitors
substance with EC 1.11.2.2 (myeloperoxidase) inhibitor role
Any compound that is added to manufactured materials to inhibit, suppress, or delay the production of flames and so prevent the spread of fire.
A pathway inhibitor that disrupts the synthesis of glycerophosphoinositol
glycerophosphoinositol synthesis inhibitors
substance with glycerophosphoinositol synthesis inhibitor role
An EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor that interferes with the action of any tryptophan--tRNA ligase (EC 6.1.1.2).
EC 6.1.1.2 (tryptophan--tRNA ligase) inhibitors
L-tryptophan-tRNA(Trp) ligase (AMP-forming) inhibitor
L-tryptophan-tRNA(Trp) ligase (AMP-forming) inhibitors
L-tryptophan:tRNA(Trp) ligase (AMP-forming) inhibitor
L-tryptophan:tRNA(Trp) ligase (AMP-forming) inhibitors
tryptophan--tRNA ligase (EC 6.1.1.2) inhibitor
tryptophan--tRNA ligase (EC 6.1.1.2) inhibitors
tryptophanyl ribonucleic synthetase inhibitor
tryptophanyl ribonucleic synthetase inhibitors
tryptophanyl-transfer RNA synthetase inhibitor
tryptophanyl-transfer RNA synthetase inhibitors
tryptophanyl-transfer ribonucleate synthetase inhibitor
tryptophanyl-transfer ribonucleate synthetase inhibitors
tryptophanyl-transfer ribonucleic acid synthetase inhibitor
tryptophanyl-transfer ribonucleic acid synthetase inhibitors
tryptophanyl-transfer ribonucleic synthetase inhibitor
tryptophanyl-transfer ribonucleic synthetase inhibitors
substance with EC 6.1.1.2 (tryptophan--tRNA ligase) inhibitor role
A chromophore that is a linear tetrapyrrolic prosthetic group covalently attached to a large soluble protein phytochrome. Light absorption by the phytochrome chromophore triggers photoconversion between two spectrally distinct forms of the photoreceptor: Pr, the red light absorbing form, and Pfr, the far-red light absorbing form.
substance with phytochrome chromophore role
Substances that are administered to farmed animals to improve productivity by promoting weight gain, increasing muscle mass, limiting fat deposition, reducing feed consumption, and reducing waste production.
substance with animal growth promotant role
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of cyclin-dependent kinase (EC 2.7.11.22).
ATP:cyclin phosphotransferase inhibitors
Cdk-activating protein kinase inhibitors
EC 2.7.11.22 (cyclin-dependent kinase) inhibitors
cyclin-dependent protein kinase activating kinase inhibitor
cyclin-dependent protein kinase activating kinase inhibitors
substance with EC 2.7.11.22 (cyclin-dependent kinase) inhibitor role
An EC 6.1.1.* (ligases forming aminoacyl tRNA and related compounds) inhibitor that specifically inhibits the action of aspartate--tRNA ligase (EC 6.1.1.12).
EC 6.1.1.12 (aspartate--tRNA ligase) inhibitors
L-aspartate:tRNA(Asp) ligase (AMP-forming) inhibitor
L-aspartate:tRNA(Asp) ligase (AMP-forming) inhibitors
aspartyl ribonucleate synthetase inhibitor
aspartyl ribonucleate synthetase inhibitors
aspartyl ribonucleic synthetase inhibitor
aspartyl ribonucleic synthetase inhibitors
aspartyl-transfer RNA synthetase inhibitor
aspartyl-transfer RNA synthetase inhibitors
aspartyl-transfer ribonucleic acid synthetase inhibitor
aspartyl-transfer ribonucleic acid synthetase inhibitors
substance with EC 6.1.1.12 (aspartate--tRNA ligase) inhibitor role
A calpain inhibitor that interferes with the action of calpain-2 (EC 3.4.22.53).
calcium-activated neutral protease II inhibitor
calcium-activated neutral protease II inhibitors
substance with EC 3.4.22.53 (calpain-2) inhibitor role
An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of calpain-3 (EC 3.4.22.54).
calcium-activated neutral proteinase 3 inhibitor
calcium-activated neutral proteinase 3 inhibitors
muscle-specific calcium-activated neutral protease 3 inhibitor
muscle-specific calcium-activated neutral protease 3 inhibitors
substance with EC 3.4.22.54 (calpain-3) inhibitor role
An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of any calpain.
An antagonist that binds to and deactivates glucocorticoid receptors.
substance with glucocorticoid receptor antagonist role
Metabolites produced by the gut microbiota or microorganisms (e.g. bacteria and fungi) that live in the digestive tracts of animals.
substance with gut flora metabolite role
An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of neprilysin (EC 3.4.24.11).
CALLA (common acute lymphoblastic leukemia-associated) antigens inhibitor
CALLA (common acute lymphoblastic leukemia-associated) antigens inhibitors
acute lymphoblastic leukemia antigen inhibitor
acute lymphoblastic leukemia antigen inhibitors
common acute lymphoblastic leukemia antigen inhibitor
common acute lymphoblastic leukemia antigen inhibitors
common acute lymphoblastic leukemia-associated antigens inhibitor
common acute lymphoblastic leukemia-associated antigens inhibitors
kidney-brush-border neutral endopeptidase inhibitor
kidney-brush-border neutral endopeptidase inhibitors
kidney-brush-border neutral peptidase inhibitor
kidney-brush-border neutral peptidase inhibitors
kidney-brush-border neutral proteinase inhibitor
kidney-brush-border neutral proteinase inhibitors
membrane metalloendopeptidase inhibitors
substance with EC 3.4.24.11 (neprilysin) inhibitor role
An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of endothelin-converting enzyme 1 (EC 3.4.24.71).
EC 3.4.24.71 (endothelin-converting enzyme 1) inhibitors
endothelin-converting enzyme 1 (EC 3.4.24.71) inhibitor
endothelin-converting enzyme 1 (EC 3.4.24.71) inhibitors
endothelin-converting enzyme 1 inhibitor
endothelin-converting enzyme 1 inhibitors
substance with EC 3.4.24.71 (endothelin-converting enzyme 1) inhibitor role
An EC 4.1.2.* (aldehyde-lyase) inhibitor that interferes with the action of sphinganine-1-phosphate aldolase (EC 4.1.2.27).
