format-version: 1.2
data-version: go/2024-09-26/subsets/goslim_virus.owl
subsetdef: chebi_ph7_3 "Rhea list of ChEBI terms representing the major species at pH 7.3."
subsetdef: gocheck_do_not_annotate "Term not to be used for direct annotation"
subsetdef: gocheck_obsoletion_candidate "Terms planned for obsoletion"
subsetdef: goslim_agr "AGR slim"
subsetdef: goslim_aspergillus "Aspergillus GO slim"
subsetdef: goslim_candida "Candida GO slim"
subsetdef: goslim_chembl "ChEMBL protein targets summary"
subsetdef: goslim_drosophila "Drosophila GO slim"
subsetdef: goslim_euk_cellular_processes_ribbon "GO ribbon for eukaroytic cellular processes"
subsetdef: goslim_flybase_ribbon "Insecta GO ribbon slim"
subsetdef: goslim_generic "Generic GO slim"
subsetdef: goslim_metagenomics "Metagenomics GO slim"
subsetdef: goslim_mouse "Mouse GO slim"
subsetdef: goslim_pir "PIR GO slim"
subsetdef: goslim_plant "Plant GO slim"
subsetdef: goslim_plant_ribbon "Plant GO ribbon"
subsetdef: goslim_pombe "Fission yeast GO slim"
subsetdef: goslim_prokaryote "GO subset for prokaryotes"
subsetdef: goslim_prokaryote_ribbon "Prokaryote GO ribbon slim"
subsetdef: goslim_synapse "synapse GO slim"
subsetdef: goslim_virus "GO subset for viruses"
subsetdef: goslim_yeast "Yeast GO slim"
synonymtypedef: syngo_official_label "label approved by the SynGO project"
synonymtypedef: systematic_synonym "Systematic synonym" EXACT
ontology: go/subsets/goslim_virus
property_value: owl:versionInfo "2024-09-26" xsd:string

[Term]
id: GO:0001907
name: symbiont-mediated killing of host cell
namespace: biological_process
def: "A process mediated by a symbiont that results in the death of a cell in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:add, PMID:11123917, PMID:22992735, PMID:23230295, PMID:26633512]
subset: goslim_virus
synonym: "killing by symbiont of host cells" EXACT []
synonym: "pathogenesis" RELATED []
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27342" xsd:anyURI

[Term]
id: GO:0016032
name: viral process
namespace: biological_process
alt_id: GO:0022415
def: "A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle." [GOC:bf, GOC:jl, GOC:mah]
comment: See also the biological process terms 'viral infectious cycle ; GO:0019058' and 'lysogeny ; GO:0030069'.
subset: goslim_metagenomics
subset: goslim_pir
subset: goslim_virus
synonym: "viral infection" RELATED []
synonym: "virulence" RELATED []
synonym: "virus process" EXACT [GOC:bf, GOC:jl]
xref: Wikipedia:Viral_life_cycle

[Term]
id: GO:0019028
name: viral capsid
namespace: cellular_component
alt_id: GO:0046728
def: "The protein coat that surrounds the infective nucleic acid in some virus particles. It comprises numerous regularly arranged subunits, or capsomeres." [GOC:mtg_sensu, ISBN:0198506732]
subset: goslim_chembl
subset: goslim_virus
xref: Wikipedia:Capsid

[Term]
id: GO:0019048
name: modulation by virus of host process
namespace: biological_process
alt_id: GO:0044661
alt_id: GO:0044792
def: "The process in which a virus effects a change in the structure or processes of its host organism." [GOC:bf, GOC:jl, ISBN:0781718325, UniProtKB-KW:KW-0945]
subset: goslim_virus
synonym: "disruption by virus of host cell" RELATED []
synonym: "host-virus interaction" EXACT [GOC:bf, GOC:jl]
synonym: "modulation by virus of host anatomical structure or process" RELATED [GOC:bf, GOC:jl]
synonym: "modulation by virus of host anatomy or process" EXACT [GOC:bf, GOC:jl]
synonym: "modulation by virus of host morphology or physiology" RELATED []
synonym: "viral interaction with host" EXACT []
synonym: "viral-host process" EXACT [GOC:bf, GOC:jl]
synonym: "virus-host interaction" BROAD [GOC:bf, GOC:jl]
synonym: "virus-host process" EXACT [GOC:bf, GOC:jl]
xref: VZ:886 "Vertebrate host-virus interactions"
is_a: GO:0016032 ! viral process
is_a: GO:0044003 ! symbiont-mediated perturbation of host process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18605" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18719" xsd:anyURI
created_by: jl
creation_date: 2012-08-01T13:41:00Z

