BFO_0000050
type: ObjectProperty
has db xref: BFO:0000050

BFO_0000051
type: ObjectProperty
has db xref: BFO:0000051

has_not_completed
type: ObjectProperty
has db xref: CL:4030044
shorthand: has_not_completed

lacks_part
type: ObjectProperty
has db xref: CL:4030045
shorthand: lacks_part

lacks_plasma_membrane_part
type: ObjectProperty
has db xref: CL:4030046
shorthand: lacks_plasma_membrane_part

RO_0000053
type: ObjectProperty
has db xref: RO:0000053

RO_0000056
type: ObjectProperty
has db xref: RO:0000056

RO_0001025
type: ObjectProperty
has db xref: RO:0001025

RO_0002100
type: ObjectProperty
has db xref: RO:0002100

RO_0002102
type: ObjectProperty
has db xref: RO:0002102

RO_0002103
type: ObjectProperty
has db xref: RO:0002103

RO_0002104
type: ObjectProperty
has db xref: RO:0002104

RO_0002120
type: ObjectProperty
has db xref: RO:0002120

RO_0002160
type: ObjectProperty
has db xref: RO:0002160

RO_0002162
type: ObjectProperty
has db xref: RO:0002162

RO_0002202
type: ObjectProperty
has db xref: RO:0002202

RO_0002203
type: ObjectProperty
has db xref: RO:0002203

RO_0002207
type: ObjectProperty
has db xref: RO:0002207

RO_0002210
type: ObjectProperty
has db xref: RO:0002210

RO_0002215
type: ObjectProperty
has db xref: RO:0002215

RO_0002216
type: ObjectProperty
has db xref: RO:0002216

RO_0002220
type: ObjectProperty
has db xref: RO:0002220

RO_0002292
type: ObjectProperty
has db xref: RO:0002292

RO_0002339
type: ObjectProperty
has db xref: RO:0002339

RO_0002353
type: ObjectProperty
has db xref: RO:0002353

RO_0003000
type: ObjectProperty
has db xref: RO:0003000

RO_0015015
type: ObjectProperty
has db xref: RO:0015015

RO_0015016
type: ObjectProperty
has db xref: RO:0015016

cell
type: Class
subclass of: UBERON_0000061
subclass of: Restriction
  on property: RO_0002160
  some values from: NCBITaxon_131567
IAO_0000115: A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.

neural crest derived fibroblast
type: Class
equivalent class: Class
  intersection of: fibroblast
  intersection of: Restriction
    on property: RO_0002202
    some values from: migratory neural crest cell
subclass of: fibroblast
subclass of: Restriction
  on property: RO_0002202
  some values from: migratory cranial neural crest cell
IAO_0000115: Any fibroblast that is derived from the neural crest.
has exact synonym: fibroblast neural crest derived

neuronal receptor cell
type: Class
equivalent class: Class
  intersection of: sensory receptor cell
  intersection of: neuron
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0050906
subclass of: sensory neuron
subclass of: sensory receptor cell
IAO_0000115: Any sensory receptor cell that is a(n) neuron and is capable of some detection of stimulus involved in sensory perception.
has exact synonym: neuronal receptor cell (sensu Animalia)

early embryonic cell (metazoa)
type: Class
subclass of: embryonic cell (metazoa)
IAO_0000115: A cell found in the embryo before the formation of all the gem layers is complete.

migratory cranial neural crest cell
type: Class
subclass of: migratory neural crest cell
IAO_0000115: Cell that is part of the migratory cranial neural crest population. Migratory cranial neural crest cells develop from premigratory cranial neural crest cells and have undergone epithelial to mesenchymal transition and delamination.

migratory trunk neural crest cell
type: Class
subclass of: migratory neural crest cell
IAO_0000115: Cell that is part of the migratory trunk neural crest population. Migratory trunk neural crest cells develop from premigratory trunk neural crest cells and have undergone epithelial to mesenchymal transition and delamination.

germ line stem cell
type: Class
equivalent class: Class
  intersection of: germ line cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0017145
subclass of: stem cell
subclass of: germ line cell
IAO_0000115: A stem cell that is the precursor of gametes.
has exact synonym: germline stem cell

male germ cell
type: Class
subclass of: germ cell
subclass of: Restriction
  on property: RO_0002216
  some values from: GO_0007283
IAO_0000115: A germ cell that supports male gamete production. In some species, non-germ cells known as Sertoli cells also play a role in spermatogenesis.

male germ line stem cell
type: Class
subclass of: germ line stem cell
subclass of: male germ cell
IAO_0000115: A stem cell that is the precursor of male gametes.

spermatocyte
type: Class
equivalent class: Class
  intersection of: male germ cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0048137
subclass of: BFO_0000002
subclass of: male germ cell
subclass of: Restriction
  on property: RO_0002202
  some values from: spermatogonium
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0048137
IAO_0000115: A male germ cell that develops from spermatogonia. The euploid primary spermatocytes undergo meiosis and give rise to the haploid secondary spermatocytes which in turn give rise to spermatids.

spermatid
type: Class
equivalent class: Class
  intersection of: male germ cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001375
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0001675
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0007288
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0007289
subclass of: BFO_0000002
subclass of: male germ cell
subclass of: haploid cell
subclass of: Restriction
  on property: RO_0002202
  some values from: secondary spermatocyte
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0001675
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0007288
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0007289
IAO_0000115: A male germ cell that develops from the haploid secondary spermatocytes. Without further division, spermatids undergo structural changes and give rise to spermatozoa.
has exact synonym: nematoblast

sperm
type: Class
subclass of: BFO_0000002
subclass of: male gamete
subclass of: Restriction
  on property: RO_0002202
  some values from: spermatid
IAO_0000115: A mature male germ cell that develops from a spermatid.
has exact synonym: sperm cell
has exact synonym: spermatozoid
has exact synonym: spermatozoon

spermatogonium
type: Class
equivalent class: Class
  intersection of: male germ cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001394
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001501
subclass of: male germ cell
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0001394
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0001501
IAO_0000115: An euploid male germ cell of an early stage of spermatogenesis.
has exact synonym: spermatogonial cell

female germ cell
type: Class
equivalent class: Class
  intersection of: germ cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0048477
subclass of: germ cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0048477
IAO_0000115: Female germ cell is a germ cell that supports female gamete production.

female germ line stem cell
type: Class
equivalent class: Class
  intersection of: female germ cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0017145
subclass of: germ line stem cell
subclass of: female germ cell
IAO_0000115: A stem cell that is the precursor of female gametes.

oocyte
type: Class
subclass of: BFO_0000002
subclass of: female germ cell
subclass of: eukaryotic cell
subclass of: Restriction
  on property: RO_0000056
  some values from: GO_0007143
subclass of: Restriction
  on property: RO_0002160
  some values from: NCBITaxon_33208
IAO_0000115: A female germ cell that has entered meiosis.
has related synonym: oogonium

oogonial cell
type: Class
equivalent class: Class
  intersection of: female germ cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0000278
subclass of: BFO_0000002
subclass of: female germ cell
subclass of: Restriction
  on property: RO_0002202
  some values from: primordial germ cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0000278
IAO_0000115: An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes.

egg cell
type: Class
subclass of: BFO_0000002
subclass of: female gamete
subclass of: Restriction
  on property: RO_0000056
  some values from: GO_0007143
subclass of: Restriction
  on property: RO_0002202
  some values from: oocyte
IAO_0000115: A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization.
has exact synonym: mature oocyte
has exact synonym: ovum

invertebrate nurse cell
type: Class
subclass of: BFO_0000002
subclass of: polyploid cell
subclass of: CL_4029002
subclass of: Restriction
  on property: RO_0002202
  some values from: cystoblast
IAO_0000115: A germline cell that contributes to the development of the oocyte by transferring cytoplasm directly to oocyte.
has related synonym: nurse cell

smooth muscle cell neural crest derived
type: Class
equivalent class: Class
  intersection of: smooth muscle cell
  intersection of: Restriction
    on property: RO_0002202
    some values from: migratory neural crest cell
subclass of: smooth muscle cell
subclass of: Restriction
  on property: RO_0002202
  some values from: migratory cranial neural crest cell
IAO_0000115: A smooth muscle cell derived from the neural crest.

neural crest derived neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: RO_0002202
    some values from: migratory neural crest cell
subclass of: BFO_0000002
subclass of: neuron
subclass of: Restriction
  on property: RO_0002202
  some values from: CL_0002676
IAO_0000115: Any neuron that develops from some migratory neural crest cell.
has exact synonym: neuron neural crest derived

glioblast
type: Class
subclass of: BFO_0000002
subclass of: non-terminally differentiated cell
subclass of: Restriction
  on property: RO_0002202
  some values from: neurectodermal cell

neuroblast (sensu Vertebrata)
type: Class
subclass of: non-terminally differentiated cell
subclass of: eukaryotic cell
subclass of: Restriction
  on property: RO_0002160
  some values from: NCBITaxon 7742
IAO_0000115: A cell that will develop into a neuron often after a migration phase.
has exact synonym: neuroblast

stem cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0017145
subclass of: CL_0011115
subclass of: Restriction
  on property: RO_0002162
  some values from: NCBITaxon_33208
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0017145
IAO_0000115: A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
has exact synonym: animal stem cell

single fate stem cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001400
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0017145
subclass of: somatic stem cell
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0001400
IAO_0000115: A stem cell that self-renews as well as give rise to a single mature cell type.
has exact synonym: unipotent stem cell
has exact synonym: unipotential stem cell

epithelial fate stem cell
type: Class
subclass of: single fate stem cell
has exact synonym: epithelial stem cell

hematopoietic stem cell
type: Class
equivalent class: Class
  intersection of: hematopoietic cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002981
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002244
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0048103
subclass of: somatic stem cell
subclass of: CL_0008001
subclass of: CL_0011026
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002981
subclass of: Restriction
  on property: RO_0002202
  some values from: angioblastic mesenchymal cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002244
IAO_0000115: A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119.
has exact synonym: blood forming stem cell
has exact synonym: hemopoietic stem cell
has related synonym: HSC
has related synonym: colony forming unit hematopoietic

erythroid progenitor cell
type: Class
subclass of: erythroid lineage cell
subclass of: myeloid lineage restricted progenitor cell
subclass of: Restriction
  on property: RO_0002202
  some values from: megakaryocyte-erythroid progenitor cell
IAO_0000115: A progenitor cell committed to the erythroid lineage.
has related synonym: BFU-E
has related synonym: CFU-E
has related synonym: blast forming unit erythroid
has related synonym: burst forming unit erythroid
has related synonym: colony forming unit erythroid
has related synonym: erythroid stem cell

germ line cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0022414
IAO_0000115: A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring.

monoblast
type: Class
equivalent class: Class
  intersection of: monopoietic cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: CL_0017503
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0000791
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0005730
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001012
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030224
subclass of: myeloid cell
subclass of: monopoietic cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: CL_0017503
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0000791
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0005730
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001012
subclass of: Restriction
  on property: RO_0002202
  some values from: macrophage dendritic cell progenitor
IAO_0000115: A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus.
has related synonym: CFU-M
has related synonym: colony forming unit macrophage
has related synonym: colony forming unit monocyte
has related synonym: monocyte stem cell

neutrophilic myeloblast
type: Class
equivalent class: Class
  intersection of: myeloblast
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000001944
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000005307
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000007857
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000010799
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000014362
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030223
subclass of: neutrophil progenitor cell
subclass of: myeloblast
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000001944
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000005307
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000007857
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000010799
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000014362
subclass of: Restriction
  on property: RO_0002202
  some values from: neutrophil progenitor cell
IAO_0000115: A myeloblast committed to the neutrophil lineage. This cell type is GATA-1 positive, C/EBPa-positive, AML-1-positive, c-myb-positive and has low expression of PU.1 transcription factor.
has related synonym: neutrophilic granuloblast

mature basophil
type: Class
equivalent class: Class
  intersection of: basophil
  intersection of: Restriction
    on property: BFO_0000051
    some values from: Class
      intersection of: GO_0005634
      intersection of: Restriction
        on property: RO_0000053
        some values from: PATO_0001979
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002349
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002351
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002830
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0008015
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032616
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032633
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0048295
subclass of: basophil
subclass of: histamine secreting cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: GO_0005634
    intersection of: Restriction
      on property: RO_0000053
      some values from: PATO_0001979
subclass of: Restriction
  on property: RO_0002202
  some values from: band form basophil
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002349
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002351
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002830
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032616
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032633
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0048295
IAO_0000115: A fully differentiated basophil, a granular leukocyte with an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation.
has broad synonym: polymorphonuclear leucocyte
has broad synonym: polymorphonuclear leukocyte
has exact synonym: mature basophil leucocyte
has exact synonym: mature basophil leukocyte

neural stem cell
type: Class
subclass of: BFO_0000002
subclass of: neural cell
subclass of: Restriction
  on property: RO_0002202
  some values from: neurectodermal cell
IAO_0000115: An undifferentiated neural cell that originates from the neuroectoderm and has the capacity both to perpetually self-renew without differentiating and to generate multiple central nervous system neuronal and glial cell types.
has exact synonym: NSC
has exact synonym: neuronal stem cell

multi fate stem cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001402
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0017145
subclass of: stem cell
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0001402
IAO_0000115: A stem cell that can give rise to multiple lineages of cells.
has exact synonym: multi-fate stem cell
has exact synonym: multifate stem cell
has exact synonym: multipotent cell
has exact synonym: multipotent stem cell

common myeloid progenitor
type: Class
subclass of: hematopoietic oligopotent progenitor cell
disjoint with: megakaryocyte-erythroid progenitor cell
disjoint with: common lymphoid progenitor
disjoint with: granulocyte monocyte progenitor cell
IAO_0000115: A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages.
has exact synonym: common myeloid precursor
has related synonym: CFU-GEMM
has related synonym: CFU-S
has related synonym: CMP
has related synonym: colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte
has related synonym: multipotential myeloid stem cell
has related synonym: myeloid stem cell
has related synonym: pluripotent stem cell (bone marrow)

megakaryocyte-erythroid progenitor cell
type: Class
equivalent class: Class
  intersection of: hematopoietic oligopotent progenitor cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030218
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030219
subclass of: myeloid cell
subclass of: hematopoietic oligopotent progenitor cell
subclass of: CL_0011026
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030218
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030219
disjoint with: granulocyte monocyte progenitor cell
disjoint with: macrophage dendritic cell progenitor
IAO_0000115: A progenitor cell committed to the megakaryocyte and erythroid lineages.
has exact synonym: CFU-EM
has exact synonym: CFU-MegE
has exact synonym: MEP
has exact synonym: Meg/E progenitor
has exact synonym: colony forming unit erythroid megakaryocyte
has exact synonym: megakaryocyte/erythrocyte progenitor
has exact synonym: megakaryocyte/erythroid progenitor cell

common lymphoid progenitor
type: Class
equivalent class: Class
  intersection of: hematopoietic oligopotent progenitor cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030098
subclass of: hematopoietic oligopotent progenitor cell
subclass of: CL_0011026
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030098
IAO_0000115: A oligopotent progenitor cell committed to the lymphoid lineage.
has exact synonym: common lymphocyte precursor
has exact synonym: common lymphocyte progenitor
has exact synonym: common lymphoid precursor
has related synonym: CLP
has related synonym: ELP
has related synonym: committed lymphopoietic stem cell
has related synonym: early lymphocyte progenitor
has related synonym: lymphoid stem cell
has related synonym: lymphopoietic stem cell

non-terminally differentiated cell
type: Class
subclass of: CL_0011115
IAO_0000115: A precursor cell with a limited number of potential fates.
has exact synonym: blast cell

myoblast
type: Class
subclass of: muscle precursor cell
IAO_0000115: A cell that is commited to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair.

fibroblast
type: Class
subclass of: BFO_0000002
subclass of: connective tissue cell
subclass of: Restriction
  on property: RO_0002202
  some values from: mesenchymal stem cell
IAO_0000115: A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.

chondroblast
type: Class
subclass of: BFO_0000002
subclass of: non-terminally differentiated cell
subclass of: connective tissue cell
subclass of: Restriction
  on property: RO_0002202
  some values from: CL_0007009
subclass of: Restriction
  on property: RO_0003000
  some values from: UBERON_0002418
IAO_0000115: Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell.
has exact synonym: chrondoplast

ameloblast
type: Class
subclass of: simple columnar epithelial cell
subclass of: secretory cell
subclass of: ecto-epithelial cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0005176
subclass of: Restriction
  on property: RO_0002202
  some values from: CL_0007000
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0097186
subclass of: Restriction
  on property: RO_0002220
  some values from: UBERON_0001763
subclass of: Restriction
  on property: RO_0003000
  some values from: UBERON_0001752
IAO_0000115: Skeletogenic cell that produces enamel, overlies the odontogenic papilla, and arises from the differentiation of a preameloblast cell.
has exact synonym: amelocyte
has exact synonym: enamel secreting cell

odontoblast
type: Class
subclass of: non-terminally differentiated cell
subclass of: neurecto-epithelial cell
subclass of: dental pulp cell
subclass of: CL_0011026
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0005176
subclass of: Restriction
  on property: RO_0002202
  some values from: CL_0007003
subclass of: Restriction
  on property: RO_0003000
  some values from: UBERON_0001751
IAO_0000115: Skeletogenic cell that secretes dentine matrix, is derived from the odontogenic papilla, and develops from a preodontoblast cell.

osteoblast
type: Class
subclass of: non-terminally differentiated cell
subclass of: connective tissue cell
subclass of: CL_0011026
subclass of: Restriction
  on property: RO_0002202
  some values from: CL_0007010
subclass of: Restriction
  on property: RO_0003000
  some values from: UBERON_0008883
IAO_0000115: Skeletogenic cell that secretes osteoid, is capable of producing mineralized (hydroxyapatite) matrix, is located adjacent to or within osteoid tissue, and arises from the transformation of a preosteoblast cell.

ciliated cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0005929
subclass of: cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0005929
IAO_0000115: A cell that has a filiform extrusion of the cell surface.

epithelial cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000483
disjoint with: leukocyte
IAO_0000115: A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.
has exact synonym: epitheliocyte

ciliated epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0005929
subclass of: ciliated cell
subclass of: epithelial cell
IAO_0000115: An epithelial cell that has a cilia.

duct epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000058
subclass of: epithelial cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000058
IAO_0000115: An epithelial cell that is part of a duct.

branched duct epithelial cell
type: Class
subclass of: duct epithelial cell

blood vessel endothelial cell
type: Class
equivalent class: Class
  intersection of: endothelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001981
subclass of: endothelial cell of vascular tree
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0004638
subclass of: Restriction
  on property: RO_0002202
  some values from: CL_0002546
IAO_0000115: An endothelial cell that lines the vasculature.

non-branched duct epithelial cell
type: Class
subclass of: duct epithelial cell
subclass of: meso-epithelial cell

columnar/cuboidal epithelial cell
type: Class
subclass of: epithelial cell
IAO_0000115: A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.

squamous epithelial cell
type: Class
subclass of: epithelial cell

mesothelial cell
type: Class
subclass of: squamous epithelial cell
subclass of: lining cell
subclass of: meso-epithelial cell
IAO_0000115: A flattened epithelial cell of mesenchymal origin that lines the serous cavity.
has exact synonym: mesotheliocyte

stratified epithelial cell
type: Class
subclass of: BFO_0000002
subclass of: epithelial cell
subclass of: Restriction
  on property: RO_0002202
  some values from: stratified epithelial stem cell

blood cell
type: Class
equivalent class: Class
  intersection of: hematopoietic cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0008015
subclass of: hematopoietic cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0008015
IAO_0000115: A cell found predominately in the blood.

epithelial cell of lung
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000115
subclass of: CL_0002632
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000115
IAO_0000115: An epithelial cell of the lung.
has exact synonym: lung epithelial cell

epithelial cell of pancreas
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001264
subclass of: endo-epithelial cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001264
IAO_0000115: An epithelial cell of the pancreas.
has exact synonym: pancreas epithelial cell
has exact synonym: pancreatic epithelial cell

T cell
type: Class
equivalent class: Class
  intersection of: lymphocyte
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002456
subclass of: lymphocyte
subclass of: Restriction
  on property: RO_0002202
  some values from: pro-T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002456
disjoint with: lymphocyte of B lineage
IAO_0000115: A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.
has exact synonym: T lymphocyte
has exact synonym: T-cell
has exact synonym: T-lymphocyte
has related synonym: immature T cell
has related synonym: mature T cell

osteoclast
type: Class
equivalent class: Class
  intersection of: myeloid leukocyte
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001474
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000001850
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000001937
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000001944
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000007597
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000011178
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001954
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002062
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0045453
subclass of: phagocyte (sensu Vertebrata)
subclass of: myeloid leukocyte
subclass of: bone cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000001850
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000001937
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000001944
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000007597
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000011178
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001954
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002062
subclass of: Restriction
  on property: RO_0002202
  some values from: monocyte
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0045453
IAO_0000115: A specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. This cell has the following markers: tartrate-resistant acid phosphatase type 5-positive, PU.1-positive, c-fos-positive, nuclear factor NF-kappa-B p100 subunit-positive, tumor necrosis factor receptor superfamily member 11A-positive and macrophage colony-stimulating factor 1 receptor-positive.
has related synonym: chondroclast

granulocyte
type: Class
equivalent class: Class
  intersection of: myeloid leukocyte
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0030141
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001012
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001332
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001969
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0008015
subclass of: blood cell
subclass of: myeloid leukocyte
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0030141
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001012
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001332
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001969
IAO_0000115: A leukocyte with abundant granules in the cytoplasm.
has exact synonym: granular leucocyte
has exact synonym: granular leukocyte
has exact synonym: polymorphonuclear leukocyte

neuron associated cell
type: Class
subclass of: BFO_0000002
subclass of: neural cell
subclass of: Restriction
  on property: RO_0002202
  some values from: neurectodermal cell

mature neutrophil
type: Class
equivalent class: Class
  intersection of: neutrophil
  intersection of: Restriction
    on property: BFO_0000051
    some values from: CL_0017500
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0070820
  intersection of: Restriction
    on property: BFO_0000051
    some values from: Class
      intersection of: GO_0005634
      intersection of: Restriction
        on property: RO_0000053
        some values from: PATO_0001979
  intersection of: Restriction
    on property: lacks_part
    some values from: PR_000009978
  intersection of: Restriction
    on property: lacks_part
    some values from: PR_000010543
  intersection of: Restriction
    on property: lacks_part
    some values from: PR_000010799
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001256
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001257
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001456
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001483
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001879
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001944
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000007597
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002536
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002690
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0006909
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032637
subclass of: phagocyte
subclass of: neutrophil
subclass of: Restriction
  on property: BFO_0000051
  some values from: CL_0017500
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0070820
subclass of: Restriction
  on property: BFO_0000051
  some values from: Class
    intersection of: GO_0005634
    intersection of: Restriction
      on property: RO_0000053
      some values from: PATO_0001979
subclass of: Restriction
  on property: lacks_part
  some values from: PR_000009978
subclass of: Restriction
  on property: lacks_part
  some values from: PR_000010543
subclass of: Restriction
  on property: lacks_part
  some values from: PR_000010799
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001256
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001257
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001456
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001483
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001944
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000007597
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002536
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002690
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032637
IAO_0000115: A fully differentiated neutrophil, a granular leukocyte having a nucleus with three to five lobes connected by slender threads, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. They are produced in bone marrow at a rate of 5e10-10e10/day and have a half-life of 6-8 hours. Neutrophils are CD15-positive, CD16-positive, CD32-positive, CD43-positive, CD181-positive, and CD182-positive.
has broad synonym: poly
has broad synonym: polymorphonuclear leucocyte
has broad synonym: polymorphonuclear leukocyte
has exact synonym: PMN
has exact synonym: mature neutrocyte
has exact synonym: mature neutrophil leucocyte
has exact synonym: mature neutrophil leukocyte
has exact synonym: mature neutrophilic leucocyte
has exact synonym: mature neutrophilic leukocyte
has exact synonym: polymorphonuclear neutrophil
has exact synonym: polynuclear neutrophilic leucocyte
has exact synonym: polynuclear neutrophilic leukocyte

mast cell
type: Class
equivalent class: Class
  intersection of: myeloid leukocyte
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0030141
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001865
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001255
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000006169
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002349
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002539
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002660
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002690
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002830
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030210
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000002065
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000007431
subclass of: myeloid leukocyte
subclass of: histamine secreting cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0030141
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001865
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001255
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000006169
subclass of: Restriction
  on property: RO_0002202
  some values from: mast cell progenitor
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002349
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002539
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002660
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002690
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002830
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030210
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000002065
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000007431
IAO_0000115: A cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. Progenitors leave bone marrow and mature in connective and mucosal tissue. Mature mast cells are found in all tissues, except the bloodstream. Their phenotype is CD117-high, CD123-negative, CD193-positive, CD200R3-positive, and FceRI-high. Stem-cell factor (KIT-ligand; SCF) is the main controlling signal of their survival and development.
has exact synonym: histaminocyte
has exact synonym: labrocyte
has exact synonym: mastocyte
has related synonym: tissue basophil

sensory epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0050906
subclass of: epithelial cell
subclass of: sensory receptor cell
IAO_0000115: A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells.
has broad synonym: neuroepithelial cell

interneuron
type: Class
subclass of: neuron
IAO_0000115: Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions.

motor neuron
type: Class
subclass of: efferent neuron
IAO_0000115: An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement.
has exact synonym: motoneuron

sensory neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0050906
subclass of: afferent neuron
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0050906
IAO_0000115: Any neuron having a sensory function; an afferent neuron conveying sensory impulses.

bipolar neuron
type: Class
equivalent class: Class
  intersection of: interneuron
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0070006
subclass of: interneuron
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0070006
IAO_0000115: A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body.

multipolar neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0070026
subclass of: neuron
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0070026
IAO_0000115: A neuron with three or more neurites, usually an axon and multiple dendrites.

unipolar neuron
type: Class
subclass of: neuron
IAO_0000115: Neuron with one neurite that extends from the cell body.

autonomic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: RO_0002100
    some values from: UBERON_0002410
subclass of: CL_2000032
subclass of: Restriction
  on property: RO_0002100
  some values from: UBERON_0002410
IAO_0000115: A neuron whose cell body is within an autonomic ganglion.

cholinergic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0014055
subclass of: secretory cell
subclass of: neuron
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0014055
IAO_0000115: A neuron that uses acetylcholine as a vesicular neurotransmitter.

mononuclear phagocyte
type: Class
equivalent class: Class
  intersection of: phagocyte (sensu Vertebrata)
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001407
subclass of: phagocyte (sensu Vertebrata)
subclass of: mononuclear cell
IAO_0000115: A vertebrate phagocyte with a single nucleus.

surface ectodermal cell
type: Class
subclass of: ectodermal cell
has exact synonym: cell of surface ectoderm
has exact synonym: surface ectoderm cell

endothelial cell
type: Class
subclass of: BFO_0000002
subclass of: lining cell
subclass of: Restriction
  on property: RO_0002202
  some values from: mesodermal cell
IAO_0000115: An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm.
has exact synonym: endotheliocyte

CNS neuron (sensu Vertebrata)
type: Class
subclass of: BFO_0000002
subclass of: neuron
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001017
subclass of: Restriction
  on property: RO_0002202
  some values from: neuroblast (sensu Vertebrata)

cerebellar Golgi cell
type: Class
subclass of: CL_4023057
IAO_0000115: Large intrinsic neuron located in the granule layer of the cerebellar cortex that extends its dendrites into the molecular layer where they receive contact from parallel fibers. The axon of the Golgi cell ramifies densely in the granule layer and enters into a complex arrangement with mossy fiber terminals and granule cell dendrites to form the cerebellar glomerulus. Llinas, Walton and Lang. In The Synaptic Organization of the Brain. 5th ed. 2004.
has exact synonym: Golgi cell
has exact synonym: Golgi neuron
has exact synonym: cerebellar Golgi neuron
has exact synonym: cerebellum Golgi cell

granule cell
type: Class
subclass of: CNS neuron (sensu Vertebrata)
IAO_0000115: A neuron of the vertebrate central nervous system that is small in size. This general class includes small neurons in the granular layer of the cerebellar cortex, cerebral cortex neurons that are not pyramidal cells and small neurons without axons found in the olfactory bulb.

Purkinje cell
type: Class
subclass of: CNS neuron (sensu Vertebrata)
subclass of: efferent neuron
subclass of: CL_1001611
subclass of: Restriction
  on property: RO_0002100
  some values from: UBERON_0002129
IAO_0000115: The output neuron of the cerebellar cortex.
has exact synonym: Purkinje neuron
has exact synonym: Purkinje's cell
has exact synonym: cerebellar Purkinje cell
has exact synonym: cerebellum Purkinje cell

stellate neuron
type: Class
equivalent class: Class
  intersection of: CNS neuron (sensu Vertebrata)
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0070010
subclass of: multipolar neuron
subclass of: CNS neuron (sensu Vertebrata)
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0070010
IAO_0000115: A neuron that has dendritic processes radiating from the cell body forming a star-like shape.

neuron associated cell (sensu Vertebrata)
type: Class
subclass of: neuron associated cell
subclass of: eukaryotic cell
subclass of: Restriction
  on property: RO_0002160
  some values from: NCBITaxon 7742
subclass of: Restriction
  on property: RO_0002202
  some values from: migratory neural crest cell

glial cell
type: Class
subclass of: neuron associated cell
IAO_0000115: A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons.
has exact synonym: neuroglial cell
has related synonym: neuroglia

macroglial cell
type: Class
subclass of: glial cell
subclass of: Restriction
  on property: RO_0002202
  some values from: glioblast (sensu Vertebrata)
IAO_0000115: A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together.
has exact synonym: macrogliocyte
has related synonym: macroglia

astrocyte
type: Class
subclass of: macroglial cell
IAO_0000115: A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury.
has exact synonym: astrocytic glia

oligodendrocyte
type: Class
subclass of: macroglial cell
subclass of: CL_4023154
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001017
subclass of: Restriction
  on property: RO_0002202
  some values from: oligodendrocyte precursor cell
IAO_0000115: A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system.
has exact synonym: OLs
has related synonym: oligodendroglia

microglial cell
type: Class
equivalent class: Class
  intersection of: glial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001017
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001012
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001813
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002064
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0045087
subclass of: glial cell
subclass of: central nervous system macrophage
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001012
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001813
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002064
subclass of: Restriction
  on property: RO_0002202
  some values from: mesodermal cell
subclass of: Restriction
  on property: RO_0002202
  some values from: Class
    intersection of: stem cell
    intersection of: Restriction
      on property: BFO_0000050
      some values from: UBERON_0001040
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0045087
IAO_0000115: A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive.
has broad synonym: brain macrophage
has exact synonym: brain-resident macrophage
has exact synonym: hortega cells
has exact synonym: microgliocyte
has related synonym: MF.microglia.CNS
has related synonym: microglia

neurectodermal cell
type: Class
subclass of: ectodermal cell
IAO_0000115: Ectoderm destined to be nervous tissue.
has exact synonym: neurectoderm cell

mesenchymal stem cell
type: Class
subclass of: multi fate stem cell
subclass of: connective tissue cell
IAO_0000115: A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs.
has narrow synonym: bone marrow stromal cells
has narrow synonym: colony-forming unit-fibroblast
has narrow synonym: marrow stromal cells
has related synonym: BMSC
has related synonym: CFU-F
has related synonym: MSC
has related synonym: mesenchymal precursor cell
has related synonym: mesenchymal progenitor cells
has related synonym: mesenchymal stem cell
has related synonym: mesenchymal stromal cell
has related synonym: mesenchymal stromal cells
has related synonym: stem cells, mesenchymal

fibrocyte
type: Class
equivalent class: Class
  intersection of: stromal cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002495
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0045766
subclass of: stromal cell
subclass of: Restriction
  on property: RO_0002202
  some values from: fibroblast
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002495
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0045766
IAO_0000115: An inactive fibroblast; cytoplasm is sparse, endoplasmic reticulum is scanty with flattened nucleus. Term used by some histologists; when fibroblasts become relatively inactive in fiber formation. However, this cell has the potential for fibrogenesis in quiescent connective tissue of the adult, as well as during development, other histologists prefer to use the term fibroblast in all circumstances. These cells represent ~0.5% of peripheral blood leukocytes.

adipocyte
type: Class
subclass of: BFO_0000002
subclass of: stuff accumulating cell
subclass of: connective tissue cell
subclass of: Restriction
  on property: RO_0002202
  some values from: mesenchymal stem cell
IAO_0000115: A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides.
has exact synonym: adipose cell
has exact synonym: fat cell

chondrocyte
type: Class
subclass of: glycosaminoglycan secreting cell
subclass of: collagen secreting cell
subclass of: Restriction
  on property: RO_0001025
  some values from: UBERON_0002418
subclass of: Restriction
  on property: RO_0002202
  some values from: chondroblast
IAO_0000115: Skeletogenic cell that is terminally differentiated, secretes an avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell.
has exact synonym: cartilage cell

professional antigen presenting cell
type: Class
equivalent class: Class
  intersection of: leukocyte
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002504
subclass of: leukocyte
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002504
IAO_0000115: A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response.
has related synonym: APC

simple columnar epithelial cell
type: Class
subclass of: columnar/cuboidal epithelial cell

pigment cell
type: Class
subclass of: stuff accumulating cell
IAO_0000115: A pigment cell is a cell that contains pigment granules.
has exact synonym: chromatocyte
has exact synonym: chromatophore

melanocyte
type: Class
equivalent class: Class
  intersection of: pigment cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0042470
  intersection of: Restriction
    on property: RO_0002202
    some values from: melanoblast
subclass of: BFO_0000002
subclass of: pigment cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0042470
subclass of: Restriction
  on property: RO_0002202
  some values from: melanoblast
IAO_0000115: A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance.
has narrow synonym: melanophore

visual pigment cell
type: Class
subclass of: pigment cell
has broad synonym: pigment cell

glandular epithelial cell
type: Class
subclass of: epithelial cell
subclass of: secretory cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0006799
IAO_0000115: A specialized epithelial cell that is capable of synthesizing and secreting certain biomolecules.

secretory cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032940
subclass of: cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032940
IAO_0000115: A cell that specializes in controlled release of one or more substances.

exocrine cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002365
subclass of: secretory cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002365
IAO_0000115: A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct.

glycosaminoglycan secreting cell
type: Class
subclass of: extracellular matrix secreting cell
subclass of: carbohydrate secreting cell
IAO_0000115: A cell that secretes glycosaminoglycans.
has exact synonym: GAG secreting cell
has narrow synonym: hyaluronic acid secreting cell

protein secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0009306
subclass of: secretory cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0009306
IAO_0000115: Any secretory cell that is capable of some protein secretion.

surfactant secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0043129
subclass of: secretory cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0043129
IAO_0000115: A cell that specializes in secretion of surfactant in the alveoli of the lung.

club cell
type: Class
subclass of: surfactant secreting cell
subclass of: epithelial cell of tracheobronchial tree
subclass of: CL_0011026
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0005902
IAO_0000115: A non-mucous, epithelial secretory cell that is part of the tracheobronchial tree. A club cell has short microvilli but no cilia. A club cell is able to multiply and differentiate into ciliated cells to regenerate the bronchiolar epithelium and it also protects the tracheobronchial epithelium.
has exact synonym: Clara cell

seromucus secreting cell
type: Class
subclass of: secretory cell

goblet cell
type: Class
subclass of: glandular epithelial cell
subclass of: mucus secreting cell
IAO_0000115: A cell of the epithelial lining that produce and secrete mucins.
has exact synonym: chalice cell

endocrine cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: Class
      intersection of: GO_0046879
      intersection of: Restriction
        on property: RO_0002339
        some values from: UBERON_0001009
subclass of: secretory cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000949
subclass of: Restriction
  on property: RO_0002215
  some values from: Class
    intersection of: GO_0046879
    intersection of: Restriction
      on property: RO_0002339
      some values from: UBERON_0001009
IAO_0000115: A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions.
has exact synonym: endocrinocyte

enteroendocrine cell
type: Class
subclass of: glandular epithelial cell
subclass of: endocrine cell
IAO_0000115: An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas.

neuroendocrine cell
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0046879
subclass of: endocrine cell
subclass of: efferent neuron
subclass of: neurecto-epithelial cell
IAO_0000115: A neuron that is capable of some hormone secretion in response to neuronal signals.
has related synonym: neurosecretory cell
has related synonym: neurosecretory neuron

chromaffin cell
type: Class
subclass of: neural crest derived neuron
subclass of: amine precursor uptake and decarboxylation cell
IAO_0000115: A cell that stores epinephrine secretory vesicles. During times of stress, the nervous system signals the vesicles to secrete their hormonal content. Their name derives from their ability to stain a brownish color with chromic salts. Characteristically, they are located in the adrenal medulla and paraganglia of the sympathetic nervous system.
has exact synonym: phaeochromocyte

peptide hormone secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030072
subclass of: secretory cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030072
IAO_0000115: Any secretory cell that is capable of some peptide hormone secretion.

insulin secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030073
subclass of: protein secreting cell
subclass of: peptide hormone secreting cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030073
IAO_0000115: Any secretory cell that is capable of some insulin secretion.

type B pancreatic cell
type: Class
equivalent class: Class
  intersection of: enteroendocrine cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000006
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030073
subclass of: insulin secreting cell
subclass of: CL_0008024
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000006
subclass of: Restriction
  on property: RO_0002202
  some values from: progenitor cell of endocrine pancreas
IAO_0000115: A cell that secretes insulin and is located towards the center of the islets of Langerhans.
has broad synonym: beta cell
has exact synonym: B-cell of pancreatic islet
has exact synonym: beta cell of pancreatic islet
has exact synonym: insulin-secreting cell
has exact synonym: pancreatic B cell
has exact synonym: pancreatic B-cell
has exact synonym: pancreatic beta cell
has exact synonym: pancreatic islet core
has exact synonym: type B enteroendocrine cell
has related synonym: beta cell islet

glucagon secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0070091
subclass of: peptide hormone secreting cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0070091
IAO_0000115: A cell that secretes glucagon.
has exact synonym: glucagon-secreting cell

pancreatic A cell
type: Class
equivalent class: Class
  intersection of: type A enteroendocrine cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001264
subclass of: type A enteroendocrine cell
subclass of: CL_0008024
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000006
subclass of: Restriction
  on property: RO_0002202
  some values from: progenitor cell of endocrine pancreas
IAO_0000115: A type of enteocrine cell found in the periphery of the islets of Langerhans that secretes glucagon.
has exact synonym: alpha cell of islet of Langerhans
has exact synonym: pancreatic alpha cell

somatostatin secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0070253
subclass of: peptide hormone secreting cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0070253
IAO_0000115: Any secretory cell that is capable of some somatostatin secretion.

pancreatic D cell
type: Class
equivalent class: Class
  intersection of: type D enteroendocrine cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001264
subclass of: type D enteroendocrine cell
subclass of: CL_0008024
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000006
subclass of: Restriction
  on property: RO_0002202
  some values from: progenitor cell of endocrine pancreas
IAO_0000115: A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin.
has exact synonym: D-cell of pancreatic islet
has exact synonym: delta cell of islet
has exact synonym: delta cell of pancreatic islet
has exact synonym: pancreatic D-cell
has exact synonym: pancreatic delta cell
has exact synonym: somatostatin-secreting pancreatic cell

steroid hormone secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0035929
subclass of: secretory cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0035929
IAO_0000115: Any secretory cell that is capable of some steroid hormone secretion.

luteal cell
type: Class
subclass of: progesterone secreting cell
subclass of: stromal cell of ovary
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002512
IAO_0000115: A progesterone secreting cell in the corpus luteum. The large luteal cells develop from the granulosa cells. The small luteal cells develop from the theca cells.
has exact synonym: corpus luteum cell
has exact synonym: lutein cell

ecdysteroid secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0045457
subclass of: steroid hormone secreting cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0045457
IAO_0000115: Any secretory cell that is capable of some ecdysteroid secretion.

testosterone secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0035936
subclass of: secretory cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0035936
IAO_0000115: Any secretory cell that is capable of some testosterone secretion.

Leydig cell
type: Class
subclass of: BFO_0000002
subclass of: testosterone secreting cell
subclass of: CL_4030031
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0005212
subclass of: Restriction
  on property: RO_0002202
  some values from: CL_0009091
IAO_0000115: A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis.
has broad synonym: interstitial cell
has exact synonym: interstitial cell of Leydig

progesterone secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0042701
subclass of: steroid hormone secreting cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0042701
IAO_0000115: Any secretory cell that is capable of some progesterone secretion.

estradiol secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0035938
subclass of: steroid hormone secreting cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0035938
IAO_0000115: A steroid hormone secreting cell that secretes estradiol.

hepatocyte
type: Class
subclass of: BFO_0000002
subclass of: epithelial cell
subclass of: endopolyploid cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002107
subclass of: Restriction
  on property: RO_0002202
  some values from: CL_0005026
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0006699
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0098754
IAO_0000115: The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated.

contractile cell
type: Class
subclass of: cell
IAO_0000115: A cell whose primary function is to shorten.

myofibroblast cell
type: Class
subclass of: contractile cell
subclass of: connective tissue cell
IAO_0000115: An animal cell that has characteristics of both a fibroblast cell and a smooth muscle cell.
has exact synonym: MFB

muscle cell
type: Class
subclass of: BFO_0000002
subclass of: contractile cell
subclass of: electrically responsive cell
subclass of: Restriction
  on property: RO_0002202
  some values from: myoblast
IAO_0000115: A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.
has exact synonym: muscle fiber
has exact synonym: myocyte

cell of skeletal muscle
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001134
subclass of: cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001134
IAO_0000115: A somatic cell located in skeletal muscle.
has exact synonym: skeletal muscle cell

slow muscle cell
type: Class
subclass of: CL_0008046
subclass of: Restriction
  on property: RO_0002202
  some values from: slow muscle myoblast
IAO_0000115: A muscle cell that develops tension more slowly than a fast-twitch fiber.
has related synonym: slow muscle fiber

smooth muscle cell
type: Class
subclass of: CL_0008000
subclass of: CL_0008007
subclass of: Restriction
  on property: RO_0002202
  some values from: smooth muscle myoblast
IAO_0000115: A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast).
has broad synonym: non-striated muscle cell
has exact synonym: SMCs
has exact synonym: myocytes, smooth muscle
has exact synonym: smooth muscle fiber

sensory receptor cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001032
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0050906
subclass of: cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001032
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0050906
IAO_0000115: A cell that is capable of detection of a stimulus involved in sensory perception.
has exact synonym: receptor cell

mechanoreceptor cell
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0050974
subclass of: sensory neuron
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0050974
IAO_0000115: A cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system.
has related synonym: mechanoreceptor

touch receptor cell
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0050976
subclass of: mechanoreceptor cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0050976
IAO_0000115: Any neuron that is capable of some detection of mechanical stimulus involved in sensory perception of touch.

auditory hair cell
type: Class
subclass of: sensory hair cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0050910
IAO_0000115: A mechanoreceptor cell of the auditory or vestibular system that is sensitive to auditory stimuli. The accessory sensory structures are arranged so that appropriate stimuli cause movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system.
has related synonym: auditory receptor cell

gravity sensitive cell
type: Class
equivalent class: Class
  intersection of: neuronal receptor cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0070999
subclass of: neuronal receptor cell
subclass of: mechanoreceptor cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0070999
IAO_0000115: Any neuronal receptor cell that is capable of some detection of mechanical stimulus involved in sensory perception of gravity.

thermoreceptor cell
type: Class
equivalent class: Class
  intersection of: neuronal receptor cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0050960
subclass of: neuronal receptor cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0050960
IAO_0000115: A cellular receptor which mediates the sense of temperature. Thermoreceptor cells in vertebrates are mostly located under the skin. In mammals there are separate types of thermoreceptors for cold and for warmth and pain receptor cells which detect cold or heat extreme enough to cause pain.

chemoreceptor cell
type: Class
equivalent class: Class
  intersection of: sensory receptor cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0050907
subclass of: sensory receptor cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0050907
IAO_0000115: A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood.

olfactory receptor cell
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0050911
subclass of: neuronal receptor cell
subclass of: chemoreceptor cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0005725
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0050911
IAO_0000115: Any neuron that is capable of some detection of chemical stimulus involved in sensory perception of smell.
has exact synonym: Schultze's cell
has exact synonym: odorant receptor cell
has exact synonym: olfactory receptor neuron
has exact synonym: olfactory sensory neuron

taste receptor cell
type: Class
equivalent class: Class
  intersection of: chemoreceptor cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0050912
subclass of: sensory epithelial cell
subclass of: chemoreceptor cell
subclass of: endo-epithelial cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0050912
IAO_0000115: A specialized cell involved in gustatory sensory perception.
has exact synonym: taste bud cell

photoreceptor cell
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0050962
subclass of: neuronal receptor cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0050962
IAO_0000115: A cell specialized to detect and transduce light.

electrically active cell
type: Class
subclass of: cell
IAO_0000115: A cell whose function is determined by the generation or the reception of an electric signal.

lining cell
type: Class
subclass of: barrier cell
IAO_0000115: A cell within an epithelial cell sheet whose main function is to act as an internal or external covering for a tissue or an organism.
has exact synonym: boundary cell

synovial cell
type: Class
subclass of: lining cell
subclass of: meso-epithelial cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002217
IAO_0000115: A cell located in the synovial joint.
has exact synonym: synoviocyte

barrier cell
type: Class
subclass of: cell
IAO_0000115: A cell whose primary function is to prevent the transport of stuff across compartments.