EC 4.1.2.27 (sphinganine-1-phosphate aldolase) inhibitors
dihydrosphingosine 1-phosphate aldolase inhibitor
dihydrosphingosine 1-phosphate aldolase inhibitors
sphinganine-1-phosphate alkanal-lyase inhibitor
sphinganine-1-phosphate alkanal-lyase inhibitors
sphinganine-1-phosphate lyase inhibitors
sphinganine-1-phosphate palmitaldehyde-lyase (phosphoethanolamine-forming) inhibitor
sphinganine-1-phosphate palmitaldehyde-lyase (phosphoethanolamine-forming) inhibitors
sphinganine-1-phosphate palmitaldehyde-lyase inhibitor
sphinganine-1-phosphate palmitaldehyde-lyase inhibitors
sphingosine-1-phosphate aldolase inhibitor
sphingosine-1-phosphate aldolase inhibitors
sphingosine-1-phosphate lyase inhibitors
substance with EC 4.1.2.27 (sphinganine-1-phosphate aldolase) inhibitor role
An EC 4.1.* (C-C lyase) inhibitor that interferes with the action of any aldehyde-lyase (EC 4.1.2.*).
substance with EC 4.1.2.* (aldehyde-lyase) inhibitor role
A Daphnia metabolite produced by the species Daphnia galeata.
substance with Daphnia galeata metabolite role
An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill.
substance with crustacean metabolite role
A Daphnia metabolite produced by the species Daphnia magna.
substance with Daphnia magna metabolite role
A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia
An EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor that interferes with the action of succinate dehydrogenase (quinone), EC 1.3.5.1.
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitors
succinate dehydrogenase (ubiquinone) inhibitor
succinate dehydrogenase (ubiquinone) inhibitors
succinate dehydrogenase complex inhibitor
succinate dehydrogenase complex inhibitors
succinate:quinone oxidoreductase inhibitor
succinate:quinone oxidoreductase inhibitors
succinate:ubiquinone oxidoreductase inhibitor
succinate:ubiquinone oxidoreductase inhibitors
substance with EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor role
A semiochemical used for inter-species chemical communication in a way that benefits an individual of another species that receives the chemical signal.
A Daphnia metabolite produced by the species Daphnia pulex.
substance with Daphnia pulex metabolite role
A Daphnia metabolite produced by the species Daphnia tenebrosa.
substance with Daphnia tenebrosa metabolite role
An EC 6.2.* (C-S bond-forming ligase) inhibitor that interferes with the action of an acid-thiol ligase inhibitor (EC 6.2.1.*).
EC 6.2.1.* (acid-thiol ligase) inhibitors
EC 6.2.1.* (acid-thiol ligases) inhibitor
EC 6.2.1.* (acid-thiol ligases) inhibitors
substance with EC 6.2.1.* (acid-thiol ligase) inhibitor role
An EC 6.2.1.* (acid-thiol ligase) inhibitor that interferes with the action of a long-chain-fatty-acid--CoA ligase (EC 6.2.1.3).
EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitors
fatty acid thiokinase (long chain) inhibitor
fatty acid thiokinase (long chain) inhibitors
fatty acyl-coenzyme A synthetase inhibitor
fatty acyl-coenzyme A synthetase inhibitors
long chain fatty acyl-CoA synthetase inhibitor
long chain fatty acyl-CoA synthetase inhibitors
long-chain acyl CoA synthetase inhibitor
long-chain acyl CoA synthetase inhibitors
long-chain acyl-CoA synthetase I inhibitor
long-chain acyl-CoA synthetase I inhibitors
long-chain acyl-CoA synthetase II inhibitor
long-chain acyl-CoA synthetase II inhibitors
long-chain acyl-coenzyme A synthetase inhibitor
long-chain acyl-coenzyme A synthetase inhibitors
long-chain fatty acid:CoA ligase (AMP-forming) inhibitor
long-chain fatty acid:CoA ligase (AMP-forming) inhibitors
long-chain fatty acyl coenzyme A synthetase inhibitor
long-chain fatty acyl coenzyme A synthetase inhibitors
palmitoyl coenzyme A synthetase inhibitor
palmitoyl coenzyme A synthetase inhibitors
substance with EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor role
An antagonist that binds to and deactivates orexin receptors.
substance with orexin receptor antagonist role
An antagonist at the protease-activated receptor-1.
coagulation factor II (thrombin) receptor antagonist
coagulation factor II (thrombin) receptor antagonists
coagulation factor II receptor antagonist
coagulation factor II receptor antagonists
coagulation factor II thrombin receptor antagonist
coagulation factor II thrombin receptor antagonists
protease activated receptor 1 antagonist
protease activated receptor 1 antagonists
protease-activated receptor 1 antagonist
protease-activated receptor 1 antagonists
protease-activated receptor-1 antagonists
proteinase-activated receptor 1 antagonist
proteinase-activated receptor 1 antagonists
substance with protease-activated receptor-1 antagonist role
An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of methylsterol monooxygenase (EC 1.14.13.72).
4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,NAD(P)H:oxygen oxidoreductase (hydroxylating) inhibitor
4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,NAD(P)H:oxygen oxidoreductase (hydroxylating) inhibitors
4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating) inhibitor
4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating) inhibitors
EC 1.14.13.72 (ethylsterol monooxygenase) inhibitors
methylsterol monooxygenase (EC 1.14.13.72) inhibitor
methylsterol monooxygenase (EC 1.14.13.72) inhibitors
substance with EC 1.14.13.72 (methylsterol monooxygenase) inhibitor role
Any compound that inhibits the biosynthesis of any sterol.
substance with sterol biosynthesis inhibitor role
An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of Delta(14)-sterol reductase (EC 1.3.1.70).
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP(+) Delta(14)-oxidoreductase inhibitor
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP(+) Delta(14)-oxidoreductase inhibitors
Delta(14)-sterol reductase (EC 1.3.1.70) inhibitor
Delta(14)-sterol reductase (EC 1.3.1.70) inhibitors
EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitors
substance with EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitor role
Any metabolite produced by metabolism of a xenobiotic compound in marine macro- and microorganisms.
substance with marine xenobiotic metabolite role
Any agent capable of inducing steatosis, a pathological condition characterised by accumulation or abnormal retention of fats within a cell.
substance with steatosis inducing agent role
Any hepatotoxic agent capable of inducing liver steatosis or fatty liver disease.
substance with hepatic steatosis inducing agent role
A sterol biosynthesis inhibitor that acts by inhibiting the C14 demethylation step within fungal steroid biosynthesis.
substance with sterol demethylation inhibitor role
Any compound that inhibits the biosynthesis of any phospholipid.
substance with phospholipid biosynthesis inhibitor role
An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of alpha,alpha-trehalose phosphorylase (configuration-retaining) (EC 2.4.1.231).