[Term]
id: GO:0019049
name: virus-mediated perturbation of host defense response
namespace: biological_process
alt_id: GO:0019052
alt_id: GO:0019053
alt_id: GO:0030683
alt_id: GO:0050690
def: "A process in which a virus interferes with the ability of the host to mount a defense in response to its presence. Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction." [ISBN:1555811272]
subset: goslim_virus
synonym: "evasion of host defenses by virus" NARROW []
synonym: "mitigation of host antiviral defense response" NARROW []
synonym: "mitigation of host defenses by virus" EXACT []
synonym: "perturbation of host defense response by virus" EXACT []
synonym: "regulation by virus of antiviral response" NARROW []
synonym: "regulation of defense response to virus by virus" EXACT []
synonym: "viral host defence evasion" NARROW []
synonym: "viral host defense evasion" NARROW []
synonym: "viral regulation of antiviral response" EXACT []
is_a: GO:0019048 ! modulation by virus of host process
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23043" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25016" xsd:anyURI

[Term]
id: GO:0019058
name: viral life cycle
namespace: biological_process
alt_id: GO:0019067
def: "A set of processes which all viruses follow to ensure survival; includes attachment and entry of the virus particle, decoding of genome information, translation of viral mRNA by host ribosomes, genome replication, and assembly and release of viral particles containing the genome." [ISBN:1555811272]
subset: goslim_virus
synonym: "lytic viral life cycle" RELATED []
synonym: "viral assembly, maturation, egress, and release" NARROW [GOC:bf, GOC:jl]
synonym: "viral infectious cycle" RELATED [GOC:bf, GOC:jl]
synonym: "viral replication" RELATED [GOC:bf, GOC:jl]
is_a: GO:0016032 ! viral process

[Term]
id: GO:0019062
name: virion attachment to host cell
namespace: biological_process
def: "The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection." [GOC:bf, GOC:jl, UniProtKB-KW:KW-1161, VZ:956]
subset: goslim_virus
synonym: "viral absorption" EXACT []
synonym: "viral attachment to host cell" RELATED [GOC:bf, GOC:jl]
synonym: "virion attachment to host cell surface receptor" NARROW []
xref: VZ:956 "Viral attachment to host cell"
relationship: part_of GO:0019058 ! viral life cycle

[Term]
id: GO:0019068
name: virion assembly
namespace: biological_process
alt_id: GO:0042963
def: "A late phase of the viral life cycle during which all the components necessary for the formation of a mature virion collect at a particular site in the cell and the basic structure of the virus particle is formed." [ISBN:0121585336]
subset: goslim_virus
synonym: "bacteriophage assembly" NARROW [GOC:bm]
synonym: "phage assembly" NARROW [GOC:bm]
synonym: "viral assembly" EXACT []
synonym: "viral particle assembly" EXACT []
synonym: "virion assembly and maintenance" EXACT [GOC:bf, GOC:jl]
synonym: "virion organization" EXACT [GOC:bf, GOC:jl]
synonym: "virus assembly" EXACT [GOC:dph, GOC:tb]
synonym: "virus particle assembly" EXACT []
is_a: GO:0016032 ! viral process
relationship: part_of GO:0019058 ! viral life cycle

[Term]
id: GO:0019072
name: viral genome packaging
namespace: biological_process
def: "The encapsulation of the viral genome within the capsid." [ISBN:0121585336]
subset: goslim_virus
is_a: GO:0016032 ! viral process
relationship: part_of GO:0019068 ! virion assembly

[Term]
id: GO:0019080
name: viral gene expression
namespace: biological_process
def: "A process by which a viral gene is converted into a mature gene product or products (proteins or RNA). This includes viral transcription, processing to produce a mature RNA product, and viral translation." [GOC:bf, GOC:jl, ISBN:0121585336]
subset: goslim_virus
synonym: "viral genome expression" EXACT [GOC:jl]
is_a: GO:0016032 ! viral process

[Term]
id: GO:0019083
name: viral transcription
namespace: biological_process
def: "The process by which a viral genome, or part of a viral genome, is transcribed within the host cell." [GOC:jl, ISBN:0781702534]
subset: goslim_virus
is_a: GO:0016032 ! viral process
relationship: part_of GO:0019080 ! viral gene expression