Sertoli cell
type: Class
equivalent class: Class
  intersection of: supporting cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001343
subclass of: androgen binding protein secreting cell
subclass of: supporting cell
subclass of: CL_0002625
IAO_0000115: A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier.

insulating cell
type: Class
subclass of: barrier cell

myelinating Schwann cell
type: Class
subclass of: insulating cell
subclass of: CL_0002573
subclass of: CL_4023154
subclass of: Restriction
  on property: RO_0002202
  some values from: immature Schwann cell
IAO_0000115: A neuroglial cell of the peripheral nervous system which forms the insulating myelin sheaths of peripheral axons.
has broad synonym: Schwann cell
has broad synonym: peripheral neuroglial cell
has exact synonym: neurilemmal cell

motile cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0048870
subclass of: cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0048870
IAO_0000115: A cell that moves by its own activities.

ectodermal cell
type: Class
subclass of: embryonic cell (metazoa)
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000924
IAO_0000115: A cell of the outer of the three germ layers of the embryo.
has exact synonym: ectoderm cell

mesodermal cell
type: Class
subclass of: embryonic cell (metazoa)
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000926
IAO_0000115: A cell of the middle germ layer of the embryo.
has exact synonym: mesoblast
has exact synonym: mesoderm cell

endodermal cell
type: Class
subclass of: embryonic cell (metazoa)
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000925
IAO_0000115: A cell of the inner of the three germ layers of the embryo.
has exact synonym: endoderm cell

anucleate cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001405
subclass of: cell
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0001405
disjoint with: nucleate cell
IAO_0000115: A cell that lacks a nucleus.
has exact synonym: non-nucleated cell

single nucleate cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001407
subclass of: nucleate cell
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0001407
IAO_0000115: A cell with a single nucleus.

binucleate cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001406
subclass of: multinucleate cell
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0001406
IAO_0000115: Any cell that has characteristic some binucleate.

multinucleate cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001908
subclass of: nucleate cell
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0001908
IAO_0000115: A cell with more than one nucleus.
has exact synonym: syncitium
has exact synonym: syncytial cell
has exact synonym: syncytium

erythrocyte
type: Class
equivalent class: Class
  intersection of: erythroid lineage cell
  intersection of: Restriction
    on property: lacks_part
    some values from: GO_0005840
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001945
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0002039
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0008015
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0015671
subclass of: blood cell
subclass of: oxygen accumulating cell
subclass of: erythroid lineage cell
subclass of: Restriction
  on property: lacks_part
  some values from: GO_0005840
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001945
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0002039
subclass of: Restriction
  on property: RO_0002202
  some values from: reticulocyte
IAO_0000115: A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.
has exact synonym: RBC
has exact synonym: red blood cell

platelet
type: Class
subclass of: blood cell
subclass of: anucleate cell
subclass of: serotonin secreting cell
subclass of: myeloid cell
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0001874
subclass of: Restriction
  on property: RO_0002202
  some values from: megakaryocyte
subclass of: Restriction
  on property: RO_0002216
  some values from: GO_0007596
IAO_0000115: A non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.
has exact synonym: anucleate thrombocyte
has exact synonym: blood platelet
has exact synonym: enucleate thrombocyte

phagocyte
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0006909
subclass of: motile cell
subclass of: stuff accumulating cell
subclass of: defensive cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0006909
IAO_0000115: Any cell capable of ingesting particulate matter via phagocytosis.

macrophage
type: Class
equivalent class: Class
  intersection of: myeloid leukocyte
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002504
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0006909
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0031268
subclass of: mononuclear phagocyte
subclass of: professional antigen presenting cell
subclass of: myeloid leukocyte
subclass of: Restriction
  on property: RO_0002202
  some values from: monocyte
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0031268
IAO_0000115: A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells.
has exact synonym: histiocyte

B cell
type: Class
equivalent class: Class
  intersection of: lymphocyte of B lineage
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0019724
subclass of: lymphocyte of B lineage
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0019724
IAO_0000115: A lymphocyte of B lineage that is capable of B cell mediated immunity.
has exact synonym: B lymphocyte
has exact synonym: B-cell
has exact synonym: B-lymphocyte

keratinizing barrier epithelial cell
type: Class
subclass of: stratified squamous epithelial cell
subclass of: keratin accumulating cell
subclass of: ecto-epithelial cell
subclass of: Restriction
  on property: RO_0002202
  some values from: surface ectodermal cell

brush border epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0005903
subclass of: columnar/cuboidal epithelial cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0005903
IAO_0000115: An epithelial cell characterized by the presence of a brush border on its apical surface, which increases the surface area for absorption.

stratified squamous epithelial cell
type: Class
subclass of: squamous epithelial cell
subclass of: stratified epithelial cell

transitional epithelial cell
type: Class
subclass of: epithelial cell
IAO_0000115: A cell characteristically found lining hollow organs that are subject to great mechanical change due to contraction and distention; originally thought to represent a transition between stratified squamous and columnar epithelium.

Rohon-Beard neuron
type: Class
subclass of: neuronal receptor cell
subclass of: primary sensory neuron (sensu Teleostei)
subclass of: CL_4023168
IAO_0000115: Type of neuron that is a primary mechanosensory cell, with peripheral neurites innervating the skin with free nerve endings.
has exact synonym: Rohon Beard cell
has exact synonym: Rohon-Beard cell
has related synonym: RB neuron

eurydendroid cell
type: Class
subclass of: efferent neuron

eukaryotic cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: RO_0002160
    some values from: NCBITaxon 2759
subclass of: cell
subclass of: Restriction
  on property: RO_0002160
  some values from: NCBITaxon 2759
disjoint with: prokaryotic cell
IAO_0000115: Any cell that only exists in Eukaryota.

eye photoreceptor cell
type: Class
equivalent class: Class
  intersection of: photoreceptor cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000970
subclass of: photoreceptor cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000970
IAO_0000115: Any photoreceptor cell that is part of some eye.

somatotropin secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030252
subclass of: peptide hormone secreting cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030252
IAO_0000115: A peptide hormone secreting cell that produces growth hormone, somatotropin.
has exact synonym: growth hormone secreting cell
has exact synonym: somatotrophin secreting cell

gamete
type: Class
equivalent class: Class
  intersection of: germ cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001375
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0009566
subclass of: haploid cell
subclass of: germ cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0009566
IAO_0000115: A mature sexual reproductive cell having a single set of unpaired chromosomes.
has exact synonym: haploid nucleated cell
has related synonym: haploid germ cell

pole cell
type: Class
subclass of: primordial germ cell
IAO_0000115: A primordial germ cell of insects. Such cells form at the posterior pole of the early embryo.

crystallin accumulating cell
type: Class
subclass of: stuff accumulating cell
has exact synonym: lens cell

tracheal epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0003126
subclass of: epithelial cell of tracheobronchial tree
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0003126
subclass of: Restriction
  on property: RO_0002202
  some values from: tracheoblast
IAO_0000115: An epithelial cell found in the trachea.
has exact synonym: tracheocyte

keratin accumulating cell
type: Class
subclass of: stuff accumulating cell

keratinocyte
type: Class
equivalent class: Class
  intersection of: keratinizing barrier epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001003
subclass of: keratinizing barrier epithelial cell
subclass of: epidermal cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001003
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002775
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002776
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0090023
IAO_0000115: An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell.
has exact synonym: keratinized cell of epidermis
has exact synonym: malpighian cell

milk secreting cell
type: Class
subclass of: secretory cell

sebum secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001821
subclass of: exocrine cell
subclass of: CL_2000021
IAO_0000115: A cell secreting sebun, an oily substance secreted by sebaceous glands, composed of keratin, fat, and cellular debris.
has exact synonym: sebocyte

mucus secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0070254
subclass of: seromucus secreting cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0070254
IAO_0000115: Any secretory cell that is capable of some mucus secretion.
has exact synonym: mucous cell

pulmonary alveolar epithelial cell
type: Class
subclass of: epithelial cell of lung
subclass of: CL_0010003
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0004821
IAO_0000115: An epithelial cell that lines the peripheral gas exchange region of the lungs of air-breathing vertebrates.
has exact synonym: alveolar epithelial cell
has exact synonym: pneumocyte
has exact synonym: pneumonocyte

stuff accumulating cell
type: Class
subclass of: cell
IAO_0000115: A cell that is specialised to accumulate a particular substance(s).

extracellular matrix secreting cell
type: Class
subclass of: stromal cell

oxygen accumulating cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0015671
subclass of: cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0015671
IAO_0000115: Any cell that is capable of some oxygen transport.

migratory neural crest cell
type: Class
subclass of: motile cell
subclass of: CL_0011012
subclass of: CL_0011026
subclass of: Restriction
  on property: RO_0002202
  some values from: CL_0007004
IAO_0000115: A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body.

neuroblast (sensu Nematoda and Protostomia)
type: Class
subclass of: neural stem cell
subclass of: eukaryotic cell
subclass of: Restriction
  on property: RO_0002160
  some values from: NCBITaxon_33317
IAO_0000115: A neural precursor of the central nervous system.
has broad synonym: neuroblast

glioblast (sensu Vertebrata)
type: Class
subclass of: glioblast
subclass of: neuron associated cell (sensu Vertebrata)
subclass of: CL_0011026
IAO_0000115: An early neural cell developing from the early ependymal cell of the neural tube.
has exact synonym: spongioblast

pigment cell (sensu Nematoda and Protostomia)
type: Class
subclass of: pigment cell

extraembryonic cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000478
subclass of: cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000478
IAO_0000115: Any cell that is part of some extraembryonic structure.

amnioserosal cell
type: Class
equivalent class: Class
  intersection of: extraembryonic cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0010302
subclass of: extraembryonic cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0010302
IAO_0000115: Any extraembryonic cell that is part of some amnioserosa.

trophoblast cell
type: Class
subclass of: extraembryonic cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000358
IAO_0000115: A cell lining the outside of the blastocyst. After binding to the endometrium, trophoblast cells develop into two distinct layers, an inner layer of mononuclear cytotrophoblast cells and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblast cells, which form the early fetal-maternal interface.
has exact synonym: trophoblastic cell

multi-potent skeletal muscle stem cell
type: Class
equivalent class: Class
  intersection of: multi fate stem cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001134
subclass of: multi fate stem cell
subclass of: cell of skeletal muscle
IAO_0000115: A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell.

stratified epithelial stem cell
type: Class
subclass of: epithelial fate stem cell

vascular associated smooth muscle cell
type: Class
equivalent class: Class
  intersection of: smooth muscle cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002049
subclass of: smooth muscle cell
subclass of: CL_4033054
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002049
IAO_0000115: A smooth muscle cell associated with the vasculature.
has exact synonym: VSMC
has exact synonym: vascular smooth muscle cell

epidermal cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0007376
subclass of: general ecto-epithelial cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0007376
IAO_0000115: An epithelial cell of the integument (the outer layer of an organism).
has exact synonym: cell of epidermis
has narrow synonym: epithelial cell of skin

animal zygote
type: Class
equivalent class: Class
  intersection of: CL_0010017
  intersection of: Restriction
    on property: RO_0002160
    some values from: NCBITaxon_33208
subclass of: early embryonic cell (metazoa)
subclass of: eukaryotic cell
subclass of: CL_0010017
subclass of: Restriction
  on property: RO_0002160
  some values from: NCBITaxon_33208
IAO_0000115: Diploid cell produced by the fusion of sperm cell nucleus and egg cell.
has broad synonym: zygote

histoblast
type: Class
subclass of: eukaryotic cell
subclass of: CL_0011026
subclass of: Restriction
  on property: RO_0002160
  some values from: NCBITaxon_50557
IAO_0000115: A progenitor cell found in the larval epidermis of insects and that gives rise to the adult abdominal epidermis.

tracheoblast
type: Class
subclass of: branched duct epithelial cell

prohemocyte (sensu Nematoda and Protostomia)
type: Class
subclass of: CL_0008001
IAO_0000115: A precursor of mature hemocytes.

attachment cell
type: Class
subclass of: supporting cell

hemocyte (sensu Arthropoda)
type: Class
subclass of: BFO_0000002
subclass of: eukaryotic cell
subclass of: blood cell (sensu Nematoda and Protostomia)
subclass of: Restriction
  on property: RO_0002160
  some values from: NCBITaxon 6656
subclass of: Restriction
  on property: RO_0002202
  some values from: prohemocyte (sensu Nematoda and Protostomia)
IAO_0000115: A blood cell of the circulatory system of arthropods.

tendon cell
type: Class
equivalent class: Class
  intersection of: fibrocyte
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000043
subclass of: fibrocyte
subclass of: attachment cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000043
IAO_0000115: An elongated fibrocyte that is part of a tendon. The cytoplasm is stretched between the collagen fibres of the tendon. They have a central cell nucleus with a prominent nucleolus. Tendon cells have a well-developed rough endoplasmic reticulum and they are responsible for synthesis and turnover of tendon fibres and ground substance.
has exact synonym: muscle attachment cell
has related synonym: tenocyte

blood cell (sensu Nematoda and Protostomia)
type: Class
subclass of: blood cell

crystal cell
type: Class
subclass of: hemocyte (sensu Arthropoda)
subclass of: Restriction
  on property: RO_0002202
  some values from: procrystal cell
IAO_0000115: A hemocyte that synthesizes and secretes melanins as part of the antimicrobial immune response. It is characterized morphologically by crystal inclusions of phenoloxidases in its cytoplasm, hence its name.

electrically responsive cell
type: Class
subclass of: electrically active cell
IAO_0000115: A cell whose function is determined by its response to an electric signal.

plasmatocyte
type: Class
subclass of: hemocyte (sensu Arthropoda)
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0035010
IAO_0000115: A phagocytic hemocyte, responsible for the engulfment of small particles, microbes, and apoptotic tissue debris. It may also secretes antimicrobial peptides and contribute to the production and secretion of proteins of the hemolymph.
has related synonym: macrophage

procrystal cell
type: Class
subclass of: prohemocyte (sensu Nematoda and Protostomia)
IAO_0000115: A precursor of mature crystal cells.

lamellocyte
type: Class
subclass of: hemocyte (sensu Arthropoda)
IAO_0000115: A hemocyte found in immuno-stimulated larvae.

ganglion interneuron
type: Class
equivalent class: Class
  intersection of: interneuron
  intersection of: Restriction
    on property: RO_0002100
    some values from: UBERON_0000045
subclass of: interneuron
subclass of: Restriction
  on property: RO_0002100
  some values from: UBERON_0000045
IAO_0000115: Any interneuron that has its soma located in some ganglion.

CNS interneuron
type: Class
equivalent class: Class
  intersection of: interneuron
  intersection of: Restriction
    on property: RO_0002100
    some values from: UBERON_0001017
subclass of: interneuron
subclass of: CL_2000029
IAO_0000115: An interneuron that has its cell body in a central nervous system.

electrically signaling cell
type: Class
subclass of: electrically active cell
IAO_0000115: A cell that initiates an electrical signal and passes that signal to another cell.

male gamete
type: Class
equivalent class: Class
  intersection of: male germ cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001375
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0009566
subclass of: male germ cell
subclass of: gamete
IAO_0000115: Any male germ cell that has characteristic some haploid and is capable of some fertilization.

polyploid cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001377
subclass of: cell
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0001377
IAO_0000115: A cell that contains more than two haploid sets of chromosomes.

haploid cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001375
subclass of: cell
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0001375
IAO_0000115: A cell whose nucleus contains a single haploid genome.

endopolyploid cell
type: Class
subclass of: polyploid cell

mitogenic signaling cell
type: Class
subclass of: cell
IAO_0000115: A cell whose primary function is to cause growth by stimulating cell division in its immediate cellular environment.

tip cell
type: Class
subclass of: mitogenic signaling cell

excretory cell
type: Class
subclass of: secretory cell
IAO_0000115: A cell involved in the elimination of metabolic and foreign toxins, and in maintaining the ionic, acid-base and water balance of biological fluids.

xanthophore cell
type: Class
subclass of: BFO_0000002
subclass of: pigment cell
subclass of: Restriction
  on property: RO_0002202
  some values from: CL_0005002
IAO_0000115: A pigment cell derived from the neural crest. Contains cartenoid pigments in structures called pterinosomes or xanthosomes. This gives an appearance ranging from a golden yellow to orange and red.
has related synonym: xanthophore

iridophore
type: Class
subclass of: BFO_0000002
subclass of: pigment cell
subclass of: Restriction
  on property: RO_0002202
  some values from: CL_0005001
IAO_0000115: A pigment cell derived from the neural crest. The cell contains flat light-reflecting platelets, probably of guanine, in stacks called reflecting platelets or iridisomes. The color-generating components produce a silver, gold, or iridescent color.
has related synonym: guanophore

luteinizing hormone secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032275
subclass of: secretory cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032275
IAO_0000115: A peptide hormone secreting cell pituitary that produces luteinizing hormone.

prolactin secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0070459
subclass of: protein secreting cell
subclass of: peptide hormone secreting cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0070459
IAO_0000115: A peptide hormone cell that secretes prolactin.

melanocyte stimulating hormone secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0036160
subclass of: peptide hormone secreting cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0036160
IAO_0000115: A cell of the intermediate pituitary that produces melanocyte stimulating hormone.
has exact synonym: melanotrope
has exact synonym: melanotroph

follicle stem cell (sensu Arthropoda)
type: Class
subclass of: epithelial fate stem cell
subclass of: eukaryotic cell
subclass of: Restriction
  on property: RO_0002160
  some values from: NCBITaxon 6656
IAO_0000115: A stem cell that gives rise to the follicle cells that surround the oocyte in female arthropods.
has broad synonym: somatic stem cell

follicular dendritic cell
type: Class
subclass of: defensive cell
IAO_0000115: A cell with extensive dendritic processes found in the B cell areas (primary follicles and germinal centers) of lymphoid tissue. They are unrelated to the dendritic cell associated with T cells. Follicular dendritic cells have Fc receptors and C3b receptors, but unlike other dendritic cells, they do not process or present antigen in a way that allows recognition by T cells. Instead, they hold antigen in the form of immune complexes on their surfaces for long periods and can present antigen to B cells during an immune response.

calcitonin secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0036161
subclass of: peptide hormone secreting cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0036161
IAO_0000115: Any secretory cell that is capable of some calcitonin secretion.

carbohydrate secreting cell
type: Class
subclass of: secretory cell

white adipocyte
type: Class
subclass of: adipocyte
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001347
subclass of: Restriction
  on property: RO_0002202
  some values from: preadipocyte
IAO_0000115: An adipocyte with light coloration and few mitochondria. It contains a scant ring of cytoplasm surrounding a single large lipid droplet or vacuole.
has exact synonym: white adipose cell
has related synonym: white fat cell

brown adipocyte
type: Class
subclass of: adipocyte
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001348
subclass of: Restriction
  on property: RO_0002202
  some values from: brown preadipocyte
IAO_0000115: A cell from the thermogenic form of adipose tissue found in many species, particularly in newborns and hibernating mammals, but also in lesser amounts in adults of other mammals including humans. Brown fat is capable of rapid liberation of energy and seems to be important in the maintenance of body temperature immediately after birth and upon waking from hibernation.
has exact synonym: brown adipose cell
has exact synonym: brown fat cell

dendritic cell
type: Class
equivalent class: Class
  intersection of: leukocyte
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0042613
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001003
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001407
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0001816
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002504
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0019882
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0045580
subclass of: mononuclear phagocyte
subclass of: professional antigen presenting cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0042613
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001003
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0001816
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0045580
disjoint with: lymphocyte
IAO_0000115: A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative).
has related synonym: interdigitating cell
has related synonym: veiled cell

Langerhans cell
type: Class
equivalent class: Class
  intersection of: conventional dendritic cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001293
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002828
subclass of: myeloid leukocyte
subclass of: conventional dendritic cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001293
subclass of: Restriction
  on property: RO_0002202
  some values from: myeloid cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002828
IAO_0000115: Langerhans cell is a conventional dendritic cell that has plasma membrane part CD207. A Langerhans cell is a stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus.
has exact synonym: LC

epinephrine secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0048242
subclass of: biogenic amine secreting cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0048242
IAO_0000115: A cell capable of producing epinephrine. Epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme, which is expressed in the adrenal glands, androgenic neurons, and in other cell types.
has exact synonym: adrenaline secreting cell
has exact synonym: epinephrin secreting cell

mineralocorticoid secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0035931
subclass of: steroid hormone secreting cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0035931
IAO_0000115: Any secretory cell that is capable of some mineralocorticoid secretion.

biogenic amine secreting cell
type: Class
subclass of: secretory cell

serotonin secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0001820
subclass of: biogenic amine secreting cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0001820
IAO_0000115: A cell type that secretes 5-Hydroxytryptamine (serotonin).
has exact synonym: 5-HT secreting cell
has exact synonym: 5-Hydroxytryptamine secreting cell

noradrenergic cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0048243
subclass of: biogenic amine secreting cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0048243
IAO_0000115: A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme.
has exact synonym: noradrenaline secreting cell
has exact synonym: norepinephrin secreting cell
has exact synonym: norepinephrine secreting cell

glucocorticoid secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0035933
subclass of: steroid hormone secreting cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0035933
IAO_0000115: Any secretory cell that is capable of some glucocorticoid secretion.

adrenocorticotropic hormone secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0051458
subclass of: peptide hormone secreting cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0051458
IAO_0000115: A peptide hormone secreting cell that produces adrenocorticotropin, or corticotropin.
has exact synonym: ACTH secreting cell
has exact synonym: adrenocorticotrophic hormone secreting cell
has exact synonym: corticotrophin hormone secreting cell
has exact synonym: corticotropin hormone secreting cell
has exact synonym: corticotropin secreting cell

ganglion mother cell
type: Class
subclass of: BFO_0000002
subclass of: CL_0011020
subclass of: Restriction
  on property: RO_0002202
  some values from: neuroblast (sensu Nematoda and Protostomia)
IAO_0000115: A neural progenitor cell that is the daughter of a neuroblast (sensu arthopoda). The progeny of ganglion mother cells develop into neurons, glia and (occasionally) epithelial cells.

defensive cell
type: Class
subclass of: cell
IAO_0000115: A cell whose primary function is to protect the organism.

pericardial nephrocyte
type: Class
subclass of: phagocyte (sensu Nematoda and Protostomia)
subclass of: nephrocyte
IAO_0000115: An insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel.
has narrow synonym: pericardial cell

thyrotroph
type: Class
subclass of: basophil cell of pars distalis of adenohypophysis
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0070460
IAO_0000115: A basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin. This cell type is elongated, polygonal and lie in clusters towards the adenohypophyseal center.
has exact synonym: beta-basophil
has exact synonym: thyroid stimulating hormone secreting cell
has exact synonym: thyrotrope

follicle cell of egg chamber
type: Class
subclass of: BFO_0000002
subclass of: eukaryotic cell
subclass of: follicular epithelial cell
subclass of: CL_2000064
subclass of: Restriction
  on property: RO_0002160
  some values from: NCBITaxon_50557
subclass of: Restriction
  on property: RO_0002202
  some values from: follicle stem cell (sensu Arthropoda)
IAO_0000115: A somatic epithelial cell of the insect egg chamber.
has broad synonym: follicle cell
has broad synonym: ovarian follicle cell

juvenile hormone secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0045443
subclass of: secretory cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0045443
IAO_0000115: An endocrine cell that secretes juvenile hormone.

connective tissue type mast cell
type: Class
equivalent class: Class
  intersection of: mast cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002384
subclass of: mast cell
subclass of: connective tissue cell
IAO_0000115: Mast cell subtype whose granules contain both the serine proteases tryptase and chymase. These cells are primarily found in connective tissue, such as the peritoneal cavity, skin, and intestinal submucosa. Their development is T-cell independent.
has exact synonym: MC(TC)
has exact synonym: MCTC
has exact synonym: TC mast cells

mucosal type mast cell
type: Class
equivalent class: Class
  intersection of: mast cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001961
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002540
subclass of: mast cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001961
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002540
IAO_0000115: Mast cell subtype that contains only the serine protease trypase in its granules. These cells are primarily found in mucosal tissue, such as intestinal mucosa and alveoli. They depend upon T-cells for development of phenotype.
has exact synonym: MC(T)
has exact synonym: MCT
has exact synonym: T mast cells

garland cell
type: Class
subclass of: binucleate cell
subclass of: phagocyte (sensu Nematoda and Protostomia)
subclass of: nephrocyte
IAO_0000115: A large binucleate cell that forms a 'garland' around the anterior end of the proventriculus (cardia) at its junction with the esophagus in both adults and larvae flies. Each cell is surrounded by a basement membrane and there are numerous micro-invaginations (lacunae) extending from the surface into the cytoplasm. At the mouth of each lacuna is a doubled filament forming a specialised filtration system (diaphragm). The filtrate is endocytosed from the lacunae.
has broad synonym: garland nephrocyte

oenocyte
type: Class
subclass of: secretory cell
subclass of: eukaryotic cell
subclass of: Restriction
  on property: RO_0002160
  some values from: NCBITaxon 6656
IAO_0000115: A secretory cell of ectodermal origin. This cell may have important functions in fatty acid and hydrocarbon metabolism and is metabolically linked to the fat body and tracheae. This cell is exclusive of arthropods.

visible light photoreceptor cell
type: Class
equivalent class: Class
  intersection of: photoreceptor cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0009584
subclass of: photoreceptor cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0009584
IAO_0000115: A photoreceptor cell that detects visible light.

CD4-positive helper T cell
type: Class
equivalent class: Class
  intersection of: CD4-positive, alpha-beta T cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0001816
subclass of: CD4-positive, alpha-beta T cell
subclass of: Restriction
  on property: RO_0002202
  some values from: activated CD4-positive, alpha-beta T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0001816
subclass of: Restriction
  on property: RO_0002353
  some values from: GO_0030217
IAO_0000115: A CD4-positive, alpha-beta T cell that cooperates with other lymphocytes via direct contact or cytokine release to initiate a variety of immune functions.
has exact synonym: CD4-positive T-helper cell
has exact synonym: CD4-positive helper T lymphocyte
has exact synonym: CD4-positive helper T-cell
has exact synonym: CD4-positive helper T-lymphocyte

UV sensitive photoreceptor cell
type: Class
equivalent class: Class
  intersection of: photoreceptor cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0009589
subclass of: photoreceptor cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0009589
IAO_0000115: A photoreceptor cell that detects ultraviolet light.

inhibitory interneuron
type: Class
subclass of: interneuron
IAO_0000115: An interneuron (also called relay neuron, association neuron or local circuit neuron) is a multipolar neuron which connects afferent neurons and efferent neurons in neural pathways. Like motor neurons, interneuron cell bodies are always located in the central nervous system (CNS).

stromal cell
type: Class
subclass of: BFO_0000002
subclass of: connective tissue cell
subclass of: Restriction
  on property: RO_0002202
  some values from: mesenchymal stem cell
IAO_0000115: A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere.

follicular epithelial cell
type: Class
subclass of: epithelial cell
IAO_0000115: An epithelial somatic cell associated with a maturing oocyte.

granulosa cell
type: Class
subclass of: steroid hormone secreting cell
subclass of: follicular cell of ovary
subclass of: Restriction
  on property: RO_0002207
  some values from: CL_4033066
IAO_0000115: A supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors.
has exact synonym: granulosa cell of ovary

type D enteroendocrine cell
type: Class
subclass of: enteroendocrine cell
subclass of: somatostatin secreting cell
IAO_0000115: A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin.
has exact synonym: D cell

androgen binding protein secreting cell
type: Class
subclass of: protein secreting cell
IAO_0000115: A peptide hormone secreting cell that secretes androgen binding protein.

cardiac muscle myoblast
type: Class
equivalent class: Class
  intersection of: myoblast
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001133
  intersection of: Restriction
    on property: RO_0002203
    some values from: cardiac muscle cell
subclass of: cardiocyte
subclass of: CL_0010021
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001133
IAO_0000115: A precursor cell destined to differentiate into cardiac muscle cell.
has exact synonym: cardiac muscle progenitor cell
has exact synonym: cardiomyocyte progenitor cell

smooth muscle myoblast
type: Class
equivalent class: Class
  intersection of: myoblast
  intersection of: Restriction
    on property: RO_0002203
    some values from: smooth muscle cell
subclass of: myoblast
subclass of: Restriction
  on property: RO_0002203
  some values from: smooth muscle cell
IAO_0000115: A precursor cell destined to differentiate into smooth muscle myocytes.
has exact synonym: myoblast, smooth muscle
has related synonym: satellite cell

skeletal muscle myoblast
type: Class
equivalent class: Class
  intersection of: myoblast
  intersection of: Restriction
    on property: RO_0002203
    some values from: CL_0008002
subclass of: myoblast
subclass of: CL_0011026
subclass of: Restriction
  on property: RO_0002202
  some values from: multi-potent skeletal muscle stem cell
subclass of: Restriction
  on property: RO_0002203
  some values from: CL_0008002
IAO_0000115: A myoblast that differentiates into skeletal muscle fibers.
has exact synonym: skeletal myoblast

macrophage derived foam cell
type: Class
subclass of: BFO_0000002
subclass of: foam cell
subclass of: Restriction
  on property: RO_0002202
  some values from: macrophage
IAO_0000115: A type of foam cell derived from a macrophage containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions.
has exact synonym: lipophage

phagocyte (sensu Vertebrata)
type: Class
subclass of: phagocyte
subclass of: eukaryotic cell
subclass of: Restriction
  on property: RO_0002160
  some values from: NCBITaxon 7742
IAO_0000115: A phagocyte in vertebrates that is able to phagocytosis.

phagocyte (sensu Nematoda and Protostomia)
type: Class
subclass of: phagocyte
IAO_0000115: A phagocyte from organisms in the Nematoda or Protostomia clades.

prokaryotic cell
type: Class
subclass of: cell

fungal cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: RO_0002160
    some values from: NCBITaxon 4751
subclass of: eukaryotic cell
subclass of: Restriction
  on property: RO_0002160
  some values from: NCBITaxon 4751
IAO_0000115: Any cell that only exists in Fungi.

syncytiotrophoblast cell
type: Class
equivalent class: Class
  intersection of: trophoblast cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001908
subclass of: multinucleate cell
subclass of: trophoblast cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000371
IAO_0000115: A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo, directly associated with the maternal blood supply. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy.
has exact synonym: syncytial trophoblast cell
has exact synonym: syncytiotrophoblastic cell
has related synonym: plasmidotrophoblast cell
has related synonym: syntrophoblast cell

afferent neuron
type: Class
subclass of: neuron
IAO_0000115: A neuron which conveys sensory information centrally from the periphery.
has exact synonym: input neuron

efferent neuron
type: Class
subclass of: neuron
IAO_0000115: A neuron which sends impulses peripherally to activate muscles or secretory cells.
has exact synonym: output neuron

primary neuron (sensu Teleostei)
type: Class
subclass of: BFO_0000002
subclass of: eukaryotic cell
subclass of: neuron
subclass of: Restriction
  on property: RO_0002160
  some values from: NCBITaxon_32443
IAO_0000115: A neuron that develops during the early segmentation stages in teleosts, before the neural tube is formed.

primary sensory neuron (sensu Teleostei)
type: Class
equivalent class: Class
  intersection of: sensory neuron
  intersection of: primary neuron (sensu Teleostei)
subclass of: sensory neuron
subclass of: primary neuron (sensu Teleostei)
IAO_0000115: A primary neuron (sensu Teleostei) that has a sensory function.

neuron
type: Class
subclass of: electrically responsive cell
subclass of: electrically signaling cell
subclass of: neural cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0019226
IAO_0000115: The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
has exact synonym: nerve cell

melanoblast
type: Class
subclass of: non-terminally differentiated cell
subclass of: CL_0011026
subclass of: Restriction
  on property: RO_0002202
  some values from: migratory neural crest cell
IAO_0000115: A cell that originates from the neural crest and differentiates into a pigment cell.

lymphocyte
type: Class
equivalent class: Class
  intersection of: leukocyte
  intersection of: Restriction
    on property: BFO_0000051
    some values from: CL_0017500
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0000792
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001407
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0040072
subclass of: mononuclear cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: CL_0017500
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0000792
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0040072
subclass of: Restriction
  on property: RO_0002202
  some values from: common lymphoid progenitor
disjoint with: myeloid leukocyte
IAO_0000115: A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.

T-helper 1 cell
type: Class
equivalent class: Class
  intersection of: CD4-positive helper T cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000001835
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001202
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001207
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032609
subclass of: CD4-positive helper T cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000001835
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001202
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001207
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032609
IAO_0000115: A CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive, CXCR3-positive, CCR6-negative, and is capable of producing interferon-gamma.
has exact synonym: T helper cells type 1
has exact synonym: T(H)-1 cell
has exact synonym: Th1 CD4+ T cell
has exact synonym: Th1 T cell
has exact synonym: Th1 T lymphocyte
has exact synonym: Th1 T-cell
has exact synonym: Th1 T-lymphocyte
has exact synonym: Th1 cell
has exact synonym: helper T cell type 1

T-helper 2 cell
type: Class
equivalent class: Class
  intersection of: CD4-positive helper T cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000001941
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001202
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001207
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032633
subclass of: CD4-positive helper T cell
subclass of: CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000001941
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032633
IAO_0000115: A CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive, CXCR3-negative, CCR6-negative, and is capable of producing interleukin-4.
has exact synonym: T helper cells type 2
has exact synonym: T(H)-2 cell
has exact synonym: Th2 T cell
has exact synonym: Th2 T lymphocyte
has exact synonym: Th2 T-cell
has exact synonym: Th2 T-lymphocyte
has exact synonym: Th2 cell
has exact synonym: helper T cell type 2

proerythroblast
type: Class
equivalent class: Class
  intersection of: erythroid lineage cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: CL_0017503
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0005730
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0002505
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0040072
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001945
subclass of: erythroid lineage cell
subclass of: nucleate cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: CL_0017503
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0005730
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0040072
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001945
subclass of: Restriction
  on property: RO_0002202
  some values from: erythroid progenitor cell
IAO_0000115: An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers.
has exact synonym: rubriblast
has related synonym: pronormoblast

basophilic erythroblast
type: Class
equivalent class: Class
  intersection of: erythroblast
  intersection of: Restriction
    on property: BFO_0000051
    some values from: CL_0017503
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0000792
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001945
subclass of: erythroblast
subclass of: Restriction
  on property: BFO_0000051
  some values from: CL_0017503
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0000792
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001945
IAO_0000115: A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers.
has exact synonym: basophilic normoblast
has exact synonym: early erythroblast
has exact synonym: early normoblast
has exact synonym: prorubricyte

polychromatophilic erythroblast
type: Class
equivalent class: Class
  intersection of: erythroblast
  intersection of: Restriction
    on property: BFO_0000051
    some values from: CL_0017504
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0000792
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001945
subclass of: erythroblast
subclass of: Restriction
  on property: BFO_0000051
  some values from: CL_0017504
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0000792
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001945
subclass of: Restriction
  on property: RO_0002202
  some values from: basophilic erythroblast
IAO_0000115: A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers.
has exact synonym: intermediate erythroblast
has exact synonym: intermediate normoblast
has exact synonym: polychromatic erythroblast
has exact synonym: polychromatic normoblast
has exact synonym: polychromatophilic normoblast
has exact synonym: rubricyte

orthochromatic erythroblast
type: Class
equivalent class: Class
  intersection of: erythroblast
  intersection of: Restriction
    on property: BFO_0000051
    some values from: CL_0017502
  intersection of: Restriction
    on property: RO_0000056
    some values from: GO_0030263
subclass of: erythroblast
subclass of: Restriction
  on property: BFO_0000051
  some values from: CL_0017502
subclass of: Restriction
  on property: RO_0000056
  some values from: GO_0030263
subclass of: Restriction
  on property: RO_0002202
  some values from: polychromatophilic erythroblast
IAO_0000115: The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated.
has exact synonym: acidophilic erythroblast
has exact synonym: eosinophilic erythroblast
has exact synonym: late erythoblast
has exact synonym: orthochromatic normoblast
has exact synonym: pyknotic eto enrythroblast

megakaryocyte progenitor cell
type: Class
equivalent class: Class
  intersection of: myeloid lineage restricted progenitor cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002981
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0007113
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030219
subclass of: myeloid cell
subclass of: myeloid lineage restricted progenitor cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002981
subclass of: Restriction
  on property: RO_0002202
  some values from: megakaryocyte-erythroid progenitor cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0007113
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030219
IAO_0000115: The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative).
has exact synonym: CFU-Meg
has exact synonym: Meg-CFC
has exact synonym: MkP
has exact synonym: colony-forming unit-megakaryocyte
has exact synonym: megacaryoblast
has exact synonym: megacaryocyte progenitor cell
has exact synonym: megakaryoblast
has exact synonym: megakaryocytic progenitor cell
has related synonym: promegacaryocyte
has related synonym: promegakaryocyte

megakaryocyte
type: Class
subclass of: myeloid cell
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0001393
subclass of: Restriction
  on property: RO_0002202
  some values from: megakaryocyte progenitor cell
disjoint with: erythroid lineage cell
IAO_0000115: A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release.
has exact synonym: megacaryocyte
has exact synonym: megalocaryocyte
has exact synonym: megalokaryocyte

granulocyte monocyte progenitor cell
type: Class
equivalent class: Class
  intersection of: hematopoietic oligopotent progenitor cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002371
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000001944
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000005307
  intersection of: Restriction
    on property: lacks_part
    some values from: PR_000007857
  intersection of: Restriction
    on property: lacks_part
    some values from: PR_000007858
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001865
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030225
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030851
subclass of: myeloid cell
subclass of: CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor
subclass of: CL_0011026
subclass of: CL_1001610
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000001944
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000005307
subclass of: Restriction
  on property: lacks_part
  some values from: PR_000007857
subclass of: Restriction
  on property: lacks_part
  some values from: PR_000007858
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001865
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030225
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030851
IAO_0000115: A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata1 or Gata2 but do express C/EBPa, and Pu.1.
has broad synonym: CFU-C , Colony forming unit in culture
has exact synonym: colony forming unit granulocyte macrophage
has exact synonym: granulocyte-macrophage progenitor
has exact synonym: granulocyte/monocyte precursor
has exact synonym: granulocyte/monocyte progenitor
has related synonym: CFU-GM
has related synonym: GMP

reticulocyte
type: Class
equivalent class: Class
  intersection of: erythroid lineage cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001945
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0071971
subclass of: erythroid lineage cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001945
subclass of: Restriction
  on property: RO_0002202
  some values from: orthochromatic erythroblast
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0071971
IAO_0000115: An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds.

promonocyte
type: Class
equivalent class: Class
  intersection of: monopoietic cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0042582
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001012
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030224
subclass of: myeloid cell
subclass of: monopoietic cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0042582
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001012
subclass of: Restriction
  on property: RO_0002202
  some values from: monoblast
IAO_0000115: A precursor in the monocytic series, being a cell intermediate in development between the monoblast and monocyte. This cell is CD11b-positive and has fine azurophil granules.

amacrine cell
type: Class
subclass of: BFO_0000002
subclass of: interneuron
subclass of: CL_0009004
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000966
subclass of: Restriction
  on property: RO_0002120
  some values from: retinal ganglion cell
subclass of: Restriction
  on property: RO_0002162
  some values from: NCBITaxon 7742
IAO_0000115: Interneuron of the vertebrate retina. They integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. They lack large axons.
has exact synonym: amacrine neuron
has related synonym: AC
has related synonym: ACs

nucleate erythrocyte
type: Class
equivalent class: Class
  intersection of: erythrocyte
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0002505
subclass of: erythrocyte
subclass of: nucleate cell
subclass of: Restriction
  on property: RO_0002202
  some values from: nucleated reticulocyte
IAO_0000115: An erythrocyte having a nucleus.
has broad synonym: RBC
has broad synonym: red blood cell

endospore
type: Class
subclass of: prokaryotic cell
IAO_0000115: A rounded, inactive form that certain bacteria assume under conditions of extreme temperature, dryness, or lack of food. The bacterium develops a waterproof cell wall that protects it from being dried out or damaged.
has exact synonym: bacterial spore

neutrophilic promyelocyte
type: Class
equivalent class: Class
  intersection of: promyelocyte
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000001944
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000005307
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000007857
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000010543
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000014362
  intersection of: Restriction
    on property: lacks_part
    some values from: PR_000009978
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030223
subclass of: neutrophil progenitor cell
subclass of: promyelocyte
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000001944
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000005307
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000007857
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000010543
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000014362
subclass of: Restriction
  on property: lacks_part
  some values from: PR_000009978
subclass of: Restriction
  on property: RO_0002202
  some values from: neutrophilic myeloblast
IAO_0000115: A promyelocyte committed to the neutrophil lineage. This cell type is GATA-1-positive, C/EBPa-positive, AML-1-positive, MPO-positive, has low expression of PU.1 transcription factor and lacks lactotransferrin expression.
has exact synonym: neutrophilic premyelocyte
has exact synonym: neutrophilic progranulocyte

angioblastic mesenchymal cell
type: Class
equivalent class: Class
  intersection of: mesenchymal stem cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001444
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002112
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000016043
subclass of: mesenchymal stem cell
subclass of: CL_0011026
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001444
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002112
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000016043
subclass of: Restriction
  on property: RO_0002202
  some values from: mesenchymal stem cell
IAO_0000115: A mesenchymal stem cell capable of developing into blood vessel endothelium.
has exact synonym: angioblast
has exact synonym: chondroplast

amine precursor uptake and decarboxylation cell
type: Class
subclass of: neuroendocrine cell
IAO_0000115: A cell that originates in the neural crest, that has certain cytochemical and ultrastructural characteristics and is found scattered throughout the body; types include melanocytes, the cells of the chromaffin system, and cells in the hypothalamus, hypophysis, thyroid, parathyroids, lungs, gastrointestinal tract, and pancreas. This cell type concentrates the amino acid precursors of certain amines and decarboxylate them, forming amines that function as regulators and neurotransmitters. This cell type produces substances such as epinephrine, norepinephrine, dopamine, serotonin, enkephalin, somatostatin, neurotensin, and substance P, the actions of which may affect contiguous cells, nearby groups of cells, or distant cells, thus functioning as local or systemic hormones. The name is an acronym for amine precursor uptake and decarboxylation cell.
has exact synonym: APUD cell

cardiac mesenchymal cell
type: Class
equivalent class: Class
  intersection of: CL_0008019
  intersection of: Restriction
    on property: RO_0002203
    some values from: cardiocyte
subclass of: CL_0008019
subclass of: CL_2000073
subclass of: Restriction
  on property: RO_0002203
  some values from: cardiocyte
IAO_0000115: A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field.