EC 2.4.1.231 [alpha,alpha-trehalose phosphorylase (configuration-retaining)] inhibitors
alpha,alpha-trehalose phosphorylase (configuration-retaining) (EC 2.4.1.231) inhibitor
alpha,alpha-trehalose phosphorylase (configuration-retaining) (EC 2.4.1.231) inhibitors
alpha,alpha-trehalose phosphorylase (configuration-retaining) inhibitor
alpha,alpha-trehalose phosphorylase (configuration-retaining) inhibitors
alpha,alpha-trehalose:phosphate alpha-D-glucosyltransferase inhibitor
alpha,alpha-trehalose:phosphate alpha-D-glucosyltransferase inhibitors
substance with EC 2.4.1.231 [alpha,alpha-trehalose phosphorylase (configuration-retaining)] inhibitor role
An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of alpha,alpha-trehalose phosphorylase (EC 2.4.1.64).
EC 2.4.1.64 (alpha,alpha-trehalose phosphorylase) inhibitors
alpha,alpha-trehalose phosphorylase (EC 2.4.1.64) inhibitor
alpha,alpha-trehalose phosphorylase (EC 2.4.1.64) inhibitors
alpha,alpha-trehalose phosphorylase inhibitor
alpha,alpha-trehalose phosphorylase inhibitors
alpha,alpha-trehalose:phosphate beta-D-glucosyltransferase inhibitor
alpha,alpha-trehalose:phosphate beta-D-glucosyltransferase inhibitors
substance with EC 2.4.1.64 (alpha,alpha-trehalose phosphorylase) inhibitor role
An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of alpha,alpha-trehalase (EC 2.4.1.28).
EC 3.2.1.28 (alpha,alpha-trehalase) inhibitors
alpha,alpha-trehalase (EC 3.2.1.28) inhibitor
alpha,alpha-trehalase (EC 3.2.1.28) inhibitors
substance with EC 3.2.1.28 (alpha,alpha-trehalase) inhibitor role
Any inhibitor of nonstructural protein 5A.
HCV non-structural protein 5A inhibitors
substance with nonstructural protein 5A inhibitor role
An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of scytalone dehydratase (EC 4.2.1.94).
EC 4.2.1.94 (scytalone dehydratase) inhibitors
scytalone 7,8-hydro-lyase (1,3,8-trihydroxynaphthalene-forming) inhibitor
scytalone 7,8-hydro-lyase (1,3,8-trihydroxynaphthalene-forming) inhibitors
substance with EC 4.2.1.94 (scytalone dehydratase) inhibitor role
An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of gelatinase A (EC 3.4.24.24).
type IV collagenase/gelatinase inhibitor
type IV collagenase/gelatinase inhibitors
substance with EC 3.4.24.24 (gelatinase A) inhibitor role
Any metabolite (endogenous or exogenous) found in human urine samples.
substance with human urinary metabolite role
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of nicotinamidase (EC 3.5.1.19).
substance with EC 3.5.1.19 (nicotinamidase) inhibitor role
An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of peptidase K (EC 3.4.21.64).
Tritirachium album proteinase K inhibitor
Tritirachium album proteinase K inhibitors
Tritirachium album serine proteinase inhibitor
Tritirachium album serine proteinase inhibitors
substance with EC 3.4.21.64 (peptidase K) inhibitor role
Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae.
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of arylamine N-acetyltransferase (EC 2.3.1.5).
2-naphthylamine N-acetyltransferase inhibitor
2-naphthylamine N-acetyltransferase inhibitors
4-aminobiphenyl N-acetyltransferase inhibitor
4-aminobiphenyl N-acetyltransferase inhibitors
EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitors
acetyl CoA-arylamine N-acetyltransferase inhibitor
acetyl CoA-arylamine N-acetyltransferase inhibitors
acetyl-CoA:arylamine N-acetyltransferase inhibitor
acetyl-CoA:arylamine N-acetyltransferase inhibitors
arylamine N-acetyltransferase (EC 2.3.1.5) inhibitor
arylamine N-acetyltransferase (EC 2.3.1.5) inhibitors
arylamine N-acetyltransferase inhibitors
beta-naphthylamine N-acetyltransferase inhibitor
beta-naphthylamine N-acetyltransferase inhibitors
indoleamine N-acetyltransferase inhibitor
indoleamine N-acetyltransferase inhibitors
p-aminosalicylate N-acetyltransferase inhibitor
p-aminosalicylate N-acetyltransferase inhibitors
serotonin N-acetyltransferase inhibitors
substance with EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitor role
Any EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of glycogen phosphorylase (EC 2.4.1.1).
(1->4)-alpha-D-glucan:phosphate alpha-D-glucosyltransferase inhibitor
(1->4)-alpha-D-glucan:phosphate alpha-D-glucosyltransferase inhibitors
1,4-alpha-D-glucan:phosphate alpha-D-glucosyltransferase inhibitor
1,4-alpha-D-glucan:phosphate alpha-D-glucosyltransferase inhibitors
1,4-alpha-glucan phosphorylase inhibitor
1,4-alpha-glucan phosphorylase inhibitors
EC 2.4.1.1 (glycogen phosphorylase) inhibitors
glycogen phosphorylase (EC 2.4.1.1) inhibitor
glycogen phosphorylase (EC 2.4.1.1) inhibitors
substance with EC 2.4.1.1 (glycogen phosphorylase) inhibitor role
Any EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of inositol-trisphosphate 3-kinase (EC 2.7.1.127).
1D-myo-inositol-trisphosphate 3-kinase inhibitor
1D-myo-inositol-trisphosphate 3-kinase inhibitors
ATP:1D-myo-inositol-1,4,5-trisphosphate 3-phosphotransferase inhibitor
ATP:1D-myo-inositol-1,4,5-trisphosphate 3-phosphotransferase inhibitors
EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitors
inositol 1,4,5-trisphosphate 3-kinase inhibitor
inositol 1,4,5-trisphosphate 3-kinase inhibitors
inositol-trisphosphate 3-kinase (EC 2.7.1.127) inhibitor
inositol-trisphosphate 3-kinase (EC 2.7.1.127) inhibitors
inositol-trisphosphate 3-kinase inhibitor
inositol-trisphosphate 3-kinase inhibitors
substance with EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor role
Any EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of inositol-polyphosphate multikinase (EC 2.7.1.151).