[Term]
id: GO:0020002
name: host cell plasma membrane
namespace: cellular_component
def: "The plasma membrane surrounding a host cell." [GOC:mb]
subset: goslim_virus

[Term]
id: GO:0020003
name: symbiont-containing vacuole
namespace: cellular_component
def: "Membrane-bounded vacuole within a host cell in which a symbiont organism resides. The vacuole membrane is derived from both the host and symbiont." [GOC:jl, GOC:mb]
comment: Note that this term does not have a relationship to 'vacuole ; GO:0005773' because it does not fit the definition of a vacuole; the parasitophorous vacuole was so named because it resembles a vacuole in the microscope.
subset: goslim_virus
synonym: "bacterium-containing vacuole" NARROW [PMID:22042847]
synonym: "parasitophorous vacuole" EXACT []
synonym: "pathogen-occupied vacuole" NARROW [PMID:24034612]
synonym: "Salmonella-containing vacuole" NARROW [PMID:10449405, PMID:15121880]
synonym: "SCV" EXACT [PMID:10449405, PMID:15121880]

[Term]
id: GO:0035891
name: exit from host cell
namespace: biological_process
alt_id: GO:0035890
def: "The movement of an organism out of a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:bf, GOC:rs, PMID:19325115]
subset: goslim_virus
synonym: "ejection from host" RELATED [GOC:bf]
synonym: "ejection from host cell" RELATED [PMID:19325115]
synonym: "exit from host" RELATED []
synonym: "host cell exit" EXACT [PMID:19325115]
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23085" xsd:anyURI
created_by: bf
creation_date: 2011-06-15T02:08:03Z

[Term]
id: GO:0039693
name: viral DNA genome replication
namespace: biological_process
alt_id: GO:0039681
def: "The replication of a viral DNA genome." [GOC:bf, GOC:jl, VZ:915]
subset: goslim_virus
synonym: "DNA-dependent viral DNA replication" EXACT [GOC:bf, GOC:jl]
synonym: "viral DNA replication" EXACT [GOC:bf, GOC:jl]
synonym: "viral DNA-dependent DNA replication" EXACT []
is_a: GO:0016032 ! viral process
relationship: part_of GO:0019058 ! viral life cycle
created_by: bf
creation_date: 2013-10-23T15:22:31Z

[Term]
id: GO:0042025
name: host cell nucleus
namespace: cellular_component
alt_id: GO:0033649
def: "A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pamgo_curators]
subset: goslim_virus

[Term]
id: GO:0044003
name: symbiont-mediated perturbation of host process
namespace: biological_process
alt_id: GO:0044004
alt_id: GO:0044055
alt_id: GO:0052065
alt_id: GO:0052251
alt_id: GO:0052265
alt_id: GO:0052389
alt_id: GO:0052509
alt_id: GO:0052510
def: "A process in which a symbiont alters or subverts a biological process in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:cc]
subset: goslim_virus
synonym: "disruption by symbiont of host cell" RELATED []
synonym: "modification by symbiont of host biological process" RELATED []
synonym: "modification by symbiont of host morphology or physiology" RELATED []
synonym: "modulation by symbiont of host system process" NARROW []
synonym: "pathogenesis" RELATED []
synonym: "regulation by symbiont of host system process" NARROW []
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18719" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23089" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28791" xsd:anyURI

[Term]
id: GO:0044161
name: host cell cytoplasmic vesicle
namespace: cellular_component
def: "A vesicle formed of membrane or protein, found in the cytoplasm of a host cell." [GOC:rph]
subset: goslim_virus
created_by: jl
creation_date: 2009-08-11T04:22:21Z

[Term]
id: GO:0044165
name: host cell endoplasmic reticulum
namespace: cellular_component
def: "The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached)." [GOC:jl]
subset: goslim_virus
synonym: "host endoplasmic reticulum" EXACT []
created_by: jl
creation_date: 2009-09-04T11:08:09Z

[Term]
id: GO:0044177
name: host cell Golgi apparatus
namespace: cellular_component
def: "A compound membranous cytoplasmic organelle of eukaryotic host cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack." [GOC:jl]
subset: goslim_virus
synonym: "host Golgi apparatus" EXACT []
created_by: jl
creation_date: 2009-09-04T03:14:38Z