parafollicular cell
type: Class
equivalent class: Class
  intersection of: neurecto-epithelial cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001024
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0001820
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0014046
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0036161
subclass of: calcitonin secreting cell
subclass of: serotonin secreting cell
subclass of: neurecto-epithelial cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001747
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001024
subclass of: Restriction
  on property: RO_0002202
  some values from: migratory neural crest cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0014046
IAO_0000115: A neuroepithelial cells that occurs singly or in small groups, close to the outer follicular borders but within the follicular basement membrane of the thyroid. Expresses a form of the neural cell adhesion molecule (N-CAM) on their surface. Secretes calcitonin, 5-hydroxytryptamine and dopamine.
has exact synonym: C cell
has exact synonym: C cell of thyroid gland
has exact synonym: clear cell of thyroid gland
has exact synonym: parafollicular cell of thyroid gland
has exact synonym: thyroid parafollicular cell

leucophore
type: Class
subclass of: BFO_0000002
subclass of: pigment cell
subclass of: Restriction
  on property: RO_0002202
  some values from: CL_0005003
IAO_0000115: A pigment cell derived from the neural crest. Contains uric acid or other purine crystals deposited in stacks called leucosomes. The crystals reflect light and this gives a white appearance under white light.

retinal cone cell
type: Class
subclass of: CL_0010009
subclass of: Restriction
  on property: RO_0002202
  some values from: CL_0002672
IAO_0000115: One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision.
has related synonym: cone

erythrophore
type: Class
subclass of: BFO_0000002
subclass of: pigment cell
subclass of: Restriction
  on property: RO_0002202
  some values from: CL_0005004
IAO_0000115: A pigment cell derived from the neural crest. Contains pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives an orange to red appearance.

corneal epithelial cell
type: Class
equivalent class: Class
  intersection of: squamous epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001772
subclass of: squamous epithelial cell
subclass of: general ecto-epithelial cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001772
IAO_0000115: An epithelial cell of the cornea.
has exact synonym: epithelial cell of cornea

monocyte
type: Class
equivalent class: Class
  intersection of: myeloid leukocyte
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001407
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030225
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030316
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0043011
subclass of: mononuclear phagocyte
subclass of: myeloid leukocyte
subclass of: CL_0011026
subclass of: Restriction
  on property: RO_0002202
  some values from: promonocyte
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030225
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030316
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0043011
IAO_0000115: Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells.

border follicle cell
type: Class
subclass of: follicle cell of egg chamber
IAO_0000115: A follicle cell that migrates from the anterior pole of the insect egg chamber to the anterior of the oocyte where they participate in the formation of the micropyle.

enterocyte
type: Class
subclass of: brush border epithelial cell
subclass of: gut absorptive cell
subclass of: CL_0002563
IAO_0000115: An epithelial cell that has its apical plasma membrane folded into microvilli to provide ample surface for the absorption of nutrients from the intestinal lumen.
has narrow synonym: differentiated enterocyte
has narrow synonym: mature enterocyte

germ cell
type: Class
subclass of: germ line cell
subclass of: Restriction
  on property: RO_0002216
  some values from: GO_0009566
IAO_0000115: The reproductive cell in multicellular organisms.

odontoclast
type: Class
equivalent class: Class
  intersection of: osteoclast
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0042483
subclass of: osteoclast
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0042483
IAO_0000115: A specialized osteoclast associated with the absorption and removal of cementum.

androgen secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0035935
subclass of: steroid hormone secreting cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0035935
IAO_0000115: A steroid hormone secreting cell that secretes androgen.

skeletal muscle satellite cell
type: Class
subclass of: cell of skeletal muscle
subclass of: muscle precursor cell
IAO_0000115: An elongated, spindle-shaped, cell that is located between the basal lamina and the plasmalemma of a muscle fiber. These cells are mostly quiescent, but upon activation they divide to produce cells that generate new muscle fibers.

enucleate erythrocyte
type: Class
equivalent class: Class
  intersection of: erythrocyte
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001405
subclass of: anucleate cell
subclass of: erythrocyte
subclass of: Restriction
  on property: RO_0002202
  some values from: enucleated reticulocyte
IAO_0000115: An erythrocyte lacking a nucleus.
has broad synonym: red blood cell
has related synonym: RBC

sexual spore
type: Class
subclass of: fungal spore
IAO_0000115: A spore formed following meiosis. Sometimes following meiosis, prospores may undergo one or more rounds of mitosis before they are fully mature.
has exact synonym: meiotically-derived spore

pyramidal neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0070015
subclass of: multipolar neuron
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0070015
IAO_0000115: Pyramidal neurons have a pyramid-shaped soma with a single axon, a large apical dendrite and multiple basal dendrites. The apex and an apical dendrite typically point toward the pial surface and other dendrites and an axon emerging from the base. The axons may have local collaterals but also project outside their region. Pyramidal neurons are found in the cerebral cortex, the hippocampus, and the amygdala.
has exact synonym: projection neuron
has exact synonym: pyramidal cell

conidium
type: Class
subclass of: fungal asexual spore
IAO_0000115: An asexual, nonmotile spore formed by higher fungi; conidia are usually made from the side or tip of specialized sporogenous cells and do not form by progressive cleavage of the cytoplasm.

cochlear outer hair cell
type: Class
subclass of: CL_4023120
IAO_0000115: A mechanoreceptor in the organ of Corti. In mammals the outer hair cells are arranged in three rows which are further from the modiolus than the single row of inner hair cells. The motile properties of the outer hair cells may contribute actively to tuning the sensitivity and frequency selectivity of the cochlea.

retinal rod cell
type: Class
subclass of: CL_0010009
subclass of: Restriction
  on property: RO_0002202
  some values from: CL_0002672
IAO_0000115: One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision.
has related synonym: rod

fungal asexual spore
type: Class
subclass of: fungal spore
IAO_0000115: A spore formed following mitosis or mitoses.

macroconidium
type: Class
subclass of: conidium
IAO_0000115: The larger of two types of asexual spores formed by some fungi; usually round or oblong.

ascospore
type: Class
subclass of: sexual spore
IAO_0000115: A thick walled spore that stores and protects one or more nuclei following sexual reproduction in an Ascomycete.

zygospore
type: Class
subclass of: sexual spore
IAO_0000115: A thick walled, sexual, resting spore formed by Zygomycetes; sometimes refers to the spore and the multi-layered cell wall that encloses the spore, the zygosporangium.

vestibular hair cell
type: Class
subclass of: ear hair cell
IAO_0000115: A mechanoreceptor located in the acoustic maculae and the semicircular canals that mediates the sense of balance, movement, and head position. The vestibular hair cells are connected to accessory structures in such a way that movements of the head displace their stereocilia. This influences the membrane potential of the cells which relay information about movements via the vestibular part of the vestibulocochlear nerve to the brain stem.
has exact synonym: vestibular receptor cell

eosinophil progenitor cell
type: Class
equivalent class: Class
  intersection of: granulocytopoietic cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000001944
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000005307
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000007857
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002981
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001003
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001408
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001865
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001867
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002065
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030222
subclass of: myeloid cell
subclass of: granulocytopoietic cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000001944
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000005307
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000007857
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002981
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001003
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001408
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001865
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001867
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002065
subclass of: Restriction
  on property: RO_0002202
  some values from: granulocyte monocyte progenitor cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030222
IAO_0000115: Any granulocytopoietic cell that has part some transcription factor PU.1 and has part some CCAAT/enhancer-binding protein alpha and has part some erythroid transcription factor and lacks plasma membrane part some CD19 molecule and lacks plasma membrane part some CD4 molecule and lacks plasma membrane part some integrin alpha-M and lacks plasma membrane part some CD3 epsilon and lacks plasma membrane part some neural cell adhesion molecule 1 and lacks plasma membrane part some CD2 molecule and lacks plasma membrane part some T-cell surface glycoprotein CD8 alpha chain and lacks plasma membrane part some membrane-spanning 4-domains subfamily A member 1 and lacks plasma membrane part some T-cell surface glycoprotein CD5 and lacks plasma membrane part some CD14 molecule and lacks plasma membrane part some lymphocyte antigen 6G and lacks plasma membrane part some lymphocyte antigen 76 (mouse) and has plasma membrane part some CD34 molecule and has plasma membrane part some ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 and has plasma membrane part some interleukin-3 receptor class 2 alpha chain and has plasma membrane part some interleukin-5 receptor subunit alpha and has plasma membrane part some mast/stem cell growth factor receptor and is capable of some eosinophil differentiation.
has related synonym: CFU-Eo
has related synonym: EoP
has related synonym: colony forming unit eosinophil
has related synonym: eosinophil stem cell

eosinophilic myelocyte
type: Class
equivalent class: Class
  intersection of: immature eosinophil
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0042582
  intersection of: Restriction
    on property: lacks_part
    some values from: GO_0070820
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001483
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001012
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001456
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001892
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001932
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002031
subclass of: immature eosinophil
subclass of: nongranular leukocyte
subclass of: myelocyte
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0042582
subclass of: Restriction
  on property: lacks_part
  some values from: GO_0070820
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001483
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001456
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001892
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001932
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002031
IAO_0000115: A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte;in this stage, production of primary granules is complete and eosinophil-specific granules has started. No nucleolus is present. These cells are integrin alpha-M-positive, CD13-positive, CD15-positive, CD16-negative, CD24-positive, and CD33-positive.

basophil progenitor cell
type: Class
equivalent class: Class
  intersection of: granulocytopoietic cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000005307
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000007857
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000007858
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002065
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002981
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030221
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000007431
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000016401
subclass of: myeloid cell
subclass of: granulocytopoietic cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000005307
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000007857
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000007858
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002065
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002981
subclass of: Restriction
  on property: RO_0002202
  some values from: basophil mast progenitor cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030221
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000007431
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000016401
IAO_0000115: A progenitor cell committed to the basophil lineage. This cell lacks hematopoietic lineage markers (lin-negative) and is CD34-positive, T1/ST2-low, CD117-negative, and FceRIa-high. This cell also expresses Gata-1, Gata-2 and C/EBPa.
has exact synonym: BaP
has related synonym: CFU-Bas
has related synonym: basophilic stem cell
has related synonym: colony forming unit basophil

basophilic myelocyte
type: Class
equivalent class: Class
  intersection of: immature basophil
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0042582
  intersection of: Restriction
    on property: lacks_part
    some values from: GO_0005730
  intersection of: Restriction
    on property: lacks_part
    some values from: GO_0070820
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001483
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001012
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001456
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001892
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001932
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002031
subclass of: immature basophil
subclass of: nongranular leukocyte
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0042582
subclass of: Restriction
  on property: lacks_part
  some values from: GO_0005730
subclass of: Restriction
  on property: lacks_part
  some values from: GO_0070820
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001483
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001456
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001892
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001932
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002031
IAO_0000115: A basophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte; in this stage, production of primary granules is complete and basophil-specific granules has started. No nucleolus is present. Markers are being integrin alpha-M-positive, fucosyltransferase FUT4-positive, CD33-positive, CD24-positive, aminopeptidase N-positive.

basidiospore
type: Class
subclass of: sexual spore
IAO_0000115: A thick walled spore containing one or more haploid nuclei produced by sexual reproduction in an Basidiomycete; formed externally on extrusions of the basidium.

GABAergic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0061534
subclass of: secretory cell
subclass of: neuron
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0061534
IAO_0000115: A neuron that uses GABA as a vesicular neurotransmitter
has exact synonym: GABA-ergic neuron

acinar cell
type: Class
subclass of: glandular epithelial cell
subclass of: protein secreting cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0009842
IAO_0000115: A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus).
has exact synonym: acinic cell
has exact synonym: acinous cell

natural killer cell
type: Class
equivalent class: Class
  intersection of: group 1 innate lymphoid cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002228
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0050776
subclass of: group 1 innate lymphoid cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: RO_0002202
  some values from: pro-NK cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002228
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0050776
IAO_0000115: A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells.
has broad synonym: large granular lymphocyte
has broad synonym: null cell
has exact synonym: NK cell

CD4-positive, alpha-beta T cell
type: Class
equivalent class: Class
  intersection of: mature alpha-beta T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000025402
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001004
subclass of: mature alpha-beta T cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000025402
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001004
disjoint with: CD8-positive, alpha-beta T cell
IAO_0000115: A mature alpha-beta T cell that expresses an alpha-beta T cell receptor and the CD4 coreceptor.
has exact synonym: CD4-positive, alpha-beta T lymphocyte
has exact synonym: CD4-positive, alpha-beta T-cell
has exact synonym: CD4-positive, alpha-beta T-lymphocyte

CD8-positive, alpha-beta T cell
type: Class
equivalent class: Class
  intersection of: mature alpha-beta T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000025402
subclass of: mature alpha-beta T cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000025402
IAO_0000115: A T cell expressing an alpha-beta T cell receptor and the CD8 coreceptor.
has exact synonym: CD8-positive, alpha-beta T lymphocyte
has exact synonym: CD8-positive, alpha-beta T-cell
has exact synonym: CD8-positive, alpha-beta T-lymphocyte

supporting cell
type: Class
subclass of: cell
IAO_0000115: A cell whose primary function is to support other cell types.
has exact synonym: supportive cell

hepatic stellate cell
type: Class
equivalent class: Class
  intersection of: connective tissue cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002107
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000007939
subclass of: fibroblast
subclass of: extracellular matrix secreting cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002107
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000007939
IAO_0000115: A cell that is found in the perisinusoidal space of the liver that is capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components that can contribute to liver fibrosis. This activated state has a myofibroblast-like phenotype, though it's not clear in the literature if this is terminally differentiated. This cell type comprises approximately 8-15% of total cells in the liver.
has exact synonym: Ito cell
has exact synonym: hepatic perisinusoidal cell
has exact synonym: perisinusoidal cell
has related synonym: fat-storing cell
has related synonym: lipocyte
has related synonym: vitamin A-storing cells

chromophil cell of anterior pituitary gland
type: Class
equivalent class: Class
  intersection of: chromaffin cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002196
subclass of: glandular epithelial cell
subclass of: chromaffin cell
subclass of: peptide hormone secreting cell
subclass of: CL_2000004
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002196
IAO_0000115: A cell that stains readily in the anterior pituitary gland.

basophil cell of pars distalis of adenohypophysis
type: Class
subclass of: chromophil cell of anterior pituitary gland
IAO_0000115: A basophilic chromophil cell that of the anterior pituitary gland.
has exact synonym: basophil cell of anterior lobe of hypophysis
has related synonym: beta cell
has related synonym: pituitary beta cell

Bergmann glial cell
type: Class
subclass of: astrocyte
IAO_0000115: Type of radial astrocyte in the cerebellar cortex that have their cell bodies in the Purkinje cell layer and processes that extend into the molecular layer, terminating with bulbous endfeet at the pial surface. Bergmann glia express high densities of glutamate transporters that limit diffusion of the neurotransmitter glutamate during its release from synaptic terminals. Besides their role in early development of the cerebellum, Bergmann glia are also required for the pruning or addition of synapses.
has exact synonym: Bergmann astrocyte
has exact synonym: Bergmann glial cell of cerebellum

basal cell
type: Class
subclass of: epithelial fate stem cell
IAO_0000115: Undifferentiated; mitotic stem cell for other epithelial cell types; rounded or elliptical with little cytoplasm and few organelles; contain cytokeratin intermediate filament.

multinucleated giant cell
type: Class
equivalent class: Class
  intersection of: myeloid leukocyte
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001908
  intersection of: Restriction
    on property: RO_0000056
    some values from: GO_0002432
  intersection of: Restriction
    on property: RO_0000056
    some values from: GO_0002544
subclass of: multinucleate cell
subclass of: myeloid leukocyte
subclass of: Restriction
  on property: RO_0000056
  some values from: GO_0002432
subclass of: Restriction
  on property: RO_0000056
  some values from: GO_0002544
subclass of: Restriction
  on property: RO_0002202
  some values from: macrophage
IAO_0000115: A phagocytic cell formed by the fusion of macrophages, occurs in chronic inflammatory responses to persistent microorganism such as M.tuberculosis, component of granulomas. Sometimes used to refer to megakaryocytes.
has exact synonym: Langerhans giant cell
has exact synonym: foreign body giant cell
has exact synonym: macrophage polykaryon
has exact synonym: multinucleate giant cell
has exact synonym: syncytial giant cell

kidney granular cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002113
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002001
subclass of: protein secreting cell
subclass of: smooth muscle cell
subclass of: CL_1000618
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002001
IAO_0000115: A smooth muscle cell that synthesizes, stores, and secretes the enzyme renin. This cell type are located in the wall of the afferent arteriole at the entrance to the glomerulus. While having a different origin than other kidney smooth muscle cells, this cell type expresses smooth muscle actin upon maturation.
has broad synonym: juxtaglomerular cell
has exact synonym: JG cell
has exact synonym: renin secreting cell

mesangial cell
type: Class
subclass of: BFO_0000002
subclass of: pericyte
subclass of: Restriction
  on property: RO_0002202
  some values from: mesenchymal stem cell
IAO_0000115: A cell type that encapsulates the capillaries and venules in the kidney. This cell secretes mesangial matrix that provides the structural support for the capillaries.
has exact synonym: kidney mesangial cell

podocyte
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0005751
subclass of: renal filtration cell
subclass of: CL_1000450
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0005751
IAO_0000115: A specialized kidney epithelial cell, contained within a glomerulus, that contains "feet" that interdigitate with the "feet" of other podocytes.
has broad synonym: epithelial cell of visceral layer of glomerular capsule
has exact synonym: glomerular podocyte
has exact synonym: glomerular visceral epithelial cell
has exact synonym: kidney podocyte
has exact synonym: renal podocyte

primary oocyte
type: Class
equivalent class: Class
  intersection of: oocyte
  intersection of: Restriction
    on property: has_not_completed
    some values from: GO_0051321
subclass of: oocyte
subclass of: Restriction
  on property: has_not_completed
  some values from: GO_0051321
subclass of: Restriction
  on property: RO_0002202
  some values from: oogonial cell
IAO_0000115: A primary oocyte is an oocyte that has not completed female meosis I.
has related synonym: primary oogonium

secondary oocyte
type: Class
equivalent class: Class
  intersection of: oocyte
  intersection of: Restriction
    on property: has_not_completed
    some values from: GO_0007147
subclass of: oocyte
subclass of: Restriction
  on property: has_not_completed
  some values from: GO_0007147
subclass of: Restriction
  on property: RO_0002202
  some values from: primary oocyte
IAO_0000115: A secondary oocyte is an oocyte that has not completed meiosis II.
has related synonym: primary oogonium

primary spermatocyte
type: Class
equivalent class: Class
  intersection of: spermatocyte
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001394
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0007140
subclass of: spermatocyte
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0001394
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0007140
IAO_0000115: A diploid cell that has derived from a spermatogonium and can subsequently begin meiosis and divide into two haploid secondary spermatocytes.

secondary spermatocyte
type: Class
equivalent class: Class
  intersection of: spermatocyte
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001375
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0007142
subclass of: spermatocyte
subclass of: haploid cell
subclass of: Restriction
  on property: RO_0002202
  some values from: primary spermatocyte
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0007142
IAO_0000115: One of the two haploid cells into which a primary spermatocyte divides, and which in turn gives origin to spermatids.

distal tip cell (sensu Nematoda)
type: Class
subclass of: mitogenic signaling cell

fenestrated endothelial cell
type: Class
equivalent class: Class
  intersection of: endothelial cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0002064
subclass of: endothelial cell
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0002064
IAO_0000115: An endothelial cell that has small pores, or fenestrations, which allow for the efficient exchange of substances between the blood and surrounding tissues.
has exact synonym: window cell

collagen secreting cell
type: Class
subclass of: extracellular matrix secreting cell
IAO_0000115: An extracellular matrix secreting cell that secretes collagen.

pericyte
type: Class
subclass of: contractile cell
subclass of: supporting cell
subclass of: connective tissue cell
subclass of: CL_0008034
IAO_0000115: An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells.
has exact synonym: ARC
has exact synonym: adventitial reticular cell
has exact synonym: cell of Rouget
has exact synonym: pericyte cell
has exact synonym: pericyte of Rouget
has related synonym: adventitial cell

primordial germ cell
type: Class
equivalent class: Class
  intersection of: germ line cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000922
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0048870
subclass of: germ line cell
subclass of: motile cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000922
IAO_0000115: A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells.
has exact synonym: gonocyte
has exact synonym: primitive germ cell

centripetally migrating follicle cell
type: Class
subclass of: follicle cell of egg chamber
IAO_0000115: A follicle cell that migrates from the dorso-anterior part of the oocyte associated follicular epithelium, in between the nurse cells and the oocyte, and participates in the formation of the operculum.
has exact synonym: centripetal follicle cell

female gamete
type: Class
subclass of: female germ cell
subclass of: gamete
IAO_0000115: A mature sexual reproductive cell of the female germline.

gut absorptive cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001277
IAO_0000115: Cell of the intestinal epithelium with a brush border made up of many parallel packed microvilli; associated with absorption, particularly of macromolecules.

commissural neuron
type: Class
subclass of: neuron

glutamatergic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0061535
subclass of: secretory cell
subclass of: neuron
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0061535
IAO_0000115: A neuron that is capable of some neurotansmission by glutamate secretion.

muscle precursor cell
type: Class
equivalent class: Class
  intersection of: CL_0011115
  intersection of: Restriction
    on property: RO_0002203
    some values from: muscle cell
subclass of: BFO_0000002
subclass of: non-terminally differentiated cell
subclass of: Restriction
  on property: RO_0002202
  some values from: mesodermal cell
subclass of: Restriction
  on property: RO_0002203
  some values from: muscle cell
IAO_0000115: A non-terminally differentiated cell that is capable of developing into a muscle cell.

radial glial cell
type: Class
subclass of: glial cell
subclass of: Restriction
  on property: RO_0002202
  some values from: neurecto-epithelial cell
IAO_0000115: A cell present in the developing CNS. Functions as both a precursor cell and as a scaffold to support neuronal migration.
has narrow synonym: forebrain radial glial cell

ependymoglial cell
type: Class
subclass of: astrocyte
IAO_0000115: A cell that transports hormones from neurosecretory cells. This nerve cell is characterized by bipolar shape and endfeet that contact a basal lamina around blood vessels, and/or the pia mater or vitreous body of the eye and additionally contact the ventricular surface or sub-retinal space.
has exact synonym: ependymal astrocyte

cerebrospinal fluid secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0033326
subclass of: secretory cell
subclass of: neurecto-epithelial cell
subclass of: Restriction
  on property: RO_0002202
  some values from: migratory neural crest cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0033326
IAO_0000115: A columnar/cuboidal epithelial cell that secretes cerebrospinal fluid.

stellate interneuron
type: Class
equivalent class: Class
  intersection of: interneuron
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0070010
subclass of: interneuron
subclass of: multipolar neuron
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0070010
IAO_0000115: Any interneuron that has characteristic some stellate morphology.

Cajal-Retzius cell
type: Class
subclass of: CNS neuron (sensu Vertebrata)
subclass of: CL_2000029
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0070006
subclass of: Restriction
  on property: RO_0002100
  some values from: UBERON_0010403
IAO_0000115: A neuron of the human embryonic marginal zone which display, as a salient feature, radial ascending processes that contact the pial surface, and a horizontal axon plexus located in the deep marginal zone. One feature of these cells in mammals is that they express the Reelin gene.
has exact synonym: CR cells
has exact synonym: Horizontal cells of Cajal

PP cell
type: Class
subclass of: enteroendocrine cell
subclass of: peptide hormone secreting cell
IAO_0000115: A cell that stores and secretes pancreatic polypeptide hormone.
has exact synonym: type F enteroendocrine cell

dopaminergic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0061527
subclass of: CL_4033050
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0061527
IAO_0000115: A neuron that releases dopamine as a neurotransmitter.
has exact synonym: dopaminergic cell

endothelial tip cell
type: Class
subclass of: blood vessel endothelial cell
IAO_0000115: A specialized endothelial cell that senses extracellular signals and guides the directed growth of blood vessels.

R7 photoreceptor cell
type: Class
subclass of: UV sensitive photoreceptor cell
subclass of: CL_2000019
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000971
has exact synonym: R7 cell

leptomeningeal cell
type: Class
equivalent class: Class
  intersection of: extracellular matrix secreting cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0003210
subclass of: extracellular matrix secreting cell
subclass of: neural cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0003210
IAO_0000115: Stromal cell that forms the internal covering of the vertebrate brain and produces ECM for this and the choroid plexus.
has related synonym: leptomemingeal cell

R8 photoreceptor cell
type: Class
subclass of: visible light photoreceptor cell
subclass of: CL_2000019
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000971
has exact synonym: R8 cell

neurecto-epithelial cell
type: Class
equivalent class: Class
  intersection of: ecto-epithelial cell
  intersection of: Restriction
    on property: RO_0002202
    some values from: neurectodermal cell
subclass of: columnar/cuboidal epithelial cell
subclass of: ecto-epithelial cell
subclass of: Restriction
  on property: RO_0002202
  some values from: neurectodermal cell
IAO_0000115: Epithelial cells derived from neural plate and neural crest.
has broad synonym: neuroepithelial cell

cumulus cell
type: Class
subclass of: protein secreting cell
subclass of: follicular cell of ovary
subclass of: Restriction
  on property: RO_0002202
  some values from: granulosa cell
IAO_0000115: Cumulus cell is a specialized granulosa cell that surrounds and nourishes the oocyte. This cell-type surrounds the fully-grown oocyte to form a cumulus-oocyte complex (abbr. COC). The terms cumulus oophorus cells, cumulus granulosa cells, cumulus oophorous granulosa cells, granulosa-cumulus cells are used to make a distinction between this cell and the other functionally different subpopulation of granulosa cells at the wall of the Graafian follicle.

embryonic crystal cell
type: Class
subclass of: crystal cell
subclass of: CL_0011008
IAO_0000115: A crystal cell that derives from the embryonic head mesoderm.

lymph gland crystal cell
type: Class
subclass of: crystal cell
subclass of: lymph gland hemocyte
IAO_0000115: A crystal cell that derives from the larval lymph gland.

compound eye cone cell
type: Class
subclass of: crystallin accumulating cell
subclass of: neural cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000971
IAO_0000115: A cell of an ommatidium that secretes lens materials.
has exact synonym: Semper cell
has related synonym: cone cell (sensu Endopterygota)

cystoblast
type: Class
subclass of: eukaryotic cell
subclass of: germ cell
subclass of: Restriction
  on property: RO_0002160
  some values from: NCBITaxon 6656

somatic stem cell
type: Class
equivalent class: Class
  intersection of: stem cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0048103
subclass of: stem cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0048103
IAO_0000115: A stem cell that can give rise to cell types of the body other than those of the germ-line.

heterocyst
type: Class
subclass of: prokaryotic cell
subclass of: nitrogen fixing cell
IAO_0000115: A differentiated cell that functions as a site of nitrogen fixation under aerobic conditions.

nitrogen fixing cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0009399
subclass of: cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0009399
IAO_0000115: Any cell that is capable of some nitrogen fixation.

chlamydospore
type: Class
subclass of: fungal asexual spore
IAO_0000115: An asexual 1-celled spore (primarily for perennation, not dissemination). Originates endogenously and singly within part of a pre-existing cell by the contraction of the protoplast. Possesses an inner secondary and often thickened hyaline or brown wall, usually impregnated with hydrophobic material.

leading edge cell
type: Class
subclass of: epithelial cell
IAO_0000115: A cell at the front of a migrating epithelial sheet.

urothelial cell
type: Class
equivalent class: Class
  intersection of: transitional epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000365
subclass of: transitional epithelial cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000365
IAO_0000115: A cell of a layer of transitional epithelium in the wall of the proximal urethra, bladder, ureter or renal pelvis, external to the lamina propria.
has narrow synonym: urinary tract transitional epithelial cell

lymph gland plasmatocyte
type: Class
subclass of: plasmatocyte
subclass of: lymph gland hemocyte
IAO_0000115: A plasmatocyte that derives from the larval lymph gland.

lymph gland hemocyte
type: Class
subclass of: hemocyte (sensu Arthropoda)
IAO_0000115: A hemocyte that derives from the larval lymph gland.

striated muscle cell
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0030017
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001410
subclass of: muscle cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0030017
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0001410
disjoint with: CL_0008000
IAO_0000115: Muscle cell which has as its direct parts myofilaments organized into sarcomeres.

leukocyte
type: Class
equivalent class: Class
  intersection of: hematopoietic cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0002505
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0001667
subclass of: BFO_0000002
subclass of: motile cell
subclass of: eukaryotic cell
subclass of: hematopoietic cell
subclass of: nucleate cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002405
subclass of: Restriction
  on property: RO_0002160
  some values from: NCBITaxon 7742
subclass of: Restriction
  on property: RO_0002202
  some values from: hematopoietic stem cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0001667
IAO_0000115: An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
has exact synonym: leucocyte
has exact synonym: white blood cell
has related synonym: immune cell

retinal ganglion cell
type: Class
subclass of: CNS neuron (sensu Vertebrata)
subclass of: Restriction
  on property: RO_0002100
  some values from: UBERON_0000966
IAO_0000115: The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve.
has exact synonym: gangliocyte
has exact synonym: ganglion cell of retina
has related synonym: RGC
has related synonym: RGCs

cardiac muscle cell
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0007100
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0030017
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0002478
  intersection of: Restriction
    on property: RO_0000056
    some values from: GO_0060047
subclass of: striated muscle cell
subclass of: cardiocyte
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0002478
subclass of: Restriction
  on property: RO_0000056
  some values from: GO_0060047
subclass of: Restriction
  on property: RO_0002202
  some values from: cardiac muscle myoblast
IAO_0000115: Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei.
has broad synonym: cardiocyte
has exact synonym: cardiac muscle fiber
has exact synonym: cardiac myocyte
has exact synonym: cardiomyocyte
has exact synonym: heart muscle cell

cyanophore
type: Class
subclass of: BFO_0000002
subclass of: pigment cell
subclass of: Restriction
  on property: RO_0002202
  some values from: CL_0005005
IAO_0000115: A pigment cell derived from the neural crest. Contains blue pigment of unknown chemical composition in fibrous organelles termed cyanosomes. This gives a blue appearance.
has related synonym: blue chromatophore

retinal bipolar neuron
type: Class
equivalent class: Class
  intersection of: bipolar neuron
  intersection of: Restriction
    on property: RO_0002100
    some values from: UBERON_0001791
subclass of: bipolar neuron
subclass of: glutamatergic neuron
subclass of: CL_0008028
subclass of: CL_0009004
subclass of: Restriction
  on property: RO_0002100
  some values from: UBERON_0001791
subclass of: Restriction
  on property: RO_0002215
  some values from: Class
    intersection of: GO_0061535
    intersection of: Restriction
      on property: BFO_0000050
      some values from: GO_0098976
IAO_0000115: A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner plexiform layer.
has related synonym: BC
has related synonym: BCs
has related synonym: BPs

ON-bipolar cell
type: Class
subclass of: retinal bipolar neuron
IAO_0000115: A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner half of the inner plexiform layer. These cells depolarize in response to light stimulation of their corresponding photoreceptors.

rod bipolar cell
type: Class
subclass of: BFO_0000002
subclass of: eukaryotic cell
subclass of: ON-bipolar cell
subclass of: Restriction
  on property: RO_0002102
  some values from: UBERON_0008925
subclass of: Restriction
  on property: RO_0002102
  some values from: UBERON_0008926
subclass of: Restriction
  on property: RO_0002103
  some values from: retinal rod cell
subclass of: Restriction
  on property: RO_0002160
  some values from: NCBITaxon_40674
IAO_0000115: A bipolar neuron found in the retina that is synapsed by rod photoreceptor cells but not by cone photoreceptor cells. These neurons depolarize in response to light.

cone retinal bipolar cell
type: Class
equivalent class: Class
  intersection of: retinal bipolar neuron
  intersection of: Restriction
    on property: RO_0002103
    some values from: retinal cone cell
subclass of: retinal bipolar neuron
subclass of: Restriction
  on property: RO_0002103
  some values from: retinal cone cell
IAO_0000115: A bipolar neuron found in the retina and having connections with cone photoreceptor cells and neurons in the inner plexiform layer.

nucleated thrombocyte
type: Class
equivalent class: Class
  intersection of: myeloid cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001407
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0007596
subclass of: single nucleate cell
subclass of: myeloid cell
subclass of: Restriction
  on property: RO_0002202
  some values from: thromboblast
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0007596
IAO_0000115: A nucleated blood cell involved in coagulation, typically seen in birds and other non-mammalian vertebrates.

myeloid cell
type: Class
equivalent class: Class
  intersection of: hematopoietic cell
  intersection of: Restriction
    on property: RO_0002202
    some values from: common myeloid progenitor
subclass of: BFO_0000002
subclass of: hematopoietic cell
subclass of: Restriction
  on property: RO_0002202
  some values from: common myeloid progenitor
IAO_0000115: A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.

erythroid lineage cell
type: Class
subclass of: myeloid cell
IAO_0000115: A immature or mature cell in the lineage leading to and including erythrocytes.
has exact synonym: erythropoietic cell

erythroblast
type: Class
equivalent class: Class
  intersection of: erythroid lineage cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0005634
  intersection of: Restriction
    on property: lacks_part
    some values from: GO_0005730
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030218
subclass of: erythroid lineage cell
subclass of: CL_0011026
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0005634
subclass of: Restriction
  on property: lacks_part
  some values from: GO_0005730
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: RO_0002202
  some values from: proerythroblast
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030218
IAO_0000115: A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers.
has exact synonym: normoblast

myeloid leukocyte
type: Class
equivalent class: Class
  intersection of: leukocyte
  intersection of: Restriction
    on property: RO_0002202
    some values from: common myeloid progenitor
subclass of: leukocyte
subclass of: myeloid cell
IAO_0000115: A cell of the monocyte, granulocyte, or mast cell lineage.

basophil
type: Class
equivalent class: Class
  intersection of: granulocyte
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001344
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001950
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001255
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001865
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000007431
subclass of: granulocyte
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001344
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001950
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001255
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001865
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000007431
IAO_0000115: Any of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. A basophil is CD123-positive, CD193-positive, CD203c-positive, and FceRIa-positive.
has broad synonym: polymorphonuclear leucocyte
has broad synonym: polymorphonuclear leukocyte
has exact synonym: basophilic leucocyte
has exact synonym: basophilic leukocyte

immature basophil
type: Class
equivalent class: Class
  intersection of: basophil
  intersection of: Restriction
    on property: BFO_0000051
    some values from: CL_0017509
subclass of: basophil
subclass of: Restriction
  on property: BFO_0000051
  some values from: CL_0017509
subclass of: Restriction
  on property: RO_0002202
  some values from: basophilic promyelocyte
IAO_0000115: Any of the immature forms of a basophil, in which basophilic specific granules are present but other phenotypic features of the mature form may be lacking.
has exact synonym: immature basophilic leucocyte
has exact synonym: immature basophilic leukocyte

basophilic metamyelocyte
type: Class
equivalent class: Class
  intersection of: immature basophil
  intersection of: Restriction
    on property: BFO_0000051
    some values from: CL_0017507
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0000792
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0042582
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0070820
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001012
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001456
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001483
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001892
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001932
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002031
subclass of: immature basophil
subclass of: metamyelocyte
subclass of: Restriction
  on property: BFO_0000051
  some values from: CL_0017507
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0000792
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0042582
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0070820
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001456
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001483
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001892
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001932
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002031
subclass of: Restriction
  on property: RO_0002202
  some values from: basophilic myelocyte
IAO_0000115: A basophil precursor in the granulocytic series, being a cell intermediate in development between a basophilic myelocyte and a band form basophil. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. Markers are CD11b-positive, CD15-positive, CD16-positive, CD24-positive, CD33-positive, and CD13-positive.

band form basophil
type: Class
equivalent class: Class
  intersection of: immature basophil
  intersection of: Restriction
    on property: BFO_0000051
    some values from: CL_0017506
subclass of: immature basophil
subclass of: Restriction
  on property: BFO_0000051
  some values from: CL_0017506
subclass of: Restriction
  on property: RO_0002202
  some values from: basophilic metamyelocyte
IAO_0000115: A late basophilic metamyelocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature basophil.

eosinophil
type: Class
equivalent class: Class
  intersection of: granulocyte
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001254
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001255
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001307
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001343
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000005178
subclass of: granulocyte
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001254
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001255
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001307
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001343
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000005178
IAO_0000115: Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive.
has broad synonym: polymorphonuclear leucocyte
has broad synonym: polymorphonuclear leukocyte
has exact synonym: eosinocyte
has exact synonym: eosinophilic granulocyte
has exact synonym: eosinophilic leucocyte
has exact synonym: eosinophilic leukocyte

immature eosinophil
type: Class
equivalent class: Class
  intersection of: eosinophil
  intersection of: Restriction
    on property: BFO_0000051
    some values from: CL_0017509
subclass of: eosinophil
subclass of: Restriction
  on property: BFO_0000051
  some values from: CL_0017509
subclass of: Restriction
  on property: RO_0002202
  some values from: eosinophilic promyelocyte
IAO_0000115: Any of the immature forms of an eosinophil, in which eosinophilic specific granules are present but other phenotypic features of the mature form may be lacking.
has exact synonym: immature eosinocyte
has exact synonym: immature eosinophilic leucocyte
has exact synonym: immature eosinophilic leukocyte

eosinophilic metamyelocyte
type: Class
equivalent class: Class
  intersection of: immature eosinophil
  intersection of: Restriction
    on property: BFO_0000051
    some values from: CL_0017502
  intersection of: Restriction
    on property: BFO_0000051
    some values from: CL_0017507
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0000792
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0042582
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0070820
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001012
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001456
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001483
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001892
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001932
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002031
subclass of: immature eosinophil
subclass of: metamyelocyte
subclass of: Restriction
  on property: BFO_0000051
  some values from: CL_0017502
subclass of: Restriction
  on property: BFO_0000051
  some values from: CL_0017507
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0000792
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0042582
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0070820
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001456
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001483
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001892
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001932
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002031
subclass of: Restriction
  on property: RO_0002202
  some values from: eosinophilic myelocyte
IAO_0000115: A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a eosinophilic myelocyte and a band form eosinophil. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. Markers are integrin alpha-M-positive, fucosyltransferase FUT4-positive, low affinity immunoglobulin gamma Fc region receptor III-positive, CD33-positive, CD24-positive and aminopeptidase N-negative.

band form eosinophil
type: Class
equivalent class: Class
  intersection of: immature eosinophil
  intersection of: Restriction
    on property: BFO_0000051
    some values from: CL_0017506
subclass of: immature eosinophil
subclass of: Restriction
  on property: BFO_0000051
  some values from: CL_0017506
subclass of: Restriction
  on property: RO_0002202
  some values from: eosinophilic metamyelocyte
IAO_0000115: A late eosinophilic metamyelocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature eosinophil.

neutrophil
type: Class
equivalent class: Class
  intersection of: granulocyte
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001479
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001879
subclass of: granulocyte
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001479
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001879
IAO_0000115: Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.
has broad synonym: PMN
has broad synonym: poly
has broad synonym: polymorphonuclear leucocyte
has broad synonym: polymorphonuclear leukocyte
has broad synonym: polymorphonuclear neutrophil
has broad synonym: polynuclear neutrophilic leucocyte
has broad synonym: polynuclear neutrophilic leukocyte
has exact synonym: neutrocyte
has exact synonym: neutrophil leucocyte
has exact synonym: neutrophil leukocyte
has exact synonym: neutrophilic leucocyte
has exact synonym: neutrophilic leukocyte

immature neutrophil
type: Class
equivalent class: Class
  intersection of: neutrophil
  intersection of: Restriction
    on property: BFO_0000051
    some values from: CL_0017509
subclass of: neutrophil
subclass of: Restriction
  on property: BFO_0000051
  some values from: CL_0017509
subclass of: Restriction
  on property: RO_0002202
  some values from: neutrophilic promyelocyte
IAO_0000115: Any of the immature forms of a neutrophil in which neutrophilic specific granules are present but other phenotypic features of the mature form may be lacking.
has exact synonym: immatuer neutrophilic leukocyte
has exact synonym: immature neutrocyte
has exact synonym: immature neutrophil leucocyte
has exact synonym: immature neutrophil leukocyte
has exact synonym: immature neutrophilic leucocyte

mesangial phagocyte
type: Class
equivalent class: Class
  intersection of: tissue-resident macrophage
  intersection of: Restriction
    on property: RO_0001025
    some values from: UBERON_0002320
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0019882
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0048771
subclass of: tissue-resident macrophage
subclass of: Restriction
  on property: RO_0001025
  some values from: UBERON_0002320
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0048771
IAO_0000115: A tissue-resident macrophage of the renal glomerular mesangium involved in the disposal and degradation of filtration residues, presentation of antigen to T cells and in tissue remodeling.
has broad synonym: mesangial cell

mononuclear osteoclast
type: Class
equivalent class: Class
  intersection of: osteoclast
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001407
subclass of: osteoclast
subclass of: mononuclear phagocyte
IAO_0000115: A specialized mononuclear osteoclast associated with the absorption and removal of bone, precursor of multinuclear osteoclasts.

multinuclear osteoclast
type: Class
equivalent class: Class
  intersection of: osteoclast
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001908
subclass of: osteoclast
subclass of: multinucleated phagocyte
subclass of: Restriction
  on property: RO_0002202
  some values from: mononuclear osteoclast
IAO_0000115: A specialized multinuclear osteoclast associated with the absorption and removal of bone.
has exact synonym: multinucleated osteoclast

multinuclear odontoclast
type: Class
equivalent class: Class
  intersection of: odontoclast
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001908
subclass of: odontoclast
subclass of: multinuclear osteoclast
subclass of: Restriction
  on property: RO_0002202
  some values from: mononuclear odontoclast
IAO_0000115: A specialized multinuclear osteoclast associated with the absorption and removal of cementum.
has exact synonym: multinucleated odontoclast

mononuclear odontoclast
type: Class
equivalent class: Class
  intersection of: odontoclast
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001407
subclass of: odontoclast
subclass of: mononuclear osteoclast
IAO_0000115: A specialized mononuclear osteoclast associated with the absorption and removal of cementum.

myeloid dendritic cell
type: Class
equivalent class: Class
  intersection of: conventional dendritic cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001865
  intersection of: Restriction
    on property: RO_0002202
    some values from: myeloid cell
subclass of: myeloid leukocyte
subclass of: conventional dendritic cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001865
subclass of: Restriction
  on property: RO_0002202
  some values from: myeloid cell
IAO_0000115: A dendritic cell of the myeloid lineage.
has broad synonym: interdigitating cell
has broad synonym: veiled cell
has exact synonym: CD11c+CD123- DC
has exact synonym: mDC

multinucleated phagocyte
type: Class
equivalent class: Class
  intersection of: phagocyte (sensu Vertebrata)
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001908
subclass of: multinucleate cell
subclass of: phagocyte (sensu Vertebrata)
IAO_0000115: A phagocyte formed by the fusion of mononuclear phagocytes.