ATP:1D-myo-inositol-1,4,5-trisphosphate 6-phosphotransferase inhibitor
ATP:1D-myo-inositol-1,4,5-trisphosphate 6-phosphotransferase inhibitors
EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitors
IP3/IP4 dual-specificity 6-/3-kinase inhibitor
IP3/IP4 dual-specificity 6-/3-kinase inhibitors
inositol polyphosphate 6-/3-/5-kinase inhibitor
inositol polyphosphate 6-/3-/5-kinase inhibitors
inositol-polyphosphate multikinase (EC 2.7.1.151) inhibitor
inositol-polyphosphate multikinase (EC 2.7.1.151) inhibitors
inositol-polyphosphate multikinase inhibitor
inositol-polyphosphate multikinase inhibitors
substance with EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitor role
Any EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any phosphotransferase with a phosphate group as acceptor (EC 2.7.4.*).
EC 2.7.4.* (phosphotransferases with a phosphate group as acceptor) inhibitors
phosphotransferases with a phosphate group as acceptor (EC 2.7.4.*) inhibitor
phosphotransferases with a phosphate group as acceptor (EC 2.7.4.*) inhibitors
substance with EC 2.7.4.* (phosphotransferases with a phosphate group as acceptor) inhibitor role
Any EC 2.7.4.* (phosphotransferases with a phosphate group as acceptor) inhibitor that interferes with the action of nucleoside-diphosphate kinase (EC 2.7.4.6).
ATP:nucleoside-diphosphate phosphotransferase inhibitor
ATP:nucleoside-diphosphate phosphotransferase inhibitors
EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitors
nucleoside 5'-diphosphate kinase inhibitor
nucleoside 5'-diphosphate kinase inhibitors
nucleoside diphosphate (UDP) kinase inhibitor
nucleoside diphosphate (UDP) kinase inhibitors
nucleoside-diphosphate kinase (EC 2.7.4.6) inhibitor
nucleoside-diphosphate kinase (EC 2.7.4.6) inhibitors
nucleoside-diphosphate kinase inhibitors
substance with EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor role
An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of glutamine--fructose-6-phosphate transaminase (isomerizing) (EC 2.6.1.19).
D-fructose-6-phosphate amidotransferase inhibitor
D-fructose-6-phosphate amidotransferase inhibitors
EC 2.6.1.16 (glutamine--fructose-6-phosphate transaminase (isomerizing)) inhibitors
L-glutamine-D-fructose-6-phosphate amidotransferase inhibitor
L-glutamine-D-fructose-6-phosphate amidotransferase inhibitors
L-glutamine:D-fructose-6-phosphate isomerase (deaminating) inhibitor
L-glutamine:D-fructose-6-phosphate isomerase (deaminating) inhibitors
glucosamine 6-phosphate synthase inhibitor
glucosamine 6-phosphate synthase inhibitors
glucosamine-6-phosphate isomerase (glutamine-forming) inhibitor
glucosamine-6-phosphate isomerase (glutamine-forming) inhibitors
glucosamine-6-phosphate synthase inhibitor
glucosamine-6-phosphate synthase inhibitors
glucosaminephosphate isomerase inhibitor
glucosaminephosphate isomerase inhibitors
hexosephosphate aminotransferase inhibitor
hexosephosphate aminotransferase inhibitors
substance with EC 2.6.1.16 (glutamine--fructose-6-phosphate transaminase (isomerizing)) inhibitor role
An agonist that selectively binds to and activates the thrombopoietin receptor [myeloproliferative leukemia protein or CD110 (Cluster of Differentiation 110)].
substance with thrombopoietin receptor agonist role
Any cosmetic used to lighten the colour of skin by reducing the concentration of melanin.
substance with skin lightening agent role
An EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.10.3.*).
EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitors
substance with EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor role
Any EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor that interferes with the action of catechol oxidase (EC 1.10.3.1).
1,2-benzenediol:oxygen oxidoreductase inhibitor
1,2-benzenediol:oxygen oxidoreductase inhibitors
EC 1.10.3.1 (catechol oxidase) inhibitors
catechol oxidase (EC 1.10.3.1) inhibitor
catechol oxidase (EC 1.10.3.1) inhibitors
o-diphenol:oxygen oxidoreductase inhibitor
o-diphenol:oxygen oxidoreductase inhibitors
substance with EC 1.10.3.1 (catechol oxidase) inhibitor role
Any EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor that interferes with the action of laccase (EC 1.10.3.2).
benzenediol:oxygen oxidoreductase inhibitor
benzenediol:oxygen oxidoreductase inhibitors
substance with EC 1.10.3.2 (laccase) inhibitor role
Any EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor that interferes with the action of quercetin 2,3-dioxygenase (EC 1.13.1.24).
EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitors
quercetin 2,3-dioxygenase (EC 1.13.11.24) inhibitor
quercetin 2,3-dioxygenase (EC 1.13.11.24) inhibitors
quercetin:oxygen 2,3-oxidoreductase (decyclising) inhibitor
quercetin:oxygen 2,3-oxidoreductase (decyclising) inhibitors
quercetin:oxygen 2,3-oxidoreductase (decyclizing) inhibitor
quercetin:oxygen 2,3-oxidoreductase (decyclizing) inhibitors
quercetin:oxygen 2,3-oxidoreductase (ring-opening) inhibitor
quercetin:oxygen 2,3-oxidoreductase (ring-opening) inhibitors
substance with EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitor role
Any EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of D-amino-acid oxidase (EC 1.4.3.3).
D-amino-acid oxidase (EC 1.4.3.3) inhibitor
D-amino-acid oxidase (EC 1.4.3.3) inhibitors
D-amino-acid:oxygen oxidoreductase (deaminating) inhibitor
D-amino-acid:oxygen oxidoreductase (deaminating) inhibitors
EC 1.4.3.3 (D-amino-acid oxidase) inhibitors
L-amino acid:O2 oxidoreductase inhibitor
L-amino acid:O2 oxidoreductase inhibitors
substance with EC 1.4.3.3 (D-amino-acid oxidase) inhibitor role
Any compound that binds to and activates the enzyme [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase (EC 2.7.11.31).
3-hydroxy-3-methylglutaryl coenzyme A reductase kinase activator
3-hydroxy-3-methylglutaryl coenzyme A reductase kinase activators
3-hydroxy-3-methylglutaryl-CoA reductase kinase activator
3-hydroxy-3-methylglutaryl-CoA reductase kinase activators
ATP:[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphotransferase activator
ATP:[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphotransferase activators
EC 2.7.11.31 ([hydroxymethylglutaryl-CoA reductase (NADPH)] kinase) activator
EC 2.7.11.31 ([hydroxymethylglutaryl-CoA reductase (NADPH)] kinase) activators
EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} activators
[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activator
[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activators
[hydroxymethylglutaryl-CoA reductase (NADPH2)] kinase activator
[hydroxymethylglutaryl-CoA reductase (NADPH2)] kinase activators
beta-hydroxy-beta-methylglutaryl-CoA reductase kinase activator
beta-hydroxy-beta-methylglutaryl-CoA reductase kinase activators
hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating) activator
hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating) activators
hydroxymethylglutaryl coenzyme A reductase kinase activator
hydroxymethylglutaryl coenzyme A reductase kinase activators
hydroxymethylglutaryl-CoA reductase kinase activator
hydroxymethylglutaryl-CoA reductase kinase activators
substance with EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} activator role
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of cAMP-dependent protein kinase (EC 2.7.11.11).
