# GORULE violations assigned by ParkinsonsUK-UCL

## SUMMARY

This report generated on 2024-10-22

## Contents

[gorule-0000008](#gorule-0000008)[No annotations should be made to uninformative high level terms]{}

[gorule-0000020](#gorule-0000020)[Automatic repair of annotations to merged or obsoleted terms]{}

[gorule-0000046](#gorule-0000046)[The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.]{}

## MESSAGES

###gorule-0000008

No annotations should be made to uninformative high level terms

* total: 6
#### Messages
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI	MGI:98958	Wnt5a	involved_in	GO:0032092	PMID:23109420	IDA		P	Protein Wnt-5a		protein	taxon:10090	20170410	ParkinsonsUK-UCL	has_input(UniProtKB:Q13009),part_of(GO:0016055),occurs_in(CL:0000700)|has_input(UniProtKB:Q92997),part_of(GO:0016055),occurs_in(CL:0000700)	
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI	MGI:99441	Ckmt1	involved_in	GO:0032091	PMID:21370995	IDA		P	Creatine kinase U-type, mitochondrial		protein	taxon:10090	20140728	ParkinsonsUK-UCL	has_input(UniProtKB:P21796),has_input(UniProtKB:P12236)	
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI	MGI:1914740	Ufl1	involved_in	GO:0032092	PMID:21494687	TAS		P	E3 UFM1-protein ligase 1		protein	taxon:10090	20161103	ParkinsonsUK-UCL	has_input(UniProtKB:P61961),has_input(UniProtKB:Q80WW9)	
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI	MGI:1920431	Nfatc4	involved_in	GO:0032091	PMID:21880741	IDA		P	Nuclear factor of activated T-cells, cytoplasmic 4		protein	taxon:10090	20151214	ParkinsonsUK-UCL	has_input(UniProtKB:P51141),has_input(UniProtKB:Q02248),part_of(GO:0030178)	
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI	MGI:1920431	Nfatc4	involved_in	GO:0032091	PMID:21880741	IDA		P	Nuclear factor of activated T-cells, cytoplasmic 4		protein	taxon:10090	20170410	ParkinsonsUK-UCL	has_input(UniProtKB:Q61062),occurs_in(GO:0005634),part_of(GO:0030178)|has_input(UniProtKB:Q02248),occurs_in(GO:0005634),part_of(GO:0030178)	
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI	MGI:1891731	Stub1	involved_in	GO:0032091	PMID:12150907	IDA		P	E3 ubiquitin-protein ligase CHIP		protein	taxon:10090	20140813	ParkinsonsUK-UCL	part_of(GO:0031398)	
`

###gorule-0000020

Automatic repair of annotations to merged or obsoleted terms

* total: 10
#### Messages
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI	MGI:98953	Wnt1	enables	GO:0048018	PMID:21752258	IC	GO:1903204	F	Proto-oncogene Wnt-1		protein	taxon:10090	20160914	ParkinsonsUK-UCL	has_input(UniProtKB:O70421),part_of(GO:0060070)	
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI	MGI:98953	Wnt1	involved_in	GO:0036520	PMID:21752258	IMP		P	Proto-oncogene Wnt-1		protein	taxon:10090	20190918	ParkinsonsUK-UCL	occurs_in(UBERON:0001891),causally_upstream_of(GO:1903204)	
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI	MGI:1355296	Prkn	involved_in	GO:0032436	PMID:23858059	IMP		P	E3 ubiquitin-protein ligase parkin		protein	taxon:10090	20140729	ParkinsonsUK-UCL	has_input(UniProtKB:Q8VBV4),part_of(GO:1903204),occurs_in(CL:0000530),occurs_in(UBERON:0000955)	
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`MGI	MGI:1270126	Ulk1	enables	GO:0004674	PMID:21855797	IMP		F	Serine/threonine-protein kinase ULK1		protein	taxon:10090	20160229	ParkinsonsUK-UCL	has_input(UniProtKB:Q91YI1),causally_upstream_of(GO:0098779)	
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`MGI	MGI:109531	Cdc37	involved_in	GO:0098779	PMID:21855797	IDA		P	Hsp90 co-chaperone Cdc37		protein	taxon:10090	20150216	ParkinsonsUK-UCL		
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`MGI	MGI:1333752	Hdac6	involved_in	GO:0098779	PMID:20457763	IGI	UniProtKB:Q9JK66	P	Histone deacetylase 6		protein	taxon:10090	20150603	ParkinsonsUK-UCL		
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`MGI	MGI:1928676	Htra2	enables	GO:0008233	PMID:24709290	IMP		F	Serine protease HTRA2, mitochondrial		protein	taxon:10090	20161102	ParkinsonsUK-UCL	has_input(UniProtKB:Q8VCM5),part_of(GO:0034599)|has_input(UniProtKB:Q8VCM5),part_of(GO:1904924)	
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`MGI	MGI:1928676	Htra2	involved_in	GO:0006508	PMID:24709290	IMP		P	Serine protease HTRA2, mitochondrial		protein	taxon:10090	20161102	ParkinsonsUK-UCL	has_input(UniProtKB:Q8VCM5),part_of(GO:0034599)|has_input(UniProtKB:Q8VCM5),part_of(GO:1904924)	
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`MGI	MGI:1928676	Htra2	involved_in	GO:1904924	PMID:24709290	IMP		P	Serine protease HTRA2, mitochondrial		protein	taxon:10090	20161102	ParkinsonsUK-UCL		
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`MGI	MGI:1915600	Mul1	involved_in	GO:1904925	PMID:24709290	IMP		P	Mitochondrial ubiquitin ligase activator of NFKB 1		protein	taxon:10090	20161102	ParkinsonsUK-UCL		
`

###gorule-0000046

The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

* total: 4
#### Messages
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:1921256	Dnm1l	enables	GO:0042803	PMID:20585624	IPI	UniProtKB:Q8K1M6	F	Dynamin-1-like protein		protein	taxon:10090	20230309	ParkinsonsUK-UCL		
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:1352504	Hip1r	enables	GO:0042803	PMID:11564758	IPI	UniProtKB:Q9JKY5	F	Huntingtin-interacting protein 1-related protein		protein	taxon:10090	20230309	ParkinsonsUK-UCL		
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:1352504	Hip1r	enables	GO:0042803	PMID:15533940	IPI	UniProtKB:Q9JKY5	F	Huntingtin-interacting protein 1-related protein		protein	taxon:10090	20230309	ParkinsonsUK-UCL		
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:1352504	Hip1r	enables	GO:0042803	PMID:18790740	IPI	UniProtKB:Q9JKY5	F	Huntingtin-interacting protein 1-related protein		protein	taxon:10090	20230309	ParkinsonsUK-UCL		
`