plasmacytoid dendritic cell
type: Class
equivalent class: Class
  intersection of: dendritic cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032606
subclass of: dendritic cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032606
IAO_0000115: A dendritic cell type of distinct morphology, localization, and surface marker expression (CD123-positive) from other dendritic cell types and associated with early stage immune responses, particularly the release of physiologically abundant amounts of type I interferons in response to infection.
has exact synonym: DC2
has exact synonym: IPC
has exact synonym: T-associated plasma cell
has exact synonym: interferon-producing cell
has exact synonym: lymphoid dendritic cell
has exact synonym: pDC
has exact synonym: plasmacytoid T cell
has exact synonym: plasmacytoid monocyte
has exact synonym: type 2 DC

mature B cell
type: Class
equivalent class: Class
  intersection of: B cell, CD19-positive
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002504
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0042113
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0002335
subclass of: professional antigen presenting cell
subclass of: B cell, CD19-positive
subclass of: Restriction
  on property: RO_0002202
  some values from: transitional stage B cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0042113
subclass of: Restriction
  on property: RO_0002353
  some values from: GO_0002335
disjoint with: immature B cell
disjoint with: precursor B cell
disjoint with: transitional stage B cell
IAO_0000115: A B cell that is mature, having left the bone marrow. Initially, these cells are IgM-positive and IgD-positive, and they can be activated by antigen.
has exact synonym: mature B lymphocyte
has exact synonym: mature B-cell
has exact synonym: mature B-lymphocyte

plasma cell
type: Class
equivalent class: Class
  intersection of: antibody secreting cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: CL_0017508
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0005794
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0019814
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0042613
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001935
subclass of: antibody secreting cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: CL_0017508
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0005794
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0019814
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0042613
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001935
subclass of: Restriction
  on property: RO_0002202
  some values from: plasmablast
IAO_0000115: A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin.
has exact synonym: plasma B cell
has exact synonym: plasma B-cell
has exact synonym: plasmacyte
has exact synonym: plasmocyte
has related synonym: effector B cell
has related synonym: effector B-cell

memory B cell
type: Class
equivalent class: Class
  intersection of: mature B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001935
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0042613
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001289
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0002344
subclass of: mature B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001935
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0042613
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001289
subclass of: Restriction
  on property: RO_0002353
  some values from: GO_0002344
IAO_0000115: A memory B cell is a mature B cell that is long-lived, readily activated upon re-encounter of its antigenic determinant, and has been selected for expression of higher affinity immunoglobulin. This cell type has the phenotype CD19-positive, CD20-positive, MHC Class II-positive, and CD138-negative.
has exact synonym: memory B lymphocyte
has exact synonym: memory B-cell
has exact synonym: memory B-lymphocyte

naive B cell
type: Class
equivalent class: Class
  intersection of: mature B cell
  intersection of: Restriction
    on property: has_not_completed
    some values from: GO_0002344
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001963
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071738
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071753
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001289
subclass of: mature B cell
subclass of: Restriction
  on property: has_not_completed
  some values from: GO_0002344
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001963
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0071738
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0071753
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001289
IAO_0000115: A naive B cell is a mature B cell that has the phenotype surface IgD-positive, surface IgM-positive, CD20-positive, CD27-negative and that has not yet been activated by antigen in the periphery.
has exact synonym: naive B lymphocyte
has exact synonym: naive B-cell
has exact synonym: naive B-lymphocyte

alpha-beta T cell
type: Class
equivalent class: Class
  intersection of: T cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0042105
subclass of: T cell
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0042105
disjoint with: gamma-delta T cell
IAO_0000115: A T cell that expresses an alpha-beta T cell receptor complex.
has exact synonym: alpha-beta T lymphocyte
has exact synonym: alpha-beta T-cell
has exact synonym: alpha-beta T-lymphocyte

immature alpha-beta T cell
type: Class
equivalent class: Class
  intersection of: alpha-beta T cell
  intersection of: Restriction
    on property: has_not_completed
    some values from: GO_0045058
subclass of: alpha-beta T cell
subclass of: immature T cell
IAO_0000115: An alpha-beta T cell that has an immature phenotype and has not completed T cell selection.
has exact synonym: immature alpha-beta T lymphocyte
has exact synonym: immature alpha-beta T-cell
has exact synonym: immature alpha-beta T-lymphocyte

mature alpha-beta T cell
type: Class
equivalent class: Class
  intersection of: alpha-beta T cell
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0045058
subclass of: alpha-beta T cell
subclass of: mature T cell
subclass of: Restriction
  on property: RO_0002202
  some values from: immature alpha-beta T cell
IAO_0000115: A alpha-beta T cell that has a mature phenotype.
has exact synonym: mature alpha-beta T lymphocyte
has exact synonym: mature alpha-beta T-cell
has exact synonym: mature alpha-beta T-lymphocyte

CD4-positive, CD25-positive, alpha-beta regulatory T cell
type: Class
equivalent class: Class
  intersection of: CD4-positive, alpha-beta T cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001380
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0050777
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001869
subclass of: CD4-positive, alpha-beta T cell
subclass of: regulatory T cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001380
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001869
IAO_0000115: A CD4-positive, CD25-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release.
has broad synonym: Treg
has broad synonym: suppressor T cell
has broad synonym: suppressor T lymphocyte
has broad synonym: suppressor T-cell
has broad synonym: suppressor T-lymphocyte
has exact synonym: CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte
has exact synonym: CD4-positive, CD25-positive, alpha-beta regulatory T-cell
has exact synonym: CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte

CD4-positive, alpha-beta intraepithelial T cell
type: Class
equivalent class: Class
  intersection of: CD4-positive, alpha-beta T cell
  intersection of: Restriction
    on property: RO_0001025
    some values from: UBERON_0001277
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002385
subclass of: CD4-positive, alpha-beta T cell
subclass of: alpha-beta intraepithelial T cell
subclass of: Restriction
  on property: RO_0002202
  some values from: CD4-positive, alpha-beta thymocyte
IAO_0000115: A CD4-positive, alpha-beta T cell that is found in the columnar epithelium of the gastrointestinal tract.
has broad synonym: IEL
has broad synonym: intraepithelial lymphocyte
has exact synonym: CD4-positive, alpha-beta intraepithelial T lymphocyte
has exact synonym: CD4-positive, alpha-beta intraepithelial T-cell
has exact synonym: CD4-positive, alpha-beta intraepithelial T-lymphocyte

CD8-positive, alpha-beta cytotoxic T cell
type: Class
equivalent class: Class
  intersection of: CD8-positive, alpha-beta T cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000003466
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000003499
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0001913
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0033380
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0030217
subclass of: CD8-positive, alpha-beta T cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000003466
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000003499
subclass of: Restriction
  on property: RO_0002202
  some values from: activated CD8-positive, alpha-beta T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0001913
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0033380
subclass of: Restriction
  on property: RO_0002353
  some values from: GO_0030217
IAO_0000115: A CD8-positive, alpha-beta T cell that is capable of killing target cells in an antigen specific manner with the phenotype perforin-positive and granzyme B-positive.
has broad synonym: cytotoxic T cell
has broad synonym: cytotoxic T lymphocyte
has broad synonym: cytotoxic T-cell
has broad synonym: cytotoxic T-lymphocyte
has broad synonym: killer T cell
has broad synonym: killer T lymphocyte
has broad synonym: killer T-cell
has broad synonym: killer T-lymphocyte
has exact synonym: CD8-positive, alpha-beta cytotoxic T lymphocyte
has exact synonym: CD8-positive, alpha-beta cytotoxic T-cell
has exact synonym: CD8-positive, alpha-beta cytotoxic T-lymphocyte

CD8-positive, alpha-beta regulatory T cell
type: Class
equivalent class: Class
  intersection of: CD8-positive, alpha-beta T cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0050777
subclass of: CD8-positive, alpha-beta T cell
subclass of: regulatory T cell
IAO_0000115: A CD8-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release.
has broad synonym: suppressor T cell
has broad synonym: suppressor T lymphocyte
has broad synonym: suppressor T-cell
has broad synonym: suppressor T-lymphocyte
has exact synonym: CD8+ T(reg)
has exact synonym: CD8+ Treg
has exact synonym: CD8+ regulatory T cell
has exact synonym: CD8-positive T(reg)
has exact synonym: CD8-positive Treg
has exact synonym: CD8-positive, alpha-beta Treg
has exact synonym: CD8-positive, alpha-beta regulatory T lymphocyte
has exact synonym: CD8-positive, alpha-beta regulatory T-cell
has exact synonym: CD8-positive, alpha-beta regulatory T-lymphocyte

CD8-alpha-beta-positive, alpha-beta intraepithelial T cell
type: Class
equivalent class: Class
  intersection of: alpha-beta intraepithelial T cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000025402
subclass of: alpha-beta intraepithelial T cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000025402
IAO_0000115: A alpha-beta intraepithelial T cell found in the columnar epithelium of the gastrointestinal tract. Intraepithelial T cells often have distinct developmental pathways and activation requirements.
has broad synonym: IEL
has broad synonym: intraepithelial lymphocyte
has exact synonym: CD8-positive, alpha-beta intraepithelial T lymphocyte
has exact synonym: CD8-positive, alpha-beta intraepithelial T-cell
has exact synonym: CD8-positive, alpha-beta intraepithelial T-lymphocyte

alpha-beta intraepithelial T cell
type: Class
equivalent class: Class
  intersection of: mature alpha-beta T cell
  intersection of: Restriction
    on property: RO_0001025
    some values from: UBERON_0001277
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002385
subclass of: mature alpha-beta T cell
subclass of: intraepithelial lymphocyte
IAO_0000115: A mature alpha-beta T cell of the columnar epithelium of the gastrointestinal tract. Intraepithelial T cells often have distinct developmental pathways and activation requirements.
has broad synonym: IEL
has broad synonym: intraepithelial lymphocyte
has exact synonym: alpha-beta intraepithelial T lymphocyte
has exact synonym: alpha-beta intraepithelial T-cell
has exact synonym: alpha-beta intraepithelial T-lymphocyte

gamma-delta T cell
type: Class
equivalent class: Class
  intersection of: T cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0042106
subclass of: T cell
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0042106
IAO_0000115: A T cell that expresses a gamma-delta T cell receptor complex.
has exact synonym: gamma-delta T lymphocyte
has exact synonym: gamma-delta T-cell
has exact synonym: gamma-delta T-lymphocyte
has exact synonym: gammadelta T cell
has related synonym: gd T cell

immature gamma-delta T cell
type: Class
equivalent class: Class
  intersection of: gamma-delta T cell
  intersection of: Restriction
    on property: has_not_completed
    some values from: GO_0042492
  intersection of: Restriction
    on property: has_not_completed
    some values from: GO_0045058
subclass of: gamma-delta T cell
subclass of: immature T cell
subclass of: Restriction
  on property: has_not_completed
  some values from: GO_0042492
subclass of: Restriction
  on property: RO_0002202
  some values from: DN3 thymocyte
IAO_0000115: A gamma-delta T cell that has an immature phenotype.
has exact synonym: immature gamma-delta T lymphocyte
has exact synonym: immature gamma-delta T-cell
has exact synonym: immature gamma-delta T-lymphocyte

mature gamma-delta T cell
type: Class
equivalent class: Class
  intersection of: gamma-delta T cell
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0045058
subclass of: gamma-delta T cell
subclass of: mature T cell
subclass of: Restriction
  on property: RO_0002202
  some values from: immature gamma-delta T cell
IAO_0000115: A gamma-delta T cell that has a mature phenotype. These cells can be found in tissues and circulation where they express unique TCR repertoire depending on their location.
has exact synonym: mature gamma-delta T lymphocyte
has exact synonym: mature gamma-delta T-cell
has exact synonym: mature gamma-delta T-lymphocyte

gamma-delta intraepithelial T cell
type: Class
equivalent class: Class
  intersection of: mature gamma-delta T cell
  intersection of: Restriction
    on property: RO_0001025
    some values from: UBERON_0001277
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002385
subclass of: mature gamma-delta T cell
subclass of: intraepithelial lymphocyte
IAO_0000115: A mature gamma-delta T cell that is found in the columnar epithelium of the gastrointestinal tract. These cells participate in mucosal immune responses.
has broad synonym: IEL
has broad synonym: intraepithelial lymphocyte
has exact synonym: gamma-delta intraepithelial T lymphocyte
has exact synonym: gamma-delta intraepithelial T-cell
has exact synonym: gamma-delta intraepithelial T-lymphocyte

CD8-alpha alpha positive, gamma-delta intraepithelial T cell
type: Class
equivalent class: Class
  intersection of: gamma-delta intraepithelial T cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001084
subclass of: gamma-delta intraepithelial T cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001084
IAO_0000115: A gamma-delta intraepithelial T cell that has the phenotype CD8-alpha alpha-positive.
has broad synonym: IEL
has broad synonym: intraepithelial lymphocyte
has exact synonym: CD8-positive, gamma-delta intraepithelial T lymphocyte
has exact synonym: CD8-positive, gamma-delta intraepithelial T-cell
has exact synonym: CD8-positive, gamma-delta intraepithelial T-lymphocyte

CD4-negative CD8-negative gamma-delta intraepithelial T cell
type: Class
equivalent class: Class
  intersection of: gamma-delta intraepithelial T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
subclass of: gamma-delta intraepithelial T cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
IAO_0000115: A gamma-delta intraepithelial T cell that has the phenotype CD4-negative and CD8-negative.
has broad synonym: IEL
has broad synonym: intraepithelial lymphocyte
has exact synonym: CD4-positive, gamma-delta intraepithelial T lymphocyte
has exact synonym: CD4-positive, gamma-delta intraepithelial T-cell
has exact synonym: CD4-positive, gamma-delta intraepithelial T-lymphocyte

immature single positive thymocyte
type: Class
equivalent class: Class
  intersection of: thymocyte
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001307
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001380
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0043384
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000025402
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001932
subclass of: thymocyte
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001307
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001380
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0043384
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000025402
subclass of: Restriction
  on property: RO_0002202
  some values from: DN4 thymocyte
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001932
IAO_0000115: A thymocyte that has the phenotype CD4-negative, CD8-positive, CD44-negative, CD25-negative, and pre-TCR-positive.
has exact synonym: ISP
has exact synonym: T.ISP.th
has exact synonym: immature single positive T cell
has exact synonym: immature single positive T lymphocyte
has exact synonym: immature single positive T-lymphocyte

DN2 thymocyte
type: Class
equivalent class: Class
  intersection of: thymocyte
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000025402
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001307
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001380
subclass of: double negative thymocyte
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001307
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001380
subclass of: Restriction
  on property: RO_0002202
  some values from: DN1 thymic pro-T cell
IAO_0000115: A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-positive.
has exact synonym: DN2 alpha-beta immature T lymphocyte
has exact synonym: DN2 alpha-beta immature T-cell
has exact synonym: DN2 alpha-beta immature T-lymphocyte
has exact synonym: DN2 cell
has exact synonym: DN2 immature T cell
has exact synonym: TN2 cell
has exact synonym: TN2 thymocyte
has exact synonym: double negative 2
has exact synonym: preT.DN2.Th

DN3 thymocyte
type: Class
equivalent class: Class
  intersection of: thymocyte
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001307
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000025402
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0043384
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001380
subclass of: double negative thymocyte
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001307
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0043384
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001380
subclass of: Restriction
  on property: RO_0002202
  some values from: DN2 thymocyte
IAO_0000115: A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, and CD25-positive and expressing the T cell receptor beta-chain in complex with the pre-T cell receptor alpha chain.
has broad synonym: early cortical thymocyte
has exact synonym: DN3 alpha-beta immature T lymphocyte
has exact synonym: DN3 alpha-beta immature T-cell
has exact synonym: DN3 alpha-beta immature T-lymphocyte
has exact synonym: DN3 cell
has exact synonym: DN3 immature T cell
has exact synonym: TN3 cell
has exact synonym: TN3 thymocyte
has exact synonym: double negative 3
has exact synonym: preT.DN3.Th

DN4 thymocyte
type: Class
equivalent class: Class
  intersection of: thymocyte
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001307
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001380
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000025402
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0043384
subclass of: double negative thymocyte
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001307
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001380
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0043384
subclass of: Restriction
  on property: RO_0002202
  some values from: DN3 thymocyte
IAO_0000115: A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, CD25-negative, and pre-TCR-positive.
has broad synonym: early cortical thymocyte
has exact synonym: DN4 alpha-beta immature T lymphocyte
has exact synonym: DN4 alpha-beta immature T-lymphocyte
has exact synonym: DN4 cell
has exact synonym: DN4 immature T cell
has exact synonym: DN4 immature T-cell
has exact synonym: T.DN4.th
has exact synonym: double negative 4

double-positive, alpha-beta thymocyte
type: Class
equivalent class: Class
  intersection of: immature alpha-beta T cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002370
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001004
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000025402
subclass of: immature alpha-beta T cell
subclass of: thymocyte
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001004
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000025402
subclass of: Restriction
  on property: RO_0002202
  some values from: immature single positive thymocyte
IAO_0000115: A thymocyte expressing the alpha-beta T cell receptor complex as well as both the CD4 and CD8 coreceptors.
has broad synonym: late cortical thymocyte
has exact synonym: DP cell
has exact synonym: DP thymocyte
has exact synonym: double-positive, alpha-beta immature T lymphocyte

CD4-positive, alpha-beta thymocyte
type: Class
equivalent class: Class
  intersection of: immature alpha-beta T cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002370
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001004
subclass of: immature alpha-beta T cell
subclass of: thymocyte
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001004
subclass of: Restriction
  on property: RO_0002202
  some values from: double-positive, alpha-beta thymocyte
IAO_0000115: An immature alpha-beta T cell that is located in the thymus and is CD4-positive and CD8-negative.
has exact synonym: CD4-positive, alpha-beta immature T lymphocyte
has exact synonym: CD4-positive, alpha-beta immature T-cell
has exact synonym: CD4-positive, alpha-beta immature T-lymphocyte
has exact synonym: SP CD4 cell

CD8-positive, alpha-beta thymocyte
type: Class
equivalent class: Class
  intersection of: immature alpha-beta T cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002370
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000025402
subclass of: immature alpha-beta T cell
subclass of: thymocyte
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000025402
subclass of: Restriction
  on property: RO_0002202
  some values from: double-positive, alpha-beta thymocyte
IAO_0000115: An immature alpha-beta T cell that is located in the thymus and is CD8-positive and CD4-negative.
has exact synonym: CD8-positive, alpha-beta immature T lymphocyte
has exact synonym: CD8-positive, alpha-beta immature T-cell
has exact synonym: CD8-positive, alpha-beta immature T-lymphocyte
has exact synonym: SP CD8 cell
has related synonym: CD8-positive, alpha-beta immature T cell

memory T cell
type: Class
equivalent class: Class
  intersection of: mature T cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001603
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0002286
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0043379
subclass of: mature T cell
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0001603
subclass of: Restriction
  on property: RO_0002353
  some values from: GO_0043379
disjoint with: naive T cell
IAO_0000115: A long-lived, antigen-experienced T cell that has acquired a memory phenotype including distinct surface markers and the ability to differentiate into an effector T cell upon antigen reexposure.
has exact synonym: memory T lymphocyte
has exact synonym: memory T-cell
has exact synonym: memory T-lymphocyte

mature NK T cell
type: Class
equivalent class: Class
  intersection of: mature alpha-beta T cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001874
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032394
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0045087
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0030217
subclass of: mature alpha-beta T cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001874
subclass of: Restriction
  on property: RO_0002202
  some values from: immature NK T cell stage IV
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032394
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0045087
subclass of: Restriction
  on property: RO_0002353
  some values from: GO_0030217
IAO_0000115: A mature alpha-beta T cell of a distinct lineage that bears natural killer markers and a T cell receptor specific for a limited set of ligands. NK T cells have activation and regulatory roles particularly early in an immune response.
has exact synonym: mature NK T lymphocyte
has exact synonym: mature NK T-cell
has exact synonym: mature NK T-lymphocyte
has exact synonym: mature NKT cell
has exact synonym: mature natural killer T cell
has exact synonym: mature natural killer T lymphocyte
has exact synonym: mature natural killer T-cell
has exact synonym: mature natural killer T-lymphocyte

regulatory T cell
type: Class
equivalent class: Class
  intersection of: mature T cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0050777
subclass of: mature T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0050777
IAO_0000115: A T cell which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release.
has broad synonym: suppressor T cell
has broad synonym: suppressor T lymphocyte
has broad synonym: suppressor T-cell
has broad synonym: suppressor T-lymphocyte
has exact synonym: Treg
has exact synonym: regulatory T lymphocyte
has exact synonym: regulatory T-cell
has exact synonym: regulatory T-lymphocyte

immature B cell
type: Class
equivalent class: Class
  intersection of: B cell, CD19-positive
  intersection of: Restriction
    on property: has_not_completed
    some values from: GO_0045190
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0071738
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071753
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001289
subclass of: B cell, CD19-positive
subclass of: Restriction
  on property: has_not_completed
  some values from: GO_0045190
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0071738
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0071753
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001289
subclass of: Restriction
  on property: RO_0002202
  some values from: small pre-B-II cell
IAO_0000115: An immature B cell is a B cell that has the phenotype surface IgM-positive and surface IgD-negative, and have not undergone class immunoglobulin class switching or peripheral encounter with antigen and activation.
has exact synonym: immature B lymphocyte
has exact synonym: immature B-cell
has exact synonym: immature B-lymphocyte
has exact synonym: newly formed B cell

precursor B cell
type: Class
equivalent class: Class
  intersection of: B cell, CD19-positive
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0071753
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001898
subclass of: B cell, CD19-positive
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0071753
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001898
disjoint with: pro-B cell
IAO_0000115: A precursor B cell is a B cell with the phenotype CD10-positive.
has related synonym: pre-B cell

transitional stage B cell
type: Class
equivalent class: Class
  intersection of: B cell, CD19-positive
  intersection of: Restriction
    on property: has_not_completed
    some values from: GO_0002335
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071753
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001289
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001408
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001932
subclass of: B cell, CD19-positive
subclass of: Restriction
  on property: has_not_completed
  some values from: GO_0002335
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0071753
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001289
subclass of: Restriction
  on property: RO_0002202
  some values from: immature B cell
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001408
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001932
IAO_0000115: An immature B cell of an intermediate stage between the pre-B cell stage and the mature naive stage with the phenotype surface IgM-positive and CD19-positive, and are subject to the process of B cell selection. A transitional B cell migrates from the bone marrow into the peripheral circulation, and then to the spleen.
has exact synonym: transitional B cell
has exact synonym: transitional stage B lymphocyte
has exact synonym: transitional stage B-cell
has exact synonym: transitional stage B-lymphocyte
has narrow synonym: T1 B cell
has narrow synonym: T2 B cell
has narrow synonym: T3 B cell

B-1 B cell
type: Class
equivalent class: Class
  intersection of: mature B cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001014
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001289
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001879
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0045087
  intersection of: Restriction
    on property: RO_0015015
    some values from: GO_0071753
subclass of: mature B cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001014
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001289
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001879
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0045087
subclass of: Restriction
  on property: RO_0015015
  some values from: GO_0071753
IAO_0000115: A B cell of distinct lineage and surface marker expression. B-1 B cells are thought to be the primary source of natural IgM immunoglobulin, that is, IgM produced in large quantities without prior antigenic stimulation and generally reactive against various microorganisms, as well as the source of T-independent IgA immunoglobulin in the mucosal areas. These cells are CD43-positive.
has exact synonym: B-1 B lymphocyte
has exact synonym: B-1 B-cell
has exact synonym: B-1 B-lymphocyte
has exact synonym: B-1 cell
has exact synonym: B1 B cell
has exact synonym: B1 B lymphocyte
has exact synonym: B1 B-cell
has exact synonym: B1 B-lymphocyte
has exact synonym: B1 cell

B-1a B cell
type: Class
equivalent class: Class
  intersection of: B-1 B cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001839
subclass of: B-1 B cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001839
IAO_0000115: A B-1 B cell that has the phenotype CD5-positive.
has exact synonym: B-1a B lymphocyte
has exact synonym: B-1a B-cell
has exact synonym: B-1a B-lymphocyte
has exact synonym: B1a B cell
has exact synonym: B1a B lymphocyte
has exact synonym: B1a B-cell
has exact synonym: B1a B-lymphocyte
has exact synonym: B1a cell
has exact synonym: CD5(+) B1 cell
has exact synonym: CD5+ B1 cell
has exact synonym: CD5-positive B1 cell

B-1b B cell
type: Class
equivalent class: Class
  intersection of: B-1 B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
subclass of: B-1 B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
IAO_0000115: A B-1 B cell that has the phenotype CD5-negative, but having other phenotypic attributes of a B-1 B cell.
has exact synonym: B-1b B lymphocyte
has exact synonym: B-1b B-cell
has exact synonym: B-1b B-lymphocyte
has exact synonym: B1b B cell
has exact synonym: B1b B lymphocyte
has exact synonym: B1b B-cell
has exact synonym: B1b B-lymphocyte
has exact synonym: B1b cell

B-2 B cell
type: Class
equivalent class: Class
  intersection of: mature B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001879
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001289
subclass of: mature B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001879
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001289
IAO_0000115: A conventional B cell subject to antigenic stimulation and dependent on T cell help and with a distinct surface marker expression pattern from B-1 B cells. These cells are CD43-negative.
has exact synonym: B-2 B lymphocyte
has exact synonym: B-2 B-cell
has exact synonym: B-2 B-lymphocyte
has exact synonym: B2 B cell
has exact synonym: B2 B lymphocyte
has exact synonym: B2 B-cell
has exact synonym: B2 B-lymphocyte
has exact synonym: B2 cell
has related synonym: B-0 B cell

immature natural killer cell
type: Class
equivalent class: Class
  intersection of: natural killer cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001501
subclass of: natural killer cell
subclass of: immature innate lymphoid cell
subclass of: Restriction
  on property: RO_0002202
  some values from: pre-natural killer cell
disjoint with: pre-natural killer cell
IAO_0000115: A natural killer cell that is developmentally immature and expresses natural killer cell receptors (NKR).
has exact synonym: immature NK cell
has related synonym: p-NK

pro-NK cell
type: Class
equivalent class: Class
  intersection of: lymphoid lineage restricted progenitor cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001874
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002065
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001003
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001015
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001381
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001898
subclass of: lymphoid lineage restricted progenitor cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001874
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002065
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001003
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001015
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001381
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001898
subclass of: Restriction
  on property: RO_0002202
  some values from: common lymphoid progenitor
IAO_0000115: A lymphoid progenitor cell that is committed to the natural killer cell lineage, expressing CD122 (IL-15) receptor, but lacking many of the phenotypic characteristics of later stages of natural killer cell development such as expression of NK activating and inhibitory molecules. In human this cell has the phenotype CD34-positive, CD45RA-positive, CD10-positive, CD117-negative, and CD161 negative.
has exact synonym: NKP
has exact synonym: natural killer cell progenitor
has exact synonym: pro-natural killer cell
has related synonym: null cell
has related synonym: preNK cell

pro-B cell
type: Class
equivalent class: Class
  intersection of: lymphoid lineage restricted progenitor cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000001903
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000006611
  intersection of: Restriction
    on property: RO_0000056
    some values from: GO_0033152
subclass of: lymphoid lineage restricted progenitor cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000001903
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000006611
subclass of: Restriction
  on property: RO_0000056
  some values from: GO_0033152
subclass of: Restriction
  on property: RO_0002202
  some values from: common lymphoid progenitor
IAO_0000115: A progenitor cell of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but not yet fully committed to the B cell lineage until the expression of PAX5 occurs.
has broad synonym: pre-pro B cell
has exact synonym: pro-B lymphocyte
has exact synonym: pro-B-cell
has exact synonym: pro-B-lymphocyte
has exact synonym: progenitor B cell
has exact synonym: progenitor B lymphocyte
has exact synonym: progenitor B-cell
has exact synonym: progenitor B-lymphocyte
has related synonym: pre-B cell (Philadelphia nomenclature)

pro-T cell
type: Class
equivalent class: Class
  intersection of: lymphoid lineage restricted progenitor cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030217
subclass of: lymphoid lineage restricted progenitor cell
subclass of: Restriction
  on property: RO_0002202
  some values from: common lymphoid progenitor
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030217
IAO_0000115: A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage.
has exact synonym: pro-T lymphocyte
has exact synonym: progenitor T cell
has narrow synonym: DN1 cell
has narrow synonym: DN1 thymocyte
has narrow synonym: TN1 cell

thromboblast
type: Class
equivalent class: Class
  intersection of: myeloid lineage restricted progenitor cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001407
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002574
subclass of: single nucleate cell
subclass of: myeloid cell
subclass of: myeloid lineage restricted progenitor cell
subclass of: Restriction
  on property: RO_0002202
  some values from: megakaryocyte-erythroid progenitor cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002574
IAO_0000115: A progenitor cell of the thrombocyte, a nucleated blood cell involved in coagulation typically seen in birds and other non-mammalian vertebrates.

basophilic myeloblast
type: Class
equivalent class: Class
  intersection of: myeloblast
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030221
subclass of: myeloblast
subclass of: Restriction
  on property: RO_0002202
  some values from: basophil progenitor cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030221
IAO_0000115: A myeloblast committed to the basophil lineage.

basophilic promyelocyte
type: Class
equivalent class: Class
  intersection of: promyelocyte
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030221
subclass of: promyelocyte
subclass of: Restriction
  on property: RO_0002202
  some values from: basophilic myeloblast
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030221
IAO_0000115: A promyelocyte committed to the basophil lineage.

mast cell progenitor
type: Class
equivalent class: Class
  intersection of: myeloid lineage restricted progenitor cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000007857
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000007858
  intersection of: Restriction
    on property: lacks_part
    some values from: PR_000005307
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001963
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002979
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002980
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002981
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000005178
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000016401
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0060374
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000009143
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000002065
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000007431
subclass of: myeloid cell
subclass of: myeloid lineage restricted progenitor cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000007857
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000007858
subclass of: Restriction
  on property: lacks_part
  some values from: PR_000005307
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001963
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002979
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002980
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002981
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000005178
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000016401
subclass of: Restriction
  on property: RO_0002202
  some values from: basophil mast progenitor cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0060374
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000009143
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000002065
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000007431
IAO_0000115: A progenitor cell of the mast cell lineage. Markers for this cell are FceRIa-low, CD117-positive, CD9-positive, T1/ST2-positive, SCA1-negative, and lineage-negative.
has exact synonym: MCP
has related synonym: CFU-MC
has related synonym: CFU-Mast
has related synonym: colony forming unit mast cell

eosinophilic myeloblast
type: Class
equivalent class: Class
  intersection of: myeloblast
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030222
subclass of: myeloblast
subclass of: Restriction
  on property: RO_0002202
  some values from: eosinophil progenitor cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030222
IAO_0000115: A myeloblast committed to the eosinophil lineage.

eosinophilic promyelocyte
type: Class
equivalent class: Class
  intersection of: promyelocyte
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030222
subclass of: promyelocyte
subclass of: Restriction
  on property: RO_0002202
  some values from: eosinophilic myeloblast
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030222
IAO_0000115: A promyelocyte committed to the eosinophil lineage.

neutrophil progenitor cell
type: Class
equivalent class: Class
  intersection of: granulocytopoietic cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030223
subclass of: myeloid cell
subclass of: granulocytopoietic cell
subclass of: Restriction
  on property: RO_0002202
  some values from: granulocyte monocyte progenitor cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030223
IAO_0000115: A progenitor cell of the neutrophil lineage.
has related synonym: neutrophil stem cell

myeloblast
type: Class
equivalent class: Class
  intersection of: granulocytopoietic cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: CL_0017503
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0000791
  intersection of: Restriction
    on property: lacks_part
    some values from: GO_0042582
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0040072
subclass of: myeloid cell
subclass of: granulocytopoietic cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: CL_0017503
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0000791
subclass of: Restriction
  on property: lacks_part
  some values from: GO_0042582
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0040072
subclass of: Restriction
  on property: RO_0002202
  some values from: granulocyte monocyte progenitor cell
IAO_0000115: The most primitive precursor in the granulocytic series, having fine, evenly distributed chromatin, several nucleoli, a high nuclear-to-cytoplasmic ration (5:1-7:1), and a nongranular basophilic cytoplasm. They reside in the bone marrow.

promyelocyte
type: Class
equivalent class: Class
  intersection of: myeloid lineage restricted progenitor cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: CL_0017503
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0005730
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0042582
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001483
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001932
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0040072
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001456
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001892
subclass of: myeloid cell
subclass of: granulocytopoietic cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: CL_0017503
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0005730
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0042582
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001483
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001932
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0040072
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001456
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001892
subclass of: Restriction
  on property: RO_0002202
  some values from: myeloblast
IAO_0000115: A precursor in the granulocytic series, being a cell intermediate in development between a myeloblast and myelocyte, that has distinct nucleoli, a nuclear-to-cytoplasmic ratio of 5:1 to 3:1, and containing a few primary cytoplasmic granules. Markers for this cell are fucosyltransferase FUT4-positive, CD33-positive, integrin alpha-M-negative, low affinity immunoglobulin gamma Fc region receptor III-negative, and CD24-negative.

hematopoietic multipotent progenitor cell
type: Class
equivalent class: Class
  intersection of: hematopoietic cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001869
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002981
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001402
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001003
subclass of: BFO_0000002
subclass of: CL_0008001
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001869
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002981
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0001402
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001003
subclass of: Restriction
  on property: RO_0002202
  some values from: hematopoietic stem cell
disjoint with: hematopoietic oligopotent progenitor cell
IAO_0000115: A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans.
has exact synonym: MPP
has exact synonym: hemopoietic progenitor cell

lymphoid lineage restricted progenitor cell
type: Class
equivalent class: Class
  intersection of: hematopoietic lineage restricted progenitor cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030098
subclass of: hematopoietic lineage restricted progenitor cell
subclass of: CL_0011026
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030098
disjoint with: myeloid lineage restricted progenitor cell
IAO_0000115: A progenitor cell restricted to the lymphoid lineage.
has broad synonym: lymphoid progenitor cell

myeloid lineage restricted progenitor cell
type: Class
equivalent class: Class
  intersection of: hematopoietic lineage restricted progenitor cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030099
subclass of: hematopoietic lineage restricted progenitor cell
subclass of: CL_0011026
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030099
IAO_0000115: A progenitor cell restricted to the myeloid lineage.
has broad synonym: myeloid progenitor cell

immature conventional dendritic cell
type: Class
equivalent class: Class
  intersection of: conventional dendritic cell
  intersection of: Restriction
    on property: RO_0015016
    some values from: GO_0042613
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001412
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001438
subclass of: myeloid leukocyte
subclass of: conventional dendritic cell
subclass of: Restriction
  on property: RO_0002202
  some values from: common dendritic progenitor
subclass of: Restriction
  on property: RO_0015016
  some values from: GO_0042613
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001412
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001438
IAO_0000115: An immature cell of the conventional dendritic cell lineage, characterized by high levels of antigen uptake via endocytosis, macropinocytosis, and phagocytosis, and typically found resident in the tissues. Markers for this cell are CD80-low, CD86-low, and MHC-II-low.
has narrow synonym: immature myeloid dendritic cell

mature conventional dendritic cell
type: Class
equivalent class: Class
  intersection of: conventional dendritic cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001310
  intersection of: Restriction
    on property: RO_0015015
    some values from: GO_0042613
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001412
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001438
subclass of: myeloid leukocyte
subclass of: conventional dendritic cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001310
subclass of: Restriction
  on property: RO_0002202
  some values from: immature conventional dendritic cell
subclass of: Restriction
  on property: RO_0015015
  some values from: GO_0042613
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001412
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001438
IAO_0000115: A mature cell of the conventional dendritic cell lineage, characterized by a high capacity for antigen presentation and typically found in a lymph node.
has broad synonym: mature dendritic cell
has narrow synonym: mature myeloid dendritic cell

mononuclear cell
type: Class
equivalent class: Class
  intersection of: leukocyte
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001407
subclass of: single nucleate cell
subclass of: leukocyte
IAO_0000115: A leukocyte with a single non-segmented nucleus in the mature form.
has exact synonym: mononuclear leukocyte
has narrow synonym: peripheral blood mononuclear cell

follicular B cell
type: Class
equivalent class: Class
  intersection of: mature B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001879
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002037
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071738
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071753
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001014
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001289
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001338
subclass of: B-2 B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002037
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0071738
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0071753
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001014
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001338
IAO_0000115: A resting mature B cell that has the phenotype IgM-positive, IgD-positive, CD23-positive and CD21-positive, and found in the B cell follicles of the white pulp of the spleen or the corticol areas of the peripheral lymph nodes. This cell type is also described as being CD19-positive, B220-positive, AA4-negative, CD43-negative, and CD5-negative.
has exact synonym: Fo B cell
has exact synonym: Fo B-cell
has exact synonym: follicular B lymphocyte
has exact synonym: follicular B-cell
has exact synonym: follicular B-lymphocyte

germinal center B cell
type: Class
equivalent class: Class
  intersection of: mature B cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001745
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001289
subclass of: mature B cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001745
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001289
subclass of: Restriction
  on property: RO_0002202
  some values from: follicular B cell
IAO_0000115: A rapidly cycling mature B cell that has distinct phenotypic characteristics and is involved in T-dependent immune responses and located typically in the germinal centers of lymph nodes. This cell type expresses Ly77 after activation.
has exact synonym: GC B cell
has exact synonym: GC B lymphocyte
has exact synonym: GC B-cell
has exact synonym: GC B-lymphocyte
has exact synonym: germinal center B lymphocyte
has exact synonym: germinal center B-cell
has exact synonym: germinal center B-lymphocyte

marginal zone B cell of spleen
type: Class
equivalent class: Class
  intersection of: mature B cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001251
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001880
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002037
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001289
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001338
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0042742
  intersection of: Restriction
    on property: RO_0015015
    some values from: GO_0071753
subclass of: mature B cell
subclass of: CL_2000074
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001251
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001880
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002037
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001289
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001338
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0042742
subclass of: Restriction
  on property: RO_0015015
  some values from: GO_0071753
IAO_0000115: A mature B cell that is located in the marginal zone of the spleen with the phenotype CD23-negative and CD21-positive and expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL. This cell type is also described as being CD19-positive, B220-positive, IgM-high, AA4-negative, CD35-high.
has broad synonym: MZ B cell
has broad synonym: MZ B lymphocyte
has broad synonym: MZ B-cell
has broad synonym: MZ B-lymphocyte
has broad synonym: marginal zone B cell
has broad synonym: marginal zone B lymphocyte
has broad synonym: marginal zone B-cell
has broad synonym: marginal zone B-lymphocyte
has exact synonym: B cell of marginal zone of spleen
has exact synonym: marginal zone of spleen B cell

ciliated olfactory receptor neuron
type: Class
equivalent class: Class
  intersection of: olfactory receptor cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0005929
subclass of: ciliated cell
subclass of: olfactory receptor cell
IAO_0000115: An olfactory receptor cell in which the apical ending of the dendrite is a pronounced ciliated olfactory knob.
has exact synonym: ciliated olfactory sensory neuron
has exact synonym: ciliated sensory neuron

serotonergic neuron
type: Class
equivalent class: Class
  intersection of: neuron
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0060096
subclass of: serotonin secreting cell
subclass of: neuron
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0060096
IAO_0000115: A neuron that releases serotonin as a neurotransmitter.
has exact synonym: 5-HT neuron
has exact synonym: 5-hydroxytryptamine neuron
has related synonym: serotinergic neuron

neuromast mantle cell
type: Class
subclass of: secretory cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0008904
disjoint with: sensory hair cell
IAO_0000115: Neuromast mantle cell is a non-sensory cell. Neuromast mantle cells surround the neuromast support cells and neuromast hair cells, separating the neuromast from the epidermis, and secrete cupula in which the ciliary bundles of all the hair cells are embedded.

neuromast supporting cell
type: Class
subclass of: supporting cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0008904
disjoint with: sensory hair cell
IAO_0000115: Neuromast support cell is a non-sensory cell of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; neuromast support cells are surrounded by neuromast mantle cells.
has exact synonym: neuromast support cell

sensory hair cell
type: Class
subclass of: mechanoreceptor cell
IAO_0000115: Hair cell is a mechanoreceptor cell that is sensitive to movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system.
has broad synonym: hair cell

neuromast hair cell
type: Class
equivalent class: Class
  intersection of: sensory hair cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0008904
subclass of: BFO_0000002
subclass of: neuronal receptor cell
subclass of: sensory hair cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0008904
IAO_0000115: Neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.

slow muscle myoblast
type: Class
equivalent class: Class
  intersection of: myoblast
  intersection of: Restriction
    on property: RO_0002203
    some values from: slow muscle cell
subclass of: skeletal muscle myoblast
subclass of: Restriction
  on property: RO_0002203
  some values from: slow muscle cell
IAO_0000115: A skeletal muscle myoblast that differentiates into slow muscle fibers.

classical monocyte
type: Class
equivalent class: Class
  intersection of: monocyte
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002548
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0006909
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0006954
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001199
subclass of: monocyte
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002548
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0006954
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001199
IAO_0000115: A monocyte that responds rapidly to microbial stimuli by secreting cytokines and antimicrobial factors and which is characterized by high expression of CCR2 in both rodents and humans, negative for the lineage markers CD3, CD19, and CD20, and of larger size than non-classical monocytes.
has exact synonym: inflammatory monocyte

elicited macrophage
type: Class
equivalent class: Class
  intersection of: macrophage
  intersection of: Restriction
    on property: RO_0000056
    some values from: GO_0006954
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001012
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001813
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002064
subclass of: macrophage
subclass of: Restriction
  on property: RO_0000056
  some values from: GO_0006954
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001012
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001813
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002064
subclass of: Restriction
  on property: RO_0002202
  some values from: classical monocyte
IAO_0000115: A macrophage which develops from an inflammatory monocyte and is recruited into the tissues in response to injury and infection as part of an inflammatory response. Markers include CD11b-positive, CD68-positive, and F4/80-positive.
has exact synonym: free macrophage
has exact synonym: wandering histiocyte

suppressor macrophage
type: Class
equivalent class: Class
  intersection of: elicited macrophage
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0050777
subclass of: elicited macrophage
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0050777
IAO_0000115: A macrophage that suppresses immune responses.

inflammatory macrophage
type: Class
equivalent class: Class
  intersection of: elicited macrophage
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032611
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032635
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032640
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0042554
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0042742
subclass of: elicited macrophage
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032611
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032635
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032640
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0042554
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0042742
IAO_0000115: An elicited macrophage that is recruited into the tissues in response to injury and infection as part of an inflammatory response, expresses high levels of pro-inflammatory cytokines, ROS and NO, and shows potent microbicidal activity.
has exact synonym: classically activated macrophage
has related synonym: M1 macrophage

tissue-resident macrophage
type: Class
equivalent class: Class
  intersection of: macrophage
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000479
subclass of: macrophage
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000479
IAO_0000115: A macrophage constitutively resident in a particular tissue under non-inflammatory conditions, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells.
has exact synonym: fixed macrophage
has exact synonym: resting histiocyte

thymic macrophage
type: Class
equivalent class: Class
  intersection of: tissue-resident macrophage
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002370
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0043277
subclass of: tissue-resident macrophage
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002370
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0043277
IAO_0000115: A tissue-resident macrophage resident found in the thymus, involved in the clearance of apoptotic thymocytes.

non-classical monocyte
type: Class
equivalent class: Class
  intersection of: monocyte
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0000587
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0031294
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0030224
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001206
subclass of: monocyte
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0000587
subclass of: Restriction
  on property: RO_0002202
  some values from: intermediate monocyte
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0031294
subclass of: Restriction
  on property: RO_0002353
  some values from: GO_0030224
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001206
IAO_0000115: A type of monocyte characterized by low expression of CCR2, low responsiveness to monocyte chemoattractant CCL2/MCP1, low phagocytic activity, and decrease size relative to classical monocytes, but increased co-stimulatory activity. May also play a role in tissue repair.
has exact synonym: patrolling monocyte
has exact synonym: resident monocyte

central nervous system macrophage
type: Class
equivalent class: Class
  intersection of: tissue-resident macrophage
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001017
subclass of: tissue-resident macrophage
subclass of: neural cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001017
IAO_0000115: A tissue-resident macrophage found in the central nervous system.
has exact synonym: CNS macrophage

myeloid suppressor cell
type: Class
equivalent class: Class
  intersection of: myeloid leukocyte
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001501
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001006
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001012
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0050777
subclass of: myeloid leukocyte
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0001501
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001006
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001012
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0050777
IAO_0000115: An immature myeloid leukocyte of heterogeneous phenotype found particularly in cancer and sepsis patients that is capable of suppressing activity of T cells in ex vivo assays. This cell type is CD45-positive, CD11b-positive.

foam cell
type: Class
subclass of: cell
IAO_0000115: A type of cell containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions.

smooth muscle cell derived foam cell
type: Class
subclass of: BFO_0000002
subclass of: foam cell
subclass of: Restriction
  on property: RO_0002202
  some values from: smooth muscle cell
IAO_0000115: A type of foam cell derived from a smooth muscle cell containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions.