ATP:protein phosphotransferase (cAMP-dependent) inhibitor
ATP:protein phosphotransferase (cAMP-dependent) inhibitors
EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitors
cAMP-dependent protein kinase (EC 2.7.11.11) inhibitor
cAMP-dependent protein kinase (EC 2.7.11.11) inhibitors
substance with EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor role
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of cGMP-dependent protein kinase (EC 2.7.11.12).
3':5'-cyclic GMP-dependent protein kinase inhibitor
3':5'-cyclic GMP-dependent protein kinase inhibitors
ATP:protein phosphotransferase (cGMP-dependent) inhibitor
ATP:protein phosphotransferase (cGMP-dependent) inhibitors
EC 2.7.11.12 (cGMP-dependent protein kinase) inhibitors
cGMP-dependent protein kinase (EC 2.7.11.12) inhibitor
cGMP-dependent protein kinase (EC 2.7.11.12) inhibitors
cGMP-dependent protein kinase Ibeta inhibitor
cGMP-dependent protein kinase Ibeta inhibitors
guanosine 3':5'-cyclic monophosphate-dependent protein kinase inhibitor
guanosine 3':5'-cyclic monophosphate-dependent protein kinase inhibitors
substance with EC 2.7.11.12 (cGMP-dependent protein kinase) inhibitor role
Any inhibitor of nonnucleoside hepatitis C virus polymerase.
nonnucleoside hepatitis C virus polymerase inhibitors
substance with nonnucleoside hepatitis C virus polymerase inhibitor role
Any inhibitor of hepatitis C virus nonstructural protein 5A.
hepatitis C virus nonstructural protein 5A inhibitors
substance with hepatitis C virus nonstructural protein 5A inhibitor role
Any metabolite (endogenous or exogenous) found in human blood serum samples.
substance with human blood serum metabolite role
A compound that inhibits the re-uptake of the neurotransmitter GABA from the synapse into the pre-synaptic neuron, so increasing the extracellular concentrations of the neurotransmitter and hence increasing neurotransmission.
gamma-aminobutyric acid re-uptake inhibitor
gamma-aminobutyric acid re-uptake inhibitors
gamma-aminobutyric acid reuptake inhibitor
gamma-aminobutyric acid reuptake inhibitors
substance with GABA reuptake inhibitor role
Any glycine transporter inhibitor that interferes with the action of glycine 2 transporters.
substance with glycine transporter 2 inhibitor role
Any substance that inhibits the action of glycine transporters.
substance with glycine transporter inhibitor role
An antagonist that binds to and deactivates thromboxane A2 receptors.
substance with thromboxane A2 antagonist role
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific].
(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 8 isopentenyl units) inhibitor
(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 8 isopentenyl units) inhibitors
EC 2.5.1.31 {ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]} inhibitors
bactoprenyl-diphosphate synthase inhibitor
bactoprenyl-diphosphate synthase inhibitors
ditrans,polycis-undecaprenyl-diphosphate synthase inhibitor
ditrans,polycis-undecaprenyl-diphosphate synthase inhibitors
ditrans,polycis-undecaprenylcistransferase inhibitor
ditrans,polycis-undecaprenylcistransferase inhibitors
undecaprenyl diphosphate synthetase inhibitor
undecaprenyl diphosphate synthetase inhibitors
undecaprenyl pyrophosphate synthase inhibitor
undecaprenyl pyrophosphate synthase inhibitors
undecaprenyl pyrophosphate synthetase inhibitor
undecaprenyl pyrophosphate synthetase inhibitors
undecaprenyl-diphosphate synthase inhibitor
undecaprenyl-diphosphate synthase inhibitors
substance with EC 2.5.1.31 {ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]} inhibitor role
Any EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action any such enzyme that has NAD(+) or NADP(+) as acceptor.
EC 1.4.1.* (oxidoreductase acting on donor CH-NH2 group with NAD(+) or NADP(+) as acceptor) inhibitor
EC 1.4.1.* (oxidoreductase acting on donor CH-NH2 group with NAD(+) or NADP(+) as acceptor) inhibitors
EC 1.4.1.* (oxidoreductase acting on donor CH-NH2 group; NAD(+) or NADP(+) as acceptor) inhibitors
substance with EC 1.4.1.* (oxidoreductase acting on donor CH-NH2 group; NAD(+) or NADP(+) as acceptor) inhibitor role
An EC 1.4.1.* (oxidoreductase acting on donor CH-NH2 group; NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of glutamate dehydrogenase [NAD(P)(+)] (EC 1.4.1.3).
EC 1.4.1.3 {glutamate dehydrogenase [NAD(P)(+)]} inhibitors
L-glutamate:NAD(P)(+) oxidoreductase (deaminating) inhibitor
L-glutamate:NAD(P)(+) oxidoreductase (deaminating) inhibitors
glutamate dehydrogenase [NAD(P)(+)] (EC 1.4.1.3) inhibitor
glutamate dehydrogenase [NAD(P)(+)] (EC 1.4.1.3) inhibitors
glutamate dehydrogenase [NAD(P)(+)] inhibitor
glutamate dehydrogenase [NAD(P)(+)] inhibitors
substance with EC 1.4.1.3 {glutamate dehydrogenase [NAD(P)(+)]} inhibitor role
Any compound that acts as an agonist towards the liver X receptors.
substance with liver X receptor agonist role
Any mammalian metabolite produced during a metabolic reaction in rat (Rattus norvegicus).
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties.
substance with antifungal agrochemical role
An EC 5.3.* (intramolecular oxidoreductase) inhibitor that inhibits the action of any such enzyme that transposes C=C bonds (EC 5.3.3.*).
EC 5.3.3.* (intramolecular oxidase transposing C=C bonds) inhibitors
intramolecular oxidase transposing C=C bonds inhibitor (EC 5.3.3.*) inhibitor
intramolecular oxidase transposing C=C bonds inhibitor (EC 5.3.3.*) inhibitors
substance with EC 5.3.3.* (intramolecular oxidase transposing C=C bonds) inhibitor role
An EC 5.3.3.* (intramolecular oxidase transposing C=C bonds) inhibitor that interferes with the action of a cholestenol Delta-isomerase (EC 5.3.3.5).