[Term]
id: GO:0044409
name: symbiont entry into host
namespace: biological_process
alt_id: GO:0030260
alt_id: GO:0044411
alt_id: GO:0051806
alt_id: GO:0051828
alt_id: GO:0051830
alt_id: GO:0075052
alt_id: GO:0085027
alt_id: GO:0085028
def: "Entry of a symbiont into the body, tissues, or cells of a host organism as part of the symbiont life cycle. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:vw]
subset: goslim_virus
synonym: "entry into cell of other organism during symbiotic interaction" NARROW [GOC:tb]
synonym: "entry into cell of other organism involved in symbiotic interaction" RELATED []
synonym: "entry into host" EXACT []
synonym: "entry into host cell via penetration peg" NARROW []
synonym: "entry into host through host barriers" RELATED []
synonym: "entry into host via a specialized structure during symbiotic interaction" NARROW []
synonym: "entry into host via enzymatic degradation of host anatomical structure" NARROW []
synonym: "entry into host via enzymatic degradation of host cuticle" NARROW []
synonym: "entry into other organism during symbiotic interaction" RELATED [GOC:tb]
synonym: "entry into other organism involved in symbiotic interaction" RELATED []
synonym: "host invasion" EXACT []
synonym: "host penetration" EXACT [GOC:vw]
synonym: "invasion into host" EXACT []
synonym: "invasion into other organism" RELATED []
synonym: "invasion of host" EXACT []
synonym: "invasion of other organism" RELATED []
synonym: "invasive growth" RELATED []
synonym: "other organism invasion" RELATED []
synonym: "penetration into host" EXACT [GOC:vw]
synonym: "penetration into host via a specialized structure" NARROW [GOC:vw]
synonym: "penetration into host via a specialized structure during symbiotic interaction" NARROW [GOC:vw]
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18563" xsd:anyURI

[Term]
id: GO:0052008
name: symbiont-mediated disruption of host cellular anatomical structure
namespace: biological_process
def: "The process in which an organism effects a change that impairs the structure or function of a host cellular anatomical structure. The host is defined as the larger of the organisms involved in a symbiotic interaction." [ISBN:0198547684]
subset: goslim_virus
synonym: "catabolism of host cellular component by organism" EXACT []
synonym: "catabolism of host structural constituent by organism" EXACT []
synonym: "cytopathogenic effect" RELATED []
synonym: "degradation of host cellular component by organism" EXACT []
synonym: "disassembly by organism of host cellular component" EXACT []
synonym: "disassembly by symbiont of host cellular component" RELATED []
synonym: "disruption by symbiont of host cellular component" EXACT []
synonym: "symbiont-mediated disruption of host cellular anatomical entity" EXACT []
synonym: "symbiont-mediated disruption of host cellular component" BROAD []
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/24127" xsd:anyURI

[Term]
id: GO:0075528
name: perturbation by virus of host immune response
namespace: biological_process
def: "A process in which a virus effects a change in the host immune response." [GOC:bf, GOC:jl]
subset: goslim_virus
synonym: "regulation by virus of host immune system process" EXACT [GOC:jl]
is_a: GO:0019049 ! virus-mediated perturbation of host defense response
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25569" xsd:anyURI
created_by: jl
creation_date: 2011-08-04T02:47:57Z

[Typedef]
id: ends_during
name: ends during
namespace: external
xref: RO:0002093

[Typedef]
id: happens_during
name: happens during
namespace: external
xref: RO:0002092
is_transitive: true
is_a: ends_during ! ends during

[Typedef]
id: has_ontology_root_term
name: has ontology root term
namespace: external
xref: IAO:0000700
is_metadata_tag: true
is_class_level: true

[Typedef]
id: has_part
name: has part
namespace: external
xref: BFO:0000051
is_transitive: true

[Typedef]
id: negatively_regulates
name: negatively regulates
namespace: external
xref: RO:0002212
is_a: regulates ! regulates

[Typedef]
id: occurs_in
name: occurs in
namespace: external
xref: BFO:0000066
transitive_over: part_of ! part of

[Typedef]
id: part_of
name: part of
namespace: external
xref: BFO:0000050
is_transitive: true
inverse_of: has_part ! has part

[Typedef]
id: positively_regulates
name: positively regulates
namespace: external
xref: RO:0002213
holds_over_chain: negatively_regulates negatively_regulates
is_a: regulates ! regulates

[Typedef]
id: regulates
name: regulates
namespace: external
xref: RO:0002211
is_transitive: true

[Typedef]
id: starts_during
name: starts during
namespace: external
xref: RO:0002091

[Typedef]
id: term_tracker_item
name: term tracker item
namespace: external
xref: IAO:0000233
is_metadata_tag: true
is_class_level: true