thymocyte
type: Class
equivalent class: Class
  intersection of: T cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002370
  intersection of: Restriction
    on property: has_not_completed
    some values from: GO_0045058
subclass of: immature T cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002370
IAO_0000115: An immature T cell located in the thymus.
has broad synonym: immature T cell
has broad synonym: immature T lymphocyte
has broad synonym: immature T-cell
has broad synonym: immature T-lymphocyte
has exact synonym: thymic lymphocyte

DN1 thymic pro-T cell
type: Class
equivalent class: Class
  intersection of: pro-T cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002370
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001380
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001307
subclass of: pro-T cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002370
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001380
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001307
subclass of: Restriction
  on property: RO_0002202
  some values from: early T lineage precursor
IAO_0000115: A pro-T cell that has the phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-negative.
has exact synonym: DN1 thymic pro-T lymphocyte
has exact synonym: DN1 thymic pro-T-cell
has exact synonym: DN1 thymic pro-T-lymphocyte
has exact synonym: DN1 thymic progenitor T cell
has exact synonym: DN1 thymocyte
has exact synonym: double negative 1
has exact synonym: preT.DN1.Th

naive thymus-derived CD4-positive, alpha-beta T cell
type: Class
equivalent class: Class
  intersection of: CD4-positive, alpha-beta T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001380
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001015
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001203
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001869
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001318
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001307
subclass of: CD4-positive, alpha-beta T cell
subclass of: naive T cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001380
subclass of: Restriction
  on property: RO_0002202
  some values from: mature CD4 single-positive thymocyte
IAO_0000115: An antigen inexperienced CD4-positive, alpha-beta T cell with the phenotype CCR7-positive, CD127-positive and CD62L-positive. This cell type develops in the thymus. This cell type is also described as being CD25-negative, CD62L-high, and CD44-low.
has broad synonym: naive CD4+ T cell
has exact synonym: T.4Nve.Sp
has exact synonym: Th0
has exact synonym: naive thymus-derived CD4-positive, alpha-beta T lymphocyte
has exact synonym: naive thymus-derived CD4-positive, alpha-beta T-cell
has exact synonym: naive thymus-derived CD4-positive, alpha-beta T-lymphocyte

activated CD4-positive, alpha-beta T cell
type: Class
equivalent class: Class
  intersection of: CD4-positive, alpha-beta T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001318
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001869
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001343
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001380
subclass of: CD4-positive, alpha-beta T cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001318
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001869
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001343
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001380
subclass of: Restriction
  on property: RO_0002202
  some values from: naive thymus-derived CD4-positive, alpha-beta T cell
IAO_0000115: A recently activated CD4-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive.
has exact synonym: activated CD4-positive, alpha-beta T lymphocyte
has exact synonym: activated CD4-positive, alpha-beta T-cell
has exact synonym: activated CD4-positive, alpha-beta T-lymphocyte

CD4-positive, alpha-beta memory T cell
type: Class
equivalent class: Class
  intersection of: CD4-positive, alpha-beta T cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001603
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0002286
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0043379
subclass of: CD4-positive, alpha-beta T cell
subclass of: memory T cell
IAO_0000115: A CD4-positive, alpha-beta T cell that has differentiated into a memory T cell.
has exact synonym: CD4-positive, alpha-beta memory T lymphocyte
has exact synonym: CD4-positive, alpha-beta memory T-cell
has exact synonym: CD4-positive, alpha-beta memory T-lymphocyte
has related synonym: T4.Mem.Sp

naive T cell
type: Class
equivalent class: Class
  intersection of: mature T cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001015
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001203
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001869
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0045058
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001318
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001307
subclass of: mature T cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001015
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001203
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001869
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001318
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001307
IAO_0000115: Mature T cell not yet exposed to antigen with the phenotype CCR7-positive, CD45RA-positive, and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low.
has exact synonym: naive T lymphocyte
has exact synonym: naive T-cell
has exact synonym: naive T-lymphocyte

T-helper 17 cell
type: Class
equivalent class: Class
  intersection of: CD4-positive helper T cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000003455
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001207
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001202
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032620
subclass of: CD4-positive helper T cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000003455
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001207
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001202
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032620
IAO_0000115: CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive, CXCR3-negative, CCR6-positive, and capable of producing IL-17.
has exact synonym: IL-17-producing CD4+ T helper
has exact synonym: T helper cells type 17
has exact synonym: T(H)-17 cell
has exact synonym: Th17 CD4+ T cell
has exact synonym: Th17 T cell
has exact synonym: Th17 T lymphocyte
has exact synonym: Th17 T-cell
has exact synonym: Th17 T-lymphocyte
has exact synonym: Th17 cell
has exact synonym: helper T cell type 17

naive thymus-derived CD8-positive, alpha-beta T cell
type: Class
equivalent class: Class
  intersection of: CD8-positive, alpha-beta T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001380
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001015
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001203
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001869
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001318
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001307
subclass of: CD8-positive, alpha-beta T cell
subclass of: naive T cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001380
subclass of: Restriction
  on property: RO_0002202
  some values from: mature CD8 single-positive thymocyte
IAO_0000115: A CD8-positive, alpha-beta T cell that has not experienced activation via antigen contact and has the phenotype CD45RA-positive, CCR7-positive and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low.
has broad synonym: naive CD8+ T cell
has exact synonym: naive thymus-dervied CD8-positive, alpha-beta T lymphocyte
has exact synonym: naive thymus-dervied CD8-positive, alpha-beta T-cell
has exact synonym: naive thymus-dervied CD8-positive, alpha-beta T-lymphocyte
has narrow synonym: T.8Nve.Sp

Tr1 cell
type: Class
equivalent class: Class
  intersection of: CD4-positive, alpha-beta T cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032613
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0050777
subclass of: CD4-positive helper T cell
subclass of: regulatory T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032613
IAO_0000115: CD4-positive alpha-beta T cell with regulatory function that produces IL-10.
has exact synonym: T-regulatory T cell type 1
has exact synonym: Tr1 T cell
has exact synonym: Tr1 T lymphocyte
has exact synonym: Tr1 T-cell
has exact synonym: Tr1 T-lymphocyte

activated CD8-positive, alpha-beta T cell
type: Class
equivalent class: Class
  intersection of: CD8-positive, alpha-beta T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001203
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001318
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001869
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001343
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001380
subclass of: CD8-positive, alpha-beta T cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001203
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001318
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001869
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001343
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001380
subclass of: Restriction
  on property: RO_0002202
  some values from: naive thymus-derived CD8-positive, alpha-beta T cell
IAO_0000115: A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, CD25-positive, and CCR7-negative.
has exact synonym: activated CD8-positive, alpha-beta T lymphocyte
has exact synonym: activated CD8-positive, alpha-beta T-cell
has exact synonym: activated CD8-positive, alpha-beta T-lymphocyte

CD8-positive, alpha-beta cytokine secreting effector T cell
type: Class
equivalent class: Class
  intersection of: CD8-positive, alpha-beta T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001318
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001869
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001343
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001380
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0001816
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0030217
subclass of: CD8-positive, alpha-beta T cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001318
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001869
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001343
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001380
subclass of: Restriction
  on property: RO_0002202
  some values from: activated CD8-positive, alpha-beta T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0001816
subclass of: Restriction
  on property: RO_0002353
  some values from: GO_0030217
IAO_0000115: A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive, that secretes cytokines.
has exact synonym: CD8-positive, alpha-beta cytokine secreting effector T lymphocyte
has exact synonym: CD8-positive, alpha-beta cytokine secreting effector T-cell
has exact synonym: CD8-positive, alpha-beta cytokine secreting effector T-lymphocyte

CD8-positive, alpha-beta memory T cell
type: Class
equivalent class: Class
  intersection of: CD8-positive, alpha-beta T cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001603
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0002286
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0043379
subclass of: CD8-positive, alpha-beta T cell
subclass of: memory T cell
IAO_0000115: A CD8-positive, alpha-beta T cell that has differentiated into a memory T cell.
has exact synonym: CD8-positive, alpha-beta memory T lymphocyte
has exact synonym: CD8-positive, alpha-beta memory T-cell
has exact synonym: CD8-positive, alpha-beta memory T-lymphocyte
has related synonym: T.8Mem.Sp

cytotoxic T cell
type: Class
equivalent class: Class
  intersection of: effector T cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0001913
subclass of: effector T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0001913
IAO_0000115: A mature T cell that differentiated and acquired cytotoxic function with the phenotype perforin-positive and granzyme-B positive.
has exact synonym: cytotoxic T lymphocyte
has exact synonym: cytotoxic T-cell
has exact synonym: cytotoxic T-lymphocyte

effector T cell
type: Class
equivalent class: Class
  intersection of: mature T cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0045026
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0030217
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0045058
subclass of: mature T cell
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0045026
subclass of: Restriction
  on property: RO_0002353
  some values from: GO_0030217
IAO_0000115: A differentiated T cell with ability to traffic to peripheral tissues and is capable of mounting a specific immune response.
has exact synonym: effector T lymphocyte
has exact synonym: effector T-cell
has exact synonym: effector T-lymphocyte

helper T cell
type: Class
equivalent class: Class
  intersection of: effector T cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0001816
subclass of: effector T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0001816
IAO_0000115: A effector T cell that provides help in the form of secreted cytokines to other immune cells.
has exact synonym: T-helper cell
has exact synonym: helper T lymphocyte
has exact synonym: helper T-cell
has exact synonym: helper T-lymphocyte

immature NK T cell
type: Class
equivalent class: Class
  intersection of: immature alpha-beta T cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000003469
subclass of: immature alpha-beta T cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000003469
subclass of: Restriction
  on property: RO_0002202
  some values from: double-positive, alpha-beta thymocyte
IAO_0000115: An immature alpha-beta T-cell that express Egr2. These cells give rise to T cells expressing NK markers.
has exact synonym: immature NK T lymphocyte
has exact synonym: immature NK T-cell
has exact synonym: immature NK T-lymphocyte
has exact synonym: immature NKT cell

CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell
type: Class
equivalent class: Class
  intersection of: alpha-beta intraepithelial T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001084
subclass of: alpha-beta intraepithelial T cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001084
subclass of: Restriction
  on property: RO_0002202
  some values from: CD8-positive, alpha-beta thymocyte
IAO_0000115: An alpha-beta intraepithelial T cell with the phenotype CD8-alpha-alpha-positive located in the columnar epithelium of the gastrointestinal tract. These cells have a memory phenotype of CD2-negative and CD5-negative.
has exact synonym: CD8-alpha-alpha-positive, alpha-beta intraepithelial T lymphocyte
has exact synonym: CD8-alpha-alpha-positive, alpha-beta intraepithelial T-cell
has exact synonym: CD8-alpha-alpha-positive, alpha-beta intraepithelial T-lymphocyte

dendritic epidermal T cell
type: Class
equivalent class: Class
  intersection of: mature gamma-delta T cell
  intersection of: Restriction
    on property: RO_0001025
    some values from: UBERON_0001003
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0060054
subclass of: mature gamma-delta T cell
subclass of: Restriction
  on property: RO_0001025
  some values from: UBERON_0001003
subclass of: Restriction
  on property: RO_0002202
  some values from: mature dendritic epithelial T cell precursor
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0060054
IAO_0000115: A mature gamma-delta T cell located in the epidermis that regulates wound healing.
has exact synonym: DETC
has exact synonym: dendritic epidermal T lymphocyte
has exact synonym: dendritic epidermal T-cell
has exact synonym: dendritic epidermal T-lymphocyte

Tc2 cell
type: Class
equivalent class: Class
  intersection of: CD8-positive, alpha-beta cytokine secreting effector T cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000001941
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001202
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001207
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032633
subclass of: CD8-positive, alpha-beta cytokine secreting effector T cell
subclass of: CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000001941
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032633
IAO_0000115: A CD8-positive, alpha-beta positive T cell expressing GATA-3 and secreting IL-4.
has exact synonym: CD8-positive Th2 cell
has exact synonym: T-cytotoxic T cell type 2
has exact synonym: Tc2 T cell
has exact synonym: Tc2 T lymphocyte
has exact synonym: Tc2 T-cell
has exact synonym: Tc2 T-lymphocyte
has exact synonym: Th2 CD8-positive T cell
has exact synonym: Th2 non-TFH CD8-positive T cell

type I NK T cell
type: Class
equivalent class: Class
  intersection of: mature NK T cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0043208
subclass of: mature NK T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0043208
IAO_0000115: An alpha-beta T cell expressing NK cell markers that is CD1d restricted and expresses specific V-alpha chains. NK T cells of this type recognize the glycolipid alpha-galactosylceramide in the context of CD1d.
has exact synonym: classical NK T cell
has exact synonym: type I NK T lymphocyte
has exact synonym: type I NK T-cell
has exact synonym: type I NK T-lymphocyte
has exact synonym: type I NKT cell
has related synonym: invariant NK T cell

type II NK T cell
type: Class
equivalent class: Class
  intersection of: mature NK T cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002288
subclass of: mature NK T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002288
IAO_0000115: An alpha-beta T cell expressing NK call markers that is CD1d restricted and expresses a diverse TCR repertoire. Type II NKT cells do not become activated by alpha-galactosylceramide when presented by CD1d.
has exact synonym: type II NK T lymphocyte
has exact synonym: type II NK T-cell
has exact synonym: type II NK T-lymphocyte
has exact synonym: type II NKT cell

CD4-positive type I NK T cell
type: Class
equivalent class: Class
  intersection of: type I NK T cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001004
subclass of: type I NK T cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001004
IAO_0000115: A type I NK T cell that has the phenotype CD4-positive.
has exact synonym: CD4-positive type I NK T lymphocyte
has exact synonym: CD4-positive type I NK T-cell
has exact synonym: CD4-positive type I NK T-lymphocyte
has exact synonym: CD4-positive type I NKT cell
has narrow synonym: NKT.4+.SP

CD4-negative, CD8-negative type I NK T cell
type: Class
equivalent class: Class
  intersection of: type I NK T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
subclass of: type I NK T cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
IAO_0000115: A type I NK T cell that has the phenotype CD4-negative and CD8-negative.
has exact synonym: CD4-negative, CD8-negative type I NK T lymphocyte
has exact synonym: CD4-negative, CD8-negative type I NK T-cell
has exact synonym: CD4-negative, CD8-negative type I NK T-lymphocyte
has exact synonym: CD4-negative, CD8-negative type I NKT cell
has narrow synonym: NKT.4-.Sp

activated CD4-positive type I NK T cell
type: Class
equivalent class: Class
  intersection of: type I NK T cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001004
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001343
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032609
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032633
subclass of: CD4-positive type I NK T cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001343
subclass of: Restriction
  on property: RO_0002202
  some values from: CD4-positive type I NK T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032609
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032633
IAO_0000115: A type I NK T cell that has been recently activated, secretes interferon-gamma and IL-4, and has the phenotype CD4-positive, CD69-positive, and downregulated NK markers.
has exact synonym: activated CD4-positive type I NK T lymphocyte
has exact synonym: activated CD4-positive type I NK T-cell
has exact synonym: activated CD4-positive type I NK T-lymphocyte
has exact synonym: activated CD4-positive type I NKT cell

CD4-positive type I NK T cell secreting interferon-gamma
type: Class
equivalent class: Class
  intersection of: type I NK T cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001004
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002827
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032609
subclass of: CD4-positive type I NK T cell
subclass of: Restriction
  on property: RO_0002202
  some values from: activated CD4-positive type I NK T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002827
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032609
IAO_0000115: A mature NK T cell that secretes interferon-gamma and enhances type 1 immune responses.
has exact synonym: CD4-positive type I NK T cell secreting IFN-gamma
has exact synonym: CD4-positive type I NK T lymphocyte secreting interferon-gamma
has exact synonym: CD4-positive type I NK T-cell secreting interferon-gamma
has exact synonym: CD4-positive type I NK T-lymphocyte secreting interferon-gamma
has exact synonym: CD4-positive type I NKT cell secreting interferon-gamma

CD4-positive type I NK T cell secreting interleukin-4
type: Class
equivalent class: Class
  intersection of: type I NK T cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001004
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002830
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032616
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032633
subclass of: CD4-positive type I NK T cell
subclass of: Restriction
  on property: RO_0002202
  some values from: activated CD4-positive type I NK T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002830
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032616
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032633
IAO_0000115: A mature NK T cell that predominantly secretes type 2 cytokines such as interleukin-4 and interleukin-13 and enhances type 2 immune responses.
has exact synonym: CD4-positive type I NK T cell secreting IL-4
has exact synonym: CD4-positive type I NK T lymphocyte secreting interleukin-4
has exact synonym: CD4-positive type I NK T-cell secreting interleukin-4
has exact synonym: CD4-positive type I NK T-lymphocyte secreting interleukin-4
has exact synonym: CD4-positive type I NKT cell secreting interleukin-4

activated CD4-negative, CD8-negative type I NK T cell
type: Class
equivalent class: Class
  intersection of: type I NK T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001343
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002369
subclass of: CD4-negative, CD8-negative type I NK T cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001343
subclass of: Restriction
  on property: RO_0002202
  some values from: CD4-negative, CD8-negative type I NK T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002369
IAO_0000115: A type I NK T cell that has been recently activated, secretes interferon-gamma and interleukin-4, and has phenotype CD4-negative, CD8-negative, CD69-positive, and downregulated NK markers.
has exact synonym: activated CD4-negative, CD8-negative type I NK T lymphocyte
has exact synonym: activated CD4-negative, CD8-negative type I NK T-cell
has exact synonym: activated CD4-negative, CD8-negative type I NK T-lymphocyte
has exact synonym: activated CD4-negative, CD8-negative type I NKT cell

CD4-negative, CD8-negative type I NK T cell secreting interferon-gamma
type: Class
equivalent class: Class
  intersection of: type I NK T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002827
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032609
subclass of: CD4-negative, CD8-negative type I NK T cell
subclass of: Restriction
  on property: RO_0002202
  some values from: activated CD4-negative, CD8-negative type I NK T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002827
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032609
IAO_0000115: A mature NK T cell that secretes interferon-gamma and enhances Th1 immune responses.
has exact synonym: CD4-negative, CD8-negative type I NK T cell secreting IFN-gamma
has exact synonym: CD4-negative, CD8-negative type I NK T lymphocyte secreting interferon-gamma
has exact synonym: CD4-negative, CD8-negative type I NK T-cell secreting interferon-gamma
has exact synonym: CD4-negative, CD8-negative type I NK T-lymphocyte secreting interferon-gamma
has exact synonym: CD4-negative, CD8-negative type I NKT cell secreting interferon-gamma

CD4-negative, CD8-negative type I NK T cell secreting interleukin-4
type: Class
equivalent class: Class
  intersection of: type I NK T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002830
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032633
subclass of: CD4-negative, CD8-negative type I NK T cell
subclass of: Restriction
  on property: RO_0002202
  some values from: activated CD4-negative, CD8-negative type I NK T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002830
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032633
IAO_0000115: A mature NK T cell that secretes interleukin-4 and enhances Th2 immune responses.
has exact synonym: CD4-negative, CD8-negative type I NK T cell secreting IL-4
has exact synonym: CD4-negative, CD8-negative type I NK T lymphocyte secreting interleukin-4
has exact synonym: CD4-negative, CD8-negative type I NK T-cell secreting interleukin-4
has exact synonym: CD4-negative, CD8-negative type I NK T-lymphocyte secreting interleukin-4
has exact synonym: CD4-negative, CD8-negative type I NKT cell secreting interleukin-4

activated type II NK T cell
type: Class
equivalent class: Class
  intersection of: type II NK T cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001343
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002369
subclass of: type II NK T cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001343
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002369
IAO_0000115: A type II NK T cell that has been recently activated, secretes interferon-gamma and interleukin-4, and has the phenotype CD69-positive and downregulated NK markers.
has exact synonym: activated type II NK T lymphocyte
has exact synonym: activated type II NK T-cell
has exact synonym: activated type II NK T-lymphocyte
has exact synonym: activated type II NKT cell

type II NK T cell secreting interferon-gamma
type: Class
equivalent class: Class
  intersection of: type II NK T cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001343
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032609
subclass of: type II NK T cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001343
subclass of: Restriction
  on property: RO_0002202
  some values from: activated type II NK T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032609
IAO_0000115: A type II NK T cell that has been recently activated, secretes interferon-gamma, and has the phenotype CD69-positive and downregulated NK markers.
has exact synonym: type II NK T cell secreting IFN-gamma
has exact synonym: type II NK T lymphocyte secreting interferon-gamma
has exact synonym: type II NK T-cell secreting interferon-gamma
has exact synonym: type II NK T-lymphocyte secreting interferon-gamma
has exact synonym: type II NKT cell secreting interferon-gamma

type II NK T cell secreting interleukin-4
type: Class
equivalent class: Class
  intersection of: type II NK T cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001343
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032633
subclass of: type II NK T cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001343
subclass of: Restriction
  on property: RO_0002202
  some values from: activated type II NK T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032633
IAO_0000115: A type II NK T cell that has been recently activated, secretes interleukin-4, and has the phenotype CD69-positive and downregulated NK markers.
has exact synonym: type II NK T cell secreting IL-4
has exact synonym: type II NK T lymphocyte secreting interleukin-4
has exact synonym: type II NK T-cell secreting interleukin-4
has exact synonym: type II NK T-lymphocyte secreting interleukin-4
has exact synonym: type II NKT cell secreting interleukin-4

CD4-positive, alpha-beta cytotoxic T cell
type: Class
equivalent class: Class
  intersection of: CD4-positive, alpha-beta T cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0001913
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0030217
subclass of: CD4-positive, alpha-beta T cell
subclass of: Restriction
  on property: RO_0002202
  some values from: activated CD4-positive, alpha-beta T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0001913
subclass of: Restriction
  on property: RO_0002353
  some values from: GO_0030217
IAO_0000115: A CD4-positive, alpha-beta T cell that has cytotoxic function.
has exact synonym: CD4-positive, alpha-beta cytotoxic T lymphocyte
has exact synonym: CD4-positive, alpha-beta cytotoxic T-cell
has exact synonym: CD4-positive, alpha-beta cytotoxic T-lymphocyte

early lymphoid progenitor
type: Class
equivalent class: Class
  intersection of: hematopoietic multipotent progenitor cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001460
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002001
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002065
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002979
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030098
subclass of: hematopoietic multipotent progenitor cell
subclass of: CL_0011026
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001460
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002001
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002065
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002979
subclass of: Restriction
  on property: RO_0002202
  some values from: Slamf1-negative multipotent progenitor cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030098
IAO_0000115: A lymphoid progenitor cell that is found in bone marrow, gives rise to B cells, T cells, natural killer cells and dendritic cells, and has the phenotype Lin-negative, Kit-positive, Sca-1-positive, FLT3-positive, CD34-positive, CD150 negative, and GlyA-negative.
has exact synonym: lymphoid-primed multipotent progenitor
has related synonym: ELP
has related synonym: GMLP
has related synonym: LMPP

pre-natural killer cell
type: Class
equivalent class: Class
  intersection of: natural killer cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001003
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001381
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002065
subclass of: natural killer cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001003
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001381
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002065
IAO_0000115: Cell committed to natural killer cell lineage that has the phenotype CD122-positive, CD34-positive, and CD117-positive. This cell type lacks expression of natural killer receptor proteins.
has exact synonym: pre-NK cell

mucosal invariant T cell
type: Class
equivalent class: Class
  intersection of: mature alpha-beta T cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002227
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032394
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0030217
subclass of: mature alpha-beta T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002227
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032394
subclass of: Restriction
  on property: RO_0002353
  some values from: GO_0030217
IAO_0000115: An alpha-beta T cell that is found in the lamina propria of mucosal tissues and is restricted by the MR-1 molecule.
has exact synonym: mucosal invariant T lymphocyte
has exact synonym: mucosal invariant T-cell
has exact synonym: mucosal invariant T-lymphocyte

thymic conventional dendritic cell
type: Class
equivalent class: Class
  intersection of: conventional dendritic cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002370
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001015
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001013
subclass of: conventional dendritic cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002370
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001015
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001013
subclass of: Restriction
  on property: RO_0002202
  some values from: DN1 thymic pro-T cell
IAO_0000115: A dendritic cell arising in thymus that has the phenotype CD11c-positive, CD11b-negative, and CD45RA-negative.

thymic plasmacytoid dendritic cell
type: Class
equivalent class: Class
  intersection of: plasmacytoid dendritic cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001015
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001865
subclass of: plasmacytoid dendritic cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001015
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001865
subclass of: Restriction
  on property: RO_0002202
  some values from: DN1 thymic pro-T cell
IAO_0000115: A plasmacytoid dendritic cell developing in the thymus with phenotype CD11c-negative or low, CD45RA-positive, CD11b-negative, and CD123-positive.

Be1 Cell
type: Class
equivalent class: Class
  intersection of: Be cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032609
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032623
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032640
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0045627
subclass of: Be cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032609
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032623
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032640
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0045627
IAO_0000115: A Be cell that facilitates development of T-helper 1 (Th1) phenotype in CD4-positive T cells, and secretes high levels of interleukin-2, tumor necrosis factor-alpha and interferon-gamma.
has exact synonym: B effector 1 cell
has related synonym: B effector cell type 1

Be2 cell
type: Class
equivalent class: Class
  intersection of: Be cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032613
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032623
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032633
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032635
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0045630
subclass of: Be cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032613
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032623
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032633
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032635
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0045630
IAO_0000115: A Be cell that facilitates development of T-helper 2 (Th2) phenotype T cells, and secretes high levels of interleukin-2, interleukin-10, interleukin-4, and interleukin-6.
has exact synonym: B effector 2 cell
has related synonym: B effector cell type 2

lymphocyte of B lineage
type: Class
subclass of: lymphocyte
subclass of: Restriction
  on property: RO_0002202
  some values from: pro-B cell
IAO_0000115: A lymphocyte of B lineage with the commitment to express an immunoglobulin complex.

antibody secreting cell
type: Class
equivalent class: Class
  intersection of: lymphocyte of B lineage
  intersection of: Restriction
    on property: RO_0003000
    some values from: GO_0042571
subclass of: lymphocyte of B lineage
subclass of: Restriction
  on property: RO_0003000
  some values from: GO_0042571
IAO_0000115: A lymphocyte of B lineage that is devoted to secreting large amounts of immunoglobulin.

IgE plasma cell
type: Class
equivalent class: Class
  intersection of: long lived plasma cell
  intersection of: Restriction
    on property: RO_0003000
    some values from: GO_0071743
subclass of: long lived plasma cell
subclass of: Restriction
  on property: RO_0003000
  some values from: GO_0071743
IAO_0000115: A long lived plasma cell that secretes IgE.

IgE memory B cell
type: Class
equivalent class: Class
  intersection of: class switched memory B cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071742
subclass of: class switched memory B cell
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0071742
IAO_0000115: A class switched memory B cell that expresses IgE on the cell surface.
has exact synonym: IgE memory B lymphocyte
has exact synonym: IgE memory B-cell
has exact synonym: IgE memory B-lymphocyte
has exact synonym: memory IgE B cell
has exact synonym: memory IgE B lymphocyte
has exact synonym: memory IgE B-cell
has exact synonym: memory IgE B-lymphocyte

IgD plasmablast
type: Class
equivalent class: Class
  intersection of: plasmablast
  intersection of: Restriction
    on property: RO_0003000
    some values from: GO_0071739
subclass of: plasmablast
subclass of: Restriction
  on property: RO_0003000
  some values from: GO_0071739
IAO_0000115: A plasmablast that secretes IgD, and which occur in a small proportion of B cells in the adult.

IgE plasmablast
type: Class
equivalent class: Class
  intersection of: plasmablast
  intersection of: Restriction
    on property: RO_0003000
    some values from: GO_0071743
subclass of: plasmablast
subclass of: Restriction
  on property: RO_0003000
  some values from: GO_0071743
IAO_0000115: A plasmablast that secretes IgE.

IgE short lived plasma cell
type: Class
equivalent class: Class
  intersection of: short lived plasma cell
  intersection of: Restriction
    on property: RO_0003000
    some values from: GO_0071743
subclass of: short lived plasma cell
subclass of: Restriction
  on property: RO_0003000
  some values from: GO_0071743
IAO_0000115: A short lived plasma cell that secretes IgE.

preBCR-positive large pre-B-II cell
type: Class
equivalent class: Class
  intersection of: large pre-B-II cell
  intersection of: Restriction
    on property: has_not_completed
    some values from: GO_0071708
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0035369
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001858
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001859
subclass of: large pre-B-II cell
subclass of: Restriction
  on property: has_not_completed
  some values from: GO_0071708
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0035369
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001858
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001859
IAO_0000115: An preBRC-positive large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-positive, composed of surrogate light chain protein (SL), which is composed of VpreB , Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu) on the cell surface.

preBCR-negative large pre-B-II cell
type: Class
equivalent class: Class
  intersection of: large pre-B-II cell
  intersection of: Restriction
    on property: has_not_completed
    some values from: GO_0071708
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0035369
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001858
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001859
subclass of: large pre-B-II cell
subclass of: Restriction
  on property: has_not_completed
  some values from: GO_0071708
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0035369
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001858
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001859
IAO_0000115: A pre-BCR-negative large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-negative, composed of surrogate light chain protein (SL), which is composed of VpreB and Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu), on the cell surface, and lack a DNA rearrangement of immunoglobulin light chain genes.

small pre-B-II cell
type: Class
equivalent class: Class
  intersection of: pre-B-II cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000003457
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000003460
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0019815
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0035369
  intersection of: Restriction
    on property: RO_0000056
    some values from: GO_0071708
subclass of: pre-B-II cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000003457
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000003460
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0019815
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0035369
subclass of: Restriction
  on property: RO_0000056
  some values from: GO_0071708
IAO_0000115: A small pre-B-II cell is a pre-B-II cell that is Rag1-positive, Rag2-positive, pre-BCR-negative, and BCR-negative, is not proliferating, and carries a DNA rearrangement of one or more immunoglobulin light chain genes.
has exact synonym: small pre-BII cell

pre-B-II cell
type: Class
equivalent class: Class
  intersection of: precursor B cell
  intersection of: Restriction
    on property: lacks_part
    some values from: PR_000006611
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001003
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0071707
subclass of: precursor B cell
subclass of: Restriction
  on property: lacks_part
  some values from: PR_000006611
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001003
subclass of: Restriction
  on property: RO_0002353
  some values from: GO_0071707
disjoint with: pre-B-I cell
IAO_0000115: A pre-B-II cell is a precursor B cell that expresses immunoglobulin mu heavy chain (IgHmu+), and lack expression of CD34, TdT, immunoglobulin kappa light chain and immunoglobulin lambda light chain.
has exact synonym: pre-B-lymphocyte
has exact synonym: pre-BII cell

pre-B-I cell
type: Class
equivalent class: Class
  intersection of: precursor B cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000003457
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000003460
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000006611
  intersection of: Restriction
    on property: RO_0000056
    some values from: GO_0071707
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001003
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001858
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001859
subclass of: precursor B cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000003457
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000003460
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000006611
subclass of: Restriction
  on property: RO_0000056
  some values from: GO_0071707
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001003
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001858
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001859
IAO_0000115: A pre-B-I cell is a precursor B cell that expresses CD34 and surrogate immunoglobulin light chain (VpreB , Lambda 5 (mouse)/14.1 (human)) on the cell surface, and TdT, Rag1,and Rag2 intracellularly. Cell type carries a D-JH DNA rearrangement, and lacks expression of immunglobulin heavy chain protein.
has exact synonym: pre-BI cell
has related synonym: pro-B cell (Philadelphia nomenclature)

large pre-B-II cell
type: Class
equivalent class: Class
  intersection of: pre-B-II cell
  intersection of: Restriction
    on property: lacks_part
    some values from: PR_000003457
  intersection of: Restriction
    on property: lacks_part
    some values from: PR_000003460
  intersection of: Restriction
    on property: RO_0000056
    some values from: GO_0046651
subclass of: pre-B-II cell
subclass of: Restriction
  on property: lacks_part
  some values from: PR_000003457
subclass of: Restriction
  on property: lacks_part
  some values from: PR_000003460
subclass of: Restriction
  on property: RO_0000056
  some values from: GO_0046651
IAO_0000115: A large pre-B-II cell is a pre-B-II cell that is proliferating and is Rag1-negative and Rag2-negative.
has broad synonym: large pre-B cell
has exact synonym: large pre-BII cell

T1 B cell
type: Class
equivalent class: Class
  intersection of: transitional stage B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0071738
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001318
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001338
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001880
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002037
subclass of: transitional stage B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0071738
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001318
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001338
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001880
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002037
IAO_0000115: A transitional stage B cell that migrates from the bone marrow into the peripheral circulation, and finally to the spleen. This cell type has the phenotype surface IgM-positive, surface IgD-negative, CD21-negative, CD23-negative, and CD62L-negative, and CD93-positive. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-negative.
has exact synonym: T1 B lymphocyte
has exact synonym: T1 B-cell
has exact synonym: T1 B-lymphocyte
has exact synonym: transitional stage 1 B cell

T2 B cell
type: Class
equivalent class: Class
  intersection of: transitional stage B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001318
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071738
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071753
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001338
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001880
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002037
subclass of: transitional stage B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001318
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0071738
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001338
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001880
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002037
subclass of: Restriction
  on property: RO_0002202
  some values from: T1 B cell
IAO_0000115: A transitional stage B cell that has the phenotype surface IgM-positive, surface IgD-postive, CD21-positive, CD23-positive, CD62L-negative, CD93-positive and is located in the splenic B follicles. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-positive.
has exact synonym: T2 B lymphocyte
has exact synonym: T2 B-cell
has exact synonym: T2 B-lymphocyte
has exact synonym: transitional stage 2 B cell

T3 B cell
type: Class
equivalent class: Class
  intersection of: transitional stage B cell
  intersection of: Restriction
    on property: RO_0000056
    some values from: GO_0002515
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071738
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071753
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001318
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001338
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001880
subclass of: transitional stage B cell
subclass of: Restriction
  on property: RO_0000056
  some values from: GO_0002515
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0071738
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001318
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001338
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001880
subclass of: Restriction
  on property: RO_0002202
  some values from: T2 B cell
IAO_0000115: A transitional stage B cell that expresses surface IgM and IgD, and CD62L. This cell type appears to be an anergic B cell that does not proliferate upon BCR signaling, is found in the spleen and lymph nodes, and has the phenotype surface IgM-positive, surface IgD-positive, CD21-positive, CD23-positive, CD62L-positive, and CD93-positive. This cell type has also been described as IgM-low, CD19-positive, B220-positive, AA4-positive, and CD23-positive (i.e. this cell-type is distinguished from T2 cells by surface expression of IgM).
has exact synonym: An1 B cell
has exact synonym: T3 B lymphocyte
has exact synonym: T3 B-cell
has exact synonym: T3 B-lymphocyte
has exact synonym: transitional stage 3 B cell

Bm1 B cell
type: Class
equivalent class: Class
  intersection of: follicular B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001408
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001880
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071738
subclass of: follicular B cell
subclass of: fraction F mature B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001408
IAO_0000115: A follicular B cell that is IgD-positive, CD23-negative, and CD38-negative. This naive cell type is activated in the extrafollicular areas through interaction with interdigitating dendritic cells and antigen-specific CD4-positive T cells.
has exact synonym: Bm1 B lymphocyte
has exact synonym: Bm1 B-cell
has exact synonym: Bm1 B-lymphocyte

Bm2 B cell
type: Class
equivalent class: Class
  intersection of: follicular B cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071738
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001408
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001880
subclass of: follicular B cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001408
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001880
subclass of: Restriction
  on property: RO_0002202
  some values from: Bm1 B cell
IAO_0000115: A follicular B cell that is IgD-positive and CD23-positive and CD38-positive. This naive cell type is activated in the extrafollicular areas via interaction with dendritic cells and antigen specific T cells.
has exact synonym: Bm2 B lymphocyte
has exact synonym: Bm2 B-cell
has exact synonym: Bm2 B-lymphocyte

Bm3-delta B cell
type: Class
equivalent class: Class
  intersection of: germinal center B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0071753
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071738
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001408
subclass of: germinal center B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0071753
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0071738
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001408
subclass of: Restriction
  on property: RO_0002202
  some values from: Bm3 B cell
IAO_0000115: A germinal center B cell that develops from a Bm3 B cell. This cell has the phenotype IgM-negative, IgD-positive, and CD38-positive.
has exact synonym: Bm3-delta B lymphocyte
has exact synonym: Bm3-delta B-cell
has exact synonym: Bm3-delta B-lymphocyte

Bm2' B cell
type: Class
equivalent class: Class
  intersection of: germinal center B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001880
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071738
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001408
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002634
subclass of: germinal center B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001880
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0071738
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001408
subclass of: Restriction
  on property: RO_0002202
  some values from: Bm2 B cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002634
IAO_0000115: A germinal center B cell that founds a germinal center, and has the phenotype IgD-positive, CD38-positive, and CD23-negative.
has exact synonym: Bm2' B lymphocyte
has exact synonym: Bm2' B-cell
has exact synonym: Bm2-prime B cell
has exact synonym: Bm2-prime B-lymphocyte
has related synonym: germinal center founder cell

Bm3 B cell
type: Class
equivalent class: Class
  intersection of: germinal center B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0071738
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001408
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000003516
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0016446
subclass of: germinal center B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0071738
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001408
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000003516
subclass of: Restriction
  on property: RO_0002202
  some values from: Bm2' B cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0016446
IAO_0000115: A germinal center B cell that is rapidly dividing and has the phenotype IgD-negative, CD38-positive, and CD77-positive. Somatic hypermutation of the immunoglobulin V gene region can occur during proliferation of this cell type.
has exact synonym: Bm3 B lymphocyte
has exact synonym: Bm3 B-cell
has exact synonym: Bm3 B-lymphocyte
has related synonym: centroblast

Bm4 B cell
type: Class
equivalent class: Class
  intersection of: germinal center B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0071738
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000003516
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001408
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0016446
subclass of: germinal center B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0071738
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000003516
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001408
subclass of: Restriction
  on property: RO_0002202
  some values from: Bm3-delta B cell
subclass of: Restriction
  on property: RO_0002353
  some values from: GO_0016446
IAO_0000115: A germinal center B cell that has the phenotype CD77-negative, IgD-negative, and CD38-positive. These cells have undergone somatic mutation of the B cell receptor.
has exact synonym: Bm4 B lymphocyte
has exact synonym: Bm4 B-cell
has exact synonym: Bm4 B-lymphocyte
has related synonym: centrocyte

Bm5 B cell
type: Class
equivalent class: Class
  intersection of: memory B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0071738
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0002314
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0016446
subclass of: IgD-negative memory B cell
subclass of: Restriction
  on property: RO_0002202
  some values from: Bm4 B cell
subclass of: Restriction
  on property: RO_0002353
  some values from: GO_0002314
subclass of: Restriction
  on property: RO_0002353
  some values from: GO_0016446
IAO_0000115: A memory B cell arising in the germinal center that is IgD-negative and has undergone somatic mutation of the variable region of the immunoglobulin heavy and light chain genes.
has exact synonym: Bm5 B lymphocyte
has exact synonym: Bm5 B-cell
has exact synonym: Bm5 B-lymphocyte

Be cell
type: Class
equivalent class: Class
  intersection of: mature B cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001289
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0001816
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0043370
subclass of: mature B cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001289
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0001816
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0043370
IAO_0000115: A mature B cell that produces cytokines that can influence CD4 T cell differentiation.
has exact synonym: B effector cell
has exact synonym: effector B cell
has exact synonym: effector B lymphocyte
has exact synonym: effector B-cell
has exact synonym: effector B-lymphocyte

unswitched memory B cell
type: Class
equivalent class: Class
  intersection of: memory B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0071735
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0071742
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0071745
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001935
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071738
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071753
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001963
subclass of: memory B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0071735
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0071742
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0071745
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0071738
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0071753
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001963
subclass of: Restriction
  on property: RO_0002202
  some values from: plasmablast
IAO_0000115: An unswitched memory B cell is a memory B cell that has the phenotype IgM-positive, IgD-positive, CD27-positive, CD138-negative, IgG-negative, IgE-negative, and IgA-negative.
has broad synonym: IgD+ memory B cell
has exact synonym: non-class-switched memory B cell
has exact synonym: unswitched memory B lymphocyte
has exact synonym: unswitched memory B-cell
has exact synonym: unswitched memory B-lymphocyte

IgM memory B cell
type: Class
equivalent class: Class
  intersection of: memory B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0071738
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071753
subclass of: IgD-negative memory B cell
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0071753
IAO_0000115: An IgM memory B cell is an unswitched memory B cell with the phenotype IgM-positive and IgD-negative.
has exact synonym: IgM memory B lymphocyte
has exact synonym: IgM memory B-cell
has exact synonym: IgM memory B-lymphocyte
has exact synonym: memory IgM B cell
has exact synonym: memory IgM B lymphocyte
has exact synonym: memory IgM B-cell
has exact synonym: memory IgM B-lymphocyte

class switched memory B cell
type: Class
equivalent class: Class
  intersection of: memory B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0071753
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001963
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0045190
subclass of: memory B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0071753
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001963
subclass of: Restriction
  on property: RO_0002202
  some values from: unswitched memory B cell
subclass of: Restriction
  on property: RO_0002353
  some values from: GO_0045190
IAO_0000115: A class switched memory B cell is a memory B cell that has undergone Ig class switching and therefore is IgM-negative on the cell surface. These cells are CD27-positive and have either IgG, IgE, or IgA on the cell surface.
has exact synonym: class switched memory B lymphocyte
has exact synonym: class switched memory B-cell
has exact synonym: class switched memory B-lymphocyte

IgA memory B cell
type: Class
equivalent class: Class
  intersection of: class switched memory B cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071745
subclass of: class switched memory B cell
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0071745
IAO_0000115: A class switched memory B cell that expresses IgA.
has exact synonym: IgA memory B lymphocyte
has exact synonym: IgA memory B-cell
has exact synonym: IgA memory B-lymphocyte
has exact synonym: memory IgA B cell
has exact synonym: memory IgA B lymphocyte
has exact synonym: memory IgA B-cell
has exact synonym: memory IgA B-lymphocyte

long lived plasma cell
type: Class
equivalent class: Class
  intersection of: plasma cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0019814
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0042613
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001408
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001208
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001935
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001002
subclass of: plasma cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001408
subclass of: Restriction
  on property: RO_0002202
  some values from: short lived plasma cell
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001208
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001935
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001002
IAO_0000115: A fully differentiated plasma cell that lives for years, as opposed to months, secretes immunoglobulin, and has the phenotype weakly CD19-positive, CD20-negative, CD38-negative, strongly CD138-positive, MHC Class II-negative, surface immunoglobulin-negative, IgD-negative, and strongly CXCR4-positive. The majority of these cells of this type reside in the bone marrow.

short lived plasma cell
type: Class
equivalent class: Class
  intersection of: plasma cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001604
subclass of: plasma cell
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0001604
IAO_0000115: A fully differentiated plasma cell that lives for months.

IgA short lived plasma cell
type: Class
equivalent class: Class
  intersection of: short lived plasma cell
  intersection of: Restriction
    on property: RO_0003000
    some values from: GO_0071746
subclass of: short lived plasma cell
subclass of: Restriction
  on property: RO_0003000
  some values from: GO_0071746
IAO_0000115: A short lived plasma cell that secretes IgA. These cells may be found in the bone marrow as well as in the mucosal immune system.

IgG short lived plasma cell
type: Class
equivalent class: Class
  intersection of: short lived plasma cell
  intersection of: Restriction
    on property: RO_0003000
    some values from: GO_0071736
subclass of: short lived plasma cell
subclass of: Restriction
  on property: RO_0003000
  some values from: GO_0071736
IAO_0000115: A short lived plasma cell that secretes IgG.

IgM short lived plasma cell
type: Class
equivalent class: Class
  intersection of: short lived plasma cell
  intersection of: Restriction
    on property: RO_0003000
    some values from: GO_0071754
subclass of: short lived plasma cell
subclass of: Restriction
  on property: RO_0003000
  some values from: GO_0071754
IAO_0000115: A short lived plasma cell that secretes IgM.