Delta(7)-cholestenol Delta(7)-Delta(8)-isomerase inhibitor
Delta(7)-cholestenol Delta(7)-Delta(8)-isomerase inhibitors
EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitors
cholestenol Delta-isomerase (EC 5.3.3.5) inhibitor
cholestenol Delta-isomerase (EC 5.3.3.5) inhibitors
substance with EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor role
An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of ent-kaurene oxidase (E.C. 1.14.13.78).
EC 1.14.13.78 (ent-kaurene oxidase) inhibitors
ent-kaurene oxidase (EC 1.14.13.78) inhibitor
ent-kaurene oxidase (EC 1.14.13.78) inhibitors
substance with EC 1.14.13.78 (ent-kaurene oxidase) inhibitor role
An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of EC 1.14.13.97 (taurochenodeoxycholate 6alpha-hydroxylase).
EC 1.14.13.97 (taurochenodeoxycholate 6alpha-hydroxylase) inhibitors
taurochenodeoxycholate 6alpha-hydroxylase inhibitor
taurochenodeoxycholate 6alpha-hydroxylase inhibitors
taurochenodeoxycholate 6alpha-monooxygenase inhibitor
taurochenodeoxycholate 6alpha-monooxygenase inhibitors
taurochenodeoxycholate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating) inhibitor
taurochenodeoxycholate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating) inhibitors
substance with EC 1.14.13.97 (taurochenodeoxycholate 6alpha-hydroxylase) inhibitor role
Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of endopeptidase Clp (EC 3.4.21.92).
EC 3.4.21.92 (endopeptidase Clp) inhibitors
substance with EC 3.4.21.92 (endopeptidase Clp) inhibitor role
An inhibitor of signal transducer and activator of transcription 3 (STAT3)
signal transducer and activator of transcription 3 inhibitor
signal transducer and activator of transcription 3 inhibitors
Mothers against decapentaplegic homolog 3 inhibitors
Mothers against decapentaplegic homologue 3 inhibitor
Mothers against decapentaplegic homologue 3 inhibitors
mothers against decapentaplegic homolog 3 inhibitor
Any inhibitor of signal transducer and activator of transcription 5 protein
signal transducer and activator of transcription 5 protein inhibitors
substance with signal transducer and activator of transcription 5 protein inhibitor role
Any toxin produced by cyanobacteria (blue-green algae).
Any drug which causes the onset of an allergic reaction.
Any ionophore capable of transportation of potassium ions across membranes.
Any compound that inhibits the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell).
An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of duals specificity kinases acting on Ser/Thr and Tyr residues.
EC 2.7.12.* [dual-specificity kinases (those acting on Ser/Thr and Tyr residues)] inhibitors
inhibitor of dual-specificity kinases (those acting on Ser/Thr and Tyr residues) (EC 2.7.12.*)
inhibitors of dual-specificity kinases (those acting on Ser/Thr and Tyr residues) (EC 2.7.12.*)
substance with EC 2.7.12.* [dual-specificity kinases (those acting on Ser/Thr and Tyr residues)] inhibitor role
An EC 2.7.12.* [dual-specificity kinases (those acting on Ser/Thr and Tyr residues)] inhibitor that inhibits the action of mitogen-activated protein kinase kinase (EC 2.7.12.2).
ATP:protein phosphotransferase (MAPKKK-activated) inhibitor
ATP:protein phosphotransferase (MAPKKK-activated) inhibitors
EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitors
mitogen-activated protein kinase kinase (EC 2.7.12.2) inhibitor
mitogen-activated protein kinase kinase (EC 2.7.12.2) inhibitors
mitogen-activated protein kinase kinase inhibitor
mitogen-activated protein kinase kinase inhibitors
substance with EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitor role
An antagonist at G-protein-coupled receptor.
substance with G-protein-coupled receptor antagonist role
Any retinoic acid receptor (RAR) agonist with specificity for RARgamma.
nuclear receptor subfamily 1, group B, member 3 agonist
nuclear receptor subfamily 1, group B, member 3 agonists
substance with retinoic acid receptor gamma agonist role
An activator of alpha-secretase, one of the three endopeptidases that are specific for amyloid protein precursor and which have been identified based upon the region of the amyloid protein precursor which they cleave.
substance with alpha-secretase activator role
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) (EC 1.1.1.170).
3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) inhibitor
3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) inhibitors
3beta-hydroxy-4beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) inhibitor
3beta-hydroxy-4beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) inhibitors
3beta-hydroxy-4beta-methylcholestenoate dehydrogenase inhibitor
3beta-hydroxy-4beta-methylcholestenoate dehydrogenase inhibitors
3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) (EC 1.1.1.170) inhibitor
3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) (EC 1.1.1.170) inhibitors
3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) inhibitor
3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) inhibitors
3beta-hydroxysteroid-4alpha-carboxylate:NAD(P)(+) 3-oxidoreductase (decarboxylating) inhibitor
3beta-hydroxysteroid-4alpha-carboxylate:NAD(P)(+) 3-oxidoreductase (decarboxylating) inhibitors
EC 1.1.1.170 [3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)] inhibitors
sterol 4alpha-carboxylic decarboxylase inhibitor
sterol 4alpha-carboxylic decarboxylase inhibitors
sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating) inhibitor
sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating) inhibitors
substance with EC 1.1.1.170 [3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)] inhibitor role
An EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor that inhibits the action of c-Jun N-terminal kinase.
substance with c-Jun N-terminal kinase inhibitor role
An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of DNA (cytosine-5-)-methyltransferase (EC 2.1.1.37).
DNA-cytosine methyltransferase inhibitor
DNA-cytosine methyltransferase inhibitors
EC 2.1.1.37 [DNA (cytosine-5-)-methyltransferase] inhibitors
S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase inhibitor
S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase inhibitors
cytosine DNA methyltransferase inhibitor
cytosine DNA methyltransferase inhibitors
cytosine-specific DNA methyltransferase inhibitor
cytosine-specific DNA methyltransferase inhibitors
deoxyribonucleate methyltransferase inhibitor
deoxyribonucleate methyltransferase inhibitors
deoxyribonucleic (cytosine-5-)-methyltransferase inhibitor
deoxyribonucleic (cytosine-5-)-methyltransferase inhibitors
deoxyribonucleic acid (cytosine-5-)-methyltransferase inhibitor
deoxyribonucleic acid (cytosine-5-)-methyltransferase inhibitors
deoxyribonucleic acid methylase inhibitor
deoxyribonucleic acid methylase inhibitors
deoxyribonucleic acid methyltransferase inhibitor
deoxyribonucleic acid methyltransferase inhibitors
deoxyribonucleic acid modification methylase inhibitor
deoxyribonucleic acid modification methylase inhibitors
methylphosphotriester-DNA methyltransferase inhibitor
methylphosphotriester-DNA methyltransferase inhibitors
site-specific DNA-methyltransferase (cytosine-specific) inhibitor
site-specific DNA-methyltransferase (cytosine-specific) inhibitors
substance with EC 2.1.1.37 [DNA (cytosine-5-)-methyltransferase] inhibitor role
An EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor that interferes with the action of c-Met tyrosine kinase.
