format-version: 1.2 data-version: go/2024-12-18/subsets/gocheck_obsoletion_candidate.owl subsetdef: chebi_ph7_3 "Rhea list of ChEBI terms representing the major species at pH 7.3." subsetdef: gocheck_do_not_annotate "Term not to be used for direct annotation" subsetdef: gocheck_obsoletion_candidate "Terms planned for obsoletion" subsetdef: goslim_agr "AGR slim" subsetdef: goslim_aspergillus "Aspergillus GO slim" subsetdef: goslim_candida "Candida GO slim" subsetdef: goslim_chembl "ChEMBL protein targets summary" subsetdef: goslim_drosophila "Drosophila GO slim" subsetdef: goslim_euk_cellular_processes_ribbon "GO ribbon for eukaroytic cellular processes" subsetdef: goslim_flybase_ribbon "Insecta GO ribbon slim" subsetdef: goslim_generic "Generic GO slim" subsetdef: goslim_metagenomics "Metagenomics GO slim" subsetdef: goslim_mouse "Mouse GO slim" subsetdef: goslim_pir "PIR GO slim" subsetdef: goslim_plant "Plant GO slim" subsetdef: goslim_plant_ribbon "Plant GO ribbon" subsetdef: goslim_pombe "Fission yeast GO slim" subsetdef: goslim_prokaryote "GO subset for prokaryotes" subsetdef: goslim_prokaryote_ribbon "Prokaryote GO ribbon slim" subsetdef: goslim_synapse "synapse GO slim" subsetdef: goslim_virus "GO subset for viruses" subsetdef: goslim_yeast "Yeast GO slim" synonymtypedef: syngo_official_label "label approved by the SynGO project" synonymtypedef: systematic_synonym "Systematic synonym" EXACT ontology: go/subsets/gocheck_obsoletion_candidate property_value: owl:versionInfo "2024-12-18" xsd:string [Term] id: GO:0000079 name: regulation of cyclin-dependent protein serine/threonine kinase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity." [GOC:go_curators, GOC:pr] subset: gocheck_obsoletion_candidate synonym: "regulation of CDK activity" EXACT [] synonym: "regulation of cyclin-dependent protein kinase activity" BROAD [] is_a: GO:0071900 ! regulation of protein serine/threonine kinase activity [Term] id: GO:0000413 name: protein peptidyl-prolyl isomerization namespace: biological_process def: "The modification of a protein by cis-trans isomerization of a proline residue." [GOC:krc, PMID:16959570] subset: gocheck_obsoletion_candidate synonym: "protein proline isomerization" EXACT [] is_a: GO:0018208 ! peptidyl-proline modification [Term] id: GO:0001932 name: regulation of protein phosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein." [GOC:hjd] subset: gocheck_obsoletion_candidate synonym: "regulation of protein amino acid phosphorylation" EXACT [GOC:bf] is_a: GO:0042325 ! regulation of phosphorylation relationship: regulates GO:0006468 ! protein phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI [Term] id: GO:0001933 name: negative regulation of protein phosphorylation namespace: biological_process def: "Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein." [GOC:hjd] subset: gocheck_obsoletion_candidate synonym: "down regulation of protein amino acid phosphorylation" EXACT [] synonym: "down-regulation of protein amino acid phosphorylation" EXACT [] synonym: "downregulation of protein amino acid phosphorylation" EXACT [] synonym: "inhibition of protein amino acid phosphorylation" NARROW [] synonym: "negative regulation of protein amino acid phosphorylation" EXACT [GOC:bf] is_a: GO:0001932 ! regulation of protein phosphorylation is_a: GO:0031400 ! negative regulation of protein modification process is_a: GO:0042326 ! negative regulation of phosphorylation relationship: negatively_regulates GO:0006468 ! protein phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI [Term] id: GO:0001934 name: positive regulation of protein phosphorylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein." [GOC:hjd] subset: gocheck_obsoletion_candidate synonym: "activation of protein amino acid phosphorylation" NARROW [] synonym: "positive regulation of protein amino acid phosphorylation" EXACT [GOC:bf] synonym: "stimulation of protein amino acid phosphorylation" NARROW [] synonym: "up regulation of protein amino acid phosphorylation" EXACT [] synonym: "up-regulation of protein amino acid phosphorylation" EXACT [] synonym: "upregulation of protein amino acid phosphorylation" EXACT [] is_a: GO:0001932 ! regulation of protein phosphorylation is_a: GO:0031401 ! positive regulation of protein modification process relationship: positively_regulates GO:0006468 ! protein phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27189" xsd:anyURI property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI [Term] id: GO:0001977 name: renal system process involved in regulation of blood volume namespace: biological_process def: "A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system." [GOC:dph, GOC:tb, ISBN:0721643949] subset: gocheck_obsoletion_candidate synonym: "renal blood volume control of blood pressure" RELATED [] synonym: "renal regulation of blood volume" RELATED [GOC:dph, GOC:tb] [Term] id: GO:0002030 name: inhibitory G protein-coupled receptor phosphorylation namespace: biological_process def: "The process that inhibits the signaling function of a G protein-coupled receptor by addition of a phosphate group to its third intracellular loop consensus site." [PMID:8396717] subset: gocheck_obsoletion_candidate synonym: "inhibitory G-protein coupled receptor phosphorylation" EXACT [] is_a: GO:0006468 ! protein phosphorylation [Term] id: GO:0002084 name: protein depalmitoylation namespace: biological_process def: "The removal of palymitoyl groups from a lipoprotein." [GOC:hjd] subset: gocheck_obsoletion_candidate is_a: GO:0035601 ! protein deacylation [Term] id: GO:0006468 name: protein phosphorylation namespace: biological_process def: "The process of introducing a phosphate group on to a protein." [GOC:hb] subset: gocheck_obsoletion_candidate subset: goslim_yeast synonym: "protein amino acid phosphorylation" EXACT [GOC:bf] is_a: GO:0016310 ! phosphorylation is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0006469 name: negative regulation of protein kinase activity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity." [GOC:go_curators] subset: gocheck_obsoletion_candidate synonym: "down regulation of protein kinase activity" EXACT [] synonym: "down-regulation of protein kinase activity" EXACT [] synonym: "downregulation of protein kinase activity" EXACT [] synonym: "inhibition of protein kinase activity" NARROW [] is_a: GO:0001933 ! negative regulation of protein phosphorylation is_a: GO:0033673 ! negative regulation of kinase activity is_a: GO:0045859 ! regulation of protein kinase activity [Term] id: GO:0006470 name: protein dephosphorylation namespace: biological_process def: "The process of removing one or more phosphoric residues from a protein." [GOC:hb] subset: gocheck_obsoletion_candidate subset: goslim_yeast synonym: "protein amino acid dephosphorylation" EXACT [GOC:bf] is_a: GO:0016311 ! dephosphorylation is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0006473 name: protein acetylation namespace: biological_process def: "The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "protein amino acid acetylation" EXACT [GOC:bf] is_a: GO:0043543 ! protein acylation [Term] id: GO:0006474 name: N-terminal protein amino acid acetylation namespace: biological_process def: "The acetylation of the N-terminal amino acid of proteins." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "N(alpha)-terminal acetylation" NARROW [PMID:11013267] is_a: GO:0006473 ! protein acetylation is_a: GO:0031365 ! N-terminal protein amino acid modification [Term] id: GO:0006475 name: internal protein amino acid acetylation namespace: biological_process def: "The addition of an acetyl group to a non-terminal amino acid in a protein." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0006473 ! protein acetylation [Term] id: GO:0006476 name: protein deacetylation namespace: biological_process def: "The removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "protein amino acid deacetylation" EXACT [GOC:bf] is_a: GO:0035601 ! protein deacylation [Term] id: GO:0006477 name: protein sulfation namespace: biological_process def: "The addition of a sulfate group as an ester to a protein amino acid." [GOC:curators] subset: gocheck_obsoletion_candidate synonym: "protein amino acid sulfation" EXACT [GOC:bf] synonym: "protein amino acid sulphation" EXACT [] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0006478 name: peptidyl-tyrosine sulfation namespace: biological_process def: "The sulfation of peptidyl-tyrosine residues to form peptidyl-O4'-sulfo-L-tyrosine." [RESID:AA0172] subset: gocheck_obsoletion_candidate synonym: "peptidyl-tyrosine sulphation" EXACT [] xref: RESID:AA0172 is_a: GO:0006477 ! protein sulfation is_a: GO:0018212 ! peptidyl-tyrosine modification [Term] id: GO:0006479 name: protein methylation namespace: biological_process def: "The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "protein amino acid methylation" EXACT [GOC:bf] xref: Reactome:R-HSA-8876725 "Protein methylation" is_a: GO:0008213 ! protein alkylation is_a: GO:0043414 ! macromolecule methylation [Term] id: GO:0006480 name: N-terminal protein amino acid methylation namespace: biological_process def: "The methylation of the N-terminal amino acid of a protein." [GOC:ai] subset: gocheck_obsoletion_candidate is_a: GO:0006479 ! protein methylation is_a: GO:0031365 ! N-terminal protein amino acid modification [Term] id: GO:0006481 name: C-terminal protein methylation namespace: biological_process def: "The methylation of the C-terminal amino acid of a protein." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "C-terminal protein amino acid methylation" EXACT [GOC:bf] is_a: GO:0006479 ! protein methylation is_a: GO:0018410 ! C-terminal protein amino acid modification [Term] id: GO:0006482 name: protein demethylation namespace: biological_process def: "The removal of a methyl group, from a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "protein amino acid demethylation" EXACT [GOC:bf] is_a: GO:0008214 ! protein dealkylation [Term] id: GO:0006497 name: protein lipidation namespace: biological_process alt_id: GO:0042050 def: "The covalent attachment of lipid groups to an amino acid in a protein." [GOC:jl] comment: For non-covalent interactions with a lipid, consider instead the term 'lipid binding ; GO:0008289' and its children. subset: gocheck_obsoletion_candidate subset: goslim_drosophila subset: goslim_yeast synonym: "lipid:protein modification" EXACT [] synonym: "protein amino acid lipidation" EXACT [GOC:bf] xref: RESID:AA0059 xref: RESID:AA0060 xref: RESID:AA0077 xref: RESID:AA0078 xref: RESID:AA0079 xref: RESID:AA0080 xref: RESID:AA0102 xref: RESID:AA0103 xref: RESID:AA0104 xref: RESID:AA0106 xref: RESID:AA0107 xref: RESID:AA0158 xref: RESID:AA0159 xref: RESID:AA0160 xref: RESID:AA0161 xref: RESID:AA0162 xref: RESID:AA0163 xref: RESID:AA0166 xref: RESID:AA0223 xref: RESID:AA0290 xref: RESID:AA0307 xref: RESID:AA0308 xref: RESID:AA0309 xref: RESID:AA0316 is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0006498 name: N-terminal protein lipidation namespace: biological_process def: "The covalent attachment of a lipid group to the amino terminus of a protein." [GOC:jl] subset: gocheck_obsoletion_candidate is_a: GO:0006497 ! protein lipidation is_a: GO:0031365 ! N-terminal protein amino acid modification [Term] id: GO:0006499 name: N-terminal protein myristoylation namespace: biological_process def: "The covalent attachment of a myristoyl group to the N-terminal amino acid residue of a protein." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0006498 ! N-terminal protein lipidation is_a: GO:0018377 ! protein myristoylation [Term] id: GO:0006500 name: N-terminal protein palmitoylation namespace: biological_process def: "The covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0006498 ! N-terminal protein lipidation is_a: GO:0018345 ! protein palmitoylation [Term] id: GO:0006501 name: C-terminal protein lipidation namespace: biological_process def: "The covalent attachment of a lipid group to the carboxy-terminus of a protein." [GOC:jl] subset: gocheck_obsoletion_candidate xref: Reactome:R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" is_a: GO:0006497 ! protein lipidation is_a: GO:0018410 ! C-terminal protein amino acid modification [Term] id: GO:0006517 name: protein deglycosylation namespace: biological_process def: "The removal of sugar residues from a glycosylated protein." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "glycoprotein deglycosylation" EXACT [] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0007171 name: activation of transmembrane receptor protein tyrosine kinase activity namespace: biological_process def: "Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "transmembrane receptor protein tyrosine kinase activation" RELATED [GOC:dph, GOC:tb] synonym: "transmembrane receptor protein tyrosine kinase dimerization" RELATED [GOC:dph, GOC:mtg_lung] is_a: GO:0032147 ! activation of protein kinase activity [Term] id: GO:0007175 name: negative regulation of epidermal growth factor-activated receptor activity namespace: biological_process alt_id: GO:0007177 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of EGF-activated receptor activity." [GOC:go_curators] subset: gocheck_obsoletion_candidate synonym: "down regulation of epidermal growth factor receptor activity" EXACT [] synonym: "down-regulation of epidermal growth factor receptor activity" EXACT [] synonym: "downregulation of epidermal growth factor receptor activity" EXACT [] synonym: "EGF receptor downregulation" EXACT [] synonym: "inhibition of epidermal growth factor receptor activity" NARROW [] synonym: "negative regulation of EGF receptor activity" EXACT [] synonym: "negative regulation of EGFR activity" EXACT [] synonym: "negative regulation of epidermal growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] is_a: GO:0007176 ! regulation of epidermal growth factor-activated receptor activity is_a: GO:0061099 ! negative regulation of protein tyrosine kinase activity is_a: GO:2000272 ! negative regulation of signaling receptor activity property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI [Term] id: GO:0007176 name: regulation of epidermal growth factor-activated receptor activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of EGF-activated receptor activity." [GOC:dph, GOC:go_curators] subset: gocheck_obsoletion_candidate synonym: "regulation of EGF receptor activity" EXACT [] synonym: "regulation of EGFR activity" EXACT [] synonym: "regulation of epidermal growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] is_a: GO:0010469 ! regulation of signaling receptor activity is_a: GO:0061097 ! regulation of protein tyrosine kinase activity [Term] id: GO:0007190 name: activation of adenylate cyclase activity namespace: biological_process def: "Any process that initiates the activity of the inactive enzyme adenylate cyclase." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "adenylate cyclase activation" EXACT [GOC:dph, GOC:tb] synonym: "adenylate cyclase activator" RELATED [] synonym: "adenylyl cyclase activation" EXACT [] xref: Reactome:R-HSA-187024 "NGF-independant TRKA activation" is_a: GO:0045762 ! positive regulation of adenylate cyclase activity [Term] id: GO:0007194 name: negative regulation of adenylate cyclase activity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity." [GOC:go_curators] subset: gocheck_obsoletion_candidate synonym: "adenylate cyclase inhibitor" RELATED [] synonym: "down regulation of adenylate cyclase activity" EXACT [] synonym: "down-regulation of adenylate cyclase activity" EXACT [] synonym: "downregulation of adenylate cyclase activity" EXACT [] synonym: "inhibition of adenylate cyclase activity" NARROW [] synonym: "negative regulation of adenylyl cyclase activity" EXACT [] is_a: GO:0045761 ! regulation of adenylate cyclase activity is_a: GO:0051350 ! negative regulation of lyase activity [Term] id: GO:0007250 name: activation of NF-kappaB-inducing kinase activity namespace: biological_process def: "The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues." [GOC:jl, PMID:12773372] subset: gocheck_obsoletion_candidate synonym: "activation of NIK activity" EXACT [GOC:bf] synonym: "positive regulation of NF-kappaB-inducing kinase activity" BROAD [] is_a: GO:0032147 ! activation of protein kinase activity [Term] id: GO:0007252 name: I-kappaB phosphorylation namespace: biological_process def: "The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription." [GOC:bf, GOC:jl, PMID:21772278, PMID:7594468] subset: gocheck_obsoletion_candidate synonym: "IkappaB phosphorylation" EXACT [GOC:bf] synonym: "IKB phosphorylation" EXACT [GOC:bf] synonym: "inhibitor of kappaB phosphorylation" EXACT [GOC:bf] synonym: "inhibitor of NF-kappaB phosphorylation" EXACT [GOC:bf] is_a: GO:0006468 ! protein phosphorylation [Term] id: GO:0007258 name: JUN phosphorylation namespace: biological_process def: "The process of introducing a phosphate group into a JUN protein." [GOC:jl] subset: gocheck_obsoletion_candidate is_a: GO:0006468 ! protein phosphorylation [Term] id: GO:0007260 name: tyrosine phosphorylation of STAT protein namespace: biological_process alt_id: GO:0042502 alt_id: GO:0042503 alt_id: GO:0042504 alt_id: GO:0042505 alt_id: GO:0042506 alt_id: GO:0042507 alt_id: GO:0042508 def: "The process of introducing a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:jl, PMID:10918594] subset: gocheck_obsoletion_candidate synonym: "tyrosine phosphorylation of Stat1 protein" NARROW [] synonym: "tyrosine phosphorylation of Stat2 protein" NARROW [] synonym: "tyrosine phosphorylation of Stat3 protein" NARROW [] synonym: "tyrosine phosphorylation of Stat4 protein" NARROW [] synonym: "tyrosine phosphorylation of Stat5 protein" NARROW [] synonym: "tyrosine phosphorylation of Stat6 protein" NARROW [] synonym: "tyrosine phosphorylation of Stat7 protein" NARROW [] is_a: GO:0018108 ! peptidyl-tyrosine phosphorylation [Term] id: GO:0008213 name: protein alkylation namespace: biological_process def: "The addition of an alkyl group to a protein amino acid. Alkyl groups are derived from alkanes by removal of one hydrogen atom." [GOC:ma] subset: gocheck_obsoletion_candidate subset: goslim_yeast synonym: "protein amino acid alkylation" EXACT [GOC:bf] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0008214 name: protein dealkylation namespace: biological_process def: "The removal of an alkyl group from a protein amino acid. Alkyl groups are derived from alkanes by removal of one hydrogen atom." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "protein amino acid dealkylation" EXACT [GOC:bf] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0008612 name: peptidyl-lysine modification to peptidyl-hypusine namespace: biological_process alt_id: GO:0046515 def: "The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine." [GOC:ma, ISBN:0198547684, RESID:AA0116] subset: gocheck_obsoletion_candidate synonym: "hypusine anabolism" EXACT [] synonym: "hypusine anabolism from peptidyl-lysine" EXACT [] synonym: "hypusine biosynthesis" EXACT [] synonym: "hypusine biosynthetic process" EXACT [] synonym: "hypusine biosynthetic process from peptidyl-lysine" EXACT [] synonym: "hypusine formation" EXACT [] synonym: "hypusine formation from peptidyl-lysine" EXACT [] synonym: "hypusine synthesis" EXACT [] synonym: "hypusine synthesis from peptidyl-lysine" EXACT [] synonym: "hypusinylation" EXACT [] synonym: "protein hypusination" EXACT [] xref: Reactome:R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" xref: RESID:AA0116 is_a: GO:0018205 ! peptidyl-lysine modification [Term] id: GO:0009249 name: protein lipoylation namespace: biological_process alt_id: GO:0018055 def: "The lipoylation of peptidyl-lysine to form peptidyl-N6-lipoyl-L-lysine." [RESID:AA0118] subset: gocheck_obsoletion_candidate synonym: "peptidyl-lysine lipoylation" EXACT [] synonym: "protein-lipoic acid cofactor linkage" EXACT [] xref: Reactome:R-HSA-9857492 "Protein lipoylation" is_a: GO:0018205 ! peptidyl-lysine modification [Term] id: GO:0010359 name: regulation of anion channel activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of anion channel activity." [PMID:17319842] subset: gocheck_obsoletion_candidate is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity [Term] id: GO:0010360 name: negative regulation of anion channel activity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity." [PMID:17319842] subset: gocheck_obsoletion_candidate is_a: GO:0010359 ! regulation of anion channel activity is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity [Term] id: GO:0010466 name: negative regulation of peptidase activity namespace: biological_process def: "Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0051346 ! negative regulation of hydrolase activity is_a: GO:0052547 ! regulation of peptidase activity [Term] id: GO:0010469 name: regulation of signaling receptor activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "regulation of receptor activity" BROAD [] synonym: "regulation of signalling receptor activity" EXACT [] is_a: GO:0065009 ! regulation of molecular function [Term] id: GO:0010517 name: regulation of phospholipase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0051336 ! regulation of hydrolase activity [Term] id: GO:0010518 name: positive regulation of phospholipase activity namespace: biological_process def: "Any process that increases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0010517 ! regulation of phospholipase activity is_a: GO:0060193 ! positive regulation of lipase activity [Term] id: GO:0010519 name: negative regulation of phospholipase activity namespace: biological_process def: "Any process that decreases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0010517 ! regulation of phospholipase activity is_a: GO:0060192 ! negative regulation of lipase activity [Term] id: GO:0010692 name: regulation of alkaline phosphatase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0010921 ! regulation of phosphatase activity [Term] id: GO:0010693 name: negative regulation of alkaline phosphatase activity namespace: biological_process def: "Any process that decreases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0010692 ! regulation of alkaline phosphatase activity is_a: GO:0010923 ! negative regulation of phosphatase activity [Term] id: GO:0010694 name: positive regulation of alkaline phosphatase activity namespace: biological_process def: "Any process that increases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0010692 ! regulation of alkaline phosphatase activity is_a: GO:0010922 ! positive regulation of phosphatase activity [Term] id: GO:0010722 name: regulation of ferrochelatase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of ferrochelatase activity; catalysis of the reaction: protoporphyrin + Fe2+ = protoheme + 2 H+." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0050790 ! regulation of catalytic activity [Term] id: GO:0010731 name: protein glutathionylation namespace: biological_process def: "The protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage." [GOC:BHF, GOC:dph, GOC:rl, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "protein amino acid glutathionylation" EXACT [GOC:bf] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0010732 name: regulation of protein glutathionylation namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage." [GOC:BHF, GOC:dph, GOC:rl, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "regulation of protein amino acid glutathionylation" EXACT [GOC:bf] relationship: regulates GO:0010731 ! protein glutathionylation [Term] id: GO:0010733 name: positive regulation of protein glutathionylation namespace: biological_process def: "Any process that increases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage." [GOC:BHF, GOC:dph, GOC:rl, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "positive regulation of protein amino acid glutathionylation" EXACT [GOC:bf] is_a: GO:0010732 ! regulation of protein glutathionylation is_a: GO:0031401 ! positive regulation of protein modification process relationship: positively_regulates GO:0010731 ! protein glutathionylation [Term] id: GO:0010734 name: negative regulation of protein glutathionylation namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage." [GOC:BHF, GOC:dph, GOC:rl, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "negative regulation of protein amino acid glutathionylation" EXACT [GOC:bf] is_a: GO:0010732 ! regulation of protein glutathionylation is_a: GO:0031400 ! negative regulation of protein modification process relationship: negatively_regulates GO:0010731 ! protein glutathionylation [Term] id: GO:0010799 name: regulation of peptidyl-threonine phosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0001932 ! regulation of protein phosphorylation relationship: regulates GO:0018107 ! peptidyl-threonine phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI [Term] id: GO:0010800 name: positive regulation of peptidyl-threonine phosphorylation namespace: biological_process def: "Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0001934 ! positive regulation of protein phosphorylation is_a: GO:0010799 ! regulation of peptidyl-threonine phosphorylation relationship: positively_regulates GO:0018107 ! peptidyl-threonine phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI [Term] id: GO:0010801 name: negative regulation of peptidyl-threonine phosphorylation namespace: biological_process def: "Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0001933 ! negative regulation of protein phosphorylation is_a: GO:0010799 ! regulation of peptidyl-threonine phosphorylation relationship: negatively_regulates GO:0018107 ! peptidyl-threonine phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI [Term] id: GO:0010849 name: regulation of proton-transporting ATPase activity, rotational mechanism namespace: biological_process def: "Any process that modulates the rate of ATP hydrolysis by an ATPase. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "regulation of hydrogen ion transporting ATPase activity, rotational mechanism" EXACT [GOC:dph, GOC:tb] synonym: "regulation of V-type ATPase activity" BROAD [GOC:dph, GOC:tb] is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity is_a: GO:0043462 ! regulation of ATP-dependent activity [Term] id: GO:0010921 name: regulation of phosphatase activity namespace: biological_process def: "Any process that modulates the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing phosphate." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0051336 ! regulation of hydrolase activity relationship: regulates GO:0016311 ! dephosphorylation [Term] id: GO:0010922 name: positive regulation of phosphatase activity namespace: biological_process def: "Any process that increases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0010921 ! regulation of phosphatase activity is_a: GO:0051345 ! positive regulation of hydrolase activity relationship: positively_regulates GO:0016311 ! dephosphorylation [Term] id: GO:0010923 name: negative regulation of phosphatase activity namespace: biological_process def: "Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0010921 ! regulation of phosphatase activity is_a: GO:0051346 ! negative regulation of hydrolase activity relationship: negatively_regulates GO:0016311 ! dephosphorylation [Term] id: GO:0010925 name: positive regulation of inositol-polyphosphate 5-phosphatase activity namespace: biological_process def: "Any process that increases the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0010922 ! positive regulation of phosphatase activity [Term] id: GO:0010950 name: positive regulation of endopeptidase activity namespace: biological_process def: "Any process that increases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0010952 ! positive regulation of peptidase activity is_a: GO:0052548 ! regulation of endopeptidase activity created_by: tb creation_date: 2009-04-27T11:45:39Z [Term] id: GO:0010951 name: negative regulation of endopeptidase activity namespace: biological_process def: "Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate subset: goslim_chembl is_a: GO:0010466 ! negative regulation of peptidase activity is_a: GO:0052548 ! regulation of endopeptidase activity created_by: tb creation_date: 2009-04-27T11:47:01Z [Term] id: GO:0010952 name: positive regulation of peptidase activity namespace: biological_process def: "Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0051345 ! positive regulation of hydrolase activity is_a: GO:0052547 ! regulation of peptidase activity created_by: tb creation_date: 2009-04-27T11:54:32Z [Term] id: GO:0010956 name: negative regulation of calcidiol 1-monooxygenase activity namespace: biological_process def: "Any process that decreases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0032769 ! negative regulation of monooxygenase activity is_a: GO:0060558 ! regulation of calcidiol 1-monooxygenase activity created_by: tb creation_date: 2009-05-06T11:21:34Z [Term] id: GO:0010980 name: positive regulation of vitamin D 24-hydroxylase activity namespace: biological_process def: "Any process that increases the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0032770 ! positive regulation of monooxygenase activity created_by: tb creation_date: 2009-06-01T11:47:19Z [Term] id: GO:0010998 name: regulation of translational initiation by eIF2 alpha phosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha." [GOC:BHF, GOC:dph, GOC:hjd, GOC:tb] comment: Consider also annotating to 'eukaryotic translation initiation factor 2alpha kinase activity ; GO:0004694'. subset: gocheck_obsoletion_candidate synonym: "eIF2 alpha phosphorylation in response to stress" EXACT [GOC:bf] synonym: "regulation of translational initiation by eIF2 alpha phosphorylation in response to stress" EXACT [GOC:bf] is_a: GO:0006468 ! protein phosphorylation created_by: tb creation_date: 2009-06-10T11:27:47Z [Term] id: GO:0010999 name: regulation of eIF2 alpha phosphorylation by heme namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a result of heme levels." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate xref: Reactome:R-HSA-9648895 "Response of EIF2AK1 (HRI) to heme deficiency" is_a: GO:0001932 ! regulation of protein phosphorylation relationship: regulates GO:0010998 ! regulation of translational initiation by eIF2 alpha phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI created_by: tb creation_date: 2009-06-10T11:42:10Z [Term] id: GO:0016310 name: phosphorylation namespace: biological_process def: "The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide." [ISBN:0198506732] subset: gocheck_obsoletion_candidate subset: goslim_chembl subset: goslim_metagenomics xref: Wikipedia:Phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0016311 name: dephosphorylation namespace: biological_process def: "The process of removing one or more phosphoric (ester or anhydride) residues from a molecule." [ISBN:0198506732] subset: gocheck_obsoletion_candidate xref: Wikipedia:Dephosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0016598 name: protein arginylation namespace: biological_process alt_id: GO:0019130 def: "The conjugation of arginine to the N-terminal aspartate or glutamate of a protein; required for the degradation of the protein via the ubiquitin pathway." [PMID:17896865] subset: gocheck_obsoletion_candidate synonym: "protein amino acid arginylation" EXACT [] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0017003 name: protein-heme linkage namespace: biological_process def: "The covalent linkage of heme and a protein." [GOC:ma] subset: gocheck_obsoletion_candidate synonym: "protein-haem linkage" EXACT [] is_a: GO:0017006 ! protein-tetrapyrrole linkage [Term] id: GO:0017006 name: protein-tetrapyrrole linkage namespace: biological_process def: "The covalent linking of a tetrapyrrole to a protein." [GOC:ai] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0017007 name: protein-bilin linkage namespace: biological_process def: "The covalent linkage of bilin and a protein." [GOC:ai] subset: gocheck_obsoletion_candidate is_a: GO:0017006 ! protein-tetrapyrrole linkage [Term] id: GO:0017008 name: protein-phycobiliviolin linkage namespace: biological_process def: "The linkage of the chromophore phycobiliviolin to phycoerythrocyanin." [RESID:AA0258] subset: gocheck_obsoletion_candidate xref: RESID:AA0258 is_a: GO:0017007 ! protein-bilin linkage [Term] id: GO:0017009 name: protein-phycocyanobilin linkage namespace: biological_process def: "The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin." [RESID:AA0131] subset: gocheck_obsoletion_candidate xref: RESID:AA0131 is_a: GO:0017007 ! protein-bilin linkage [Term] id: GO:0017010 name: protein-phycourobilin linkage namespace: biological_process def: "The linkage of the chromophore phycourobilin to phycoerythrins." [RESID:AA0260] subset: gocheck_obsoletion_candidate xref: RESID:AA0260 is_a: GO:0017007 ! protein-bilin linkage [Term] id: GO:0017011 name: protein-phycoerythrobilin linkage namespace: biological_process def: "The linkage of the chromophore phycoerythrobilin to phycoerythrins." [RESID:AA0132, RESID:AA0259] subset: gocheck_obsoletion_candidate xref: RESID:AA0132 is_a: GO:0017007 ! protein-bilin linkage [Term] id: GO:0017012 name: protein-phytochromobilin linkage namespace: biological_process def: "The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin." [RESID:AA0133] subset: gocheck_obsoletion_candidate xref: RESID:AA0133 is_a: GO:0017007 ! protein-bilin linkage [Term] id: GO:0017013 name: protein flavinylation namespace: biological_process def: "The addition of a flavin group to a protein amino acid." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "protein amino acid flavinylation" EXACT [GOC:bf] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0017014 name: protein nitrosylation namespace: biological_process def: "The covalent addition of a nitric oxide group to an amino acid within a protein." [GOC:ai, PMID:20972426] subset: gocheck_obsoletion_candidate synonym: "protein amino acid nitrosylation" EXACT [GOC:bf] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0017185 name: peptidyl-lysine hydroxylation namespace: biological_process def: "The hydroxylation of peptidyl-lysine to form peptidyl-hydroxylysine." [GOC:ai] subset: gocheck_obsoletion_candidate is_a: GO:0018126 ! protein hydroxylation is_a: GO:0018205 ! peptidyl-lysine modification [Term] id: GO:0017187 name: peptidyl-glutamic acid carboxylation namespace: biological_process def: "The gamma-carboxylation of peptidyl-glutamic acid; catalyzed by the vitamin K dependent gamma-glutamyl carboxylase." [RESID:AA0032] comment: See also the molecular function term 'gamma-glutamyl carboxylase activity ; GO:0008488'. subset: gocheck_obsoletion_candidate xref: Reactome:R-HSA-159854 "Gamma-carboxylation, transport, and amino-terminal cleavage of proteins" xref: RESID:AA0032 is_a: GO:0018200 ! peptidyl-glutamic acid modification is_a: GO:0018214 ! protein carboxylation [Term] id: GO:0017190 name: N-terminal peptidyl-aspartic acid acetylation namespace: biological_process def: "The acetylation of the N-terminal aspartic acid of proteins; catalyzed by aspartate N-acetyltransferase." [RESID:AA0042] comment: See also the molecular function term 'aspartate N-acetyltransferase activity ; GO:0017188'. subset: gocheck_obsoletion_candidate xref: RESID:AA0042 is_a: GO:0006474 ! N-terminal protein amino acid acetylation is_a: GO:0018197 ! peptidyl-aspartic acid modification [Term] id: GO:0017192 name: N-terminal peptidyl-glutamine acetylation namespace: biological_process def: "The acetylation of a glutamine residue in protein to form the N5-methyl-L-glutamine derivative. The occurrence of this modification has not been confirmed. Its annotation in sequence databases is either due to the misidentification of 2-pyrrolidone-5-carboxylic acid, or to inappropriate homolog comparisons when proteolytic modification is more probable." [RESID:AA0045] subset: gocheck_obsoletion_candidate xref: RESID:AA0045 is_a: GO:0006474 ! N-terminal protein amino acid acetylation is_a: GO:0018199 ! peptidyl-glutamine modification [Term] id: GO:0017196 name: N-terminal peptidyl-methionine acetylation namespace: biological_process def: "The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionine." [RESID:AA0049] subset: gocheck_obsoletion_candidate xref: RESID:AA0049 is_a: GO:0006474 ! N-terminal protein amino acid acetylation is_a: GO:0018206 ! peptidyl-methionine modification [Term] id: GO:0018002 name: N-terminal peptidyl-glutamic acid acetylation namespace: biological_process def: "The acetylation of the N-terminal glutamic acid of proteins to form the derivate acetyl-glutamic acid." [RESID:AA0044] comment: See also the molecular function term 'aspartate N-acetyltransferase activity ; GO:0017188'. subset: gocheck_obsoletion_candidate xref: RESID:AA0044 is_a: GO:0006474 ! N-terminal protein amino acid acetylation is_a: GO:0018200 ! peptidyl-glutamic acid modification [Term] id: GO:0018003 name: peptidyl-lysine N6-acetylation namespace: biological_process def: "The acetylation of the peptidyl-lysine of proteins to form the derivative peptidyl-N6-acetyl-L-lysine." [RESID:AA0055] comment: See also the molecular function term 'tubulin N-acetyltransferase activity ; GO:0019799'. subset: gocheck_obsoletion_candidate xref: RESID:AA0055 is_a: GO:0018393 ! internal peptidyl-lysine acetylation [Term] id: GO:0018004 name: N-terminal protein formylation namespace: biological_process def: "The formylation of the N-terminal amino acid of proteins." [GOC:ai] subset: gocheck_obsoletion_candidate is_a: GO:0018256 ! protein formylation is_a: GO:0031365 ! N-terminal protein amino acid modification [Term] id: GO:0018008 name: N-terminal peptidyl-glycine N-myristoylation namespace: biological_process def: "The myristoylation of the N-terminal glycine of proteins to form the derivative N-myristoyl-glycine." [RESID:AA0059] subset: gocheck_obsoletion_candidate synonym: "N-terminal peptidyl-glycine N-myristylation" EXACT [] xref: RESID:AA0059 is_a: GO:0006499 ! N-terminal protein myristoylation is_a: GO:0018201 ! peptidyl-glycine modification [Term] id: GO:0018009 name: N-terminal peptidyl-L-cysteine N-palmitoylation namespace: biological_process def: "The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal cysteine residue to form N-palmitoyl-L-cysteine." [RESID:AA0060] subset: gocheck_obsoletion_candidate xref: RESID:AA0060 is_a: GO:0006500 ! N-terminal protein palmitoylation is_a: GO:0018198 ! peptidyl-cysteine modification [Term] id: GO:0018011 name: N-terminal peptidyl-alanine methylation namespace: biological_process def: "The methylation of the N-terminal alanine of proteins." [RESID:AA0061, RESID:AA0062] subset: gocheck_obsoletion_candidate xref: RESID:AA0061 xref: RESID:AA0062 is_a: GO:0006480 ! N-terminal protein amino acid methylation is_a: GO:0018194 ! peptidyl-alanine modification [Term] id: GO:0018012 name: N-terminal peptidyl-alanine trimethylation namespace: biological_process def: "The trimethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N,N,N-trimethyl-L-alanine." [RESID:AA0062] subset: gocheck_obsoletion_candidate xref: RESID:AA0062 is_a: GO:0018011 ! N-terminal peptidyl-alanine methylation [Term] id: GO:0018013 name: N-terminal peptidyl-glycine methylation namespace: biological_process def: "The methylation of the N-terminal glycine of proteins to form the derivative N-methylglycine." [RESID:AA0063] subset: gocheck_obsoletion_candidate xref: RESID:AA0063 is_a: GO:0006480 ! N-terminal protein amino acid methylation is_a: GO:0018201 ! peptidyl-glycine modification [Term] id: GO:0018016 name: N-terminal peptidyl-proline dimethylation namespace: biological_process def: "The methylation of the N-terminal proline of proteins to form the derivative N,N-dimethyl-L-proline." [RESID:AA0066] subset: gocheck_obsoletion_candidate xref: RESID:AA0066 is_a: GO:0035568 ! N-terminal peptidyl-proline methylation [Term] id: GO:0018021 name: peptidyl-histidine methylation namespace: biological_process def: "The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine) or peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine)." [RESID:AA0073, RESID:AA0317] subset: gocheck_obsoletion_candidate xref: RESID:AA0073 xref: RESID:AA0317 is_a: GO:0006479 ! protein methylation is_a: GO:0018202 ! peptidyl-histidine modification [Term] id: GO:0018022 name: peptidyl-lysine methylation namespace: biological_process def: "The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative." [GOC:ai] subset: gocheck_obsoletion_candidate is_a: GO:0006479 ! protein methylation is_a: GO:0018205 ! peptidyl-lysine modification [Term] id: GO:0018023 name: peptidyl-lysine trimethylation namespace: biological_process def: "The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine." [RESID:AA0074] subset: gocheck_obsoletion_candidate xref: RESID:AA0074 is_a: GO:0018022 ! peptidyl-lysine methylation [Term] id: GO:0018026 name: peptidyl-lysine monomethylation namespace: biological_process def: "The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine." [RESID:AA0076] subset: gocheck_obsoletion_candidate xref: RESID:AA0076 is_a: GO:0018022 ! peptidyl-lysine methylation [Term] id: GO:0018027 name: peptidyl-lysine dimethylation namespace: biological_process def: "The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine." [RESID:AA0075] subset: gocheck_obsoletion_candidate xref: RESID:AA0075 is_a: GO:0018022 ! peptidyl-lysine methylation [Term] id: GO:0018057 name: peptidyl-lysine oxidation namespace: biological_process def: "The oxidation of the terminal amino-methylene groups of peptidyl-L-lysine or peptidyl-5-hydroxy-L-lysine to aldehyde groups to form allysine or hydroxyallysine residues, respectively; these are intermediates in the formation of covalent cross-links between adjacent polypeptide chains in proteins such as collagens." [ISBN:0198547684, RESID:AA0121] subset: gocheck_obsoletion_candidate xref: RESID:AA0121 is_a: GO:0018158 ! protein oxidation is_a: GO:0018205 ! peptidyl-lysine modification [Term] id: GO:0018058 name: N-terminal protein amino acid deamination, from amino carbon namespace: biological_process def: "The oxidative deamination of the alpha carbon of an encoded N-terminal amino acid, to form pyruvic acid retaining an amide bond between its 1-carboxyl group and the adjacent residue. The pyruvate 2-oxo group may become an enzyme active site, or it may be reduced to an alcohol." [RESID:AA0127, RESID:AA0128, RESID:AA0129] subset: gocheck_obsoletion_candidate xref: RESID:AA0127 xref: RESID:AA0128 xref: RESID:AA0129 is_a: GO:0018198 ! peptidyl-cysteine modification is_a: GO:0018277 ! protein deamination is_a: GO:0031363 ! N-terminal protein amino acid deamination [Term] id: GO:0018063 name: cytochrome c-heme linkage namespace: biological_process def: "The linkage of cytochromes and other heme proteins to heme." [RESID:AA0134, RESID:AA0135] subset: gocheck_obsoletion_candidate synonym: "cytochrome c-haem linkage" EXACT [] xref: RESID:AA0134 xref: RESID:AA0135 is_a: GO:0017003 ! protein-heme linkage [Term] id: GO:0018070 name: peptidyl-serine phosphopantetheinylation namespace: biological_process def: "The phosphopantetheinylation of peptidyl-serine to form peptidyl-O-phosphopantetheine-L-serine." [RESID:AA0150] subset: gocheck_obsoletion_candidate xref: RESID:AA0150 is_a: GO:0018209 ! peptidyl-serine modification is_a: GO:0018215 ! protein phosphopantetheinylation [Term] id: GO:0018076 name: N-terminal peptidyl-lysine acetylation namespace: biological_process def: "The acetylation of the N-terminal lysine of proteins." [GOC:ai] subset: gocheck_obsoletion_candidate is_a: GO:0006474 ! N-terminal protein amino acid acetylation is_a: GO:0018394 ! peptidyl-lysine acetylation [Term] id: GO:0018094 name: protein polyglycylation namespace: biological_process def: "The addition of glycyl units covalently bound to the gamma carboxyl group peptidyl-glutamic acid." [RESID:AA0201] subset: gocheck_obsoletion_candidate xref: RESID:AA0201 is_a: GO:0018200 ! peptidyl-glutamic acid modification [Term] id: GO:0018095 name: protein polyglutamylation namespace: biological_process def: "The addition of one or more alpha-linked glutamyl units to the gamma carboxyl group of peptidyl-glutamic acid." [RESID:AA0202] subset: gocheck_obsoletion_candidate xref: RESID:AA0202 is_a: GO:0018200 ! peptidyl-glutamic acid modification [Term] id: GO:0018105 name: peptidyl-serine phosphorylation namespace: biological_process def: "The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine." [RESID:AA0037] subset: gocheck_obsoletion_candidate xref: RESID:AA0037 is_a: GO:0006468 ! protein phosphorylation is_a: GO:0018209 ! peptidyl-serine modification [Term] id: GO:0018106 name: peptidyl-histidine phosphorylation namespace: biological_process def: "The phosphorylation of peptidyl-histidine to form peptidyl-1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine) or peptidyl-3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine)." [RESID:AA0035, RESID:AA0036] subset: gocheck_obsoletion_candidate xref: RESID:AA0035 xref: RESID:AA0036 is_a: GO:0006468 ! protein phosphorylation is_a: GO:0018202 ! peptidyl-histidine modification [Term] id: GO:0018107 name: peptidyl-threonine phosphorylation namespace: biological_process def: "The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine." [RESID:AA0038] subset: gocheck_obsoletion_candidate xref: RESID:AA0038 is_a: GO:0006468 ! protein phosphorylation is_a: GO:0018210 ! peptidyl-threonine modification [Term] id: GO:0018108 name: peptidyl-tyrosine phosphorylation namespace: biological_process def: "The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine." [RESID:AA0039] subset: gocheck_obsoletion_candidate xref: RESID:AA0039 is_a: GO:0006468 ! protein phosphorylation is_a: GO:0018212 ! peptidyl-tyrosine modification [Term] id: GO:0018109 name: peptidyl-arginine phosphorylation namespace: biological_process def: "The phosphorylation of peptidyl-arginine to form omega-N-phospho-L-arginine." [RESID:AA0222] subset: gocheck_obsoletion_candidate xref: RESID:AA0222 is_a: GO:0006468 ! protein phosphorylation is_a: GO:0018195 ! peptidyl-arginine modification [Term] id: GO:0018117 name: protein adenylylation namespace: biological_process alt_id: GO:0018176 def: "The addition of an adenylyl group (adenosine 5'-monophosphate; AMP) to a protein amino acid." [GOC:ai, GOC:jsg, GOC:sart, PMID:21607083] subset: gocheck_obsoletion_candidate synonym: "protein adenylation" EXACT [] synonym: "protein amino acid adenylylation" EXACT [GOC:bf] synonym: "protein AMPylation" EXACT [GOC:jsg, GOC:sart, PMID:21607083] is_a: GO:0018175 ! protein nucleotidylation [Term] id: GO:0018119 name: peptidyl-cysteine S-nitrosylation namespace: biological_process def: "The covalent addition of a nitric oxide (NO) group to the sulphur (S) atom of a cysteine residue in a protein, to form peptidyl-S-nitrosyl-L-cysteine." [RESID:AA0230] subset: gocheck_obsoletion_candidate synonym: "protein S-nitrosylation" EXACT [PMID:20972426] synonym: "S-nitrosylation" EXACT [PMID:20972426] xref: RESID:AA0230 is_a: GO:0017014 ! protein nitrosylation is_a: GO:0018198 ! peptidyl-cysteine modification [Term] id: GO:0018125 name: peptidyl-cysteine methylation namespace: biological_process def: "The methylation of peptidyl-cysteine to form peptidyl-S-methyl-L-cysteine." [RESID:AA0234] subset: gocheck_obsoletion_candidate xref: RESID:AA0234 is_a: GO:0006479 ! protein methylation is_a: GO:0018198 ! peptidyl-cysteine modification [Term] id: GO:0018126 name: protein hydroxylation namespace: biological_process def: "The addition of a hydroxy group to a protein amino acid." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "protein amino acid hydroxylation" EXACT [GOC:bf] xref: Reactome:R-HSA-9629569 "Protein hydroxylation" is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018143 name: nucleic acid-protein covalent cross-linking namespace: biological_process def: "The formation of a covalent cross-link between a nucleic acid and a protein." [GOC:ma] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018144 name: RNA-protein covalent cross-linking namespace: biological_process def: "The formation of a covalent cross-link between RNA and a protein." [GOC:ma] subset: gocheck_obsoletion_candidate is_a: GO:0018143 ! nucleic acid-protein covalent cross-linking [Term] id: GO:0018149 name: peptide cross-linking namespace: biological_process def: "The formation of a covalent cross-link between or within protein chains." [GOC:jsg] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018153 name: isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine namespace: biological_process def: "The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glutamine to produce N6-(L-isoglutamyl)-L-lysine." [RESID:AA0124] subset: gocheck_obsoletion_candidate xref: RESID:AA0124 is_a: GO:0018199 ! peptidyl-glutamine modification is_a: GO:0018205 ! peptidyl-lysine modification is_a: GO:0018262 ! isopeptide cross-linking [Term] id: GO:0018158 name: protein oxidation namespace: biological_process def: "The modification of a protein amino acid by oxidation." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "protein amino acid oxidation" EXACT [GOC:bf] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018160 name: peptidyl-pyrromethane cofactor linkage namespace: biological_process alt_id: GO:0018354 alt_id: GO:0033035 def: "The covalent binding of a pyrromethane (dipyrrin) cofactor to protein via the sulfur atom of cysteine forming dipyrrolylmethanemethyl-L-cysteine." [RESID:AA0252] subset: gocheck_obsoletion_candidate synonym: "dipyrromethane cofactor binding" RELATED [GOC:jsg] synonym: "peptidyl-pyrromethane cofactor linkage via dipyrrolylmethanemethyl-L-cysteine" EXACT [GOC:jsg] xref: RESID:AA0252 is_a: GO:0018198 ! peptidyl-cysteine modification [Term] id: GO:0018171 name: peptidyl-cysteine oxidation namespace: biological_process def: "The oxidation of peptidyl-cysteine to peptidyl-L-cysteine sulfinic acid or peptidyl-L-cysteine sulfenic acid." [PMID:9586994, RESID:AA0205, RESID:AA0262] subset: gocheck_obsoletion_candidate xref: RESID:AA0205 xref: RESID:AA0262 is_a: GO:0018158 ! protein oxidation is_a: GO:0018198 ! peptidyl-cysteine modification [Term] id: GO:0018173 name: peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of peptidyl-1-thioglycine from other compounds, including peptidyl-glycine." [PMID:10660523, RESID:AA0265] subset: gocheck_obsoletion_candidate synonym: "peptidyl-1-thioglycine anabolism from peptidyl-glycine" EXACT [] synonym: "peptidyl-1-thioglycine formation from peptidyl-glycine" EXACT [] synonym: "peptidyl-1-thioglycine synthesis from peptidyl-glycine" EXACT [] xref: RESID:AA0265 is_a: GO:0018201 ! peptidyl-glycine modification [Term] id: GO:0018174 name: protein-heme P460 linkage namespace: biological_process def: "The linkage of protein to heme P460." [RESID:AA0266, RESID:AA0271] subset: gocheck_obsoletion_candidate synonym: "protein-haem P460 linkage" EXACT [] xref: RESID:AA0266 xref: RESID:AA0271 is_a: GO:0017003 ! protein-heme linkage [Term] id: GO:0018175 name: protein nucleotidylation namespace: biological_process def: "The addition of a nucleotide to a protein amino acid." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "protein amino acid nucleotidylation" EXACT [GOC:bf] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018177 name: protein uridylylation namespace: biological_process def: "The addition of phospho-uridine to a protein amino acid." [GOC:jsg] subset: gocheck_obsoletion_candidate synonym: "protein amino acid uridylylation" EXACT [GOC:bf] is_a: GO:0018175 ! protein nucleotidylation [Term] id: GO:0018184 name: protein polyamination namespace: biological_process def: "The modification of a protein amino acid by polyamination." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "protein amino acid polyamination" EXACT [GOC:bf] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018186 name: peroxidase-heme linkage namespace: biological_process def: "The covalent linkage of heme to peroxidase." [RESID:AA0279, RESID:AA0280] subset: gocheck_obsoletion_candidate synonym: "peroxidase-haem linkage" EXACT [] xref: RESID:AA0279 xref: RESID:AA0280 is_a: GO:0017003 ! protein-heme linkage [Term] id: GO:0018188 name: peptidyl-proline di-hydroxylation namespace: biological_process def: "The modification of peptidyl-proline to form trans-2,3-cis-3,4-dihydroxy-L-proline." [RESID:AA0282] subset: gocheck_obsoletion_candidate xref: RESID:AA0282 is_a: GO:0019511 ! peptidyl-proline hydroxylation [Term] id: GO:0018190 name: protein octanoylation namespace: biological_process def: "The modification of a protein amino acid by formation of an ester or amide with octanoic acid." [GOC:jsg] subset: gocheck_obsoletion_candidate synonym: "protein amino acid octanoylation" EXACT [GOC:bf] is_a: GO:0006497 ! protein lipidation is_a: GO:0043543 ! protein acylation [Term] id: GO:0018191 name: peptidyl-serine octanoylation namespace: biological_process def: "The octanoylation of peptidyl-serine to form peptidyl-O3-octanoyl-L-serine, typical of the protein ghrelin." [PMID:10604470, RESID:AA0290] subset: gocheck_obsoletion_candidate xref: RESID:AA0290 is_a: GO:0018190 ! protein octanoylation is_a: GO:0018209 ! peptidyl-serine modification [Term] id: GO:0018194 name: peptidyl-alanine modification namespace: biological_process def: "The modification of peptidyl-alanine." [GOC:go_curators] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018195 name: peptidyl-arginine modification namespace: biological_process def: "The modification of peptidyl-arginine." [GOC:go_curators] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018197 name: peptidyl-aspartic acid modification namespace: biological_process def: "The modification of peptidyl-aspartic acid." [GOC:ma] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018198 name: peptidyl-cysteine modification namespace: biological_process def: "The modification of peptidyl-cysteine." [GOC:go_curators] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018199 name: peptidyl-glutamine modification namespace: biological_process def: "The modification of peptidyl-glutamine." [GOC:go_curators] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018200 name: peptidyl-glutamic acid modification namespace: biological_process def: "The modification of peptidyl-glutamic acid." [GOC:go_curators] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018201 name: peptidyl-glycine modification namespace: biological_process def: "The modification of peptidyl-glycine." [GOC:go_curators] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018202 name: peptidyl-histidine modification namespace: biological_process def: "The modification of peptidyl-histidine." [GOC:ma] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018203 name: peptidyl-isoleucine modification namespace: biological_process def: "The modification of peptidyl-isoleucine." [GOC:go_curators] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018204 name: peptidyl-leucine modification namespace: biological_process def: "The modification of peptidyl-leucine." [GOC:go_curators] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018205 name: peptidyl-lysine modification namespace: biological_process def: "The modification of peptidyl-lysine." [GOC:go_curators] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018206 name: peptidyl-methionine modification namespace: biological_process def: "The modification of peptidyl-methionine." [GOC:go_curators] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018207 name: peptidyl-phenylalanine modification namespace: biological_process def: "The modification of peptidyl-phenylalanine." [GOC:go_curators] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018208 name: peptidyl-proline modification namespace: biological_process def: "The modification of peptidyl-proline." [GOC:go_curators] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018209 name: peptidyl-serine modification namespace: biological_process def: "The modification of peptidyl-serine." [GOC:go_curators] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018210 name: peptidyl-threonine modification namespace: biological_process def: "The modification of peptidyl-threonine." [GOC:go_curators] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018211 name: peptidyl-tryptophan modification namespace: biological_process def: "The chemical alteration of a tryptophan residue in a peptide." [GOC:isa_complete] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018212 name: peptidyl-tyrosine modification namespace: biological_process def: "The modification of peptidyl-tyrosine." [GOC:go_curators] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018213 name: peptidyl-valine modification namespace: biological_process def: "The modification of peptidyl-valine." [GOC:go_curators] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018214 name: protein carboxylation namespace: biological_process def: "The addition of a carboxy group to a protein amino acid." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "protein amino acid carboxylation" EXACT [GOC:bf] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018215 name: protein phosphopantetheinylation namespace: biological_process def: "The modification of a protein amino acid by phosphopantetheinylation." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "protein amino acid phosphopantetheinylation" EXACT [GOC:bf] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018216 name: peptidyl-arginine methylation namespace: biological_process alt_id: GO:0018017 def: "The addition of a methyl group to an arginine residue in a protein." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0006479 ! protein methylation is_a: GO:0018195 ! peptidyl-arginine modification [Term] id: GO:0018217 name: peptidyl-aspartic acid phosphorylation namespace: biological_process def: "The phosphorylation of peptidyl-aspartic acid." [GOC:jl] subset: gocheck_obsoletion_candidate is_a: GO:0006468 ! protein phosphorylation is_a: GO:0018197 ! peptidyl-aspartic acid modification [Term] id: GO:0018230 name: peptidyl-L-cysteine S-palmitoylation namespace: biological_process def: "The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form peptidyl-S-palmitoyl-L-cysteine." [RESID:AA0106] comment: Palmitoylation of a non-terminal cysteine residue always occurs on a sulfur (S) atom. subset: gocheck_obsoletion_candidate synonym: "peptidyl-cysteine S-palmitoylation" EXACT [] synonym: "peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [] synonym: "peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" EXACT [] synonym: "peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" EXACT [] synonym: "peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [] xref: RESID:AA0106 is_a: GO:0018198 ! peptidyl-cysteine modification is_a: GO:0018345 ! protein palmitoylation [Term] id: GO:0018240 name: protein S-linked glycosylation via cysteine namespace: biological_process def: "The glycosylation of protein via the sulfur atom of peptidyl-cysteine, forming S-glycosyl-L-cysteine." [RESID:AA0152] subset: gocheck_obsoletion_candidate synonym: "protein amino acid S-linked glycosylation via cysteine" EXACT [GOC:bf] xref: RESID:AA0152 is_a: GO:0018198 ! peptidyl-cysteine modification [Term] id: GO:0018246 name: protein-coenzyme A linkage namespace: biological_process def: "The formation of a linkage between a protein amino acid and coenzyme A." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018247 name: protein-phosphoribosyl dephospho-coenzyme A linkage namespace: biological_process def: "The linkage of phosphoribosyl dephospho-coenzyme A to protein via peptidyl-serine, to form O-(phosphoribosyl dephospho-coenzyme A)-L-serine; it is uncertain whether the phosphoribosyl glycosidic attachment to the dephospho-coenzyme A is alpha or beta, and through the 2' or the 3' position." [RESID:AA0167] subset: gocheck_obsoletion_candidate xref: RESID:AA0167 is_a: GO:0018209 ! peptidyl-serine modification is_a: GO:0018246 ! protein-coenzyme A linkage [Term] id: GO:0018249 name: protein dehydration namespace: biological_process def: "The removal of a water group from a protein amino acid." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "protein amino acid dehydration" EXACT [GOC:bf] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018251 name: peptidyl-tyrosine dehydrogenation namespace: biological_process def: "The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-dehydrotyrosine coupled with cyclization of neighboring residues." [RESID:AA0183] comment: See also the biological process terms 'peptide cross-linking via L-seryl-5-imidazolinone glycine ; GO:0018252' and 'peptide cross-linking via 2-imino-glutaminyl-5-imidazolinone glycine ; GO:0019729'. subset: gocheck_obsoletion_candidate xref: RESID:AA0183 is_a: GO:0018212 ! peptidyl-tyrosine modification is_a: GO:0018249 ! protein dehydration [Term] id: GO:0018256 name: protein formylation namespace: biological_process def: "The addition of a formyl group to a protein amino acid." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "protein amino acid formylation" EXACT [GOC:bf] is_a: GO:0043543 ! protein acylation [Term] id: GO:0018259 name: RNA-protein covalent cross-linking via peptidyl-serine namespace: biological_process def: "The formation of a covalent cross-link between RNA and a peptidyl-serine residue by the formation of O-(phospho-5'-5NA)-L-serine." [RESID:AA0213] subset: gocheck_obsoletion_candidate xref: RESID:AA0213 is_a: GO:0018144 ! RNA-protein covalent cross-linking is_a: GO:0018209 ! peptidyl-serine modification [Term] id: GO:0018260 name: protein guanylylation namespace: biological_process def: "The addition of phospho-guanosine to a protein amino acid." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "protein amino acid guanylylation" EXACT [GOC:bf] is_a: GO:0018175 ! protein nucleotidylation [Term] id: GO:0018262 name: isopeptide cross-linking namespace: biological_process def: "The formation of a covalent cross-link between or within peptide chains, where either the amino group or the carboxyl group, or both, are not attached to the alpha carbon." [GOC:jsg] subset: gocheck_obsoletion_candidate is_a: GO:0018149 ! peptide cross-linking [Term] id: GO:0018272 name: protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine namespace: biological_process def: "The modification of peptidyl-lysine to form N6-pyridoxal phosphate-L-lysine." [RESID:AA0119] subset: gocheck_obsoletion_candidate xref: RESID:AA0119 is_a: GO:0018205 ! peptidyl-lysine modification is_a: GO:0018352 ! protein-pyridoxal-5-phosphate linkage [Term] id: GO:0018277 name: protein deamination namespace: biological_process def: "The removal of an amino group from a protein amino acid." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "protein amino acid deamination" EXACT [GOC:bf] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018282 name: metal incorporation into metallo-sulfur cluster namespace: biological_process def: "The formation of a cluster of several metal atoms, including iron, nickel, molybdenum, vanadium, or copper, with one or more bridging (mu-bond) sulfur atoms; amino acids residues in proteins that may ligate the metal sulfur cluster are cysteine, histidine, aspartate, glutamate, serine and cysteine persulfide." [GOC:jsg] subset: gocheck_obsoletion_candidate synonym: "metal incorporation into metallo-sulphur cluster" EXACT [] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018283 name: iron incorporation into metallo-sulfur cluster namespace: biological_process def: "The incorporation of iron into a metallo-sulfur cluster." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "iron incorporation into metallo-sulphur cluster" EXACT [] is_a: GO:0018282 ! metal incorporation into metallo-sulfur cluster [Term] id: GO:0018289 name: molybdenum incorporation into metallo-sulfur cluster namespace: biological_process def: "The incorporation of molybdenum into a metallo-sulfur cluster." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "molybdenum incorporation into metallo-sulphur cluster" EXACT [] is_a: GO:0018282 ! metal incorporation into metallo-sulfur cluster [Term] id: GO:0018291 name: molybdenum incorporation into iron-sulfur cluster namespace: biological_process def: "The incorporation of molybdenum into an iron-sulfur cluster." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "molybdenum incorporation into iron-sulphur cluster" EXACT [] is_a: GO:0018289 ! molybdenum incorporation into metallo-sulfur cluster [Term] id: GO:0018293 name: protein-FAD linkage namespace: biological_process def: "The formation of a linkage between a protein amino acid and flavin-adenine dinucleotide (FAD)." [GOC:ai] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018315 name: molybdenum incorporation into molybdenum-molybdopterin complex namespace: biological_process alt_id: GO:0042041 def: "The incorporation of molybdenum into a molybdenum-molybdopterin complex." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "molybdenum incorporation into metallo-pterin complex" EXACT [] is_a: GO:0042040 ! metal incorporation into metallo-molybdopterin complex [Term] id: GO:0018316 name: peptide cross-linking via L-cystine namespace: biological_process def: "The oxidation of two peptidyl-cysteine residues to form a peptidyl-L-cystine (dicysteine) in which segments of peptide chain are linked by a disulfide bond; the cross-link may be between different or the same peptide chain." [RESID:AA0025] subset: gocheck_obsoletion_candidate xref: RESID:AA0025 is_a: GO:0018149 ! peptide cross-linking is_a: GO:0018198 ! peptidyl-cysteine modification [Term] id: GO:0018317 name: protein C-linked glycosylation via tryptophan namespace: biological_process def: "The glycosylation of a carbon atom of a peptidyl-tryptophan residue." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "protein amino acid C-linked glycosylation via tryptophan" EXACT [GOC:bf] is_a: GO:0018211 ! peptidyl-tryptophan modification [Term] id: GO:0018335 name: protein succinylation namespace: biological_process def: "The modification of a protein by the addition of a succinyl group (CO-CH2-CH2-CO) to an amino acid residue." [GOC:bf] subset: gocheck_obsoletion_candidate synonym: "protein amino acid succinylation" EXACT [GOC:bf] is_a: GO:0043543 ! protein acylation [Term] id: GO:0018336 name: peptidyl-tyrosine hydroxylation namespace: biological_process def: "The hydroxylation of peptidyl-tyrosine to form peptidyl-dihydroxyphenylalanine." [GOC:ai] subset: gocheck_obsoletion_candidate is_a: GO:0018126 ! protein hydroxylation [Term] id: GO:0018342 name: protein prenylation namespace: biological_process alt_id: GO:0018346 def: "The covalent attachment of a prenyl group to a protein; geranyl, farnesyl, or geranylgeranyl groups may be added." [GOC:di, ISBN:0198506732] subset: gocheck_obsoletion_candidate synonym: "C-terminal protein prenylation" NARROW [] synonym: "protein amino acid prenylation" EXACT [GOC:bf] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018343 name: protein farnesylation namespace: biological_process alt_id: GO:0018347 def: "The covalent attachment of a farnesyl group to a protein." [GOC:jl] subset: gocheck_obsoletion_candidate synonym: "C-terminal protein farnesylation" NARROW [] synonym: "protein amino acid farnesylation" EXACT [GOC:bf] is_a: GO:0018342 ! protein prenylation [Term] id: GO:0018344 name: protein geranylgeranylation namespace: biological_process alt_id: GO:0018348 def: "The covalent attachment of a geranylgeranyl group to a protein." [GOC:jl] subset: gocheck_obsoletion_candidate synonym: "C-terminal protein geranylgeranylation" NARROW [] synonym: "protein amino acid geranylgeranylation" EXACT [GOC:bf] is_a: GO:0018342 ! protein prenylation [Term] id: GO:0018345 name: protein palmitoylation namespace: biological_process alt_id: GO:0018318 alt_id: GO:0018349 def: "The covalent attachment of a palmitoyl group to a protein." [GOC:jl, PMID:15520806] subset: gocheck_obsoletion_candidate synonym: "protein amino acid palmitoylation" EXACT [GOC:bf] is_a: GO:0006497 ! protein lipidation is_a: GO:0043543 ! protein acylation [Term] id: GO:0018352 name: protein-pyridoxal-5-phosphate linkage namespace: biological_process def: "The formation of a linkage between a protein amino acid and pyridoxal-5-phosphate." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018364 name: peptidyl-glutamine methylation namespace: biological_process def: "The addition of a methyl group to a glutamine residue in a protein." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0006479 ! protein methylation [Term] id: GO:0018377 name: protein myristoylation namespace: biological_process alt_id: GO:0018319 def: "The covalent attachment of a myristoyl group to a protein." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "protein amino acid myristoylation" EXACT [GOC:bf] is_a: GO:0006497 ! protein lipidation is_a: GO:0043543 ! protein acylation [Term] id: GO:0018393 name: internal peptidyl-lysine acetylation namespace: biological_process def: "The addition of an acetyl group to a non-terminal lysine residue in a protein." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0006475 ! internal protein amino acid acetylation is_a: GO:0018394 ! peptidyl-lysine acetylation [Term] id: GO:0018394 name: peptidyl-lysine acetylation namespace: biological_process def: "The acetylation of peptidyl-lysine." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0006473 ! protein acetylation is_a: GO:0018205 ! peptidyl-lysine modification [Term] id: GO:0018395 name: peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine namespace: biological_process def: "The hydroxylation of peptidyl-lysine to peptidyl-5-hydroxy-L-lysine." [RESID:AA0028] subset: gocheck_obsoletion_candidate xref: RESID:AA0028 is_a: GO:0017185 ! peptidyl-lysine hydroxylation [Term] id: GO:0018400 name: peptidyl-proline hydroxylation to 3-hydroxy-L-proline namespace: biological_process def: "The modification of peptidyl-proline to form 3-hydroxy-L-proline; catalyzed by procollagen-proline 3-dioxygenase." [RESID:AA0029] comment: See also the molecular function term 'procollagen-proline 3-dioxygenase activity ; GO:0019797'. subset: gocheck_obsoletion_candidate xref: RESID:AA0029 is_a: GO:0019511 ! peptidyl-proline hydroxylation [Term] id: GO:0018401 name: peptidyl-proline hydroxylation to 4-hydroxy-L-proline namespace: biological_process def: "The modification of peptidyl-proline to form 4-hydroxy-L-proline; catalyzed by procollagen-proline,2-oxoglutarate-4-dioxygenase." [RESID:AA0030] comment: See also the molecular function term 'procollagen-proline 4-dioxygenase activity ; GO:0004656'. subset: gocheck_obsoletion_candidate xref: RESID:AA0030 is_a: GO:0019511 ! peptidyl-proline hydroxylation [Term] id: GO:0018406 name: protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan namespace: biological_process alt_id: GO:0032004 def: "The glycosylation of a peptidyl-tryptophan residue by the transfer of alpha-mannopyranose from dolichyl-activated mannose to the indole ring." [PMID:7947762, PMID:9450955, RESID:AA0217] subset: gocheck_obsoletion_candidate synonym: "protein amino acid C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan" EXACT [GOC:bf] synonym: "protein amino acid C-linked mannosylation" EXACT [] xref: RESID:AA0217 is_a: GO:0018317 ! protein C-linked glycosylation via tryptophan is_a: GO:0097502 ! mannosylation [Term] id: GO:0018410 name: C-terminal protein amino acid modification namespace: biological_process def: "The alteration of the C-terminal amino acid residue in a protein." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "peptide or protein carboxyl-terminal blocking" RELATED [] synonym: "peptide/protein carboxyl-terminal blocking" RELATED [] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0018414 name: nickel incorporation into metallo-sulfur cluster namespace: biological_process def: "The incorporation of nickel into a metallo-sulfur cluster." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "nickel incorporation into metallo-sulphur cluster" EXACT [] is_a: GO:0018282 ! metal incorporation into metallo-sulfur cluster [Term] id: GO:0018418 name: nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide namespace: biological_process def: "The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide." [RESID:AA0293] subset: gocheck_obsoletion_candidate synonym: "nickel incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido L-glutamato L-histidino L-serinyl nickel triiron disulphide trioxide" EXACT [] xref: RESID:AA0293 is_a: GO:0018198 ! peptidyl-cysteine modification is_a: GO:0018200 ! peptidyl-glutamic acid modification is_a: GO:0018202 ! peptidyl-histidine modification is_a: GO:0018414 ! nickel incorporation into metallo-sulfur cluster [Term] id: GO:0018427 name: copper incorporation into metallo-sulfur cluster namespace: biological_process def: "The incorporation of copper into a metallo-sulfur cluster." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "copper incorporation into metallo-sulphur cluster" EXACT [] is_a: GO:0018282 ! metal incorporation into metallo-sulfur cluster [Term] id: GO:0018428 name: copper incorporation into copper-sulfur cluster namespace: biological_process def: "The incorporation of copper into a copper-sulfur cluster." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "copper incorporation into copper-sulphur cluster" EXACT [] is_a: GO:0018427 ! copper incorporation into metallo-sulfur cluster [Term] id: GO:0018533 name: peptidyl-cysteine acetylation namespace: biological_process def: "The acetylation of peptidyl-cysteine." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0006473 ! protein acetylation is_a: GO:0018198 ! peptidyl-cysteine modification [Term] id: GO:0019511 name: peptidyl-proline hydroxylation namespace: biological_process alt_id: GO:0006472 def: "The hydroxylation of peptidyl-proline to form peptidyl-hydroxyproline." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0018126 ! protein hydroxylation is_a: GO:0018208 ! peptidyl-proline modification [Term] id: GO:0019918 name: peptidyl-arginine methylation, to symmetrical-dimethyl arginine namespace: biological_process def: "The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N'(omega)-dimethyl-L-arginine." [RESID:AA0067, RESID:AA0069] subset: gocheck_obsoletion_candidate xref: RESID:AA0067 xref: RESID:AA0069 is_a: GO:0035247 ! peptidyl-arginine omega-N-methylation [Term] id: GO:0019919 name: peptidyl-arginine methylation, to asymmetrical-dimethyl arginine namespace: biological_process def: "The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine." [RESID:AA0068, RESID:AA0069] subset: gocheck_obsoletion_candidate synonym: "peptidyl-arginine methylation, to unsymmetrical-dimethyl arginine" EXACT [] xref: RESID:AA0068 xref: RESID:AA0069 is_a: GO:0035247 ! peptidyl-arginine omega-N-methylation [Term] id: GO:0022898 name: regulation of transmembrane transporter activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transmembrane transporter activity." [GOC:dph, GOC:mtg_cardio, GOC:mtg_transport] subset: gocheck_obsoletion_candidate is_a: GO:0032409 ! regulation of transporter activity [Term] id: GO:0030047 name: actin modification namespace: biological_process alt_id: GO:0007013 def: "Covalent modification of an actin molecule." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0030919 name: peptidyl-serine O-acetylation namespace: biological_process def: "The acetylation of peptidyl-serine to form peptidyl-O-acetyl-L-serine." [PMID:489587, PMID:7309355, RESID:AA0364] subset: gocheck_obsoletion_candidate xref: RESID:AA0364 is_a: GO:0018209 ! peptidyl-serine modification is_a: GO:0030920 ! peptidyl-serine acetylation [Term] id: GO:0030920 name: peptidyl-serine acetylation namespace: biological_process def: "The acetylation of peptidyl-serine." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0006473 ! protein acetylation [Term] id: GO:0030961 name: peptidyl-arginine hydroxylation namespace: biological_process def: "The hydroxylation of peptidyl-arginine to form peptidyl-hydroxyarginine." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0018195 ! peptidyl-arginine modification [Term] id: GO:0031281 name: positive regulation of cyclase activity namespace: biological_process def: "Any process that activates or increases the activity of a cyclase." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "activation of cyclase activity" NARROW [] synonym: "stimulation of cyclase activity" NARROW [] synonym: "up regulation of cyclase activity" EXACT [] synonym: "up-regulation of cyclase activity" EXACT [] synonym: "upregulation of cyclase activity" EXACT [] is_a: GO:0043085 ! positive regulation of catalytic activity [Term] id: GO:0031282 name: regulation of guanylate cyclase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of guanylate cyclase activity." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0050790 ! regulation of catalytic activity [Term] id: GO:0031283 name: negative regulation of guanylate cyclase activity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of guanylate cyclase activity." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "down regulation of guanylate cyclase activity" EXACT [] synonym: "down-regulation of guanylate cyclase activity" EXACT [] synonym: "downregulation of guanylate cyclase activity" EXACT [] synonym: "inhibition of guanylate cyclase activity" NARROW [] is_a: GO:0031282 ! regulation of guanylate cyclase activity is_a: GO:0051350 ! negative regulation of lyase activity [Term] id: GO:0031284 name: positive regulation of guanylate cyclase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of guanylate cyclase activity." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "activation of guanylate cyclase activity" NARROW [] synonym: "stimulation of guanylate cyclase activity" NARROW [] synonym: "up regulation of guanylate cyclase activity" EXACT [] synonym: "up-regulation of guanylate cyclase activity" EXACT [] synonym: "upregulation of guanylate cyclase activity" EXACT [] is_a: GO:0031281 ! positive regulation of cyclase activity is_a: GO:0031282 ! regulation of guanylate cyclase activity is_a: GO:0051349 ! positive regulation of lyase activity [Term] id: GO:0031363 name: N-terminal protein amino acid deamination namespace: biological_process def: "The removal of an amino group from the N-terminal amino acid residue of a protein." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0031365 ! N-terminal protein amino acid modification [Term] id: GO:0031364 name: N-terminal protein amino acid deamination, from side chain namespace: biological_process def: "The removal of an amino group from the side chain of an N-terminal asparagine or glutamine residue of a protein." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0031363 ! N-terminal protein amino acid deamination [Term] id: GO:0031365 name: N-terminal protein amino acid modification namespace: biological_process alt_id: GO:0018409 def: "The alteration of the N-terminal amino acid residue in a protein." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "peptide or protein amino-terminal blocking" RELATED [] synonym: "peptide/protein amino-terminal blocking" RELATED [] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0031400 name: negative regulation of protein modification process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." [GOC:mah, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "down regulation of protein modification" EXACT [] synonym: "down-regulation of protein modification" EXACT [] synonym: "downregulation of protein modification" EXACT [] synonym: "inhibition of protein modification" NARROW [] relationship: negatively_regulates GO:0043412 ! macromolecule modification relationship: regulates GO:0043412 ! macromolecule modification [Term] id: GO:0031401 name: positive regulation of protein modification process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." [GOC:mah, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "activation of protein modification" NARROW [] synonym: "stimulation of protein modification" NARROW [] synonym: "up regulation of protein modification" EXACT [] synonym: "up-regulation of protein modification" EXACT [] synonym: "upregulation of protein modification" EXACT [] relationship: positively_regulates GO:0043412 ! macromolecule modification relationship: regulates GO:0043412 ! macromolecule modification [Term] id: GO:0031584 name: activation of phospholipase D activity namespace: biological_process def: "Any process that initiates the activity of inactive phospholipase D." [GOC:dph, GOC:mah, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0010518 ! positive regulation of phospholipase activity [Term] id: GO:0031585 name: regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel." [GOC:dph, GOC:mah, GOC:signaling] subset: gocheck_obsoletion_candidate synonym: "regulation of inositol-1,4,5-triphosphate receptor activity" EXACT [GOC:signaling] synonym: "regulation of IP3 receptor activity" EXACT [GOC:dph] is_a: GO:1901019 ! regulation of calcium ion transmembrane transporter activity is_a: GO:2001257 ! regulation of cation channel activity [Term] id: GO:0031587 name: positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel." [GOC:dph, GOC:mah, GOC:signaling] subset: gocheck_obsoletion_candidate synonym: "activation of IP3 receptor activity" NARROW [] synonym: "positive regulation of inositol-1,4,5-trisphosphate receptor activity" EXACT [GOC:bf] synonym: "positive regulation of IP3 receptor activity" EXACT [GOC:dph] synonym: "stimulation of IP3 receptor activity" NARROW [] synonym: "up regulation of IP3 receptor activity" EXACT [] synonym: "up-regulation of IP3 receptor activity" EXACT [] synonym: "upregulation of IP3 receptor activity" EXACT [] is_a: GO:0031585 ! regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity is_a: GO:1901021 ! positive regulation of calcium ion transmembrane transporter activity is_a: GO:2001259 ! positive regulation of cation channel activity [Term] id: GO:0031952 name: regulation of protein autophosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of addition of the phosphorylation by a protein of one or more of its own residues." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "regulation of protein amino acid autophosphorylation" EXACT [GOC:bf] is_a: GO:0001932 ! regulation of protein phosphorylation relationship: has_part GO:0045859 ! regulation of protein kinase activity relationship: regulates GO:0046777 ! protein autophosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI [Term] id: GO:0031953 name: negative regulation of protein autophosphorylation namespace: biological_process def: "Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "down regulation of protein amino acid autophosphorylation" EXACT [] synonym: "down-regulation of protein amino acid autophosphorylation" EXACT [] synonym: "downregulation of protein amino acid autophosphorylation" EXACT [] synonym: "inhibition of protein amino acid autophosphorylation" NARROW [] synonym: "negative regulation of protein amino acid autophosphorylation" EXACT [GOC:bf] is_a: GO:0001933 ! negative regulation of protein phosphorylation is_a: GO:0031952 ! regulation of protein autophosphorylation relationship: has_part GO:0006469 ! negative regulation of protein kinase activity relationship: negatively_regulates GO:0046777 ! protein autophosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI [Term] id: GO:0031954 name: positive regulation of protein autophosphorylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "activation of protein amino acid autophosphorylation" NARROW [] synonym: "positive regulation of protein amino acid autophosphorylation" EXACT [GOC:bf] synonym: "stimulation of protein amino acid autophosphorylation" NARROW [] synonym: "up regulation of protein amino acid autophosphorylation" EXACT [] synonym: "up-regulation of protein amino acid autophosphorylation" EXACT [] synonym: "upregulation of protein amino acid autophosphorylation" EXACT [] is_a: GO:0001934 ! positive regulation of protein phosphorylation is_a: GO:0031952 ! regulation of protein autophosphorylation relationship: has_part GO:0045860 ! positive regulation of protein kinase activity relationship: positively_regulates GO:0046777 ! protein autophosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI [Term] id: GO:0032071 name: regulation of endodeoxyribonuclease activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "endodeoxyribonuclease regulator" RELATED [] is_a: GO:0051336 ! regulation of hydrolase activity [Term] id: GO:0032072 name: regulation of restriction endodeoxyribonuclease activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0032071 ! regulation of endodeoxyribonuclease activity [Term] id: GO:0032074 name: negative regulation of nuclease activity namespace: biological_process def: "Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "down regulation of nuclease activity" EXACT [] synonym: "down-regulation of nuclease activity" EXACT [] synonym: "downregulation of nuclease activity" EXACT [] synonym: "inhibition of nuclease activity" NARROW [] synonym: "nuclease inhibitor" RELATED [] is_a: GO:0051346 ! negative regulation of hydrolase activity [Term] id: GO:0032075 name: positive regulation of nuclease activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "activation of nuclease activity" NARROW [] synonym: "nuclease activator" RELATED [] synonym: "stimulation of nuclease activity" NARROW [] synonym: "up regulation of nuclease activity" EXACT [] synonym: "up-regulation of nuclease activity" EXACT [] synonym: "upregulation of nuclease activity" EXACT [] is_a: GO:0051345 ! positive regulation of hydrolase activity [Term] id: GO:0032076 name: negative regulation of deoxyribonuclease activity namespace: biological_process def: "Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "deoxyribonuclease inhibitor" RELATED [] synonym: "DNase inhibitor" RELATED [] synonym: "down regulation of deoxyribonuclease activity" EXACT [] synonym: "down-regulation of deoxyribonuclease activity" EXACT [] synonym: "downregulation of deoxyribonuclease activity" EXACT [] synonym: "inhibition of deoxyribonuclease activity" NARROW [] is_a: GO:0032074 ! negative regulation of nuclease activity [Term] id: GO:0032077 name: positive regulation of deoxyribonuclease activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "activation of deoxyribonuclease activity" NARROW [] synonym: "deoxyribonuclease activator" RELATED [] synonym: "DNase activator" RELATED [] synonym: "stimulation of deoxyribonuclease activity" NARROW [] synonym: "up regulation of deoxyribonuclease activity" EXACT [] synonym: "up-regulation of deoxyribonuclease activity" EXACT [] synonym: "upregulation of deoxyribonuclease activity" EXACT [] is_a: GO:0032075 ! positive regulation of nuclease activity [Term] id: GO:0032078 name: negative regulation of endodeoxyribonuclease activity namespace: biological_process def: "Any process that stops or reduces the rate of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "down regulation of endodeoxyribonuclease activity" EXACT [] synonym: "down-regulation of endodeoxyribonuclease activity" EXACT [] synonym: "downregulation of endodeoxyribonuclease activity" EXACT [] synonym: "endodeoxyribonuclease inhibitor" RELATED [] synonym: "inhibition of endodeoxyribonuclease activity" NARROW [] is_a: GO:0032071 ! regulation of endodeoxyribonuclease activity is_a: GO:0032076 ! negative regulation of deoxyribonuclease activity [Term] id: GO:0032079 name: positive regulation of endodeoxyribonuclease activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "activation of endodeoxyribonuclease activity" NARROW [] synonym: "endodeoxyribonuclease activator" RELATED [] synonym: "stimulation of endodeoxyribonuclease activity" NARROW [] synonym: "up regulation of endodeoxyribonuclease activity" EXACT [] synonym: "up-regulation of endodeoxyribonuclease activity" EXACT [] synonym: "upregulation of endodeoxyribonuclease activity" EXACT [] is_a: GO:0032071 ! regulation of endodeoxyribonuclease activity is_a: GO:0032077 ! positive regulation of deoxyribonuclease activity [Term] id: GO:0032088 name: negative regulation of NF-kappaB transcription factor activity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB." [GOC:dph, GOC:rl, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "inhibition of NF-kappaB transcription factor" EXACT [GOC:dph, GOC:tb] synonym: "NF-kappaB inhibitor" RELATED [] is_a: GO:0043433 ! negative regulation of DNA-binding transcription factor activity [Term] id: GO:0032110 name: regulation of protein histidine kinase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein histidine kinase activity." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0045859 ! regulation of protein kinase activity [Term] id: GO:0032147 name: activation of protein kinase activity namespace: biological_process def: "Any process that initiates the activity of an inactive protein kinase." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "protein kinase activation" RELATED [] is_a: GO:0045860 ! positive regulation of protein kinase activity [Term] id: GO:0032148 name: activation of protein kinase B activity namespace: biological_process def: "Any process that initiates the activity of the inactive enzyme protein kinase B." [GOC:pg] subset: gocheck_obsoletion_candidate synonym: "protein kinase B activation" EXACT [] is_a: GO:0032147 ! activation of protein kinase activity [Term] id: GO:0032237 name: activation of store-operated calcium channel activity namespace: biological_process def: "A process that initiates the activity of an inactive store-operated calcium channel." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:1901341 ! positive regulation of store-operated calcium channel activity [Term] id: GO:0032409 name: regulation of transporter activity namespace: biological_process def: "Any process that modulates the activity of a transporter." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0065009 ! regulation of molecular function [Term] id: GO:0032410 name: negative regulation of transporter activity namespace: biological_process def: "Any process that stops or reduces the activity of a transporter." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "down regulation of transporter activity" EXACT [] synonym: "down-regulation of transporter activity" EXACT [] synonym: "downregulation of transporter activity" EXACT [] synonym: "inhibition of transporter activity" NARROW [] is_a: GO:0032409 ! regulation of transporter activity [Term] id: GO:0032411 name: positive regulation of transporter activity namespace: biological_process def: "Any process that activates or increases the activity of a transporter." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "activation of transporter activity" NARROW [] synonym: "stimulation of transporter activity" NARROW [] synonym: "up regulation of transporter activity" EXACT [] synonym: "up-regulation of transporter activity" EXACT [] synonym: "upregulation of transporter activity" EXACT [] is_a: GO:0032409 ! regulation of transporter activity is_a: GO:0044093 ! positive regulation of molecular function [Term] id: GO:0032412 name: regulation of monoatomic ion transmembrane transporter activity namespace: biological_process def: "Any process that modulates the activity of an ion transporter." [GOC:mah, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "regulation of ion transmembrane transporter activity" BROAD [] synonym: "regulation of ion transporter activity" EXACT [GOC:tb] is_a: GO:0022898 ! regulation of transmembrane transporter activity [Term] id: GO:0032413 name: negative regulation of ion transmembrane transporter activity namespace: biological_process def: "Any process that stops or reduces the activity of an ion transporter." [GOC:mah, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "down regulation of ion transporter activity" EXACT [] synonym: "down-regulation of ion transporter activity" EXACT [] synonym: "downregulation of ion transporter activity" EXACT [] synonym: "inhibition of ion transporter activity" NARROW [] synonym: "negative regulation of ion transporter activity" EXACT [GOC:tb] is_a: GO:0032410 ! negative regulation of transporter activity is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity [Term] id: GO:0032414 name: positive regulation of ion transmembrane transporter activity namespace: biological_process def: "Any process that activates or increases the activity of an ion transporter." [GOC:mah, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "activation of ion transporter activity" NARROW [] synonym: "positive regulation of ion transporter activity" EXACT [GOC:tb] synonym: "stimulation of ion transporter activity" NARROW [] synonym: "up regulation of ion transporter activity" EXACT [] synonym: "up-regulation of ion transporter activity" EXACT [] synonym: "upregulation of ion transporter activity" EXACT [] is_a: GO:0032411 ! positive regulation of transporter activity is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity [Term] id: GO:0032416 name: negative regulation of sodium:proton antiporter activity namespace: biological_process def: "Any process that stops or reduces the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out)." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "down regulation of sodium:hydrogen antiporter activity" EXACT [] synonym: "down-regulation of sodium:hydrogen antiporter activity" EXACT [] synonym: "downregulation of sodium:hydrogen antiporter activity" EXACT [] synonym: "inhibition of sodium:hydrogen antiporter activity" NARROW [] synonym: "negative regulation of sodium:hydrogen antiporter activity" EXACT [] is_a: GO:2000650 ! negative regulation of sodium ion transmembrane transporter activity [Term] id: GO:0032417 name: positive regulation of sodium:proton antiporter activity namespace: biological_process def: "Any process that activates or increases the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out)." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "activation of sodium:hydrogen antiporter activity" NARROW [] synonym: "positive regulation of sodium:hydrogen antiporter activity" EXACT [] synonym: "stimulation of sodium:hydrogen antiporter activity" NARROW [] synonym: "up regulation of sodium:hydrogen antiporter activity" EXACT [] synonym: "up-regulation of sodium:hydrogen antiporter activity" EXACT [] synonym: "upregulation of sodium:hydrogen antiporter activity" EXACT [] is_a: GO:2000651 ! positive regulation of sodium ion transmembrane transporter activity [Term] id: GO:0032429 name: regulation of phospholipase A2 activity namespace: biological_process def: "Any process that modulates the activity of the enzyme phospholipase A2." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0010517 ! regulation of phospholipase activity [Term] id: GO:0032430 name: positive regulation of phospholipase A2 activity namespace: biological_process def: "Any process that activates or increases the activity of the enzyme phospholipase A2." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "activation of phospholipase A2 activity" NARROW [] synonym: "stimulation of phospholipase A2 activity" NARROW [] synonym: "up regulation of phospholipase A2 activity" EXACT [] synonym: "up-regulation of phospholipase A2 activity" EXACT [] synonym: "upregulation of phospholipase A2 activity" EXACT [] is_a: GO:0010518 ! positive regulation of phospholipase activity is_a: GO:0032429 ! regulation of phospholipase A2 activity [Term] id: GO:0032431 name: activation of phospholipase A2 activity namespace: biological_process def: "Any process that initiates the activity of the inactive enzyme phospholipase A2." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "phospholipase A2 activation" EXACT [] is_a: GO:0032430 ! positive regulation of phospholipase A2 activity [Term] id: GO:0032769 name: negative regulation of monooxygenase activity namespace: biological_process def: "Any process that stops or reduces the activity of a monooxygenase." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "down regulation of monooxygenase activity" EXACT [] synonym: "down-regulation of monooxygenase activity" EXACT [] synonym: "downregulation of monooxygenase activity" EXACT [] synonym: "inhibition of monooxygenase activity" NARROW [] is_a: GO:0051354 ! negative regulation of oxidoreductase activity [Term] id: GO:0032770 name: positive regulation of monooxygenase activity namespace: biological_process def: "Any process that activates or increases the activity of a monooxygenase." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "activation of monooxygenase activity" NARROW [] synonym: "stimulation of monooxygenase activity" NARROW [] synonym: "up regulation of monooxygenase activity" EXACT [] synonym: "up-regulation of monooxygenase activity" EXACT [] synonym: "upregulation of monooxygenase activity" EXACT [] is_a: GO:0051353 ! positive regulation of oxidoreductase activity [Term] id: GO:0032773 name: positive regulation of tyrosinase activity namespace: biological_process def: "Any process that activates or increases the activity of a tyrosinase enzyme monophenol oxygenase." [GOC:dph, GOC:mah, GOC:tb, PMID:2494997] subset: gocheck_obsoletion_candidate synonym: "activation of monophenol oxygenase activity" NARROW [] synonym: "positive regulation of monophenol monooxygenase activity" RELATED [] synonym: "positive regulation of monophenol oxygenase activity" EXACT [GOC:dph, GOC:tb, PMID:2494997] synonym: "stimulation of monophenol oxygenase activity" NARROW [] synonym: "up regulation of monophenol oxygenase activity" EXACT [] synonym: "up-regulation of monophenol oxygenase activity" EXACT [] synonym: "upregulation of monophenol oxygenase activity" EXACT [] is_a: GO:0032770 ! positive regulation of monooxygenase activity property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/21024" xsd:anyURI [Term] id: GO:0032780 name: negative regulation of ATP-dependent activity namespace: biological_process def: "Any process that stops or reduces the rate of an ATP-dependent activity." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "down regulation of ATPase activity" EXACT [] synonym: "down-regulation of ATPase activity" EXACT [] synonym: "downregulation of ATPase activity" EXACT [] synonym: "inhibition of ATPase activity" NARROW [] synonym: "negative regulation of adenosinetriphosphatase activity" EXACT [] synonym: "negative regulation of ATPase activity" EXACT [] is_a: GO:0043462 ! regulation of ATP-dependent activity property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22371" xsd:anyURI [Term] id: GO:0032781 name: positive regulation of ATP-dependent activity namespace: biological_process def: "Any process that activates or increases the rate of an ATP-dependent activity." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "activation of ATPase activity" NARROW [] synonym: "positive regulation of adenosinetriphosphatase activity" EXACT [] synonym: "positive regulation of ATPase activity" EXACT [] synonym: "stimulation of ATPase activity" NARROW [] synonym: "up regulation of ATPase activity" EXACT [] synonym: "up-regulation of ATPase activity" EXACT [] synonym: "upregulation of ATPase activity" EXACT [] is_a: GO:0043462 ! regulation of ATP-dependent activity is_a: GO:0044093 ! positive regulation of molecular function property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22371" xsd:anyURI [Term] id: GO:0032792 name: negative regulation of CREB transcription factor activity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor CREB." [GOC:dph, GOC:ecd, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "CREB inhibitor" RELATED [] synonym: "inhibition of CREB transcription factor" EXACT [GOC:dph, GOC:tb] is_a: GO:0043433 ! negative regulation of DNA-binding transcription factor activity [Term] id: GO:0032793 name: positive regulation of CREB transcription factor activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB." [GOC:dph, GOC:ecd, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "activation of CREB" EXACT [] synonym: "activation of CREB transcription factor" EXACT [GOC:dph, GOC:tb] synonym: "CREB activator" RELATED [] is_a: GO:0051091 ! positive regulation of DNA-binding transcription factor activity [Term] id: GO:0033132 name: negative regulation of glucokinase activity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "down regulation of glucokinase activity" EXACT [] synonym: "down-regulation of glucokinase activity" EXACT [] synonym: "downregulation of glucokinase activity" EXACT [] synonym: "glucokinase inhibitor" NARROW [] synonym: "inhibition of glucokinase activity" NARROW [] is_a: GO:1903300 ! negative regulation of hexokinase activity [Term] id: GO:0033133 name: positive regulation of glucokinase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "glucokinase activator" NARROW [] synonym: "stimulation of glucokinase activity" NARROW [] synonym: "up regulation of glucokinase activity" EXACT [] synonym: "up-regulation of glucokinase activity" EXACT [] synonym: "upregulation of glucokinase activity" EXACT [] is_a: GO:1903301 ! positive regulation of hexokinase activity [Term] id: GO:0033135 name: regulation of peptidyl-serine phosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0001932 ! regulation of protein phosphorylation relationship: regulates GO:0018105 ! peptidyl-serine phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI [Term] id: GO:0033137 name: negative regulation of peptidyl-serine phosphorylation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-serine." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0001933 ! negative regulation of protein phosphorylation is_a: GO:0033135 ! regulation of peptidyl-serine phosphorylation relationship: negatively_regulates GO:0018105 ! peptidyl-serine phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI [Term] id: GO:0033138 name: positive regulation of peptidyl-serine phosphorylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0001934 ! positive regulation of protein phosphorylation is_a: GO:0033135 ! regulation of peptidyl-serine phosphorylation relationship: positively_regulates GO:0018105 ! peptidyl-serine phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI [Term] id: GO:0033139 name: regulation of peptidyl-serine phosphorylation of STAT protein namespace: biological_process alt_id: GO:1903261 def: "Any process that modulates the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "regulation of serine phosphorylation of STAT3 protein" NARROW [] is_a: GO:0033135 ! regulation of peptidyl-serine phosphorylation relationship: regulates GO:0042501 ! serine phosphorylation of STAT protein created_by: mr creation_date: 2014-08-06T21:22:57Z [Term] id: GO:0033140 name: negative regulation of peptidyl-serine phosphorylation of STAT protein namespace: biological_process alt_id: GO:1903262 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "down regulation of serine phosphorylation of STAT3 protein" NARROW [GOC:TermGenie] synonym: "down-regulation of serine phosphorylation of STAT3 protein" NARROW [GOC:TermGenie] synonym: "downregulation of serine phosphorylation of STAT3 protein" NARROW [GOC:TermGenie] synonym: "inhibition of serine phosphorylation of STAT3 protein" NARROW [GOC:TermGenie] synonym: "negative regulation of serine phosphorylation of STAT3 protein" NARROW [] is_a: GO:0033137 ! negative regulation of peptidyl-serine phosphorylation is_a: GO:0033139 ! regulation of peptidyl-serine phosphorylation of STAT protein relationship: negatively_regulates GO:0042501 ! serine phosphorylation of STAT protein property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI [Term] id: GO:0033141 name: positive regulation of peptidyl-serine phosphorylation of STAT protein namespace: biological_process alt_id: GO:1903263 def: "Any process that activates or increases the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "activation of serine phosphorylation of STAT3 protein" NARROW [GOC:TermGenie] synonym: "positive regulation of serine phosphorylation of STAT3 protein" NARROW [] synonym: "up regulation of serine phosphorylation of STAT3 protein" NARROW [GOC:TermGenie] synonym: "up-regulation of serine phosphorylation of STAT3 protein" NARROW [GOC:TermGenie] synonym: "upregulation of serine phosphorylation of STAT3 protein" NARROW [GOC:TermGenie] is_a: GO:0033138 ! positive regulation of peptidyl-serine phosphorylation is_a: GO:0033139 ! regulation of peptidyl-serine phosphorylation of STAT protein relationship: positively_regulates GO:0042501 ! serine phosphorylation of STAT protein property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI [Term] id: GO:0033252 name: regulation of beta-lactamase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of beta-lactamase activity, the hydrolysis of a beta-lactam to yield a substituted beta-amino acid." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0051336 ! regulation of hydrolase activity [Term] id: GO:0033673 name: negative regulation of kinase activity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "down regulation of kinase activity" EXACT [] synonym: "down-regulation of kinase activity" EXACT [] synonym: "downregulation of kinase activity" EXACT [] synonym: "inhibition of kinase activity" NARROW [] synonym: "kinase inhibitor" NARROW [] is_a: GO:0042326 ! negative regulation of phosphorylation is_a: GO:0043549 ! regulation of kinase activity is_a: GO:0051348 ! negative regulation of transferase activity [Term] id: GO:0033674 name: positive regulation of kinase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "kinase activator" NARROW [] synonym: "stimulation of kinase activity" NARROW [] synonym: "up regulation of kinase activity" EXACT [] synonym: "up-regulation of kinase activity" EXACT [] synonym: "upregulation of kinase activity" EXACT [] is_a: GO:0043549 ! regulation of kinase activity is_a: GO:0051347 ! positive regulation of transferase activity relationship: positively_regulates GO:0016310 ! phosphorylation [Term] id: GO:0033860 name: regulation of NAD(P)H oxidase activity namespace: biological_process def: "Any process that modulates the activity of the enzyme NAD(P)H oxidase." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0051341 ! regulation of oxidoreductase activity [Term] id: GO:0033861 name: negative regulation of NAD(P)H oxidase activity namespace: biological_process def: "Any process that stops or reduces the activity of the enzyme NAD(P)H oxidase." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "down regulation of NAD(P)H oxidase activity" EXACT [] synonym: "down-regulation of NAD(P)H oxidase activity" EXACT [] synonym: "downregulation of NAD(P)H oxidase activity" EXACT [] synonym: "inhibition of NAD(P)H oxidase activity" NARROW [] is_a: GO:0033860 ! regulation of NAD(P)H oxidase activity is_a: GO:0051354 ! negative regulation of oxidoreductase activity [Term] id: GO:0033864 name: positive regulation of NAD(P)H oxidase activity namespace: biological_process def: "Any process that activates or increases the activity of the enzyme NAD(P)H oxidase." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "activation of NAD(P)H oxidase activity" NARROW [] synonym: "stimulation of NAD(P)H oxidase activity" NARROW [] synonym: "up regulation of NAD(P)H oxidase activity" EXACT [] synonym: "up-regulation of NAD(P)H oxidase activity" EXACT [] synonym: "upregulation of NAD(P)H oxidase activity" EXACT [] is_a: GO:0033860 ! regulation of NAD(P)H oxidase activity is_a: GO:0051353 ! positive regulation of oxidoreductase activity [Term] id: GO:0034199 name: activation of protein kinase A activity namespace: biological_process def: "Any process that initiates the activity of the inactive enzyme protein kinase A." [GOC:pde] subset: gocheck_obsoletion_candidate synonym: "protein kinase A activation" EXACT [] xref: Reactome:R-HSA-163615 "PKA activation" is_a: GO:0032147 ! activation of protein kinase activity [Term] id: GO:0034260 name: negative regulation of GTPase activity namespace: biological_process alt_id: GO:0034259 alt_id: GO:0034261 alt_id: GO:1902264 alt_id: GO:1902881 def: "Any process that stops or reduces the rate of GTP hydrolysis by a GTPase." [GO_REF:0000058, GOC:mah, GOC:rb, GOC:TermGenie, PMID:16143306, PMID:24335649] comment: An example of this is P2xA in Dictyostelium (UniProt symbol Q86JM7) in PMID:24335649. subset: gocheck_obsoletion_candidate synonym: "down regulation of GTPase activity" EXACT [] synonym: "down regulation of Rab GTPase activity" NARROW [GOC:pf] synonym: "down regulation of Ras GTPase activity" NARROW [] synonym: "down regulation of regulation of Ran GTPase activity" NARROW [GOC:TermGenie] synonym: "down regulation of Rho GTPase activity" NARROW [] synonym: "down-regulation of GTPase activity" EXACT [] synonym: "down-regulation of Rab GTPase activity" NARROW [GOC:pf] synonym: "down-regulation of Ras GTPase activity" NARROW [] synonym: "down-regulation of regulation of Ran GTPase activity" NARROW [GOC:TermGenie] synonym: "down-regulation of Rho GTPase activity" NARROW [] synonym: "downregulation of GTPase activity" EXACT [] synonym: "downregulation of Rab GTPase activity" NARROW [GOC:pf] synonym: "downregulation of Ras GTPase activity" NARROW [] synonym: "downregulation of regulation of Ran GTPase activity" NARROW [GOC:TermGenie] synonym: "downregulation of Rho GTPase activity" NARROW [] synonym: "inhibition of GTPase activity" NARROW [] synonym: "inhibition of Rab GTPase activity" NARROW [GOC:pf] synonym: "inhibition of Ras GTPase activity" NARROW [] synonym: "inhibition of regulation of Ran GTPase activity" NARROW [GOC:TermGenie] synonym: "inhibition of Rho GTPase activity" NARROW [] synonym: "negative regulation of guanosinetriphosphatase activity" EXACT [] synonym: "negative regulation of Rab GTPase activity" NARROW [] synonym: "negative regulation of Ran GTPase activity" NARROW [] synonym: "negative regulation of Ras GTPase activity" NARROW [] synonym: "negative regulation of Rho GTPase activity" NARROW [] is_a: GO:0051346 ! negative regulation of hydrolase activity [Term] id: GO:0034421 name: post-translational protein acetylation namespace: biological_process def: "The addition of an acetyl group to one or more amino acids in a protein, occurring after the protein has been completely translated and released from the ribosome." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "post-translational protein amino acid acetylation" EXACT [GOC:bf] synonym: "posttranslational protein amino acid acetylation" EXACT [] is_a: GO:0006473 ! protein acetylation [Term] id: GO:0034983 name: peptidyl-lysine deacetylation namespace: biological_process def: "The removal of an acetyl group from an acetylated lysine residue in a peptide or protein." [GOC:BHF, GOC:mah] subset: gocheck_obsoletion_candidate synonym: "protein lysine acetylation" RELATED [] is_a: GO:0006476 ! protein deacetylation is_a: GO:0018205 ! peptidyl-lysine modification [Term] id: GO:0035229 name: positive regulation of glutamate-cysteine ligase activity namespace: biological_process def: "Any process that activates or increases the activity of glutamate-cysteine ligase, typically by lowering its sensitivity to inhibition by glutathione and by increasing its affinity for glutamate." [PMID:12954617] subset: gocheck_obsoletion_candidate synonym: "activation of glutamate-cysteine ligase activity" NARROW [] synonym: "stimulation of glutamate-cysteine ligase activity" NARROW [] synonym: "up regulation of glutamate-cysteine ligase activity" EXACT [] synonym: "up-regulation of glutamate-cysteine ligase activity" EXACT [] synonym: "upregulation of glutamate-cysteine ligase activity" EXACT [] is_a: GO:0051351 ! positive regulation of ligase activity [Term] id: GO:0035246 name: peptidyl-arginine N-methylation namespace: biological_process def: "The addition of a methyl group onto a nitrogen atom of an arginine residue in a protein." [GOC:bf] subset: gocheck_obsoletion_candidate is_a: GO:0018216 ! peptidyl-arginine methylation [Term] id: GO:0035247 name: peptidyl-arginine omega-N-methylation namespace: biological_process def: "The addition of a methyl group onto a terminal nitrogen (omega nitrogen) atom of an arginine residue in a protein." [PMID:14705965, RESID:AA0067, RESID:AA0068, RESID:AA0069] subset: gocheck_obsoletion_candidate xref: RESID:AA0067 xref: RESID:AA0068 xref: RESID:AA0069 is_a: GO:0035246 ! peptidyl-arginine N-methylation [Term] id: GO:0035335 name: peptidyl-tyrosine dephosphorylation namespace: biological_process def: "The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine." [GOC:bf] subset: gocheck_obsoletion_candidate is_a: GO:0006470 ! protein dephosphorylation created_by: bf creation_date: 2010-03-01T01:09:14Z [Term] id: GO:0035568 name: N-terminal peptidyl-proline methylation namespace: biological_process def: "The methylation of the N-terminal proline of proteins." [PMID:20668449, RESID:AA0419] subset: gocheck_obsoletion_candidate xref: RESID:AA0419 is_a: GO:0006480 ! N-terminal protein amino acid methylation is_a: GO:0018208 ! peptidyl-proline modification created_by: bf creation_date: 2010-08-06T01:52:43Z [Term] id: GO:0035570 name: N-terminal peptidyl-serine methylation namespace: biological_process def: "The methylation of the N-terminal serine of proteins." [PMID:20668449] subset: gocheck_obsoletion_candidate is_a: GO:0006480 ! N-terminal protein amino acid methylation is_a: GO:0018209 ! peptidyl-serine modification created_by: bf creation_date: 2010-08-06T01:58:11Z [Term] id: GO:0035572 name: N-terminal peptidyl-serine dimethylation namespace: biological_process def: "The dimethylation of the N-terminal serine of proteins to form the derivative N,N-dimethylserine." [PMID:20668449] subset: gocheck_obsoletion_candidate is_a: GO:0035570 ! N-terminal peptidyl-serine methylation created_by: bf creation_date: 2010-08-06T02:00:17Z [Term] id: GO:0035573 name: N-terminal peptidyl-serine trimethylation namespace: biological_process def: "The trimethylation of the N-terminal serine of proteins to form the derivative N,N,N-trimethylserine." [PMID:20668449] subset: gocheck_obsoletion_candidate is_a: GO:0035570 ! N-terminal peptidyl-serine methylation created_by: bf creation_date: 2010-08-06T02:00:42Z [Term] id: GO:0035601 name: protein deacylation namespace: biological_process def: "The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a protein amino acid." [GOC:se, PMID:12080046] subset: gocheck_obsoletion_candidate synonym: "protein amino acid deacylation" EXACT [GOC:se] is_a: GO:0043412 ! macromolecule modification created_by: bf creation_date: 2010-11-15T11:06:15Z [Term] id: GO:0035606 name: peptidyl-cysteine S-trans-nitrosylation namespace: biological_process def: "Transfer of a nitric oxide (NO) group from one cysteine residue to another." [PMID:19854201, PMID:20972425, PMID:20972426] subset: gocheck_obsoletion_candidate synonym: "cysteine to cysteine nitrosylation" EXACT [PMID:20972426] synonym: "cysteine-to-cysteine transnitrosylation" EXACT [PMID:20972426] synonym: "protein-to-protein transnitrosylation" BROAD [PMID:20972426] synonym: "S-transnitrosylation" EXACT [PMID:20972426] is_a: GO:0018119 ! peptidyl-cysteine S-nitrosylation created_by: bf creation_date: 2010-11-16T09:54:46Z [Term] id: GO:0035608 name: protein deglutamylation namespace: biological_process def: "The removal of a glutamate residue from a protein. Glutamate residues in proteins can be gene-encoded, or added as side chains during the protein modification process of polyglutamylation." [GOC:sp, PMID:21074048] subset: gocheck_obsoletion_candidate synonym: "protein amino acid deglutamylation" EXACT [GOC:bf] is_a: GO:0018200 ! peptidyl-glutamic acid modification created_by: bf creation_date: 2010-11-18T01:04:38Z [Term] id: GO:0035609 name: C-terminal protein deglutamylation namespace: biological_process def: "The removal of a C-terminal, gene-encoded glutamate residue from a protein." [GOC:sp, PMID:21074048] subset: gocheck_obsoletion_candidate synonym: "protein primary sequence deglutamylation" EXACT [PMID:21074048] is_a: GO:0018410 ! C-terminal protein amino acid modification is_a: GO:0035608 ! protein deglutamylation created_by: bf creation_date: 2010-11-18T01:06:00Z [Term] id: GO:0035610 name: protein side chain deglutamylation namespace: biological_process def: "The removal of a glutamate residue from the side chain of a protein. Glutamate side chains are added to glutamic acid residues within the primary protein sequence during polyglutamylation." [GOC:sp, PMID:21074048] subset: gocheck_obsoletion_candidate synonym: "removal of posttranslational polyglutamylation" EXACT [PMID:21074048] synonym: "shortening of glutamate side chain" RELATED [PMID:21074048] is_a: GO:0035608 ! protein deglutamylation created_by: bf creation_date: 2010-11-18T01:09:03Z [Term] id: GO:0035611 name: protein branching point deglutamylation namespace: biological_process def: "The removal of a branching point glutamate residue. A branching point glutamate connects a glutamate side chain to a gene-encoded glutamate residue." [GOC:sp, PMID:21074048] subset: gocheck_obsoletion_candidate is_a: GO:0035608 ! protein deglutamylation created_by: bf creation_date: 2010-11-18T01:11:21Z [Term] id: GO:0035970 name: peptidyl-threonine dephosphorylation namespace: biological_process def: "The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine." [GOC:bf] subset: gocheck_obsoletion_candidate is_a: GO:0006470 ! protein dephosphorylation created_by: bf creation_date: 2011-08-08T02:57:11Z [Term] id: GO:0035971 name: peptidyl-histidine dephosphorylation namespace: biological_process def: "The removal of phosphoric residues from peptidyl-O-phospho-L-histidine to form peptidyl-histidine." [GOC:BHF, GOC:vk, PMID:12383260] subset: gocheck_obsoletion_candidate is_a: GO:0006470 ! protein dephosphorylation created_by: bf creation_date: 2011-08-08T03:26:02Z [Term] id: GO:0035977 name: protein deglycosylation involved in glycoprotein catabolic process namespace: biological_process def: "The removal of sugar residues from a glycosylated protein that contributes to the breakdown of a glycoprotein." [GOC:bf, GOC:vw] subset: gocheck_obsoletion_candidate is_a: GO:0006517 ! protein deglycosylation created_by: bf creation_date: 2011-08-18T10:31:23Z [Term] id: GO:0036046 name: protein demalonylation namespace: biological_process def: "The removal of a malonyl group (CO-CH2-CO), from an amino acid residue within a protein or peptide." [GOC:sp, PMID:22076378] subset: gocheck_obsoletion_candidate is_a: GO:0035601 ! protein deacylation created_by: bf creation_date: 2011-12-12T09:38:26Z [Term] id: GO:0036047 name: peptidyl-lysine demalonylation namespace: biological_process def: "The process of removing a malonyl group (CO-CH2-CO) from an malonylated lysine residue in a peptide or protein." [GOC:sp, PMID:22076378] subset: gocheck_obsoletion_candidate is_a: GO:0018205 ! peptidyl-lysine modification is_a: GO:0036046 ! protein demalonylation created_by: bf creation_date: 2011-12-12T09:39:17Z [Term] id: GO:0036048 name: protein desuccinylation namespace: biological_process def: "The removal of a succinyl group (CO-CH2-CH2-CO) from a residue in a peptide or protein." [GOC:sp, PMID:22076378] subset: gocheck_obsoletion_candidate is_a: GO:0035601 ! protein deacylation created_by: bf creation_date: 2011-12-12T09:42:35Z [Term] id: GO:0036049 name: peptidyl-lysine desuccinylation namespace: biological_process def: "The removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue in a peptide or protein." [GOC:sp, PMID:22076378] subset: gocheck_obsoletion_candidate is_a: GO:0018205 ! peptidyl-lysine modification is_a: GO:0036048 ! protein desuccinylation created_by: bf creation_date: 2011-12-12T09:44:54Z [Term] id: GO:0036289 name: peptidyl-serine autophosphorylation namespace: biological_process def: "The phosphorylation by a protein of one or more of its own serine amino acid residues, or a serine residue on an identical protein." [GOC:pm] subset: gocheck_obsoletion_candidate synonym: "serine autophosphorylation" EXACT [GOC:bf] is_a: GO:0018105 ! peptidyl-serine phosphorylation is_a: GO:0046777 ! protein autophosphorylation created_by: bf creation_date: 2012-07-18T10:24:32Z [Term] id: GO:0036290 name: protein trans-autophosphorylation namespace: biological_process def: "The phosphorylation by a protein of a residue on an identical protein. For example, phosphorylation by the other kinase within a homodimer." [GOC:jsg, PMID:20516151] subset: gocheck_obsoletion_candidate synonym: "trans-autophosphorylation" EXACT [GOC:jsg] is_a: GO:0046777 ! protein autophosphorylation created_by: bf creation_date: 2012-07-18T10:27:06Z [Term] id: GO:0036492 name: eiF2alpha phosphorylation in response to endoplasmic reticulum stress namespace: biological_process def: "The addition of a phosphate group on to the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress." [GOC:bf, GOC:PARL, PMID:14676213, PMID:16835242] subset: gocheck_obsoletion_candidate synonym: "eiF2alpha phosphorylation in response to ER stress" EXACT [GOC:bf] synonym: "regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:bf] is_a: GO:0010998 ! regulation of translational initiation by eIF2 alpha phosphorylation created_by: bf creation_date: 2015-02-05T09:53:21Z [Term] id: GO:0036496 name: regulation of translational initiation by eIF2 alpha dephosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the dephosphorylation of eIF2 alpha." [GOC:bf, GOC:PARL] subset: gocheck_obsoletion_candidate is_a: GO:0006470 ! protein dephosphorylation created_by: bf creation_date: 2015-02-05T10:21:31Z [Term] id: GO:0036497 name: eIF2alpha dephosphorylation in response to endoplasmic reticulum stress namespace: biological_process def: "The removal of a phosphate group from the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress." [GOC:bf, GOC:PARL, PMID:16835242] subset: gocheck_obsoletion_candidate synonym: "eIF2alpha dephosphorylation in response to ER stress" EXACT [GOC:bf] synonym: "regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:bf] is_a: GO:0036496 ! regulation of translational initiation by eIF2 alpha dephosphorylation created_by: bf creation_date: 2015-02-05T10:24:18Z [Term] id: GO:0036507 name: protein demannosylation namespace: biological_process def: "The removal of one or more mannose residues from a mannosylated protein." [GOC:bf, GOC:PARL, PMID:25092655] comment: Consider also annotating to the term 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'. subset: gocheck_obsoletion_candidate synonym: "protein de-mannosylation" EXACT [GOC:bf] is_a: GO:0006517 ! protein deglycosylation created_by: bf creation_date: 2015-06-11T13:57:01Z [Term] id: GO:0036508 name: protein alpha-1,2-demannosylation namespace: biological_process def: "The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein." [GOC:bf, GOC:PARL, PMID:21062743, PMID:25092655] comment: Consider also annotating to 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'. subset: gocheck_obsoletion_candidate synonym: "glycoprotein mannose trimming" RELATED [GOC:bf] synonym: "mannose trimming" BROAD [PMID:21062743] is_a: GO:0036507 ! protein demannosylation created_by: bf creation_date: 2015-06-11T13:58:50Z [Term] id: GO:0036510 name: trimming of terminal mannose on C branch namespace: biological_process def: "The removal of an alpha-1,2-linked mannose from the C-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum." [GOC:bf, GOC:PARL, PMID:20065073] comment: Consider also annotating to 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'. subset: gocheck_obsoletion_candidate synonym: "conversion of (Man)9(GlcNAc)2 to (Man)8C(GlcNAc)2" RELATED [PMID:20065073] synonym: "conversion of M9 to M8C" RELATED [GOC:bf] synonym: "glycoprotein mannose trimming on C branch" EXACT [GOC:bf] is_a: GO:0036508 ! protein alpha-1,2-demannosylation created_by: bf creation_date: 2015-06-11T14:10:52Z [Term] id: GO:0036525 name: protein deglycation namespace: biological_process def: "The removal of a sugar or dicarbonyl from a glycated protein." [GOC:bf, GOC:PARL, PMID:14568004, PMID:25416785] comment: Glycation is a non enzymatic covalent addition of a sugar or dicarbonyl (methylglyoxal, glyoxal) to a protein. Deglycation repairs the glycated amino acids. subset: gocheck_obsoletion_candidate synonym: "glycated protein repair" RELATED [PMID:25416785] is_a: GO:0043412 ! macromolecule modification created_by: bf creation_date: 2016-08-04T10:28:54Z [Term] id: GO:0036526 name: peptidyl-cysteine deglycation namespace: biological_process def: "The removal of a sugar or dicarbonyl from a cysteine residue of a glycated protein." [GOC:bf, GOC:PARL, PMID:14568004, PMID:25416785] subset: gocheck_obsoletion_candidate synonym: "deglycation of N-acetylcysteine" RELATED [PMID:25416785] is_a: GO:0018198 ! peptidyl-cysteine modification is_a: GO:0036525 ! protein deglycation created_by: bf creation_date: 2016-08-04T10:35:25Z [Term] id: GO:0036527 name: peptidyl-arginine deglycation namespace: biological_process def: "The removal of a sugar or dicarbonyl from an arginine residue of a glycated protein." [GOC:bf, GOC:PARL, PMID:14568004, PMID:25416785] subset: gocheck_obsoletion_candidate synonym: "deglycation of N-acetylarginine" RELATED [PMID:25416785] is_a: GO:0018195 ! peptidyl-arginine modification is_a: GO:0036525 ! protein deglycation created_by: bf creation_date: 2016-08-04T10:36:30Z [Term] id: GO:0036528 name: peptidyl-lysine deglycation namespace: biological_process def: "The removal of a sugar or dicarbonyl from a lysine residue of a glycated protein." [GOC:bf, GOC:PARL, PMID:14568004, PMID:25416785] subset: gocheck_obsoletion_candidate synonym: "deglycation of N-acetyllysine" RELATED [PMID:25416785] is_a: GO:0018205 ! peptidyl-lysine modification is_a: GO:0036525 ! protein deglycation created_by: bf creation_date: 2016-08-04T10:37:12Z [Term] id: GO:0036529 name: protein deglycation, glyoxal removal namespace: biological_process def: "The removal of glyoxal from a glycated protein, to form glycolate and a deglycated protein." [GOC:bf, GOC:PARL, PMID:25416785] subset: gocheck_obsoletion_candidate synonym: "protein deglycation of glyoxal-glycated protein" RELATED [PMID:25416785] is_a: GO:0036525 ! protein deglycation created_by: bf creation_date: 2016-08-04T10:41:25Z [Term] id: GO:0036530 name: protein deglycation, methylglyoxal removal namespace: biological_process def: "The removal of methylglyoxal from a glycated protein, to form lactate and a deglycated protein." [GOC:bf, GOC:PARL, PMID:25416785] subset: gocheck_obsoletion_candidate synonym: "protein deglycation of methylglyoxal-glycated protein" RELATED [PMID:25416785] is_a: GO:0036525 ! protein deglycation created_by: bf creation_date: 2016-08-04T10:42:26Z [Term] id: GO:0038041 name: cross-receptor inhibition within G protein-coupled receptor heterodimer namespace: biological_process def: "Inhibition of one protomer of a G protein-coupled receptor (GPCR) heterodimer by the associated subunit. For example, agonist activation of one cytokine receptor can prevent activation of its associated cytokine receptor subunit." [GOC:al, GOC:bf, PMID:15979374] subset: gocheck_obsoletion_candidate synonym: "cross-receptor inhibition within G-protein coupled receptor heterodimer" EXACT [] is_a: GO:2000272 ! negative regulation of signaling receptor activity created_by: bf creation_date: 2011-11-02T04:52:24Z [Term] id: GO:0038083 name: peptidyl-tyrosine autophosphorylation namespace: biological_process def: "The phosphorylation by a protein of one or more of its own tyrosine amino acid residues, or a tyrosine residue on an identical protein." [PMID:10037737, PMID:10068444, PMID:10940390] subset: gocheck_obsoletion_candidate synonym: "receptor tyrosine kinase autophosphorylation" NARROW [PMID:20432069] synonym: "RTK autophosphorylation" NARROW [PMID:20432069] synonym: "tyrosine autophosphorylation" EXACT [PMID:16431914] is_a: GO:0018108 ! peptidyl-tyrosine phosphorylation is_a: GO:0046777 ! protein autophosphorylation created_by: bf creation_date: 2012-02-01T02:14:18Z [Term] id: GO:0042038 name: peptidyl-histidine methylation, to form tele-methylhistidine namespace: biological_process alt_id: GO:0042261 def: "The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine)." [RESID:AA0317] subset: gocheck_obsoletion_candidate synonym: "peptidyl-histidine tele-methylation" EXACT [] xref: RESID:AA0317 is_a: GO:0018021 ! peptidyl-histidine methylation [Term] id: GO:0042040 name: metal incorporation into metallo-molybdopterin complex namespace: biological_process def: "The incorporation of a metal into a metallo-molybdopterin complex." [GOC:ai] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0042042 name: tungsten incorporation into tungsten-molybdopterin complex namespace: biological_process def: "The incorporation of tungsten into a tungsten-molybdopterin complex." [GOC:ai] subset: gocheck_obsoletion_candidate is_a: GO:0042040 ! metal incorporation into metallo-molybdopterin complex [Term] id: GO:0042077 name: protein phosphate-linked glycosylation via serine namespace: biological_process def: "The glycosylation of peptidyl-serine through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "protein amino acid phosphate-linked glycosylation via serine" EXACT [GOC:bf] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0042264 name: peptidyl-aspartic acid hydroxylation namespace: biological_process def: "The hydroxylation of peptidyl-aspartic acid to form peptidyl-hydroxyaspartic acid." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "peptidyl-aspartic acid/asparagine hydroxylation" BROAD [] is_a: GO:0018126 ! protein hydroxylation is_a: GO:0018197 ! peptidyl-aspartic acid modification [Term] id: GO:0042325 name: regulation of phosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule." [GOC:jl] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_obsoletion_candidate relationship: regulates GO:0016310 ! phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27189" xsd:anyURI [Term] id: GO:0042326 name: negative regulation of phosphorylation namespace: biological_process def: "Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule." [GOC:jl] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_obsoletion_candidate synonym: "down regulation of phosphorylation" EXACT [] synonym: "down-regulation of phosphorylation" EXACT [] synonym: "downregulation of phosphorylation" EXACT [] synonym: "inhibition of phosphorylation" NARROW [] is_a: GO:0042325 ! regulation of phosphorylation relationship: negatively_regulates GO:0016310 ! phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/27189" xsd:anyURI [Term] id: GO:0042501 name: serine phosphorylation of STAT protein namespace: biological_process alt_id: GO:0033136 def: "The process of introducing a phosphate group to a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:jl, PMID:10918594] subset: gocheck_obsoletion_candidate synonym: "serine phosphorylation of STAT3 protein" NARROW [] is_a: GO:0018105 ! peptidyl-serine phosphorylation [Term] id: GO:0042509 name: regulation of tyrosine phosphorylation of STAT protein namespace: biological_process alt_id: GO:0042510 alt_id: GO:0042513 alt_id: GO:0042516 alt_id: GO:0042519 alt_id: GO:0042522 alt_id: GO:0042525 alt_id: GO:0042528 def: "Any process that modulates the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:jl, PMID:11426647] subset: gocheck_obsoletion_candidate synonym: "regulation of tyrosine phosphorylation of Stat1 protein" NARROW [] synonym: "regulation of tyrosine phosphorylation of Stat2 protein" NARROW [] synonym: "regulation of tyrosine phosphorylation of Stat3 protein" NARROW [] synonym: "regulation of tyrosine phosphorylation of Stat4 protein" NARROW [] synonym: "regulation of tyrosine phosphorylation of Stat5 protein" NARROW [] synonym: "regulation of tyrosine phosphorylation of Stat6 protein" NARROW [] synonym: "regulation of tyrosine phosphorylation of Stat7 protein" NARROW [] is_a: GO:0050730 ! regulation of peptidyl-tyrosine phosphorylation relationship: regulates GO:0007260 ! tyrosine phosphorylation of STAT protein property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI [Term] id: GO:0042531 name: positive regulation of tyrosine phosphorylation of STAT protein namespace: biological_process alt_id: GO:0042511 alt_id: GO:0042515 alt_id: GO:0042517 alt_id: GO:0042520 alt_id: GO:0042523 alt_id: GO:0042526 alt_id: GO:0042529 def: "Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:jl, PMID:11426647] subset: gocheck_obsoletion_candidate synonym: "activation of tyrosine phosphorylation of STAT protein" NARROW [] synonym: "activation of tyrosine phosphorylation of Stat1 protein" NARROW [] synonym: "activation of tyrosine phosphorylation of Stat2 protein" NARROW [] synonym: "activation of tyrosine phosphorylation of Stat3 protein" NARROW [] synonym: "activation of tyrosine phosphorylation of Stat4 protein" NARROW [] synonym: "activation of tyrosine phosphorylation of Stat5 protein" NARROW [] synonym: "activation of tyrosine phosphorylation of Stat6 protein" NARROW [] synonym: "activation of tyrosine phosphorylation of Stat7 protein" NARROW [] synonym: "positive regulation of tyrosine phosphorylation of Stat1 protein" NARROW [] synonym: "positive regulation of tyrosine phosphorylation of Stat2 protein" NARROW [] synonym: "positive regulation of tyrosine phosphorylation of Stat3 protein" NARROW [] synonym: "positive regulation of tyrosine phosphorylation of Stat4 protein" NARROW [] synonym: "positive regulation of tyrosine phosphorylation of Stat5 protein" NARROW [] synonym: "positive regulation of tyrosine phosphorylation of Stat6 protein" NARROW [] synonym: "positive regulation of tyrosine phosphorylation of Stat7 protein" NARROW [] synonym: "stimulation of tyrosine phosphorylation of STAT protein" NARROW [] synonym: "stimulation of tyrosine phosphorylation of Stat1 protein" NARROW [] synonym: "stimulation of tyrosine phosphorylation of Stat2 protein" NARROW [] synonym: "stimulation of tyrosine phosphorylation of Stat3 protein" NARROW [] synonym: "stimulation of tyrosine phosphorylation of Stat4 protein" NARROW [] synonym: "stimulation of tyrosine phosphorylation of Stat5 protein" NARROW [] synonym: "stimulation of tyrosine phosphorylation of Stat6 protein" NARROW [] synonym: "stimulation of tyrosine phosphorylation of Stat7 protein" NARROW [] synonym: "up regulation of tyrosine phosphorylation of STAT protein" EXACT [] synonym: "up regulation of tyrosine phosphorylation of Stat1 protein" NARROW [] synonym: "up regulation of tyrosine phosphorylation of Stat2 protein" NARROW [] synonym: "up regulation of tyrosine phosphorylation of Stat3 protein" NARROW [] synonym: "up regulation of tyrosine phosphorylation of Stat4 protein" NARROW [] synonym: "up regulation of tyrosine phosphorylation of Stat5 protein" NARROW [] synonym: "up regulation of tyrosine phosphorylation of Stat6 protein" NARROW [] synonym: "up regulation of tyrosine phosphorylation of Stat7 protein" NARROW [] synonym: "up-regulation of tyrosine phosphorylation of STAT protein" EXACT [] synonym: "up-regulation of tyrosine phosphorylation of Stat1 protein" NARROW [] synonym: "up-regulation of tyrosine phosphorylation of Stat2 protein" NARROW [] synonym: "up-regulation of tyrosine phosphorylation of Stat3 protein" NARROW [] synonym: "up-regulation of tyrosine phosphorylation of Stat4 protein" NARROW [] synonym: "up-regulation of tyrosine phosphorylation of Stat5 protein" NARROW [] synonym: "up-regulation of tyrosine phosphorylation of Stat6 protein" NARROW [] synonym: "up-regulation of tyrosine phosphorylation of Stat7 protein" NARROW [] synonym: "upregulation of tyrosine phosphorylation of STAT protein" EXACT [] synonym: "upregulation of tyrosine phosphorylation of Stat1 protein" NARROW [] synonym: "upregulation of tyrosine phosphorylation of Stat2 protein" NARROW [] synonym: "upregulation of tyrosine phosphorylation of Stat3 protein" NARROW [] synonym: "upregulation of tyrosine phosphorylation of Stat4 protein" NARROW [] synonym: "upregulation of tyrosine phosphorylation of Stat5 protein" NARROW [] synonym: "upregulation of tyrosine phosphorylation of Stat6 protein" NARROW [] synonym: "upregulation of tyrosine phosphorylation of Stat7 protein" NARROW [] is_a: GO:0042509 ! regulation of tyrosine phosphorylation of STAT protein is_a: GO:0050731 ! positive regulation of peptidyl-tyrosine phosphorylation relationship: positively_regulates GO:0007260 ! tyrosine phosphorylation of STAT protein property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI [Term] id: GO:0042532 name: negative regulation of tyrosine phosphorylation of STAT protein namespace: biological_process alt_id: GO:0042512 alt_id: GO:0042514 alt_id: GO:0042518 alt_id: GO:0042521 alt_id: GO:0042524 alt_id: GO:0042527 alt_id: GO:0042530 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein." [GOC:jl, PMID:11426647] subset: gocheck_obsoletion_candidate synonym: "down regulation of tyrosine phosphorylation of STAT protein" EXACT [] synonym: "down regulation of tyrosine phosphorylation of Stat1 protein" NARROW [] synonym: "down regulation of tyrosine phosphorylation of Stat2 protein" NARROW [] synonym: "down regulation of tyrosine phosphorylation of Stat3 protein" NARROW [] synonym: "down regulation of tyrosine phosphorylation of Stat4 protein" NARROW [] synonym: "down regulation of tyrosine phosphorylation of Stat5 protein" NARROW [] synonym: "down regulation of tyrosine phosphorylation of Stat6 protein" NARROW [] synonym: "down regulation of tyrosine phosphorylation of Stat7 protein" NARROW [] synonym: "down-regulation of tyrosine phosphorylation of STAT protein" EXACT [] synonym: "down-regulation of tyrosine phosphorylation of Stat1 protein" NARROW [] synonym: "down-regulation of tyrosine phosphorylation of Stat2 protein" NARROW [] synonym: "down-regulation of tyrosine phosphorylation of Stat3 protein" NARROW [] synonym: "down-regulation of tyrosine phosphorylation of Stat4 protein" NARROW [] synonym: "down-regulation of tyrosine phosphorylation of Stat5 protein" NARROW [] synonym: "down-regulation of tyrosine phosphorylation of Stat6 protein" NARROW [] synonym: "down-regulation of tyrosine phosphorylation of Stat7 protein" NARROW [] synonym: "downregulation of tyrosine phosphorylation of STAT protein" EXACT [] synonym: "downregulation of tyrosine phosphorylation of Stat1 protein" NARROW [] synonym: "downregulation of tyrosine phosphorylation of Stat2 protein" NARROW [] synonym: "downregulation of tyrosine phosphorylation of Stat3 protein" NARROW [] synonym: "downregulation of tyrosine phosphorylation of Stat4 protein" NARROW [] synonym: "downregulation of tyrosine phosphorylation of Stat5 protein" NARROW [] synonym: "downregulation of tyrosine phosphorylation of Stat6 protein" NARROW [] synonym: "downregulation of tyrosine phosphorylation of Stat7 protein" NARROW [] synonym: "inhibition of tyrosine phosphorylation of STAT protein" NARROW [] synonym: "inhibition of tyrosine phosphorylation of Stat1 protein" NARROW [] synonym: "inhibition of tyrosine phosphorylation of Stat2 protein" NARROW [] synonym: "inhibition of tyrosine phosphorylation of Stat3 protein" NARROW [] synonym: "inhibition of tyrosine phosphorylation of Stat4 protein" NARROW [] synonym: "inhibition of tyrosine phosphorylation of Stat5 protein" NARROW [] synonym: "inhibition of tyrosine phosphorylation of Stat6 protein" NARROW [] synonym: "inhibition of tyrosine phosphorylation of Stat7 protein" NARROW [] synonym: "negative regulation of tyrosine phosphorylation of Stat1 protein" NARROW [] synonym: "negative regulation of tyrosine phosphorylation of Stat2 protein" NARROW [] synonym: "negative regulation of tyrosine phosphorylation of Stat3 protein" NARROW [] synonym: "negative regulation of tyrosine phosphorylation of Stat4 protein" NARROW [] synonym: "negative regulation of tyrosine phosphorylation of Stat5 protein" NARROW [] synonym: "negative regulation of tyrosine phosphorylation of Stat6 protein" NARROW [] synonym: "negative regulation of tyrosine phosphorylation of Stat7 protein" NARROW [] is_a: GO:0042509 ! regulation of tyrosine phosphorylation of STAT protein is_a: GO:0050732 ! negative regulation of peptidyl-tyrosine phosphorylation relationship: negatively_regulates GO:0007260 ! tyrosine phosphorylation of STAT protein property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI [Term] id: GO:0042976 name: activation of Janus kinase activity namespace: biological_process alt_id: GO:0010531 alt_id: GO:0042977 def: "The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it." [GOC:jl, PMID:12479803] subset: gocheck_obsoletion_candidate synonym: "activation of JAK protein" EXACT [GOC:dph, GOC:tb] synonym: "activation of JAK protein by tyrosine phosphorylation" EXACT [] synonym: "activation of JAK1 kinase activity" NARROW [] synonym: "activation of JAK1 protein" NARROW [GOC:dph, GOC:tb] synonym: "activation of JAK2 kinase activity" NARROW [] synonym: "activation of JAK2 protein" NARROW [GOC:dph, GOC:tb] synonym: "positive regulation of JAK protein activity by tyrosine phosphorylation" EXACT [] synonym: "tyrosine phosphorylation of JAK protein" EXACT [] synonym: "tyrosine phosphorylation of JAK1 protein" NARROW [GOC:dph, GOC:tb] synonym: "tyrosine phosphorylation of JAK2 protein" NARROW [] is_a: GO:0018108 ! peptidyl-tyrosine phosphorylation is_a: GO:0032147 ! activation of protein kinase activity [Term] id: GO:0043085 name: positive regulation of catalytic activity namespace: biological_process alt_id: GO:0048554 def: "Any process that activates or increases the activity of an enzyme." [GOC:ebc, GOC:jl, GOC:tb, GOC:vw] subset: gocheck_obsoletion_candidate subset: goslim_chembl synonym: "activation of enzyme activity" NARROW [] synonym: "activation of metalloenzyme activity" NARROW [] synonym: "positive regulation of enzyme activity" EXACT [GOC:tb] synonym: "positive regulation of metalloenzyme activity" NARROW [] synonym: "stimulation of enzyme activity" NARROW [] synonym: "stimulation of metalloenzyme activity" NARROW [] synonym: "up regulation of enzyme activity" EXACT [] synonym: "up regulation of metalloenzyme activity" NARROW [] synonym: "up-regulation of enzyme activity" EXACT [] synonym: "up-regulation of metalloenzyme activity" NARROW [] synonym: "upregulation of enzyme activity" EXACT [] synonym: "upregulation of metalloenzyme activity" NARROW [] is_a: GO:0044093 ! positive regulation of molecular function is_a: GO:0050790 ! regulation of catalytic activity [Term] id: GO:0043086 name: negative regulation of catalytic activity namespace: biological_process alt_id: GO:0048553 def: "Any process that stops or reduces the activity of an enzyme." [GOC:ebc, GOC:jl, GOC:tb, GOC:vw] subset: gocheck_obsoletion_candidate synonym: "down regulation of enzyme activity" EXACT [] synonym: "down regulation of metalloenzyme activity" NARROW [] synonym: "down-regulation of enzyme activity" EXACT [] synonym: "down-regulation of metalloenzyme activity" EXACT [] synonym: "downregulation of enzyme activity" EXACT [] synonym: "downregulation of metalloenzyme activity" NARROW [] synonym: "inhibition of enzyme activity" NARROW [] synonym: "inhibition of metalloenzyme activity" NARROW [] synonym: "negative regulation of enzyme activity" EXACT [GOC:tb] synonym: "negative regulation of metalloenzyme activity" NARROW [] is_a: GO:0050790 ! regulation of catalytic activity [Term] id: GO:0043405 name: regulation of MAP kinase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of MAP kinase activity." [GOC:dph, GOC:go_curators] subset: gocheck_obsoletion_candidate synonym: "Regulation of MAPK activity" EXACT [GOC:dph] synonym: "regulation of mitogen activated protein kinase activity" EXACT [] synonym: "regulation of mitogen-activated protein kinase activity" EXACT [] is_a: GO:0071900 ! regulation of protein serine/threonine kinase activity [Term] id: GO:0043406 name: positive regulation of MAP kinase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of MAP kinase activity." [GOC:dph, GOC:go_curators] subset: gocheck_obsoletion_candidate synonym: "positive regulation of mitogen activated protein kinase activity" EXACT [] synonym: "positive regulation of mitogen-activated protein kinase activity" EXACT [] synonym: "stimulation of MAPK activity" NARROW [] synonym: "up regulation of MAPK activity" EXACT [] synonym: "up-regulation of MAPK activity" EXACT [] synonym: "upregulation of MAPK activity" EXACT [] is_a: GO:0043405 ! regulation of MAP kinase activity is_a: GO:0071902 ! positive regulation of protein serine/threonine kinase activity [Term] id: GO:0043407 name: negative regulation of MAP kinase activity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity." [GOC:dph, GOC:go_curators] subset: gocheck_obsoletion_candidate synonym: "down regulation of MAPK activity" EXACT [] synonym: "down-regulation of MAPK activity" EXACT [] synonym: "downregulation of MAPK activity" EXACT [] synonym: "inhibition of MAPK activity" NARROW [] synonym: "negative regulation of mitogen activated protein kinase activity" EXACT [] synonym: "negative regulation of mitogen-activated protein kinase activity" EXACT [] is_a: GO:0043405 ! regulation of MAP kinase activity is_a: GO:0071901 ! negative regulation of protein serine/threonine kinase activity [Term] id: GO:0043412 name: macromolecule modification namespace: biological_process def: "The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties." [GOC:go_curators] subset: gocheck_obsoletion_candidate subset: goslim_pir property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26424" xsd:anyURI [Term] id: GO:0043414 name: macromolecule methylation namespace: biological_process def: "The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule." [GOC:go_curators] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0043433 name: negative regulation of DNA-binding transcription factor activity namespace: biological_process alt_id: GO:1904168 alt_id: GO:2000824 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription." [GOC:jl] subset: gocheck_obsoletion_candidate synonym: "down regulation of transcription factor activity" EXACT [] synonym: "down-regulation of transcription factor activity" EXACT [] synonym: "downregulation of transcription factor activity" EXACT [] synonym: "inhibition of transcription factor activity" NARROW [] synonym: "negative regulation of androgen receptor activity" NARROW [] synonym: "negative regulation of DNA binding transcription factor activity" EXACT [] synonym: "negative regulation of sequence-specific DNA binding transcription factor activity" EXACT [] synonym: "negative regulation of thyroid hormone receptor activity" NARROW [] synonym: "negative regulation of transcription factor activity" BROAD [GOC:dph, GOC:tb] is_a: GO:0051090 ! regulation of DNA-binding transcription factor activity creation_date: 2011-07-15T10:56:12Z [Term] id: GO:0043462 name: regulation of ATP-dependent activity namespace: biological_process def: "Any process that modulates the rate of an ATP-dependent activity." [GOC:jl] subset: gocheck_obsoletion_candidate synonym: "regulation of adenosinetriphosphatase activity" EXACT [] synonym: "regulation of ATPase activity" EXACT [] is_a: GO:0065009 ! regulation of molecular function property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22371" xsd:anyURI [Term] id: GO:0043496 name: regulation of protein homodimerization activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer." [GOC:jl, GOC:tb] comment: Note that protein homodimerization is a molecular function: 'protein homodimerization activity ; GO:0042803'. subset: gocheck_obsoletion_candidate is_a: GO:0065009 ! regulation of molecular function [Term] id: GO:0043506 name: regulation of JUN kinase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of JUN kinase activity." [GOC:jl] subset: gocheck_obsoletion_candidate synonym: "regulation of JUNK activity" EXACT [] is_a: GO:0043405 ! regulation of MAP kinase activity [Term] id: GO:0043507 name: positive regulation of JUN kinase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of JUN kinase activity." [GOC:jl] subset: gocheck_obsoletion_candidate synonym: "positive regulation of JUNK activity" EXACT [] synonym: "stimulation of JNK activity" NARROW [] synonym: "up regulation of JNK activity" EXACT [] synonym: "up-regulation of JNK activity" EXACT [] synonym: "upregulation of JNK activity" EXACT [] is_a: GO:0043406 ! positive regulation of MAP kinase activity is_a: GO:0043506 ! regulation of JUN kinase activity [Term] id: GO:0043508 name: negative regulation of JUN kinase activity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity." [GOC:jl] subset: gocheck_obsoletion_candidate synonym: "down regulation of JNK activity" EXACT [] synonym: "down-regulation of JNK activity" EXACT [] synonym: "downregulation of JNK activity" EXACT [] synonym: "inhibition of JNK activity" NARROW [] synonym: "negative regulation of JUNK activity" EXACT [] is_a: GO:0043407 ! negative regulation of MAP kinase activity is_a: GO:0043506 ! regulation of JUN kinase activity [Term] id: GO:0043543 name: protein acylation namespace: biological_process def: "The addition of an acyl group, any group or radical of the form RCO- where R is an organic group, to a protein amino acid." [GOC:jl] subset: gocheck_obsoletion_candidate subset: goslim_yeast synonym: "protein amino acid acylation" EXACT [GOC:bf] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0043547 name: positive regulation of GTPase activity namespace: biological_process alt_id: GO:0032320 alt_id: GO:0032321 alt_id: GO:0032850 alt_id: GO:0032851 alt_id: GO:0032852 alt_id: GO:0032853 alt_id: GO:0032854 alt_id: GO:0032855 alt_id: GO:0043089 def: "Any process that activates or increases the activity of a GTPase." [GOC:jl, GOC:mah] subset: gocheck_obsoletion_candidate synonym: "activation of GTPase activity" NARROW [] synonym: "positive regulation of ARF GTPase activity" NARROW [] synonym: "positive regulation of Cdc42 GTPase activity" NARROW [] synonym: "positive regulation of Rab GTPase activity" NARROW [] synonym: "positive regulation of Rac GTPase activity" NARROW [] synonym: "positive regulation of Ral GTPase activity" NARROW [] synonym: "positive regulation of Ran GTPase activity" NARROW [] synonym: "positive regulation of Rap GTPase activity" NARROW [] synonym: "positive regulation of Ras GTPase activity" NARROW [] synonym: "positive regulation of Rho GTPase activity" NARROW [] synonym: "stimulation of ARF GTPase activity" NARROW [] synonym: "stimulation of Cdc42 GTPase activity" NARROW [] synonym: "stimulation of GTPase activity" NARROW [] synonym: "stimulation of Rab GTPase activity" NARROW [] synonym: "stimulation of Rac GTPase activity" NARROW [] synonym: "stimulation of Ral GTPase activity" NARROW [] synonym: "stimulation of Ran GTPase activity" NARROW [] synonym: "stimulation of Rap GTPase activity" NARROW [] synonym: "stimulation of Ras GTPase activity" NARROW [] synonym: "stimulation of Rho GTPase activity" NARROW [] synonym: "up regulation of ARF GTPase activity" NARROW [] synonym: "up regulation of Cdc42 GTPase activity" NARROW [] synonym: "up regulation of GTPase activity" EXACT [] synonym: "up regulation of Rab GTPase activity" NARROW [] synonym: "up regulation of Rac GTPase activity" NARROW [] synonym: "up regulation of Ral GTPase activity" NARROW [] synonym: "up regulation of Ran GTPase activity" NARROW [] synonym: "up regulation of Rap GTPase activity" NARROW [] synonym: "up regulation of Ras GTPase activity" NARROW [] synonym: "up regulation of Rho GTPase activity" NARROW [] synonym: "up-regulation of ARF GTPase activity" NARROW [] synonym: "up-regulation of Cdc42 GTPase activity" NARROW [] synonym: "up-regulation of GTPase activity" EXACT [] synonym: "up-regulation of Rab GTPase activity" NARROW [] synonym: "up-regulation of Rac GTPase activity" NARROW [] synonym: "up-regulation of Ral GTPase activity" NARROW [] synonym: "up-regulation of Ran GTPase activity" NARROW [] synonym: "up-regulation of Rap GTPase activity" NARROW [] synonym: "up-regulation of Ras GTPase activity" NARROW [] synonym: "up-regulation of Rho GTPase activity" NARROW [] synonym: "upregulation of ARF GTPase activity" NARROW [] synonym: "upregulation of Cdc42 GTPase activity" NARROW [] synonym: "upregulation of GTPase activity" EXACT [] synonym: "upregulation of Rab GTPase activity" NARROW [] synonym: "upregulation of Rac GTPase activity" NARROW [] synonym: "upregulation of Ral GTPase activity" NARROW [] synonym: "upregulation of Ran GTPase activity" NARROW [] synonym: "upregulation of Rap GTPase activity" NARROW [] synonym: "upregulation of Ras GTPase activity" NARROW [] synonym: "upregulation of Rho GTPase activity" NARROW [] is_a: GO:0051345 ! positive regulation of hydrolase activity [Term] id: GO:0043549 name: regulation of kinase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:bf] subset: gocheck_obsoletion_candidate is_a: GO:0042325 ! regulation of phosphorylation is_a: GO:0051338 ! regulation of transferase activity [Term] id: GO:0043550 name: regulation of lipid kinase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid." [GOC:bf] subset: gocheck_obsoletion_candidate is_a: GO:0043549 ! regulation of kinase activity [Term] id: GO:0044093 name: positive regulation of molecular function namespace: biological_process def: "Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GO:jl] subset: gocheck_obsoletion_candidate is_a: GO:0065009 ! regulation of molecular function created_by: jl creation_date: 2009-04-21T04:11:06Z [Term] id: GO:0044361 name: negative regulation of voltage-gated potassium channel activity in another organism namespace: biological_process def: "Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism." [GOC:jl] subset: gocheck_obsoletion_candidate synonym: "negative regulation of voltage-gated potassium channel activity in other organism" EXACT [] created_by: jl creation_date: 2011-10-27T02:11:52Z [Term] id: GO:0044387 name: negative regulation of protein kinase activity by regulation of protein phosphorylation namespace: biological_process def: "The stopping, prevention, or reduction in frequency, rate or extent of protein kinase activity as a result of regulating the phosphorylation status of that protein kinase." [GOC:jl] subset: gocheck_obsoletion_candidate is_a: GO:0006469 ! negative regulation of protein kinase activity created_by: jl creation_date: 2011-12-13T04:49:36Z [Term] id: GO:0044394 name: protein malonylation namespace: biological_process def: "The modification of a protein amino acid by the addition of a malonyl (CO-CH2-CO) group." [GOC:sp] subset: gocheck_obsoletion_candidate is_a: GO:0043543 ! protein acylation created_by: bf creation_date: 2011-12-12T09:26:37Z [Term] id: GO:0044489 name: negative regulation of voltage-gated sodium channel activity in another organism namespace: biological_process def: "Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism." [GOC:fj, GOC:jl, PMID:21781281] subset: gocheck_obsoletion_candidate synonym: "negative regulation of voltage-gated sodium channel activity in other organism" EXACT [] created_by: jl creation_date: 2012-02-01T12:21:02Z [Term] id: GO:0044490 name: positive regulation of voltage-gated sodium channel activity in another organism namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism." [GOC:fj, GOC:jl, PMID:21781281] subset: gocheck_obsoletion_candidate synonym: "positive regulation of voltage-gated sodium channel activity in other organism" EXACT [] created_by: jl creation_date: 2012-02-01T12:21:26Z [Term] id: GO:0044505 name: positive regulation of G protein-coupled receptor activity in another organism namespace: biological_process def: "A process that activates or increases the frequency, rate or extent of the activity of a G protein-coupled receptor in a second organism." [GOC:fj, GOC:jl, PMID:8405712] subset: gocheck_obsoletion_candidate synonym: "positive regulation of G protein-coupled receptor activity in other organism" EXACT [] synonym: "positive regulation of G-protein coupled receptor activity in other organism" EXACT [] is_a: GO:2000273 ! positive regulation of signaling receptor activity created_by: jl creation_date: 2012-02-23T04:24:17Z [Term] id: GO:0044524 name: protein sulfhydration namespace: biological_process def: "The modification of a protein amino acid by the addition of sulfur." [GOC:jl, GOC:jsg, PMID:19903941, PMID:22169477, PMID:8161529] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification created_by: jl creation_date: 2012-03-15T09:39:33Z [Term] id: GO:0044525 name: peptidyl-cystine sulfhydration namespace: biological_process def: "The modification of a peptidyl-cystine residue in a protein by the addition of sulfur, to form peptidyl-cysteine persulfide." [GOC:jl, GOC:jsg] subset: gocheck_obsoletion_candidate is_a: GO:0044524 ! protein sulfhydration created_by: jl creation_date: 2012-03-15T09:44:07Z [Term] id: GO:0044601 name: protein denucleotidylation namespace: biological_process def: "The removal of a nucleotide from a protein amino acid." [GOC:sp, PMID:21734656] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification created_by: jl creation_date: 2012-05-01T04:13:54Z [Term] id: GO:0044602 name: protein deadenylylation namespace: biological_process def: "The removal of an adenylyl group (adenosine 5'-monophosphate; AMP) from a protein amino acid." [GOC:sp, PMID:21734656] subset: gocheck_obsoletion_candidate synonym: "protein deAMPylation" EXACT [PMID:21734656] is_a: GO:0044601 ! protein denucleotidylation created_by: jl creation_date: 2012-05-01T04:16:22Z [Term] id: GO:0045234 name: protein palmitoleylation namespace: biological_process alt_id: GO:0045235 def: "The covalent attachment of a palmitoleyl group to a protein." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "protein amino acid palmitoleylation" EXACT [GOC:bf] is_a: GO:0006497 ! protein lipidation is_a: GO:0043543 ! protein acylation [Term] id: GO:0045736 name: negative regulation of cyclin-dependent protein serine/threonine kinase activity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity." [GOC:go_curators, GOC:pr] subset: gocheck_obsoletion_candidate is_a: GO:0000079 ! regulation of cyclin-dependent protein serine/threonine kinase activity is_a: GO:0071901 ! negative regulation of protein serine/threonine kinase activity is_a: GO:1904030 ! negative regulation of cyclin-dependent protein kinase activity [Term] id: GO:0045737 name: positive regulation of cyclin-dependent protein serine/threonine kinase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of CDK activity." [GOC:go_curators, GOC:pr] subset: gocheck_obsoletion_candidate synonym: "activation of cyclin-dependent protein kinase activity" BROAD [] synonym: "positive regulation of CDK activity" BROAD [] synonym: "positive regulation of cyclin-dependent protein kinase activity" BROAD [GOC:pr] synonym: "stimulation of cyclin-dependent protein kinase activity" BROAD [] synonym: "up regulation of cyclin-dependent protein kinase activity" BROAD [] synonym: "up-regulation of cyclin-dependent protein kinase activity" BROAD [] synonym: "upregulation of cyclin-dependent protein kinase activity" BROAD [] is_a: GO:0000079 ! regulation of cyclin-dependent protein serine/threonine kinase activity is_a: GO:0071902 ! positive regulation of protein serine/threonine kinase activity is_a: GO:1904031 ! positive regulation of cyclin-dependent protein kinase activity [Term] id: GO:0045741 name: positive regulation of epidermal growth factor-activated receptor activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of EGF-activated receptor activity." [GOC:go_curators] subset: gocheck_obsoletion_candidate synonym: "activation of epidermal growth factor receptor activity" NARROW [] synonym: "positive regulation of EGF receptor activity" EXACT [] synonym: "positive regulation of EGFR activity" EXACT [] synonym: "positive regulation of epidermal growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] synonym: "stimulation of epidermal growth factor receptor activity" NARROW [] synonym: "up regulation of epidermal growth factor receptor activity" EXACT [] synonym: "up-regulation of epidermal growth factor receptor activity" EXACT [] synonym: "upregulation of epidermal growth factor receptor activity" EXACT [] is_a: GO:0007176 ! regulation of epidermal growth factor-activated receptor activity is_a: GO:0061098 ! positive regulation of protein tyrosine kinase activity is_a: GO:2000273 ! positive regulation of signaling receptor activity property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/25326" xsd:anyURI property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI [Term] id: GO:0045761 name: regulation of adenylate cyclase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of adenylate cyclase activity." [GOC:go_curators] subset: gocheck_obsoletion_candidate synonym: "adenylate cyclase regulator" RELATED [] synonym: "regulation of adenylyl cyclase activity" EXACT [] is_a: GO:0050790 ! regulation of catalytic activity [Term] id: GO:0045762 name: positive regulation of adenylate cyclase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity." [GOC:go_curators] subset: gocheck_obsoletion_candidate synonym: "adenylate cyclase activator" RELATED [] synonym: "positive regulation of adenylyl cyclase activity" EXACT [] synonym: "stimulation of adenylate cyclase activity" NARROW [] synonym: "up regulation of adenylate cyclase activity" EXACT [] synonym: "up-regulation of adenylate cyclase activity" EXACT [] synonym: "upregulation of adenylate cyclase activity" EXACT [] is_a: GO:0031281 ! positive regulation of cyclase activity is_a: GO:0045761 ! regulation of adenylate cyclase activity is_a: GO:0051349 ! positive regulation of lyase activity [Term] id: GO:0045859 name: regulation of protein kinase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein kinase activity." [GOC:go_curators] subset: gocheck_obsoletion_candidate is_a: GO:0001932 ! regulation of protein phosphorylation is_a: GO:0043549 ! regulation of kinase activity [Term] id: GO:0045860 name: positive regulation of protein kinase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein kinase activity." [GOC:go_curators] subset: gocheck_obsoletion_candidate synonym: "stimulation of protein kinase activity" NARROW [] synonym: "up regulation of protein kinase activity" EXACT [] synonym: "up-regulation of protein kinase activity" EXACT [] synonym: "upregulation of protein kinase activity" EXACT [] is_a: GO:0001934 ! positive regulation of protein phosphorylation is_a: GO:0033674 ! positive regulation of kinase activity is_a: GO:0045859 ! regulation of protein kinase activity [Term] id: GO:0046777 name: protein autophosphorylation namespace: biological_process def: "The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation)." [ISBN:0198506732] subset: gocheck_obsoletion_candidate synonym: "protein amino acid autophosphorylation" EXACT [GOC:bf] xref: Wikipedia:Autophosphorylation is_a: GO:0006468 ! protein phosphorylation [Term] id: GO:0046944 name: protein carbamoylation namespace: biological_process def: "The addition of a carbamoyl group to a protein amino acid. A carbamoyl group is the acyl group -CO-NH2." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "protein amino acid carbamoylation" EXACT [GOC:bf] is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0050730 name: regulation of peptidyl-tyrosine phosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine." [GOC:ai] subset: gocheck_obsoletion_candidate is_a: GO:0001932 ! regulation of protein phosphorylation relationship: regulates GO:0018108 ! peptidyl-tyrosine phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI [Term] id: GO:0050731 name: positive regulation of peptidyl-tyrosine phosphorylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "activation of peptidyl-tyrosine phosphorylation" NARROW [] synonym: "stimulation of peptidyl-tyrosine phosphorylation" NARROW [] synonym: "up regulation of peptidyl-tyrosine phosphorylation" EXACT [] synonym: "up-regulation of peptidyl-tyrosine phosphorylation" EXACT [] synonym: "upregulation of peptidyl-tyrosine phosphorylation" EXACT [] is_a: GO:0001934 ! positive regulation of protein phosphorylation is_a: GO:0050730 ! regulation of peptidyl-tyrosine phosphorylation relationship: positively_regulates GO:0018108 ! peptidyl-tyrosine phosphorylation [Term] id: GO:0050732 name: negative regulation of peptidyl-tyrosine phosphorylation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "down regulation of peptidyl-tyrosine phosphorylation" EXACT [] synonym: "down-regulation of peptidyl-tyrosine phosphorylation" EXACT [] synonym: "downregulation of peptidyl-tyrosine phosphorylation" EXACT [] synonym: "inhibition of peptidyl-tyrosine phosphorylation" NARROW [] is_a: GO:0001933 ! negative regulation of protein phosphorylation is_a: GO:0050730 ! regulation of peptidyl-tyrosine phosphorylation relationship: negatively_regulates GO:0018108 ! peptidyl-tyrosine phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI [Term] id: GO:0050790 name: regulation of catalytic activity namespace: biological_process alt_id: GO:0048552 def: "Any process that modulates the activity of an enzyme." [GOC:ai, GOC:ebc, GOC:vw] subset: gocheck_obsoletion_candidate subset: goslim_chembl synonym: "regulation of enzyme activity" EXACT [] synonym: "regulation of metalloenzyme activity" NARROW [] is_a: GO:0065009 ! regulation of molecular function [Term] id: GO:0050844 name: peptidyl-selenocysteine modification namespace: biological_process def: "The modification of peptidyl-selenocysteine." [GOC:ai] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0050989 name: N-terminal protein amino acid carboxylation namespace: biological_process def: "The carboxylation of the N-terminal amino acid of proteins." [GOC:ai] subset: gocheck_obsoletion_candidate is_a: GO:0031365 ! N-terminal protein amino acid modification [Term] id: GO:0050990 name: N-terminal protein amino acid carbamoylation namespace: biological_process def: "The carbamoylation of the N-terminal amino acid of proteins." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "N-terminal protein amino acid carbamylation" EXACT [] is_a: GO:0031365 ! N-terminal protein amino acid modification [Term] id: GO:0050999 name: regulation of nitric-oxide synthase activity namespace: biological_process def: "Any process that modulates the activity of the enzyme nitric-oxide synthase." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "nitric-oxide synthase regulator" EXACT [] synonym: "NOS regulator" EXACT [] synonym: "regulation of NOS activity" EXACT [] is_a: GO:0051341 ! regulation of oxidoreductase activity [Term] id: GO:0051000 name: positive regulation of nitric-oxide synthase activity namespace: biological_process def: "Any process that activates or increases the activity of the enzyme nitric-oxide synthase." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "activation of nitric-oxide synthase activity" NARROW [] synonym: "nitric-oxide synthase activator" EXACT [] synonym: "NOS activator" EXACT [] synonym: "positive regulation of NOS activity" EXACT [] synonym: "stimulation of nitric-oxide synthase activity" NARROW [] synonym: "up regulation of nitric-oxide synthase activity" EXACT [] synonym: "up-regulation of nitric-oxide synthase activity" EXACT [] synonym: "upregulation of nitric-oxide synthase activity" EXACT [] is_a: GO:0032770 ! positive regulation of monooxygenase activity is_a: GO:0050999 ! regulation of nitric-oxide synthase activity [Term] id: GO:0051001 name: negative regulation of nitric-oxide synthase activity namespace: biological_process def: "Any process that stops or reduces the activity of the enzyme nitric-oxide synthase." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "down regulation of nitric-oxide synthase activity" EXACT [] synonym: "down-regulation of nitric-oxide synthase activity" EXACT [] synonym: "downregulation of nitric-oxide synthase activity" EXACT [] synonym: "inhibition of nitric-oxide synthase activity" NARROW [] synonym: "negative regulation of NOS activity" EXACT [] synonym: "nitric-oxide synthase inhibitor" NARROW [] synonym: "NOS inhibitor" NARROW [] is_a: GO:0032769 ! negative regulation of monooxygenase activity is_a: GO:0050999 ! regulation of nitric-oxide synthase activity [Term] id: GO:0051005 name: negative regulation of lipoprotein lipase activity namespace: biological_process def: "Any process that stops or reduces the activity of the enzyme lipoprotein lipase." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "down regulation of lipoprotein lipase activity" EXACT [] synonym: "down-regulation of lipoprotein lipase activity" EXACT [] synonym: "downregulation of lipoprotein lipase activity" EXACT [] synonym: "inhibition of lipoprotein lipase activity" NARROW [] is_a: GO:0060192 ! negative regulation of lipase activity [Term] id: GO:0051006 name: positive regulation of lipoprotein lipase activity namespace: biological_process def: "Any process that activates or increases the activity of the enzyme lipoprotein lipase." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "activation of lipoprotein lipase activity" NARROW [] synonym: "stimulation of lipoprotein lipase activity" NARROW [] synonym: "up regulation of lipoprotein lipase activity" EXACT [] synonym: "up-regulation of lipoprotein lipase activity" EXACT [] synonym: "upregulation of lipoprotein lipase activity" EXACT [] is_a: GO:0061365 ! positive regulation of triglyceride lipase activity [Term] id: GO:0051090 name: regulation of DNA-binding transcription factor activity namespace: biological_process alt_id: GO:1904167 alt_id: GO:2000823 def: "Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "regulation of androgen receptor activity" NARROW [] synonym: "regulation of DNA binding transcription factor activity" EXACT [] synonym: "regulation of sequence-specific DNA binding transcription factor activity" EXACT [] synonym: "regulation of thyroid hormone receptor activity" NARROW [] synonym: "regulation of transcription factor activity" BROAD [GOC:dph, GOC:tb] xref: Reactome:R-HSA-9708530 "Regulation of BACH1 activity" is_a: GO:0065009 ! regulation of molecular function [Term] id: GO:0051091 name: positive regulation of DNA-binding transcription factor activity namespace: biological_process alt_id: GO:1904169 def: "Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "activation of transcription factor activity" NARROW [] synonym: "positive regulation of DNA binding transcription factor activity" EXACT [] synonym: "positive regulation of sequence-specific DNA binding transcription factor activity" EXACT [] synonym: "positive regulation of thyroid hormone receptor activity" NARROW [] synonym: "positive regulation of transcription factor activity" BROAD [GOC:dph, GOC:tb] synonym: "stimulation of transcription factor activity" NARROW [] synonym: "up regulation of transcription factor activity" EXACT [] synonym: "up-regulation of transcription factor activity" EXACT [] synonym: "upregulation of transcription factor activity" EXACT [] is_a: GO:0044093 ! positive regulation of molecular function is_a: GO:0051090 ! regulation of DNA-binding transcription factor activity created_by: rph creation_date: 2015-04-22T12:22:16Z [Term] id: GO:0051092 name: positive regulation of NF-kappaB transcription factor activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB." [GOC:dph, GOC:tb, PMID:15087454, PMID:15170030] subset: gocheck_obsoletion_candidate synonym: "activation of NF-kappaB" EXACT [] synonym: "activation of NF-kappaB transcription factor" EXACT [GOC:dph, GOC:tb] synonym: "NF-kappaB activation" EXACT [] is_a: GO:0051091 ! positive regulation of DNA-binding transcription factor activity [Term] id: GO:0051096 name: positive regulation of helicase activity namespace: biological_process def: "Any process that activates or increases the activity of a helicase." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "activation of helicase activity" NARROW [] synonym: "stimulation of helicase activity" NARROW [] synonym: "up regulation of helicase activity" EXACT [] synonym: "up-regulation of helicase activity" EXACT [] synonym: "upregulation of helicase activity" EXACT [] is_a: GO:0032781 ! positive regulation of ATP-dependent activity is_a: GO:0043085 ! positive regulation of catalytic activity [Term] id: GO:0051097 name: negative regulation of helicase activity namespace: biological_process def: "Any process that stops or reduces the activity of a helicase." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "down regulation of helicase activity" EXACT [] synonym: "down-regulation of helicase activity" EXACT [] synonym: "downregulation of helicase activity" EXACT [] synonym: "inhibition of helicase activity" NARROW [] is_a: GO:0032780 ! negative regulation of ATP-dependent activity is_a: GO:0043086 ! negative regulation of catalytic activity [Term] id: GO:0051111 name: peptidyl-histidine adenylylation namespace: biological_process def: "The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine) or peptidyl-3'-(phospho-5'-adenosine)-L-histidine (otherwise known as pi-AMP-histidine, pros-AMP-histidine)." [RESID:AA0371] subset: gocheck_obsoletion_candidate xref: RESID:AA0371 is_a: GO:0018117 ! protein adenylylation is_a: GO:0018202 ! peptidyl-histidine modification [Term] id: GO:0051114 name: peptidyl-histidine uridylylation namespace: biological_process def: "The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine) or peptidyl-3'-(phospho-5'-uridine)-L-histidine (otherwise known as pi-UMP-histidine, pros-UMP-histidine)." [RESID:AA0372] subset: gocheck_obsoletion_candidate xref: RESID:AA0372 is_a: GO:0018177 ! protein uridylylation is_a: GO:0018202 ! peptidyl-histidine modification [Term] id: GO:0051336 name: regulation of hydrolase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "hydrolase regulator" EXACT [] is_a: GO:0050790 ! regulation of catalytic activity [Term] id: GO:0051338 name: regulation of transferase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [GOC:ai] comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead. subset: gocheck_obsoletion_candidate synonym: "transferase regulator" EXACT [] is_a: GO:0050790 ! regulation of catalytic activity [Term] id: GO:0051341 name: regulation of oxidoreductase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "oxidoreductase regulator" EXACT [] is_a: GO:0050790 ! regulation of catalytic activity [Term] id: GO:0051343 name: positive regulation of cyclic-nucleotide phosphodiesterase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate." [GOC:ai, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "3',5' cyclic nucleotide phosphodiesterase activator" EXACT [] synonym: "3',5'-cyclic-AMP phosphodiesterase activator" NARROW [] synonym: "activation of cyclic nucleotide phosphodiesterase activity" NARROW [] synonym: "cAMP phosphodiesterase activator" NARROW [] synonym: "phosphodiesterase activator" RELATED [] synonym: "positive regulation of 3',5' cyclic nucleotide phosphodiesterase activity" EXACT [] synonym: "positive regulation of 3',5'-cyclic-AMP phosphodiesterase activity" NARROW [] synonym: "positive regulation of cAMP phosphodiesterase activity" NARROW [] synonym: "positive regulation of cGMP phosphodiesterase activity" NARROW [GOC:tb] synonym: "positive regulation of cyclic nucleotide phosphodiesterase activity" EXACT [GOC:tb] synonym: "stimulation of cyclic nucleotide phosphodiesterase activity" NARROW [] synonym: "up regulation of cyclic nucleotide phosphodiesterase activity" EXACT [] synonym: "up-regulation of cyclic nucleotide phosphodiesterase activity" EXACT [] synonym: "upregulation of cyclic nucleotide phosphodiesterase activity" EXACT [] is_a: GO:0051345 ! positive regulation of hydrolase activity [Term] id: GO:0051344 name: negative regulation of cyclic-nucleotide phosphodiesterase activity namespace: biological_process def: "Any process that stops or reduces the rate of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate." [GOC:ai, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "3',5' cyclic nucleotide phosphodiesterase inhibitor" EXACT [] synonym: "3',5'-cyclic-AMP phosphodiesterase inhibitor" NARROW [] synonym: "cAMP phosphodiesterase inhibitor" NARROW [] synonym: "down regulation of cyclic nucleotide phosphodiesterase activity" EXACT [] synonym: "down-regulation of cyclic nucleotide phosphodiesterase activity" EXACT [] synonym: "downregulation of cyclic nucleotide phosphodiesterase activity" EXACT [] synonym: "inhibition of cyclic nucleotide phosphodiesterase activity" NARROW [] synonym: "negative regulation of 3',5' cyclic nucleotide phosphodiesterase activity" EXACT [] synonym: "negative regulation of 3',5'-cyclic-AMP phosphodiesterase activity" NARROW [] synonym: "negative regulation of cAMP phosphodiesterase activity" NARROW [] synonym: "negative regulation of cGMP phosphodiesterase activity" NARROW [GOC:tb] synonym: "negative regulation of cyclic nucleotide phosphodiesterase activity" EXACT [GOC:tb] synonym: "phosphodiesterase inhibitor" RELATED [] is_a: GO:0051346 ! negative regulation of hydrolase activity [Term] id: GO:0051345 name: positive regulation of hydrolase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "activation of hydrolase activity" NARROW [] synonym: "hydrolase activator" EXACT [] synonym: "stimulation of hydrolase activity" NARROW [] synonym: "up regulation of hydrolase activity" EXACT [] synonym: "up-regulation of hydrolase activity" EXACT [] synonym: "upregulation of hydrolase activity" EXACT [] is_a: GO:0043085 ! positive regulation of catalytic activity is_a: GO:0051336 ! regulation of hydrolase activity [Term] id: GO:0051346 name: negative regulation of hydrolase activity namespace: biological_process def: "Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "down regulation of hydrolase activity" EXACT [] synonym: "down-regulation of hydrolase activity" EXACT [] synonym: "downregulation of hydrolase activity" EXACT [] synonym: "hydrolase inhibitor" EXACT [] synonym: "inhibition of hydrolase activity" NARROW [] is_a: GO:0043086 ! negative regulation of catalytic activity is_a: GO:0051336 ! regulation of hydrolase activity [Term] id: GO:0051347 name: positive regulation of transferase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor." [GOC:ai] comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead. subset: gocheck_obsoletion_candidate synonym: "activation of transferase activity" NARROW [] synonym: "stimulation of transferase activity" NARROW [] synonym: "transferase activator" EXACT [] synonym: "up regulation of transferase activity" EXACT [] synonym: "up-regulation of transferase activity" EXACT [] synonym: "upregulation of transferase activity" EXACT [] is_a: GO:0043085 ! positive regulation of catalytic activity is_a: GO:0051338 ! regulation of transferase activity [Term] id: GO:0051348 name: negative regulation of transferase activity namespace: biological_process def: "Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor." [GOC:ai] comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead. subset: gocheck_obsoletion_candidate synonym: "down regulation of transferase activity" EXACT [] synonym: "down-regulation of transferase activity" EXACT [] synonym: "downregulation of transferase activity" EXACT [] synonym: "inhibition of transferase activity" NARROW [] synonym: "transferase inhibitor" EXACT [] is_a: GO:0043086 ! negative regulation of catalytic activity is_a: GO:0051338 ! regulation of transferase activity [Term] id: GO:0051349 name: positive regulation of lyase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "activation of lyase activity" NARROW [] synonym: "lyase activator" EXACT [] synonym: "stimulation of lyase activity" NARROW [] synonym: "up regulation of lyase activity" EXACT [] synonym: "up-regulation of lyase activity" EXACT [] synonym: "upregulation of lyase activity" EXACT [] is_a: GO:0043085 ! positive regulation of catalytic activity [Term] id: GO:0051350 name: negative regulation of lyase activity namespace: biological_process def: "Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "down regulation of lyase activity" EXACT [] synonym: "down-regulation of lyase activity" EXACT [] synonym: "downregulation of lyase activity" EXACT [] synonym: "inhibition of lyase activity" NARROW [] synonym: "lyase inhibitor" EXACT [] is_a: GO:0043086 ! negative regulation of catalytic activity [Term] id: GO:0051351 name: positive regulation of ligase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "activation of ligase activity" NARROW [] synonym: "ligase activator" EXACT [] synonym: "stimulation of ligase activity" NARROW [] synonym: "up regulation of ligase activity" EXACT [] synonym: "up-regulation of ligase activity" EXACT [] synonym: "upregulation of ligase activity" EXACT [] is_a: GO:0043085 ! positive regulation of catalytic activity [Term] id: GO:0051353 name: positive regulation of oxidoreductase activity namespace: biological_process alt_id: GO:0009391 def: "Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "activation of oxidoreductase activity" NARROW [] synonym: "oxidoreductase activator" EXACT [] synonym: "ribonucleotide reductase activating enzyme activity" NARROW [] synonym: "stimulation of oxidoreductase activity" NARROW [] synonym: "up regulation of oxidoreductase activity" EXACT [] synonym: "up-regulation of oxidoreductase activity" EXACT [] synonym: "upregulation of oxidoreductase activity" EXACT [] is_a: GO:0043085 ! positive regulation of catalytic activity is_a: GO:0051341 ! regulation of oxidoreductase activity [Term] id: GO:0051354 name: negative regulation of oxidoreductase activity namespace: biological_process def: "Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "down regulation of oxidoreductase activity" EXACT [] synonym: "down-regulation of oxidoreductase activity" EXACT [] synonym: "downregulation of oxidoreductase activity" EXACT [] synonym: "inhibition of oxidoreductase activity" NARROW [] synonym: "oxidoreductase inhibitor" EXACT [] is_a: GO:0043086 ! negative regulation of catalytic activity is_a: GO:0051341 ! regulation of oxidoreductase activity [Term] id: GO:0051366 name: protein decanoylation namespace: biological_process def: "The modification of a protein amino acid by formation of an ester or amide with decanoic acid." [GOC:jsg] subset: gocheck_obsoletion_candidate synonym: "protein amino acid decanoylation" EXACT [GOC:bf] is_a: GO:0006497 ! protein lipidation is_a: GO:0043543 ! protein acylation [Term] id: GO:0051394 name: regulation of nerve growth factor receptor activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "regulation of NGF receptor activity" EXACT [] is_a: GO:0010469 ! regulation of signaling receptor activity [Term] id: GO:0051438 name: regulation of ubiquitin-protein transferase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of ubiquitin transferase activity." [GOC:ai, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "anaphase-promoting complex regulator" NARROW [] synonym: "APC regulator" NARROW [] synonym: "regulation of ubiquitin transferase activity" EXACT [GOC:tb] synonym: "SCF complex regulator" NARROW [] synonym: "ubiquitin transferase regulator" RELATED [] synonym: "ubiquitin-protein transferase regulator" RELATED [] is_a: GO:0051338 ! regulation of transferase activity [Term] id: GO:0051443 name: positive regulation of ubiquitin-protein transferase activity namespace: biological_process def: "Any process that activates, maintains or increases the rate of ubiquitin transferase activity." [GOC:ai, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "activation of ubiquitin transferase activity" NARROW [] synonym: "anaphase promoting complex activator" NARROW [] synonym: "anaphase-promoting complex activator" NARROW [] synonym: "APC activation" NARROW [] synonym: "APC activator" NARROW [] synonym: "positive regulation of ubiquitin transferase activity" EXACT [GOC:tb] synonym: "SCF complex activator" NARROW [] synonym: "stimulation of ubiquitin transferase activity" NARROW [] synonym: "ubiquitin transferase activator" NARROW [] synonym: "up regulation of ubiquitin ligase activity" RELATED [] synonym: "up-regulation of ubiquitin transferase activity" EXACT [] synonym: "upregulation of ubiquitin transferase activity" EXACT [] is_a: GO:0031401 ! positive regulation of protein modification process is_a: GO:0051347 ! positive regulation of transferase activity is_a: GO:0051438 ! regulation of ubiquitin-protein transferase activity [Term] id: GO:0051444 name: negative regulation of ubiquitin-protein transferase activity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin transferase activity." [GOC:ai, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "anaphase promoting complex inhibition" NARROW [] synonym: "anaphase promoting complex inhibitor" NARROW [] synonym: "anaphase-promoting complex inhibition" NARROW [] synonym: "anaphase-promoting complex inhibitor" NARROW [] synonym: "APC inhibition" NARROW [] synonym: "APC inhibitor" NARROW [] synonym: "down regulation of ubiquitin transferase activity" EXACT [] synonym: "down-regulation of ubiquitin transferase activity" EXACT [] synonym: "downregulation of ubiquitin transferase activity" EXACT [] synonym: "inhibition of ubiquitin transferase activity" NARROW [] synonym: "negative regulation of ubiquitin transferase activity" EXACT [GOC:tb] synonym: "SCF complex inhibitor" NARROW [] synonym: "ubiquitin transferase inhibitor" NARROW [] is_a: GO:0031400 ! negative regulation of protein modification process is_a: GO:0051348 ! negative regulation of transferase activity is_a: GO:0051438 ! regulation of ubiquitin-protein transferase activity [Term] id: GO:0051697 name: protein delipidation namespace: biological_process def: "The breakage of covalent bonds to detach lipid groups from a protein." [GOC:ai] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification [Term] id: GO:0052547 name: regulation of peptidase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins." [GOC:ai] subset: gocheck_obsoletion_candidate synonym: "peptidase regulator activity" RELATED [] is_a: GO:0051336 ! regulation of hydrolase activity [Term] id: GO:0052548 name: regulation of endopeptidase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins." [GOC:ai, GOC:hjd] subset: gocheck_obsoletion_candidate synonym: "protease regulator activity" NARROW [] is_a: GO:0052547 ! regulation of peptidase activity [Term] id: GO:0060192 name: negative regulation of lipase activity namespace: biological_process def: "Any process that decreases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0051346 ! negative regulation of hydrolase activity [Term] id: GO:0060193 name: positive regulation of lipase activity namespace: biological_process def: "Any process that increases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0051345 ! positive regulation of hydrolase activity [Term] id: GO:0060254 name: regulation of N-terminal protein palmitoylation namespace: biological_process def: "Any process that modulates the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:1903059 ! regulation of protein lipidation relationship: regulates GO:0006500 ! N-terminal protein palmitoylation [Term] id: GO:0060262 name: negative regulation of N-terminal protein palmitoylation namespace: biological_process def: "Any process that decreases the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0060254 ! regulation of N-terminal protein palmitoylation is_a: GO:1903060 ! negative regulation of protein lipidation relationship: negatively_regulates GO:0006500 ! N-terminal protein palmitoylation [Term] id: GO:0060300 name: regulation of cytokine activity namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0010469 ! regulation of signaling receptor activity [Term] id: GO:0060302 name: negative regulation of cytokine activity namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0060300 ! regulation of cytokine activity [Term] id: GO:0060314 name: regulation of ryanodine-sensitive calcium-release channel activity namespace: biological_process def: "Any process that modulates the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:1901019 ! regulation of calcium ion transmembrane transporter activity is_a: GO:2001257 ! regulation of cation channel activity [Term] id: GO:0060315 name: negative regulation of ryanodine-sensitive calcium-release channel activity namespace: biological_process def: "Any process that decreases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0060314 ! regulation of ryanodine-sensitive calcium-release channel activity is_a: GO:1901020 ! negative regulation of calcium ion transmembrane transporter activity is_a: GO:2001258 ! negative regulation of cation channel activity [Term] id: GO:0060316 name: positive regulation of ryanodine-sensitive calcium-release channel activity namespace: biological_process def: "Any process that increases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0060314 ! regulation of ryanodine-sensitive calcium-release channel activity is_a: GO:1901021 ! positive regulation of calcium ion transmembrane transporter activity is_a: GO:2001259 ! positive regulation of cation channel activity [Term] id: GO:0060550 name: positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity namespace: biological_process def: "Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0010922 ! positive regulation of phosphatase activity created_by: dph creation_date: 2009-04-13T02:12:33Z [Term] id: GO:0060558 name: regulation of calcidiol 1-monooxygenase activity namespace: biological_process def: "Any process that modulates the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0051341 ! regulation of oxidoreductase activity created_by: dph creation_date: 2009-04-13T02:52:18Z [Term] id: GO:0060559 name: positive regulation of calcidiol 1-monooxygenase activity namespace: biological_process def: "Any process that increases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0032770 ! positive regulation of monooxygenase activity is_a: GO:0060558 ! regulation of calcidiol 1-monooxygenase activity created_by: dph creation_date: 2009-04-13T02:57:28Z [Term] id: GO:0060585 name: positive regulation of prostaglandin-endoperoxide synthase activity namespace: biological_process def: "Any process that increases the rate, frequency or extent of prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "positive regulation of (PG)H synthase activity" RELATED [EC:1.14.99.1] synonym: "positive regulation of fatty acid cyclooxygenase activity" RELATED [EC:1.14.99.1] synonym: "positive regulation of PG synthetase activity" RELATED [EC:1.14.99.1] synonym: "positive regulation of prostaglandin synthetase activity" RELATED [EC:1.14.99.1] is_a: GO:0051353 ! positive regulation of oxidoreductase activity created_by: dph creation_date: 2009-05-08T02:12:34Z [Term] id: GO:0060695 name: negative regulation of cholesterol transporter activity namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of cholesterol transporter activity." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0110114 ! negative regulation of lipid transporter activity created_by: dph creation_date: 2009-06-08T02:08:34Z [Term] id: GO:0060699 name: regulation of endoribonuclease activity namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0060700 ! regulation of ribonuclease activity created_by: dph creation_date: 2009-06-08T02:43:10Z [Term] id: GO:0060700 name: regulation of ribonuclease activity namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0051336 ! regulation of hydrolase activity created_by: dph creation_date: 2009-06-08T02:45:46Z [Term] id: GO:0060702 name: negative regulation of endoribonuclease activity namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0032074 ! negative regulation of nuclease activity is_a: GO:0060699 ! regulation of endoribonuclease activity created_by: dph creation_date: 2009-06-08T02:52:27Z [Term] id: GO:0060725 name: regulation of coreceptor activity namespace: biological_process def: "Any process that modulates the rate or frequency of coreceptor activity, combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0010469 ! regulation of signaling receptor activity created_by: dph creation_date: 2009-06-12T01:20:11Z [Term] id: GO:0060734 name: regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to endoplasmic reticulum stress." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "regulation of eIF2 alpha phosphorylation by endoplasmic reticulum stress" EXACT [] synonym: "regulation of eIF2 alpha phosphorylation by ER stress" EXACT [GOC:dph, GOC:tb] synonym: "regulation of ER stress-induced eIF2 alpha phosphorylation" EXACT [GOC:bf] is_a: GO:0001932 ! regulation of protein phosphorylation relationship: regulates GO:0036492 ! eiF2alpha phosphorylation in response to endoplasmic reticulum stress property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI created_by: dph creation_date: 2009-06-12T02:15:16Z [Term] id: GO:0060735 name: regulation of eIF2 alpha phosphorylation by dsRNA namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to double-stranded RNA." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "regulation of eIF2 alpha phosphorylation by double-stranded RNA" EXACT [GOC:dph] synonym: "regulation of eIF2 alpha phosphorylation by PKR" NARROW [GOC:dph, GOC:tb] is_a: GO:0001932 ! regulation of protein phosphorylation relationship: regulates GO:0010998 ! regulation of translational initiation by eIF2 alpha phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI created_by: dph creation_date: 2009-06-12T02:27:14Z [Term] id: GO:0061097 name: regulation of protein tyrosine kinase activity namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0045859 ! regulation of protein kinase activity is_a: GO:0050730 ! regulation of peptidyl-tyrosine phosphorylation created_by: dph creation_date: 2010-04-26T02:34:53Z [Term] id: GO:0061098 name: positive regulation of protein tyrosine kinase activity namespace: biological_process def: "Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0045860 ! positive regulation of protein kinase activity is_a: GO:0050731 ! positive regulation of peptidyl-tyrosine phosphorylation is_a: GO:0061097 ! regulation of protein tyrosine kinase activity created_by: dph creation_date: 2010-04-26T02:34:53Z [Term] id: GO:0061099 name: negative regulation of protein tyrosine kinase activity namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0006469 ! negative regulation of protein kinase activity is_a: GO:0050732 ! negative regulation of peptidyl-tyrosine phosphorylation is_a: GO:0061097 ! regulation of protein tyrosine kinase activity created_by: dph creation_date: 2010-04-26T02:34:53Z [Term] id: GO:0061365 name: positive regulation of triglyceride lipase activity namespace: biological_process def: "Any process that increases the activity of triglyceride lipase." [GOC:dph] subset: gocheck_obsoletion_candidate synonym: "positive regulation of TAG activity" EXACT [PMID:16054079] is_a: GO:0060193 ! positive regulation of lipase activity created_by: dph creation_date: 2010-10-15T08:27:22Z [Term] id: GO:0061606 name: N-terminal protein amino acid propionylation namespace: biological_process def: "The propionylation of the N-terminal amino acid of proteins." [GOC:dph, PMID:17267393, PMID:23043182] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification created_by: dph creation_date: 2014-02-11T14:13:05Z [Term] id: GO:0061698 name: protein deglutarylation namespace: biological_process def: "The removal of a glutaryl group (CO-CH2-CH2-CH2-CO) from a residue in a peptide or protein." [GOC:dph, PMID:24703693] subset: gocheck_obsoletion_candidate is_a: GO:0035601 ! protein deacylation created_by: dph creation_date: 2015-05-07T11:02:31Z [Term] id: GO:0061739 name: protein lipidation involved in autophagosome assembly namespace: biological_process def: "The protein lipidation process by which phosphatidylethanolamine is conjugated to a protein of the ATG8 family, leading to membrane insertion of the protein as a step in autophagosome assembly." [GOC:autophagy, GOC:dph, PMID:11096062, PMID:11100732, PMID:15277523] subset: gocheck_obsoletion_candidate is_a: GO:0006501 ! C-terminal protein lipidation created_by: dph creation_date: 2015-10-14T12:02:01Z [Term] id: GO:0061907 name: negative regulation of AMPA receptor activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor activity." [GOC:aruk, GOC:bc, PMID:20739563] subset: gocheck_obsoletion_candidate is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity is_a: GO:2000272 ! negative regulation of signaling receptor activity is_a: GO:2000311 ! regulation of AMPA receptor activity created_by: dph creation_date: 2017-06-29T11:55:11Z [Term] id: GO:0061921 name: peptidyl-lysine propionylation namespace: biological_process def: "The propionylation of peptidyl-lysine." [PMID:17267393] subset: gocheck_obsoletion_candidate is_a: GO:0043543 ! protein acylation created_by: dph creation_date: 2017-08-02T13:37:14Z [Term] id: GO:0062003 name: negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity namespace: biological_process def: "Any process that decreases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity." [PMID:23407971] subset: gocheck_obsoletion_candidate is_a: GO:0051346 ! negative regulation of hydrolase activity created_by: dph creation_date: 2018-02-26T13:23:20Z [Term] id: GO:0065009 name: regulation of molecular function namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GOC:isa_complete] subset: gocheck_obsoletion_candidate subset: goslim_pir subset: goslim_plant synonym: "regulation of a molecular function" EXACT [] [Term] id: GO:0070262 name: peptidyl-serine dephosphorylation namespace: biological_process def: "The removal of phosphoric residues from peptidyl-O-phospho-L-serine to form peptidyl-serine." [GOC:bf] subset: gocheck_obsoletion_candidate is_a: GO:0006470 ! protein dephosphorylation [Term] id: GO:0070846 name: Hsp90 deacetylation namespace: biological_process def: "The modification of an Hsp90 protein by removal of acetyl groups." [GOC:BHF, GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0006476 ! protein deacetylation created_by: mah creation_date: 2009-07-31T12:58:47Z [Term] id: GO:0070926 name: regulation of ATP:ADP antiporter activity namespace: biological_process def: "Any process that modulates the activity of an ATP:ADP antiporter." [GOC:BHF, GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0022898 ! regulation of transmembrane transporter activity relationship: regulates GO:0071705 ! nitrogen compound transport created_by: mah creation_date: 2009-09-16T02:56:35Z [Term] id: GO:0071705 name: nitrogen compound transport namespace: biological_process def: "The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] subset: gocheck_obsoletion_candidate created_by: mah creation_date: 2010-03-08T03:56:28Z [Term] id: GO:0071900 name: regulation of protein serine/threonine kinase activity namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of protein serine/threonine kinase activity." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0045859 ! regulation of protein kinase activity created_by: mah creation_date: 2010-09-15T03:08:35Z [Term] id: GO:0071901 name: negative regulation of protein serine/threonine kinase activity namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of protein serine/threonine kinase activity." [GOC:BHF, GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0006469 ! negative regulation of protein kinase activity is_a: GO:0071900 ! regulation of protein serine/threonine kinase activity created_by: mah creation_date: 2010-09-15T03:09:43Z [Term] id: GO:0071902 name: positive regulation of protein serine/threonine kinase activity namespace: biological_process def: "Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity." [GOC:mah] subset: gocheck_obsoletion_candidate is_a: GO:0045860 ! positive regulation of protein kinase activity is_a: GO:0071900 ! regulation of protein serine/threonine kinase activity created_by: mah creation_date: 2010-09-15T03:09:57Z [Term] id: GO:0071929 name: alpha-tubulin acetylation namespace: biological_process def: "The addition of an acetyl group to the lysine 40 residue of alpha-tubulin." [GOC:kmv, PMID:17786050] subset: gocheck_obsoletion_candidate is_a: GO:0018393 ! internal peptidyl-lysine acetylation created_by: mah creation_date: 2010-09-28T01:46:38Z [Term] id: GO:0072580 name: bacterial-type EF-P lysine modification namespace: biological_process def: "The modification of a lysine residue in a protein to produce (2S)-2-amino-6-([(3S)-3,6-diaminohexanoyl]amino)hexanoic acid, and the subsequent hydroxylation of the modified lysine residue. This modification is observed in, and is probably unique to, the prokaryotic translation elongation factor P (EF-P)." [GOC:curators, GOC:imk, GOC:mah, PMID:20729861, PMID:22706199, RESID:AA0530, RESID:AA0531] comment: The EF-P modification pathway is now thought to be composed of three steps: conversion of alpha-lysyl-EF-P to beta-lysyl-EF-P, lysylation of Lys34, and hydroxylation of Lys34. subset: gocheck_obsoletion_candidate synonym: "EF-P modification pathway" EXACT [PMID:22706199] is_a: GO:0018205 ! peptidyl-lysine modification created_by: mah creation_date: 2011-02-07T11:47:33Z [Term] id: GO:0080058 name: protein deglutathionylation namespace: biological_process def: "The protein modification process in which a glutathione molecule is removed from a protein amino acid by breaking a disulfide linkage." [GOC:tb] subset: gocheck_obsoletion_candidate synonym: "protein amino acid deglutathionylation" EXACT [GOC:bf] is_a: GO:0043412 ! macromolecule modification created_by: dhl creation_date: 2009-04-13T02:48:06Z [Term] id: GO:0090042 name: tubulin deacetylation namespace: biological_process def: "The removal of an acetyl group from tubulin. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0006476 ! protein deacetylation created_by: tb creation_date: 2009-08-03T11:50:47Z [Term] id: GO:0090043 name: regulation of tubulin deacetylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0090311 ! regulation of protein deacetylation relationship: regulates GO:0090042 ! tubulin deacetylation created_by: tb creation_date: 2009-08-03T11:53:07Z [Term] id: GO:0090044 name: positive regulation of tubulin deacetylation namespace: biological_process def: "Any process that increases the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0090043 ! regulation of tubulin deacetylation is_a: GO:0090312 ! positive regulation of protein deacetylation relationship: positively_regulates GO:0090042 ! tubulin deacetylation created_by: tb creation_date: 2009-08-03T11:54:18Z [Term] id: GO:0090045 name: positive regulation of deacetylase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of deacetylase activity, the catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule." [GOC:BHF, GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0043085 ! positive regulation of catalytic activity is_a: GO:0150065 ! regulation of deacetylase activity created_by: tb creation_date: 2009-08-03T12:00:14Z [Term] id: GO:0090074 name: negative regulation of protein homodimerization activity namespace: biological_process def: "Any process that decreases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0043496 ! regulation of protein homodimerization activity created_by: tb creation_date: 2009-09-11T11:15:40Z [Term] id: GO:0090218 name: positive regulation of lipid kinase activity namespace: biological_process def: "Any process that increases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid." [GOC:dph, GOC:tb] subset: gocheck_obsoletion_candidate is_a: GO:0033674 ! positive regulation of kinase activity is_a: GO:0043550 ! regulation of lipid kinase activity created_by: tb creation_date: 2010-01-12T10:18:30Z [Term] id: GO:0090311 name: regulation of protein deacetylation namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid." [GOC:tb] subset: gocheck_obsoletion_candidate synonym: "regulation of protein amino acid deacetylation" EXACT [GOC:bf] relationship: regulates GO:0006476 ! protein deacetylation created_by: tb creation_date: 2010-04-14T01:30:45Z [Term] id: GO:0090312 name: positive regulation of protein deacetylation namespace: biological_process def: "Any process that increases the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid." [GOC:ecd, PMID:20027304] subset: gocheck_obsoletion_candidate synonym: "positive regulation of protein amino acid deacetylation" EXACT [GOC:bf] is_a: GO:0031401 ! positive regulation of protein modification process is_a: GO:0090311 ! regulation of protein deacetylation relationship: positively_regulates GO:0006476 ! protein deacetylation created_by: tb creation_date: 2010-04-14T01:30:45Z [Term] id: GO:0090630 name: activation of GTPase activity namespace: biological_process alt_id: GO:0032856 alt_id: GO:0032857 alt_id: GO:0032858 alt_id: GO:0032859 alt_id: GO:0032860 alt_id: GO:0032861 alt_id: GO:0032862 alt_id: GO:0032863 alt_id: GO:0032864 def: "Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP." [GOC:dph, GOC:mah, GOC:tb] subset: gocheck_obsoletion_candidate synonym: "activation of ARF GTPase activity" NARROW [] synonym: "activation of Cdc42 GTPase activity" NARROW [] synonym: "activation of Rab GTPase activity" NARROW [] synonym: "activation of Rac GTPase activity" NARROW [] synonym: "activation of Ral GTPase activity" NARROW [] synonym: "activation of Ran GTPase activity" NARROW [] synonym: "activation of Rap GTPase activity" NARROW [] synonym: "activation of Ras GTPase activity" NARROW [] synonym: "activation of Rho GTPase activity" NARROW [] synonym: "ARF GTPase activation" NARROW [] synonym: "Cdc42 GTPase activation" NARROW [] synonym: "Rab GTPase activation" NARROW [] synonym: "Rac GTPase activation" NARROW [] synonym: "Ral GTPase activation" NARROW [] synonym: "Ran GTPase activation" NARROW [] synonym: "Rap GTPase activation" NARROW [] synonym: "Ras GTPase activation" NARROW [] synonym: "Rho GTPase activation" NARROW [] is_a: GO:0043547 ! positive regulation of GTPase activity created_by: tb creation_date: 2015-02-11T16:09:19Z [Term] id: GO:0097502 name: mannosylation namespace: biological_process def: "The covalent attachment of a mannose residue to a substrate molecule." [GOC:cjm] subset: gocheck_obsoletion_candidate created_by: pr creation_date: 2013-09-20T09:47:40Z [Term] id: GO:0098628 name: peptidyl-N-phospho-arginine dephosphorylation namespace: biological_process def: "The removal of phosphate residues from peptidyl-N-phospho-arginine to form peptidyl-arginine." [PMID:23770242] subset: gocheck_obsoletion_candidate is_a: GO:0006470 ! protein dephosphorylation created_by: dos creation_date: 2014-04-17T18:03:31Z [Term] id: GO:0098962 name: regulation of postsynaptic neurotransmitter receptor activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity involved in synaptic transmission. Modulation may be via an effect on ligand affinity, or effector function such as ion selectivity or pore opening/closing in ionotropic receptors." [GOC:dos] subset: gocheck_obsoletion_candidate subset: goslim_synapse is_a: GO:0099601 ! regulation of neurotransmitter receptor activity [Term] id: GO:0099531 name: presynaptic process involved in chemical synaptic transmission namespace: biological_process def: "The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission." [GOC:dos] subset: gocheck_obsoletion_candidate subset: goslim_synapse [Term] id: GO:0099601 name: regulation of neurotransmitter receptor activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector function such as ion selectivity or pore opening/closing in ionotropic receptors." [GOC:dos] subset: gocheck_obsoletion_candidate subset: goslim_synapse is_a: GO:0010469 ! regulation of signaling receptor activity [Term] id: GO:0106040 name: regulation of GABA-A receptor activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of GABA-A receptor activity." [PMID:24044036] subset: gocheck_obsoletion_candidate is_a: GO:0010469 ! regulation of signaling receptor activity created_by: hjd creation_date: 2017-07-27T18:47:02Z [Term] id: GO:0106227 name: peptidyl-lysine glutarylation namespace: biological_process def: "The glutarylation of a lysine residue in a protein." [GOC:sp, PMID:31542297] subset: gocheck_obsoletion_candidate is_a: GO:0043543 ! protein acylation created_by: hjd creation_date: 2019-10-17T18:57:19Z [Term] id: GO:0106230 name: protein depropionylation namespace: biological_process def: "The removal of a propionyl group from a residue in a peptide or protein." [GOC:sp, PMID:30026585] subset: gocheck_obsoletion_candidate is_a: GO:0035601 ! protein deacylation created_by: hjd creation_date: 2019-10-17T19:10:50Z [Term] id: GO:0110113 name: positive regulation of lipid transporter activity namespace: biological_process def: "Any process that increases the frequency, rate, or extent of lipid transporter activity." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27365390] subset: gocheck_obsoletion_candidate is_a: GO:0032411 ! positive regulation of transporter activity created_by: kmv creation_date: 2018-07-06T19:14:13Z [Term] id: GO:0110114 name: negative regulation of lipid transporter activity namespace: biological_process def: "Any process that decreases the frequency, rate, or extent of lipid transporter activity." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27365390] subset: gocheck_obsoletion_candidate is_a: GO:0032410 ! negative regulation of transporter activity created_by: kmv creation_date: 2018-07-06T19:21:44Z [Term] id: GO:0120093 name: regulation of peptidyl-lysine crotonylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of crotonylation of a lysine residue in a protein." [PMID:28803779] subset: gocheck_obsoletion_candidate relationship: regulates GO:0140066 ! peptidyl-lysine crotonylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/14109" xsd:anyURI created_by: krc creation_date: 2017-08-22T20:25:51Z [Term] id: GO:0120094 name: negative regulation of peptidyl-lysine crotonylation namespace: biological_process def: "Any process that stops or reduces the rate of crotonylation of a lysine residue in a protein." [PMID:28803779] subset: gocheck_obsoletion_candidate is_a: GO:0031400 ! negative regulation of protein modification process is_a: GO:0120093 ! regulation of peptidyl-lysine crotonylation relationship: negatively_regulates GO:0140066 ! peptidyl-lysine crotonylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/14109" xsd:anyURI created_by: krc creation_date: 2017-08-22T20:36:36Z [Term] id: GO:0120257 name: peptidyl-threonine acetylation namespace: biological_process def: "The acetylation of peptidyl-threonine." [GOC:krc, PMID:16728640, PMID:22802624] subset: gocheck_obsoletion_candidate is_a: GO:0006473 ! protein acetylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19957" xsd:anyURI created_by: krc creation_date: 2020-09-08T18:01:01Z [Term] id: GO:0120258 name: peptidyl-threonine O-acetylation namespace: biological_process def: "The acetylation of peptidyl-threonine to form peptidyl-O-acetyl-L-threonine." [PMID:16728640, PMID:22802624, RESID:AA0423] subset: gocheck_obsoletion_candidate xref: RESID:AA0364 is_a: GO:0018210 ! peptidyl-threonine modification is_a: GO:0120257 ! peptidyl-threonine acetylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19957" xsd:anyURI created_by: krc creation_date: 2020-09-08T18:07:44Z [Term] id: GO:0140066 name: peptidyl-lysine crotonylation namespace: biological_process def: "The crotonylation of a lysine residue in a protein. Crotonyl is the univalent radical CH3-CH=CH-CO- derived from crotonic acid." [PMID:25818647, Wikipedia:crotonyl] subset: gocheck_obsoletion_candidate is_a: GO:0043543 ! protein acylation created_by: pg creation_date: 2017-07-20T16:48:58Z [Term] id: GO:0140067 name: peptidyl-lysine butyrylation namespace: biological_process def: "The butyrylation of a lysine residue in a protein. Butyryl is the univalent radical C3H7COO- derived from butyric acid." [PMID:27105113, Wikipedia:butyryl] subset: gocheck_obsoletion_candidate is_a: GO:0043543 ! protein acylation created_by: pg creation_date: 2017-07-20T16:52:19Z [Term] id: GO:0140438 name: protein stearoylation namespace: biological_process def: "The covalent attachment of a stearoyl group to an amino acid in a protein." [PMID:26214738] subset: gocheck_obsoletion_candidate is_a: GO:0006497 ! protein lipidation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18882" xsd:anyURI created_by: pg creation_date: 2020-03-11T07:54:48Z [Term] id: GO:0150065 name: regulation of deacetylase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of deacetylase activity." [GOC:aruk, GOC:bc, PMID:19457097] subset: gocheck_obsoletion_candidate is_a: GO:0050790 ! regulation of catalytic activity created_by: bc creation_date: 2018-07-23T12:24:28Z [Term] id: GO:0150072 name: positive regulation of arginase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of arginase activity." [GOC:aruk, GOC:bc, PMID:26670206] subset: gocheck_obsoletion_candidate is_a: GO:0051345 ! positive regulation of hydrolase activity created_by: bc creation_date: 2018-07-25T09:26:20Z [Term] id: GO:0150074 name: positive regulation of protein-glutamine gamma-glutamyltransferase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity." [GOC:aruk, GOC:bc, PMID:26670206] subset: gocheck_obsoletion_candidate is_a: GO:0051347 ! positive regulation of transferase activity created_by: bc creation_date: 2018-07-25T10:08:19Z [Term] id: GO:1900003 name: regulation of serine-type endopeptidase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of serine-type endopeptidase activity." [GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "regulation of blood coagulation factor activity" RELATED [GOC:TermGenie] is_a: GO:0052548 ! regulation of endopeptidase activity created_by: kmv creation_date: 2012-01-09T10:03:15Z [Term] id: GO:1900004 name: negative regulation of serine-type endopeptidase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of serine-type endopeptidase activity." [GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "down regulation of blood coagulation factor activity" RELATED [GOC:TermGenie] synonym: "down regulation of serine-type endopeptidase activity" RELATED [GOC:TermGenie] synonym: "negative regulation of blood coagulation factor activity" RELATED [GOC:TermGenie] is_a: GO:0010951 ! negative regulation of endopeptidase activity is_a: GO:1900003 ! regulation of serine-type endopeptidase activity is_a: GO:1902572 ! negative regulation of serine-type peptidase activity created_by: kmv creation_date: 2012-01-09T10:03:20Z [Term] id: GO:1900005 name: positive regulation of serine-type endopeptidase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of serine-type endopeptidase activity." [GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "positive regulation of blood coagulation factor activity" RELATED [GOC:TermGenie] synonym: "up regulation of blood coagulation factor activity" RELATED [GOC:TermGenie] synonym: "up regulation of serine-type endopeptidase activity" RELATED [GOC:TermGenie] is_a: GO:0010950 ! positive regulation of endopeptidase activity is_a: GO:1900003 ! regulation of serine-type endopeptidase activity created_by: kmv creation_date: 2012-01-09T10:03:29Z [Term] id: GO:1900011 name: negative regulation of corticotropin-releasing hormone receptor activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of corticotropin-releasing hormone receptor activity." [GOC:TermGenie, GOC:yaf, PMID:18234674] subset: gocheck_obsoletion_candidate synonym: "down regulation of adrenocorticotropin-releasing hormone receptor activity" EXACT [GOC:TermGenie] synonym: "down regulation of corticotropin-releasing factor receptor activity" EXACT [GOC:TermGenie] synonym: "down regulation of corticotropin-releasing hormone receptor activity" RELATED [GOC:TermGenie] synonym: "down regulation of CRF receptor activity" EXACT [GOC:TermGenie] synonym: "down regulation of CRH receptor activity" EXACT [GOC:TermGenie] synonym: "negative regulation of adrenocorticotropin-releasing hormone receptor activity" EXACT [GOC:TermGenie] synonym: "negative regulation of corticotropin-releasing factor receptor activity" EXACT [GOC:TermGenie] synonym: "negative regulation of CRF receptor activity" EXACT [GOC:TermGenie] synonym: "negative regulation of CRH receptor activity" EXACT [GOC:TermGenie] is_a: GO:2000272 ! negative regulation of signaling receptor activity created_by: pr creation_date: 2012-01-10T02:27:27Z [Term] id: GO:1900019 name: regulation of protein kinase C activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein kinase C activity." [GOC:signaling, GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "regulation of PKC" RELATED [GOC:TermGenie] synonym: "regulation of PKC activity" EXACT [GOC:TermGenie] is_a: GO:0071900 ! regulation of protein serine/threonine kinase activity created_by: bf creation_date: 2012-01-11T03:50:47Z [Term] id: GO:1900020 name: positive regulation of protein kinase C activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein kinase C activity." [GOC:signaling, GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "positive regulation of PKC" RELATED [GOC:TermGenie] synonym: "positive regulation of PKC activity" EXACT [GOC:TermGenie] synonym: "up regulation of PKC" RELATED [GOC:TermGenie] synonym: "up regulation of PKC activity" EXACT [GOC:TermGenie] is_a: GO:0071902 ! positive regulation of protein serine/threonine kinase activity is_a: GO:1900019 ! regulation of protein kinase C activity created_by: bf creation_date: 2012-01-11T03:50:55Z [Term] id: GO:1900084 name: regulation of peptidyl-tyrosine autophosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of peptidyl-tyrosine autophosphorylation." [GOC:bf, GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "regulation of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] synonym: "regulation of tyrosine autophosphorylation" EXACT [GOC:TermGenie] is_a: GO:0031952 ! regulation of protein autophosphorylation is_a: GO:0050730 ! regulation of peptidyl-tyrosine phosphorylation relationship: regulates GO:0038083 ! peptidyl-tyrosine autophosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI created_by: bf creation_date: 2012-02-03T10:17:07Z [Term] id: GO:1900085 name: negative regulation of peptidyl-tyrosine autophosphorylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-tyrosine autophosphorylation." [GOC:bf, GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "down regulation of peptidyl-tyrosine autophosphorylation" EXACT [GOC:TermGenie] synonym: "down regulation of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] synonym: "down regulation of tyrosine autophosphorylation" EXACT [GOC:TermGenie] synonym: "down-regulation of peptidyl-tyrosine autophosphorylation" EXACT [GOC:TermGenie] synonym: "down-regulation of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] synonym: "down-regulation of tyrosine autophosphorylation" EXACT [GOC:TermGenie] synonym: "downregulation of peptidyl-tyrosine autophosphorylation" EXACT [GOC:TermGenie] synonym: "downregulation of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] synonym: "downregulation of tyrosine autophosphorylation" EXACT [GOC:TermGenie] synonym: "inhibition of peptidyl-tyrosine autophosphorylation" NARROW [GOC:TermGenie] synonym: "inhibition of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] synonym: "inhibition of tyrosine autophosphorylation" NARROW [GOC:TermGenie] synonym: "negative regulation of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] synonym: "negative regulation of tyrosine autophosphorylation" EXACT [GOC:TermGenie] is_a: GO:0031953 ! negative regulation of protein autophosphorylation is_a: GO:0050732 ! negative regulation of peptidyl-tyrosine phosphorylation is_a: GO:1900084 ! regulation of peptidyl-tyrosine autophosphorylation relationship: negatively_regulates GO:0038083 ! peptidyl-tyrosine autophosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI created_by: bf creation_date: 2012-02-03T10:17:12Z [Term] id: GO:1900086 name: positive regulation of peptidyl-tyrosine autophosphorylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of peptidyl-tyrosine autophosphorylation." [GOC:bf, GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "activation of peptidyl-tyrosine autophosphorylation" NARROW [GOC:TermGenie] synonym: "activation of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] synonym: "activation of tyrosine autophosphorylation" NARROW [GOC:TermGenie] synonym: "positive regulation of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] synonym: "positive regulation of tyrosine autophosphorylation" EXACT [GOC:TermGenie] synonym: "up regulation of peptidyl-tyrosine autophosphorylation" EXACT [GOC:TermGenie] synonym: "up regulation of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] synonym: "up regulation of tyrosine autophosphorylation" EXACT [GOC:TermGenie] synonym: "up-regulation of peptidyl-tyrosine autophosphorylation" EXACT [GOC:TermGenie] synonym: "up-regulation of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] synonym: "up-regulation of tyrosine autophosphorylation" EXACT [GOC:TermGenie] synonym: "upregulation of peptidyl-tyrosine autophosphorylation" EXACT [GOC:TermGenie] synonym: "upregulation of receptor tyrosine kinase autophosphorylation" NARROW [GOC:TermGenie] synonym: "upregulation of tyrosine autophosphorylation" EXACT [GOC:TermGenie] is_a: GO:0031954 ! positive regulation of protein autophosphorylation is_a: GO:0050731 ! positive regulation of peptidyl-tyrosine phosphorylation is_a: GO:1900084 ! regulation of peptidyl-tyrosine autophosphorylation relationship: positively_regulates GO:0038083 ! peptidyl-tyrosine autophosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI created_by: bf creation_date: 2012-02-03T10:17:15Z [Term] id: GO:1900128 name: regulation of G-protein activated inward rectifier potassium channel activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity." [GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "regulation of G protein activated inward rectifier potassium channel activity" EXACT [GOC:TermGenie] synonym: "regulation of G protein enhanced inward rectifier potassium channel activity" EXACT [GOC:TermGenie] synonym: "regulation of G-protein enhanced inward rectifier potassium channel activity" EXACT [GOC:TermGenie] synonym: "regulation of G-protein-activated inward rectifier potassium channel activity" EXACT [GOC:TermGenie] synonym: "regulation of G-protein-enhanced inward rectifier potassium channel activity" EXACT [GOC:TermGenie] is_a: GO:1901979 ! regulation of inward rectifier potassium channel activity created_by: bf creation_date: 2012-02-23T03:12:53Z [Term] id: GO:1900136 name: regulation of chemokine activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of chemokine activity." [GOC:TermGenie] subset: gocheck_obsoletion_candidate is_a: GO:0060300 ! regulation of cytokine activity created_by: bf creation_date: 2012-02-28T01:36:29Z [Term] id: GO:1900137 name: negative regulation of chemokine activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of chemokine activity." [GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "down regulation of chemokine activity" EXACT [GOC:TermGenie] synonym: "down-regulation of chemokine activity" EXACT [GOC:TermGenie] synonym: "downregulation of chemokine activity" EXACT [GOC:TermGenie] synonym: "inhibition of chemokine activity" NARROW [GOC:TermGenie] is_a: GO:0060302 ! negative regulation of cytokine activity is_a: GO:1900136 ! regulation of chemokine activity created_by: bf creation_date: 2012-02-28T01:36:33Z [Term] id: GO:1900138 name: negative regulation of phospholipase A2 activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase A2 activity." [GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "down regulation of cytosolic phospholipase A2 activity" NARROW [GOC:TermGenie] synonym: "down regulation of lecithinase A activity" EXACT [GOC:TermGenie] synonym: "down regulation of phosphatidase activity" RELATED [GOC:TermGenie] synonym: "down regulation of phosphatidolipase activity" EXACT [GOC:TermGenie] synonym: "down regulation of phosphatidylcholine 2-acylhydrolase activity" EXACT [GOC:TermGenie] synonym: "down regulation of phospholipase A" RELATED [GOC:TermGenie] synonym: "down regulation of phospholipase A2 activity" EXACT [GOC:TermGenie] synonym: "down regulation of secreted phospholipase A2 activity" NARROW [GOC:TermGenie] synonym: "down-regulation of cytosolic phospholipase A2 activity" NARROW [GOC:TermGenie] synonym: "down-regulation of lecithinase A activity" EXACT [GOC:TermGenie] synonym: "down-regulation of phosphatidase activity" RELATED [GOC:TermGenie] synonym: "down-regulation of phosphatidolipase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of phosphatidylcholine 2-acylhydrolase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of phospholipase A" RELATED [GOC:TermGenie] synonym: "down-regulation of phospholipase A2 activity" EXACT [GOC:TermGenie] synonym: "down-regulation of secreted phospholipase A2 activity" NARROW [GOC:TermGenie] synonym: "downregulation of cytosolic phospholipase A2 activity" NARROW [GOC:TermGenie] synonym: "downregulation of lecithinase A activity" EXACT [GOC:TermGenie] synonym: "downregulation of phosphatidase activity" RELATED [GOC:TermGenie] synonym: "downregulation of phosphatidolipase activity" EXACT [GOC:TermGenie] synonym: "downregulation of phosphatidylcholine 2-acylhydrolase activity" EXACT [GOC:TermGenie] synonym: "downregulation of phospholipase A" RELATED [GOC:TermGenie] synonym: "downregulation of phospholipase A2 activity" EXACT [GOC:TermGenie] synonym: "downregulation of secreted phospholipase A2 activity" NARROW [GOC:TermGenie] synonym: "inhibition of cytosolic phospholipase A2 activity" NARROW [GOC:TermGenie] synonym: "inhibition of lecithinase A activity" NARROW [GOC:TermGenie] synonym: "inhibition of phosphatidase activity" RELATED [GOC:TermGenie] synonym: "inhibition of phosphatidolipase activity" NARROW [GOC:TermGenie] synonym: "inhibition of phosphatidylcholine 2-acylhydrolase activity" NARROW [GOC:TermGenie] synonym: "inhibition of phospholipase A" RELATED [GOC:TermGenie] synonym: "inhibition of phospholipase A2 activity" NARROW [GOC:TermGenie] synonym: "inhibition of secreted phospholipase A2 activity" NARROW [GOC:TermGenie] synonym: "negative regulation of cytosolic phospholipase A2 activity" NARROW [GOC:TermGenie] synonym: "negative regulation of lecithinase A activity" EXACT [GOC:TermGenie] synonym: "negative regulation of phosphatidase activity" RELATED [GOC:TermGenie] synonym: "negative regulation of phosphatidolipase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of phosphatidylcholine 2-acylhydrolase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of phospholipase A" RELATED [GOC:TermGenie] synonym: "negative regulation of secreted phospholipase A2 activity" NARROW [GOC:TermGenie] is_a: GO:0010519 ! negative regulation of phospholipase activity is_a: GO:0032429 ! regulation of phospholipase A2 activity created_by: rph creation_date: 2012-03-01T09:18:24Z [Term] id: GO:1900163 name: positive regulation of phospholipid scramblase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of phospholipid scramblase activity." [GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "activation of phospholipid scramblase activity" NARROW [GOC:TermGenie] synonym: "up regulation of phospholipid scramblase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of phospholipid scramblase activity" EXACT [GOC:TermGenie] synonym: "upregulation of phospholipid scramblase activity" EXACT [GOC:TermGenie] is_a: GO:0110113 ! positive regulation of lipid transporter activity created_by: rph creation_date: 2012-03-08T10:57:26Z [Term] id: GO:1900260 name: negative regulation of RNA-dependent RNA polymerase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity." [GOC:pf, GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "down regulation of PB1 proteins" RELATED [GOC:TermGenie] synonym: "down regulation of PB2 proteins" RELATED [GOC:TermGenie] synonym: "down regulation of phage f2 replicase" NARROW [GOC:TermGenie] synonym: "down regulation of polymerase L" RELATED [GOC:TermGenie] synonym: "down regulation of RDRP" RELATED [GOC:TermGenie] synonym: "down regulation of ribonucleic acid replicase activity" EXACT [GOC:TermGenie] synonym: "down regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] synonym: "down regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity" EXACT [GOC:TermGenie] synonym: "down regulation of ribonucleic replicase activity" EXACT [GOC:TermGenie] synonym: "down regulation of ribonucleic synthetase activity" RELATED [GOC:TermGenie] synonym: "down regulation of RNA nucleotidyltransferase (RNA-directed) activity" EXACT [GOC:TermGenie] synonym: "down regulation of RNA replicase activity" EXACT [GOC:TermGenie] synonym: "down regulation of RNA synthetase activity" RELATED [GOC:TermGenie] synonym: "down regulation of RNA-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] synonym: "down regulation of RNA-dependent RNA polymerase activity" EXACT [GOC:TermGenie] synonym: "down regulation of RNA-dependent RNA replicase activity" EXACT [GOC:TermGenie] synonym: "down regulation of RNA-directed RNA polymerase activity" EXACT [GOC:TermGenie] synonym: "down regulation of transcriptase" BROAD [GOC:TermGenie] synonym: "down-regulation of PB1 proteins" RELATED [GOC:TermGenie] synonym: "down-regulation of PB2 proteins" RELATED [GOC:TermGenie] synonym: "down-regulation of phage f2 replicase" NARROW [GOC:TermGenie] synonym: "down-regulation of polymerase L" RELATED [GOC:TermGenie] synonym: "down-regulation of RDRP" RELATED [GOC:TermGenie] synonym: "down-regulation of ribonucleic acid replicase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of ribonucleic synthetase activity" RELATED [GOC:TermGenie] synonym: "down-regulation of RNA nucleotidyltransferase (RNA-directed) activity" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA replicase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA synthetase activity" RELATED [GOC:TermGenie] synonym: "down-regulation of RNA-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA-dependent RNA polymerase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA-dependent RNA replicase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA-directed RNA polymerase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of transcriptase" BROAD [GOC:TermGenie] synonym: "downregulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)" EXACT [GOC:TermGenie] synonym: "downregulation of PB1 proteins" RELATED [GOC:TermGenie] synonym: "downregulation of PB2 proteins" RELATED [GOC:TermGenie] synonym: "downregulation of phage f2 replicase" NARROW [GOC:TermGenie] synonym: "downregulation of polymerase L" RELATED [GOC:TermGenie] synonym: "downregulation of RDRP" RELATED [GOC:TermGenie] synonym: "downregulation of ribonucleic acid replicase activity" EXACT [GOC:TermGenie] synonym: "downregulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] synonym: "downregulation of ribonucleic acid-dependent ribonucleic acid polymerase activity" EXACT [GOC:TermGenie] synonym: "downregulation of ribonucleic replicase activity" EXACT [GOC:TermGenie] synonym: "downregulation of ribonucleic synthetase activity" RELATED [GOC:TermGenie] synonym: "downregulation of RNA nucleotidyltransferase (RNA-directed) activity" EXACT [GOC:TermGenie] synonym: "downregulation of RNA replicase activity" EXACT [GOC:TermGenie] synonym: "downregulation of RNA synthetase activity" RELATED [GOC:TermGenie] synonym: "downregulation of RNA-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] synonym: "downregulation of RNA-dependent RNA polymerase activity" EXACT [GOC:TermGenie] synonym: "downregulation of RNA-dependent RNA replicase activity" EXACT [GOC:TermGenie] synonym: "downregulation of RNA-directed RNA polymerase activity" EXACT [GOC:TermGenie] synonym: "downregulation of transcriptase" BROAD [GOC:TermGenie] synonym: "inhibition of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)" EXACT [GOC:TermGenie] synonym: "inhibition of PB1 proteins" RELATED [GOC:TermGenie] synonym: "inhibition of PB2 proteins" RELATED [GOC:TermGenie] synonym: "inhibition of phage f2 replicase" NARROW [GOC:TermGenie] synonym: "inhibition of polymerase L" RELATED [GOC:TermGenie] synonym: "inhibition of RDRP" RELATED [GOC:TermGenie] synonym: "inhibition of ribonucleic acid replicase activity" EXACT [GOC:TermGenie] synonym: "inhibition of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] synonym: "inhibition of ribonucleic acid-dependent ribonucleic acid polymerase activity" EXACT [GOC:TermGenie] synonym: "inhibition of ribonucleic replicase activity" EXACT [GOC:TermGenie] synonym: "inhibition of ribonucleic synthetase activity" RELATED [GOC:TermGenie] synonym: "inhibition of RNA nucleotidyltransferase (RNA-directed) activity" EXACT [GOC:TermGenie] synonym: "inhibition of RNA replicase activity" EXACT [GOC:TermGenie] synonym: "inhibition of RNA synthetase activity" RELATED [GOC:TermGenie] synonym: "inhibition of RNA-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] synonym: "inhibition of RNA-dependent RNA polymerase activity" EXACT [GOC:TermGenie] synonym: "inhibition of RNA-dependent RNA replicase activity" EXACT [GOC:TermGenie] synonym: "inhibition of RNA-directed RNA polymerase activity" NARROW [GOC:TermGenie] synonym: "inhibition of transcriptase" BROAD [GOC:TermGenie] synonym: "negative regulation of 3D polymerase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)" EXACT [GOC:TermGenie] synonym: "negative regulation of PB1 proteins" RELATED [GOC:TermGenie] synonym: "negative regulation of PB2 proteins" RELATED [GOC:TermGenie] synonym: "negative regulation of phage f2 replicase" NARROW [GOC:TermGenie] synonym: "negative regulation of polymerase L" RELATED [GOC:TermGenie] synonym: "negative regulation of RDRP" RELATED [GOC:TermGenie] synonym: "negative regulation of ribonucleic acid replicase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of ribonucleic replicase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of ribonucleic synthetase activity" RELATED [GOC:TermGenie] synonym: "negative regulation of RNA nucleotidyltransferase (RNA-directed) activity" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA replicase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA synthetase activity" RELATED [GOC:TermGenie] synonym: "negative regulation of RNA-dependent ribonucleate nucleotidyltransferase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA-dependent RNA replicase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA-directed 5'-3' RNA polymerase activity" EXACT [] synonym: "negative regulation of RNA-directed RNA polymerase activity" BROAD [] synonym: "negative regulation of transcriptase" BROAD [GOC:TermGenie] is_a: GO:0051348 ! negative regulation of transferase activity created_by: tb creation_date: 2012-04-03T11:02:03Z [Term] id: GO:1900264 name: positive regulation of DNA-directed DNA polymerase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of DNA-directed DNA polymerase activity." [GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "activation of alpha DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "activation of beta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "activation of delta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "activation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] synonym: "activation of deoxyribonucleic acid duplicase activity" EXACT [GOC:TermGenie] synonym: "activation of deoxyribonucleic duplicase activity" EXACT [GOC:TermGenie] synonym: "activation of deoxyribonucleic polymerase I" NARROW [GOC:TermGenie] synonym: "activation of DNA duplicase activity" EXACT [GOC:TermGenie] synonym: "activation of DNA nucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] synonym: "activation of DNA polymerase alpha" NARROW [GOC:TermGenie] synonym: "activation of DNA polymerase beta" NARROW [GOC:TermGenie] synonym: "activation of DNA polymerase gamma" NARROW [GOC:TermGenie] synonym: "activation of DNA polymerase I" NARROW [GOC:TermGenie] synonym: "activation of DNA polymerase II" NARROW [GOC:TermGenie] synonym: "activation of DNA polymerase III" NARROW [GOC:TermGenie] synonym: "activation of DNA polymerase V activity" NARROW [GOC:TermGenie] synonym: "activation of DNA replicase activity" EXACT [GOC:TermGenie] synonym: "activation of DNA-dependent DNA polymerase activity" EXACT [GOC:TermGenie] synonym: "activation of DNA-directed DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "activation of duplicase" BROAD [GOC:TermGenie] synonym: "activation of epsilon DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "activation of eta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "activation of gamma DNA-directed DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "activation of iota DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "activation of kappa DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "activation of Klenow fragment" NARROW [GOC:TermGenie] synonym: "activation of lambda DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "activation of mu DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "activation of nu DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "activation of sequenase" RELATED [GOC:TermGenie] synonym: "activation of sigma DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "activation of Taq DNA polymerase" NARROW [GOC:TermGenie] synonym: "activation of Taq Pol I" NARROW [GOC:TermGenie] synonym: "activation of Tca DNA polymerase" NARROW [GOC:TermGenie] synonym: "activation of theta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "activation of zeta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of alpha DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of beta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of delta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] synonym: "positive regulation of deoxyribonucleic acid duplicase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of deoxyribonucleic duplicase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of deoxyribonucleic polymerase I" NARROW [GOC:TermGenie] synonym: "positive regulation of DNA duplicase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of DNA nucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] synonym: "positive regulation of DNA polymerase alpha" NARROW [GOC:TermGenie] synonym: "positive regulation of DNA polymerase beta" NARROW [GOC:TermGenie] synonym: "positive regulation of DNA polymerase gamma" NARROW [GOC:TermGenie] synonym: "positive regulation of DNA polymerase I" NARROW [GOC:TermGenie] synonym: "positive regulation of DNA polymerase II" NARROW [GOC:TermGenie] synonym: "positive regulation of DNA polymerase III" NARROW [GOC:TermGenie] synonym: "positive regulation of DNA polymerase V activity" NARROW [GOC:TermGenie] synonym: "positive regulation of DNA replicase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of DNA-dependent DNA polymerase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of duplicase" BROAD [GOC:TermGenie] synonym: "positive regulation of epsilon DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of eta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of gamma DNA-directed DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of iota DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of kappa DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of Klenow fragment" NARROW [GOC:TermGenie] synonym: "positive regulation of lambda DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of mu DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of nu DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of sequenase" RELATED [GOC:TermGenie] synonym: "positive regulation of sigma DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of Taq DNA polymerase" NARROW [GOC:TermGenie] synonym: "positive regulation of Taq Pol I" NARROW [GOC:TermGenie] synonym: "positive regulation of Tca DNA polymerase" NARROW [GOC:TermGenie] synonym: "positive regulation of theta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of zeta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up regulation of alpha DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up regulation of beta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up regulation of delta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] synonym: "up regulation of deoxyribonucleic acid duplicase activity" EXACT [GOC:TermGenie] synonym: "up regulation of deoxyribonucleic duplicase activity" EXACT [GOC:TermGenie] synonym: "up regulation of deoxyribonucleic polymerase I" NARROW [GOC:TermGenie] synonym: "up regulation of DNA duplicase activity" EXACT [GOC:TermGenie] synonym: "up regulation of DNA nucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] synonym: "up regulation of DNA polymerase alpha" NARROW [GOC:TermGenie] synonym: "up regulation of DNA polymerase beta" NARROW [GOC:TermGenie] synonym: "up regulation of DNA polymerase gamma" NARROW [GOC:TermGenie] synonym: "up regulation of DNA polymerase I" NARROW [GOC:TermGenie] synonym: "up regulation of DNA polymerase II" NARROW [GOC:TermGenie] synonym: "up regulation of DNA polymerase III" NARROW [GOC:TermGenie] synonym: "up regulation of DNA polymerase V activity" NARROW [GOC:TermGenie] synonym: "up regulation of DNA replicase activity" EXACT [GOC:TermGenie] synonym: "up regulation of DNA-dependent DNA polymerase activity" EXACT [GOC:TermGenie] synonym: "up regulation of DNA-directed DNA polymerase activity" EXACT [GOC:TermGenie] synonym: "up regulation of duplicase" BROAD [GOC:TermGenie] synonym: "up regulation of epsilon DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up regulation of eta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up regulation of gamma DNA-directed DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up regulation of iota DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up regulation of kappa DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up regulation of Klenow fragment" NARROW [GOC:TermGenie] synonym: "up regulation of lambda DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up regulation of mu DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up regulation of nu DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up regulation of sequenase" RELATED [GOC:TermGenie] synonym: "up regulation of sigma DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up regulation of Taq DNA polymerase" NARROW [GOC:TermGenie] synonym: "up regulation of Taq Pol I" NARROW [GOC:TermGenie] synonym: "up regulation of Tca DNA polymerase" NARROW [GOC:TermGenie] synonym: "up regulation of theta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up regulation of zeta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of alpha DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of beta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of delta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] synonym: "up-regulation of deoxyribonucleic acid duplicase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of deoxyribonucleic duplicase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of deoxyribonucleic polymerase I" NARROW [GOC:TermGenie] synonym: "up-regulation of DNA duplicase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA nucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA polymerase alpha" NARROW [GOC:TermGenie] synonym: "up-regulation of DNA polymerase beta" NARROW [GOC:TermGenie] synonym: "up-regulation of DNA polymerase gamma" NARROW [GOC:TermGenie] synonym: "up-regulation of DNA polymerase I" NARROW [GOC:TermGenie] synonym: "up-regulation of DNA polymerase II" NARROW [GOC:TermGenie] synonym: "up-regulation of DNA polymerase III" NARROW [GOC:TermGenie] synonym: "up-regulation of DNA polymerase V activity" NARROW [GOC:TermGenie] synonym: "up-regulation of DNA replicase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA-dependent DNA polymerase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA-directed DNA polymerase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of duplicase" BROAD [GOC:TermGenie] synonym: "up-regulation of epsilon DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of eta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of gamma DNA-directed DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of iota DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of kappa DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of Klenow fragment" NARROW [GOC:TermGenie] synonym: "up-regulation of lambda DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of mu DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of nu DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of sequenase" RELATED [GOC:TermGenie] synonym: "up-regulation of sigma DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of Taq DNA polymerase" NARROW [GOC:TermGenie] synonym: "up-regulation of Taq Pol I" NARROW [GOC:TermGenie] synonym: "up-regulation of Tca DNA polymerase" NARROW [GOC:TermGenie] synonym: "up-regulation of theta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of zeta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "upregulation of alpha DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "upregulation of beta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "upregulation of delta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "upregulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] synonym: "upregulation of deoxyribonucleic acid duplicase activity" EXACT [GOC:TermGenie] synonym: "upregulation of deoxyribonucleic duplicase activity" EXACT [GOC:TermGenie] synonym: "upregulation of deoxyribonucleic polymerase I" NARROW [GOC:TermGenie] synonym: "upregulation of DNA duplicase activity" EXACT [GOC:TermGenie] synonym: "upregulation of DNA nucleotidyltransferase (DNA-directed) activity" EXACT [GOC:TermGenie] synonym: "upregulation of DNA polymerase alpha" NARROW [GOC:TermGenie] synonym: "upregulation of DNA polymerase beta" NARROW [GOC:TermGenie] synonym: "upregulation of DNA polymerase gamma" NARROW [GOC:TermGenie] synonym: "upregulation of DNA polymerase I" NARROW [GOC:TermGenie] synonym: "upregulation of DNA polymerase II" NARROW [GOC:TermGenie] synonym: "upregulation of DNA polymerase III" NARROW [GOC:TermGenie] synonym: "upregulation of DNA polymerase V activity" NARROW [GOC:TermGenie] synonym: "upregulation of DNA replicase activity" EXACT [GOC:TermGenie] synonym: "upregulation of DNA-dependent DNA polymerase activity" EXACT [GOC:TermGenie] synonym: "upregulation of DNA-directed DNA polymerase activity" EXACT [GOC:TermGenie] synonym: "upregulation of duplicase" BROAD [GOC:TermGenie] synonym: "upregulation of epsilon DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "upregulation of eta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "upregulation of gamma DNA-directed DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "upregulation of iota DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "upregulation of kappa DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "upregulation of Klenow fragment" NARROW [GOC:TermGenie] synonym: "upregulation of lambda DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "upregulation of mu DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "upregulation of nu DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "upregulation of sequenase" RELATED [GOC:TermGenie] synonym: "upregulation of sigma DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "upregulation of Taq DNA polymerase" NARROW [GOC:TermGenie] synonym: "upregulation of Taq Pol I" NARROW [GOC:TermGenie] synonym: "upregulation of Tca DNA polymerase" NARROW [GOC:TermGenie] synonym: "upregulation of theta DNA polymerase activity" NARROW [GOC:TermGenie] synonym: "upregulation of zeta DNA polymerase activity" NARROW [GOC:TermGenie] is_a: GO:0051347 ! positive regulation of transferase activity created_by: tb creation_date: 2012-04-03T11:07:27Z [Term] id: GO:1900722 name: regulation of protein adenylylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein adenylylation." [GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "regulation of protein adenylation" EXACT [GOC:TermGenie] synonym: "regulation of protein amino acid adenylylation" EXACT [GOC:TermGenie] synonym: "regulation of protein AMPylation" EXACT [GOC:TermGenie] relationship: regulates GO:0018117 ! protein adenylylation created_by: jl creation_date: 2012-05-24T03:15:44Z [Term] id: GO:1900723 name: negative regulation of protein adenylylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein adenylylation." [GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "down regulation of protein adenylation" EXACT [GOC:TermGenie] synonym: "down regulation of protein adenylylation" EXACT [GOC:TermGenie] synonym: "down regulation of protein amino acid adenylylation" EXACT [GOC:TermGenie] synonym: "down regulation of protein AMPylation" EXACT [GOC:TermGenie] synonym: "down-regulation of protein adenylation" EXACT [GOC:TermGenie] synonym: "down-regulation of protein adenylylation" EXACT [GOC:TermGenie] synonym: "down-regulation of protein amino acid adenylylation" EXACT [GOC:TermGenie] synonym: "down-regulation of protein AMPylation" EXACT [GOC:TermGenie] synonym: "downregulation of protein adenylation" EXACT [GOC:TermGenie] synonym: "downregulation of protein adenylylation" EXACT [GOC:TermGenie] synonym: "downregulation of protein amino acid adenylylation" EXACT [GOC:TermGenie] synonym: "downregulation of protein AMPylation" EXACT [GOC:TermGenie] synonym: "inhibition of protein adenylation" EXACT [GOC:TermGenie] synonym: "inhibition of protein adenylylation" NARROW [GOC:TermGenie] synonym: "inhibition of protein amino acid adenylylation" EXACT [GOC:TermGenie] synonym: "inhibition of protein AMPylation" EXACT [GOC:TermGenie] synonym: "negative regulation of protein adenylation" EXACT [GOC:TermGenie] synonym: "negative regulation of protein amino acid adenylylation" EXACT [GOC:TermGenie] synonym: "negative regulation of protein AMPylation" EXACT [GOC:TermGenie] is_a: GO:0031400 ! negative regulation of protein modification process is_a: GO:1900722 ! regulation of protein adenylylation relationship: negatively_regulates GO:0018117 ! protein adenylylation created_by: jl creation_date: 2012-05-24T03:16:06Z [Term] id: GO:1900724 name: positive regulation of protein adenylylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein adenylylation." [GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "activation of protein adenylation" EXACT [GOC:TermGenie] synonym: "activation of protein adenylylation" NARROW [GOC:TermGenie] synonym: "activation of protein amino acid adenylylation" EXACT [GOC:TermGenie] synonym: "activation of protein AMPylation" EXACT [GOC:TermGenie] synonym: "positive regulation of protein adenylation" EXACT [GOC:TermGenie] synonym: "positive regulation of protein amino acid adenylylation" EXACT [GOC:TermGenie] synonym: "positive regulation of protein AMPylation" EXACT [GOC:TermGenie] synonym: "up regulation of protein adenylation" EXACT [GOC:TermGenie] synonym: "up regulation of protein adenylylation" EXACT [GOC:TermGenie] synonym: "up regulation of protein amino acid adenylylation" EXACT [GOC:TermGenie] synonym: "up regulation of protein AMPylation" EXACT [GOC:TermGenie] synonym: "up-regulation of protein adenylation" EXACT [GOC:TermGenie] synonym: "up-regulation of protein adenylylation" EXACT [GOC:TermGenie] synonym: "up-regulation of protein amino acid adenylylation" EXACT [GOC:TermGenie] synonym: "up-regulation of protein AMPylation" EXACT [GOC:TermGenie] synonym: "upregulation of protein adenylation" EXACT [GOC:TermGenie] synonym: "upregulation of protein adenylylation" EXACT [GOC:TermGenie] synonym: "upregulation of protein amino acid adenylylation" EXACT [GOC:TermGenie] synonym: "upregulation of protein AMPylation" EXACT [GOC:TermGenie] is_a: GO:0031401 ! positive regulation of protein modification process is_a: GO:1900722 ! regulation of protein adenylylation relationship: positively_regulates GO:0018117 ! protein adenylylation created_by: jl creation_date: 2012-05-24T03:16:13Z [Term] id: GO:1901016 name: regulation of potassium ion transmembrane transporter activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of potassium ion transmembrane transporter activity." [GOC:BHF, GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "regulation of potassium transporter activity" EXACT [GOC:TermGenie] is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity created_by: rl creation_date: 2012-06-15T01:13:49Z [Term] id: GO:1901017 name: negative regulation of potassium ion transmembrane transporter activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transporter activity." [GOC:BHF, GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "down regulation of potassium ion transmembrane transporter activity" EXACT [GOC:TermGenie] synonym: "down regulation of potassium transporter activity" EXACT [GOC:TermGenie] synonym: "down-regulation of potassium ion transmembrane transporter activity" EXACT [GOC:TermGenie] synonym: "down-regulation of potassium transporter activity" EXACT [GOC:TermGenie] synonym: "downregulation of potassium ion transmembrane transporter activity" EXACT [GOC:TermGenie] synonym: "downregulation of potassium transporter activity" EXACT [GOC:TermGenie] synonym: "inhibition of potassium ion transmembrane transporter activity" NARROW [GOC:TermGenie] synonym: "inhibition of potassium transporter activity" EXACT [GOC:TermGenie] synonym: "negative regulation of potassium transporter activity" EXACT [GOC:TermGenie] is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity is_a: GO:1901016 ! regulation of potassium ion transmembrane transporter activity created_by: rl creation_date: 2012-06-15T01:14:10Z [Term] id: GO:1901018 name: positive regulation of potassium ion transmembrane transporter activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transporter activity." [GOC:BHF, GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "activation of potassium ion transmembrane transporter activity" NARROW [GOC:TermGenie] synonym: "activation of potassium transporter activity" EXACT [GOC:TermGenie] synonym: "positive regulation of potassium transporter activity" EXACT [GOC:TermGenie] synonym: "up regulation of potassium ion transmembrane transporter activity" EXACT [GOC:TermGenie] synonym: "up regulation of potassium transporter activity" EXACT [GOC:TermGenie] synonym: "up-regulation of potassium ion transmembrane transporter activity" EXACT [GOC:TermGenie] synonym: "up-regulation of potassium transporter activity" EXACT [GOC:TermGenie] synonym: "upregulation of potassium ion transmembrane transporter activity" EXACT [GOC:TermGenie] synonym: "upregulation of potassium transporter activity" EXACT [GOC:TermGenie] is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity is_a: GO:1901016 ! regulation of potassium ion transmembrane transporter activity created_by: rl creation_date: 2012-06-15T01:14:18Z [Term] id: GO:1901019 name: regulation of calcium ion transmembrane transporter activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of calcium ion transmembrane transporter activity." [GOC:BHF, GOC:TermGenie] subset: gocheck_obsoletion_candidate is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity created_by: rl creation_date: 2012-06-15T07:54:12Z [Term] id: GO:1901020 name: negative regulation of calcium ion transmembrane transporter activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transporter activity." [GOC:BHF, GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "down regulation of calcium ion transmembrane transporter activity" EXACT [GOC:TermGenie] synonym: "down-regulation of calcium ion transmembrane transporter activity" EXACT [GOC:TermGenie] synonym: "downregulation of calcium ion transmembrane transporter activity" EXACT [GOC:TermGenie] synonym: "inhibition of calcium ion transmembrane transporter activity" NARROW [GOC:TermGenie] is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity is_a: GO:1901019 ! regulation of calcium ion transmembrane transporter activity created_by: rl creation_date: 2012-06-15T07:54:32Z [Term] id: GO:1901021 name: positive regulation of calcium ion transmembrane transporter activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transporter activity." [GOC:BHF, GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "activation of calcium ion transmembrane transporter activity" NARROW [GOC:TermGenie] synonym: "up regulation of calcium ion transmembrane transporter activity" EXACT [GOC:TermGenie] synonym: "up-regulation of calcium ion transmembrane transporter activity" EXACT [GOC:TermGenie] synonym: "upregulation of calcium ion transmembrane transporter activity" EXACT [GOC:TermGenie] is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity is_a: GO:1901019 ! regulation of calcium ion transmembrane transporter activity created_by: rl creation_date: 2012-06-15T07:54:40Z [Term] id: GO:1901339 name: regulation of store-operated calcium channel activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of store-operated calcium channel activity." [GOC:TermGenie] subset: gocheck_obsoletion_candidate is_a: GO:1901019 ! regulation of calcium ion transmembrane transporter activity is_a: GO:2001257 ! regulation of cation channel activity created_by: pr creation_date: 2012-09-03T14:23:10Z [Term] id: GO:1901340 name: negative regulation of store-operated calcium channel activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium channel activity." [GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "down regulation of store-operated calcium channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of store-operated calcium channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of store-operated calcium channel activity" EXACT [GOC:TermGenie] synonym: "inhibition of store-operated calcium channel activity" NARROW [GOC:TermGenie] is_a: GO:1901020 ! negative regulation of calcium ion transmembrane transporter activity is_a: GO:1901339 ! regulation of store-operated calcium channel activity is_a: GO:2001258 ! negative regulation of cation channel activity created_by: pr creation_date: 2012-09-03T14:24:21Z [Term] id: GO:1901341 name: positive regulation of store-operated calcium channel activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of store-operated calcium channel activity." [GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "activation of store-operated calcium channel activity" NARROW [GOC:TermGenie] synonym: "up regulation of store-operated calcium channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of store-operated calcium channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of store-operated calcium channel activity" EXACT [GOC:TermGenie] is_a: GO:1901021 ! positive regulation of calcium ion transmembrane transporter activity is_a: GO:1901339 ! regulation of store-operated calcium channel activity is_a: GO:2001259 ! positive regulation of cation channel activity created_by: pr creation_date: 2012-09-03T14:24:38Z [Term] id: GO:1901385 name: regulation of voltage-gated calcium channel activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of voltage-gated calcium channel activity." [GOC:BHF, GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "regulation of depolarization-activated calcium channel" BROAD [GOC:TermGenie] synonym: "regulation of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "regulation of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] synonym: "regulation of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "regulation of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] synonym: "regulation of voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "regulation of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] synonym: "regulation of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] synonym: "regulation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] is_a: GO:1901019 ! regulation of calcium ion transmembrane transporter activity is_a: GO:2001257 ! regulation of cation channel activity created_by: vk creation_date: 2012-10-01T10:34:08Z [Term] id: GO:1901386 name: negative regulation of voltage-gated calcium channel activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity." [GOC:BHF, GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "down regulation of depolarization-activated calcium channel" BROAD [GOC:TermGenie] synonym: "down regulation of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "down regulation of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] synonym: "down regulation of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "down regulation of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] synonym: "down regulation of voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "down regulation of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] synonym: "down regulation of voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "down regulation of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] synonym: "down regulation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] synonym: "down-regulation of depolarization-activated calcium channel" BROAD [GOC:TermGenie] synonym: "down-regulation of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] synonym: "down-regulation of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] synonym: "down-regulation of voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] synonym: "downregulation of depolarization-activated calcium channel" BROAD [GOC:TermGenie] synonym: "downregulation of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] synonym: "downregulation of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] synonym: "downregulation of voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] synonym: "inhibition of depolarization-activated calcium channel" BROAD [GOC:TermGenie] synonym: "inhibition of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "inhibition of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] synonym: "inhibition of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "inhibition of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] synonym: "inhibition of voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "inhibition of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] synonym: "inhibition of voltage-gated calcium channel activity" NARROW [GOC:TermGenie] synonym: "inhibition of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] synonym: "inhibition of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] synonym: "negative regulation of depolarization-activated calcium channel" BROAD [GOC:TermGenie] synonym: "negative regulation of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "negative regulation of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] synonym: "negative regulation of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "negative regulation of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] synonym: "negative regulation of voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "negative regulation of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] synonym: "negative regulation of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] synonym: "negative regulation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] is_a: GO:1901020 ! negative regulation of calcium ion transmembrane transporter activity is_a: GO:1901385 ! regulation of voltage-gated calcium channel activity is_a: GO:2001258 ! negative regulation of cation channel activity created_by: vk creation_date: 2012-10-01T10:35:15Z [Term] id: GO:1901387 name: positive regulation of voltage-gated calcium channel activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of voltage-gated calcium channel activity." [GOC:BHF, GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "activation of depolarization-activated calcium channel" BROAD [GOC:TermGenie] synonym: "activation of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "activation of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] synonym: "activation of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "activation of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] synonym: "activation of voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "activation of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] synonym: "activation of voltage-gated calcium channel activity" NARROW [GOC:TermGenie] synonym: "activation of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] synonym: "activation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] synonym: "positive regulation of depolarization-activated calcium channel" BROAD [GOC:TermGenie] synonym: "positive regulation of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "positive regulation of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] synonym: "positive regulation of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "positive regulation of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] synonym: "positive regulation of voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "positive regulation of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] synonym: "positive regulation of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] synonym: "positive regulation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] synonym: "up regulation of depolarization-activated calcium channel" BROAD [GOC:TermGenie] synonym: "up regulation of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] synonym: "up regulation of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] synonym: "up regulation of voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] synonym: "up-regulation of depolarization-activated calcium channel" BROAD [GOC:TermGenie] synonym: "up-regulation of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] synonym: "up-regulation of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] synonym: "up-regulation of voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] synonym: "upregulation of depolarization-activated calcium channel" BROAD [GOC:TermGenie] synonym: "upregulation of depolarization-activated voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of depolarization-activated voltage-gated calcium channel" EXACT [GOC:TermGenie] synonym: "upregulation of depolarization-activated voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of dihydropyridine-sensitive calcium channel activity" NARROW [GOC:TermGenie] synonym: "upregulation of voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of voltage-gated calcium ion channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of voltage-sensitive calcium channel" EXACT [GOC:TermGenie] is_a: GO:1901021 ! positive regulation of calcium ion transmembrane transporter activity is_a: GO:1901385 ! regulation of voltage-gated calcium channel activity is_a: GO:2001259 ! positive regulation of cation channel activity created_by: vk creation_date: 2012-10-01T10:35:32Z [Term] id: GO:1901529 name: positive regulation of anion channel activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of anion channel activity." [GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "activation of anion channel activity" NARROW [GOC:TermGenie] synonym: "up regulation of anion channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of anion channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of anion channel activity" EXACT [GOC:TermGenie] is_a: GO:0010359 ! regulation of anion channel activity is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity created_by: tb creation_date: 2012-10-23T23:38:50Z [Term] id: GO:1901666 name: positive regulation of NAD+ ADP-ribosyltransferase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity." [GOC:BHF, GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "activation of ADP-ribosyltransferase (polymerizing) activity" EXACT [GOC:TermGenie] synonym: "activation of NAD ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] synonym: "activation of NAD+ ADP-ribosyltransferase activity" NARROW [GOC:TermGenie] synonym: "activation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity" EXACT [GOC:TermGenie] synonym: "activation of poly(adenosine diphosphate ribose) polymerase activity" EXACT [GOC:TermGenie] synonym: "activation of poly(ADP-ribose) synthase activity" EXACT [GOC:TermGenie] synonym: "activation of poly(ADP-ribose) synthetase activity" EXACT [GOC:TermGenie] synonym: "activation of poly(ADP-ribose)polymerase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of ADP-ribosyltransferase (polymerizing) activity" EXACT [GOC:TermGenie] synonym: "positive regulation of NAD ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of poly(adenosine diphosphate ribose) polymerase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of poly(ADP-ribose) synthase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of poly(ADP-ribose) synthetase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of poly(ADP-ribose)polymerase activity" EXACT [GOC:TermGenie] synonym: "up regulation of ADP-ribosyltransferase (polymerizing) activity" EXACT [GOC:TermGenie] synonym: "up regulation of NAD ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] synonym: "up regulation of NAD+ ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] synonym: "up regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity" EXACT [GOC:TermGenie] synonym: "up regulation of poly(adenosine diphosphate ribose) polymerase activity" EXACT [GOC:TermGenie] synonym: "up regulation of poly(ADP-ribose) synthase activity" EXACT [GOC:TermGenie] synonym: "up regulation of poly(ADP-ribose) synthetase activity" EXACT [GOC:TermGenie] synonym: "up regulation of poly(ADP-ribose)polymerase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of ADP-ribosyltransferase (polymerizing) activity" EXACT [GOC:TermGenie] synonym: "up-regulation of NAD ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of NAD+ ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of poly(adenosine diphosphate ribose) polymerase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of poly(ADP-ribose) synthase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of poly(ADP-ribose) synthetase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of poly(ADP-ribose)polymerase activity" EXACT [GOC:TermGenie] synonym: "upregulation of ADP-ribosyltransferase (polymerizing) activity" EXACT [GOC:TermGenie] synonym: "upregulation of NAD ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] synonym: "upregulation of NAD+ ADP-ribosyltransferase activity" EXACT [GOC:TermGenie] synonym: "upregulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity" EXACT [GOC:TermGenie] synonym: "upregulation of poly(adenosine diphosphate ribose) polymerase activity" EXACT [GOC:TermGenie] synonym: "upregulation of poly(ADP-ribose) synthase activity" EXACT [GOC:TermGenie] synonym: "upregulation of poly(ADP-ribose) synthetase activity" EXACT [GOC:TermGenie] synonym: "upregulation of poly(ADP-ribose)polymerase activity" EXACT [GOC:TermGenie] is_a: GO:0051347 ! positive regulation of transferase activity created_by: vk creation_date: 2012-11-20T18:50:20Z [Term] id: GO:1901668 name: regulation of superoxide dismutase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of superoxide dismutase activity." [GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "regulation of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "regulation of Cu,Zn-SOD" RELATED [GOC:TermGenie] synonym: "regulation of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "regulation of cuprein" RELATED [GOC:TermGenie] synonym: "regulation of cytocuprein" RELATED [GOC:TermGenie] synonym: "regulation of erythrocuprein" RELATED [GOC:TermGenie] synonym: "regulation of Fe-SOD" RELATED [GOC:TermGenie] synonym: "regulation of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "regulation of hemocuprein" RELATED [GOC:TermGenie] synonym: "regulation of hepatocuprein" RELATED [GOC:TermGenie] synonym: "regulation of iron superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "regulation of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "regulation of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "regulation of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "regulation of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] synonym: "regulation of Mn-SOD" RELATED [GOC:TermGenie] synonym: "regulation of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "regulation of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "regulation of SOD" RELATED [GOC:TermGenie] synonym: "regulation of SOD-1" RELATED [GOC:TermGenie] synonym: "regulation of SOD-2" RELATED [GOC:TermGenie] synonym: "regulation of SOD-3" RELATED [GOC:TermGenie] synonym: "regulation of SOD-4" RELATED [GOC:TermGenie] synonym: "regulation of SODF" RELATED [GOC:TermGenie] synonym: "regulation of SODS" RELATED [GOC:TermGenie] synonym: "regulation of superoxide dismutase I" RELATED [GOC:TermGenie] synonym: "regulation of superoxide dismutase II" RELATED [GOC:TermGenie] synonym: "regulation of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "regulation of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] is_a: GO:0051341 ! regulation of oxidoreductase activity created_by: tb creation_date: 2012-11-21T20:46:42Z [Term] id: GO:1901670 name: negative regulation of superoxide dismutase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of superoxide dismutase activity." [GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "down regulation of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "down regulation of Cu,Zn-SOD" RELATED [GOC:TermGenie] synonym: "down regulation of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "down regulation of cuprein" RELATED [GOC:TermGenie] synonym: "down regulation of cytocuprein" RELATED [GOC:TermGenie] synonym: "down regulation of erythrocuprein" RELATED [GOC:TermGenie] synonym: "down regulation of Fe-SOD" RELATED [GOC:TermGenie] synonym: "down regulation of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "down regulation of hemocuprein" RELATED [GOC:TermGenie] synonym: "down regulation of hepatocuprein" RELATED [GOC:TermGenie] synonym: "down regulation of iron superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "down regulation of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "down regulation of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "down regulation of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "down regulation of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] synonym: "down regulation of Mn-SOD" RELATED [GOC:TermGenie] synonym: "down regulation of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "down regulation of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "down regulation of SOD" RELATED [GOC:TermGenie] synonym: "down regulation of SOD-1" RELATED [GOC:TermGenie] synonym: "down regulation of SOD-2" RELATED [GOC:TermGenie] synonym: "down regulation of SOD-3" RELATED [GOC:TermGenie] synonym: "down regulation of SOD-4" RELATED [GOC:TermGenie] synonym: "down regulation of SODF" RELATED [GOC:TermGenie] synonym: "down regulation of SODS" RELATED [GOC:TermGenie] synonym: "down regulation of superoxide dismutase activity" EXACT [GOC:TermGenie] synonym: "down regulation of superoxide dismutase I" RELATED [GOC:TermGenie] synonym: "down regulation of superoxide dismutase II" RELATED [GOC:TermGenie] synonym: "down regulation of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "down regulation of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "down-regulation of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "down-regulation of Cu,Zn-SOD" RELATED [GOC:TermGenie] synonym: "down-regulation of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "down-regulation of cuprein" RELATED [GOC:TermGenie] synonym: "down-regulation of cytocuprein" RELATED [GOC:TermGenie] synonym: "down-regulation of erythrocuprein" RELATED [GOC:TermGenie] synonym: "down-regulation of Fe-SOD" RELATED [GOC:TermGenie] synonym: "down-regulation of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "down-regulation of hemocuprein" RELATED [GOC:TermGenie] synonym: "down-regulation of hepatocuprein" RELATED [GOC:TermGenie] synonym: "down-regulation of iron superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "down-regulation of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "down-regulation of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "down-regulation of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "down-regulation of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] synonym: "down-regulation of Mn-SOD" RELATED [GOC:TermGenie] synonym: "down-regulation of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "down-regulation of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "down-regulation of SOD" RELATED [GOC:TermGenie] synonym: "down-regulation of SOD-1" RELATED [GOC:TermGenie] synonym: "down-regulation of SOD-2" RELATED [GOC:TermGenie] synonym: "down-regulation of SOD-3" RELATED [GOC:TermGenie] synonym: "down-regulation of SOD-4" RELATED [GOC:TermGenie] synonym: "down-regulation of SODF" RELATED [GOC:TermGenie] synonym: "down-regulation of SODS" RELATED [GOC:TermGenie] synonym: "down-regulation of superoxide dismutase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of superoxide dismutase I" RELATED [GOC:TermGenie] synonym: "down-regulation of superoxide dismutase II" RELATED [GOC:TermGenie] synonym: "down-regulation of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "downregulation of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "downregulation of Cu,Zn-SOD" RELATED [GOC:TermGenie] synonym: "downregulation of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "downregulation of cuprein" RELATED [GOC:TermGenie] synonym: "downregulation of cytocuprein" RELATED [GOC:TermGenie] synonym: "downregulation of erythrocuprein" RELATED [GOC:TermGenie] synonym: "downregulation of Fe-SOD" RELATED [GOC:TermGenie] synonym: "downregulation of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "downregulation of hemocuprein" RELATED [GOC:TermGenie] synonym: "downregulation of hepatocuprein" RELATED [GOC:TermGenie] synonym: "downregulation of iron superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "downregulation of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "downregulation of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "downregulation of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "downregulation of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] synonym: "downregulation of Mn-SOD" RELATED [GOC:TermGenie] synonym: "downregulation of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "downregulation of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "downregulation of SOD" RELATED [GOC:TermGenie] synonym: "downregulation of SOD-1" RELATED [GOC:TermGenie] synonym: "downregulation of SOD-2" RELATED [GOC:TermGenie] synonym: "downregulation of SOD-3" RELATED [GOC:TermGenie] synonym: "downregulation of SOD-4" RELATED [GOC:TermGenie] synonym: "downregulation of SODF" RELATED [GOC:TermGenie] synonym: "downregulation of SODS" RELATED [GOC:TermGenie] synonym: "downregulation of superoxide dismutase activity" EXACT [GOC:TermGenie] synonym: "downregulation of superoxide dismutase I" RELATED [GOC:TermGenie] synonym: "downregulation of superoxide dismutase II" RELATED [GOC:TermGenie] synonym: "downregulation of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "downregulation of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "inhibition of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "inhibition of Cu,Zn-SOD" RELATED [GOC:TermGenie] synonym: "inhibition of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "inhibition of cuprein" RELATED [GOC:TermGenie] synonym: "inhibition of cytocuprein" RELATED [GOC:TermGenie] synonym: "inhibition of erythrocuprein" RELATED [GOC:TermGenie] synonym: "inhibition of Fe-SOD" RELATED [GOC:TermGenie] synonym: "inhibition of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "inhibition of hemocuprein" RELATED [GOC:TermGenie] synonym: "inhibition of hepatocuprein" RELATED [GOC:TermGenie] synonym: "inhibition of iron superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "inhibition of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "inhibition of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "inhibition of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "inhibition of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] synonym: "inhibition of Mn-SOD" RELATED [GOC:TermGenie] synonym: "inhibition of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "inhibition of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "inhibition of SOD" RELATED [GOC:TermGenie] synonym: "inhibition of SOD-1" RELATED [GOC:TermGenie] synonym: "inhibition of SOD-2" RELATED [GOC:TermGenie] synonym: "inhibition of SOD-3" RELATED [GOC:TermGenie] synonym: "inhibition of SOD-4" RELATED [GOC:TermGenie] synonym: "inhibition of SODF" RELATED [GOC:TermGenie] synonym: "inhibition of SODS" RELATED [GOC:TermGenie] synonym: "inhibition of superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "inhibition of superoxide dismutase I" RELATED [GOC:TermGenie] synonym: "inhibition of superoxide dismutase II" RELATED [GOC:TermGenie] synonym: "inhibition of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "inhibition of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "negative regulation of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of Cu,Zn-SOD" RELATED [GOC:TermGenie] synonym: "negative regulation of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of cuprein" RELATED [GOC:TermGenie] synonym: "negative regulation of cytocuprein" RELATED [GOC:TermGenie] synonym: "negative regulation of erythrocuprein" RELATED [GOC:TermGenie] synonym: "negative regulation of Fe-SOD" RELATED [GOC:TermGenie] synonym: "negative regulation of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of hemocuprein" RELATED [GOC:TermGenie] synonym: "negative regulation of hepatocuprein" RELATED [GOC:TermGenie] synonym: "negative regulation of iron superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "negative regulation of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "negative regulation of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] synonym: "negative regulation of Mn-SOD" RELATED [GOC:TermGenie] synonym: "negative regulation of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "negative regulation of SOD" RELATED [GOC:TermGenie] synonym: "negative regulation of SOD-1" RELATED [GOC:TermGenie] synonym: "negative regulation of SOD-2" RELATED [GOC:TermGenie] synonym: "negative regulation of SOD-3" RELATED [GOC:TermGenie] synonym: "negative regulation of SOD-4" RELATED [GOC:TermGenie] synonym: "negative regulation of SODF" RELATED [GOC:TermGenie] synonym: "negative regulation of SODS" RELATED [GOC:TermGenie] synonym: "negative regulation of superoxide dismutase I" RELATED [GOC:TermGenie] synonym: "negative regulation of superoxide dismutase II" RELATED [GOC:TermGenie] synonym: "negative regulation of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] is_a: GO:0051354 ! negative regulation of oxidoreductase activity is_a: GO:1901668 ! regulation of superoxide dismutase activity created_by: tb creation_date: 2012-11-21T21:36:07Z [Term] id: GO:1901671 name: positive regulation of superoxide dismutase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of superoxide dismutase activity." [GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "activation of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "activation of Cu,Zn-SOD" RELATED [GOC:TermGenie] synonym: "activation of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "activation of cuprein" RELATED [GOC:TermGenie] synonym: "activation of cytocuprein" RELATED [GOC:TermGenie] synonym: "activation of erythrocuprein" RELATED [GOC:TermGenie] synonym: "activation of Fe-SOD" RELATED [GOC:TermGenie] synonym: "activation of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "activation of hemocuprein" RELATED [GOC:TermGenie] synonym: "activation of hepatocuprein" RELATED [GOC:TermGenie] synonym: "activation of iron superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "activation of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "activation of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "activation of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "activation of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] synonym: "activation of Mn-SOD" RELATED [GOC:TermGenie] synonym: "activation of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "activation of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "activation of SOD" RELATED [GOC:TermGenie] synonym: "activation of SOD-1" RELATED [GOC:TermGenie] synonym: "activation of SOD-2" RELATED [GOC:TermGenie] synonym: "activation of SOD-3" RELATED [GOC:TermGenie] synonym: "activation of SOD-4" RELATED [GOC:TermGenie] synonym: "activation of SODF" RELATED [GOC:TermGenie] synonym: "activation of SODS" RELATED [GOC:TermGenie] synonym: "activation of superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "activation of superoxide dismutase I" RELATED [GOC:TermGenie] synonym: "activation of superoxide dismutase II" RELATED [GOC:TermGenie] synonym: "activation of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "activation of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "positive regulation of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of Cu,Zn-SOD" RELATED [GOC:TermGenie] synonym: "positive regulation of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of cuprein" RELATED [GOC:TermGenie] synonym: "positive regulation of cytocuprein" RELATED [GOC:TermGenie] synonym: "positive regulation of erythrocuprein" RELATED [GOC:TermGenie] synonym: "positive regulation of Fe-SOD" RELATED [GOC:TermGenie] synonym: "positive regulation of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of hemocuprein" RELATED [GOC:TermGenie] synonym: "positive regulation of hepatocuprein" RELATED [GOC:TermGenie] synonym: "positive regulation of iron superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "positive regulation of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "positive regulation of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] synonym: "positive regulation of Mn-SOD" RELATED [GOC:TermGenie] synonym: "positive regulation of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "positive regulation of SOD" RELATED [GOC:TermGenie] synonym: "positive regulation of SOD-1" RELATED [GOC:TermGenie] synonym: "positive regulation of SOD-2" RELATED [GOC:TermGenie] synonym: "positive regulation of SOD-3" RELATED [GOC:TermGenie] synonym: "positive regulation of SOD-4" RELATED [GOC:TermGenie] synonym: "positive regulation of SODF" RELATED [GOC:TermGenie] synonym: "positive regulation of SODS" RELATED [GOC:TermGenie] synonym: "positive regulation of superoxide dismutase I" RELATED [GOC:TermGenie] synonym: "positive regulation of superoxide dismutase II" RELATED [GOC:TermGenie] synonym: "positive regulation of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "up regulation of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "up regulation of Cu,Zn-SOD" RELATED [GOC:TermGenie] synonym: "up regulation of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "up regulation of cuprein" RELATED [GOC:TermGenie] synonym: "up regulation of cytocuprein" RELATED [GOC:TermGenie] synonym: "up regulation of erythrocuprein" RELATED [GOC:TermGenie] synonym: "up regulation of Fe-SOD" RELATED [GOC:TermGenie] synonym: "up regulation of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "up regulation of hemocuprein" RELATED [GOC:TermGenie] synonym: "up regulation of hepatocuprein" RELATED [GOC:TermGenie] synonym: "up regulation of iron superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "up regulation of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "up regulation of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "up regulation of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "up regulation of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] synonym: "up regulation of Mn-SOD" RELATED [GOC:TermGenie] synonym: "up regulation of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "up regulation of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "up regulation of SOD" RELATED [GOC:TermGenie] synonym: "up regulation of SOD-1" RELATED [GOC:TermGenie] synonym: "up regulation of SOD-2" RELATED [GOC:TermGenie] synonym: "up regulation of SOD-3" RELATED [GOC:TermGenie] synonym: "up regulation of SOD-4" RELATED [GOC:TermGenie] synonym: "up regulation of SODF" RELATED [GOC:TermGenie] synonym: "up regulation of SODS" RELATED [GOC:TermGenie] synonym: "up regulation of superoxide dismutase activity" EXACT [GOC:TermGenie] synonym: "up regulation of superoxide dismutase I" RELATED [GOC:TermGenie] synonym: "up regulation of superoxide dismutase II" RELATED [GOC:TermGenie] synonym: "up regulation of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "up regulation of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "up-regulation of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of Cu,Zn-SOD" RELATED [GOC:TermGenie] synonym: "up-regulation of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of cuprein" RELATED [GOC:TermGenie] synonym: "up-regulation of cytocuprein" RELATED [GOC:TermGenie] synonym: "up-regulation of erythrocuprein" RELATED [GOC:TermGenie] synonym: "up-regulation of Fe-SOD" RELATED [GOC:TermGenie] synonym: "up-regulation of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of hemocuprein" RELATED [GOC:TermGenie] synonym: "up-regulation of hepatocuprein" RELATED [GOC:TermGenie] synonym: "up-regulation of iron superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "up-regulation of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "up-regulation of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] synonym: "up-regulation of Mn-SOD" RELATED [GOC:TermGenie] synonym: "up-regulation of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "up-regulation of SOD" RELATED [GOC:TermGenie] synonym: "up-regulation of SOD-1" RELATED [GOC:TermGenie] synonym: "up-regulation of SOD-2" RELATED [GOC:TermGenie] synonym: "up-regulation of SOD-3" RELATED [GOC:TermGenie] synonym: "up-regulation of SOD-4" RELATED [GOC:TermGenie] synonym: "up-regulation of SODF" RELATED [GOC:TermGenie] synonym: "up-regulation of SODS" RELATED [GOC:TermGenie] synonym: "up-regulation of superoxide dismutase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of superoxide dismutase I" RELATED [GOC:TermGenie] synonym: "up-regulation of superoxide dismutase II" RELATED [GOC:TermGenie] synonym: "up-regulation of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "upregulation of copper, zinc superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "upregulation of Cu,Zn-SOD" RELATED [GOC:TermGenie] synonym: "upregulation of Cu-Zn superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "upregulation of cuprein" RELATED [GOC:TermGenie] synonym: "upregulation of cytocuprein" RELATED [GOC:TermGenie] synonym: "upregulation of erythrocuprein" RELATED [GOC:TermGenie] synonym: "upregulation of Fe-SOD" RELATED [GOC:TermGenie] synonym: "upregulation of ferrisuperoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "upregulation of hemocuprein" RELATED [GOC:TermGenie] synonym: "upregulation of hepatocuprein" RELATED [GOC:TermGenie] synonym: "upregulation of iron superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "upregulation of iron superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "upregulation of manganese superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "upregulation of manganese superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "upregulation of Mn, Fe superoxide dismutase" NARROW [GOC:TermGenie] synonym: "upregulation of Mn-SOD" RELATED [GOC:TermGenie] synonym: "upregulation of nickel superoxide dismutase activity" NARROW [GOC:TermGenie] synonym: "upregulation of nickel superoxide oxidoreductase" RELATED [GOC:TermGenie] synonym: "upregulation of SOD" RELATED [GOC:TermGenie] synonym: "upregulation of SOD-1" RELATED [GOC:TermGenie] synonym: "upregulation of SOD-2" RELATED [GOC:TermGenie] synonym: "upregulation of SOD-3" RELATED [GOC:TermGenie] synonym: "upregulation of SOD-4" RELATED [GOC:TermGenie] synonym: "upregulation of SODF" RELATED [GOC:TermGenie] synonym: "upregulation of SODS" RELATED [GOC:TermGenie] synonym: "upregulation of superoxide dismutase activity" EXACT [GOC:TermGenie] synonym: "upregulation of superoxide dismutase I" RELATED [GOC:TermGenie] synonym: "upregulation of superoxide dismutase II" RELATED [GOC:TermGenie] synonym: "upregulation of superoxide:superoxide oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "upregulation of zinc superoxide oxidoreductase" RELATED [GOC:TermGenie] is_a: GO:0051353 ! positive regulation of oxidoreductase activity is_a: GO:1901668 ! regulation of superoxide dismutase activity created_by: tb creation_date: 2012-11-21T21:36:11Z [Term] id: GO:1901841 name: regulation of high voltage-gated calcium channel activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of high voltage-gated calcium channel activity." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12754254] subset: gocheck_obsoletion_candidate synonym: "regulation of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "regulation of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] is_a: GO:1901385 ! regulation of voltage-gated calcium channel activity created_by: rl creation_date: 2013-01-24T19:02:15Z [Term] id: GO:1901842 name: negative regulation of high voltage-gated calcium channel activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of high voltage-gated calcium channel activity." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12754254] subset: gocheck_obsoletion_candidate synonym: "down regulation of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "down regulation of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] synonym: "down regulation of high voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of high voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of high voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "inhibition of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "inhibition of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] synonym: "inhibition of high voltage-gated calcium channel activity" NARROW [GOC:TermGenie] synonym: "negative regulation of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "negative regulation of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] is_a: GO:1901386 ! negative regulation of voltage-gated calcium channel activity is_a: GO:1901841 ! regulation of high voltage-gated calcium channel activity created_by: rl creation_date: 2013-01-24T19:02:20Z [Term] id: GO:1901843 name: positive regulation of high voltage-gated calcium channel activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of high voltage-gated calcium channel activity." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12754254] subset: gocheck_obsoletion_candidate synonym: "activation of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "activation of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] synonym: "activation of high voltage-gated calcium channel activity" NARROW [GOC:TermGenie] synonym: "positive regulation of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "positive regulation of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of high voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of high voltage-gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of high voltage gated calcium channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of high voltage-dependent calcium channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of high voltage-gated calcium channel activity" EXACT [GOC:TermGenie] is_a: GO:1901387 ! positive regulation of voltage-gated calcium channel activity is_a: GO:1901841 ! regulation of high voltage-gated calcium channel activity created_by: rl creation_date: 2013-01-24T19:02:25Z [Term] id: GO:1901894 name: regulation of ATPase-coupled calcium transmembrane transporter activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19708671] subset: gocheck_obsoletion_candidate synonym: "regulation of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] synonym: "regulation of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of calcium ABC transporter" NARROW [GOC:TermGenie] synonym: "regulation of calcium efflux ATPase" NARROW [GOC:TermGenie] synonym: "regulation of calcium pump" BROAD [GOC:TermGenie] synonym: "regulation of calcium transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] synonym: "regulation of calcium-transporting ATPase activity" EXACT [] synonym: "regulation of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] synonym: "regulation of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] synonym: "regulation of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] is_a: GO:0043462 ! regulation of ATP-dependent activity is_a: GO:1901019 ! regulation of calcium ion transmembrane transporter activity created_by: rl creation_date: 2013-02-06T21:18:16Z [Term] id: GO:1901895 name: negative regulation of ATPase-coupled calcium transmembrane transporter activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19708671] subset: gocheck_obsoletion_candidate synonym: "down regulation of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] synonym: "down regulation of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "down regulation of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] synonym: "down regulation of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "down regulation of calcium ABC transporter" NARROW [GOC:TermGenie] synonym: "down regulation of calcium efflux ATPase" NARROW [GOC:TermGenie] synonym: "down regulation of calcium pump" BROAD [GOC:TermGenie] synonym: "down regulation of calcium transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "down regulation of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] synonym: "down regulation of calcium-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "down regulation of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] synonym: "down regulation of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] synonym: "down regulation of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] synonym: "down-regulation of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] synonym: "down-regulation of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of calcium ABC transporter" NARROW [GOC:TermGenie] synonym: "down-regulation of calcium efflux ATPase" NARROW [GOC:TermGenie] synonym: "down-regulation of calcium pump" BROAD [GOC:TermGenie] synonym: "down-regulation of calcium transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] synonym: "down-regulation of calcium-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] synonym: "down-regulation of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] synonym: "down-regulation of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] synonym: "downregulation of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] synonym: "downregulation of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "downregulation of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] synonym: "downregulation of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "downregulation of calcium ABC transporter" NARROW [GOC:TermGenie] synonym: "downregulation of calcium efflux ATPase" NARROW [GOC:TermGenie] synonym: "downregulation of calcium pump" BROAD [GOC:TermGenie] synonym: "downregulation of calcium transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "downregulation of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] synonym: "downregulation of calcium-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "downregulation of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] synonym: "downregulation of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] synonym: "downregulation of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] synonym: "inhibition of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] synonym: "inhibition of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "inhibition of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] synonym: "inhibition of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "inhibition of calcium ABC transporter" NARROW [GOC:TermGenie] synonym: "inhibition of calcium efflux ATPase" NARROW [GOC:TermGenie] synonym: "inhibition of calcium pump" BROAD [GOC:TermGenie] synonym: "inhibition of calcium transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "inhibition of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] synonym: "inhibition of calcium-transporting ATPase activity" NARROW [GOC:TermGenie] synonym: "inhibition of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] synonym: "inhibition of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] synonym: "inhibition of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] synonym: "negative regulation of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] synonym: "negative regulation of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of calcium ABC transporter" NARROW [GOC:TermGenie] synonym: "negative regulation of calcium efflux ATPase" NARROW [GOC:TermGenie] synonym: "negative regulation of calcium pump" BROAD [GOC:TermGenie] synonym: "negative regulation of calcium transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of calcium-transporting ATPase activity" EXACT [] synonym: "negative regulation of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] synonym: "negative regulation of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] synonym: "negative regulation of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] is_a: GO:0032780 ! negative regulation of ATP-dependent activity is_a: GO:1901020 ! negative regulation of calcium ion transmembrane transporter activity is_a: GO:1901894 ! regulation of ATPase-coupled calcium transmembrane transporter activity created_by: rl creation_date: 2013-02-06T21:18:25Z [Term] id: GO:1901896 name: positive regulation of ATPase-coupled calcium transmembrane transporter activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19708671] subset: gocheck_obsoletion_candidate synonym: "activation of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] synonym: "activation of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "activation of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] synonym: "activation of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "activation of calcium ABC transporter" NARROW [GOC:TermGenie] synonym: "activation of calcium efflux ATPase" NARROW [GOC:TermGenie] synonym: "activation of calcium pump" BROAD [GOC:TermGenie] synonym: "activation of calcium transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "activation of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] synonym: "activation of calcium-transporting ATPase activity" NARROW [GOC:TermGenie] synonym: "activation of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] synonym: "activation of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] synonym: "activation of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] synonym: "positive regulation of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] synonym: "positive regulation of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of calcium ABC transporter" NARROW [GOC:TermGenie] synonym: "positive regulation of calcium efflux ATPase" NARROW [GOC:TermGenie] synonym: "positive regulation of calcium pump" BROAD [GOC:TermGenie] synonym: "positive regulation of calcium transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of calcium-transporting ATPase activity" EXACT [] synonym: "positive regulation of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] synonym: "positive regulation of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] synonym: "positive regulation of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] synonym: "up regulation of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] synonym: "up regulation of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "up regulation of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] synonym: "up regulation of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "up regulation of calcium ABC transporter" NARROW [GOC:TermGenie] synonym: "up regulation of calcium efflux ATPase" NARROW [GOC:TermGenie] synonym: "up regulation of calcium pump" BROAD [GOC:TermGenie] synonym: "up regulation of calcium transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "up regulation of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] synonym: "up regulation of calcium-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "up regulation of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] synonym: "up regulation of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] synonym: "up regulation of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] synonym: "up-regulation of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] synonym: "up-regulation of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of calcium ABC transporter" NARROW [GOC:TermGenie] synonym: "up-regulation of calcium efflux ATPase" NARROW [GOC:TermGenie] synonym: "up-regulation of calcium pump" BROAD [GOC:TermGenie] synonym: "up-regulation of calcium transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of calcium-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] synonym: "up-regulation of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] synonym: "up-regulation of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] synonym: "upregulation of ATP phosphohydrolase (Ca2+-transporting)" EXACT [GOC:TermGenie] synonym: "upregulation of Ca(2+)-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "upregulation of Ca2+-pumping ATPase activity" EXACT [GOC:TermGenie] synonym: "upregulation of Ca2+-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "upregulation of calcium ABC transporter" NARROW [GOC:TermGenie] synonym: "upregulation of calcium efflux ATPase" NARROW [GOC:TermGenie] synonym: "upregulation of calcium pump" BROAD [GOC:TermGenie] synonym: "upregulation of calcium transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "upregulation of calcium-translocating P-type ATPase activity" NARROW [GOC:TermGenie] synonym: "upregulation of calcium-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "upregulation of plasma membrane Ca-ATPase" NARROW [GOC:TermGenie] synonym: "upregulation of sarco(endo)plasmic reticulum Ca2+-ATPase" NARROW [GOC:TermGenie] synonym: "upregulation of sarcoplasmic reticulum ATPase" NARROW [GOC:TermGenie] is_a: GO:0032781 ! positive regulation of ATP-dependent activity is_a: GO:1901021 ! positive regulation of calcium ion transmembrane transporter activity is_a: GO:1901894 ! regulation of ATPase-coupled calcium transmembrane transporter activity created_by: rl creation_date: 2013-02-06T21:18:29Z [Term] id: GO:1901919 name: positive regulation of exoribonuclease activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of exoribonuclease activity." [GOC:TermGenie, PMID:22570495] subset: gocheck_obsoletion_candidate synonym: "activation of exoribonuclease activity" NARROW [GOC:TermGenie] synonym: "up regulation of exoribonuclease activity" EXACT [GOC:TermGenie] synonym: "up-regulation of exoribonuclease activity" EXACT [GOC:TermGenie] synonym: "upregulation of exoribonuclease activity" EXACT [GOC:TermGenie] is_a: GO:0032075 ! positive regulation of nuclease activity is_a: GO:0060700 ! regulation of ribonuclease activity created_by: rb creation_date: 2013-02-15T00:58:07Z [Term] id: GO:1901979 name: regulation of inward rectifier potassium channel activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of inward rectifier potassium channel activity." [GOC:TermGenie, PMID:23449501] subset: gocheck_obsoletion_candidate synonym: "regulation of Kir channel activity" EXACT [GOC:TermGenie] is_a: GO:1901016 ! regulation of potassium ion transmembrane transporter activity is_a: GO:2001257 ! regulation of cation channel activity created_by: tb creation_date: 2013-03-12T18:21:12Z [Term] id: GO:1901980 name: positive regulation of inward rectifier potassium channel activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of inward rectifier potassium channel activity." [GOC:TermGenie, PMID:23449501] subset: gocheck_obsoletion_candidate synonym: "activation of inward rectifier potassium channel activity" NARROW [GOC:TermGenie] synonym: "activation of Kir channel activity" EXACT [GOC:TermGenie] synonym: "positive regulation of Kir channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of inward rectifier potassium channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of Kir channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of inward rectifier potassium channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of Kir channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of inward rectifier potassium channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of Kir channel activity" EXACT [GOC:TermGenie] is_a: GO:1901979 ! regulation of inward rectifier potassium channel activity is_a: GO:1903818 ! positive regulation of voltage-gated potassium channel activity created_by: tb creation_date: 2013-03-12T18:21:17Z [Term] id: GO:1901983 name: regulation of protein acetylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein acetylation." [GOC:TermGenie, PMID:22117195] subset: gocheck_obsoletion_candidate synonym: "regulation of protein amino acid acetylation" EXACT [GOC:TermGenie] relationship: regulates GO:0006473 ! protein acetylation created_by: ss creation_date: 2013-03-14T00:40:07Z [Term] id: GO:1901984 name: negative regulation of protein acetylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein acetylation." [GOC:TermGenie, PMID:22117195] subset: gocheck_obsoletion_candidate synonym: "down regulation of protein acetylation" EXACT [GOC:TermGenie] synonym: "down regulation of protein amino acid acetylation" EXACT [GOC:TermGenie] synonym: "down-regulation of protein acetylation" EXACT [GOC:TermGenie] synonym: "down-regulation of protein amino acid acetylation" EXACT [GOC:TermGenie] synonym: "downregulation of protein acetylation" EXACT [GOC:TermGenie] synonym: "downregulation of protein amino acid acetylation" EXACT [GOC:TermGenie] synonym: "inhibition of protein acetylation" NARROW [GOC:TermGenie] synonym: "inhibition of protein amino acid acetylation" NARROW [GOC:TermGenie] synonym: "negative regulation of protein amino acid acetylation" EXACT [GOC:TermGenie] is_a: GO:0031400 ! negative regulation of protein modification process is_a: GO:1901983 ! regulation of protein acetylation relationship: negatively_regulates GO:0006473 ! protein acetylation created_by: ss creation_date: 2013-03-14T00:40:11Z [Term] id: GO:1901985 name: positive regulation of protein acetylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein acetylation." [GOC:TermGenie, PMID:22117195] subset: gocheck_obsoletion_candidate synonym: "activation of protein acetylation" NARROW [GOC:TermGenie] synonym: "activation of protein amino acid acetylation" NARROW [GOC:TermGenie] synonym: "positive regulation of protein amino acid acetylation" EXACT [GOC:TermGenie] synonym: "up regulation of protein acetylation" EXACT [GOC:TermGenie] synonym: "up regulation of protein amino acid acetylation" EXACT [GOC:TermGenie] synonym: "up-regulation of protein acetylation" EXACT [GOC:TermGenie] synonym: "up-regulation of protein amino acid acetylation" EXACT [GOC:TermGenie] synonym: "upregulation of protein acetylation" EXACT [GOC:TermGenie] synonym: "upregulation of protein amino acid acetylation" EXACT [GOC:TermGenie] is_a: GO:0031401 ! positive regulation of protein modification process is_a: GO:1901983 ! regulation of protein acetylation relationship: positively_regulates GO:0006473 ! protein acetylation created_by: ss creation_date: 2013-03-14T00:40:19Z [Term] id: GO:1902083 name: negative regulation of peptidyl-cysteine S-nitrosylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-cysteine S-nitrosylation." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19198614] subset: gocheck_obsoletion_candidate synonym: "down regulation of peptidyl-cysteine S-nitrosylation" EXACT [GOC:TermGenie] synonym: "down regulation of protein S-nitrosylation" EXACT [GOC:TermGenie] synonym: "down regulation of S-nitrosylation" EXACT [GOC:TermGenie] synonym: "down-regulation of peptidyl-cysteine S-nitrosylation" EXACT [GOC:TermGenie] synonym: "down-regulation of protein S-nitrosylation" EXACT [GOC:TermGenie] synonym: "down-regulation of S-nitrosylation" EXACT [GOC:TermGenie] synonym: "downregulation of peptidyl-cysteine S-nitrosylation" EXACT [GOC:TermGenie] synonym: "downregulation of protein S-nitrosylation" EXACT [GOC:TermGenie] synonym: "downregulation of S-nitrosylation" EXACT [GOC:TermGenie] synonym: "inhibition of peptidyl-cysteine S-nitrosylation" NARROW [GOC:TermGenie] synonym: "inhibition of protein S-nitrosylation" EXACT [GOC:TermGenie] synonym: "inhibition of S-nitrosylation" EXACT [GOC:TermGenie] synonym: "negative regulation of protein S-nitrosylation" EXACT [GOC:TermGenie] synonym: "negative regulation of S-nitrosylation" EXACT [GOC:TermGenie] is_a: GO:0031400 ! negative regulation of protein modification process is_a: GO:2000169 ! regulation of peptidyl-cysteine S-nitrosylation relationship: negatively_regulates GO:0018119 ! peptidyl-cysteine S-nitrosylation created_by: rl creation_date: 2013-04-24T16:49:34Z [Term] id: GO:1902159 name: regulation of cyclic nucleotide-gated ion channel activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cyclic nucleotide-gated ion channel activity." [GOC:TermGenie, PMID:11420311] subset: gocheck_obsoletion_candidate synonym: "regulation of cyclic nucleotide activated ion channel activity" EXACT [GOC:TermGenie] synonym: "regulation of cyclic nucleotide gated ion channel activity" EXACT [GOC:TermGenie] synonym: "regulation of cyclic nucleotide-activated ion channel activity" EXACT [GOC:TermGenie] is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity created_by: sl creation_date: 2013-05-21T19:24:30Z [Term] id: GO:1902161 name: positive regulation of cyclic nucleotide-gated ion channel activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cyclic nucleotide-gated ion channel activity." [GOC:TermGenie, PMID:11420311] subset: gocheck_obsoletion_candidate synonym: "activation of cyclic nucleotide activated ion channel activity" EXACT [GOC:TermGenie] synonym: "activation of cyclic nucleotide gated ion channel activity" EXACT [GOC:TermGenie] synonym: "activation of cyclic nucleotide-activated ion channel activity" EXACT [GOC:TermGenie] synonym: "activation of cyclic nucleotide-gated ion channel activity" NARROW [GOC:TermGenie] synonym: "positive regulation of cyclic nucleotide activated ion channel activity" EXACT [GOC:TermGenie] synonym: "positive regulation of cyclic nucleotide gated ion channel activity" EXACT [GOC:TermGenie] synonym: "positive regulation of cyclic nucleotide-activated ion channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of cyclic nucleotide activated ion channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of cyclic nucleotide gated ion channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of cyclic nucleotide-activated ion channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of cyclic nucleotide-gated ion channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of cyclic nucleotide activated ion channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of cyclic nucleotide gated ion channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of cyclic nucleotide-activated ion channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of cyclic nucleotide-gated ion channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of cyclic nucleotide activated ion channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of cyclic nucleotide gated ion channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of cyclic nucleotide-activated ion channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of cyclic nucleotide-gated ion channel activity" EXACT [GOC:TermGenie] is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity is_a: GO:1902159 ! regulation of cyclic nucleotide-gated ion channel activity created_by: sl creation_date: 2013-05-21T19:24:48Z [Term] id: GO:1902171 name: regulation of tocopherol cyclase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of tocopherol cyclase activity." [GOC:TermGenie, PMID:23632854] subset: gocheck_obsoletion_candidate is_a: GO:0050790 ! regulation of catalytic activity created_by: tb creation_date: 2013-05-25T00:41:14Z [Term] id: GO:1902259 name: regulation of delayed rectifier potassium channel activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of delayed rectifier potassium channel activity." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11299204] subset: gocheck_obsoletion_candidate is_a: GO:1901016 ! regulation of potassium ion transmembrane transporter activity is_a: GO:2001257 ! regulation of cation channel activity created_by: rl creation_date: 2013-06-25T12:16:19Z [Term] id: GO:1902260 name: negative regulation of delayed rectifier potassium channel activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of delayed rectifier potassium channel activity." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:11299204] subset: gocheck_obsoletion_candidate synonym: "down regulation of delayed rectifier potassium channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of delayed rectifier potassium channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of delayed rectifier potassium channel activity" EXACT [GOC:TermGenie] synonym: "inhibition of delayed rectifier potassium channel activity" NARROW [GOC:TermGenie] is_a: GO:1902259 ! regulation of delayed rectifier potassium channel activity is_a: GO:1903817 ! negative regulation of voltage-gated potassium channel activity created_by: rl creation_date: 2013-06-25T12:16:24Z [Term] id: GO:1902261 name: positive regulation of delayed rectifier potassium channel activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of delayed rectifier potassium channel activity." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11299204] subset: gocheck_obsoletion_candidate synonym: "activation of delayed rectifier potassium channel activity" NARROW [GOC:TermGenie] synonym: "up regulation of delayed rectifier potassium channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of delayed rectifier potassium channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of delayed rectifier potassium channel activity" EXACT [GOC:TermGenie] is_a: GO:1902259 ! regulation of delayed rectifier potassium channel activity is_a: GO:1903818 ! positive regulation of voltage-gated potassium channel activity created_by: rl creation_date: 2013-06-25T12:16:30Z [Term] id: GO:1902280 name: regulation of RNA helicase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of ATP-dependent RNA helicase activity." [GOC:rb, GOC:TermGenie, PMID:23721653] subset: gocheck_obsoletion_candidate synonym: "regulation of ATP-dependent RNA helicase activity" EXACT [] is_a: GO:0043462 ! regulation of ATP-dependent activity is_a: GO:0050790 ! regulation of catalytic activity created_by: rb creation_date: 2013-07-03T18:05:19Z [Term] id: GO:1902283 name: negative regulation of primary amine oxidase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of primary amine oxidase activity." [GOC:TermGenie, PMID:23349812] subset: gocheck_obsoletion_candidate synonym: "down regulation of amine oxidase (copper-containing) activity" NARROW [GOC:TermGenie] synonym: "down regulation of primary amine oxidase activity" EXACT [GOC:TermGenie] synonym: "down regulation of primary-amine:oxygen oxidoreductase (deaminating) activity" EXACT [GOC:TermGenie] synonym: "down-regulation of amine oxidase (copper-containing) activity" NARROW [GOC:TermGenie] synonym: "down-regulation of primary amine oxidase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of primary-amine:oxygen oxidoreductase (deaminating) activity" EXACT [GOC:TermGenie] synonym: "downregulation of amine oxidase (copper-containing) activity" NARROW [GOC:TermGenie] synonym: "downregulation of primary amine oxidase activity" EXACT [GOC:TermGenie] synonym: "downregulation of primary-amine:oxygen oxidoreductase (deaminating) activity" EXACT [GOC:TermGenie] synonym: "inhibition of amine oxidase (copper-containing) activity" NARROW [GOC:TermGenie] synonym: "inhibition of primary amine oxidase activity" NARROW [GOC:TermGenie] synonym: "inhibition of primary-amine:oxygen oxidoreductase (deaminating) activity" NARROW [GOC:TermGenie] synonym: "negative regulation of amine oxidase (copper-containing) activity" NARROW [GOC:TermGenie] synonym: "negative regulation of primary-amine:oxygen oxidoreductase (deaminating) activity" EXACT [GOC:TermGenie] is_a: GO:0051354 ! negative regulation of oxidoreductase activity created_by: ecu creation_date: 2013-07-08T13:27:59Z [Term] id: GO:1902380 name: positive regulation of endoribonuclease activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endoribonuclease activity." [GOC:bf, GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "activation of endonuclease G activity" RELATED [GOC:TermGenie] synonym: "activation of endoribonuclease activity" NARROW [GOC:TermGenie] synonym: "positive regulation of endonuclease G activity" RELATED [GOC:TermGenie] synonym: "up regulation of endonuclease G activity" RELATED [GOC:TermGenie] synonym: "up regulation of endoribonuclease activity" EXACT [GOC:TermGenie] synonym: "up-regulation of endonuclease G activity" RELATED [GOC:TermGenie] synonym: "up-regulation of endoribonuclease activity" EXACT [GOC:TermGenie] synonym: "upregulation of endonuclease G activity" RELATED [GOC:TermGenie] synonym: "upregulation of endoribonuclease activity" EXACT [GOC:TermGenie] is_a: GO:0032075 ! positive regulation of nuclease activity is_a: GO:0060699 ! regulation of endoribonuclease activity created_by: bf creation_date: 2013-09-02T14:14:29Z [Term] id: GO:1902427 name: regulation of water channel activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of water channel activity." [GOC:nhn, GOC:TermGenie, PMID:22095752] subset: gocheck_obsoletion_candidate synonym: "regulation of aquaporin" NARROW [GOC:TermGenie] synonym: "regulation of aquaporin permeability" NARROW [PMID:22095752] is_a: GO:0022898 ! regulation of transmembrane transporter activity created_by: bf creation_date: 2013-09-23T12:56:31Z [Term] id: GO:1902551 name: regulation of catalase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of catalase activity." [GOC:TermGenie, PMID:24285797] subset: gocheck_obsoletion_candidate synonym: "regulation of bacterial catalase-peroxidase activity" NARROW [GOC:TermGenie] synonym: "regulation of caperase activity" EXACT [GOC:TermGenie] synonym: "regulation of CAT" RELATED [GOC:TermGenie] synonym: "regulation of catalase reaction" EXACT [GOC:TermGenie] synonym: "regulation of catalase-peroxidase activity" EXACT [GOC:TermGenie] synonym: "regulation of equilase activity" EXACT [GOC:TermGenie] synonym: "regulation of haem catalase activity" NARROW [GOC:TermGenie] synonym: "regulation of heme catalase activity" NARROW [GOC:TermGenie] synonym: "regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "regulation of manganese catalase activity" NARROW [GOC:TermGenie] synonym: "regulation of optidase activity" EXACT [GOC:TermGenie] is_a: GO:0051341 ! regulation of oxidoreductase activity created_by: tb creation_date: 2013-12-04T21:55:46Z [Term] id: GO:1902553 name: positive regulation of catalase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of catalase activity." [GOC:TermGenie, PMID:24285797] subset: gocheck_obsoletion_candidate synonym: "activation of bacterial catalase-peroxidase activity" NARROW [GOC:TermGenie] synonym: "activation of caperase activity" NARROW [GOC:TermGenie] synonym: "activation of CAT" RELATED [GOC:TermGenie] synonym: "activation of catalase activity" NARROW [GOC:TermGenie] synonym: "activation of catalase reaction" NARROW [GOC:TermGenie] synonym: "activation of catalase-peroxidase activity" NARROW [GOC:TermGenie] synonym: "activation of equilase activity" NARROW [GOC:TermGenie] synonym: "activation of haem catalase activity" NARROW [GOC:TermGenie] synonym: "activation of heme catalase activity" NARROW [GOC:TermGenie] synonym: "activation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity" NARROW [GOC:TermGenie] synonym: "activation of manganese catalase activity" NARROW [GOC:TermGenie] synonym: "activation of optidase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of bacterial catalase-peroxidase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of caperase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of CAT" RELATED [GOC:TermGenie] synonym: "positive regulation of catalase reaction" EXACT [GOC:TermGenie] synonym: "positive regulation of catalase-peroxidase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of equilase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of haem catalase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of heme catalase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of manganese catalase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of optidase activity" EXACT [GOC:TermGenie] synonym: "up regulation of bacterial catalase-peroxidase activity" NARROW [GOC:TermGenie] synonym: "up regulation of caperase activity" EXACT [GOC:TermGenie] synonym: "up regulation of CAT" RELATED [GOC:TermGenie] synonym: "up regulation of catalase activity" EXACT [GOC:TermGenie] synonym: "up regulation of catalase reaction" EXACT [GOC:TermGenie] synonym: "up regulation of catalase-peroxidase activity" EXACT [GOC:TermGenie] synonym: "up regulation of equilase activity" EXACT [GOC:TermGenie] synonym: "up regulation of haem catalase activity" NARROW [GOC:TermGenie] synonym: "up regulation of heme catalase activity" NARROW [GOC:TermGenie] synonym: "up regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "up regulation of manganese catalase activity" NARROW [GOC:TermGenie] synonym: "up regulation of optidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of bacterial catalase-peroxidase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of caperase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of CAT" RELATED [GOC:TermGenie] synonym: "up-regulation of catalase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of catalase reaction" EXACT [GOC:TermGenie] synonym: "up-regulation of catalase-peroxidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of equilase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of haem catalase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of heme catalase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of manganese catalase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of optidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of bacterial catalase-peroxidase activity" NARROW [GOC:TermGenie] synonym: "upregulation of caperase activity" EXACT [GOC:TermGenie] synonym: "upregulation of CAT" RELATED [GOC:TermGenie] synonym: "upregulation of catalase activity" EXACT [GOC:TermGenie] synonym: "upregulation of catalase reaction" EXACT [GOC:TermGenie] synonym: "upregulation of catalase-peroxidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of equilase activity" EXACT [GOC:TermGenie] synonym: "upregulation of haem catalase activity" NARROW [GOC:TermGenie] synonym: "upregulation of heme catalase activity" NARROW [GOC:TermGenie] synonym: "upregulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "upregulation of manganese catalase activity" NARROW [GOC:TermGenie] synonym: "upregulation of optidase activity" EXACT [GOC:TermGenie] is_a: GO:1902551 ! regulation of catalase activity is_a: GO:2000470 ! positive regulation of peroxidase activity created_by: tb creation_date: 2013-12-04T21:56:03Z [Term] id: GO:1902572 name: negative regulation of serine-type peptidase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of serine-type peptidase activity." [GOC:krc, GOC:TermGenie, PMID:20179351] subset: gocheck_obsoletion_candidate synonym: "down regulation of serine protease activity" NARROW [GOC:TermGenie] synonym: "down regulation of serine-type peptidase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of serine protease activity" NARROW [GOC:TermGenie] synonym: "down-regulation of serine-type peptidase activity" EXACT [GOC:TermGenie] synonym: "downregulation of serine protease activity" NARROW [GOC:TermGenie] synonym: "downregulation of serine-type peptidase activity" EXACT [GOC:TermGenie] synonym: "inhibition of serine protease activity" NARROW [GOC:TermGenie] synonym: "inhibition of serine-type peptidase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of serine protease activity" NARROW [GOC:TermGenie] is_a: GO:0010466 ! negative regulation of peptidase activity created_by: krc creation_date: 2013-12-10T18:17:07Z [Term] id: GO:1902607 name: negative regulation of large conductance calcium-activated potassium channel activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of large conductance calcium-activated potassium channel activity." [GO_REF:0000059, GOC:TermGenie, PMID:23407708] subset: gocheck_obsoletion_candidate synonym: "down regulation of BK calcium-activated potassium channel activity" EXACT [GOC:TermGenie] synonym: "down regulation of BK channel activity" RELATED [GOC:TermGenie] synonym: "down regulation of BK KCa channels" EXACT [GOC:TermGenie] synonym: "down regulation of large conductance calcium-activated potassium channel activity" EXACT [GOC:TermGenie] synonym: "down regulation of large conductance KCa channels" EXACT [GOC:TermGenie] synonym: "down-regulation of BK calcium-activated potassium channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of BK channel activity" RELATED [GOC:TermGenie] synonym: "down-regulation of BK KCa channels" EXACT [GOC:TermGenie] synonym: "down-regulation of large conductance calcium-activated potassium channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of large conductance KCa channels" EXACT [GOC:TermGenie] synonym: "downregulation of BK calcium-activated potassium channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of BK channel activity" RELATED [GOC:TermGenie] synonym: "downregulation of BK KCa channels" EXACT [GOC:TermGenie] synonym: "downregulation of large conductance calcium-activated potassium channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of large conductance KCa channels" EXACT [GOC:TermGenie] synonym: "inhibition of BK calcium-activated potassium channel activity" NARROW [GOC:TermGenie] synonym: "inhibition of BK channel activity" RELATED [GOC:TermGenie] synonym: "inhibition of BK KCa channels" NARROW [GOC:TermGenie] synonym: "inhibition of large conductance calcium-activated potassium channel activity" NARROW [GOC:TermGenie] synonym: "inhibition of large conductance KCa channels" NARROW [GOC:TermGenie] synonym: "negative regulation of BK calcium-activated potassium channel activity" EXACT [GOC:TermGenie] synonym: "negative regulation of BK channel activity" RELATED [GOC:TermGenie] synonym: "negative regulation of BK KCa channels" EXACT [GOC:TermGenie] synonym: "negative regulation of large conductance KCa channels" EXACT [GOC:TermGenie] is_a: GO:1901017 ! negative regulation of potassium ion transmembrane transporter activity is_a: GO:2001258 ! negative regulation of cation channel activity created_by: sl creation_date: 2014-01-02T18:51:12Z [Term] id: GO:1902608 name: positive regulation of large conductance calcium-activated potassium channel activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of large conductance calcium-activated potassium channel activity." [GO_REF:0000059, GOC:TermGenie, PMID:23407708] subset: gocheck_obsoletion_candidate synonym: "activation of BK calcium-activated potassium channel activity" NARROW [GOC:TermGenie] synonym: "activation of BK channel activity" RELATED [GOC:TermGenie] synonym: "activation of BK KCa channels" NARROW [GOC:TermGenie] synonym: "activation of large conductance calcium-activated potassium channel activity" NARROW [GOC:TermGenie] synonym: "activation of large conductance KCa channels" NARROW [GOC:TermGenie] synonym: "positive regulation of BK calcium-activated potassium channel activity" EXACT [GOC:TermGenie] synonym: "positive regulation of BK channel activity" RELATED [GOC:TermGenie] synonym: "positive regulation of BK KCa channels" EXACT [GOC:TermGenie] synonym: "positive regulation of large conductance KCa channels" EXACT [GOC:TermGenie] synonym: "up regulation of BK calcium-activated potassium channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of BK channel activity" RELATED [GOC:TermGenie] synonym: "up regulation of BK KCa channels" EXACT [GOC:TermGenie] synonym: "up regulation of large conductance calcium-activated potassium channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of large conductance KCa channels" EXACT [GOC:TermGenie] synonym: "up-regulation of BK calcium-activated potassium channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of BK channel activity" RELATED [GOC:TermGenie] synonym: "up-regulation of BK KCa channels" EXACT [GOC:TermGenie] synonym: "up-regulation of large conductance calcium-activated potassium channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of large conductance KCa channels" EXACT [GOC:TermGenie] synonym: "upregulation of BK calcium-activated potassium channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of BK channel activity" RELATED [GOC:TermGenie] synonym: "upregulation of BK KCa channels" EXACT [GOC:TermGenie] synonym: "upregulation of large conductance calcium-activated potassium channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of large conductance KCa channels" EXACT [GOC:TermGenie] is_a: GO:1901018 ! positive regulation of potassium ion transmembrane transporter activity is_a: GO:2001259 ! positive regulation of cation channel activity created_by: sl creation_date: 2014-01-02T18:51:21Z [Term] id: GO:1902662 name: regulation of peptidyl-L-cysteine S-palmitoylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation." [GO_REF:0000058, GOC:TermGenie, PMID:23444136] subset: gocheck_obsoletion_candidate synonym: "regulation of peptidyl-cysteine S-palmitoylation" EXACT [GOC:TermGenie] synonym: "regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [GOC:TermGenie] is_a: GO:1903059 ! regulation of protein lipidation relationship: regulates GO:0018230 ! peptidyl-L-cysteine S-palmitoylation created_by: mm2 creation_date: 2014-01-29T11:33:09Z [Term] id: GO:1902663 name: negative regulation of peptidyl-L-cysteine S-palmitoylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation." [GO_REF:0000058, GOC:TermGenie, PMID:23444136] subset: gocheck_obsoletion_candidate synonym: "down regulation of peptidyl-cysteine S-palmitoylation" EXACT [GOC:TermGenie] synonym: "down regulation of peptidyl-L-cysteine S-palmitoylation" EXACT [GOC:TermGenie] synonym: "down regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "down regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "down regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "down regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "down-regulation of peptidyl-cysteine S-palmitoylation" EXACT [GOC:TermGenie] synonym: "down-regulation of peptidyl-L-cysteine S-palmitoylation" EXACT [GOC:TermGenie] synonym: "down-regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "down-regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "down-regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "down-regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "downregulation of peptidyl-cysteine S-palmitoylation" EXACT [GOC:TermGenie] synonym: "downregulation of peptidyl-L-cysteine S-palmitoylation" EXACT [GOC:TermGenie] synonym: "downregulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "downregulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "downregulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "downregulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "inhibition of peptidyl-cysteine S-palmitoylation" NARROW [GOC:TermGenie] synonym: "inhibition of peptidyl-L-cysteine S-palmitoylation" NARROW [GOC:TermGenie] synonym: "inhibition of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" NARROW [GOC:TermGenie] synonym: "inhibition of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" NARROW [GOC:TermGenie] synonym: "inhibition of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" NARROW [GOC:TermGenie] synonym: "inhibition of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" NARROW [GOC:TermGenie] synonym: "negative regulation of peptidyl-cysteine S-palmitoylation" EXACT [GOC:TermGenie] synonym: "negative regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "negative regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "negative regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "negative regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [GOC:TermGenie] is_a: GO:1902662 ! regulation of peptidyl-L-cysteine S-palmitoylation is_a: GO:1903060 ! negative regulation of protein lipidation relationship: negatively_regulates GO:0018230 ! peptidyl-L-cysteine S-palmitoylation created_by: mm2 creation_date: 2014-01-29T11:33:19Z [Term] id: GO:1902664 name: positive regulation of peptidyl-L-cysteine S-palmitoylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation." [GO_REF:0000058, GOC:TermGenie, PMID:23444136] subset: gocheck_obsoletion_candidate synonym: "activation of peptidyl-cysteine S-palmitoylation" NARROW [GOC:TermGenie] synonym: "activation of peptidyl-L-cysteine S-palmitoylation" NARROW [GOC:TermGenie] synonym: "activation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" NARROW [GOC:TermGenie] synonym: "activation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" NARROW [GOC:TermGenie] synonym: "activation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" NARROW [GOC:TermGenie] synonym: "activation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" NARROW [GOC:TermGenie] synonym: "positive regulation of peptidyl-cysteine S-palmitoylation" EXACT [GOC:TermGenie] synonym: "positive regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "positive regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "positive regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "positive regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "up regulation of peptidyl-cysteine S-palmitoylation" EXACT [GOC:TermGenie] synonym: "up regulation of peptidyl-L-cysteine S-palmitoylation" EXACT [GOC:TermGenie] synonym: "up regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "up regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "up regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "up regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "up-regulation of peptidyl-cysteine S-palmitoylation" EXACT [GOC:TermGenie] synonym: "up-regulation of peptidyl-L-cysteine S-palmitoylation" EXACT [GOC:TermGenie] synonym: "up-regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "up-regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "up-regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "up-regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "upregulation of peptidyl-cysteine S-palmitoylation" EXACT [GOC:TermGenie] synonym: "upregulation of peptidyl-L-cysteine S-palmitoylation" EXACT [GOC:TermGenie] synonym: "upregulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "upregulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "upregulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine" EXACT [GOC:TermGenie] synonym: "upregulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine" EXACT [GOC:TermGenie] is_a: GO:1902662 ! regulation of peptidyl-L-cysteine S-palmitoylation is_a: GO:1903061 ! positive regulation of protein lipidation relationship: positively_regulates GO:0018230 ! peptidyl-L-cysteine S-palmitoylation created_by: mm2 creation_date: 2014-01-29T11:33:28Z [Term] id: GO:1902800 name: positive regulation of phosphodiesterase I activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of phosphodiesterase I activity." [GO_REF:0000059, GOC:TermGenie, PMID:24559510] subset: gocheck_obsoletion_candidate synonym: "activation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity" NARROW [GOC:TermGenie] synonym: "activation of 5'-exonuclease activity" RELATED [GOC:TermGenie] synonym: "activation of 5'-NPDase activity" RELATED [GOC:TermGenie] synonym: "activation of 5'-nucleotide phosphodiesterase activity" RELATED [GOC:TermGenie] synonym: "activation of 5'-PDase activity" RELATED [GOC:TermGenie] synonym: "activation of 5'-PDE activity" RELATED [GOC:TermGenie] synonym: "activation of 5'-phosphodiesterase activity" RELATED [GOC:TermGenie] synonym: "activation of 5'NPDE activity" RELATED [GOC:TermGenie] synonym: "activation of alkaline phosphodiesterase activity" RELATED [GOC:TermGenie] synonym: "activation of exonuclease I activity" RELATED [GOC:TermGenie] synonym: "activation of nucleotide pyrophosphatase/phosphodiesterase I activity" NARROW [GOC:TermGenie] synonym: "activation of oligonucleate 5'-nucleotidohydrolase activity" NARROW [GOC:TermGenie] synonym: "activation of orthophosphoric diester phosphohydrolase activity" NARROW [GOC:TermGenie] synonym: "activation of PDE I activity" NARROW [GOC:TermGenie] synonym: "activation of phosphodiesterase I activity" NARROW [GOC:TermGenie] synonym: "positive regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity" EXACT [GOC:TermGenie] synonym: "positive regulation of 5'-exonuclease activity" RELATED [GOC:TermGenie] synonym: "positive regulation of 5'-NPDase activity" RELATED [GOC:TermGenie] synonym: "positive regulation of 5'-nucleotide phosphodiesterase activity" RELATED [GOC:TermGenie] synonym: "positive regulation of 5'-PDase activity" RELATED [GOC:TermGenie] synonym: "positive regulation of 5'-PDE activity" RELATED [GOC:TermGenie] synonym: "positive regulation of 5'-phosphodiesterase activity" RELATED [GOC:TermGenie] synonym: "positive regulation of 5'NPDE activity" RELATED [GOC:TermGenie] synonym: "positive regulation of alkaline phosphodiesterase activity" RELATED [GOC:TermGenie] synonym: "positive regulation of exonuclease I activity" RELATED [GOC:TermGenie] synonym: "positive regulation of nucleotide pyrophosphatase/phosphodiesterase I activity" EXACT [GOC:TermGenie] synonym: "positive regulation of oligonucleate 5'-nucleotidohydrolase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of orthophosphoric diester phosphohydrolase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of PDE I activity" EXACT [GOC:TermGenie] synonym: "up regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity" EXACT [GOC:TermGenie] synonym: "up regulation of 5'-exonuclease activity" RELATED [GOC:TermGenie] synonym: "up regulation of 5'-NPDase activity" RELATED [GOC:TermGenie] synonym: "up regulation of 5'-nucleotide phosphodiesterase activity" RELATED [GOC:TermGenie] synonym: "up regulation of 5'-PDase activity" RELATED [GOC:TermGenie] synonym: "up regulation of 5'-PDE activity" RELATED [GOC:TermGenie] synonym: "up regulation of 5'-phosphodiesterase activity" RELATED [GOC:TermGenie] synonym: "up regulation of 5'NPDE activity" RELATED [GOC:TermGenie] synonym: "up regulation of alkaline phosphodiesterase activity" RELATED [GOC:TermGenie] synonym: "up regulation of exonuclease I activity" RELATED [GOC:TermGenie] synonym: "up regulation of nucleotide pyrophosphatase/phosphodiesterase I activity" EXACT [GOC:TermGenie] synonym: "up regulation of oligonucleate 5'-nucleotidohydrolase activity" EXACT [GOC:TermGenie] synonym: "up regulation of orthophosphoric diester phosphohydrolase activity" EXACT [GOC:TermGenie] synonym: "up regulation of PDE I activity" EXACT [GOC:TermGenie] synonym: "up regulation of phosphodiesterase I activity" EXACT [GOC:TermGenie] synonym: "up-regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity" EXACT [GOC:TermGenie] synonym: "up-regulation of 5'-exonuclease activity" RELATED [GOC:TermGenie] synonym: "up-regulation of 5'-NPDase activity" RELATED [GOC:TermGenie] synonym: "up-regulation of 5'-nucleotide phosphodiesterase activity" RELATED [GOC:TermGenie] synonym: "up-regulation of 5'-PDase activity" RELATED [GOC:TermGenie] synonym: "up-regulation of 5'-PDE activity" RELATED [GOC:TermGenie] synonym: "up-regulation of 5'-phosphodiesterase activity" RELATED [GOC:TermGenie] synonym: "up-regulation of 5'NPDE activity" RELATED [GOC:TermGenie] synonym: "up-regulation of alkaline phosphodiesterase activity" RELATED [GOC:TermGenie] synonym: "up-regulation of exonuclease I activity" RELATED [GOC:TermGenie] synonym: "up-regulation of nucleotide pyrophosphatase/phosphodiesterase I activity" EXACT [GOC:TermGenie] synonym: "up-regulation of oligonucleate 5'-nucleotidohydrolase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of orthophosphoric diester phosphohydrolase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of PDE I activity" EXACT [GOC:TermGenie] synonym: "up-regulation of phosphodiesterase I activity" EXACT [GOC:TermGenie] synonym: "upregulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity" EXACT [GOC:TermGenie] synonym: "upregulation of 5'-exonuclease activity" RELATED [GOC:TermGenie] synonym: "upregulation of 5'-NPDase activity" RELATED [GOC:TermGenie] synonym: "upregulation of 5'-nucleotide phosphodiesterase activity" RELATED [GOC:TermGenie] synonym: "upregulation of 5'-PDase activity" RELATED [GOC:TermGenie] synonym: "upregulation of 5'-PDE activity" RELATED [GOC:TermGenie] synonym: "upregulation of 5'-phosphodiesterase activity" RELATED [GOC:TermGenie] synonym: "upregulation of 5'NPDE activity" RELATED [GOC:TermGenie] synonym: "upregulation of alkaline phosphodiesterase activity" RELATED [GOC:TermGenie] synonym: "upregulation of exonuclease I activity" RELATED [GOC:TermGenie] synonym: "upregulation of nucleotide pyrophosphatase/phosphodiesterase I activity" EXACT [GOC:TermGenie] synonym: "upregulation of oligonucleate 5'-nucleotidohydrolase activity" EXACT [GOC:TermGenie] synonym: "upregulation of orthophosphoric diester phosphohydrolase activity" EXACT [GOC:TermGenie] synonym: "upregulation of PDE I activity" EXACT [GOC:TermGenie] synonym: "upregulation of phosphodiesterase I activity" EXACT [GOC:TermGenie] is_a: GO:0032075 ! positive regulation of nuclease activity created_by: al creation_date: 2014-03-25T08:55:54Z [Term] id: GO:1902943 name: positive regulation of voltage-gated chloride channel activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of voltage-gated chloride channel activity." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:22006324] subset: gocheck_obsoletion_candidate synonym: "activation of voltage gated chloride channel activity" NARROW [GOC:TermGenie] synonym: "activation of voltage-dependent chloride channel activity" NARROW [GOC:TermGenie] synonym: "activation of voltage-gated chloride channel activity" NARROW [GOC:TermGenie] synonym: "positive regulation of voltage gated chloride channel activity" EXACT [GOC:TermGenie] synonym: "positive regulation of voltage-dependent chloride channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of voltage gated chloride channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of voltage-dependent chloride channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of voltage-gated chloride channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of voltage gated chloride channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of voltage-dependent chloride channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of voltage-gated chloride channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of voltage gated chloride channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of voltage-dependent chloride channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of voltage-gated chloride channel activity" EXACT [GOC:TermGenie] is_a: GO:1901529 ! positive regulation of anion channel activity created_by: als creation_date: 2014-04-28T08:55:43Z [Term] id: GO:1902947 name: regulation of tau-protein kinase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of tau-protein kinase activity." [GO_REF:0000059, GOC:sjp, GOC:TermGenie, PMID:15897157, PMID:22986780] subset: gocheck_obsoletion_candidate synonym: "regulation of [Tau protein] kinase activity" EXACT [GOC:TermGenie] synonym: "regulation of ATP:tau-protein O-phosphotransferase activity" BROAD [GOC:TermGenie] synonym: "regulation of brain protein kinase PK40erk activity" NARROW [GOC:TermGenie] synonym: "regulation of cdk5/p20" RELATED [GOC:TermGenie] synonym: "regulation of CDK5/p23" RELATED [GOC:TermGenie] synonym: "regulation of glycogen synthase kinase-3beta activity" EXACT [GOC:TermGenie] synonym: "regulation of GSK" RELATED [GOC:TermGenie] synonym: "regulation of protein tau kinase activity" EXACT [GOC:TermGenie] synonym: "regulation of STK31" RELATED [GOC:TermGenie] synonym: "regulation of tau kinase activity" EXACT [GOC:TermGenie] synonym: "regulation of tau protein kinase activity" EXACT [GOC:TermGenie] synonym: "regulation of tau-protein kinase I activity" NARROW [GOC:TermGenie] synonym: "regulation of tau-protein kinase II activity" NARROW [GOC:TermGenie] synonym: "regulation of tau-tubulin kinase activity" NARROW [GOC:TermGenie] synonym: "regulation of TPK" RELATED [GOC:TermGenie] synonym: "regulation of TPK I" RELATED [GOC:TermGenie] synonym: "regulation of TPK II" RELATED [GOC:TermGenie] synonym: "regulation of TTK" RELATED [GOC:TermGenie] is_a: GO:0071900 ! regulation of protein serine/threonine kinase activity created_by: sjp creation_date: 2014-05-02T08:43:27Z [Term] id: GO:1902948 name: negative regulation of tau-protein kinase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of tau-protein kinase activity." [GO_REF:0000059, GOC:sjp, GOC:TermGenie, PMID:15897157, PMID:22986780] subset: gocheck_obsoletion_candidate synonym: "down regulation of [Tau protein] kinase activity" EXACT [GOC:TermGenie] synonym: "down regulation of brain protein kinase PK40erk activity" NARROW [GOC:TermGenie] synonym: "down regulation of cdk5/p20" RELATED [GOC:TermGenie] synonym: "down regulation of CDK5/p23" RELATED [GOC:TermGenie] synonym: "down regulation of glycogen synthase kinase-3beta activity" EXACT [GOC:TermGenie] synonym: "down regulation of GSK" RELATED [GOC:TermGenie] synonym: "down regulation of protein tau kinase activity" EXACT [GOC:TermGenie] synonym: "down regulation of STK31" RELATED [GOC:TermGenie] synonym: "down regulation of tau kinase activity" EXACT [GOC:TermGenie] synonym: "down regulation of tau protein kinase activity" EXACT [GOC:TermGenie] synonym: "down regulation of tau-protein kinase activity" EXACT [GOC:TermGenie] synonym: "down regulation of tau-protein kinase I activity" NARROW [GOC:TermGenie] synonym: "down regulation of tau-protein kinase II activity" NARROW [GOC:TermGenie] synonym: "down regulation of tau-tubulin kinase activity" NARROW [GOC:TermGenie] synonym: "down regulation of TPK" RELATED [GOC:TermGenie] synonym: "down regulation of TPK I" RELATED [GOC:TermGenie] synonym: "down regulation of TPK II" RELATED [GOC:TermGenie] synonym: "down regulation of TTK" RELATED [GOC:TermGenie] synonym: "down-regulation of [Tau protein] kinase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of brain protein kinase PK40erk activity" NARROW [GOC:TermGenie] synonym: "down-regulation of cdk5/p20" RELATED [GOC:TermGenie] synonym: "down-regulation of CDK5/p23" RELATED [GOC:TermGenie] synonym: "down-regulation of glycogen synthase kinase-3beta activity" EXACT [GOC:TermGenie] synonym: "down-regulation of GSK" RELATED [GOC:TermGenie] synonym: "down-regulation of protein tau kinase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of STK31" RELATED [GOC:TermGenie] synonym: "down-regulation of tau kinase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of tau protein kinase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of tau-protein kinase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of tau-protein kinase I activity" NARROW [GOC:TermGenie] synonym: "down-regulation of tau-protein kinase II activity" NARROW [GOC:TermGenie] synonym: "down-regulation of tau-tubulin kinase activity" NARROW [GOC:TermGenie] synonym: "down-regulation of TPK" RELATED [GOC:TermGenie] synonym: "down-regulation of TPK I" RELATED [GOC:TermGenie] synonym: "down-regulation of TPK II" RELATED [GOC:TermGenie] synonym: "down-regulation of TTK" RELATED [GOC:TermGenie] synonym: "downregulation of [Tau protein] kinase activity" EXACT [GOC:TermGenie] synonym: "downregulation of brain protein kinase PK40erk activity" NARROW [GOC:TermGenie] synonym: "downregulation of cdk5/p20" RELATED [GOC:TermGenie] synonym: "downregulation of CDK5/p23" RELATED [GOC:TermGenie] synonym: "downregulation of glycogen synthase kinase-3beta activity" EXACT [GOC:TermGenie] synonym: "downregulation of GSK" RELATED [GOC:TermGenie] synonym: "downregulation of protein tau kinase activity" EXACT [GOC:TermGenie] synonym: "downregulation of STK31" RELATED [GOC:TermGenie] synonym: "downregulation of tau kinase activity" EXACT [GOC:TermGenie] synonym: "downregulation of tau protein kinase activity" EXACT [GOC:TermGenie] synonym: "downregulation of tau-protein kinase activity" EXACT [GOC:TermGenie] synonym: "downregulation of tau-protein kinase I activity" NARROW [GOC:TermGenie] synonym: "downregulation of tau-protein kinase II activity" NARROW [GOC:TermGenie] synonym: "downregulation of tau-tubulin kinase activity" NARROW [GOC:TermGenie] synonym: "downregulation of TPK" RELATED [GOC:TermGenie] synonym: "downregulation of TPK I" RELATED [GOC:TermGenie] synonym: "downregulation of TPK II" RELATED [GOC:TermGenie] synonym: "downregulation of TTK" RELATED [GOC:TermGenie] synonym: "inhibition of [Tau protein] kinase activity" NARROW [GOC:TermGenie] synonym: "inhibition of brain protein kinase PK40erk activity" NARROW [GOC:TermGenie] synonym: "inhibition of cdk5/p20" RELATED [GOC:TermGenie] synonym: "inhibition of CDK5/p23" RELATED [GOC:TermGenie] synonym: "inhibition of glycogen synthase kinase-3beta activity" NARROW [GOC:TermGenie] synonym: "inhibition of GSK" RELATED [GOC:TermGenie] synonym: "inhibition of protein tau kinase activity" NARROW [GOC:TermGenie] synonym: "inhibition of STK31" RELATED [GOC:TermGenie] synonym: "inhibition of tau kinase activity" NARROW [GOC:TermGenie] synonym: "inhibition of tau protein kinase activity" NARROW [GOC:TermGenie] synonym: "inhibition of tau-protein kinase activity" NARROW [GOC:TermGenie] synonym: "inhibition of tau-protein kinase I activity" NARROW [GOC:TermGenie] synonym: "inhibition of tau-protein kinase II activity" NARROW [GOC:TermGenie] synonym: "inhibition of tau-tubulin kinase activity" NARROW [GOC:TermGenie] synonym: "inhibition of TPK" RELATED [GOC:TermGenie] synonym: "inhibition of TPK I" RELATED [GOC:TermGenie] synonym: "inhibition of TPK II" RELATED [GOC:TermGenie] synonym: "inhibition of TTK" RELATED [GOC:TermGenie] synonym: "negative regulation of [Tau protein] kinase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of brain protein kinase PK40erk activity" NARROW [GOC:TermGenie] synonym: "negative regulation of cdk5/p20" RELATED [GOC:TermGenie] synonym: "negative regulation of CDK5/p23" RELATED [GOC:TermGenie] synonym: "negative regulation of glycogen synthase kinase-3beta activity" EXACT [GOC:TermGenie] synonym: "negative regulation of GSK" RELATED [GOC:TermGenie] synonym: "negative regulation of protein tau kinase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of STK31" RELATED [GOC:TermGenie] synonym: "negative regulation of tau kinase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of tau protein kinase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of tau-protein kinase I activity" NARROW [GOC:TermGenie] synonym: "negative regulation of tau-protein kinase II activity" NARROW [GOC:TermGenie] synonym: "negative regulation of tau-tubulin kinase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of TPK" RELATED [GOC:TermGenie] synonym: "negative regulation of TPK I" RELATED [GOC:TermGenie] synonym: "negative regulation of TPK II" RELATED [GOC:TermGenie] synonym: "negative regulation of TTK" RELATED [GOC:TermGenie] is_a: GO:0071901 ! negative regulation of protein serine/threonine kinase activity is_a: GO:1902947 ! regulation of tau-protein kinase activity created_by: sjp creation_date: 2014-05-02T08:43:32Z [Term] id: GO:1902960 name: negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process." [GO_REF:0000059, GOC:sjp, GOC:TermGenie, PMID:24577224] subset: gocheck_obsoletion_candidate synonym: "down regulation of aspartate protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of aspartate protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of aspartate protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of aspartate protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "down regulation of aspartate protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of aspartate protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "down regulation of aspartic endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of aspartic endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of aspartic protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of aspartic protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of aspartic protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of aspartic protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "down regulation of aspartic protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of aspartic protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "down regulation of aspartic-type endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of aspartic-type endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of aspartyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of aspartyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of aspartyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "down regulation of aspartyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of aspartyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of carboxyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of carboxyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of carboxyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "down regulation of carboxyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of carboxyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartate protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartate protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartate protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartate protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartate protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartate protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartic endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartic endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartic protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartic protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartic protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartic protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartic protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartic protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartic-type endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartic-type endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of aspartyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of carboxyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of carboxyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of carboxyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of carboxyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of carboxyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of aspartate protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of aspartate protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of aspartate protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of aspartate protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "downregulation of aspartate protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of aspartate protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "downregulation of aspartic endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of aspartic endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of aspartic protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of aspartic protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of aspartic protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of aspartic protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "downregulation of aspartic protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of aspartic protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "downregulation of aspartic-type endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of aspartic-type endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of aspartyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of aspartyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of aspartyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of aspartyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "downregulation of aspartyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of aspartyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of carboxyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of carboxyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of carboxyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of carboxyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "downregulation of carboxyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of carboxyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "inhibition of aspartate protease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] synonym: "inhibition of aspartate protease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of aspartate protease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of aspartate protease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] synonym: "inhibition of aspartate protease activity involved in APP catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of aspartate protease activity involved in APP catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of aspartic endopeptidase activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] synonym: "inhibition of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of aspartic endopeptidase activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of aspartic endopeptidase activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] synonym: "inhibition of aspartic endopeptidase activity involved in APP catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of aspartic endopeptidase activity involved in APP catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of aspartic protease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] synonym: "inhibition of aspartic protease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of aspartic protease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of aspartic protease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] synonym: "inhibition of aspartic protease activity involved in APP catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of aspartic protease activity involved in APP catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] synonym: "inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] synonym: "inhibition of aspartic-type endopeptidase activity involved in APP catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of aspartic-type endopeptidase activity involved in APP catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of aspartyl protease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] synonym: "inhibition of aspartyl protease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of aspartyl protease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of aspartyl protease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] synonym: "inhibition of aspartyl protease activity involved in APP catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of aspartyl protease activity involved in APP catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of carboxyl protease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] synonym: "inhibition of carboxyl protease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of carboxyl protease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of carboxyl protease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] synonym: "inhibition of carboxyl protease activity involved in APP catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of carboxyl protease activity involved in APP catabolism" NARROW [GOC:TermGenie] synonym: "negative regulation of aspartate protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartate protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartate protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartate protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartate protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartate protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartic endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartic endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartic protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartic protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartic protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartic protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartic protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartic protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartic-type endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartic-type endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "negative regulation of aspartyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of carboxyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "negative regulation of carboxyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of carboxyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "negative regulation of carboxyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "negative regulation of carboxyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] is_a: GO:0010951 ! negative regulation of endopeptidase activity created_by: sjp creation_date: 2014-05-06T09:07:11Z [Term] id: GO:1902961 name: positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process." [GO_REF:0000059, GOC:sjp, GOC:TermGenie, PMID:24577224] subset: gocheck_obsoletion_candidate synonym: "activation of aspartate protease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] synonym: "activation of aspartate protease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] synonym: "activation of aspartate protease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] synonym: "activation of aspartate protease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] synonym: "activation of aspartate protease activity involved in APP catabolic process" NARROW [GOC:TermGenie] synonym: "activation of aspartate protease activity involved in APP catabolism" NARROW [GOC:TermGenie] synonym: "activation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] synonym: "activation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] synonym: "activation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] synonym: "activation of aspartic endopeptidase activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] synonym: "activation of aspartic endopeptidase activity involved in APP catabolic process" NARROW [GOC:TermGenie] synonym: "activation of aspartic endopeptidase activity involved in APP catabolism" NARROW [GOC:TermGenie] synonym: "activation of aspartic protease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] synonym: "activation of aspartic protease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] synonym: "activation of aspartic protease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] synonym: "activation of aspartic protease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] synonym: "activation of aspartic protease activity involved in APP catabolic process" NARROW [GOC:TermGenie] synonym: "activation of aspartic protease activity involved in APP catabolism" NARROW [GOC:TermGenie] synonym: "activation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] synonym: "activation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] synonym: "activation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] synonym: "activation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] synonym: "activation of aspartic-type endopeptidase activity involved in APP catabolic process" NARROW [GOC:TermGenie] synonym: "activation of aspartic-type endopeptidase activity involved in APP catabolism" NARROW [GOC:TermGenie] synonym: "activation of aspartyl protease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] synonym: "activation of aspartyl protease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] synonym: "activation of aspartyl protease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] synonym: "activation of aspartyl protease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] synonym: "activation of aspartyl protease activity involved in APP catabolic process" NARROW [GOC:TermGenie] synonym: "activation of aspartyl protease activity involved in APP catabolism" NARROW [GOC:TermGenie] synonym: "activation of carboxyl protease activity involved in amyloid precursor protein breakdown" NARROW [GOC:TermGenie] synonym: "activation of carboxyl protease activity involved in amyloid precursor protein catabolic process" NARROW [GOC:TermGenie] synonym: "activation of carboxyl protease activity involved in amyloid precursor protein catabolism" NARROW [GOC:TermGenie] synonym: "activation of carboxyl protease activity involved in amyloid precursor protein degradation" NARROW [GOC:TermGenie] synonym: "activation of carboxyl protease activity involved in APP catabolic process" NARROW [GOC:TermGenie] synonym: "activation of carboxyl protease activity involved in APP catabolism" NARROW [GOC:TermGenie] synonym: "positive regulation of aspartate protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartate protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartate protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartate protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartate protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartate protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartic endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartic endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartic protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartic protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartic protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartic protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartic protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartic protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartic-type endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartic-type endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "positive regulation of aspartyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of carboxyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "positive regulation of carboxyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of carboxyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "positive regulation of carboxyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "positive regulation of carboxyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of aspartate protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of aspartate protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of aspartate protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of aspartate protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "up regulation of aspartate protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of aspartate protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "up regulation of aspartic endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of aspartic endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of aspartic protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of aspartic protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of aspartic protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of aspartic protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "up regulation of aspartic protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of aspartic protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "up regulation of aspartic-type endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of aspartic-type endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of aspartyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of aspartyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of aspartyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "up regulation of aspartyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of aspartyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of carboxyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of carboxyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of carboxyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "up regulation of carboxyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of carboxyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartate protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartate protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartate protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartate protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartate protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartate protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartic endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartic endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartic protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartic protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartic protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartic protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartic protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartic protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartic-type endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartic-type endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of carboxyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of carboxyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of carboxyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of carboxyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of carboxyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of aspartate protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of aspartate protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of aspartate protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of aspartate protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "upregulation of aspartate protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of aspartate protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "upregulation of aspartic endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of aspartic endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of aspartic protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of aspartic protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of aspartic protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of aspartic protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "upregulation of aspartic protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of aspartic protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "upregulation of aspartic-type endopeptidase activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of aspartic-type endopeptidase activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of aspartyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of aspartyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of aspartyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of aspartyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "upregulation of aspartyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of aspartyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of carboxyl protease activity involved in amyloid precursor protein breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of carboxyl protease activity involved in amyloid precursor protein catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of carboxyl protease activity involved in amyloid precursor protein catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of carboxyl protease activity involved in amyloid precursor protein degradation" EXACT [GOC:TermGenie] synonym: "upregulation of carboxyl protease activity involved in APP catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of carboxyl protease activity involved in APP catabolism" EXACT [GOC:TermGenie] is_a: GO:0010950 ! positive regulation of endopeptidase activity is_a: GO:1905247 ! positive regulation of aspartic-type peptidase activity created_by: sjp creation_date: 2014-05-06T09:07:17Z [Term] id: GO:1903007 name: positive regulation of Lys63-specific deubiquitinase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of Lys63-specific deubiquitinase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:22970133] subset: gocheck_obsoletion_candidate synonym: "activation of Lys63-specific deubiquitinase activity" NARROW [GOC:TermGenie] synonym: "up regulation of Lys63-specific deubiquitinase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of