IgG memory B cell
type: Class
equivalent class: Class
  intersection of: class switched memory B cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071735
subclass of: class switched memory B cell
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0071735
IAO_0000115: An IgG memory B cell is a class switched memory B cell that is class switched and expresses IgG on the cell surface.
has exact synonym: IgG memory B lymphocyte
has exact synonym: IgG memory B-cell
has exact synonym: IgG memory B-lymphocyte
has exact synonym: memory IgG B cell
has exact synonym: memory IgG B lymphocyte
has exact synonym: memory IgG B-cell
has exact synonym: memory IgG B-lymphocyte

plasmablast
type: Class
equivalent class: Class
  intersection of: mature B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001935
  intersection of: Restriction
    on property: RO_0003000
    some values from: GO_0042571
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001408
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001963
subclass of: mature B cell
subclass of: antibody secreting cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001935
subclass of: Restriction
  on property: RO_0002202
  some values from: mature B cell
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001408
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001963
IAO_0000115: An activated mature (naive or memory) B cell that is secreting immunoglobulin, typified by being CD27-positive, CD38-positive, CD138-negative.
has broad synonym: CD20-negative B cell
has exact synonym: CD27-positive, CD38-positive, CD20-negative B cell

double negative memory B cell
type: Class
equivalent class: Class
  intersection of: memory B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0071738
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001963
subclass of: IgD-negative memory B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001963
IAO_0000115: A memory B cell with the phenotype IgD-negative and CD27-negative.
has exact synonym: dn memory B cell
has exact synonym: dn memory B lymphocyte
has exact synonym: dn memory B-cell
has exact synonym: dn memory B-lymphocyte
has exact synonym: double negative memory B lymphocyte
has exact synonym: double negative memory B-cell
has exact synonym: double negative memory B-lymphocyte

IgG plasmablast
type: Class
equivalent class: Class
  intersection of: plasmablast
  intersection of: Restriction
    on property: RO_0003000
    some values from: GO_0071736
subclass of: plasmablast
subclass of: Restriction
  on property: RO_0003000
  some values from: GO_0071736
IAO_0000115: A plasmablast that secretes IgG.

IgM plasmablast
type: Class
equivalent class: Class
  intersection of: plasmablast
  intersection of: Restriction
    on property: RO_0003000
    some values from: GO_0071754
subclass of: plasmablast
subclass of: Restriction
  on property: RO_0003000
  some values from: GO_0071754
IAO_0000115: A plasmablast that secretes IgM.

IgA plasmablast
type: Class
equivalent class: Class
  intersection of: plasmablast
  intersection of: Restriction
    on property: RO_0003000
    some values from: GO_0071746
subclass of: plasmablast
subclass of: Restriction
  on property: RO_0003000
  some values from: GO_0071746
IAO_0000115: A plasmablast that secretes IgA.

IgG plasma cell
type: Class
equivalent class: Class
  intersection of: long lived plasma cell
  intersection of: Restriction
    on property: RO_0003000
    some values from: GO_0071736
subclass of: long lived plasma cell
subclass of: Restriction
  on property: RO_0003000
  some values from: GO_0071736
IAO_0000115: A fully differentiated plasma cell that secretes IgG.

IgM plasma cell
type: Class
equivalent class: Class
  intersection of: long lived plasma cell
  intersection of: Restriction
    on property: RO_0003000
    some values from: GO_0071754
subclass of: long lived plasma cell
subclass of: Restriction
  on property: RO_0003000
  some values from: GO_0071754
IAO_0000115: A fully differentiated plasma cell that secretes IgM.

IgA plasma cell
type: Class
equivalent class: Class
  intersection of: long lived plasma cell
  intersection of: Restriction
    on property: RO_0003000
    some values from: GO_0071746
subclass of: long lived plasma cell
subclass of: Restriction
  on property: RO_0003000
  some values from: GO_0071746
IAO_0000115: A fully differentiated plasma cell that secretes IgA.

hematopoietic cell
type: Class
subclass of: cell
IAO_0000115: A cell of a hematopoietic lineage.
has exact synonym: haematopoietic cell
has exact synonym: haemopoietic cell
has exact synonym: hemopoietic cell

CD11c-low plasmacytoid dendritic cell
type: Class
equivalent class: Class
  intersection of: plasmacytoid dendritic cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001014
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002978
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001013
subclass of: plasmacytoid dendritic cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001014
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002978
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001013
IAO_0000115: CD11c-low plasmacytoid dendritic cell is a leukocyte that is CD11c-low, CD45R-positive, GR1-positive and CD11b-negative.

conventional dendritic cell
type: Class
equivalent class: Class
  intersection of: dendritic cell
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001013
subclass of: dendritic cell
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001013
IAO_0000115: Conventional dendritic cell is a dendritic cell that is CD11c-high.
has broad synonym: interdigitating cell
has broad synonym: veiled cell
has exact synonym: DC1
has exact synonym: cDC
has exact synonym: dendritic reticular cell
has exact synonym: type 1 DC

immature CD11c-low plasmacytoid dendritic cell
type: Class
equivalent class: Class
  intersection of: CD11c-low plasmacytoid dendritic cell
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001412
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001438
subclass of: myeloid leukocyte
subclass of: CD11c-low plasmacytoid dendritic cell
subclass of: Restriction
  on property: RO_0002202
  some values from: common dendritic progenitor
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001412
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001438
IAO_0000115: Immature CD11c-low plasmacytoid dendritic cell is a CD11c-low plasmacytoid dendritic cell that is CD80-low and CD86-low.

mature CD11c-low plasmacytoid dendritic cell
type: Class
equivalent class: Class
  intersection of: CD11c-low plasmacytoid dendritic cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001310
  intersection of: Restriction
    on property: RO_0015015
    some values from: GO_0042613
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001412
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001438
subclass of: myeloid leukocyte
subclass of: CD11c-low plasmacytoid dendritic cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001310
subclass of: Restriction
  on property: RO_0002202
  some values from: immature CD11c-low plasmacytoid dendritic cell
subclass of: Restriction
  on property: RO_0015015
  some values from: GO_0042613
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001412
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001438
IAO_0000115: Mature CD11c-low plasmacytoid dendritic cell is a CD11c-low plasmacytoid dendritic cell that is CD83-high and is CD80-positive, CD86-positive, and MHCII-positive.

CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor
type: Class
equivalent class: Class
  union of: CD34-positive, CD38-positive common lymphoid progenitor
  union of: CD34-positive, CD38-positive common myeloid progenitor
subclass of: hematopoietic oligopotent progenitor cell, lineage-negative
has broad synonym: CD71-positive common myeloid precursor OR CD7-negative lymphoid precursor OR CD7-positive lymphoid

Kit and Sca1-positive hematopoietic stem cell
type: Class
equivalent class: Class
  intersection of: hematopoietic stem cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001014
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001308
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001869
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001896
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002977
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002981
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001833
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002065
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002979
subclass of: hematopoietic stem cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001014
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001308
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001869
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001896
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002977
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001833
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002065
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002979
disjoint with: CD34-positive, CD38-negative hematopoietic stem cell
IAO_0000115: A hematopoietic stem cell that has plasma membrane part Kit-positive, SCA-1-positive, CD150-positive and CD34-negative.
has exact synonym: LSK stem cell
has exact synonym: Sca1-positive hematopoietic stem cell

CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor
type: Class
equivalent class: Class
  union of: granulocyte monocyte progenitor cell
  union of: CD7-negative lymphoid progenitor cell
subclass of: hematopoietic oligopotent progenitor cell, lineage-negative

CD115-positive monocyte OR common dendritic progenitor
type: Class
equivalent class: Class
  union of: CD115-positive monocyte
  union of: common dendritic progenitor
subclass of: hematopoietic lineage restricted progenitor cell

CD34-positive, CD38-positive common lymphoid progenitor
type: Class
equivalent class: Class
  intersection of: common lymphoid progenitor
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001003
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001015
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001408
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001898
subclass of: common lymphoid progenitor
subclass of: CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001003
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001015
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001408
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001898
subclass of: Restriction
  on property: RO_0002202
  some values from: CD34-positive, CD38-negative multipotent progenitor cell
disjoint with: Kit-positive, Sca1-positive common lymphoid progenitor
IAO_0000115: A common lymphoid progenitor that is CD10-positive, CD45RA-positive, CD34-positive and CD38-positive.
has exact synonym: CD10-positive common lymphocyte precursor
has exact synonym: CD10-positive common lymphocyte progenitor
has exact synonym: CD10-positive common lymphoid precursor

CD115-positive monocyte
type: Class
equivalent class: Class
  intersection of: monocyte
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001012
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002062
subclass of: monocyte
subclass of: myeloid lineage restricted progenitor cell
subclass of: CD115-positive monocyte OR common dendritic progenitor
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001012
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002062
subclass of: Restriction
  on property: RO_0002202
  some values from: CD34-positive, CD38-positive granulocyte monocyte progenitor
IAO_0000115: CD115-positive monocyte is a monocyte that is CD115-positive and CD11b-positive.

Kit-positive, CD34-positive common myeloid progenitor
type: Class
equivalent class: Class
  intersection of: common myeloid progenitor, CD34-positive
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001869
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002979
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002065
  intersection of: Restriction
    on property: RO_0015016
    some values from: GO_0033001
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001481
subclass of: CD117-positive common myeloid progenitor OR CD217-positive common lymphoid progenitor
subclass of: common myeloid progenitor, CD34-positive
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001869
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002979
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002065
subclass of: Restriction
  on property: RO_0002202
  some values from: Slamf1-negative multipotent progenitor cell
subclass of: Restriction
  on property: RO_0015016
  some values from: GO_0033001
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001481
disjoint with: CD34-positive, CD38-positive common myeloid progenitor
IAO_0000115: A common myeloid progenitor that is Kit-positive and CD34-positive, Il7ra-negative, and is SCA1-low and Fcgr2-low and Fcgr3-low.
has broad synonym: CD117-positive common myeloid precursor

CD34-positive, CD38-negative hematopoietic stem cell
type: Class
equivalent class: Class
  intersection of: hematopoietic stem cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001408
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001483
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001892
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001945
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001003
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001786
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001809
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001843
subclass of: hematopoietic stem cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001408
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001483
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001892
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001945
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001003
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001786
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001809
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001843
IAO_0000115: CD133-positive hematopoietic stem cell is a hematopoietic stem cell that is CD34-positive, CD90-positive, and CD133-positive.
has exact synonym: CD133-positive hematopoietic stem cell

Kit-positive, Sca1-positive common lymphoid progenitor
type: Class
equivalent class: Class
  intersection of: common lymphoid progenitor
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001014
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001869
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001963
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002001
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002037
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000002065
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000002979
subclass of: common lymphoid progenitor
subclass of: CD117-positive common myeloid progenitor OR CD217-positive common lymphoid progenitor
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001014
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001869
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001963
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002001
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002037
subclass of: Restriction
  on property: RO_0002202
  some values from: early lymphoid progenitor
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000002065
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000002979
IAO_0000115: A common lymphoid progenitor that is Kit-low, FLT3-positive, IL7ralpha-positive, and SCA1-low.
has exact synonym: CD217-positive common lymphocyte precursor
has exact synonym: CD217-positive common lymphocyte progenitor
has exact synonym: CD217-positive common lymphoid precursor

CD34-positive, CD38-positive common myeloid progenitor
type: Class
equivalent class: Class
  intersection of: common myeloid progenitor, CD34-positive
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001015
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001836
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001867
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001898
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001408
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001865
subclass of: CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor
subclass of: common myeloid progenitor, CD34-positive
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001015
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001836
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001867
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001898
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001408
subclass of: Restriction
  on property: RO_0002202
  some values from: CD34-positive, CD38-negative multipotent progenitor cell
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001865
IAO_0000115: A common myeloid progenitor that is CD34-positive, CD38-positive, IL3ra-low, CD10-negative, CD7-negative, CD45RA-negative, and IL-5Ralpha-negative.
has narrow synonym: CD71-positive common myeloid precursor

CD7-negative lymphoid progenitor cell
type: Class
equivalent class: Class
  intersection of: common lymphoid progenitor
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001015
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001836
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001003
subclass of: common lymphoid progenitor
subclass of: CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001015
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001836
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001003
subclass of: Restriction
  on property: RO_0002202
  some values from: CD34-positive, CD38-positive common lymphoid progenitor
IAO_0000115: CD7-negative lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-negative and CD45RA-negative.
has exact synonym: CD7-negative lymphoid precursor

CD7-positive lymphoid progenitor cell
type: Class
equivalent class: Class
  intersection of: common lymphoid progenitor
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001015
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001003
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001836
subclass of: common lymphoid progenitor
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001015
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001003
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001836
subclass of: Restriction
  on property: RO_0002202
  some values from: CD7-negative lymphoid progenitor cell
IAO_0000115: CD7-positive lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-positive and is CD45RA-negative.
has exact synonym: CD7-positive lymphoid precursor

common dendritic progenitor
type: Class
equivalent class: Class
  intersection of: hematopoietic lineage restricted progenitor cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002981
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002001
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002062
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000002065
subclass of: myeloid cell
subclass of: CD115-positive monocyte OR common dendritic progenitor
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002981
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002001
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002062
subclass of: Restriction
  on property: RO_0002202
  some values from: macrophage dendritic cell progenitor
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000002065
IAO_0000115: Common dendritic precursor is a hematopoietic progenitor cell that is CD117-low, CD135-positive, CD115-positive and lacks plasma membrane parts for hematopoietic lineage markers.
has exact synonym: CDP
has exact synonym: common dendritic precursor
has exact synonym: pro-DCs

CD117-positive common myeloid progenitor OR CD217-positive common lymphoid progenitor
type: Class
equivalent class: Class
  union of: Kit-positive, CD34-positive common myeloid progenitor
  union of: Kit-positive, Sca1-positive common lymphoid progenitor
subclass of: hematopoietic oligopotent progenitor cell, lineage-negative

cerebellar granule cell
type: Class
equivalent class: Class
  intersection of: granule cell
  intersection of: Restriction
    on property: RO_0002100
    some values from: UBERON_0002037
subclass of: granule cell
subclass of: CL_2000028
subclass of: UBERON_0004121
subclass of: Restriction
  on property: RO_0002207
  some values from: cerebellar granule cell precursor
IAO_0000115: An excitatory granule cell with a soma located in the granular layer of cerebellar cortex. A mature cerebellar granule cell has short dendrites with a characteristic claw-like appearance and a long axon that ascends to the molecular layer where it bifurcates (except in non-teleost fish, where it does not bifurcate) and extends mediolaterally to form parallel fibers.
has exact synonym: granule cell of the cerebellum

cortical granule cell
type: Class
equivalent class: Class
  intersection of: granule cell
  intersection of: Restriction
    on property: RO_0002100
    some values from: UBERON_0000956
subclass of: granule cell
subclass of: CL_0010012
subclass of: CL_0012001
IAO_0000115: Granule cell that is part of the cerebral cortex.

hippocampal granule cell
type: Class
equivalent class: Class
  intersection of: granule cell
  intersection of: Restriction
    on property: RO_0002100
    some values from: UBERON_0002421
subclass of: cortical granule cell
subclass of: CL_0002608
IAO_0000115: Granule cell with a soma found in the hippocampus.

bone cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001474
subclass of: cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001474
IAO_0000115: A connective tissue cell found in bone.

CD8-positive, CXCR3-positive, alpha-beta regulatory T cell
type: Class
equivalent class: Class
  intersection of: CD8-positive, alpha-beta regulatory T cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000001207
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032613
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032689
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0042130
subclass of: CD8-positive, alpha-beta regulatory T cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000001207
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032613
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032689
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0042130
IAO_0000115: A CD8-positive alpha-beta-positive T cell with the phenotype CXCR3-positive and having suppressor function. They are capable of producing IL-10, suppressing proliferation, and suppressing IFN-gamma production.
has exact synonym: CD8+CXCR3+ T cell
has exact synonym: CD8+CXCR3+ T lymphocyte
has exact synonym: CD8+CXCR3+ T(reg)
has exact synonym: CD8+CXCR3+ T-cell
has exact synonym: CD8+CXCR3+ Treg
has exact synonym: CD8-positive, CXCR3-positive, T(reg)
has exact synonym: CD8-positive, CXCR3-positive, Treg
has exact synonym: CD8-positive, CXCR3-positive, alpha-beta regulatory T lymphocyte
has exact synonym: CD8-positive, CXCR3-positive, alpha-beta regulatory T-cell
has exact synonym: CD8-positive, CXCR3-positive, alpha-beta regulatory T-lymphocyte

T-helper 22 cell
type: Class
equivalent class: Class
  intersection of: CD4-positive helper T cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032626
subclass of: CD4-positive helper T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032626
IAO_0000115: CD4-positive, alpha-beta T cell that produces IL-22.
has exact synonym: T(H)-22 cell
has exact synonym: Th22 T cell
has exact synonym: Th22 T lymphocyte
has exact synonym: Th22 T-cell
has exact synonym: Th22 T-lymphocyte
has exact synonym: Th22 cell
has exact synonym: helper T cell type 22

effector CD4-positive, alpha-beta T cell
type: Class
equivalent class: Class
  intersection of: effector T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001203
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000025402
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0042105
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001004
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001015
subclass of: CD4-positive, alpha-beta T cell
subclass of: effector T cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001203
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001015
IAO_0000115: A CD4-positive, alpha-beta T cell with the phenotype CCR7-negative, CD45RA-positive.
has broad synonym: effector CD4+ T cell
has exact synonym: effector CD4-positive, alpha-beta T lymphocyte
has exact synonym: effector CD4-positive, alpha-beta T-cell
has exact synonym: effector CD4-positive, alpha-beta T-lymphocyte

effector CD8-positive, alpha-beta T cell
type: Class
equivalent class: Class
  intersection of: effector T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001203
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0042105
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001015
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000025402
subclass of: CD8-positive, alpha-beta T cell
subclass of: effector T cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001203
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001015
IAO_0000115: A CD8-positive, alpha-beta T cell with the phenotype CCR7-negative, CD45RA-positive.
has broad synonym: effector CD8+ T cell
has exact synonym: effector CD8-positive, alpha-beta T lymphocyte
has exact synonym: effector CD8-positive, alpha-beta T-cell
has exact synonym: effector CD8-positive, alpha-beta T-lymphocyte

CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell
type: Class
equivalent class: Class
  intersection of: CD4-positive, alpha-beta T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001202
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001207
subclass of: CD4-positive, alpha-beta T cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001202
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001207
IAO_0000115: A CD4-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-negative.
has broad synonym: non-Th1/Th17 CD4+ T cell
has exact synonym: CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T lymphocyte
has exact synonym: CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T-cell
has exact synonym: CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T-lymphocyte

CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell
type: Class
equivalent class: Class
  intersection of: CD8-positive, alpha-beta T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001202
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001207
subclass of: CD8-positive, alpha-beta T cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001202
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001207
IAO_0000115: A CD8-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-negative.
has broad synonym: non-Tc1/Tc17 CD8+ T cell
has exact synonym: CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T lymphocyte
has exact synonym: CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T-cell
has exact synonym: CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T-lymphocyte

IgD-negative memory B cell
type: Class
equivalent class: Class
  intersection of: memory B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0071738
subclass of: memory B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0071738
IAO_0000115: A memory B cell that lacks expression of surface IgD.
has exact synonym: IgD- memory B cell

CD14-positive monocyte
type: Class
equivalent class: Class
  intersection of: monocyte
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001889
subclass of: monocyte
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001889
IAO_0000115: A monocyte that expresses CD14 and is negative for the lineage markers CD3, CD19, and CD20.
has narrow synonym: monocyte

CD14-positive, CD16-low monocyte
type: Class
equivalent class: Class
  intersection of: intermediate monocyte
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001889
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001483
subclass of: intermediate monocyte
subclass of: CD14-positive, CD16-positive monocyte
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001483
IAO_0000115: An intermediate monocyte that is CD14-positive and with low amounts of CD16.
has exact synonym: intermediate monocyte, human

common myeloid progenitor, CD34-positive
type: Class
equivalent class: Class
  intersection of: common myeloid progenitor
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000001944
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000005307
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000007857
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000007858
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001003
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002573
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0043011
subclass of: common myeloid progenitor
subclass of: CL_0011026
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000001944
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000005307
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000007857
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000007858
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001003
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0043011
IAO_0000115: A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata1, Gata2, C/EBPa, and Pu.1.
has exact synonym: common myeloid precursor, CD34-positive
has related synonym: CFU-GEMM
has related synonym: CFU-S
has related synonym: CMP
has related synonym: colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte
has related synonym: multipotential myeloid stem cell
has related synonym: myeloid stem cell
has related synonym: pluripotent stem cell (bone marrow)

hematopoietic oligopotent progenitor cell, lineage-negative
type: Class
equivalent class: Class
  intersection of: hematopoietic oligopotent progenitor cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002981
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001401
subclass of: hematopoietic oligopotent progenitor cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002981
IAO_0000115: A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers.

innate lymphoid cell
type: Class
equivalent class: Class
  intersection of: lymphocyte
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0001816
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0045087
subclass of: lymphocyte
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0001816
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0045087
IAO_0000115: A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses.

erythroid progenitor cell, mammalian
type: Class
equivalent class: Class
  intersection of: erythroid progenitor cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001945
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030218
subclass of: erythroid progenitor cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001945
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030218
IAO_0000115: A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative).
has related synonym: BFU-E
has related synonym: CFU-E
has related synonym: blast forming unit erythroid
has related synonym: burst forming unit erythroid
has related synonym: colony forming unit erythroid
has related synonym: erythroid stem cell

group 1 innate lymphoid cell
type: Class
equivalent class: Class
  intersection of: innate lymphoid cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032609
subclass of: innate lymphoid cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032609
IAO_0000115: An innate lymphoid cell that is capable of producing the type 1 cytokine IFN-gamma, but not Th2 or Th17 cell-associated cytokines.

group 2 innate lymphoid cell
type: Class
equivalent class: Class
  intersection of: innate lymphoid cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032634
subclass of: innate lymphoid cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032634
IAO_0000115: An innate lymphoid cell that is capable of producing T-helper 2-cell associated cytokines upon stimulation.
has exact synonym: ILC2
has exact synonym: natural helper cell
has exact synonym: nuocyte

group 3 innate lymphoid cell
type: Class
equivalent class: Class
  intersection of: innate lymphoid cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000003455
subclass of: innate lymphoid cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000003455
IAO_0000115: An innate lymphoid cell that constituitively expresses RORgt and is capable of expressing IL17A and/or IL-22.
has exact synonym: ILC3

immature innate lymphoid cell
type: Class
equivalent class: Class
  intersection of: innate lymphoid cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001501
subclass of: innate lymphoid cell
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0001501
IAO_0000115: An innate lyphoid cell with an immature phenotype.
has exact synonym: immature ILC

lymphocyte of B lineage, CD19-positive
type: Class
equivalent class: Class
  intersection of: lymphocyte of B lineage
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001002
  intersection of: Restriction
    on property: RO_0002162
    some values from: NCBITaxon_40674
subclass of: lymphocyte of B lineage
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001002
subclass of: Restriction
  on property: RO_0002162
  some values from: NCBITaxon_40674
IAO_0000115: A lymphocyte of B lineage that is CD19-positive.

B cell, CD19-positive
type: Class
equivalent class: Class
  intersection of: lymphocyte of B lineage, CD19-positive
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001002
  intersection of: Restriction
    on property: RO_0002162
    some values from: NCBITaxon_40674
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0019724
subclass of: B cell
subclass of: lymphocyte of B lineage, CD19-positive
IAO_0000115: A B cell that is CD19-positive.
has exact synonym: B lymphocyte, CD19-positive
has exact synonym: B-cell, CD19-positive
has exact synonym: B-lymphocyte, CD19-positive
has exact synonym: CD19+ B cell
has exact synonym: CD19-positive B cell

CD86-positive plasmablast
type: Class
equivalent class: Class
  intersection of: plasmablast
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001412
subclass of: plasmablast
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001412
IAO_0000115: A plasmablast that is CD86-positive.
has broad synonym: CD86-positive, CD20-negative plasmablast
has exact synonym: CD86+ plasmablast

visual pigment cell (sensu Nematoda and Protostomia)
type: Class
subclass of: visual pigment cell
subclass of: pigment cell (sensu Nematoda and Protostomia)

Kit-positive erythroid progenitor cell
type: Class
equivalent class: Class
  intersection of: erythroid progenitor cell, mammalian
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0033001
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001833
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001865
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001869
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002979
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000009127
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001345
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002065
subclass of: erythroid progenitor cell, mammalian
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0033001
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001833
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001865
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001869
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002979
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000009127
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001345
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002065
subclass of: Restriction
  on property: RO_0002202
  some values from: Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell
IAO_0000115: An erythroid progenitor cell is Kit-positive, Ly6A-negative, CD41-negative, CD127-negative, and CD123-negative. This cell type is also described as being lin-negative, Kit-positive, CD150-negative, CD41-negative, CD105-positive, and FcgR-negative.
has exact synonym: c- Kit-positive erythroid progenitor cell

CD34-positive, CD38-positive granulocyte monocyte progenitor
type: Class
equivalent class: Class
  intersection of: granulocyte monocyte progenitor cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001003
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001408
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001865
subclass of: granulocyte monocyte progenitor cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001003
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001408
subclass of: Restriction
  on property: RO_0002202
  some values from: CD34-positive, CD38-positive common myeloid progenitor
IAO_0000115: A granulocyte monocyte progenitor is CD34-positive, CD38-positive, IL-3receptor-alpha-positive and is CD45RA-negative.

Kit-positive granulocyte monocyte progenitor
type: Class
equivalent class: Class
  intersection of: granulocyte monocyte progenitor cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001206
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001843
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001869
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002979
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001003
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002065
  intersection of: Restriction
    on property: RO_0015015
    some values from: GO_0033001
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001479
subclass of: granulocyte monocyte progenitor cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001206
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001843
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001869
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002979
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001003
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002065
subclass of: Restriction
  on property: RO_0002202
  some values from: Kit-positive, CD34-positive common myeloid progenitor
subclass of: Restriction
  on property: RO_0015015
  some values from: GO_0033001
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001479
IAO_0000115: A granulocyte monocyte progenitor that is Kit-positive, CD34-positive, Fc-gamma receptor II/II-positive, and is Sca-1-negative, Il7ra-negative, Cxc3r1-negative, and CD90-negative.

CD34-positive, GlyA-negative erythroid progenitor cell
type: Class
equivalent class: Class
  intersection of: erythroid progenitor cell, mammalian
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001460
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001003
subclass of: erythroid progenitor cell, mammalian
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001460
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001003
subclass of: Restriction
  on property: RO_0002202
  some values from: CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell
IAO_0000115: An erythroid progenitor cell that is CD34-positive and is GlyA-negative.

CD34-negative, GlyA-negative proerythroblast
type: Class
equivalent class: Class
  intersection of: proerythroblast
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001003
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001460
subclass of: proerythroblast
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001003
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001460
subclass of: Restriction
  on property: RO_0002202
  some values from: CD34-positive, GlyA-negative erythroid progenitor cell
IAO_0000115: A proerythoblast that is CD34-negative and GlyA-negative.

CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell
type: Class
equivalent class: Class
  intersection of: megakaryocyte-erythroid progenitor cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001015
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001865
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001003
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001408
subclass of: megakaryocyte-erythroid progenitor cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001015
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001865
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001003
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001408
IAO_0000115: A megakaryocyte erythroid progenitor cell is CD34-positive, CD38-positive and is IL3-receptor alpha-negative and CD45RA-negative.

Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell
type: Class
equivalent class: Class
  intersection of: megakaryocyte-erythroid progenitor cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001003
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001479
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001843
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001869
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002979
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002065
  intersection of: Restriction
    on property: RO_0015016
    some values from: GO_0033001
subclass of: megakaryocyte-erythroid progenitor cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001003
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001479
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001843
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001869
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002979
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002065
subclass of: Restriction
  on property: RO_0015016
  some values from: GO_0033001
IAO_0000115: A megakaryocyte erythroid progenitor cell that is Kit-positive and is Sca1-negative, CD34-negative, CD90-negative, IL7r-alpha-negative and Fcgr II/III-low.

Kit-low, CD34-positive eosinophil progenitor cell
type: Class
equivalent class: Class
  intersection of: eosinophil progenitor cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002979
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001003
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001867
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000002065
subclass of: eosinophil progenitor cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002979
subclass of: Restriction
  on property: RO_0002202
  some values from: Kit-positive granulocyte monocyte progenitor
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000002065
IAO_0000115: A lineage marker-negative, CD34-positive, IL5r-alpha-positive, and Sca1-negative eosinophil progenitor cell.

CD34-positive, CD38-positive eosinophil progenitor cell
type: Class
equivalent class: Class
  intersection of: eosinophil progenitor cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001015
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001408
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001865
subclass of: eosinophil progenitor cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001015
subclass of: Restriction
  on property: RO_0002202
  some values from: CD34-positive, CD38-positive granulocyte monocyte progenitor
IAO_0000115: A lineage marker-negative, CD34-positive, CD38-positive, IL3r-alpha-positive, IL5r-alpha-positive, and CD45RA-negative eosinophil progenitor cell.

macrophage dendritic cell progenitor
type: Class
equivalent class: Class
  intersection of: hematopoietic oligopotent progenitor cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030224
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0043011
subclass of: myeloid cell
subclass of: hematopoietic oligopotent progenitor cell
subclass of: CL_0011026
subclass of: Restriction
  on property: RO_0002202
  some values from: granulocyte monocyte progenitor cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030224
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0043011
IAO_0000115: A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages.
has exact synonym: MDP

pre-conventional dendritic cell
type: Class
equivalent class: Class
  intersection of: hematopoietic lineage restricted progenitor cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0042613
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001012
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001083
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001889
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002978
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002981
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001013
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001968
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002001
subclass of: myeloid cell
subclass of: hematopoietic lineage restricted progenitor cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0042613
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001012
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001083
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001889
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002978
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002981
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001013
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001968
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002001
subclass of: Restriction
  on property: RO_0002202
  some values from: common dendritic progenitor
IAO_0000115: A lin-negative, MHC-II-negative, CD11c-positive, FLT3-positive cell with intermediate expression of SIRP-alpha.

Kit-positive macrophage dendritic cell progenitor
type: Class
equivalent class: Class
  intersection of: macrophage dendritic cell progenitor
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001206
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002001
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002062
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000002065
subclass of: macrophage dendritic cell progenitor
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001206
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002001
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002062
subclass of: Restriction
  on property: RO_0002202
  some values from: Kit-positive granulocyte monocyte progenitor
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000002065
IAO_0000115: A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages. Marker for this cell is Kit-high, CD115-positive, CD135-positive, Cx3cr1-positive, and is Il7ra-negative.
has exact synonym: murine MDP

Kit-low proerythroblast
type: Class
equivalent class: Class
  intersection of: proerythroblast
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001869
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002979
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002981
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001945
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000002065
subclass of: proerythroblast
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001869
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002979
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002981
subclass of: Restriction
  on property: RO_0002202
  some values from: Kit-positive erythroid progenitor cell
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001945
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000002065
IAO_0000115: A proerythoblast that is Kit-low, Lyg76-positive, and CD71-positive.

GlyA-positive basophilic erythroblast
type: Class
equivalent class: Class
  intersection of: basophilic erythroblast
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001003
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001460
subclass of: basophilic erythroblast
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001003
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001460
subclass of: Restriction
  on property: RO_0002202
  some values from: CD34-negative, GlyA-negative proerythroblast
IAO_0000115: A basophilic erythroblast that is GlyA-positive.

Kit-negative, Ly-76 high basophilic erythroblast
type: Class
equivalent class: Class
  intersection of: basophilic erythroblast
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001869
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002065
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002979
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000002981
subclass of: basophilic erythroblast
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001869
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002065
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002979
subclass of: Restriction
  on property: RO_0002202
  some values from: Kit-low proerythroblast
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000002981
IAO_0000115: A basophilic erythroblast that is Lyg 76-high and is Kit-negative.

Kit-negative, Ly-76 high polychromatophilic erythroblast
type: Class
equivalent class: Class
  intersection of: polychromatophilic erythroblast
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001869
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002065
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002979
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000002981
subclass of: polychromatophilic erythroblast
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001869
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002065
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002979
subclass of: Restriction
  on property: RO_0002202
  some values from: Kit-negative, Ly-76 high basophilic erythroblast
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000002981
IAO_0000115: A polychromatophilic erythroblast that is Lyg 76-high and is Kit-negative.
has broad synonym: late basophilic and polychromatophilic erythroblast

CD71-low, GlyA-positive polychromatic erythroblast
type: Class
equivalent class: Class
  intersection of: polychromatophilic erythroblast
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001460
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001945
subclass of: polychromatophilic erythroblast
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001460
subclass of: Restriction
  on property: RO_0002202
  some values from: GlyA-positive basophilic erythroblast
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001945
IAO_0000115: A polychromatiic erythroblast that is Gly-A-positive and CD71-low.

Kit-negative, Ly-76 high orthochromatophilic erythroblasts
type: Class
equivalent class: Class
  intersection of: orthochromatic erythroblast
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001869
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002065
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002979
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000002981
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001945
subclass of: orthochromatic erythroblast
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001869
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002065
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002979
subclass of: Restriction
  on property: RO_0002202
  some values from: Kit-negative, Ly-76 high polychromatophilic erythroblast
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000002981
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001945
IAO_0000115: An orthochromatophilic erythroblast that is ter119-high, CD71-low, and Kit-negative.

CD71-negative, GlyA-positive orthochromatic erythroblast
type: Class
equivalent class: Class
  intersection of: orthochromatic erythroblast
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001945
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001460
subclass of: orthochromatic erythroblast
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001945
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001460
subclass of: Restriction
  on property: RO_0002202
  some values from: CD71-low, GlyA-positive polychromatic erythroblast
IAO_0000115: An erythroblast that is GlyA-positive and CD71-negative.

Ly-76 high reticulocyte
type: Class
equivalent class: Class
  intersection of: enucleated reticulocyte
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000002981
subclass of: enucleated reticulocyte
subclass of: Restriction
  on property: RO_0002202
  some values from: Kit-negative, Ly-76 high orthochromatophilic erythroblasts
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000002981
IAO_0000115: A reticulocyte that is Ly76-high and is Kit-negative.

GlyA-positive reticulocytes
type: Class
equivalent class: Class
  intersection of: enucleated reticulocyte
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001460
subclass of: enucleated reticulocyte
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001460
subclass of: Restriction
  on property: RO_0002202
  some values from: CD71-negative, GlyA-positive orthochromatic erythroblast
IAO_0000115: A reticulocyte that is GlyA-positive.

GlyA-positive erythrocyte
type: Class
equivalent class: Class
  intersection of: enucleate erythrocyte
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001460
subclass of: enucleate erythrocyte
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001460
subclass of: Restriction
  on property: RO_0002202
  some values from: GlyA-positive reticulocytes
IAO_0000115: An enucleate erythrocyte that is GlyA-positive.

Ly-76 high positive erythrocyte
type: Class
equivalent class: Class
  intersection of: enucleate erythrocyte
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000002981
subclass of: enucleate erythrocyte
subclass of: Restriction
  on property: RO_0002202
  some values from: Ly-76 high reticulocyte
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000002981
IAO_0000115: An enucleate erythrocyte that is Lyg-76-high.

Kit-positive megakaryocyte progenitor cell
type: Class
equivalent class: Class
  intersection of: megakaryocyte progenitor cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001833
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001869
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002979
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002065
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000005178
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001479
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001483
subclass of: megakaryocyte progenitor cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001833
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001869
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002979
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002065
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000005178
subclass of: Restriction
  on property: RO_0002202
  some values from: Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001479
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001483
IAO_0000115: A megakaryocyte progenitor cell that is Kit-positive, CD41-positive, CD9-positive, Sca-1-negative, IL7ralpha-negative, CD150-negative, and Fcgamma receptor II/III-low.

CD9-positive, CD41-positive megakaryocyte cell
type: Class
equivalent class: Class
  intersection of: megakaryocyte
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000005178
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000009127
subclass of: megakaryocyte
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000005178
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000009127
subclass of: Restriction
  on property: RO_0002202
  some values from: Kit-positive megakaryocyte progenitor cell
IAO_0000115: A megakaryocyte cell with is CD9-positive and CD41-positive.

basophil mast progenitor cell
type: Class
equivalent class: Class
  intersection of: myeloid lineage restricted progenitor cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000005307
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000007857
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000007858
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000007431
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000016401
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001867
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030221
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0060374
subclass of: myeloid cell
subclass of: granulocytopoietic cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000005307
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000007857
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000007858
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000007431
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000016401
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001867
subclass of: Restriction
  on property: RO_0002202
  some values from: granulocyte monocyte progenitor cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030221
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0060374
IAO_0000115: A cell type that can give rise to basophil and mast cells. This cell is CD34-positive, CD117-positive, CD125-positive, FceRIa-negative, and T1/ST2-negative, and expresses Gata-1, Gata-2, C/EBPa
has exact synonym: BMCP

Fc-epsilon RIalpha-low mast cell progenitor
type: Class
equivalent class: Class
  intersection of: mast cell progenitor
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002979
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001006
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002065
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000009143
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000007431
subclass of: mast cell progenitor
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001006
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002065
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000009143
subclass of: Restriction
  on property: RO_0002202
  some values from: Kit-positive, integrin beta7-high basophil mast progenitor cell
IAO_0000115: A lineage-negative, Kit-positive, CD45-positive mast cell progenitor that is Fc-epsilon RIalpha-low.

Fc-epsilon RIalpha-high basophil progenitor cell
type: Class
equivalent class: Class
  intersection of: basophil progenitor cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002065
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002979
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001003
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000007431
subclass of: basophil progenitor cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002979
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001003
subclass of: Restriction
  on property: RO_0002202
  some values from: Kit-positive, integrin beta7-high basophil mast progenitor cell
IAO_0000115: A lineage negative, Sca1-negative basophil progenitor cell that is Fc epsilon RIalpha-high.

hematopoietic lineage restricted progenitor cell
type: Class
equivalent class: Class
  intersection of: hematopoietic cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001400
subclass of: BFO_0000002
subclass of: CL_0008001
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0001400
subclass of: Restriction
  on property: RO_0002202
  some values from: hematopoietic oligopotent progenitor cell
disjoint with: hematopoietic oligopotent progenitor cell
IAO_0000115: A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells.

hematopoietic oligopotent progenitor cell
type: Class
equivalent class: Class
  intersection of: hematopoietic cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001401
subclass of: BFO_0000002
subclass of: CL_0008001
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0001401
subclass of: Restriction
  on property: RO_0002202
  some values from: hematopoietic multipotent progenitor cell
IAO_0000115: A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities.

short term hematopoietic stem cell
type: Class
equivalent class: Class
  intersection of: Kit and Sca1-positive hematopoietic stem cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002001
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001003
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001833
subclass of: Kit and Sca1-positive hematopoietic stem cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002001
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001003
subclass of: Restriction
  on property: RO_0002202
  some values from: long term hematopoietic stem cell
IAO_0000115: A hematopoietic stem cell capable of rapid replenishment of myeloerythroid progenitors and limited self renewal capability. This cell is Kit-positive, Sca1-positive, CD34-positive, CD150-positive, and is Flt3-negative.
has exact synonym: ST stem cell
has exact synonym: ST-HSC

long term hematopoietic stem cell
type: Class
equivalent class: Class
  intersection of: Kit and Sca1-positive hematopoietic stem cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001003
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002001
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001833
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001843
subclass of: Kit and Sca1-positive hematopoietic stem cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001003
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002001
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001843
IAO_0000115: A hematopoietic stem cell with long term self renewal capability. This cell is Kit-positive, Sca1-positive, CD150-positive, CD90-low, CD34-negative and Flt3-negative.
has exact synonym: LT stem cell
has exact synonym: LT-HSC

Slamf1-negative multipotent progenitor cell
type: Class
equivalent class: Class
  intersection of: hematopoietic multipotent progenitor cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001833
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002001
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002065
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002979
subclass of: hematopoietic multipotent progenitor cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001833
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002001
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002065
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002979
subclass of: Restriction
  on property: RO_0002202
  some values from: Slamf1-positive multipotent progenitor cell
IAO_0000115: A hematopoietic progenitor that has restricted self-renewal capability. Cell is Kit-positive, Ly6-positive, CD150-negative and Flt3-negative.

Slamf1-positive multipotent progenitor cell
type: Class
equivalent class: Class
  intersection of: hematopoietic multipotent progenitor cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001833
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002065
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002979
subclass of: hematopoietic multipotent progenitor cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001833
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002065
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002979
subclass of: Restriction
  on property: RO_0002202
  some values from: short term hematopoietic stem cell
disjoint with: CD34-positive, CD38-negative multipotent progenitor cell
IAO_0000115: A hematopoietic progenitor that has some limited self-renewal capability. Cells are lin-negative, Kit-positive, CD34-positive, and Slamf1-positive.
has exact synonym: KSL cell

CD2-positive, CD5-positive, CD44-positive alpha-beta intraepithelial T cell
type: Class
equivalent class: Class
  intersection of: CD4-positive, alpha-beta intraepithelial T cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001083
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001307
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001839
subclass of: CD4-positive, alpha-beta intraepithelial T cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001083
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001307
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001839
IAO_0000115: Intraepithelial T cells with a memory phenotype of CD2-positive, CD5-positive, and CD44-positive.
has exact synonym: memory alpha beta IEL

T follicular helper cell
type: Class
equivalent class: Class
  intersection of: CD4-positive helper T cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000003450
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001203
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001209
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001860
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001919
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0045830
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0051024
subclass of: CD4-positive helper T cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000003450
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001203
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001209
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001860
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001919
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0045830
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0051024
IAO_0000115: A CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cell located in follicles of secondary lymph nodes that is BCL6-high, ICOS-high and PD1-high, and stimulates follicular B cells to undergo class-switching and antibody production.
has exact synonym: T(FH)
has exact synonym: Tfh
has related synonym: follicular B helper T cell
has related synonym: follicular T cell
has related synonym: follicular T-cell
has related synonym: follicular T-helper cell
has related synonym: follicular helper T cell
has related synonym: follicular helper T-cell

immature NK T cell stage I
type: Class
equivalent class: Class
  intersection of: immature NK T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001307
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001874
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001932
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001004
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000025402
subclass of: immature NK T cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001307
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001874
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001932
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001004
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000025402
IAO_0000115: A CD24-high, CD4-low, CD8-low, CD44-negative, NK1.1-negative NK T cell.

immature NK T cell stage II
type: Class
equivalent class: Class
  intersection of: immature NK T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001307
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001874
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001932
subclass of: immature NK T cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001307
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001874
subclass of: Restriction
  on property: RO_0002202
  some values from: immature NK T cell stage I
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001932
IAO_0000115: A CD24-low, CD44-negative, NK1.1-negative NK T cell.
has exact synonym: NKT.44-NK1.1-.Th

immature NK T cell stage III
type: Class
equivalent class: Class
  intersection of: immature NK T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001874
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001307
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001008
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001932
subclass of: immature NK T cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001874
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001307
subclass of: Restriction
  on property: RO_0002202
  some values from: immature NK T cell stage II
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001008
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001932
IAO_0000115: A CD24-low, CD44-positive, DX5-low, NK1.1-negative NK T cell.
has broad synonym: NKT.44+.NK1.1-.Th

immature NK T cell stage IV
type: Class
equivalent class: Class
  intersection of: immature NK T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001874
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001307
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001008
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001932
subclass of: immature NK T cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001874
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001307
subclass of: Restriction
  on property: RO_0002202
  some values from: immature NK T cell stage III
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001008
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001932
IAO_0000115: A CD24-low, CD44-positive, DX5-high, NK1.1-negative NK T cell.
has broad synonym: NKT.44+.NK1.1-.Th

CD34-positive, CD38-negative multipotent progenitor cell
type: Class
equivalent class: Class
  intersection of: hematopoietic multipotent progenitor cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001015
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001408
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001843
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001003
subclass of: hematopoietic multipotent progenitor cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001015
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001408
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001843
subclass of: Restriction
  on property: RO_0002202
  some values from: CD34-positive, CD38-negative hematopoietic stem cell
IAO_0000115: A hematopoietic multipotent progenitor cell that is CD34-positive, CD38-negative, CD45RA-negative, and CD90-negative.