MET proto-oncogene, receptor tyrosine kinase inhibitor
MET proto-oncogene, receptor tyrosine kinase inhibitors
substance with c-Met tyrosine kinase inhibitor role
Any EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of orotidine-5'-phosphate decarboxylase (EC 4.1.1.23).
EC 4.1.1.23 (orotidine-5'-phosphate decarboxylase) inhibitors
orotate monophosphate decarboxylase inhibitor
orotate monophosphate decarboxylase inhibitors
orotidine 5'-phosphate decarboxylase inhibitor
orotidine 5'-phosphate decarboxylase inhibitors
orotidine monophosphate decarboxylase inhibitor
orotidine monophosphate decarboxylase inhibitors
orotidine phosphate decarboxylase inhibitor
orotidine phosphate decarboxylase inhibitors
orotidine-5'-monophosphate decarboxylase inhibitor
orotidine-5'-monophosphate decarboxylase inhibitors
orotidine-5'-phosphate carboxy-lyase (UMP-forming) inhibitor
orotidine-5'-phosphate carboxy-lyase (UMP-forming) inhibitors
orotidine-5'-phosphate carboxy-lyase inhibitor
orotidine-5'-phosphate carboxy-lyase inhibitors
orotidine-5'-phosphate decarboxylase (EC 4.1.1.23) inhibitor
orotidine-5'-phosphate decarboxylase (EC 4.1.1.23) inhibitors
orotidylic acid decarboxylase inhibitors
uridine 5'-monophosphate synthase inhibitor
uridine 5'-monophosphate synthase inhibitors
substance with EC 4.1.1.23 (orotidine-5'-phosphate decarboxylase) inhibitor role
An EC 6.4.1.* (carboxylase) inhibitor that interferes with the action of pyruvate carboxylase (EC 6.4.1.1).
EC 6.4.1.1 (pyruvate carboxylase) inhibitors
pyruvate carboxylase (EC 6.4.1.1) inhibitor
pyruvate carboxylase (EC 6.4.1.1) inhibitors
pyruvate:carbon-dioxide ligase (ADP-forming) inhibitor
pyruvate:carbon-dioxide ligase (ADP-forming) inhibitors
substance with EC 6.4.1.1 (pyruvate carboxylase) inhibitor role
An EC 4.6.* (P-O lyase) inhibitor that interferes with the action of enzyme adenylate cyclase (EC 4.6.1.1).
ATP diphosphate-lyase (cyclising) inhibitor
ATP diphosphate-lyase (cyclising) inhibitors
ATP diphosphate-lyase (cyclising; 3',5'-cyclic-AMP-forming) inhibitor
ATP diphosphate-lyase (cyclising; 3',5'-cyclic-AMP-forming) inhibitors
ATP diphosphate-lyase (cyclizing) inhibitor
ATP diphosphate-lyase (cyclizing) inhibitors
ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming) inhibitor
ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming) inhibitors
EC 4.6.1.1 (adenylate cyclase) inhibitors
adenylate cyclase (EC 4.6.1.1) inhibitor
adenylate cyclase (EC 4.6.1.1) inhibitors
substance with EC 4.6.1.1 (adenylate cyclase) inhibitor role
Any compound that binds to and activates the enzyme histone acetyltransferase (EC 2.3.1.48).
substance with histone acetyltransferase activator role
An EC 3.5.1.98 (histone deacetylase) inhibitor that interferes with the action of Sir1.
A substance that causes another substance to be secreted.
A secretagogue that causes the secretion of insulin.
substance with insulin secretagogue role
substance with EC 5.3.1.* (intramolecular oxidoreductase interconverting aldoses and ketoses) inhibitor role
Any EC 5.3.1.* (intramolecular oxidoreductase interconverting aldoses and ketoses) inhibitor that interferes with the action of a triose-phosphate isomerase (EC 5.3.1.1).
D-glyceraldehyde-3-phosphate ketol-isomerase inhibitor
D-glyceraldehyde-3-phosphate ketol-isomerase inhibitors
EC 5.3.1.1 (triose-phosphate isomerase) inhibitors
triose-phosphate isomerase (EC 5.3.1.1) inhibitor
triose-phosphate isomerase (EC 5.3.1.1) inhibitors
substance with EC 5.3.1.1 (triose-phosphate isomerase) inhibitor role
A nuclear receptor modulator that affects the retinoic acid receptor
substance with retinoic acid receptor modulator role
Any receptor modulator acting on nuclear receptors
substance with nuclear receptor modulator role
A drug that acts as an antagonist, agonist, reverse agonist, or in some other fashion when interacting with cellular receptors.
A retinoic acid receptor antagonist that antagonises retinoic acid receptor alpha.
retinoic acid receptor alpha antagonists
substance with retinoic acid receptor alpha antagonist role
An antagonist that acts at the retinoic acid receptor.
substance with retinoic acid receptor antagonist role
Any retinoic acid receptor (RAR) agonist with specificity for RARbeta.
substance with retinoic acid receptor beta agonist role
A retinoic acid receptor antagonist that antagonises retinoic acid receptor gamma.
retinoic acid receptor gamma antagonists
substance with retinoic acid receptor gamma antagonist role
A role borne by a molecule that acts to counteract or neutralize the deleterious effects of cyanide.
substance with antidote to cyanide poisoning role
A role borne by a molecule that acts to counteract or neutralise the deleterious effects of organophosphates or acetylcholinesterase inhibitors (nerve agents).
antidote to acetylcholinesterase inhibitor poisoning
substance with antidote to organophosphate poisoning role
A role borne by a molecule that acts to counteract or neutralise the deleterious effects of opioids.
substance with antidote to opioid poisoning role
A role borne by a molecule that acts to counteract or neutralise the deleterious effects of benzodiazepines.
substance with antidote to benzodiazepine poisoning role
Any compound that inihibits the human protein, eukaryotic translation elongation factor 1alpha 1.
eukaryotic translation elongation factor 1alpha 1 inhibitors
substance with eukaryotic translation elongation factor 1alpha 1 inhibitor role
A serine/threonine kinase inhibitor that specifically inhibits RAC-alpha serine/threonine-protein kinase (ATK1).
RAC-alpha serine/threonine-protein kinase inhibitor
RAC-alpha serine/threonine-protein kinase inhibitors
substance with AKT1 kinase inhibitor role
An agonist that binds to and activates prostacyclin receptors
substance with prostacyclin receptor agonist role
An inverse agonist that binds to the same receptor as a liver X receptor agonist, but which induces a pharmacological response opposite to that agonist.
substance with liver X receptor inverse agonist role
A substance that binds to the same receptor binding-site as an agonist for that receptor, but which exerts the opposite pharmacological effect.
An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of thymidine phosphorylase (EC 2.4.2.4).
EC 2.4.2.4 (thymidine phosphorylase) inhibitors
pyrimidine deoxynucleoside phosphorylase inhibitor
pyrimidine deoxynucleoside phosphorylase inhibitors
thymidine-orthophosphate deoxyribosyltransferase inhibitor
thymidine-orthophosphate deoxyribosyltransferase inhibitors
thymidine:phosphate deoxy-D-ribosyltransferase inhibitor
thymidine:phosphate deoxy-D-ribosyltransferase inhibitors
thymidine:phosphate deoxy-alpha-D-ribosyltransferase inhibitor
thymidine:phosphate deoxy-alpha-D-ribosyltransferase inhibitors
substance with EC 2.4.2.4 (thymidine phosphorylase) inhibitor role
Any EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor that interferes with the action of any such enzyme using a quinone or similar compound as an acceptor.
EC 1.8.5.* (oxidoreductase acting on sulfur group donors, quinone or similar as acceptor) inhibitors
oxidoreductase acting on sulfur group donors, quinone or similar as acceptor (EC 1.8.5.*) inhibitor
oxidoreductase acting on sulfur group donors, quinone or similar as acceptor (EC 1.8.5.*) inhibitors
substance with EC 1.8.5.* (oxidoreductase acting on sulfur group donors, quinone or similar as acceptor) inhibitor role
An EC 1.8.5.* (oxidoreductase acting on sulfur group donors, quinone or similar as acceptor) inhibitor that interferes with the action of sulfide:quinone reductase (EC 1.8.5.4).
EC 1.8.5.4 (sulfide:quinone reductase) inhibitors
sulfide:quinone oxidoreductase inhibitor
sulfide:quinone oxidoreductase inhibitors
sulfide:quinone reductase (EC 1.8.5.4) inhibitor
sulfide:quinone reductase (EC 1.8.5.4) inhibitors
substance with EC 1.8.5.4 (sulfide:quinone reductase) inhibitor role
An inhibitor that interferes with the dimerisation of extracellular signal-regulated kinase (ERK).
extracellular signal-regulated kinase dimerisation inhibitor
extracellular signal-regulated kinase dimerisation inhibitors
substance with ERK dimerisation inhibitor role
A compound that enhances the activity of a steroid receptor coactivator.
steroid receptor coactivator small molecule stimulator
steroid receptor coactivator small molecule stimulators
steroid receptor coactivator stimulators
substance with steroid receptor coactivator stimulator role
A chemical compound that, when added to a liquid or gas, decreases the corrosion rate of a material, typically a metal or an alloy.
A GABA receptor agonist specific for GABAA receptors, ligand-gated ion channels (also known as ionotropic receptors).
substance with GABAA receptor agonist role
Any inhibitor of erythropoietin, a glycoprotein hormone that controls erythropoiesis (red blood cell production).
substance with erythropoietin inhibitor role
An antagonist at purinergic P2 receptors
substance with purinergic receptor P2 antagonist role
An antagonist at purinergic P2X receptors
substance with purinergic receptor P2X antagonist role
Any compound that inhibits collagen cross-linking.
substance with collagen cross-linking inhibitor role
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of tau-protein kinase inhibitor (EC 2.7.11.26).
ATP:[tau-protein] O-phosphotransferase inhibitor
ATP:[tau-protein] O-phosphotransferase inhibitors
ATP:tau-protein O-phosphotransferase inhibitor
ATP:tau-protein O-phosphotransferase inhibitors
EC 2.7.11.26 (tau-protein kinase) inhibitors
glycogen synthase kinase-3beta inhibitor
glycogen synthase kinase-3beta inhibitors
substance with EC 2.7.11.26 (tau-protein kinase) inhibitor role
An agonist that selectively binds to and activates elastin-laminin receptors.
substance with elastin-laminin receptor agonist role
An EC 1.1.5.* (oxidoreductase acting on donor CH-OH group, quinone or similar compound as acceptor) inhibitor that interferes with the action of glycerol-3-phosphate dehydrogenase (EC 1.1.5.3).
EC 1.1.5.3 (glycerol-3-phosphate dehydrogenase) inhibitors
glycerol-3-phosphate dehydrogenase inhibitor
glycerol-3-phosphate dehydrogenase inhibitors
substance with EC 1.1.5.3 (glycerol-3-phosphate dehydrogenase) inhibitor role
An EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor that interferes with the action of any such enzyme using a quinone or similar compound as acceptor (EC 1.1.5.*).
EC 1.1.5.* (oxidoreductase acting on donor CH-OH group, quinone or simliar compound as acceptor) inhibitors
oxidoreductase acting on donor CH-OH group, quinone or simliar compound as acceptor (EC 1.1.5.*) inhibitor
oxidoreductase acting on donor CH-OH group, quinone or simliar compound as acceptor (EC 1.1.5.*) inhibitors
substance with EC 1.1.5.* (oxidoreductase acting on donor CH-OH group, quinone or similar compound as acceptor) inhibitor role
Any activator of vascular endothelial growth factor (VEGF).
vascular endothelial growth factor activator
vascular endothelial growth factor activators
vascular endothelial growth factor inducer
vascular endothelial growth factor inducers
An antagonist that binds to and deactivates lysophosphatidic acid receptors.
lysophosphatidic acid receptor antagonists
substance with lysophosphatidic acid receptor antagonist role
An antagonist that binds to and deactivates TGFbeta receptors.
transforming growth factor receptor antagonist
transforming growth factor receptor antagonists
substance with TGFbeta receptor antagonist role
Any inhibitor of macrophage migration inhibitory factor (MIF).
macrophage migration inhibitory factor inhibitors
substance with macrophage migration inhibitory factor inhibitor role