Kit-positive, integrin beta7-high basophil mast progenitor cell
type: Class
equivalent class: Class
  intersection of: basophil mast progenitor cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002065
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002979
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001479
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001483
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000009143
subclass of: basophil mast progenitor cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002065
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002979
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001479
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001483
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000009143
IAO_0000115: A basophil mast progenitor cell that is Beta-7 integrin-high, Kit-positive FcRgammaII/III-positive and Sca1-negative.

fraction A pre-pro B cell
type: Class
equivalent class: Class
  intersection of: pro-B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002039
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002980
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001015
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001879
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002037
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002065
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001932
subclass of: pro-B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002039
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002980
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001015
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001879
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002037
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002065
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001932
IAO_0000115: A pro-B cell that is CD45R/B220-positive, CD43-positive, HSA-low, BP-1-negative and Ly6c-negative. This cell type is also described as being lin-negative, AA4-positive, Kit-positive, IL7Ra-positive and CD45R-positive.
has broad synonym: fraction A
has related synonym: pre pro B cell

fraction B precursor B cell
type: Class
equivalent class: Class
  intersection of: fraction B/C precursor B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002039
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001014
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001932
subclass of: fraction B/C precursor B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002039
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001014
subclass of: Restriction
  on property: RO_0002202
  some values from: fraction A pre-pro B cell
IAO_0000115: A precursor B cell that is CD45RA-positive, CD43-positive, CD24-positive and BP-1-negative.
has broad synonym: Fr. B
has broad synonym: Fraction B

fraction C precursor B cell
type: Class
equivalent class: Class
  intersection of: fraction B/C precursor B cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000001858
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000001859
  intersection of: Restriction
    on property: has_not_completed
    some values from: GO_0071707
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001014
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001932
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002039
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000003457
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000003460
subclass of: fraction B/C precursor B cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000001858
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000001859
subclass of: Restriction
  on property: has_not_completed
  some values from: GO_0071707
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001014
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002039
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000003457
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000003460
subclass of: Restriction
  on property: RO_0002202
  some values from: fraction B precursor B cell
IAO_0000115: A precursor B cell that is CD45R-positive, CD43-positive, CD24-positive, and BP-positive. Intracellularly expression of surrogate light chain, Rag1 and Rag2, TdT, occurs while there is no expression of mu heavy chain.
has related synonym: Fraction C

fraction C' precursor B cell
type: Class
equivalent class: Class
  intersection of: precursor B cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0035369
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001014
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001380
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001879
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002039
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001932
subclass of: precursor B cell
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0035369
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001014
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001380
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001879
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002039
subclass of: Restriction
  on property: RO_0002202
  some values from: fraction C precursor B cell
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001932
IAO_0000115: A pre-BCR-positive precursor B cell that is CD24-high, CD25-positive, CD43-positive, CD45R-positive and BP-positive.
has broad synonym: Fr. C'
has broad synonym: Fraction C-prime

fraction D precursor B cell
type: Class
equivalent class: Class
  intersection of: precursor B cell
  intersection of: Restriction
    on property: has_not_completed
    some values from: GO_0071708
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0035369
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001002
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001014
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001380
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001932
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002037
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002039
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001879
subclass of: fraction B/C precursor B cell
subclass of: Restriction
  on property: has_not_completed
  some values from: GO_0071708
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0035369
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001014
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001380
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002039
subclass of: Restriction
  on property: RO_0002202
  some values from: fraction C' precursor B cell
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001879
IAO_0000115: A pre-B cell that is pre-BCR-negative, and the kappa- and lambda- light immunoglobulin light chain-negative, CD43-low, and is BP-1-positive, CD45R-positive and CD25-positive. This cell type is also described as being AA4-positive, IgM-negative, CD19-positive, CD43-low/negative, and HSA-positive.
has broad synonym: Fr. D
has exact synonym: fraction D pre-B cell

fraction E immature B cell
type: Class
equivalent class: Class
  intersection of: immature B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001380
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001869
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001002
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001932
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002037
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001879
subclass of: immature B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001380
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001869
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001932
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002037
subclass of: Restriction
  on property: RO_0002202
  some values from: fraction D precursor B cell
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001879
IAO_0000115: An immature B cell that is IgM-positive, CD45R-positive, CD43-low, CD25-negative, and CD127-negative. This cell type has also been described as being AA4-positive, IgM-positive, CD19-positive, CD43-low/negative, and HSA-positive.

fraction F mature B cell
type: Class
equivalent class: Class
  intersection of: mature B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001879
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001880
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002037
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071738
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071753
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001014
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001289
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001338
subclass of: B-2 B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001880
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002037
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0071738
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0071753
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001014
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001338
subclass of: Restriction
  on property: RO_0002202
  some values from: fraction E immature B cell
IAO_0000115: A mature B cell subset originally defined as having being CD45R-positive, IgM-positive, IgD-positive and CD43-negative. Subsequent research demonstrated being CD21-positive and CD23-negative and CD93 negative.

Gr1-low non-classical monocyte
type: Class
equivalent class: Class
  intersection of: non-classical monocyte
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001014
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001012
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001206
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001879
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002062
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001199
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000002980
subclass of: non-classical monocyte
subclass of: Gr1-positive, CD43-positive monocyte
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001014
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001206
subclass of: Restriction
  on property: RO_0002202
  some values from: Gr1-positive, CD43-positive monocyte
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001199
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000002980
IAO_0000115: A resident monocyte that is Gr-1 low, CD43-positive, and CX3CR1-positive.

CD8alpha-positive thymic conventional dendritic cell
type: Class
equivalent class: Class
  intersection of: thymic conventional dendritic cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001084
subclass of: thymic conventional dendritic cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001084
IAO_0000115: A conventional thymic dendritic cell that is CD8alpha-positive.
has exact synonym: CD8alpha-alpha-positive thymic conventional dendritic cell
has exact synonym: DC.8+.Th

pulmonary alveolar type 1 cell
type: Class
equivalent class: Class
  intersection of: pulmonary alveolar epithelial cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0007585
subclass of: pulmonary alveolar epithelial cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0007585
IAO_0000115: A squamous pulmonary alveolar epithelial cell that is flattened and branched. A pulmonary alveolar type 1 cell covers more than 98% of the alveolar surface. This large cell has thin (50-100 nm) cytoplasmic extensions to form the air-blood barrier essential for normal gas exchange.
has exact synonym: lung type 1 cells
has exact synonym: membranous pneumocytes
has exact synonym: pulmonary alveolar type I cell
has exact synonym: small alveolar cells
has exact synonym: squamous alveolar cell
has exact synonym: squamous alveolar lining cell
has exact synonym: type 1 alveolar epithelial cells
has exact synonym: type 1 pneumocyte
has exact synonym: type I alveolar cells
has exact synonym: type I alveolar epithelial cells
has exact synonym: type I pneumocyte
has related synonym: AT1
has related synonym: ATI

pulmonary alveolar type 2 cell
type: Class
equivalent class: Class
  intersection of: pulmonary alveolar epithelial cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032940
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0043129
subclass of: surfactant secreting cell
subclass of: pulmonary alveolar epithelial cell
subclass of: CL_1000272
subclass of: Restriction
  on property: RO_0002202
  some values from: CL_4040003
IAO_0000115: A pulmonary alveolar epithelial cell that modulates the fluid surrounding the alveolar epithelium by secreting and recycling surfactants. This cell type also contributes to tissue repair and can differentiate after injury into a pulmonary alveolar type 1 cell. This cuboidal cell is thicker than squamous alveolar cells, have a rounded apical surface that projects above the level of surrounding epithelium. The free surface is covered by short microvilli.
has exact synonym: cuboidal type II cell
has exact synonym: granular pneumocyte
has exact synonym: great alveolar cell
has exact synonym: lung type 2 cell
has exact synonym: type 2 alveolar epithelial cell
has exact synonym: type 2 alveolocyte
has exact synonym: type 2 pneumocyte
has exact synonym: type II alveolar cell
has exact synonym: type II alveolar epithelial cell
has exact synonym: type II alveolocyte
has exact synonym: type II pneumocyte
has related synonym: AT2
has related synonym: ATII
has related synonym: TII
has related synonym: lung type II cell

type A enteroendocrine cell
type: Class
equivalent class: Class
  intersection of: enteroendocrine cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0070091
subclass of: enteroendocrine cell
subclass of: glucagon secreting cell
IAO_0000115: An enteroendocrine cell that produces glucagon.

Purkinje myocyte
type: Class
subclass of: specialized cardiac myocyte
IAO_0000115: Specialized cardiac myocyte that is subendocardially interspersed with the regular cardiac muscle cell. They are uninucleate cylindrical cells, associated end-to-end in long rows, continue from the node to the atrioventricular bundle; relatively short compared to ordinary myocytes but are nearly twice their diameter.
has exact synonym: Purkinje cell fiber
has exact synonym: Purkinje muscle cell
has exact synonym: myocytus conducens cardiacus

enterocyte of epithelium of large intestine
type: Class
equivalent class: Class
  intersection of: enterocyte
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001278
subclass of: enterocyte
subclass of: epithelial cell of large intestine
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001278
IAO_0000115: Columnar cell which populate the epithelium of large intestine and absorb water. This cell is the most numerous of the epithelial cell types in the large intestine; bear apical microvilli, contain secretory granules in their apical cytoplasm; secretion appears to be largely mucins, but is also rich in antibodies of the IgA type.
has broad synonym: columnar cell
has exact synonym: columnar cell of the colon
has exact synonym: vacuolar absorptive cell

nodal myocyte
type: Class
subclass of: specialized cardiac myocyte
IAO_0000115: A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery.
has broad synonym: pacemaker cell
has exact synonym: P cell
has exact synonym: cardiac pacemaker cell
has exact synonym: myocytus nodalis

endo-epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: RO_0002202
    some values from: endodermal cell
subclass of: BFO_0000002
subclass of: epithelial cell
subclass of: Restriction
  on property: RO_0002202
  some values from: endodermal cell
IAO_0000115: An epithelial cell derived from endoderm.

ecto-epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: RO_0002202
    some values from: ectodermal cell
subclass of: BFO_0000002
subclass of: epithelial cell
subclass of: Restriction
  on property: RO_0002202
  some values from: ectodermal cell
IAO_0000115: An epithelial cell derived from ectoderm.

meso-epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: RO_0002202
    some values from: mesodermal cell
subclass of: BFO_0000002
subclass of: epithelial cell
subclass of: Restriction
  on property: RO_0002202
  some values from: mesodermal cell
IAO_0000115: Epithelial cell derived from mesoderm or mesenchyme.
has exact synonym: epithelial mesenchymal cell

tanycyte
type: Class
subclass of: ependymoglial cell
IAO_0000115: Specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS. Resemble spongioblasts seen in developing brain. Found in the adult brain in the third ventricle, cerebral aqueduct, spinal canal and floor of the fourth ventricle.
has exact synonym: stretch cell

specialized cardiac myocyte
type: Class
subclass of: cardiac muscle cell
IAO_0000115: A cardiac myocyte that is an excitable cells in the myocardium, specifically in the conducting system of heart.

nongranular leukocyte
type: Class
equivalent class: Class
  intersection of: leukocyte
  intersection of: Restriction
    on property: lacks_part
    some values from: GO_0030141
subclass of: leukocyte
subclass of: Restriction
  on property: lacks_part
  some values from: GO_0030141
IAO_0000115: A leukocyte that lacks granules.
has exact synonym: agranular leukocyte

interstitial cell of Cajal
type: Class
equivalent class: Class
  intersection of: neurecto-epithelial cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0043134
subclass of: neurecto-epithelial cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0043134
IAO_0000115: This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise.
has exact synonym: ICC
has exact synonym: intestinal pacemaker cell

bone marrow cell
type: Class
equivalent class: Class
  intersection of: bone cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002371
subclass of: bone cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002371
IAO_0000115: A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells.

cortical cell of adrenal gland
type: Class
equivalent class: Class
  intersection of: meso-epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001235
subclass of: steroid hormone secreting cell
subclass of: meso-epithelial cell
subclass of: CL_1001601
IAO_0000115: A cell of the adrenal cortex. Cell types include those that synthesize and secrete chemical derivatives (steroids) of cholesterol.
has exact synonym: adrenal cortex cell
has exact synonym: adrenocortical cell

regular cardiac myocyte
type: Class
subclass of: cardiac muscle cell
IAO_0000115: A cardiac myocyte that is connected to other cardiac myocytes by transverse intercalated discs (GO:0014704) at a regular interval.
has exact synonym: regular cardiac muscle cell
has exact synonym: regular cardiac muscle fiber

CD38-positive naive B cell
type: Class
equivalent class: Class
  intersection of: naive B cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001408
subclass of: naive B cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001408
IAO_0000115: A CD38-positive naive B cell is a mature B cell that has the phenotype CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery.
has exact synonym: CD38+ naive B cell
has exact synonym: CD38+ naive B lymphocyte
has exact synonym: CD38+ naive B-cell
has exact synonym: CD38+ naive B-lymphocyte
has exact synonym: CD38-positive naive B lymphocyte
has exact synonym: CD38-positive naive B-cell
has exact synonym: CD38-positive naive B-lymphocyte

CD38-negative naive B cell
type: Class
equivalent class: Class
  intersection of: naive B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001408
subclass of: naive B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001408
IAO_0000115: A CD38-negative naive B cell is a mature B cell that has the phenotype CD38-negative, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery.
has exact synonym: CD38- naive B cell
has exact synonym: CD38- naive B lymphocyte
has exact synonym: CD38- naive B-cell
has exact synonym: CD38- naive B-lymphocyte
has exact synonym: CD38-negative naive B lymphocyte
has exact synonym: CD38-negative naive B-cell
has exact synonym: CD38-negative naive B-lymphocyte

IgG-positive double negative memory B cell
type: Class
equivalent class: Class
  intersection of: double negative memory B cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071735
subclass of: double negative memory B cell
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0071735
IAO_0000115: An IgG-positive double negative memory B cell is a double negative memory B cell with the phenotype IgG-positive, IgD-negative, and CD27-negative.
has exact synonym: IgG+ dn memory B cell
has exact synonym: IgG+ dn memory B lymphocyte
has exact synonym: IgG+ dn memory B-cell
has exact synonym: IgG+ dn memory B-lymphocyte
has exact synonym: IgG+ double negative memory B cell
has exact synonym: IgG+ double negative memory B lymphocyte
has exact synonym: IgG+ double negative memory B-cell
has exact synonym: IgG+ double negative memory B-lymphocyte
has exact synonym: IgG-positive dn memory B cell
has exact synonym: IgG-positive dn memory B lymphocyte
has exact synonym: IgG-positive dn memory B-cell
has exact synonym: IgG-positive dn memory B-lymphocyte
has exact synonym: IgG-positive double negative memory B lymphocyte
has exact synonym: IgG-positive double negative memory B-cell
has exact synonym: IgG-positive double negative memory B-lymphocyte

IgG-negative double negative memory B cell
type: Class
equivalent class: Class
  intersection of: double negative memory B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0071735
subclass of: double negative memory B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0071735
IAO_0000115: An IgG-negative double negative memory B cell is a double negative memory B cell with the phenotype IgG-negative, IgD-negative, and CD27-negative.
has exact synonym: IgG- dn memory B cell
has exact synonym: IgG- dn memory B lymphocyte
has exact synonym: IgG- dn memory B-cell
has exact synonym: IgG- dn memory B-lymphocyte
has exact synonym: IgG- double negative memory B cell
has exact synonym: IgG- double negative memory B lymphocyte
has exact synonym: IgG- double negative memory B-cell
has exact synonym: IgG- double negative memory B-lymphocyte
has exact synonym: IgG-negative dn memory B cell
has exact synonym: IgG-negative dn memory B lymphocyte
has exact synonym: IgG-negative dn memory B-cell
has exact synonym: IgG-negative dn memory B-lymphocyte
has exact synonym: IgG-negative double negative memory B lymphocyte
has exact synonym: IgG-negative double negative memory B-cell
has exact synonym: IgG-negative double negative memory B-lymphocyte

CD38-positive IgG memory B cell
type: Class
equivalent class: Class
  intersection of: IgG memory B cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001408
subclass of: IgG memory B cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001408
IAO_0000115: A CD38-positive IgG memory B cell is a class switched memory B cell that expresses IgG on the cell surface with the phenotype CD38-positive and IgG-positive.
has exact synonym: CD38+ IgG memory B cell
has exact synonym: CD38+ IgG memory B lymphocyte
has exact synonym: CD38+ IgG memory B-cell
has exact synonym: CD38+ IgG memory B-lymphocyte
has exact synonym: CD38-positive IgG memory B lymphocyte
has exact synonym: CD38-positive IgG memory B-cell
has exact synonym: CD38-positive IgG memory B-lymphocyte

IgD-positive CD38-positive IgG memory B cell
type: Class
equivalent class: Class
  intersection of: CD38-positive IgG memory B cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071738
subclass of: CD38-positive IgG memory B cell
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0071738
IAO_0000115: An IgD-positive CD38-positive IgG memory B cell is a CD38-positive IgG-positive class switched memory B cell that has class switched and expresses IgD on the cell surface with the phenotype IgD-positive, CD38-positive, and IgG-positive.

IgD-negative CD38-positive IgG memory B cell
type: Class
equivalent class: Class
  intersection of: CD38-positive IgG memory B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0071738
subclass of: IgD-negative memory B cell
subclass of: CD38-positive IgG memory B cell
IAO_0000115: An IgD-negative CD38-positive IgG memory B cell is a CD38-positive IgG-positive that has class switched and lacks expression of IgD on the cell surface with the phenotype IgD-negative, CD38-positive, and IgG-positive.

CD38-negative IgG memory B cell
type: Class
equivalent class: Class
  intersection of: IgG memory B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0071738
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001408
subclass of: IgG memory B cell
subclass of: IgD-negative memory B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001408
IAO_0000115: A CD38-negative IgG memory B cell is a IgG-positive class switched memory B cell that has class switched and expresses IgG on the cell surface with the phenotype CD38-negative, IgD-negative, and IgG-positive.

B220-positive CD38-positive naive B cell
type: Class
equivalent class: Class
  intersection of: CD38-positive naive B cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001014
subclass of: CD38-positive naive B cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001014
IAO_0000115: A B220-positive CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-positive, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery.
has exact synonym: B220+CD38+ naive B cell
has exact synonym: B220+CD38+ naive B lymphocyte
has exact synonym: B220+CD38+ naive B-cell
has exact synonym: B220+CD38+ naive B-lymphocyte
has exact synonym: B220-positive CD38-positive naive B lymphocyte
has exact synonym: B220-positive CD38-positive naive B-cell
has exact synonym: B220-positive CD38-positive naive B-lymphocyte
has exact synonym: CD38+B220+ naive B cell
has exact synonym: CD38+B220+ naive B lymphocyte
has exact synonym: CD38+B220+ naive B-cell
has exact synonym: CD38+B220+ naive B-lymphocyte

B220-low CD38-positive naive B cell
type: Class
equivalent class: Class
  intersection of: CD38-positive naive B cell
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001014
subclass of: B220-positive CD38-positive naive B cell
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001014
IAO_0000115: A B220-low CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-low, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery.

CD38-negative unswitched memory B cell
type: Class
equivalent class: Class
  intersection of: unswitched memory B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001408
subclass of: unswitched memory B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001408
IAO_0000115: An CD38-negative unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-negative, IgD-positive, CD138-negative, and IgG-negative.
has exact synonym: CD38- unswitched memory B cell
has exact synonym: CD38- unswitched memory B lymphocyte
has exact synonym: CD38- unswitched memory B-cell
has exact synonym: CD38- unswitched memory B-lymphocyte
has exact synonym: CD38-negative unswitched memory B lymphocyte
has exact synonym: CD38-negative unswitched memory B-cell
has exact synonym: CD38-negative unswitched memory B-lymphocyte

B220-positive CD38-negative unswitched memory B cell
type: Class
equivalent class: Class
  intersection of: CD38-negative unswitched memory B cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001014
subclass of: CD38-negative unswitched memory B cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001014
IAO_0000115: A B220-positive CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-positive, CD38-negative, IgD-positive, CD138-negative, and IgG-negative.

B220-low CD38-negative unswitched memory B cell
type: Class
equivalent class: Class
  intersection of: CD38-negative unswitched memory B cell
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001014
subclass of: B220-positive CD38-negative unswitched memory B cell
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001014
IAO_0000115: A B220-low CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-low, CD38-negative, IgD-positive, CD138-negative, and IgG-negative.

CD38-positive unswitched memory B cell
type: Class
equivalent class: Class
  intersection of: unswitched memory B cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001408
subclass of: unswitched memory B cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001408
IAO_0000115: A CD38-positive unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-positive, IgD-positive, CD138-negative, and IgG-negative.
has exact synonym: CD38+ unswitched memory B cell
has exact synonym: CD38+ unswitched memory B lymphocyte
has exact synonym: CD38+ unswitched memory B-cell
has exact synonym: CD38+ unswitched memory B-lymphocyte
has exact synonym: CD38-positive unswitched memory B lymphocyte
has exact synonym: CD38-positive unswitched memory B-cell
has exact synonym: CD38-positive unswitched memory B-lymphocyte

B220-positive CD38-positive unswitched memory B cell
type: Class
equivalent class: Class
  intersection of: CD38-positive unswitched memory B cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001014
subclass of: CD38-positive unswitched memory B cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001014
IAO_0000115: A B220-positive CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-positive, CD38-positive, IgD-positive, CD138-negative, and IgG-negative.

B220-low CD38-positive unswitched memory B cell
type: Class
equivalent class: Class
  intersection of: CD38-positive unswitched memory B cell
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001014
subclass of: B220-positive CD38-positive unswitched memory B cell
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001014
IAO_0000115: A B220-low CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-low, CD38-positive, IgD-positive, CD138-negative, and IgG-negative.

IgG-negative class switched memory B cell
type: Class
equivalent class: Class
  intersection of: class switched memory B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0071735
subclass of: class switched memory B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0071735
IAO_0000115: A class switched memory B cell that lacks IgG on the cell surface.
has exact synonym: IgG- class switched memory B cell
has exact synonym: IgG- class switched memory B lymphocyte
has exact synonym: IgG- class switched memory B-cell
has exact synonym: IgG- class switched memory B-lymphocyte
has exact synonym: IgG-negative class switched memory B lymphocyte
has exact synonym: IgG-negative class switched memory B-cell
has exact synonym: IgG-negative class switched memory B-lymphocyte

CD38-negative IgG-negative class switched memory B cell
type: Class
equivalent class: Class
  intersection of: IgG-negative class switched memory B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001408
subclass of: IgG-negative class switched memory B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001408
IAO_0000115: A CD38-negative IgG-negative memory B cell is a IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-negative and IgG-negative.

CD38-positive IgG-negative class switched memory B cell
type: Class
equivalent class: Class
  intersection of: IgG-negative class switched memory B cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001408
subclass of: IgG-negative class switched memory B cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001408
IAO_0000115: A CD38-positive IgG-negative memory B cell is an IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-positive and IgG-negative.

CD24-positive CD38-negative IgG-negative class switched memory B cell
type: Class
equivalent class: Class
  intersection of: CD38-negative IgG-negative class switched memory B cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001932
subclass of: CD38-negative IgG-negative class switched memory B cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001932
IAO_0000115: An CD24-positive CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-positive, CD38-negative, and IgG-negative.

CD24-negative CD38-negative IgG-negative class switched memory B cell
type: Class
equivalent class: Class
  intersection of: CD38-negative IgG-negative class switched memory B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001932
subclass of: CD38-negative IgG-negative class switched memory B cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001932
IAO_0000115: A CD24-negative CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-negative, CD38-negative, and IgG-negative.

B220-positive CD38-positive IgG-negative class switched memory B cell
type: Class
equivalent class: Class
  intersection of: CD38-positive IgG-negative class switched memory B cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001014
subclass of: CD38-positive IgG-negative class switched memory B cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001014
IAO_0000115: A B220-positive CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-positive, CD38-positive, and IgG-negative.

B220-low CD38-positive IgG-negative class switched memory B cell
type: Class
equivalent class: Class
  intersection of: CD38-positive IgG-negative class switched memory B cell
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001014
subclass of: B220-positive CD38-positive IgG-negative class switched memory B cell
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001014
IAO_0000115: A B220-low CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-low, CD38-positive, and IgG-positive.

CD27-positive gamma-delta T cell
type: Class
equivalent class: Class
  intersection of: mature gamma-delta T cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001963
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032609
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0030217
subclass of: mature gamma-delta T cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001963
subclass of: Restriction
  on property: RO_0002202
  some values from: CD25-positive, CD27-positive immature gamma-delta T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032609
subclass of: Restriction
  on property: RO_0002353
  some values from: GO_0030217
IAO_0000115: A circulating gamma-delta T cell that is CD27-positive and capable of producing IFN-gamma.
has exact synonym: gammadelta27-positive
has exact synonym: gd27-positive

CD27-negative gamma-delta T cell
type: Class
equivalent class: Class
  intersection of: mature gamma-delta T cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000003455
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001963
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032620
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0030217
subclass of: mature gamma-delta T cell
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000003455
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001963
subclass of: Restriction
  on property: RO_0002202
  some values from: CD25-positive, CD27-positive immature gamma-delta T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032620
subclass of: Restriction
  on property: RO_0002353
  some values from: GO_0030217
IAO_0000115: A circulating gamma-delta T cell that expresses RORgamma(t), is CD27-negative and is capable of IL-17 secretion.
has exact synonym: gammadelta-17 cells

CD25-positive, CD27-positive immature gamma-delta T cell
type: Class
equivalent class: Class
  intersection of: immature gamma-delta T cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002370
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001380
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001919
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001307
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001318
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001932
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001083
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001839
subclass of: immature gamma-delta T cell
subclass of: thymocyte
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001380
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001919
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001307
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001318
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001932
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001083
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001839
IAO_0000115: A CD25-positive, CD27-positive immature gamma-delta T cell found in the thymus that has an immature phenotype (i.e. CD24-high, CD25-high, CD62L-high, CD44-high, CD2-low, CD5-low).

innate effector T cell
type: Class
equivalent class: Class
  intersection of: effector T cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0045087
subclass of: effector T cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0045087
IAO_0000115: A T cell with a receptor of limited diversity that is capable of immediate effector functions upon stimulation.

regular atrial cardiac myocyte
type: Class
subclass of: regular cardiac myocyte
IAO_0000115: Regular cardiac myocyte of a cardiac atrium.
has exact synonym: atrial cardiac muscle cell
has exact synonym: atrial myocyte
has exact synonym: regular atrial cardiac muscle fiber
has exact synonym: regular cardiac muscle cell of atrium

regular ventricular cardiac myocyte
type: Class
subclass of: regular cardiac myocyte
IAO_0000115: Regular cardiac myocyte of a cardiac ventricle.
has broad synonym: ventricular cardiac muscle cell
has exact synonym: regular cardiac muscle cell of ventricle
has exact synonym: regular ventricular cardiac muscle fiber
has exact synonym: ventricular myocyte

stromal cell of ovary
type: Class
equivalent class: Class
  intersection of: stromal cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000992
subclass of: stromal cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000992
IAO_0000115: A stomal cell of the ovary
has exact synonym: ovarian stromal cell

endothelial cell of lymphatic vessel
type: Class
equivalent class: Class
  intersection of: endothelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001473
subclass of: endothelial cell of vascular tree
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001473
subclass of: Restriction
  on property: RO_0002202
  some values from: CL_0005022
IAO_0000115: A endothelial cell of a lymphatic vessel. The border of the oak leaf-shaped endothelial cell of initial lymphatics are joined by specialized buttons. The discontinuous feature of buttons distinguishes them from zippers in collecting lymphatics, but both types of junctions are composed of proteins typical of adherens junctions and tight junctions found in the endothelium of blood vessels. Buttons seal the sides of flaps of the oak leaf-shaped endothelial cell, leaving open the tips of flaps as routes for fluid entry without disassembly and reformation of intercellular junctions.
has exact synonym: LEC
has exact synonym: lymphatic endothelial cell

endothelial cell of vascular tree
type: Class
subclass of: endothelial cell
IAO_0000115: An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels.
has exact synonym: vascular endothelial cell
has narrow synonym: cubodial endothelial cell of vascular tree

acinar cell of sebaceous gland
type: Class
equivalent class: Class
  intersection of: sebum secreting cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0003487
subclass of: sebum secreting cell
subclass of: acinar cell
subclass of: CL_1000448
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0003487
IAO_0000115: A sebum secreting cell of the skin that secretes sebum into the hair follicles.
has broad synonym: sebocyte

ciliated columnar cell of tracheobronchial tree
type: Class
subclass of: epithelial cell of tracheobronchial tree
subclass of: CL_0005012
subclass of: CL_4030034
subclass of: Restriction
  on property: RO_0002202
  some values from: intermediate epitheliocyte
IAO_0000115: A ciliated columnar cell found in the trachea and bronchus. Vary from low to tall columnar; possesses up to 300 cilia at its surface, interspersed with long irregular microvilli with the cilia varying in length from about 6um in the trachea to about 4um in the terminal bronchioles; driving force of the ciliary current in the bronchial tree.

dental pulp cell
type: Class
equivalent class: Class
  intersection of: general ecto-epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001754
subclass of: general ecto-epithelial cell
subclass of: connective tissue cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001754
IAO_0000115: A cell found within the dental pulp.

epithelial cell of uterus
type: Class
equivalent class: Class
  intersection of: endo-epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000995
subclass of: endo-epithelial cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000995
IAO_0000115: An epithelial cell of the uterus.

corneocyte
type: Class
subclass of: BFO_0000002
subclass of: anucleate cell
subclass of: keratin accumulating cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002027
subclass of: Restriction
  on property: RO_0002202
  some values from: keratinocyte
IAO_0000115: The dead keratin-filled squamous cell of the stratum corneum. This cell type lacks a nucleus.

general ecto-epithelial cell
type: Class
subclass of: ecto-epithelial cell
IAO_0000115: Epithelial cells derived from general body ectoderm and ectoderm placodes.

olfactory epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0050911
subclass of: sensory epithelial cell
subclass of: chemoreceptor cell
subclass of: neurecto-epithelial cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0050911
IAO_0000115: A specialized cell involved in sensory perception of smell.

follicular cell of ovary
type: Class
subclass of: follicular epithelial cell
subclass of: meso-epithelial cell
IAO_0000115: A cell within the follicle of an ovary.

epithelial cell of stomach
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000945
subclass of: epithelial cell of alimentary canal
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000945
IAO_0000115: An epithelial cell found in the lining of the stomach.

mucous cell of stomach
type: Class
equivalent class: Class
  intersection of: epithelial cell of stomach
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001199
subclass of: CL_0002659
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001199
IAO_0000115: A mucous cell in the epithelium of the stomach.

basal cell of epidermis
type: Class
equivalent class: Class
  intersection of: basal cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001003
subclass of: keratinocyte
subclass of: basal cell
subclass of: CL_0011026
subclass of: CL_1000428
IAO_0000115: A basally situated, mitotically active, columnar-shaped keratinocyte attached to the basement membrane.

glomerular endothelial cell
type: Class
equivalent class: Class
  intersection of: endothelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000074
subclass of: fenestrated endothelial cell
subclass of: CL_0002681
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000074
IAO_0000115: An endothelial cell found in the glomerulus of the kidney. This cell is flattened, highly fenestrated, and plays a vital role in the formation of glomerular ultrafiltrate.

granulocytopoietic cell
type: Class
equivalent class: Class
  intersection of: myeloid lineage restricted progenitor cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030851
subclass of: myeloid lineage restricted progenitor cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030851
IAO_0000115: A cell involved in the formation of a granulocyte.

metamyelocyte
type: Class
subclass of: myeloid cell
subclass of: granulocytopoietic cell
subclass of: Restriction
  on property: RO_0002202
  some values from: myelocyte
IAO_0000115: A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a myelocyte and a band form cell. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare.

myelocyte
type: Class
subclass of: myeloid cell
subclass of: granulocytopoietic cell
subclass of: Restriction
  on property: RO_0002202
  some values from: promyelocyte
IAO_0000115: A cell type that is the first of the maturation stages of the granulocytic leukocytes normally found in the bone marrow. Granules are seen in the cytoplasm. The nuclear material of the myelocyte is denser than that of the myeloblast but lacks a definable membrane. The cell is flat and contains increasing numbers of granules as maturation progresses.

monopoietic cell
type: Class
equivalent class: Class
  intersection of: myeloid lineage restricted progenitor cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0030224
subclass of: myeloid lineage restricted progenitor cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030224
IAO_0000115: A cell involved in the formation of a monocyte (monopoiesis).

hepatic stem cell
type: Class
equivalent class: Class
  intersection of: multi fate stem cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002107
subclass of: multi fate stem cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002107
IAO_0000115: A stem cell that can give rise to the cells of the liver. The term usually refers to the self-renewing pool of hepatocyte precursors in the adult liver (differently from 'hepatoblast', often used for fetal precursors of hepatocytes).
has related synonym: HpSC

epithelial cell of tracheobronchial tree
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0008397
subclass of: CL_0002632
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0008397
IAO_0000115: An epithelial cell of the tracheobronchial tree.

intermediate epitheliocyte
type: Class
subclass of: epithelial cell of tracheobronchial tree
IAO_0000115: An epithelial cell present in the trachea and bronchi; columnar in shape; generally lack cilia; immature forms of ciliated or secretory cells which have been formed from stem cells.
has exact synonym: undifferentiated columnar cell of tracheobronchial tree

immature dendritic epithelial T cell precursor
type: Class
subclass of: fetal thymocyte
IAO_0000115: A double negative thymocyte that has a T cell receptor consisting of a gamma chain that has as part a Vgamma3 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-positive. This cell-type is found in the fetal thymus with highest numbers occurring at E17-E18.
has exact synonym: immature DEC precursor
has exact synonym: immature DETC precursor

vertebrate lens cell
type: Class
subclass of: epithelial cell
subclass of: crystallin accumulating cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000965
IAO_0000115: A cell comprising the transparent, biconvex body separating the posterior chamber and vitreous body, and constituting part of the refracting mechanism of the mammalian eye.

epithelial cell of prostate
type: Class
equivalent class: Class
  intersection of: endo-epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002367
subclass of: endo-epithelial cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002367
IAO_0000115: An epithelial cell of the prostate.
has exact synonym: prostate epithelial cell

epithelial cell of prostatic acinus
type: Class
equivalent class: Class
  intersection of: epithelial cell of prostate
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0004179
subclass of: epithelial cell of prostate
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0004179
IAO_0000115: An epithelial cell of the prostatic acinus.
has exact synonym: acinar epithelial cell of prostate

basal cell of prostatic acinus
type: Class
equivalent class: Class
  intersection of: basal cell of prostate epithelium
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0004179
subclass of: epithelial cell of prostatic acinus
subclass of: basal cell of prostate epithelium
IAO_0000115: A cell of the basal layer of the epithelium in the prostatic acinus.
has exact synonym: basal epithelial cell of prostatic acinus

marrow fibroblast
type: Class
equivalent class: Class
  intersection of: fibroblast
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002371
subclass of: fibroblast
subclass of: bone marrow cell
IAO_0000115: A fibroblast in the bone marrow.

pulmonary interstitial fibroblast
type: Class
equivalent class: Class
  intersection of: fibroblast
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001004
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0005169
subclass of: fibroblast
subclass of: CL_4030031
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001004
IAO_0000115: A fibroblasts found in interstitial spaces in the pulmonary tract. Greater numbers of these cells are found in idiopathic pulmonary fibrosis.
has exact synonym: pulmonary myofibroblast
has exact synonym: pulmonary septal cell

nucleate cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0002505
subclass of: cell
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0002505
IAO_0000115: A cell containing at least one nucleus.

epithelial cell of alimentary canal
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001555
subclass of: endo-epithelial cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001555
IAO_0000115: An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus.

epithelial cell of esophagus
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001043
subclass of: epithelial cell of alimentary canal
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001043
IAO_0000115: An epithelial cell of the esophagus.

epithelial cell of large intestine
type: Class
equivalent class: Class
  intersection of: CL_0002563
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000059
subclass of: CL_0002563
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000059
IAO_0000115: An epithelial cell of the large intestine.
has related synonym: epithelial cell of colon

epithelial cell of small intestine
type: Class
equivalent class: Class
  intersection of: CL_0002563
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002108
subclass of: CL_0002563
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002108
IAO_0000115: An epithelial cell of the small intestine.

epithelial cell of thyroid gland
type: Class
equivalent class: Class
  intersection of: endo-epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002046
subclass of: glandular epithelial cell
subclass of: endo-epithelial cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002046
IAO_0000115: An epithelial cell of thyroid gland.

epithelial cell of parathyroid gland
type: Class
equivalent class: Class
  intersection of: endo-epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001132
subclass of: endo-epithelial cell
subclass of: CL_1001593
IAO_0000115: An epithelial cell of the parathyroid gland.

type A cell of stomach
type: Class
equivalent class: Class
  intersection of: type A enteroendocrine cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000945
subclass of: type A enteroendocrine cell
subclass of: CL_0002659
IAO_0000115: A type of enteroendocrine cell found in the stomach that secretes glucagon.

type D cell of colon
type: Class
equivalent class: Class
  intersection of: type D enteroendocrine cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001155
subclass of: type D enteroendocrine cell
subclass of: CL_0009042
IAO_0000115: A D cell located in the colon.
has exact synonym: colon D-cell
has exact synonym: colonic delta cell
has exact synonym: delta cell of colon

type D cell of small intestine
type: Class
equivalent class: Class
  intersection of: type D enteroendocrine cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002108
subclass of: type D enteroendocrine cell
subclass of: CL_0009006
IAO_0000115: A type D cell of the small intestine.
has exact synonym: delta cell of small intestine
has exact synonym: small intestine D-cell
has exact synonym: small intestine delta cell

type D cell of stomach
type: Class
equivalent class: Class
  intersection of: type D enteroendocrine cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000945
subclass of: type D enteroendocrine cell
subclass of: CL_0002659
IAO_0000115: A type D cell found in the stomach.
has exact synonym: delta cell of stomach
has exact synonym: stomach D-cell
has exact synonym: stomach delta cell

histamine secreting cell
type: Class
equivalent class: Class
  intersection of: secretory cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0001821
subclass of: biogenic amine secreting cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0001821
IAO_0000115: A cell type that secretes histamine.

pancreatic PP cell
type: Class
equivalent class: Class
  intersection of: PP cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000006
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001264
subclass of: PP cell
subclass of: CL_0008024
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000006
IAO_0000115: A PP cell located in the islets of the pancreas.
has exact synonym: PP cell of pancreatic islet
has exact synonym: PP-cell of pancreatic islet
has exact synonym: pancreatic polypeptide-secreting cell

epithelial cell of thymus
type: Class
equivalent class: Class
  intersection of: endo-epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002370
subclass of: endo-epithelial cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002370
IAO_0000115: An epithelial cell of the thymus. Epithelial reticular cells are pleomorphic, stellate, non-phagocytic cells which seem to be supportive in function and are held together by desmosomes. They replace the fibroblastoid reticular cells found in other lymphoid organs. Other epithelial cells in the medulla have the ultrastructure of secretory cells. Although different epithelial cells throughout the thymus appear alike by light microscopy their ultrastructure and function varies.
has exact synonym: epithelial cell of thymus gland
has exact synonym: epithelial reticular cell
has exact synonym: epithelial reticular cell of thymus
has exact synonym: thymic epithelial cell

type B synovial cell
type: Class
equivalent class: Class
  intersection of: stromal cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002018
subclass of: synovial cell
subclass of: stromal cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002018
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0030213
subclass of: Restriction
  on property: RO_0003000
  some values from: UBERON_0001090
IAO_0000115: A resident stromal cell located in the synovial membrane and responsible for the production of immune-related cytokines and chemokines. This cell type secretes glycoproteins and hyaluronic acid, has abundant granular endoplasmic reticulum, but contains fewer vacuoles and vesicles.
has exact synonym: fibroblast-like synoviocyte
has exact synonym: synovial fibroblast

epithelial cell of distal tubule
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0004135
subclass of: meso-epithelial cell
subclass of: CL_1000494
subclass of: CL_1000615
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0004135
IAO_0000115: An epithelial cell of the distal convoluted tubule of the kidney that helps regulate systemic levels of potassium, sodium, calcium, and pH.
has exact synonym: kidney distal tubule epithelial cell

epithelial cell of proximal tubule
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0004134
subclass of: meso-epithelial cell
subclass of: CL_1000494
subclass of: CL_1000615
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0004134
IAO_0000115: An epithelial cell of the proximal tubule of the kidney.
has exact synonym: kidney proximal tubule epithelial cell

brush border cell of the proximal tubule
type: Class
equivalent class: Class
  intersection of: epithelial cell of proximal tubule
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0005903
subclass of: brush border epithelial cell
subclass of: epithelial cell of proximal tubule
IAO_0000115: A brush border epithelial cell located in the proximal tubule of the kidney, essential for reabsorbing substances like glucose and amino acids from the glomerular filtrate. These cells also secrete organic ions, playing a crucial role in maintaining kidney homeostasis, including electrolyte and acid-base balance, and excreting metabolic waste.

epithelial cell of skin gland
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002419
subclass of: general ecto-epithelial cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002419
IAO_0000115: An epithelial cell of a skin gland.
has exact synonym: epithelial cell of gland of skin

endocrine-paracrine cell of prostate gland
type: Class
equivalent class: Class
  intersection of: general ecto-epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002367
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0046879
subclass of: glandular epithelial cell
subclass of: general ecto-epithelial cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002367
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0046879
IAO_0000115: An ecto-epithelial cell of the prostate gland that secretes hormones.
has exact synonym: glandular cell of prostate
has exact synonym: neuro-epithelial cell of prostate gland

neural cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001016
subclass of: cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001016
IAO_0000115: A cell that is part of the nervous system.

connective tissue cell
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002384
subclass of: cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002384
IAO_0000115: A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone.

embryonic cell (metazoa)
type: Class
subclass of: cell
IAO_0000115: A cell of the embryo.

embryonic stem cell
type: Class
subclass of: stem cell
subclass of: embryonic cell (metazoa)
IAO_0000115: A stem cell of embryonic origin.
has exact synonym: ESC

amniocyte
type: Class
equivalent class: Class
  intersection of: extraembryonic cell
  intersection of: Restriction
    on property: RO_0001025
    some values from: UBERON_0000173
subclass of: extraembryonic cell
subclass of: Restriction
  on property: RO_0001025
  some values from: UBERON_0000173
IAO_0000115: A cell of a fetus which is suspended in the amniotic fluid. Amniocytes are considered to arise from several tissues including fetal skin, the fetal urinary tract, umbilical cord, and the inner amniotic surface.

lactocyte
type: Class
equivalent class: Class
  intersection of: glandular epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0003214
subclass of: milk secreting cell
subclass of: general ecto-epithelial cell
subclass of: CL_1001586
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0003214
subclass of: Restriction
  on property: RO_0002202
  some values from: CL_4033057
IAO_0000115: A milk-producing glandular epithelial cell that is part of a mammary gland alveolus and differentiates from a luminal adaptive secretory precursor cell during secretory differentiation (also termed lactogenesis I). Following secretory activation (also termed lactogenesis II), a lactocyte is involved in the synthesis and/or transport of milk constituents including proteins, oligosaccharides, lactose, micronutrients, fat, hormones, immunoglobulins, and cytokines into the lumen of the lactating mammary gland.
has broad synonym: mammary alveolar cell
has exact synonym: epithelial cell of lactiferous gland
has exact synonym: lactaction-associated mammary epithelial cell
has exact synonym: lactation-derived mammary cell
has exact synonym: luminal cell of alveolus of lactiferous gland
has exact synonym: mammary alveolar epithelial cell
has exact synonym: mammary gland alveolar epithelial cell
has related synonym: LMC

luminal epithelial cell of mammary gland
type: Class
subclass of: BFO_0000002
subclass of: branched duct epithelial cell
subclass of: mammary gland epithelial cell
subclass of: Restriction
  on property: RO_0002202
  some values from: CL_0009116
IAO_0000115: A mammary epithelial cell that occurs in the lumen of the ductal and alveoli structure in the breast.
has broad synonym: mature luminal cell

mammary gland epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001911
subclass of: epithelial cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001911
IAO_0000115: An epithelial cell of the mammary gland.
has exact synonym: breast epithelial cell
has exact synonym: mammary epithelial cell

bronchial epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002185
subclass of: epithelial cell of tracheobronchial tree
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002031
IAO_0000115: An epithelial cell of the bronchus.

basal epithelial cell of tracheobronchial tree
type: Class
subclass of: epithelial cell of tracheobronchial tree
IAO_0000115: An epithelial cell type that lacks the columnar shape typical for other respiratory epithelial cells. This cell type is able to differentiate into other respiratory epithelial cells in response to injury.

ciliated cell of the bronchus
type: Class
equivalent class: Class
  intersection of: ciliated cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002185
subclass of: ciliated columnar cell of tracheobronchial tree
subclass of: bronchial epithelial cell
IAO_0000115: A ciliated cell of the bronchus.

neural crest derived adipocyte
type: Class
equivalent class: Class
  intersection of: adipocyte
  intersection of: Restriction
    on property: RO_0002202
    some values from: migratory neural crest cell
subclass of: adipocyte
subclass of: Restriction
  on property: RO_0002202
  some values from: neural crest derived fibroblast
IAO_0000115: An adipocyte derived from a neural crest cell.

preadipocyte
type: Class
subclass of: fibroblast
IAO_0000115: An undifferentiated fibroblast that can be stimulated to form a fat cell.

brown preadipocyte
type: Class
subclass of: preadipocyte
IAO_0000115: A preadipocyte that is capable of differentiating into a brown adipocyte. This cell type expresses uncoupling protein-1, PPAR-gamma, PR-domain-containing 16; and PGC-1alpha (peroxisome proliferator-activated receptor-gamma (PPARgamma) coactivator-1alpha).

CD56-positive, CD161-positive immature natural killer cell, human
type: Class
equivalent class: Class
  intersection of: immature natural killer cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001003
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001024
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001381
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001874
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002065
  intersection of: Restriction
    on property: RO_0002162
    some values from: NCBITaxon 9606
subclass of: immature natural killer cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001003
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001024
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001381
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001874
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002065
subclass of: Restriction
  on property: RO_0002162
  some values from: NCBITaxon 9606
subclass of: Restriction
  on property: RO_0002202
  some values from: CD56-negative, CD161-positive immature natural killer cell, human
IAO_0000115: A natural killer cell that is developmentally immature, has the phenotype CD34-negative, CD56-positive, CD117-positive, CD122-positive,and CD161-positive.
has related synonym: p-NK

prostate stem cell
type: Class
equivalent class: Class
  intersection of: stem cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002367
subclass of: multi fate stem cell
subclass of: basal cell of prostate epithelium
IAO_0000115: A prostate epithelial cell that is CD133-positive, CD44-positive, integrin A2beta3-high. This cell is a stem cell for the prostate epithelium.
has exact synonym: CD133-positive prostate epithelial cell

basal cell of prostate epithelium
type: Class
subclass of: epithelial cell of prostate
IAO_0000115: An undifferentiated cell of the prostate epithelium that lacks secretory activity.

CD56-negative, CD161-positive immature natural killer cell, human
type: Class
equivalent class: Class
  intersection of: immature natural killer cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001003
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001024
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001381
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001874
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002065
  intersection of: Restriction
    on property: RO_0002162
    some values from: NCBITaxon 9606
subclass of: immature natural killer cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001003
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001024
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001381
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001874
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002065
subclass of: Restriction
  on property: RO_0002162
  some values from: NCBITaxon 9606
IAO_0000115: A natural killer cell that is developmentally immature, has the phenotype CD34-negative, CD56-negative, CD117-positive, CD122-positive,and CD161-positive.
has related synonym: p-NK

Dx5-negative, NK1.1-positive immature natural killer cell, mouse
type: Class
equivalent class: Class
  intersection of: immature natural killer cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001008
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002977
  intersection of: Restriction
    on property: RO_0002162
    some values from: NCBITaxon_10090
subclass of: immature natural killer cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001008
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002977
subclass of: Restriction
  on property: RO_0002162
  some values from: NCBITaxon_10090
IAO_0000115: An immature natural killer cell that is NK1.1-positive and DX-5 negative.

endocardial cell
type: Class
equivalent class: Class
  intersection of: endothelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002165
subclass of: CL_0010008
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002165
IAO_0000115: An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin.
has exact synonym: endocardial endothelial cell
has exact synonym: endothelial cell of endocardium

progenitor cell of endocrine pancreas
type: Class
subclass of: CL_0011026
IAO_0000115: A progenitor cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1.
has exact synonym: pancreatic endocrine progenitor
has exact synonym: pancreatic islet progenitor cell

gestational hematopoietic stem cell
type: Class
equivalent class: Class
  intersection of: hematopoietic stem cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000922
subclass of: hematopoietic stem cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000922
IAO_0000115: A hematopoietic stem cell that exists during embryogenesis.

fetal liver hematopoietic progenitor cell
type: Class
equivalent class: Class
  intersection of: gestational hematopoietic stem cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001308
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001896
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0042611
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001006
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001833
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001932
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002037
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002979
subclass of: gestational hematopoietic stem cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0002107
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001308
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001896
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0042611
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001006
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001833
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001932
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002037
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002979
IAO_0000115: A hematopoietic stem cell that resides in the fetal liver. In mice, this cell type is first observed at E10.5. This cell type is MHC-positive, HSA-positive, AA4.1-positive, CD45-positive, Sca-1 positive, CD150-positive, CD48-negative and CD244-negative.

yolk sac hematopoietic stem cell
type: Class
equivalent class: Class
  intersection of: gestational hematopoietic stem cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0042611
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001006
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002979
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001307
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001932
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002037
subclass of: gestational hematopoietic stem cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001040
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0042611
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001006
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002979
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001307
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001932
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002037
IAO_0000115: A hematopoietic stem found in the yolk sac. In mice, this cell type is Sca-1-negative, CD45-negative, MHC-negative, HSA-positive, AA4.1-positive, CD44-positive.
has exact synonym: hemangioblast precursor

primitive red blood cell
type: Class
equivalent class: Class
  intersection of: primitive erythroid lineage cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000922
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000008467
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000008857
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0000586
subclass of: primitive erythroid lineage cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000922
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000008467
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000008857
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0000586
subclass of: Restriction
  on property: RO_0002202
  some values from: primitive erythroid progenitor
IAO_0000115: A large nucleated basophilic erythrocyte found in mammalian embryos. This cell type arises from the blood islands of yolk sacs and expresses different types of hemoglobins (beta-H1, gamma-1 and zeta) than adult erythrocytes. Considered a type of erythroblast as this cell type can enucleate in circulation.
has exact synonym: primitive erythroblast
has exact synonym: primitive erythrocyte
has exact synonym: primitive erythroid cell

primitive reticulocyte
type: Class
equivalent class: Class
  intersection of: primitive erythroid lineage cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0000586
  intersection of: Restriction
    on property: RO_0002202
    some values from: primitive red blood cell
subclass of: primitive erythroid lineage cell
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0000586
subclass of: Restriction
  on property: RO_0002202
  some values from: primitive red blood cell
IAO_0000115: A primitive erythrocyte that has undergone enucleation. This cell type is 3-6 fold bigger than the fetal derived erythrocytes that they co-circulate with during fetal development. Expresses epsilon-gamma hemoglobin chains.
has exact synonym: megalocyte

fetal derived definitive erythrocyte
type: Class
equivalent class: Class
  intersection of: enucleate erythrocyte
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000922
  intersection of: Restriction
    on property: BFO_0000051
    some values from: PR_000008857
subclass of: enucleate erythrocyte
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000922
subclass of: Restriction
  on property: BFO_0000051
  some values from: PR_000008857
subclass of: Restriction
  on property: RO_0002202
  some values from: fetal liver hematopoietic progenitor cell
IAO_0000115: A fetal liver derived enucleated erythrocyte. This erythrocyte resembles adult erythrocytes in that they are small (3- to 6- times smaller than primitive erythrocytes) and produce adult hemaglobins.
has exact synonym: macrocyte

pyrenocyte
type: Class
equivalent class: Class
  intersection of: primitive erythroid lineage cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0000587
  intersection of: Restriction
    on property: RO_0002202
    some values from: primitive red blood cell
subclass of: primitive erythroid lineage cell
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0000587
subclass of: Restriction
  on property: RO_0002202
  some values from: primitive red blood cell
IAO_0000115: Derived from the Greek word pyren (the pit of a stone fruit), this is a transient nucleated cell type that results from exclusion of the nucleus from the primitive erythrocyte.

placental hematopoietic stem cell
type: Class
equivalent class: Class
  intersection of: hematopoietic stem cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001987
subclass of: gestational hematopoietic stem cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001987
IAO_0000115: A hematopoietic stem cell of the placenta. This cell type is first observed E10.5 This cell type may give rise to fetal liver hematopoietic stem cells.

primitive erythroid progenitor
type: Class
equivalent class: Class
  intersection of: primitive erythroid lineage cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000009127
subclass of: primitive erythroid lineage cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000009127
subclass of: Restriction
  on property: RO_0002202
  some values from: hemangioblast
IAO_0000115: A progenitor cell that is capable of forming colonies of primitive erythrocytes in the blood island of the yolk sac. First arrive at E7.5 in mouse and expresses CD41.
has exact synonym: EryP-CFC
has exact synonym: inner blood island hemangioblast

cerebellar granule cell precursor
type: Class
subclass of: neuroblast (sensu Vertebrata)
subclass of: neural cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0009841
IAO_0000115: A cell located in the outermost proliferative zone of the external germinal layer that can differentiate into astroglial cells and granule cells. This cell type is glial fibrillary acidic protein-positive and HNK1-positive.
has broad synonym: granule cell precursor
has broad synonym: granule cell progenitor
has related synonym: GCP

keratocyte
type: Class
equivalent class: Class
  intersection of: fibroblast
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001777
subclass of: neural crest derived fibroblast
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001777
IAO_0000115: A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic morphology; located between the lamellae with a large flattened nucleus, and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratan sulfate.
has exact synonym: corneal fibroblast
has exact synonym: corneal keratocyte

trabecular meshwork cell
type: Class
equivalent class: Class
  intersection of: endothelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0005969
subclass of: endothelial cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0005969
IAO_0000115: A cell that lines the trabecular meshwork, which is an area of tissue in the eye located around the base of the cornea, near the ciliary body, and is responsible for draining the aqueous humor from the eye via the anterior chamber (the chamber on the front of the eye covered by the cornea). This cell may play a role in regulating intraocular pressure.
has exact synonym: trabeculocyte

respiratory epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0004802
subclass of: endo-epithelial cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0004802
IAO_0000115: An endo-epithelial cell of the respiratory tract.
has exact synonym: airway epithelial cell

fungal spore
type: Class
subclass of: fungal cell
IAO_0000115: A differentiated form of a fungus produced during or as a result of an asexual or sexual reproductive process; usually a cell with a thick cell wall that stores and protects one or more nuclei. Spores may be produced in response to, and are characteristically resistant to, adverse environmental conditions.

respiratory goblet cell
type: Class
equivalent class: Class
  intersection of: goblet cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0004802
subclass of: goblet cell
subclass of: respiratory epithelial cell
IAO_0000115: A simple columnar epithelial cell that secretes mucin. Rough endoplasmic reticulum, mitochondria, the nucleus, and other organelles are concentrated in the basal portion. The apical plasma membrane projects microvilli to increase surface area for secretion.
has exact synonym: respiratory mucosa goblet cells

myotube
type: Class
equivalent class: Class
  intersection of: muscle cell
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0030017
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001908
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0002478
subclass of: multinucleate cell
subclass of: striated muscle cell
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0002478
IAO_0000115: A transversely striated, synctial muscle cell, formed by the fusion of myoblasts.
has exact synonym: myotubule
has exact synonym: single cell sarcomere

ear hair cell
type: Class
equivalent class: Class
  intersection of: sensory hair cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001690
subclass of: neuronal receptor cell
subclass of: sensory hair cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001690
IAO_0000115: A hair cell of the ear that contains the organs of balance and hearing.
has exact synonym: ear receptor cell

Schwann cell precursor
type: Class
subclass of: glioblast
subclass of: CL_0011026
subclass of: Restriction
  on property: RO_0002202
  some values from: migratory neural crest cell
IAO_0000115: A glioblast cell that develops from a migratory neural crest cell. The SCP is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has no basal lamina. In rodents SCPs are the only cells in the Schwann cell linage that expresses Cdh19.
has exact synonym: Schwann cell precursor cell

immature Schwann cell
type: Class
subclass of: CL_0002573
subclass of: Restriction
  on property: RO_0002202
  some values from: Schwann cell precursor
IAO_0000115: A glial cell that develops from a Schwann cell precursor. The immature Schwann cell is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has a basal lamina. Cells can survive without an axon present. Immature Schwann cell can be found communally ensheathing large groups of axons.
has broad synonym: Schwann cell

blastoconidium
type: Class
subclass of: macroconidium
IAO_0000115: An oblong or round asexual spore formed from conidial chains.
has related synonym: blastospore

arthroconidium
type: Class
subclass of: macroconidium
IAO_0000115: Cylindrical spore formed by development and compartmentation of hyphae; the hyphae are often supporting blastoconidiophores.
has related synonym: arthrospore

intermediate monocyte
type: Class
equivalent class: Class
  intersection of: monocyte
  intersection of: Restriction
    on property: has_not_completed
    some values from: GO_0030224
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001002
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001199
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001289
subclass of: monocyte
subclass of: Restriction
  on property: has_not_completed
  some values from: GO_0030224
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001002
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001199
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001289
subclass of: Restriction
  on property: RO_0002202
  some values from: classical monocyte
IAO_0000115: A monocyte that has characteristics of both patrolling and inflammatory monocytes.

Gr1-high classical monocyte
type: Class
equivalent class: Class
  intersection of: classical monocyte
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001014
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001206
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001879
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001012
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002062
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000002980
subclass of: classical monocyte
subclass of: CD115-positive monocyte
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001014
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001206
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001879
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000002980
IAO_0000115: A resident monocyte that is Gr-1 high, CD43-negative, CX3CR1-negative, CD115-positive, and B220-negative.

CD14-low, CD16-positive monocyte
type: Class
equivalent class: Class
  intersection of: non-classical monocyte
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001483
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001889
subclass of: non-classical monocyte
subclass of: CD14-positive monocyte
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001483
subclass of: Restriction
  on property: RO_0002202
  some values from: CD14-positive, CD16-positive monocyte
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001889
IAO_0000115: A patrolling monocyte that is CD14-low and CD16-positive.
has exact synonym: non-classical monocyte, human

CD14-positive, CD16-positive monocyte
type: Class
equivalent class: Class
  intersection of: CD14-positive monocyte
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001199
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001483
subclass of: CD14-positive monocyte
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001199
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001483
IAO_0000115: A CD14-positive monocyte that is also CD16-positive and CCR2-negative.
has exact synonym: CD16+ monocyte

Gr1-positive, CD43-positive monocyte
type: Class
equivalent class: Class
  intersection of: monocyte
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001012
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001879
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002062
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002980
subclass of: CD115-positive monocyte
subclass of: intermediate monocyte
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001879
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002980
subclass of: Restriction
  on property: RO_0002202
  some values from: Gr1-high classical monocyte
IAO_0000115: An intermediate monocyte that is Gr1-positive, CD43-positive.

fraction B/C precursor B cell
type: Class
equivalent class: Class
  intersection of: precursor B cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0071753
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001002
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001879
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001932
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002037
subclass of: precursor B cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001879
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001932
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002037
IAO_0000115: A precursor B cell that is AA4-positive, IgM-negative, CD19-positive, CD43-positive and HSA-positive.

mature dendritic epithelial T cell precursor
type: Class
subclass of: fetal thymocyte
subclass of: Restriction
  on property: RO_0002202
  some values from: immature dendritic epithelial T cell precursor
IAO_0000115: A thymocyte that has a T cell receptor consisting of a gamma chain that has as part a Vgamma3 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-negative. This cell-type is found in the fetal thymus with highest numbers occurring at E17-E18.
has exact synonym: mature DEC precursor
has exact synonym: mature DETC precursor

Peyer's patch B cell
type: Class
equivalent class: Class
  intersection of: mature B cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001211
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001839
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001879
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002037
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0071753
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001014
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001289
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001338
subclass of: B-2 B cell
subclass of: CL_0009014
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001839
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002037
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0071753
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001014
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001338
IAO_0000115: A resting mature B cell within the Peyer's patch that is CD19-positive, B220-positive, IgM-positive, AA4-negative, CD23-positive, CD43-negative, and CD5-negative.
has exact synonym: Peyers patch B cell

fetal thymocyte
type: Class
subclass of: thymocyte
IAO_0000115: A thymocyte found in the fetal thymus.

gamma-delta thymocyte
type: Class
equivalent class: Class
  intersection of: thymocyte
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000025402
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0042106
subclass of: gamma-delta T cell
subclass of: double negative thymocyte
IAO_0000115: A post-natal thymocyte expressing components of the gamma-delta T cell receptor. This cell type is always double-negative (i.e. CD4-negative, CD8-negative).
has exact synonym: gammadelta thymocyte
has exact synonym: gd thymocyte

pancreatic stellate cell
type: Class
subclass of: fibroblast
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001264
IAO_0000115: A cell that is found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and has long cytoplasmic processes that encircle the base of the acinus. Expresses several intermediate filament proteins including vimentin and nestin. Shares many of the characteristics of hepatatic stellate cells, but not stellate cells of the central nervous system. Upon activation, this cell type undergoes morphological and gene expression changes that make the cell suggestive of being a type of myofibroblast.
has exact synonym: PaSC
has exact synonym: pancreas stellate cell

primitive erythroid lineage cell
type: Class
subclass of: erythroid lineage cell
IAO_0000115: An immature or mature cell of the first erythroid lineage to arise during embryonic development.

hemangioblast
type: Class
subclass of: BFO_0000002
subclass of: mesodermal cell
subclass of: Restriction
  on property: RO_0002202
  some values from: yolk sac hematopoietic stem cell
IAO_0000115: A pluripotent cell in the yolk sac that can give rise to mesenchymal cells including erythrocytes and endothelial cells.

mature T cell
type: Class
equivalent class: Class
  intersection of: T cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0042101
  intersection of: Restriction
    on property: RO_0002353
    some values from: GO_0045058
subclass of: T cell
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0042101
subclass of: Restriction
  on property: RO_0002353
  some values from: GO_0045058
IAO_0000115: A T cell that expresses a T cell receptor complex and has completed T cell selection.
has exact synonym: CD3e-positive T cell
has exact synonym: mature T-cell
has related synonym: CD3epsilon T cell

immature T cell
type: Class
equivalent class: Class
  intersection of: T cell
  intersection of: Restriction
    on property: has_not_completed
    some values from: GO_0045058
subclass of: T cell
subclass of: Restriction
  on property: has_not_completed
  some values from: GO_0045058
IAO_0000115: A T cell that has not completed T cell selection.
has exact synonym: immature T-cell

nucleated reticulocyte
type: Class
equivalent class: Class
  intersection of: reticulocyte
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0002505
subclass of: reticulocyte
subclass of: nucleate cell
IAO_0000115: A reticulocyte that retains the nucleus and other organelles. Found in birds, fish, amphibians and reptiles.

enucleated reticulocyte
type: Class
equivalent class: Class
  intersection of: reticulocyte
  intersection of: Restriction
    on property: BFO_0000051
    some values from: GO_0005840
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0001405
subclass of: anucleate cell
subclass of: reticulocyte
subclass of: Restriction
  on property: BFO_0000051
  some values from: GO_0005840
IAO_0000115: A reticulocyte lacking a nucleus and showing a basophilic reticulum under vital staining due to the presence of ribosomes.

DN2a thymocyte
type: Class
equivalent class: Class
  intersection of: DN2 thymocyte
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000002065
subclass of: DN2 thymocyte
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000002065
IAO_0000115: A DN2 thymocyte that is Kit-hi.

DN2b thymocyte
type: Class
equivalent class: Class
  intersection of: DN2 thymocyte
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000002065
subclass of: DN2 thymocyte
subclass of: Restriction
  on property: RO_0002202
  some values from: DN2a thymocyte
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000002065
IAO_0000115: A DN2 thymocyte that is Kit-low.

early T lineage precursor
type: Class
equivalent class: Class
  intersection of: pro-T cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001380
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001307
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001869
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002065
subclass of: pro-T cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001380
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001307
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001869
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002065
IAO_0000115: A pro-T cell that is lin-negative, CD25-negative, CD127-negative, CD44-positive and kit-positive.
has exact synonym: ETP
has exact synonym: preT.ETP.Th

resting double-positive thymocyte
type: Class
equivalent class: Class
  intersection of: double-positive, alpha-beta thymocyte
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0000587
subclass of: double-positive, alpha-beta thymocyte
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0000587
IAO_0000115: A double-positive, alpha-beta thymocyte that is small and not proliferating.
has exact synonym: T.DP.sm.Th

double-positive blast
type: Class
equivalent class: Class
  intersection of: double-positive, alpha-beta thymocyte
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0000586
  intersection of: Restriction
    on property: RO_0000056
    some values from: GO_0008283
subclass of: double-positive, alpha-beta thymocyte
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0000586
subclass of: Restriction
  on property: RO_0000056
  some values from: GO_0008283
subclass of: Restriction
  on property: RO_0002202
  some values from: resting double-positive thymocyte
IAO_0000115: A double-positive thymocyte that is large (i.e. has a high forward scatter signal in flow cytometry) and is actively proliferating.
has exact synonym: T.DPb.Th
has exact synonym: activated double-positive thymocyte

CD69-positive double-positive thymocyte
type: Class
equivalent class: Class
  intersection of: double-positive, alpha-beta thymocyte
  intersection of: Restriction
    on property: RO_0000056
    some values from: GO_0043368
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001343
  intersection of: Restriction
    on property: RO_0015016
    some values from: GO_0042105
subclass of: double-positive, alpha-beta thymocyte
subclass of: Restriction
  on property: RO_0000056
  some values from: GO_0043368
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001343
subclass of: Restriction
  on property: RO_0002202
  some values from: double-positive blast
subclass of: Restriction
  on property: RO_0015016
  some values from: GO_0042105
IAO_0000115: A double-positive thymocyte that is CD69-positive and has begun positive selection.
has exact synonym: T.DP69+.Th

CD4-intermediate, CD8-positive double-positive thymocyte
type: Class
equivalent class: Class
  intersection of: double-positive, alpha-beta thymocyte
  intersection of: Restriction
    on property: RO_0000056
    some values from: GO_0043368
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001343
  intersection of: Restriction
    on property: RO_0015015
    some values from: GO_0042105
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001004
subclass of: double-positive, alpha-beta thymocyte
subclass of: Restriction
  on property: RO_0000056
  some values from: GO_0043368
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001343
subclass of: Restriction
  on property: RO_0002202
  some values from: CD69-positive double-positive thymocyte
subclass of: Restriction
  on property: RO_0015015
  some values from: GO_0042105
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001004
IAO_0000115: A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD4 co-receptor.
has exact synonym: T.4int8+.Th
has exact synonym: T_4int8+_Th

CD4-positive, CD8-intermediate double-positive thymocyte
type: Class
equivalent class: Class
  intersection of: double-positive, alpha-beta thymocyte
  intersection of: Restriction
    on property: RO_0000056
    some values from: GO_0043368
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001343
  intersection of: Restriction
    on property: RO_0015015
    some values from: GO_0042105
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000025402
subclass of: double-positive, alpha-beta thymocyte
subclass of: Restriction
  on property: RO_0000056
  some values from: GO_0043368
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001343
subclass of: Restriction
  on property: RO_0002202
  some values from: CD69-positive double-positive thymocyte
subclass of: Restriction
  on property: RO_0015015
  some values from: GO_0042105
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000025402
IAO_0000115: A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD8 co-receptor.
has exact synonym: T.4+8int.Th
has exact synonym: T_4+8int_Th

CD24-positive, CD4 single-positive thymocyte
type: Class
equivalent class: Class
  intersection of: CD4-positive, alpha-beta thymocyte
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001932
  intersection of: Restriction
    on property: RO_0015015
    some values from: GO_0042105
subclass of: CD4-positive, alpha-beta thymocyte
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001932
subclass of: Restriction
  on property: RO_0002202
  some values from: CD69-positive, CD4-positive single-positive thymocyte
subclass of: Restriction
  on property: RO_0015015
  some values from: GO_0042105
IAO_0000115: A CD4-positive, CD8-negative thymocyte that is CD24-positive and expresses high levels of the alpha-beta T cell receptor.
has exact synonym: CD24-positive, CD4 single-positive semimature thymocyte
has exact synonym: T.4SP24int.Th

CD69-positive, CD4-positive single-positive thymocyte
type: Class
equivalent class: Class
  intersection of: CD4-positive, alpha-beta thymocyte
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001343
  intersection of: Restriction
    on property: RO_0015015
    some values from: GO_0042105
subclass of: CD4-positive, alpha-beta thymocyte
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001343
subclass of: Restriction
  on property: RO_0002202
  some values from: CD4-positive, CD8-intermediate double-positive thymocyte
subclass of: Restriction
  on property: RO_0015015
  some values from: GO_0042105
IAO_0000115: A CD4-positive, CD8-negative thymocyte that expresses high levels of the alpha-beta T cell receptor and is CD69-positive.
has exact synonym: T.4SP69+.Th
has exact synonym: intermediate CD4-single-positive

CD24-positive, CD8 single-positive thymocyte
type: Class
equivalent class: Class
  intersection of: CD8-positive, alpha-beta thymocyte
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001932
  intersection of: Restriction
    on property: RO_0015015
    some values from: GO_0042105
subclass of: CD8-positive, alpha-beta thymocyte
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001932
subclass of: Restriction
  on property: RO_0002202
  some values from: CD69-positive, CD8-positive single-positive thymocyte
subclass of: Restriction
  on property: RO_0015015
  some values from: GO_0042105
IAO_0000115: A CD8-positive, CD4-negative thymocyte that is CD24-positive and expresses high levels of the alpha-beta T cell receptor.
has exact synonym: CD24-positive, CD8 single-positive semimature thymocyte
has exact synonym: T.8SP24int.Th

CD69-positive, CD8-positive single-positive thymocyte
type: Class
equivalent class: Class
  intersection of: CD8-positive, alpha-beta thymocyte
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001343
  intersection of: Restriction
    on property: RO_0015015
    some values from: GO_0042105
subclass of: CD8-positive, alpha-beta thymocyte
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001343
subclass of: Restriction
  on property: RO_0002202
  some values from: CD4-intermediate, CD8-positive double-positive thymocyte
subclass of: Restriction
  on property: RO_0015015
  some values from: GO_0042105
IAO_0000115: A CD8-positive, CD4-negative thymocyte that expresses high levels of the alpha-beta T cell receptor and is CD69-positive.
has exact synonym: T.8SP69+.Th
has exact synonym: intermediate CD8-single-positive

mature CD4 single-positive thymocyte
type: Class
equivalent class: Class
  intersection of: CD4-positive, alpha-beta T cell
  intersection of: Restriction
    on property: RO_0015015
    some values from: GO_0042105
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001932
subclass of: CD4-positive, alpha-beta T cell
subclass of: Restriction
  on property: RO_0002202
  some values from: CD24-positive, CD4 single-positive thymocyte
subclass of: Restriction
  on property: RO_0015015
  some values from: GO_0042105
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001932
IAO_0000115: A mature CD4-positive, CD8-negative alpha-beta T cell found in the thymus that is CD24-low and has high expression of the T cell receptor.
has related synonym: T.4SP24-.Th

mature CD8 single-positive thymocyte
type: Class
equivalent class: Class
  intersection of: CD8-positive, alpha-beta T cell
  intersection of: Restriction
    on property: RO_0015015
    some values from: GO_0042105
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000001932
subclass of: CD8-positive, alpha-beta T cell
subclass of: Restriction
  on property: RO_0002202
  some values from: CD24-positive, CD8 single-positive thymocyte
subclass of: Restriction
  on property: RO_0015015
  some values from: GO_0042105
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000001932
IAO_0000115: A mature CD8-positive, CD4-negative alpha-beta T cell found in the thymus that is CD24-low and has high expression of the T cell receptor.
has exact synonym: T.8SP24-.Th

oligodendrocyte precursor cell
type: Class
subclass of: neuron associated cell (sensu Vertebrata)
subclass of: CL_0011026
subclass of: Class
  intersection of: neuron associated cell (sensu Vertebrata)
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001017
subclass of: Restriction
  on property: RO_0002202
  some values from: glioblast (sensu Vertebrata)
IAO_0000115: A progenitor cell of the central nervous system that can differentiate into oligodendrocytes or type-2 astrocytes. This cell originates from multiple structures within the developing brain including the medial ganglion eminence and the lateral ganglionic eminence. These cells migrate throughout the central nervous system and persist into adulthood where they play an important role in remyelination of injured neurons.
has broad synonym: oligodendrocyte-type 2 astrocyte (O-2A) progenitor cell
has broad synonym: oligodendrocyte/type-2 astrocyte progenitor cell
has related synonym: O-2A/OPC
has related synonym: O2A/OPC

Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell
type: Class
equivalent class: Class
  intersection of: CD11b-positive dendritic cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
subclass of: CD11b-positive dendritic cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
IAO_0000115: Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell is a conventional dendritic cell that is CD11b-positive, CD4-negative, CD8_alpha-negative and is CD205-positive.
has exact synonym: DC.8-4-11b+
has exact synonym: spleen double-negative dendritic cell

CD8_alpha-negative plasmacytoid dendritic cell
type: Class
equivalent class: Class
  intersection of: CD11c-low plasmacytoid dendritic cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001004
subclass of: CD11c-low plasmacytoid dendritic cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001004
IAO_0000115: A CD11c-low plasmacytoid dendritic cell that is CD8alpha-negative and CD4-positive.
has exact synonym: DC.pDC.8-

CD8_alpha-positive plasmacytoid dendritic cell
type: Class
equivalent class: Class
  intersection of: CD11c-low plasmacytoid dendritic cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001004
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001084
subclass of: CD11c-low plasmacytoid dendritic cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001004
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001084
IAO_0000115: A CD11c-low plasmacytoid dendritic cell that is CD8alpha-positive and CD4-positive.
has exact synonym: DC.pDC.8+

epidermal Langerhans cell
type: Class
equivalent class: Class
  intersection of: Langerhans cell
  intersection of: Restriction
    on property: RO_0001025
    some values from: UBERON_0001003
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0042613
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001012
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001014
subclass of: Langerhans cell
subclass of: CD11b-positive dendritic cell
subclass of: Restriction
  on property: RO_0001025
  some values from: UBERON_0001003
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0042613
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001014
IAO_0000115: A Langerhans cell that is in the epidermis and is CD45-positive, MHCII-positive, and CD11b-positive.

CD8alpha-negative thymic conventional dendritic cell
type: Class
equivalent class: Class
  intersection of: thymic conventional dendritic cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
subclass of: thymic conventional dendritic cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
IAO_0000115: A conventional thymic dendritic cell that is CD8alpha-negative.
has exact synonym: DC.8-.Th

adipose dendritic cell
type: Class
equivalent class: Class
  intersection of: conventional dendritic cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0001013
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001813
subclass of: myeloid leukocyte
subclass of: conventional dendritic cell
subclass of: connective tissue cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001013
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001813
subclass of: Restriction
  on property: RO_0002202
  some values from: pre-conventional dendritic cell
IAO_0000115: A F4/80-negative dendritic cell located in adipose tissue.

SIRPa-positive adipose dendritic cell
type: Class
equivalent class: Class
  intersection of: conventional dendritic cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001968
subclass of: adipose dendritic cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001968
IAO_0000115: An adipose dendritic cell that is SIRPa-positive.
has exact synonym: DC.SIRPa+.Ad

SIRPa-negative adipose dendritic cell
type: Class
equivalent class: Class
  intersection of: conventional dendritic cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001968
subclass of: adipose dendritic cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001968
IAO_0000115: An adipose dendritic cell that is SIRPa-negative.
has exact synonym: DC.SIRPa-.Ad

CD11b-positive dendritic cell
type: Class
equivalent class: Class
  intersection of: conventional dendritic cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001012
subclass of: conventional dendritic cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001012
IAO_0000115: A conventional dendritic cell that expresses CD11b (ITGAM).

Gr1-high myeloid suppressor cell
type: Class
equivalent class: Class
  intersection of: myeloid suppressor cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001013
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000002980
subclass of: myeloid suppressor cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001013
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000002980
IAO_0000115: A myeloid suppressor cell that is Gr1-high and CD11c-negative.
has exact synonym: MDS.Gr1hi

Gr1-low myeloid suppressor cell
type: Class
equivalent class: Class
  intersection of: myeloid suppressor cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001013
  intersection of: Restriction
    on property: RO_0015016
    some values from: PR_000002980
subclass of: myeloid suppressor cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001013
subclass of: Restriction
  on property: RO_0015016
  some values from: PR_000002980
IAO_0000115: A myeloid suppressor cell that is Gr1-low and CD11c-positive.
has exact synonym: MDS.Gr1lo

MHC-II-negative classical monocyte
type: Class
equivalent class: Class
  intersection of: Gr1-high classical monocyte
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0042613
subclass of: Gr1-high classical monocyte
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0042613
IAO_0000115: Gr1-high monocyte that lacks MHC-II receptor complex.
has exact synonym: Mo.6C+II-

MHC-II-positive classical monocyte
type: Class
equivalent class: Class
  intersection of: Gr1-high classical monocyte
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0042613
subclass of: Gr1-high classical monocyte
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0042613
IAO_0000115: Gr1-high monocyte that has a MHC-II receptor complex.
has exact synonym: Mo.6c+II

MHC-II-negative non-classical monocyte
type: Class
equivalent class: Class
  intersection of: Gr1-low non-classical monocyte
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0042613
subclass of: Gr1-low non-classical monocyte
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0042613
IAO_0000115: Gr1-low non-classical monocyte that lacks expression of a MHC-II complex.
has exact synonym: Mo.6C-II-

MHC-II-low non-classical monocyte
type: Class
equivalent class: Class
  intersection of: Gr1-low non-classical monocyte
  intersection of: Restriction
    on property: RO_0015016
    some values from: GO_0042613
subclass of: Gr1-low non-classical monocyte
subclass of: Restriction
  on property: RO_0015016
  some values from: GO_0042613
IAO_0000115: Gr1-low non-classical monocyte that has low to intermediate expression of the MHC-II complex.
has exact synonym: Mo.6C-IIint

MHC-II-high non-classical monocyte
type: Class
equivalent class: Class
  intersection of: Gr1-low non-classical monocyte
  intersection of: Restriction
    on property: RO_0015015
    some values from: GO_0042613
subclass of: Gr1-low non-classical monocyte
subclass of: Restriction
  on property: RO_0015015
  some values from: GO_0042613
IAO_0000115: Gr1-low non-classical monocyte that has high surface expression of a MHC-II complex.
has exact synonym: Mo.6C-II+

lymphoid MHC-II-negative classical monocyte
type: Class
equivalent class: Class
  intersection of: MHC-II-negative classical monocyte
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001013
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001813
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001012
subclass of: MHC-II-negative classical monocyte
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001013
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001813
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001012
IAO_0000115: A MHC-II-negative classical monocyte located in lymphoid tissue that is F4/80-positive, CD11c-negative, and CD11b-high.

lymphoid MHC-II-negative non-classical monocyte
type: Class
equivalent class: Class
  intersection of: MHC-II-negative non-classical monocyte
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001013
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001813
  intersection of: Restriction
    on property: RO_0015015
    some values from: PR_000001012
subclass of: MHC-II-negative non-classical monocyte
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001013
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001813
subclass of: Restriction
  on property: RO_0015015
  some values from: PR_000001012
IAO_0000115: A MHC-II-negative classical monocyte located in lymphoid tissue that is F4/80-positive, CD11c-intermediate, and CD11b-high.

bone marrow macrophage
type: Class
equivalent class: Class
  intersection of: tissue-resident macrophage
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001014
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001020
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000002980
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001813
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000002062
subclass of: tissue-resident macrophage
subclass of: CL_0010004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001014
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001020
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000002980
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001813
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000002062
IAO_0000115: A tissue-resident macrophage located in the bone marrow. This cell type is B220-negative, CD3e-negative, Ly-6C-negative, CD115-positive, F4/80-positive.
has related synonym: MF.BM

adipose macrophage
type: Class
equivalent class: Class
  intersection of: tissue-resident macrophage
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001006
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001013
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001968
subclass of: tissue-resident macrophage
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001006
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001013
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001968
IAO_0000115: A macrophage located in adipose tissue that is CD45-positive, CD11c-positive, and SIRPa-positive.

F4/80-negative adipose macrophage
type: Class
equivalent class: Class
  intersection of: adipose macrophage
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001813
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0042613
subclass of: adipose macrophage
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001813
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0042613
IAO_0000115: An adipose macrophage that does not express F4/80but is MHC-II-positive. This cell type exhibits autofluorescence under typical flow cyometry conditions.
has exact synonym: MF.Autofl.Ad

F4/80-positive adipose macrophage
type: Class
equivalent class: Class
  intersection of: adipose macrophage
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: GO_0042613
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001813
subclass of: adipose macrophage
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: GO_0042613
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001813
IAO_0000115: An adipose macrophage that does not express MHC-II but is F4/80-positive.
has exact synonym: MF.F480+.Ad

hair follicle melanocyte
type: Class
equivalent class: Class
  intersection of: melanocyte
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002073
subclass of: CL_0002559
subclass of: CL_2000000
IAO_0000115: A melanocyte that produces pigment within the hair follicle.

epithelial melanocyte
type: Class
equivalent class: Class
  intersection of: melanocyte
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000483
subclass of: melanocyte
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000483
IAO_0000115: A melanocyte that produces pigment in the epithelium.

retinal melanocyte
type: Class
equivalent class: Class
  intersection of: melanocyte
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000966
subclass of: melanocyte
subclass of: CL_0009004
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000966
IAO_0000115: A melanocyte of the retina. This cell type is distinct from pigmented retinal epithelium.

trophoblast giant cell
type: Class
equivalent class: Class
  intersection of: trophoblast cell
  intersection of: Restriction
    on property: RO_0000053
    some values from: PATO_0000586
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0001974
subclass of: trophoblast cell
subclass of: Restriction
  on property: RO_0000053
  some values from: PATO_0000586
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0001974
IAO_0000115: A trophoblast cell that has a large volume of cytoplasm, is polyploid and is usually mononuclear but is also occasionally multi-nucleate. This cell type is important in establishing maternal physiology and remodeling of the vasculature of the placenta.
has exact synonym: giant trophoblast cell

double negative thymocyte
type: Class
equivalent class: Class
  intersection of: thymocyte
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000025402
subclass of: thymocyte
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000025402
IAO_0000115: A thymocyte that lacks expression of CD4 and CD8.
has exact synonym: CD4-CD8- T cell
has exact synonym: double negative T cell

auditory epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0050910
subclass of: sensory epithelial cell
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0050910
IAO_0000115: A specialized cell involved in auditory sensory perception.

cardiocyte
type: Class
equivalent class: Class
  intersection of: cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0007100
subclass of: cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0007100
IAO_0000115: A cell located in the heart, including both muscle and non muscle cells.
has exact synonym: heart cell

intraepithelial lymphocyte
type: Class
equivalent class: Class
  intersection of: mature T cell
  intersection of: Restriction
    on property: RO_0001025
    some values from: UBERON_0001277
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0002385
subclass of: mature T cell
subclass of: Restriction
  on property: RO_0001025
  some values from: UBERON_0001277
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0002385
IAO_0000115: A T cell that is located in the intestinal epithelium and is capable of a mucosal immune response.
has exact synonym: IEL
has exact synonym: intraepithelial T cell
has exact synonym: intraepithelial T-cell

spongiotrophoblast cell
type: Class
subclass of: trophoblast cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0004021
IAO_0000115: A trophoblast cell that arises in the junctional zone (basal plate) of the placenta.
has exact synonym: spongiotrophoblast

enteric smooth muscle cell
type: Class
equivalent class: Class
  intersection of: smooth muscle cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000160
subclass of: smooth muscle cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000160
IAO_0000115: A smooth muscle cell of the intestine.
has exact synonym: intestinal smooth muscle cell

langerin-positive lymph node dendritic cell
type: Class
equivalent class: Class
  intersection of: conventional dendritic cell
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001004
  intersection of: Restriction
    on property: lacks_plasma_membrane_part
    some values from: PR_000001084
  intersection of: Restriction
    on property: RO_0002104
    some values from: GO_0042613
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001293
subclass of: conventional dendritic cell
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001004
subclass of: Restriction
  on property: lacks_plasma_membrane_part
  some values from: PR_000001084
subclass of: Restriction
  on property: RO_0002104
  some values from: GO_0042613
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001293
IAO_0000115: A dermal dendritic cell isolated from skin draining lymph nodes that is langerin-positive, MHC-II-positive, and CD4-negative and CD8a-negative.

kidney epithelial cell
type: Class
equivalent class: Class
  intersection of: epithelial cell
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0002113
subclass of: epithelial cell
subclass of: CL_1000497
IAO_0000115: An epithelial cell of the kidney.

nephrocyte
type: Class
subclass of: eukaryotic cell
subclass of: renal filtration cell
subclass of: Restriction
  on property: RO_0002160
  some values from: NCBITaxon_50557
IAO_0000115: An insect excretory cell that regulates hemolymph composition by filtration and filtrate endocytosis.

renal filtration cell
type: Class
subclass of: excretory cell
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0001008
IAO_0000115: A renal filtration cell is a specialized cell of the renal system that filter fluids by charge, size or both.

mesonephric podocyte
type: Class
equivalent class: Class
  intersection of: podocyte
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000080
subclass of: podocyte
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000080
IAO_0000115: A specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the mesonephros.
has exact synonym: mesonephric glomerular visceral epithelial cell

disseminated nephrocyte
type: Class
subclass of: nephrocyte
IAO_0000115: A disseminated nephrocyte is a nephrocyte that filters hemolymph and is found at scattered locations in the fat body or other tissues.

metanephric podocyte
type: Class
equivalent class: Class
  intersection of: podocyte
  intersection of: Restriction
    on property: BFO_0000050
    some values from: UBERON_0000081
subclass of: podocyte
subclass of: Restriction
  on property: BFO_0000050
  some values from: UBERON_0000081
IAO_0000115: A specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the metanephros.
has exact synonym: metanephric glomerular visceral epithelial cell

CD16-positive myeloid dendritic cell
type: Class
equivalent class: Class
  intersection of: myeloid dendritic cell
  intersection of: Restriction
    on property: RO_0002104
    some values from: PR_000001483
  intersection of: Restriction
    on property: RO_0002215
    some values from: GO_0032640
subclass of: myeloid dendritic cell
subclass of: Restriction
  on property: RO_0002104
  some values from: PR_000001483
subclass of: Restriction
  on property: RO_0002215
  some values from: GO_0032640
IAO_0000115: A myeloid dendritic cell found in the blood that is CD16-positive.
has exact synonym: CD16+ mDC
has exact synonym: CD16-mDC

immature CD16-positive myeloid dendritic cell
type: Class
equivalent class: Class
  intersection of: CD16-positive myeloid dendritic cell
subclass of: immature conventional dendritic cell
subclass of: CD16-positive myeloid dendritic cell
IAO_0000115: An immature CD16-positive myeloid dendritic cell is CD80-low, CD86-low, and MHCII-low.