Lys63-specific deubiquitinase activity" EXACT [GOC:TermGenie] synonym: "upregulation of Lys63-specific deubiquitinase activity" EXACT [GOC:TermGenie] is_a: GO:0010952 ! positive regulation of peptidase activity is_a: GO:0031401 ! positive regulation of protein modification process created_by: bf creation_date: 2014-05-12T15:47:35Z [Term] id: GO:1903016 name: negative regulation of exo-alpha-sialidase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of exo-alpha-sialidase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079] comment: human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) demonstrated in Figure 4A PMID:23544079, (IDA) subset: gocheck_obsoletion_candidate synonym: "down regulation of acetylneuraminidase activity" EXACT [GOC:TermGenie] synonym: "down regulation of acetylneuraminyl hydrolase activity" EXACT [GOC:TermGenie] synonym: "down regulation of alpha-neuraminidase activity" EXACT [GOC:TermGenie] synonym: "down regulation of exo-alpha-sialidase activity" EXACT [GOC:TermGenie] synonym: "down regulation of N-acylneuraminate glycohydrolase activity" EXACT [GOC:TermGenie] synonym: "down regulation of neuraminidase activity" EXACT [GOC:TermGenie] synonym: "down regulation of sialidase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylneuraminidase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylneuraminyl hydrolase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of alpha-neuraminidase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of exo-alpha-sialidase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of N-acylneuraminate glycohydrolase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of neuraminidase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of sialidase activity" EXACT [GOC:TermGenie] synonym: "downregulation of acetylneuraminidase activity" EXACT [GOC:TermGenie] synonym: "downregulation of acetylneuraminyl hydrolase activity" EXACT [GOC:TermGenie] synonym: "downregulation of alpha-neuraminidase activity" EXACT [GOC:TermGenie] synonym: "downregulation of exo-alpha-sialidase activity" EXACT [GOC:TermGenie] synonym: "downregulation of N-acylneuraminate glycohydrolase activity" EXACT [GOC:TermGenie] synonym: "downregulation of neuraminidase activity" EXACT [GOC:TermGenie] synonym: "downregulation of sialidase activity" EXACT [GOC:TermGenie] synonym: "inhibition of acetylneuraminidase activity" NARROW [GOC:TermGenie] synonym: "inhibition of acetylneuraminyl hydrolase activity" NARROW [GOC:TermGenie] synonym: "inhibition of alpha-neuraminidase activity" NARROW [GOC:TermGenie] synonym: "inhibition of exo-alpha-sialidase activity" NARROW [GOC:TermGenie] synonym: "inhibition of N-acylneuraminate glycohydrolase activity" NARROW [GOC:TermGenie] synonym: "inhibition of neuraminidase activity" NARROW [GOC:TermGenie] synonym: "inhibition of sialidase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of acetylneuraminidase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of acetylneuraminyl hydrolase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of alpha-neuraminidase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of N-acylneuraminate glycohydrolase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of neuraminidase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of sialidase activity" EXACT [GOC:TermGenie] is_a: GO:0051346 ! negative regulation of hydrolase activity created_by: rl creation_date: 2014-05-14T18:15:17Z [Term] id: GO:1903017 name: positive regulation of exo-alpha-sialidase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of exo-alpha-sialidase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079] comment: human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) demonstrated in Figure 4A PMID:23544079, (IDA) subset: gocheck_obsoletion_candidate synonym: "activation of acetylneuraminidase activity" NARROW [GOC:TermGenie] synonym: "activation of acetylneuraminyl hydrolase activity" NARROW [GOC:TermGenie] synonym: "activation of alpha-neuraminidase activity" NARROW [GOC:TermGenie] synonym: "activation of exo-alpha-sialidase activity" NARROW [GOC:TermGenie] synonym: "activation of N-acylneuraminate glycohydrolase activity" NARROW [GOC:TermGenie] synonym: "activation of neuraminidase activity" NARROW [GOC:TermGenie] synonym: "activation of sialidase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of acetylneuraminidase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of acetylneuraminyl hydrolase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of alpha-neuraminidase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of N-acylneuraminate glycohydrolase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of neuraminidase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of sialidase activity" EXACT [GOC:TermGenie] synonym: "up regulation of acetylneuraminidase activity" EXACT [GOC:TermGenie] synonym: "up regulation of acetylneuraminyl hydrolase activity" EXACT [GOC:TermGenie] synonym: "up regulation of alpha-neuraminidase activity" EXACT [GOC:TermGenie] synonym: "up regulation of exo-alpha-sialidase activity" EXACT [GOC:TermGenie] synonym: "up regulation of N-acylneuraminate glycohydrolase activity" EXACT [GOC:TermGenie] synonym: "up regulation of neuraminidase activity" EXACT [GOC:TermGenie] synonym: "up regulation of sialidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylneuraminidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylneuraminyl hydrolase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of alpha-neuraminidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of exo-alpha-sialidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of N-acylneuraminate glycohydrolase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of neuraminidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of sialidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of acetylneuraminidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of acetylneuraminyl hydrolase activity" EXACT [GOC:TermGenie] synonym: "upregulation of alpha-neuraminidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of exo-alpha-sialidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of N-acylneuraminate glycohydrolase activity" EXACT [GOC:TermGenie] synonym: "upregulation of neuraminidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of sialidase activity" EXACT [GOC:TermGenie] is_a: GO:0051345 ! positive regulation of hydrolase activity created_by: rl creation_date: 2014-05-14T18:15:23Z [Term] id: GO:1903048 name: regulation of acetylcholine-gated cation channel activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of acetylcholine-gated cation channel activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21718690] subset: gocheck_obsoletion_candidate is_a: GO:0098962 ! regulation of postsynaptic neurotransmitter receptor activity is_a: GO:2001257 ! regulation of cation channel activity created_by: bf creation_date: 2014-05-22T14:46:53Z [Term] id: GO:1903059 name: regulation of protein lipidation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein lipidation." [GO_REF:0000058, GOC:rph, GOC:TermGenie, PMID:21909394] subset: gocheck_obsoletion_candidate synonym: "regulation of lipid:protein modification" EXACT [GOC:TermGenie] synonym: "regulation of protein amino acid lipidation" EXACT [GOC:TermGenie] relationship: regulates GO:0006497 ! protein lipidation created_by: rph creation_date: 2014-05-28T13:21:18Z [Term] id: GO:1903060 name: negative regulation of protein lipidation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein lipidation." [GO_REF:0000058, GOC:rph, GOC:TermGenie, PMID:21909394] subset: gocheck_obsoletion_candidate synonym: "down regulation of lipid:protein modification" EXACT [GOC:TermGenie] synonym: "down regulation of protein amino acid lipidation" EXACT [GOC:TermGenie] synonym: "down regulation of protein lipidation" EXACT [GOC:TermGenie] synonym: "down-regulation of lipid:protein modification" EXACT [GOC:TermGenie] synonym: "down-regulation of protein amino acid lipidation" EXACT [GOC:TermGenie] synonym: "down-regulation of protein lipidation" EXACT [GOC:TermGenie] synonym: "downregulation of lipid:protein modification" EXACT [GOC:TermGenie] synonym: "downregulation of protein amino acid lipidation" EXACT [GOC:TermGenie] synonym: "downregulation of protein lipidation" EXACT [GOC:TermGenie] synonym: "inhibition of lipid:protein modification" NARROW [GOC:TermGenie] synonym: "inhibition of protein amino acid lipidation" NARROW [GOC:TermGenie] synonym: "inhibition of protein lipidation" NARROW [GOC:TermGenie] synonym: "negative regulation of lipid:protein modification" EXACT [GOC:TermGenie] synonym: "negative regulation of protein amino acid lipidation" EXACT [GOC:TermGenie] is_a: GO:0031400 ! negative regulation of protein modification process is_a: GO:1903059 ! regulation of protein lipidation relationship: negatively_regulates GO:0006497 ! protein lipidation created_by: rph creation_date: 2014-05-28T13:21:25Z [Term] id: GO:1903061 name: positive regulation of protein lipidation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein lipidation." [GO_REF:0000058, GOC:rph, GOC:TermGenie, PMID:21909394] subset: gocheck_obsoletion_candidate synonym: "activation of lipid:protein modification" NARROW [GOC:TermGenie] synonym: "activation of protein amino acid lipidation" NARROW [GOC:TermGenie] synonym: "activation of protein lipidation" NARROW [GOC:TermGenie] synonym: "positive regulation of lipid:protein modification" EXACT [GOC:TermGenie] synonym: "positive regulation of protein amino acid lipidation" EXACT [GOC:TermGenie] synonym: "up regulation of lipid:protein modification" EXACT [GOC:TermGenie] synonym: "up regulation of protein amino acid lipidation" EXACT [GOC:TermGenie] synonym: "up regulation of protein lipidation" EXACT [GOC:TermGenie] synonym: "up-regulation of lipid:protein modification" EXACT [GOC:TermGenie] synonym: "up-regulation of protein amino acid lipidation" EXACT [GOC:TermGenie] synonym: "up-regulation of protein lipidation" EXACT [GOC:TermGenie] synonym: "upregulation of lipid:protein modification" EXACT [GOC:TermGenie] synonym: "upregulation of protein amino acid lipidation" EXACT [GOC:TermGenie] synonym: "upregulation of protein lipidation" EXACT [GOC:TermGenie] is_a: GO:0031401 ! positive regulation of protein modification process is_a: GO:1903059 ! regulation of protein lipidation relationship: positively_regulates GO:0006497 ! protein lipidation created_by: rph creation_date: 2014-05-28T13:21:31Z [Term] id: GO:1903125 name: negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation namespace: biological_process def: "A peptidyl-threonine phosphorylation that results in negative regulation of thioredoxin peroxidase activity." [GO_REF:0000063, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21850687] subset: gocheck_obsoletion_candidate synonym: "negative regulation of thiol peroxidase activity by peptidyl-threonine phosphorylation" EXACT [GOC:TermGenie] synonym: "negative regulation of TPx activity by peptidyl-threonine phosphorylation" EXACT [GOC:TermGenie] synonym: "negative regulation of TrxPx activity by peptidyl-threonine phosphorylation" EXACT [GOC:TermGenie] is_a: GO:0018107 ! peptidyl-threonine phosphorylation created_by: bf creation_date: 2014-06-24T08:47:25Z [Term] id: GO:1903281 name: positive regulation of calcium:sodium antiporter activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of calcium:sodium antiporter activity." [GO_REF:0000059, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:19683723] subset: gocheck_obsoletion_candidate synonym: "activation of calcium:sodium antiporter activity" NARROW [GOC:TermGenie] synonym: "activation of mitochondrial sodium/calcium ion exchange" RELATED [GOC:TermGenie] synonym: "activation of sodium/calcium exchanger" NARROW [GOC:TermGenie] synonym: "activation of sodium:calcium exchange" RELATED [GOC:TermGenie] synonym: "positive regulation of mitochondrial sodium/calcium ion exchange" RELATED [GOC:TermGenie] synonym: "positive regulation of sodium/calcium exchanger" EXACT [GOC:TermGenie] synonym: "positive regulation of sodium:calcium exchange" RELATED [GOC:TermGenie] synonym: "up regulation of calcium:sodium antiporter activity" EXACT [GOC:TermGenie] synonym: "up regulation of mitochondrial sodium/calcium ion exchange" RELATED [GOC:TermGenie] synonym: "up regulation of sodium/calcium exchanger" EXACT [GOC:TermGenie] synonym: "up regulation of sodium:calcium exchange" RELATED [GOC:TermGenie] synonym: "up-regulation of calcium:sodium antiporter activity" EXACT [GOC:TermGenie] synonym: "up-regulation of mitochondrial sodium/calcium ion exchange" RELATED [GOC:TermGenie] synonym: "up-regulation of sodium/calcium exchanger" EXACT [GOC:TermGenie] synonym: "up-regulation of sodium:calcium exchange" RELATED [GOC:TermGenie] synonym: "upregulation of calcium:sodium antiporter activity" EXACT [GOC:TermGenie] synonym: "upregulation of mitochondrial sodium/calcium ion exchange" RELATED [GOC:TermGenie] synonym: "upregulation of sodium/calcium exchanger" EXACT [GOC:TermGenie] synonym: "upregulation of sodium:calcium exchange" RELATED [GOC:TermGenie] is_a: GO:1901021 ! positive regulation of calcium ion transmembrane transporter activity is_a: GO:2000651 ! positive regulation of sodium ion transmembrane transporter activity created_by: rl creation_date: 2014-08-11T12:53:47Z [Term] id: GO:1903282 name: regulation of glutathione peroxidase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glutathione peroxidase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie] subset: gocheck_obsoletion_candidate synonym: "regulation of glutathione:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "regulation of GSH peroxidase activity" EXACT [GOC:TermGenie] synonym: "regulation of non-selenium glutathione peroxidase activity" NARROW [GOC:TermGenie] synonym: "regulation of reduced glutathione peroxidase activity" EXACT [GOC:TermGenie] synonym: "regulation of selenium-glutathione peroxidase activity" EXACT [GOC:TermGenie] is_a: GO:0051341 ! regulation of oxidoreductase activity created_by: bf creation_date: 2014-08-11T13:14:13Z [Term] id: GO:1903284 name: positive regulation of glutathione peroxidase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of glutathione peroxidase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:23507046] subset: gocheck_obsoletion_candidate synonym: "activation of glutathione peroxidase activity" NARROW [GOC:TermGenie] synonym: "activation of glutathione:hydrogen-peroxide oxidoreductase activity" NARROW [GOC:TermGenie] synonym: "activation of GSH peroxidase activity" NARROW [GOC:TermGenie] synonym: "activation of non-selenium glutathione peroxidase activity" NARROW [GOC:TermGenie] synonym: "activation of reduced glutathione peroxidase activity" NARROW [GOC:TermGenie] synonym: "activation of selenium-glutathione peroxidase activity" NARROW [GOC:TermGenie] synonym: "enhancement of GPX activity" EXACT [PMID:23507046] synonym: "positive regulation of glutathione:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of GSH peroxidase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of non-selenium glutathione peroxidase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of reduced glutathione peroxidase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of selenium-glutathione peroxidase activity" EXACT [GOC:TermGenie] synonym: "up regulation of glutathione peroxidase activity" EXACT [GOC:TermGenie] synonym: "up regulation of glutathione:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "up regulation of GSH peroxidase activity" EXACT [GOC:TermGenie] synonym: "up regulation of non-selenium glutathione peroxidase activity" NARROW [GOC:TermGenie] synonym: "up regulation of reduced glutathione peroxidase activity" EXACT [GOC:TermGenie] synonym: "up regulation of selenium-glutathione peroxidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of glutathione peroxidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of glutathione:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of GSH peroxidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of non-selenium glutathione peroxidase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of reduced glutathione peroxidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of selenium-glutathione peroxidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of glutathione peroxidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of glutathione:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "upregulation of GSH peroxidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of non-selenium glutathione peroxidase activity" NARROW [GOC:TermGenie] synonym: "upregulation of reduced glutathione peroxidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of selenium-glutathione peroxidase activity" EXACT [GOC:TermGenie] is_a: GO:1903282 ! regulation of glutathione peroxidase activity is_a: GO:2000470 ! positive regulation of peroxidase activity created_by: bf creation_date: 2014-08-11T13:14:30Z [Term] id: GO:1903300 name: negative regulation of hexokinase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hexokinase activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:15804508] subset: gocheck_obsoletion_candidate synonym: "down regulation of ATP-dependent hexokinase activity" EXACT [GOC:TermGenie] synonym: "down regulation of ATP:D-hexose 6-phosphotransferase activity" EXACT [GOC:TermGenie] synonym: "down regulation of glucose ATP phosphotransferase activity" EXACT [GOC:TermGenie] synonym: "down regulation of hexokinase (phosphorylating)" EXACT [GOC:TermGenie] synonym: "down regulation of hexokinase activity" EXACT [GOC:TermGenie] synonym: "down regulation of hexokinase D" RELATED [GOC:TermGenie] synonym: "down regulation of hexokinase type I activity" NARROW [GOC:TermGenie] synonym: "down regulation of hexokinase type II activity" NARROW [GOC:TermGenie] synonym: "down regulation of hexokinase type III activity" NARROW [GOC:TermGenie] synonym: "down regulation of hexokinase type IV" RELATED [GOC:TermGenie] synonym: "down regulation of hexokinase type IV (glucokinase) activity" NARROW [GOC:TermGenie] synonym: "down regulation of hexokinase type IV glucokinase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of ATP-dependent hexokinase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of ATP:D-hexose 6-phosphotransferase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of glucose ATP phosphotransferase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of hexokinase (phosphorylating)" EXACT [GOC:TermGenie] synonym: "down-regulation of hexokinase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of hexokinase D" RELATED [GOC:TermGenie] synonym: "down-regulation of hexokinase type I activity" NARROW [GOC:TermGenie] synonym: "down-regulation of hexokinase type II activity" NARROW [GOC:TermGenie] synonym: "down-regulation of hexokinase type III activity" NARROW [GOC:TermGenie] synonym: "down-regulation of hexokinase type IV" RELATED [GOC:TermGenie] synonym: "down-regulation of hexokinase type IV (glucokinase) activity" NARROW [GOC:TermGenie] synonym: "down-regulation of hexokinase type IV glucokinase activity" EXACT [GOC:TermGenie] synonym: "downregulation of ATP-dependent hexokinase activity" EXACT [GOC:TermGenie] synonym: "downregulation of ATP:D-hexose 6-phosphotransferase activity" EXACT [GOC:TermGenie] synonym: "downregulation of glucose ATP phosphotransferase activity" EXACT [GOC:TermGenie] synonym: "downregulation of hexokinase (phosphorylating)" EXACT [GOC:TermGenie] synonym: "downregulation of hexokinase activity" EXACT [GOC:TermGenie] synonym: "downregulation of hexokinase D" RELATED [GOC:TermGenie] synonym: "downregulation of hexokinase type I activity" NARROW [GOC:TermGenie] synonym: "downregulation of hexokinase type II activity" NARROW [GOC:TermGenie] synonym: "downregulation of hexokinase type III activity" NARROW [GOC:TermGenie] synonym: "downregulation of hexokinase type IV" RELATED [GOC:TermGenie] synonym: "downregulation of hexokinase type IV (glucokinase) activity" NARROW [GOC:TermGenie] synonym: "downregulation of hexokinase type IV glucokinase activity" EXACT [GOC:TermGenie] synonym: "inhibition of ATP-dependent hexokinase activity" NARROW [GOC:TermGenie] synonym: "inhibition of ATP:D-hexose 6-phosphotransferase activity" NARROW [GOC:TermGenie] synonym: "inhibition of glucose ATP phosphotransferase activity" NARROW [GOC:TermGenie] synonym: "inhibition of hexokinase (phosphorylating)" NARROW [GOC:TermGenie] synonym: "inhibition of hexokinase activity" NARROW [GOC:TermGenie] synonym: "inhibition of hexokinase D" RELATED [GOC:TermGenie] synonym: "inhibition of hexokinase type I activity" NARROW [GOC:TermGenie] synonym: "inhibition of hexokinase type II activity" NARROW [GOC:TermGenie] synonym: "inhibition of hexokinase type III activity" NARROW [GOC:TermGenie] synonym: "inhibition of hexokinase type IV" RELATED [GOC:TermGenie] synonym: "inhibition of hexokinase type IV (glucokinase) activity" NARROW [GOC:TermGenie] synonym: "inhibition of hexokinase type IV glucokinase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of ATP-dependent hexokinase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of ATP:D-hexose 6-phosphotransferase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of glucose ATP phosphotransferase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of hexokinase (phosphorylating)" EXACT [GOC:TermGenie] synonym: "negative regulation of hexokinase D" RELATED [GOC:TermGenie] synonym: "negative regulation of hexokinase type I activity" NARROW [GOC:TermGenie] synonym: "negative regulation of hexokinase type II activity" NARROW [GOC:TermGenie] synonym: "negative regulation of hexokinase type III activity" NARROW [GOC:TermGenie] synonym: "negative regulation of hexokinase type IV" RELATED [GOC:TermGenie] synonym: "negative regulation of hexokinase type IV (glucokinase) activity" NARROW [GOC:TermGenie] synonym: "negative regulation of hexokinase type IV glucokinase activity" EXACT [GOC:TermGenie] is_a: GO:0033673 ! negative regulation of kinase activity created_by: mr creation_date: 2014-08-15T23:18:01Z [Term] id: GO:1903301 name: positive regulation of hexokinase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hexokinase activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:15804508] subset: gocheck_obsoletion_candidate synonym: "activation of ATP-dependent hexokinase activity" NARROW [GOC:TermGenie] synonym: "activation of ATP:D-hexose 6-phosphotransferase activity" NARROW [GOC:TermGenie] synonym: "activation of glucose ATP phosphotransferase activity" NARROW [GOC:TermGenie] synonym: "activation of hexokinase (phosphorylating)" NARROW [GOC:TermGenie] synonym: "activation of hexokinase activity" NARROW [GOC:TermGenie] synonym: "activation of hexokinase D" RELATED [GOC:TermGenie] synonym: "activation of hexokinase type I activity" NARROW [GOC:TermGenie] synonym: "activation of hexokinase type II activity" NARROW [GOC:TermGenie] synonym: "activation of hexokinase type III activity" NARROW [GOC:TermGenie] synonym: "activation of hexokinase type IV" RELATED [GOC:TermGenie] synonym: "activation of hexokinase type IV (glucokinase) activity" NARROW [GOC:TermGenie] synonym: "activation of hexokinase type IV glucokinase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of ATP-dependent hexokinase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of ATP:D-hexose 6-phosphotransferase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of glucose ATP phosphotransferase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of hexokinase (phosphorylating)" EXACT [GOC:TermGenie] synonym: "positive regulation of hexokinase D" RELATED [GOC:TermGenie] synonym: "positive regulation of hexokinase type I activity" NARROW [GOC:TermGenie] synonym: "positive regulation of hexokinase type II activity" NARROW [GOC:TermGenie] synonym: "positive regulation of hexokinase type III activity" NARROW [GOC:TermGenie] synonym: "positive regulation of hexokinase type IV" RELATED [GOC:TermGenie] synonym: "positive regulation of hexokinase type IV (glucokinase) activity" NARROW [GOC:TermGenie] synonym: "positive regulation of hexokinase type IV glucokinase activity" EXACT [GOC:TermGenie] synonym: "up regulation of ATP-dependent hexokinase activity" EXACT [GOC:TermGenie] synonym: "up regulation of ATP:D-hexose 6-phosphotransferase activity" EXACT [GOC:TermGenie] synonym: "up regulation of glucose ATP phosphotransferase activity" EXACT [GOC:TermGenie] synonym: "up regulation of hexokinase (phosphorylating)" EXACT [GOC:TermGenie] synonym: "up regulation of hexokinase activity" EXACT [GOC:TermGenie] synonym: "up regulation of hexokinase D" RELATED [GOC:TermGenie] synonym: "up regulation of hexokinase type I activity" NARROW [GOC:TermGenie] synonym: "up regulation of hexokinase type II activity" NARROW [GOC:TermGenie] synonym: "up regulation of hexokinase type III activity" NARROW [GOC:TermGenie] synonym: "up regulation of hexokinase type IV" RELATED [GOC:TermGenie] synonym: "up regulation of hexokinase type IV (glucokinase) activity" NARROW [GOC:TermGenie] synonym: "up regulation of hexokinase type IV glucokinase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of ATP-dependent hexokinase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of ATP:D-hexose 6-phosphotransferase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of glucose ATP phosphotransferase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of hexokinase (phosphorylating)" EXACT [GOC:TermGenie] synonym: "up-regulation of hexokinase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of hexokinase D" RELATED [GOC:TermGenie] synonym: "up-regulation of hexokinase type I activity" NARROW [GOC:TermGenie] synonym: "up-regulation of hexokinase type II activity" NARROW [GOC:TermGenie] synonym: "up-regulation of hexokinase type III activity" NARROW [GOC:TermGenie] synonym: "up-regulation of hexokinase type IV" RELATED [GOC:TermGenie] synonym: "up-regulation of hexokinase type IV (glucokinase) activity" NARROW [GOC:TermGenie] synonym: "up-regulation of hexokinase type IV glucokinase activity" EXACT [GOC:TermGenie] synonym: "upregulation of ATP-dependent hexokinase activity" EXACT [GOC:TermGenie] synonym: "upregulation of ATP:D-hexose 6-phosphotransferase activity" EXACT [GOC:TermGenie] synonym: "upregulation of glucose ATP phosphotransferase activity" EXACT [GOC:TermGenie] synonym: "upregulation of hexokinase (phosphorylating)" EXACT [GOC:TermGenie] synonym: "upregulation of hexokinase activity" EXACT [GOC:TermGenie] synonym: "upregulation of hexokinase D" RELATED [GOC:TermGenie] synonym: "upregulation of hexokinase type I activity" NARROW [GOC:TermGenie] synonym: "upregulation of hexokinase type II activity" NARROW [GOC:TermGenie] synonym: "upregulation of hexokinase type III activity" NARROW [GOC:TermGenie] synonym: "upregulation of hexokinase type IV" RELATED [GOC:TermGenie] synonym: "upregulation of hexokinase type IV (glucokinase) activity" NARROW [GOC:TermGenie] synonym: "upregulation of hexokinase type IV glucokinase activity" EXACT [GOC:TermGenie] is_a: GO:0033674 ! positive regulation of kinase activity created_by: mr creation_date: 2014-08-15T23:18:09Z [Term] id: GO:1903302 name: regulation of pyruvate kinase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of pyruvate kinase activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:15804508] subset: gocheck_obsoletion_candidate synonym: "regulation of ATP:pyruvate 2-O-phosphotransferase activity" EXACT [GOC:TermGenie] synonym: "regulation of phosphoenol transphosphorylase activity" EXACT [GOC:TermGenie] synonym: "regulation of phosphoenolpyruvate kinase activity" EXACT [GOC:TermGenie] is_a: GO:0051338 ! regulation of transferase activity created_by: mr creation_date: 2014-08-15T23:25:51Z [Term] id: GO:1903406 name: regulation of P-type sodium:potassium-exchanging transporter activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sodium:potassium-exchanging ATPase activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:8160880] subset: gocheck_obsoletion_candidate synonym: "regulation of (Na+ + K+)-activated ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of (Na+ + K+)-ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of ATP phosphohydrolase (Na+/K+-exchanging)" EXACT [GOC:TermGenie] synonym: "regulation of Na(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of Na(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of Na+,K+ pump" RELATED [GOC:TermGenie] synonym: "regulation of Na+,K+-ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of Na+/K+-ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of Na+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of Na,K-activated ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of Na,K-pump" RELATED [GOC:TermGenie] synonym: "regulation of sodium pump" BROAD [GOC:TermGenie] synonym: "regulation of sodium/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of sodium/potassium-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of sodium:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of sodium:potassium-exchanging ATPase activity" EXACT [] is_a: GO:0043462 ! regulation of ATP-dependent activity is_a: GO:1901016 ! regulation of potassium ion transmembrane transporter activity is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity created_by: mr creation_date: 2014-09-02T19:45:08Z [Term] id: GO:1903407 name: negative regulation of P-type sodium:potassium-exchanging transporter activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of sodium:potassium-exchanging ATPase activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:8160880] subset: gocheck_obsoletion_candidate synonym: "down regulation of (Na+ + K+)-activated ATPase activity" EXACT [GOC:TermGenie] synonym: "down regulation of (Na+ + K+)-ATPase activity" EXACT [GOC:TermGenie] synonym: "down regulation of ATP phosphohydrolase (Na+/K+-exchanging)" EXACT [GOC:TermGenie] synonym: "down regulation of Na(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] synonym: "down regulation of Na(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "down regulation of Na+,K+ pump" RELATED [GOC:TermGenie] synonym: "down regulation of Na+,K+-ATPase activity" EXACT [GOC:TermGenie] synonym: "down regulation of Na+/K+-ATPase activity" EXACT [GOC:TermGenie] synonym: "down regulation of Na+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "down regulation of Na,K-activated ATPase activity" EXACT [GOC:TermGenie] synonym: "down regulation of Na,K-pump" RELATED [GOC:TermGenie] synonym: "down regulation of sodium/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "down regulation of sodium/potassium-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "down regulation of sodium:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "down regulation of sodium:potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of (Na+ + K+)-activated ATPase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of (Na+ + K+)-ATPase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of ATP phosphohydrolase (Na+/K+-exchanging)" EXACT [GOC:TermGenie] synonym: "down-regulation of Na(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of Na(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of Na+,K+ pump" RELATED [GOC:TermGenie] synonym: "down-regulation of Na+,K+-ATPase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of Na+/K+-ATPase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of Na+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of Na,K-activated ATPase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of Na,K-pump" RELATED [GOC:TermGenie] synonym: "down-regulation of sodium/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of sodium/potassium-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of sodium:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of sodium:potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "downregulation of (Na+ + K+)-activated ATPase activity" EXACT [GOC:TermGenie] synonym: "downregulation of (Na+ + K+)-ATPase activity" EXACT [GOC:TermGenie] synonym: "downregulation of ATP phosphohydrolase (Na+/K+-exchanging)" EXACT [GOC:TermGenie] synonym: "downregulation of Na(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] synonym: "downregulation of Na(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "downregulation of Na+,K+ pump" RELATED [GOC:TermGenie] synonym: "downregulation of Na+,K+-ATPase activity" EXACT [GOC:TermGenie] synonym: "downregulation of Na+/K+-ATPase activity" EXACT [GOC:TermGenie] synonym: "downregulation of Na+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "downregulation of Na,K-activated ATPase activity" EXACT [GOC:TermGenie] synonym: "downregulation of Na,K-pump" RELATED [GOC:TermGenie] synonym: "downregulation of sodium/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "downregulation of sodium/potassium-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "downregulation of sodium:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "downregulation of sodium:potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "inhibition of (Na+ + K+)-activated ATPase activity" NARROW [GOC:TermGenie] synonym: "inhibition of (Na+ + K+)-ATPase activity" NARROW [GOC:TermGenie] synonym: "inhibition of ATP phosphohydrolase (Na+/K+-exchanging)" NARROW [GOC:TermGenie] synonym: "inhibition of Na(+)/K(+)-ATPase activity" NARROW [GOC:TermGenie] synonym: "inhibition of Na(+)/K(+)-exchanging ATPase activity" NARROW [GOC:TermGenie] synonym: "inhibition of Na+,K+ pump" RELATED [GOC:TermGenie] synonym: "inhibition of Na+,K+-ATPase activity" NARROW [GOC:TermGenie] synonym: "inhibition of Na+/K+-ATPase activity" NARROW [GOC:TermGenie] synonym: "inhibition of Na+/K+-exchanging ATPase activity" NARROW [GOC:TermGenie] synonym: "inhibition of Na,K-activated ATPase activity" NARROW [GOC:TermGenie] synonym: "inhibition of Na,K-pump" RELATED [GOC:TermGenie] synonym: "inhibition of sodium/potassium-exchanging ATPase activity" NARROW [GOC:TermGenie] synonym: "inhibition of sodium/potassium-transporting ATPase activity" NARROW [GOC:TermGenie] synonym: "inhibition of sodium:potassium exchanging ATPase activity" NARROW [GOC:TermGenie] synonym: "inhibition of sodium:potassium-exchanging ATPase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of (Na+ + K+)-activated ATPase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of (Na+ + K+)-ATPase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of ATP phosphohydrolase (Na+/K+-exchanging)" EXACT [GOC:TermGenie] synonym: "negative regulation of Na(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of Na(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of Na+,K+ pump" RELATED [GOC:TermGenie] synonym: "negative regulation of Na+,K+-ATPase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of Na+/K+-ATPase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of Na+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of Na,K-activated ATPase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of Na,K-pump" RELATED [GOC:TermGenie] synonym: "negative regulation of sodium/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of sodium/potassium-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of sodium:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of sodium:potassium-exchanging ATPase activity" EXACT [] is_a: GO:0032780 ! negative regulation of ATP-dependent activity is_a: GO:1901017 ! negative regulation of potassium ion transmembrane transporter activity is_a: GO:1903406 ! regulation of P-type sodium:potassium-exchanging transporter activity is_a: GO:2000650 ! negative regulation of sodium ion transmembrane transporter activity created_by: mr creation_date: 2014-09-02T19:45:16Z [Term] id: GO:1903408 name: positive regulation of P-type sodium:potassium-exchanging transporter activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of sodium:potassium-exchanging ATPase activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:8160880] subset: gocheck_obsoletion_candidate synonym: "activation of (Na+ + K+)-activated ATPase activity" NARROW [GOC:TermGenie] synonym: "activation of (Na+ + K+)-ATPase activity" NARROW [GOC:TermGenie] synonym: "activation of ATP phosphohydrolase (Na+/K+-exchanging)" NARROW [GOC:TermGenie] synonym: "activation of Na(+)/K(+)-ATPase activity" NARROW [GOC:TermGenie] synonym: "activation of Na(+)/K(+)-exchanging ATPase activity" NARROW [GOC:TermGenie] synonym: "activation of Na+,K+ pump" RELATED [GOC:TermGenie] synonym: "activation of Na+,K+-ATPase activity" NARROW [GOC:TermGenie] synonym: "activation of Na+/K+-ATPase activity" NARROW [GOC:TermGenie] synonym: "activation of Na+/K+-exchanging ATPase activity" NARROW [GOC:TermGenie] synonym: "activation of Na,K-activated ATPase activity" NARROW [GOC:TermGenie] synonym: "activation of Na,K-pump" RELATED [GOC:TermGenie] synonym: "activation of sodium/potassium-exchanging ATPase activity" NARROW [GOC:TermGenie] synonym: "activation of sodium/potassium-transporting ATPase activity" NARROW [GOC:TermGenie] synonym: "activation of sodium:potassium exchanging ATPase activity" NARROW [GOC:TermGenie] synonym: "activation of sodium:potassium-exchanging ATPase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of (Na+ + K+)-activated ATPase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of (Na+ + K+)-ATPase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of ATP phosphohydrolase (Na+/K+-exchanging)" EXACT [GOC:TermGenie] synonym: "positive regulation of Na(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of Na(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of Na+,K+ pump" RELATED [GOC:TermGenie] synonym: "positive regulation of Na+,K+-ATPase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of Na+/K+-ATPase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of Na+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of Na,K-activated ATPase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of Na,K-pump" RELATED [GOC:TermGenie] synonym: "positive regulation of sodium/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of sodium/potassium-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of sodium:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of sodium:potassium-exchanging ATPase activity" EXACT [] synonym: "up regulation of (Na+ + K+)-activated ATPase activity" EXACT [GOC:TermGenie] synonym: "up regulation of (Na+ + K+)-ATPase activity" EXACT [GOC:TermGenie] synonym: "up regulation of ATP phosphohydrolase (Na+/K+-exchanging)" EXACT [GOC:TermGenie] synonym: "up regulation of Na(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] synonym: "up regulation of Na(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "up regulation of Na+,K+ pump" RELATED [GOC:TermGenie] synonym: "up regulation of Na+,K+-ATPase activity" EXACT [GOC:TermGenie] synonym: "up regulation of Na+/K+-ATPase activity" EXACT [GOC:TermGenie] synonym: "up regulation of Na+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "up regulation of Na,K-activated ATPase activity" EXACT [GOC:TermGenie] synonym: "up regulation of Na,K-pump" RELATED [GOC:TermGenie] synonym: "up regulation of sodium/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "up regulation of sodium/potassium-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "up regulation of sodium:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "up regulation of sodium:potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of (Na+ + K+)-activated ATPase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of (Na+ + K+)-ATPase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of ATP phosphohydrolase (Na+/K+-exchanging)" EXACT [GOC:TermGenie] synonym: "up-regulation of Na(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of Na(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of Na+,K+ pump" RELATED [GOC:TermGenie] synonym: "up-regulation of Na+,K+-ATPase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of Na+/K+-ATPase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of Na+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of Na,K-activated ATPase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of Na,K-pump" RELATED [GOC:TermGenie] synonym: "up-regulation of sodium/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of sodium/potassium-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of sodium:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of sodium:potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "upregulation of (Na+ + K+)-activated ATPase activity" EXACT [GOC:TermGenie] synonym: "upregulation of (Na+ + K+)-ATPase activity" EXACT [GOC:TermGenie] synonym: "upregulation of ATP phosphohydrolase (Na+/K+-exchanging)" EXACT [GOC:TermGenie] synonym: "upregulation of Na(+)/K(+)-ATPase activity" EXACT [GOC:TermGenie] synonym: "upregulation of Na(+)/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "upregulation of Na+,K+ pump" RELATED [GOC:TermGenie] synonym: "upregulation of Na+,K+-ATPase activity" EXACT [GOC:TermGenie] synonym: "upregulation of Na+/K+-ATPase activity" EXACT [GOC:TermGenie] synonym: "upregulation of Na+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "upregulation of Na,K-activated ATPase activity" EXACT [GOC:TermGenie] synonym: "upregulation of Na,K-pump" RELATED [GOC:TermGenie] synonym: "upregulation of sodium/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "upregulation of sodium/potassium-transporting ATPase activity" EXACT [GOC:TermGenie] synonym: "upregulation of sodium:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "upregulation of sodium:potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] is_a: GO:0032781 ! positive regulation of ATP-dependent activity is_a: GO:1901018 ! positive regulation of potassium ion transmembrane transporter activity is_a: GO:1903406 ! regulation of P-type sodium:potassium-exchanging transporter activity is_a: GO:2000651 ! positive regulation of sodium ion transmembrane transporter activity created_by: mr creation_date: 2014-09-02T19:45:24Z [Term] id: GO:1903547 name: regulation of growth hormone activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of growth hormone activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:3068266] subset: gocheck_obsoletion_candidate synonym: "regulation of GH activity" EXACT [GOC:TermGenie] synonym: "regulation of pituitary growth hormone activity" NARROW [GOC:TermGenie] synonym: "regulation of placental growth hormone activity" NARROW [GOC:TermGenie] is_a: GO:0010469 ! regulation of signaling receptor activity created_by: mr creation_date: 2014-10-20T15:18:36Z [Term] id: GO:1903592 name: positive regulation of lysozyme activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lysozyme activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:23954697] subset: gocheck_obsoletion_candidate synonym: "activation of 1,4-N-acetylmuramidase activity" NARROW [GOC:TermGenie] synonym: "activation of globulin G" RELATED [GOC:TermGenie] synonym: "activation of globulin G1" RELATED [GOC:TermGenie] synonym: "activation of L-7001" RELATED [GOC:TermGenie] synonym: "activation of lysozyme activity" NARROW [GOC:TermGenie] synonym: "activation of lysozyme g" RELATED [GOC:TermGenie] synonym: "activation of mucopeptide glucohydrolase activity" NARROW [GOC:TermGenie] synonym: "activation of mucopeptide N-acetylmuramoylhydrolase activity" NARROW [GOC:TermGenie] synonym: "activation of muramidase activity" NARROW [GOC:TermGenie] synonym: "activation of N,O-diacetylmuramidase activity" NARROW [GOC:TermGenie] synonym: "activation of peptidoglycan N-acetylmuramoylhydrolase activity" NARROW [GOC:TermGenie] synonym: "activation of PR1-lysozyme" RELATED [GOC:TermGenie] synonym: "positive regulation of 1,4-N-acetylmuramidase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of globulin G" RELATED [GOC:TermGenie] synonym: "positive regulation of globulin G1" RELATED [GOC:TermGenie] synonym: "positive regulation of L-7001" RELATED [GOC:TermGenie] synonym: "positive regulation of lysozyme g" RELATED [GOC:TermGenie] synonym: "positive regulation of mucopeptide glucohydrolase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of mucopeptide N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of muramidase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of N,O-diacetylmuramidase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of peptidoglycan N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of PR1-lysozyme" RELATED [GOC:TermGenie] synonym: "up regulation of 1,4-N-acetylmuramidase activity" EXACT [GOC:TermGenie] synonym: "up regulation of globulin G" RELATED [GOC:TermGenie] synonym: "up regulation of globulin G1" RELATED [GOC:TermGenie] synonym: "up regulation of L-7001" RELATED [GOC:TermGenie] synonym: "up regulation of lysozyme activity" EXACT [GOC:TermGenie] synonym: "up regulation of lysozyme g" RELATED [GOC:TermGenie] synonym: "up regulation of mucopeptide glucohydrolase activity" EXACT [GOC:TermGenie] synonym: "up regulation of mucopeptide N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] synonym: "up regulation of muramidase activity" EXACT [GOC:TermGenie] synonym: "up regulation of N,O-diacetylmuramidase activity" EXACT [GOC:TermGenie] synonym: "up regulation of peptidoglycan N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] synonym: "up regulation of PR1-lysozyme" RELATED [GOC:TermGenie] synonym: "up-regulation of 1,4-N-acetylmuramidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of globulin G" RELATED [GOC:TermGenie] synonym: "up-regulation of globulin G1" RELATED [GOC:TermGenie] synonym: "up-regulation of L-7001" RELATED [GOC:TermGenie] synonym: "up-regulation of lysozyme activity" EXACT [GOC:TermGenie] synonym: "up-regulation of lysozyme g" RELATED [GOC:TermGenie] synonym: "up-regulation of mucopeptide glucohydrolase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of mucopeptide N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of muramidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of N,O-diacetylmuramidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of peptidoglycan N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of PR1-lysozyme" RELATED [GOC:TermGenie] synonym: "upregulation of 1,4-N-acetylmuramidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of globulin G" RELATED [GOC:TermGenie] synonym: "upregulation of globulin G1" RELATED [GOC:TermGenie] synonym: "upregulation of L-7001" RELATED [GOC:TermGenie] synonym: "upregulation of lysozyme activity" EXACT [GOC:TermGenie] synonym: "upregulation of lysozyme g" RELATED [GOC:TermGenie] synonym: "upregulation of mucopeptide glucohydrolase activity" EXACT [GOC:TermGenie] synonym: "upregulation of mucopeptide N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] synonym: "upregulation of muramidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of N,O-diacetylmuramidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of peptidoglycan N-acetylmuramoylhydrolase activity" EXACT [GOC:TermGenie] synonym: "upregulation of PR1-lysozyme" RELATED [GOC:TermGenie] is_a: GO:0051345 ! positive regulation of hydrolase activity created_by: mr creation_date: 2014-11-05T21:41:39Z [Term] id: GO:1903609 name: negative regulation of inward rectifier potassium channel activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of inward rectifier potassium channel activity." [GO_REF:0000059, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18923542] subset: gocheck_obsoletion_candidate synonym: "down regulation of inward rectifier potassium channel activity" EXACT [GOC:TermGenie] synonym: "down regulation of Kir channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of inward rectifier potassium channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of Kir channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of inward rectifier potassium channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of Kir channel activity" EXACT [GOC:TermGenie] synonym: "inhibition of inward rectifier potassium channel activity" NARROW [GOC:TermGenie] synonym: "inhibition of Kir channel activity" NARROW [GOC:TermGenie] synonym: "negative regulation of Kir channel activity" EXACT [GOC:TermGenie] is_a: GO:1901979 ! regulation of inward rectifier potassium channel activity is_a: GO:1903817 ! negative regulation of voltage-gated potassium channel activity created_by: rl creation_date: 2014-11-14T20:29:14Z [Term] id: GO:1903611 name: negative regulation of calcium-dependent ATPase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of calcium-dependent ATPase activity." [GO_REF:0000059, GOC:TermGenie, PMID:10861851] subset: gocheck_obsoletion_candidate synonym: "down regulation of calcium-dependent ATPase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of calcium-dependent ATPase activity" EXACT [GOC:TermGenie] synonym: "downregulation of calcium-dependent ATPase activity" EXACT [GOC:TermGenie] synonym: "inhibition of calcium-dependent ATPase activity" NARROW [GOC:TermGenie] is_a: GO:0032780 ! negative regulation of ATP-dependent activity created_by: sl creation_date: 2014-11-18T00:42:57Z [Term] id: GO:1903612 name: positive regulation of calcium-dependent ATPase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of calcium-dependent ATPase activity." [GO_REF:0000059, GOC:TermGenie, PMID:10861851] subset: gocheck_obsoletion_candidate synonym: "activation of calcium-dependent ATPase activity" NARROW [GOC:TermGenie] synonym: "up regulation of calcium-dependent ATPase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of calcium-dependent ATPase activity" EXACT [GOC:TermGenie] synonym: "upregulation of calcium-dependent ATPase activity" EXACT [GOC:TermGenie] is_a: GO:0032781 ! positive regulation of ATP-dependent activity created_by: sl creation_date: 2014-11-18T00:43:06Z [Term] id: GO:1903623 name: negative regulation of RNA polymerase III activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase III activity." [GO_REF:0000059, GOC:TermGenie, PMID:25392932] subset: gocheck_obsoletion_candidate synonym: "down regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter" EXACT [GOC:TermGenie] synonym: "down regulation of RNA polymerase III activity" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA polymerase III activity" EXACT [GOC:TermGenie] synonym: "downregulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter" EXACT [GOC:TermGenie] synonym: "downregulation of RNA polymerase III activity" EXACT [GOC:TermGenie] synonym: "inhibition of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter" NARROW [GOC:TermGenie] synonym: "inhibition of RNA polymerase III activity" NARROW [GOC:TermGenie] synonym: "negative regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter" EXACT [GOC:TermGenie] is_a: GO:0051348 ! negative regulation of transferase activity created_by: al creation_date: 2014-11-19T18:24:37Z [Term] id: GO:1903719 name: regulation of I-kappaB phosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of I-kappaB phosphorylation." [GO_REF:0000058, GOC:TermGenie, PMID:23675531] subset: gocheck_obsoletion_candidate synonym: "regulation of IkappaB phosphorylation" EXACT [GOC:TermGenie] synonym: "regulation of IKB phosphorylation" EXACT [GOC:TermGenie] synonym: "regulation of inhibitor of kappaB phosphorylation" EXACT [GOC:TermGenie] synonym: "regulation of inhibitor of NF-kappaB phosphorylation" EXACT [GOC:TermGenie] is_a: GO:0001932 ! regulation of protein phosphorylation relationship: regulates GO:0007252 ! I-kappaB phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI created_by: lb creation_date: 2014-12-08T15:45:07Z [Term] id: GO:1903720 name: negative regulation of I-kappaB phosphorylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of I-kappaB phosphorylation." [GO_REF:0000058, GOC:TermGenie, PMID:23675531] subset: gocheck_obsoletion_candidate synonym: "inhibition of I-kappaB phosphorylation" NARROW [GOC:TermGenie] synonym: "inhibition of IkappaB phosphorylation" NARROW [GOC:TermGenie] synonym: "inhibition of IKB phosphorylation" NARROW [GOC:TermGenie] synonym: "inhibition of inhibitor of kappaB phosphorylation" NARROW [GOC:TermGenie] synonym: "inhibition of inhibitor of NF-kappaB phosphorylation" NARROW [GOC:TermGenie] synonym: "negative regulation of IkappaB phosphorylation" EXACT [GOC:TermGenie] synonym: "negative regulation of IKB phosphorylation" EXACT [GOC:TermGenie] synonym: "negative regulation of inhibitor of kappaB phosphorylation" EXACT [GOC:TermGenie] synonym: "negative regulation of inhibitor of NF-kappaB phosphorylation" EXACT [GOC:TermGenie] is_a: GO:0001933 ! negative regulation of protein phosphorylation is_a: GO:1903719 ! regulation of I-kappaB phosphorylation relationship: negatively_regulates GO:0007252 ! I-kappaB phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI created_by: lb creation_date: 2014-12-08T15:45:16Z [Term] id: GO:1903721 name: positive regulation of I-kappaB phosphorylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of I-kappaB phosphorylation." [GO_REF:0000058, GOC:TermGenie, PMID:23675531] subset: gocheck_obsoletion_candidate synonym: "activation of I-kappaB phosphorylation" NARROW [GOC:TermGenie] synonym: "activation of IkappaB phosphorylation" NARROW [GOC:TermGenie] synonym: "activation of IKB phosphorylation" NARROW [GOC:TermGenie] synonym: "activation of inhibitor of kappaB phosphorylation" NARROW [GOC:TermGenie] synonym: "activation of inhibitor of NF-kappaB phosphorylation" NARROW [GOC:TermGenie] synonym: "positive regulation of IkappaB phosphorylation" EXACT [GOC:TermGenie] synonym: "positive regulation of IKB phosphorylation" EXACT [GOC:TermGenie] synonym: "positive regulation of inhibitor of kappaB phosphorylation" EXACT [GOC:TermGenie] synonym: "positive regulation of inhibitor of NF-kappaB phosphorylation" EXACT [GOC:TermGenie] synonym: "up regulation of I-kappaB phosphorylation" EXACT [GOC:TermGenie] synonym: "up regulation of IkappaB phosphorylation" EXACT [GOC:TermGenie] synonym: "up regulation of IKB phosphorylation" EXACT [GOC:TermGenie] synonym: "up regulation of inhibitor of kappaB phosphorylation" EXACT [GOC:TermGenie] synonym: "up regulation of inhibitor of NF-kappaB phosphorylation" EXACT [GOC:TermGenie] synonym: "up-regulation of I-kappaB phosphorylation" EXACT [GOC:TermGenie] synonym: "up-regulation of IkappaB phosphorylation" EXACT [GOC:TermGenie] synonym: "up-regulation of IKB phosphorylation" EXACT [GOC:TermGenie] synonym: "up-regulation of inhibitor of kappaB phosphorylation" EXACT [GOC:TermGenie] synonym: "up-regulation of inhibitor of NF-kappaB phosphorylation" EXACT [GOC:TermGenie] synonym: "upregulation of I-kappaB phosphorylation" EXACT [GOC:TermGenie] synonym: "upregulation of IkappaB phosphorylation" EXACT [GOC:TermGenie] synonym: "upregulation of IKB phosphorylation" EXACT [GOC:TermGenie] synonym: "upregulation of inhibitor of kappaB phosphorylation" EXACT [GOC:TermGenie] synonym: "upregulation of inhibitor of NF-kappaB phosphorylation" EXACT [GOC:TermGenie] is_a: GO:0001934 ! positive regulation of protein phosphorylation is_a: GO:1903719 ! regulation of I-kappaB phosphorylation relationship: positively_regulates GO:0007252 ! I-kappaB phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI created_by: lb creation_date: 2014-12-08T15:45:25Z [Term] id: GO:1903755 name: positive regulation of SUMO transferase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of SUMO transferase activity." [GO_REF:0000059, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:19955185] subset: gocheck_obsoletion_candidate synonym: "activation of SMT3 conjugating enzyme" RELATED [GOC:TermGenie] synonym: "activation of SUMO conjugating enzyme activity" RELATED [GOC:TermGenie] synonym: "activation of SUMO transferase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of SMT3 conjugating enzyme" RELATED [GOC:TermGenie] synonym: "positive regulation of SUMO conjugating enzyme activity" RELATED [GOC:TermGenie] synonym: "up regulation of SMT3 conjugating enzyme" RELATED [GOC:TermGenie] synonym: "up regulation of SUMO conjugating enzyme activity" RELATED [GOC:TermGenie] synonym: "up regulation of SUMO transferase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of SMT3 conjugating enzyme" RELATED [GOC:TermGenie] synonym: "up-regulation of SUMO conjugating enzyme activity" RELATED [GOC:TermGenie] synonym: "up-regulation of SUMO transferase activity" EXACT [GOC:TermGenie] synonym: "upregulation of SMT3 conjugating enzyme" RELATED [GOC:TermGenie] synonym: "upregulation of SUMO conjugating enzyme activity" RELATED [GOC:TermGenie] synonym: "upregulation of SUMO transferase activity" EXACT [GOC:TermGenie] is_a: GO:0051347 ! positive regulation of transferase activity created_by: rl creation_date: 2014-12-18T13:05:59Z [Term] id: GO:1903760 name: regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization." [GO_REF:0000059, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18337493] subset: gocheck_obsoletion_candidate synonym: "regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential" NARROW [GOC:TermGenie] synonym: "regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential" EXACT [GOC:TermGenie] is_a: GO:1901016 ! regulation of potassium ion transmembrane transporter activity is_a: GO:2001257 ! regulation of cation channel activity created_by: rl creation_date: 2014-12-19T12:01:59Z [Term] id: GO:1903770 name: negative regulation of beta-galactosidase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of beta-galactosidase activity." [GO_REF:0000059, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:11927518] subset: gocheck_obsoletion_candidate synonym: "down regulation of beta-D-galactanase activity" EXACT [GOC:TermGenie] synonym: "down regulation of beta-D-galactoside galactohydrolase activity" EXACT [GOC:TermGenie] synonym: "down regulation of beta-D-lactosidase activity" EXACT [GOC:TermGenie] synonym: "down regulation of beta-galactosidase activity" EXACT [GOC:TermGenie] synonym: "down regulation of beta-lactosidase activity" EXACT [GOC:TermGenie] synonym: "down regulation of exo-(1->4)-beta-D-galactanase activity" EXACT [GOC:TermGenie] synonym: "down regulation of hydrolact" RELATED [GOC:TermGenie] synonym: "down regulation of lactose hydrolysis" RELATED [GOC:TermGenie] synonym: "down regulation of lactozym" RELATED [GOC:TermGenie] synonym: "down regulation of maxilact" RELATED [GOC:TermGenie] synonym: "down regulation of oryzatym" RELATED [GOC:TermGenie] synonym: "down regulation of S 2107" RELATED [GOC:TermGenie] synonym: "down regulation of sumiklat" RELATED [GOC:TermGenie] synonym: "down regulation of trilactase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of beta-D-galactanase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of beta-D-galactoside galactohydrolase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of beta-D-lactosidase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of beta-galactosidase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of beta-lactosidase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of exo-(1->4)-beta-D-galactanase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of hydrolact" RELATED [GOC:TermGenie] synonym: "down-regulation of lactose hydrolysis" RELATED [GOC:TermGenie] synonym: "down-regulation of lactozym" RELATED [GOC:TermGenie] synonym: "down-regulation of maxilact" RELATED [GOC:TermGenie] synonym: "down-regulation of oryzatym" RELATED [GOC:TermGenie] synonym: "down-regulation of S 2107" RELATED [GOC:TermGenie] synonym: "down-regulation of sumiklat" RELATED [GOC:TermGenie] synonym: "down-regulation of trilactase activity" EXACT [GOC:TermGenie] synonym: "downregulation of beta-D-galactanase activity" EXACT [GOC:TermGenie] synonym: "downregulation of beta-D-galactoside galactohydrolase activity" EXACT [GOC:TermGenie] synonym: "downregulation of beta-D-lactosidase activity" EXACT [GOC:TermGenie] synonym: "downregulation of beta-galactosidase activity" EXACT [GOC:TermGenie] synonym: "downregulation of beta-lactosidase activity" EXACT [GOC:TermGenie] synonym: "downregulation of exo-(1->4)-beta-D-galactanase activity" EXACT [GOC:TermGenie] synonym: "downregulation of hydrolact" RELATED [GOC:TermGenie] synonym: "downregulation of lactose hydrolysis" RELATED [GOC:TermGenie] synonym: "downregulation of lactozym" RELATED [GOC:TermGenie] synonym: "downregulation of maxilact" RELATED [GOC:TermGenie] synonym: "downregulation of oryzatym" RELATED [GOC:TermGenie] synonym: "downregulation of S 2107" RELATED [GOC:TermGenie] synonym: "downregulation of sumiklat" RELATED [GOC:TermGenie] synonym: "downregulation of trilactase activity" EXACT [GOC:TermGenie] synonym: "inhibition of beta-D-galactanase activity" NARROW [GOC:TermGenie] synonym: "inhibition of beta-D-galactoside galactohydrolase activity" NARROW [GOC:TermGenie] synonym: "inhibition of beta-D-lactosidase activity" NARROW [GOC:TermGenie] synonym: "inhibition of beta-galactosidase activity" NARROW [GOC:TermGenie] synonym: "inhibition of beta-lactosidase activity" NARROW [GOC:TermGenie] synonym: "inhibition of exo-(1->4)-beta-D-galactanase activity" NARROW [GOC:TermGenie] synonym: "inhibition of hydrolact" RELATED [GOC:TermGenie] synonym: "inhibition of lactose hydrolysis" RELATED [GOC:TermGenie] synonym: "inhibition of lactozym" RELATED [GOC:TermGenie] synonym: "inhibition of maxilact" RELATED [GOC:TermGenie] synonym: "inhibition of oryzatym" RELATED [GOC:TermGenie] synonym: "inhibition of S 2107" RELATED [GOC:TermGenie] synonym: "inhibition of sumiklat" RELATED [GOC:TermGenie] synonym: "inhibition of trilactase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of beta-D-galactanase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of beta-D-galactoside galactohydrolase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of beta-D-lactosidase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of beta-lactosidase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of exo-(1->4)-beta-D-galactanase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of hydrolact" RELATED [GOC:TermGenie] synonym: "negative regulation of lactose hydrolysis" RELATED [GOC:TermGenie] synonym: "negative regulation of lactozym" RELATED [GOC:TermGenie] synonym: "negative regulation of maxilact" RELATED [GOC:TermGenie] synonym: "negative regulation of oryzatym" RELATED [GOC:TermGenie] synonym: "negative regulation of S 2107" RELATED [GOC:TermGenie] synonym: "negative regulation of sumiklat" RELATED [GOC:TermGenie] synonym: "negative regulation of trilactase activity" EXACT [GOC:TermGenie] is_a: GO:0051346 ! negative regulation of hydrolase activity created_by: nc creation_date: 2015-01-06T10:53:22Z [Term] id: GO:1903771 name: positive regulation of beta-galactosidase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of beta-galactosidase activity." [GO_REF:0000059, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:11927518] subset: gocheck_obsoletion_candidate synonym: "activation of beta-D-galactanase activity" NARROW [GOC:TermGenie] synonym: "activation of beta-D-galactoside galactohydrolase activity" NARROW [GOC:TermGenie] synonym: "activation of beta-D-lactosidase activity" NARROW [GOC:TermGenie] synonym: "activation of beta-galactosidase activity" NARROW [GOC:TermGenie] synonym: "activation of beta-lactosidase activity" NARROW [GOC:TermGenie] synonym: "activation of exo-(1->4)-beta-D-galactanase activity" NARROW [GOC:TermGenie] synonym: "activation of hydrolact" RELATED [GOC:TermGenie] synonym: "activation of lactose hydrolysis" RELATED [GOC:TermGenie] synonym: "activation of lactozym" RELATED [GOC:TermGenie] synonym: "activation of maxilact" RELATED [GOC:TermGenie] synonym: "activation of oryzatym" RELATED [GOC:TermGenie] synonym: "activation of S 2107" RELATED [GOC:TermGenie] synonym: "activation of sumiklat" RELATED [GOC:TermGenie] synonym: "activation of trilactase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of beta-D-galactanase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of beta-D-galactoside galactohydrolase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of beta-D-lactosidase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of beta-lactosidase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of exo-(1->4)-beta-D-galactanase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of hydrolact" RELATED [GOC:TermGenie] synonym: "positive regulation of lactose hydrolysis" RELATED [GOC:TermGenie] synonym: "positive regulation of lactozym" RELATED [GOC:TermGenie] synonym: "positive regulation of maxilact" RELATED [GOC:TermGenie] synonym: "positive regulation of oryzatym" RELATED [GOC:TermGenie] synonym: "positive regulation of S 2107" RELATED [GOC:TermGenie] synonym: "positive regulation of sumiklat" RELATED [GOC:TermGenie] synonym: "positive regulation of trilactase activity" EXACT [GOC:TermGenie] synonym: "up regulation of beta-D-galactanase activity" EXACT [GOC:TermGenie] synonym: "up regulation of beta-D-galactoside galactohydrolase activity" EXACT [GOC:TermGenie] synonym: "up regulation of beta-D-lactosidase activity" EXACT [GOC:TermGenie] synonym: "up regulation of beta-galactosidase activity" EXACT [GOC:TermGenie] synonym: "up regulation of beta-lactosidase activity" EXACT [GOC:TermGenie] synonym: "up regulation of exo-(1->4)-beta-D-galactanase activity" EXACT [GOC:TermGenie] synonym: "up regulation of hydrolact" RELATED [GOC:TermGenie] synonym: "up regulation of lactose hydrolysis" RELATED [GOC:TermGenie] synonym: "up regulation of lactozym" RELATED [GOC:TermGenie] synonym: "up regulation of maxilact" RELATED [GOC:TermGenie] synonym: "up regulation of oryzatym" RELATED [GOC:TermGenie] synonym: "up regulation of S 2107" RELATED [GOC:TermGenie] synonym: "up regulation of sumiklat" RELATED [GOC:TermGenie] synonym: "up regulation of trilactase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of beta-D-galactanase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of beta-D-galactoside galactohydrolase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of beta-D-lactosidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of beta-galactosidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of beta-lactosidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of exo-(1->4)-beta-D-galactanase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of hydrolact" RELATED [GOC:TermGenie] synonym: "up-regulation of lactose hydrolysis" RELATED [GOC:TermGenie] synonym: "up-regulation of lactozym" RELATED [GOC:TermGenie] synonym: "up-regulation of maxilact" RELATED [GOC:TermGenie] synonym: "up-regulation of oryzatym" RELATED [GOC:TermGenie] synonym: "up-regulation of S 2107" RELATED [GOC:TermGenie] synonym: "up-regulation of sumiklat" RELATED [GOC:TermGenie] synonym: "up-regulation of trilactase activity" EXACT [GOC:TermGenie] synonym: "upregulation of beta-D-galactanase activity" EXACT [GOC:TermGenie] synonym: "upregulation of beta-D-galactoside galactohydrolase activity" EXACT [GOC:TermGenie] synonym: "upregulation of beta-D-lactosidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of beta-galactosidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of beta-lactosidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of exo-(1->4)-beta-D-galactanase activity" EXACT [GOC:TermGenie] synonym: "upregulation of hydrolact" RELATED [GOC:TermGenie] synonym: "upregulation of lactose hydrolysis" RELATED [GOC:TermGenie] synonym: "upregulation of lactozym" RELATED [GOC:TermGenie] synonym: "upregulation of maxilact" RELATED [GOC:TermGenie] synonym: "upregulation of oryzatym" RELATED [GOC:TermGenie] synonym: "upregulation of S 2107" RELATED [GOC:TermGenie] synonym: "upregulation of sumiklat" RELATED [GOC:TermGenie] synonym: "upregulation of trilactase activity" EXACT [GOC:TermGenie] is_a: GO:0051345 ! positive regulation of hydrolase activity created_by: nc creation_date: 2015-01-06T10:53:32Z [Term] id: GO:1903817 name: negative regulation of voltage-gated potassium channel activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity." [GO_REF:0000059, GOC:TermGenie, PMID:19219384] subset: gocheck_obsoletion_candidate synonym: "down regulation of voltage gated potassium channel activity" EXACT [GOC:TermGenie] synonym: "down regulation of voltage-dependent potassium channel activity" EXACT [GOC:TermGenie] synonym: "down regulation of voltage-gated potassium channel activity" EXACT [GOC:TermGenie] synonym: "down regulation of voltage-gated potassium ion channel activity" EXACT [GOC:TermGenie] synonym: "down regulation of voltage-sensitive potassium channel" EXACT [GOC:TermGenie] synonym: "down-regulation of voltage gated potassium channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of voltage-dependent potassium channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of voltage-gated potassium channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of voltage-gated potassium ion channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of voltage-sensitive potassium channel" EXACT [GOC:TermGenie] synonym: "downregulation of voltage gated potassium channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of voltage-dependent potassium channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of voltage-gated potassium channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of voltage-gated potassium ion channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of voltage-sensitive potassium channel" EXACT [GOC:TermGenie] synonym: "inhibition of voltage gated potassium channel activity" NARROW [GOC:TermGenie] synonym: "inhibition of voltage-dependent potassium channel activity" NARROW [GOC:TermGenie] synonym: "inhibition of voltage-gated potassium channel activity" NARROW [GOC:TermGenie] synonym: "inhibition of voltage-gated potassium ion channel activity" NARROW [GOC:TermGenie] synonym: "inhibition of voltage-sensitive potassium channel" NARROW [GOC:TermGenie] synonym: "negative regulation of voltage gated potassium channel activity" EXACT [GOC:TermGenie] synonym: "negative regulation of voltage-dependent potassium channel activity" EXACT [GOC:TermGenie] synonym: "negative regulation of voltage-gated potassium ion channel activity" EXACT [GOC:TermGenie] synonym: "negative regulation of voltage-sensitive potassium channel" EXACT [GOC:TermGenie] is_a: GO:1901017 ! negative regulation of potassium ion transmembrane transporter activity is_a: GO:2001258 ! negative regulation of cation channel activity created_by: sl creation_date: 2015-01-16T17:22:08Z [Term] id: GO:1903818 name: positive regulation of voltage-gated potassium channel activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity." [GO_REF:0000059, GOC:TermGenie, PMID:19219384] subset: gocheck_obsoletion_candidate synonym: "activation of voltage gated potassium channel activity" NARROW [GOC:TermGenie] synonym: "activation of voltage-dependent potassium channel activity" NARROW [GOC:TermGenie] synonym: "activation of voltage-gated potassium channel activity" NARROW [GOC:TermGenie] synonym: "activation of voltage-gated potassium ion channel activity" NARROW [GOC:TermGenie] synonym: "activation of voltage-sensitive potassium channel" NARROW [GOC:TermGenie] synonym: "positive regulation of voltage gated potassium channel activity" EXACT [GOC:TermGenie] synonym: "positive regulation of voltage-dependent potassium channel activity" EXACT [GOC:TermGenie] synonym: "positive regulation of voltage-gated potassium ion channel activity" EXACT [GOC:TermGenie] synonym: "positive regulation of voltage-sensitive potassium channel" EXACT [GOC:TermGenie] synonym: "up regulation of voltage gated potassium channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of voltage-dependent potassium channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of voltage-gated potassium channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of voltage-gated potassium ion channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of voltage-sensitive potassium channel" EXACT [GOC:TermGenie] synonym: "up-regulation of voltage gated potassium channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of voltage-dependent potassium channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of voltage-gated potassium channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of voltage-gated potassium ion channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of voltage-sensitive potassium channel" EXACT [GOC:TermGenie] synonym: "upregulation of voltage gated potassium channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of voltage-dependent potassium channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of voltage-gated potassium channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of voltage-gated potassium ion channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of voltage-sensitive potassium channel" EXACT [GOC:TermGenie] is_a: GO:1901018 ! positive regulation of potassium ion transmembrane transporter activity is_a: GO:2001259 ! positive regulation of cation channel activity created_by: sl creation_date: 2015-01-16T17:22:18Z [Term] id: GO:1903912 name: negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum stress-induced eiF2alpha phosphorylation." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:16835242] subset: gocheck_obsoletion_candidate synonym: "down regulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] synonym: "down regulation of eiF2alpha phosphorylation in response to ER stress" EXACT [GOC:TermGenie] synonym: "down regulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] synonym: "down-regulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] synonym: "down-regulation of eiF2alpha phosphorylation in response to ER stress" EXACT [GOC:TermGenie] synonym: "down-regulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] synonym: "downregulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] synonym: "downregulation of eiF2alpha phosphorylation in response to ER stress" EXACT [GOC:TermGenie] synonym: "downregulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] synonym: "inhibition of eiF2alpha phosphorylation in response to endoplasmic reticulum stress" NARROW [GOC:TermGenie] synonym: "inhibition of eiF2alpha phosphorylation in response to ER stress" NARROW [GOC:TermGenie] synonym: "inhibition of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress" NARROW [GOC:TermGenie] synonym: "negative regulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress" EXACT [] synonym: "negative regulation of eiF2alpha phosphorylation in response to ER stress" EXACT [GOC:TermGenie] synonym: "negative regulation of ER stress-induced eIF2 alpha phosphorylation" EXACT [GOC:bf] synonym: "negative regulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress" EXACT [GOC:TermGenie] is_a: GO:0001933 ! negative regulation of protein phosphorylation relationship: negatively_regulates GO:0036492 ! eiF2alpha phosphorylation in response to endoplasmic reticulum stress property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI created_by: bf creation_date: 2015-02-09T10:58:55Z [Term] id: GO:1903934 name: positive regulation of DNA primase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of DNA primase activity." [GO_REF:0000059, GOC:TermGenie, PMID:14766746] subset: gocheck_obsoletion_candidate synonym: "activation of DNA primase activity" NARROW [GOC:TermGenie] synonym: "up regulation of DNA primase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA primase activity" EXACT [GOC:TermGenie] synonym: "upregulation of DNA primase activity" EXACT [GOC:TermGenie] is_a: GO:0051347 ! positive regulation of transferase activity created_by: mah creation_date: 2015-02-12T14:28:45Z [Term] id: GO:1903996 name: negative regulation of non-membrane spanning protein tyrosine kinase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity." [GO_REF:0000059, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:10518561] subset: gocheck_obsoletion_candidate synonym: "down regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity" EXACT [GOC:TermGenie] synonym: "down regulation of Bruton's tyrosine kinase activity" NARROW [GOC:TermGenie] synonym: "down regulation of cytoplasmic protein tyrosine kinase activity" NARROW [GOC:TermGenie] synonym: "down regulation of focal adhesion kinase activity" NARROW [GOC:TermGenie] synonym: "down regulation of janus kinase 1 activity" NARROW [GOC:TermGenie] synonym: "down regulation of janus kinase 2 activity" NARROW [GOC:TermGenie] synonym: "down regulation of janus kinase 3 activity" NARROW [GOC:TermGenie] synonym: "down regulation of non-membrane spanning protein tyrosine kinase activity" EXACT [GOC:TermGenie] synonym: "down regulation of non-specific protein-tyrosine kinase activity" EXACT [GOC:TermGenie] synonym: "down regulation of p60c-src protein tyrosine kinase activity" NARROW [GOC:TermGenie] synonym: "down-regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity" EXACT [GOC:TermGenie] synonym: "down-regulation of Bruton's tyrosine kinase activity" NARROW [GOC:TermGenie] synonym: "down-regulation of cytoplasmic protein tyrosine kinase activity" NARROW [GOC:TermGenie] synonym: "down-regulation of focal adhesion kinase activity" NARROW [GOC:TermGenie] synonym: "down-regulation of janus kinase 1 activity" NARROW [GOC:TermGenie] synonym: "down-regulation of janus kinase 2 activity" NARROW [GOC:TermGenie] synonym: "down-regulation of janus kinase 3 activity" NARROW [GOC:TermGenie] synonym: "down-regulation of non-membrane spanning protein tyrosine kinase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of non-specific protein-tyrosine kinase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of p60c-src protein tyrosine kinase activity" NARROW [GOC:TermGenie] synonym: "downregulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity" EXACT [GOC:TermGenie] synonym: "downregulation of Bruton's tyrosine kinase activity" NARROW [GOC:TermGenie] synonym: "downregulation of cytoplasmic protein tyrosine kinase activity" NARROW [GOC:TermGenie] synonym: "downregulation of focal adhesion kinase activity" NARROW [GOC:TermGenie] synonym: "downregulation of janus kinase 1 activity" NARROW [GOC:TermGenie] synonym: "downregulation of janus kinase 2 activity" NARROW [GOC:TermGenie] synonym: "downregulation of janus kinase 3 activity" NARROW [GOC:TermGenie] synonym: "downregulation of non-membrane spanning protein tyrosine kinase activity" EXACT [GOC:TermGenie] synonym: "downregulation of non-specific protein-tyrosine kinase activity" EXACT [GOC:TermGenie] synonym: "downregulation of p60c-src protein tyrosine kinase activity" NARROW [GOC:TermGenie] synonym: "inhibition of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity" NARROW [GOC:TermGenie] synonym: "inhibition of Bruton's tyrosine kinase activity" NARROW [GOC:TermGenie] synonym: "inhibition of cytoplasmic protein tyrosine kinase activity" NARROW [GOC:TermGenie] synonym: "inhibition of focal adhesion kinase activity" NARROW [GOC:TermGenie] synonym: "inhibition of janus kinase 1 activity" NARROW [GOC:TermGenie] synonym: "inhibition of janus kinase 2 activity" NARROW [GOC:TermGenie] synonym: "inhibition of janus kinase 3 activity" NARROW [GOC:TermGenie] synonym: "inhibition of non-membrane spanning protein tyrosine kinase activity" NARROW [GOC:TermGenie] synonym: "inhibition of non-specific protein-tyrosine kinase activity" NARROW [GOC:TermGenie] synonym: "inhibition of p60c-src protein tyrosine kinase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity" EXACT [GOC:TermGenie] synonym: "negative regulation of Bruton's tyrosine kinase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of cytoplasmic protein tyrosine kinase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of focal adhesion kinase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of janus kinase 1 activity" NARROW [GOC:TermGenie] synonym: "negative regulation of janus kinase 2 activity" NARROW [GOC:TermGenie] synonym: "negative regulation of janus kinase 3 activity" NARROW [GOC:TermGenie] synonym: "negative regulation of non-specific protein-tyrosine kinase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of p60c-src protein tyrosine kinase activity" NARROW [GOC:TermGenie] is_a: GO:0061099 ! negative regulation of protein tyrosine kinase activity created_by: nc creation_date: 2015-03-05T16:34:41Z [Term] id: GO:1904030 name: negative regulation of cyclin-dependent protein kinase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cyclin-dependent protein kinase activity." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:22995177] subset: gocheck_obsoletion_candidate synonym: "down regulation of cyclin-dependent protein kinase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of cyclin-dependent protein kinase activity" EXACT [GOC:TermGenie] synonym: "downregulation of cyclin-dependent protein kinase activity" EXACT [GOC:TermGenie] synonym: "inhibition of cyclin-dependent protein kinase activity" EXACT [GOC:TermGenie] is_a: GO:0006469 ! negative regulation of protein kinase activity created_by: als creation_date: 2015-03-13T15:43:44Z [Term] id: GO:1904031 name: positive regulation of cyclin-dependent protein kinase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein kinase activity." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:22995177] subset: gocheck_obsoletion_candidate synonym: "activation of cyclin-dependent protein kinase activity" NARROW [GOC:TermGenie] synonym: "up regulation of cyclin-dependent protein kinase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of cyclin-dependent protein kinase activity" EXACT [GOC:TermGenie] synonym: "upregulation of cyclin-dependent protein kinase activity" EXACT [GOC:TermGenie] is_a: GO:0045860 ! positive regulation of protein kinase activity created_by: als creation_date: 2015-03-13T15:43:50Z [Term] id: GO:1904042 name: negative regulation of cystathionine beta-synthase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cystathionine beta-synthase activity." [GO_REF:0000059, GOC:BHF, GOC:hal, GOC:TermGenie, PMID:24416422] subset: gocheck_obsoletion_candidate synonym: "down regulation of beta-thionase activity" EXACT [GOC:TermGenie] synonym: "down regulation of cystathionine beta-synthase activity" EXACT [GOC:TermGenie] synonym: "down regulation of L-serine hydro-lyase (adding homocysteine)" EXACT [GOC:TermGenie] synonym: "down regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)" EXACT [GOC:TermGenie] synonym: "down regulation of methylcysteine synthase activity" EXACT [GOC:TermGenie] synonym: "down regulation of serine sulfhydrase activity" EXACT [GOC:TermGenie] synonym: "down regulation of serine sulfhydrylase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of beta-thionase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of cystathionine beta-synthase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of L-serine hydro-lyase (adding homocysteine)" EXACT [GOC:TermGenie] synonym: "down-regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)" EXACT [GOC:TermGenie] synonym: "down-regulation of methylcysteine synthase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of serine sulfhydrase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of serine sulfhydrylase activity" EXACT [GOC:TermGenie] synonym: "downregulation of beta-thionase activity" EXACT [GOC:TermGenie] synonym: "downregulation of cystathionine beta-synthase activity" EXACT [GOC:TermGenie] synonym: "downregulation of L-serine hydro-lyase (adding homocysteine)" EXACT [GOC:TermGenie] synonym: "downregulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)" EXACT [GOC:TermGenie] synonym: "downregulation of methylcysteine synthase activity" EXACT [GOC:TermGenie] synonym: "downregulation of serine sulfhydrase activity" EXACT [GOC:TermGenie] synonym: "downregulation of serine sulfhydrylase activity" EXACT [GOC:TermGenie] synonym: "inhibition of beta-thionase activity" NARROW [GOC:TermGenie] synonym: "inhibition of cystathionine beta-synthase activity" NARROW [GOC:TermGenie] synonym: "inhibition of L-serine hydro-lyase (adding homocysteine)" NARROW [GOC:TermGenie] synonym: "inhibition of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)" NARROW [GOC:TermGenie] synonym: "inhibition of methylcysteine synthase activity" NARROW [GOC:TermGenie] synonym: "inhibition of serine sulfhydrase activity" NARROW [GOC:TermGenie] synonym: "inhibition of serine sulfhydrylase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of beta-thionase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of L-serine hydro-lyase (adding homocysteine)" EXACT [GOC:TermGenie] synonym: "negative regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)" EXACT [GOC:TermGenie] synonym: "negative regulation of methylcysteine synthase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of serine sulfhydrase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of serine sulfhydrylase activity" EXACT [GOC:TermGenie] is_a: GO:0051350 ! negative regulation of lyase activity created_by: hal creation_date: 2015-03-16T15:52:47Z [Term] id: GO:1904098 name: regulation of protein O-linked glycosylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein O-linked glycosylation." [GO_REF:0000058, GOC:TermGenie, PMID:24509081] subset: gocheck_obsoletion_candidate synonym: "regulation of protein amino acid O-linked glycosylation" EXACT [GOC:TermGenie] relationship: regulates GO:0043412 ! macromolecule modification created_by: krc creation_date: 2015-03-27T16:09:58Z [Term] id: GO:1904099 name: negative regulation of protein O-linked glycosylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein O-linked glycosylation." [GO_REF:0000058, GOC:TermGenie, PMID:24509081] subset: gocheck_obsoletion_candidate synonym: "down regulation of protein amino acid O-linked glycosylation" EXACT [GOC:TermGenie] synonym: "down regulation of protein O-linked glycosylation" EXACT [GOC:TermGenie] synonym: "down-regulation of protein amino acid O-linked glycosylation" EXACT [GOC:TermGenie] synonym: "down-regulation of protein O-linked glycosylation" EXACT [GOC:TermGenie] synonym: "downregulation of protein amino acid O-linked glycosylation" EXACT [GOC:TermGenie] synonym: "downregulation of protein O-linked glycosylation" EXACT [GOC:TermGenie] synonym: "inhibition of protein amino acid O-linked glycosylation" NARROW [GOC:TermGenie] synonym: "inhibition of protein O-linked glycosylation" NARROW [GOC:TermGenie] synonym: "negative regulation of protein amino acid O-linked glycosylation" EXACT [GOC:TermGenie] is_a: GO:0031400 ! negative regulation of protein modification process is_a: GO:1904098 ! regulation of protein O-linked glycosylation created_by: krc creation_date: 2015-03-27T16:10:04Z [Term] id: GO:1904100 name: positive regulation of protein O-linked glycosylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein O-linked glycosylation." [GO_REF:0000058, GOC:TermGenie, PMID:24509081] subset: gocheck_obsoletion_candidate synonym: "activation of protein amino acid O-linked glycosylation" NARROW [GOC:TermGenie] synonym: "activation of protein O-linked glycosylation" NARROW [GOC:TermGenie] synonym: "positive regulation of protein amino acid O-linked glycosylation" EXACT [GOC:TermGenie] synonym: "up regulation of protein amino acid O-linked glycosylation" EXACT [GOC:TermGenie] synonym: "up regulation of protein O-linked glycosylation" EXACT [GOC:TermGenie] synonym: "up-regulation of protein amino acid O-linked glycosylation" EXACT [GOC:TermGenie] synonym: "up-regulation of protein O-linked glycosylation" EXACT [GOC:TermGenie] synonym: "upregulation of protein amino acid O-linked glycosylation" EXACT [GOC:TermGenie] synonym: "upregulation of protein O-linked glycosylation" EXACT [GOC:TermGenie] is_a: GO:0031401 ! positive regulation of protein modification process is_a: GO:1904098 ! regulation of protein O-linked glycosylation created_by: krc creation_date: 2015-03-27T16:10:10Z [Term] id: GO:1904182 name: regulation of pyruvate dehydrogenase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of pyruvate dehydrogenase activity." [GO_REF:0000059, GOC:dph, GOC:TermGenie, PMID:25525879] subset: gocheck_obsoletion_candidate synonym: "regulation of pyruvic acid dehydrogenase activity" EXACT [GOC:TermGenie] synonym: "regulation of pyruvic dehydrogenase activity" EXACT [GOC:TermGenie] is_a: GO:0051341 ! regulation of oxidoreductase activity created_by: dph creation_date: 2015-05-05T14:17:27Z [Term] id: GO:1904220 name: regulation of serine C-palmitoyltransferase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of serine C-palmitoyltransferase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16120614] comment: Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of the substrate availability subset: gocheck_obsoletion_candidate synonym: "regulation of 3-oxosphinganine synthetase activity" EXACT [GOC:TermGenie] synonym: "regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] synonym: "regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" EXACT [GOC:TermGenie] synonym: "regulation of serine palmitoyltransferase" BROAD [GOC:TermGenie] synonym: "regulation of SPT" RELATED [GOC:TermGenie] is_a: GO:0051338 ! regulation of transferase activity created_by: rl creation_date: 2015-05-15T08:27:33Z [Term] id: GO:1904221 name: negative regulation of serine C-palmitoyltransferase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of serine C-palmitoyltransferase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16120614] comment: Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of the substrate availability subset: gocheck_obsoletion_candidate synonym: "down regulation of 3-oxosphinganine synthetase activity" EXACT [GOC:TermGenie] synonym: "down regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] synonym: "down regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" EXACT [GOC:TermGenie] synonym: "down regulation of serine C-palmitoyltransferase activity" EXACT [GOC:TermGenie] synonym: "down regulation of SPT" RELATED [GOC:TermGenie] synonym: "down-regulation of 3-oxosphinganine synthetase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] synonym: "down-regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" EXACT [GOC:TermGenie] synonym: "down-regulation of serine C-palmitoyltransferase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of SPT" RELATED [GOC:TermGenie] synonym: "downregulation of 3-oxosphinganine synthetase activity" EXACT [GOC:TermGenie] synonym: "downregulation of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] synonym: "downregulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" EXACT [GOC:TermGenie] synonym: "downregulation of serine C-palmitoyltransferase activity" EXACT [GOC:TermGenie] synonym: "downregulation of SPT" RELATED [GOC:TermGenie] synonym: "inhibition of 3-oxosphinganine synthetase activity" NARROW [GOC:TermGenie] synonym: "inhibition of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] synonym: "inhibition of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" NARROW [GOC:TermGenie] synonym: "inhibition of serine C-palmitoyltransferase activity" NARROW [GOC:TermGenie] synonym: "inhibition of SPT" RELATED [GOC:TermGenie] synonym: "negative regulation of 3-oxosphinganine synthetase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] synonym: "negative regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" EXACT [GOC:TermGenie] synonym: "negative regulation of SPT" RELATED [GOC:TermGenie] is_a: GO:0051348 ! negative regulation of transferase activity is_a: GO:1904220 ! regulation of serine C-palmitoyltransferase activity created_by: rl creation_date: 2015-05-15T08:27:39Z [Term] id: GO:1904222 name: positive regulation of serine C-palmitoyltransferase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of serine C-palmitoyltransferase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16120614] comment: Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of the substrate availability subset: gocheck_obsoletion_candidate synonym: "activation of 3-oxosphinganine synthetase activity" NARROW [GOC:TermGenie] synonym: "activation of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] synonym: "activation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" NARROW [GOC:TermGenie] synonym: "activation of serine C-palmitoyltransferase activity" NARROW [GOC:TermGenie] synonym: "activation of SPT" RELATED [GOC:TermGenie] synonym: "positive regulation of 3-oxosphinganine synthetase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] synonym: "positive regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" EXACT [GOC:TermGenie] synonym: "positive regulation of SPT" RELATED [GOC:TermGenie] synonym: "up regulation of 3-oxosphinganine synthetase activity" EXACT [GOC:TermGenie] synonym: "up regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] synonym: "up regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" EXACT [GOC:TermGenie] synonym: "up regulation of serine C-palmitoyltransferase activity" EXACT [GOC:TermGenie] synonym: "up regulation of SPT" RELATED [GOC:TermGenie] synonym: "up-regulation of 3-oxosphinganine synthetase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] synonym: "up-regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" EXACT [GOC:TermGenie] synonym: "up-regulation of serine C-palmitoyltransferase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of SPT" RELATED [GOC:TermGenie] synonym: "upregulation of 3-oxosphinganine synthetase activity" EXACT [GOC:TermGenie] synonym: "upregulation of acyl-CoA:serine C-2 acyltransferase decarboxylating" RELATED [GOC:TermGenie] synonym: "upregulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity" EXACT [GOC:TermGenie] synonym: "upregulation of serine C-palmitoyltransferase activity" EXACT [GOC:TermGenie] synonym: "upregulation of SPT" RELATED [GOC:TermGenie] is_a: GO:0051347 ! positive regulation of transferase activity is_a: GO:1904220 ! regulation of serine C-palmitoyltransferase activity created_by: rl creation_date: 2015-05-15T08:27:45Z [Term] id: GO:1904227 name: negative regulation of glycogen synthase activity, transferring glucose-1-phosphate namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17569761] subset: gocheck_obsoletion_candidate synonym: "down regulation of glycogen synthase activity, transferring glucose-1-phosphate" EXACT [GOC:TermGenie] synonym: "down-regulation of glycogen synthase activity, transferring glucose-1-phosphate" EXACT [GOC:TermGenie] synonym: "downregulation of glycogen synthase activity, transferring glucose-1-phosphate" EXACT [GOC:TermGenie] synonym: "inhibition of glycogen synthase activity, transferring glucose-1-phosphate" NARROW [GOC:TermGenie] is_a: GO:0051348 ! negative regulation of transferase activity created_by: rl creation_date: 2015-05-15T09:23:14Z [Term] id: GO:1904229 name: regulation of succinate dehydrogenase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of succinate dehydrogenase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18160053] subset: gocheck_obsoletion_candidate synonym: "regulation of fumarate dehydrogenase activity" EXACT [GOC:TermGenie] synonym: "regulation of fumarate reductase activity" EXACT [GOC:TermGenie] synonym: "regulation of fumaric hydrogenase activity" EXACT [GOC:TermGenie] synonym: "regulation of succinate oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "regulation of succinate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "regulation of succinate:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "regulation of succinic acid dehydrogenase activity" EXACT [GOC:TermGenie] synonym: "regulation of succinic dehydrogenase activity" BROAD [GOC:TermGenie] synonym: "regulation of succinodehydrogenase activity" EXACT [GOC:TermGenie] synonym: "regulation of succinyl dehydrogenase activity" EXACT [GOC:TermGenie] is_a: GO:0051341 ! regulation of oxidoreductase activity created_by: rl creation_date: 2015-05-15T09:51:08Z [Term] id: GO:1904231 name: positive regulation of succinate dehydrogenase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of succinate dehydrogenase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18160053] subset: gocheck_obsoletion_candidate synonym: "activation of fumarate dehydrogenase activity" NARROW [GOC:TermGenie] synonym: "activation of fumarate reductase activity" NARROW [GOC:TermGenie] synonym: "activation of fumaric hydrogenase activity" NARROW [GOC:TermGenie] synonym: "activation of succinate dehydrogenase activity" NARROW [GOC:TermGenie] synonym: "activation of succinate oxidoreductase activity" NARROW [GOC:TermGenie] synonym: "activation of succinate:(acceptor) oxidoreductase activity" NARROW [GOC:TermGenie] synonym: "activation of succinate:acceptor oxidoreductase activity" NARROW [GOC:TermGenie] synonym: "activation of succinic acid dehydrogenase activity" NARROW [GOC:TermGenie] synonym: "activation of succinodehydrogenase activity" NARROW [GOC:TermGenie] synonym: "activation of succinyl dehydrogenase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of fumarate dehydrogenase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of fumarate reductase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of fumaric hydrogenase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of succinate oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of succinate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of succinate:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of succinic acid dehydrogenase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of succinodehydrogenase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of succinyl dehydrogenase activity" EXACT [GOC:TermGenie] synonym: "up regulation of fumarate dehydrogenase activity" EXACT [GOC:TermGenie] synonym: "up regulation of fumarate reductase activity" EXACT [GOC:TermGenie] synonym: "up regulation of fumaric hydrogenase activity" EXACT [GOC:TermGenie] synonym: "up regulation of succinate dehydrogenase activity" EXACT [GOC:TermGenie] synonym: "up regulation of succinate oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "up regulation of succinate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "up regulation of succinate:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "up regulation of succinic acid dehydrogenase activity" EXACT [GOC:TermGenie] synonym: "up regulation of succinodehydrogenase activity" EXACT [GOC:TermGenie] synonym: "up regulation of succinyl dehydrogenase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of fumarate dehydrogenase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of fumarate reductase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of fumaric hydrogenase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of succinate dehydrogenase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of succinate oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of succinate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of succinate:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of succinic acid dehydrogenase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of succinodehydrogenase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of succinyl dehydrogenase activity" EXACT [GOC:TermGenie] synonym: "upregulation of fumarate dehydrogenase activity" EXACT [GOC:TermGenie] synonym: "upregulation of fumarate reductase activity" EXACT [GOC:TermGenie] synonym: "upregulation of fumaric hydrogenase activity" EXACT [GOC:TermGenie] synonym: "upregulation of succinate dehydrogenase activity" EXACT [GOC:TermGenie] synonym: "upregulation of succinate oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "upregulation of succinate:(acceptor) oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "upregulation of succinate:acceptor oxidoreductase activity" EXACT [GOC:TermGenie] synonym: "upregulation of succinic acid dehydrogenase activity" EXACT [GOC:TermGenie] synonym: "upregulation of succinodehydrogenase activity" EXACT [GOC:TermGenie] synonym: "upregulation of succinyl dehydrogenase activity" EXACT [GOC:TermGenie] is_a: GO:0051353 ! positive regulation of oxidoreductase activity is_a: GO:1904229 ! regulation of succinate dehydrogenase activity created_by: rl creation_date: 2015-05-15T09:51:20Z [Term] id: GO:1904233 name: negative regulation of aconitate hydratase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of aconitate hydratase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18160053] subset: gocheck_obsoletion_candidate synonym: "down regulation of aconitase activity" EXACT [GOC:TermGenie] synonym: "down regulation of aconitate hydratase activity" EXACT [GOC:TermGenie] synonym: "down regulation of cis-aconitase activity" EXACT [GOC:TermGenie] synonym: "down regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" EXACT [GOC:TermGenie] synonym: "down regulation of citrate(isocitrate) hydro-lyase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of aconitase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of aconitate hydratase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of cis-aconitase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" EXACT [GOC:TermGenie] synonym: "down-regulation of citrate(isocitrate) hydro-lyase activity" EXACT [GOC:TermGenie] synonym: "downregulation of aconitase activity" EXACT [GOC:TermGenie] synonym: "downregulation of aconitate hydratase activity" EXACT [GOC:TermGenie] synonym: "downregulation of cis-aconitase activity" EXACT [GOC:TermGenie] synonym: "downregulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" EXACT [GOC:TermGenie] synonym: "downregulation of citrate(isocitrate) hydro-lyase activity" EXACT [GOC:TermGenie] synonym: "inhibition of aconitase activity" NARROW [GOC:TermGenie] synonym: "inhibition of aconitate hydratase activity" NARROW [GOC:TermGenie] synonym: "inhibition of cis-aconitase activity" NARROW [GOC:TermGenie] synonym: "inhibition of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" NARROW [GOC:TermGenie] synonym: "inhibition of citrate(isocitrate) hydro-lyase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of aconitase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of cis-aconitase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" EXACT [GOC:TermGenie] synonym: "negative regulation of citrate(isocitrate) hydro-lyase activity" EXACT [GOC:TermGenie] is_a: GO:0051350 ! negative regulation of lyase activity created_by: rl creation_date: 2015-05-15T09:55:23Z [Term] id: GO:1904234 name: positive regulation of aconitate hydratase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of aconitate hydratase activity." [GO_REF:0000059, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18160053] subset: gocheck_obsoletion_candidate synonym: "activation of aconitase activity" NARROW [GOC:TermGenie] synonym: "activation of aconitate hydratase activity" NARROW [GOC:TermGenie] synonym: "activation of cis-aconitase activity" NARROW [GOC:TermGenie] synonym: "activation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" NARROW [GOC:TermGenie] synonym: "activation of citrate(isocitrate) hydro-lyase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of aconitase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of cis-aconitase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" EXACT [GOC:TermGenie] synonym: "positive regulation of citrate(isocitrate) hydro-lyase activity" EXACT [GOC:TermGenie] synonym: "up regulation of aconitase activity" EXACT [GOC:TermGenie] synonym: "up regulation of aconitate hydratase activity" EXACT [GOC:TermGenie] synonym: "up regulation of cis-aconitase activity" EXACT [GOC:TermGenie] synonym: "up regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" EXACT [GOC:TermGenie] synonym: "up regulation of citrate(isocitrate) hydro-lyase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of aconitase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of aconitate hydratase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of cis-aconitase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" EXACT [GOC:TermGenie] synonym: "up-regulation of citrate(isocitrate) hydro-lyase activity" EXACT [GOC:TermGenie] synonym: "upregulation of aconitase activity" EXACT [GOC:TermGenie] synonym: "upregulation of aconitate hydratase activity" EXACT [GOC:TermGenie] synonym: "upregulation of cis-aconitase activity" EXACT [GOC:TermGenie] synonym: "upregulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" EXACT [GOC:TermGenie] synonym: "upregulation of citrate(isocitrate) hydro-lyase activity" EXACT [GOC:TermGenie] is_a: GO:0051349 ! positive regulation of lyase activity created_by: rl creation_date: 2015-05-15T09:55:29Z [Term] id: GO:1904246 name: negative regulation of polynucleotide adenylyltransferase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of polynucleotide adenylyltransferase activity." [GO_REF:0000059, GOC:kmv, GOC:TermGenie, PMID:19460348] subset: gocheck_obsoletion_candidate synonym: "down regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "down regulation of AMP polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] synonym: "down regulation of ATP-polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "down regulation of ATP:polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "down regulation of ATP:polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] synonym: "down regulation of NTP polymerase activity" EXACT [GOC:TermGenie] synonym: "down regulation of poly(A) hydrolase activity" EXACT [GOC:TermGenie] synonym: "down regulation of poly(A) polymerase activity" EXACT [GOC:TermGenie] synonym: "down regulation of poly(A) synthetase activity" EXACT [GOC:TermGenie] synonym: "down regulation of poly-A polymerase activity" EXACT [GOC:TermGenie] synonym: "down regulation of polyadenylate nucleotidyltransferase activity" EXACT [GOC:TermGenie] synonym: "down regulation of polyadenylate polymerase activity" EXACT [GOC:TermGenie] synonym: "down regulation of polyadenylate synthetase activity" EXACT [GOC:TermGenie] synonym: "down regulation of polyadenylic acid polymerase activity" EXACT [GOC:TermGenie] synonym: "down regulation of polyadenylic polymerase activity" EXACT [GOC:TermGenie] synonym: "down regulation of polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "down regulation of RNA adenylating enzyme activity" EXACT [GOC:TermGenie] synonym: "down regulation of RNA formation factors, PF1" RELATED [GOC:TermGenie] synonym: "down regulation of terminal riboadenylate transferase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of AMP polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of ATP-polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of ATP:polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of ATP:polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of NTP polymerase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of poly(A) hydrolase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of poly(A) polymerase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of poly(A) synthetase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of poly-A polymerase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of polyadenylate nucleotidyltransferase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of polyadenylate polymerase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of polyadenylate synthetase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of polyadenylic acid polymerase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of polyadenylic polymerase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA adenylating enzyme activity" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA formation factors, PF1" RELATED [GOC:TermGenie] synonym: "down-regulation of terminal riboadenylate transferase activity" EXACT [GOC:TermGenie] synonym: "downregulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "downregulation of AMP polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] synonym: "downregulation of ATP-polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "downregulation of ATP:polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "downregulation of ATP:polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] synonym: "downregulation of NTP polymerase activity" EXACT [GOC:TermGenie] synonym: "downregulation of poly(A) hydrolase activity" EXACT [GOC:TermGenie] synonym: "downregulation of poly(A) polymerase activity" EXACT [GOC:TermGenie] synonym: "downregulation of poly(A) synthetase activity" EXACT [GOC:TermGenie] synonym: "downregulation of poly-A polymerase activity" EXACT [GOC:TermGenie] synonym: "downregulation of polyadenylate nucleotidyltransferase activity" EXACT [GOC:TermGenie] synonym: "downregulation of polyadenylate polymerase activity" EXACT [GOC:TermGenie] synonym: "downregulation of polyadenylate synthetase activity" EXACT [GOC:TermGenie] synonym: "downregulation of polyadenylic acid polymerase activity" EXACT [GOC:TermGenie] synonym: "downregulation of polyadenylic polymerase activity" EXACT [GOC:TermGenie] synonym: "downregulation of polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "downregulation of RNA adenylating enzyme activity" EXACT [GOC:TermGenie] synonym: "downregulation of RNA formation factors, PF1" RELATED [GOC:TermGenie] synonym: "downregulation of terminal riboadenylate transferase activity" EXACT [GOC:TermGenie] synonym: "inhibition of adenosine triphosphate:ribonucleic acid adenylyltransferase activity" NARROW [GOC:TermGenie] synonym: "inhibition of AMP polynucleotidylexotransferase activity" NARROW [GOC:TermGenie] synonym: "inhibition of ATP-polynucleotide adenylyltransferase activity" NARROW [GOC:TermGenie] synonym: "inhibition of ATP:polynucleotide adenylyltransferase activity" NARROW [GOC:TermGenie] synonym: "inhibition of ATP:polynucleotidylexotransferase activity" NARROW [GOC:TermGenie] synonym: "inhibition of NTP polymerase activity" NARROW [GOC:TermGenie] synonym: "inhibition of poly(A) hydrolase activity" NARROW [GOC:TermGenie] synonym: "inhibition of poly(A) polymerase activity" NARROW [GOC:TermGenie] synonym: "inhibition of poly(A) synthetase activity" NARROW [GOC:TermGenie] synonym: "inhibition of poly-A polymerase activity" NARROW [GOC:TermGenie] synonym: "inhibition of polyadenylate nucleotidyltransferase activity" NARROW [GOC:TermGenie] synonym: "inhibition of polyadenylate polymerase activity" NARROW [GOC:TermGenie] synonym: "inhibition of polyadenylate synthetase activity" NARROW [GOC:TermGenie] synonym: "inhibition of polyadenylic acid polymerase activity" NARROW [GOC:TermGenie] synonym: "inhibition of polyadenylic polymerase activity" NARROW [GOC:TermGenie] synonym: "inhibition of polynucleotide adenylyltransferase activity" NARROW [GOC:TermGenie] synonym: "inhibition of RNA adenylating enzyme activity" NARROW [GOC:TermGenie] synonym: "inhibition of RNA formation factors, PF1" RELATED [GOC:TermGenie] synonym: "inhibition of terminal riboadenylate transferase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of AMP polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of ATP-polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of ATP:polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of ATP:polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of NTP polymerase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of poly(A) hydrolase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of poly(A) polymerase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of poly(A) synthetase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of poly-A polymerase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of polyadenylate nucleotidyltransferase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of polyadenylate polymerase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of polyadenylate synthetase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of polyadenylic acid polymerase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of polyadenylic polymerase activity" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA adenylating enzyme activity" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA formation factors, PF1" RELATED [GOC:TermGenie] synonym: "negative regulation of terminal riboadenylate transferase activity" EXACT [GOC:TermGenie] is_a: GO:0051348 ! negative regulation of transferase activity created_by: kmv creation_date: 2015-05-19T14:47:26Z [Term] id: GO:1904247 name: positive regulation of polynucleotide adenylyltransferase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of polynucleotide adenylyltransferase activity." [GO_REF:0000059, GOC:kmv, GOC:TermGenie, PMID:19460348] subset: gocheck_obsoletion_candidate synonym: "activation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity" NARROW [GOC:TermGenie] synonym: "activation of AMP polynucleotidylexotransferase activity" NARROW [GOC:TermGenie] synonym: "activation of ATP-polynucleotide adenylyltransferase activity" NARROW [GOC:TermGenie] synonym: "activation of ATP:polynucleotide adenylyltransferase activity" NARROW [GOC:TermGenie] synonym: "activation of ATP:polynucleotidylexotransferase activity" NARROW [GOC:TermGenie] synonym: "activation of NTP polymerase activity" NARROW [GOC:TermGenie] synonym: "activation of poly(A) hydrolase activity" NARROW [GOC:TermGenie] synonym: "activation of poly(A) polymerase activity" NARROW [GOC:TermGenie] synonym: "activation of poly(A) synthetase activity" NARROW [GOC:TermGenie] synonym: "activation of poly-A polymerase activity" NARROW [GOC:TermGenie] synonym: "activation of polyadenylate nucleotidyltransferase activity" NARROW [GOC:TermGenie] synonym: "activation of polyadenylate polymerase activity" NARROW [GOC:TermGenie] synonym: "activation of polyadenylate synthetase activity" NARROW [GOC:TermGenie] synonym: "activation of polyadenylic acid polymerase activity" NARROW [GOC:TermGenie] synonym: "activation of polyadenylic polymerase activity" NARROW [GOC:TermGenie] synonym: "activation of polynucleotide adenylyltransferase activity" NARROW [GOC:TermGenie] synonym: "activation of RNA adenylating enzyme activity" NARROW [GOC:TermGenie] synonym: "activation of RNA formation factors, PF1" RELATED [GOC:TermGenie] synonym: "activation of terminal riboadenylate transferase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of AMP polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of ATP-polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of ATP:polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of ATP:polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of NTP polymerase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of poly(A) hydrolase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of poly(A) polymerase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of poly(A) synthetase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of poly-A polymerase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of polyadenylate nucleotidyltransferase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of polyadenylate polymerase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of polyadenylate synthetase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of polyadenylic acid polymerase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of polyadenylic polymerase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of RNA adenylating enzyme activity" EXACT [GOC:TermGenie] synonym: "positive regulation of RNA formation factors, PF1" RELATED [GOC:TermGenie] synonym: "positive regulation of terminal riboadenylate transferase activity" EXACT [GOC:TermGenie] synonym: "up regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "up regulation of AMP polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] synonym: "up regulation of ATP-polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "up regulation of ATP:polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "up regulation of ATP:polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] synonym: "up regulation of NTP polymerase activity" EXACT [GOC:TermGenie] synonym: "up regulation of poly(A) hydrolase activity" EXACT [GOC:TermGenie] synonym: "up regulation of poly(A) polymerase activity" EXACT [GOC:TermGenie] synonym: "up regulation of poly(A) synthetase activity" EXACT [GOC:TermGenie] synonym: "up regulation of poly-A polymerase activity" EXACT [GOC:TermGenie] synonym: "up regulation of polyadenylate nucleotidyltransferase activity" EXACT [GOC:TermGenie] synonym: "up regulation of polyadenylate polymerase activity" EXACT [GOC:TermGenie] synonym: "up regulation of polyadenylate synthetase activity" EXACT [GOC:TermGenie] synonym: "up regulation of polyadenylic acid polymerase activity" EXACT [GOC:TermGenie] synonym: "up regulation of polyadenylic polymerase activity" EXACT [GOC:TermGenie] synonym: "up regulation of polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "up regulation of RNA adenylating enzyme activity" EXACT [GOC:TermGenie] synonym: "up regulation of RNA formation factors, PF1" RELATED [GOC:TermGenie] synonym: "up regulation of terminal riboadenylate transferase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of AMP polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of ATP-polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of ATP:polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of ATP:polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of NTP polymerase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of poly(A) hydrolase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of poly(A) polymerase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of poly(A) synthetase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of poly-A polymerase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of polyadenylate nucleotidyltransferase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of polyadenylate polymerase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of polyadenylate synthetase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of polyadenylic acid polymerase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of polyadenylic polymerase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA adenylating enzyme activity" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA formation factors, PF1" RELATED [GOC:TermGenie] synonym: "up-regulation of terminal riboadenylate transferase activity" EXACT [GOC:TermGenie] synonym: "upregulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "upregulation of AMP polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] synonym: "upregulation of ATP-polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "upregulation of ATP:polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "upregulation of ATP:polynucleotidylexotransferase activity" EXACT [GOC:TermGenie] synonym: "upregulation of NTP polymerase activity" EXACT [GOC:TermGenie] synonym: "upregulation of poly(A) hydrolase activity" EXACT [GOC:TermGenie] synonym: "upregulation of poly(A) polymerase activity" EXACT [GOC:TermGenie] synonym: "upregulation of poly(A) synthetase activity" EXACT [GOC:TermGenie] synonym: "upregulation of poly-A polymerase activity" EXACT [GOC:TermGenie] synonym: "upregulation of polyadenylate nucleotidyltransferase activity" EXACT [GOC:TermGenie] synonym: "upregulation of polyadenylate polymerase activity" EXACT [GOC:TermGenie] synonym: "upregulation of polyadenylate synthetase activity" EXACT [GOC:TermGenie] synonym: "upregulation of polyadenylic acid polymerase activity" EXACT [GOC:TermGenie] synonym: "upregulation of polyadenylic polymerase activity" EXACT [GOC:TermGenie] synonym: "upregulation of polynucleotide adenylyltransferase activity" EXACT [GOC:TermGenie] synonym: "upregulation of RNA adenylating enzyme activity" EXACT [GOC:TermGenie] synonym: "upregulation of RNA formation factors, PF1" RELATED [GOC:TermGenie] synonym: "upregulation of terminal riboadenylate transferase activity" EXACT [GOC:TermGenie] is_a: GO:0051347 ! positive regulation of transferase activity created_by: kmv creation_date: 2015-05-19T14:47:32Z [Term] id: GO:1904285 name: regulation of protein-pyridoxal-5-phosphate linkage namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage." [GO_REF:0000058, GOC:TermGenie, PMID:25957689] subset: gocheck_obsoletion_candidate relationship: regulates GO:0018352 ! protein-pyridoxal-5-phosphate linkage created_by: mcc creation_date: 2015-06-05T17:21:14Z [Term] id: GO:1904286 name: negative regulation of protein-pyridoxal-5-phosphate linkage namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage." [GO_REF:0000058, GOC:TermGenie, PMID:25957689] subset: gocheck_obsoletion_candidate synonym: "down regulation of protein-pyridoxal-5-phosphate linkage" EXACT [GOC:TermGenie] synonym: "down-regulation of protein-pyridoxal-5-phosphate linkage" EXACT [GOC:TermGenie] synonym: "downregulation of protein-pyridoxal-5-phosphate linkage" EXACT [GOC:TermGenie] synonym: "inhibition of protein-pyridoxal-5-phosphate linkage" NARROW [GOC:TermGenie] is_a: GO:0031400 ! negative regulation of protein modification process is_a: GO:1904285 ! regulation of protein-pyridoxal-5-phosphate linkage relationship: negatively_regulates GO:0018352 ! protein-pyridoxal-5-phosphate linkage created_by: mcc creation_date: 2015-06-05T17:21:21Z [Term] id: GO:1904287 name: positive regulation of protein-pyridoxal-5-phosphate linkage namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage." [GO_REF:0000058, GOC:TermGenie, PMID:25957689] subset: gocheck_obsoletion_candidate synonym: "activation of protein-pyridoxal-5-phosphate linkage" NARROW [GOC:TermGenie] synonym: "stimulation of protein-pyridoxal-5-phosphate linkage" EXACT [] synonym: "up regulation of protein-pyridoxal-5-phosphate linkage" EXACT [GOC:TermGenie] synonym: "up-regulation of protein-pyridoxal-5-phosphate linkage" EXACT [GOC:TermGenie] synonym: "upregulation of protein-pyridoxal-5-phosphate linkage" EXACT [GOC:TermGenie] is_a: GO:0031401 ! positive regulation of protein modification process is_a: GO:1904285 ! regulation of protein-pyridoxal-5-phosphate linkage relationship: positively_regulates GO:0018352 ! protein-pyridoxal-5-phosphate linkage created_by: mcc creation_date: 2015-06-05T17:21:28Z [Term] id: GO:1904323 name: regulation of inhibitory G protein-coupled receptor phosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation." [GO_REF:0000058, GOC:TermGenie, PMID:15937517] subset: gocheck_obsoletion_candidate synonym: "regulation of inhibitory G-protein coupled receptor phosphorylation" EXACT [] is_a: GO:0001932 ! regulation of protein phosphorylation relationship: regulates GO:0002030 ! inhibitory G protein-coupled receptor phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI created_by: sl creation_date: 2015-06-10T19:46:37Z [Term] id: GO:1904324 name: negative regulation of inhibitory G protein-coupled receptor phosphorylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation." [GO_REF:0000058, GOC:TermGenie, PMID:15937517] subset: gocheck_obsoletion_candidate synonym: "down regulation of inhibitory G-protein coupled receptor phosphorylation" EXACT [GOC:TermGenie] synonym: "down-regulation of inhibitory G-protein coupled receptor phosphorylation" EXACT [GOC:TermGenie] synonym: "downregulation of inhibitory G-protein coupled receptor phosphorylation" EXACT [GOC:TermGenie] synonym: "inhibition of inhibitory G-protein coupled receptor phosphorylation" NARROW [GOC:TermGenie] synonym: "negative regulation of inhibitory G-protein coupled receptor phosphorylation" EXACT [] is_a: GO:0001933 ! negative regulation of protein phosphorylation is_a: GO:1904323 ! regulation of inhibitory G protein-coupled receptor phosphorylation relationship: negatively_regulates GO:0002030 ! inhibitory G protein-coupled receptor phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI created_by: sl creation_date: 2015-06-10T19:46:43Z [Term] id: GO:1904325 name: positive regulation of inhibitory G protein-coupled receptor phosphorylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation." [GO_REF:0000058, GOC:TermGenie, PMID:15937517] subset: gocheck_obsoletion_candidate synonym: "activation of inhibitory G-protein coupled receptor phosphorylation" NARROW [GOC:TermGenie] synonym: "positive regulation of inhibitory G-protein coupled receptor phosphorylation" EXACT [] synonym: "up regulation of inhibitory G-protein coupled receptor phosphorylation" EXACT [GOC:TermGenie] synonym: "up-regulation of inhibitory G-protein coupled receptor phosphorylation" EXACT [GOC:TermGenie] synonym: "upregulation of inhibitory G-protein coupled receptor phosphorylation" EXACT [GOC:TermGenie] is_a: GO:0001934 ! positive regulation of protein phosphorylation is_a: GO:1904323 ! regulation of inhibitory G protein-coupled receptor phosphorylation relationship: positively_regulates GO:0002030 ! inhibitory G protein-coupled receptor phosphorylation property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28278" xsd:anyURI created_by: sl creation_date: 2015-06-10T19:46:50Z [Term] id: GO:1904382 name: mannose trimming involved in glycoprotein ERAD pathway namespace: biological_process def: "The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein that occurs as part of glycoprotein ER-associated glycoprotein degradation (gpERAD)." [GO_REF:0000060, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24519966] subset: gocheck_obsoletion_candidate synonym: "glycoprotein mannose trimming involved in ER-associated glycoprotein degradation" RELATED [GOC:TermGenie] synonym: "glycoprotein mannose trimming involved in glycoprotein ERAD" RELATED [GOC:TermGenie] synonym: "glycoprotein mannose trimming involved in glycoprotein ERAD pathway" RELATED [GOC:TermGenie] synonym: "glycoprotein mannose trimming involved in gpERAD" RELATED [GOC:TermGenie] synonym: "mannose trimming involved in misfolded or incompletely synthesized glycoprotein catabolic process" BROAD [GOC:TermGenie] synonym: "protein alpha-1,2-demannosylation involved in ER-associated glycoprotein degradation" EXACT [GOC:TermGenie] synonym: "protein alpha-1,2-demannosylation involved in glycoprotein ERAD" EXACT [GOC:TermGenie] synonym: "protein alpha-1,2-demannosylation involved in glycoprotein ERAD pathway" EXACT [GOC:bf] synonym: "protein alpha-1,2-demannosylation involved in gpERAD" EXACT [GOC:TermGenie] is_a: GO:0035977 ! protein deglycosylation involved in glycoprotein catabolic process is_a: GO:0036508 ! protein alpha-1,2-demannosylation created_by: bf creation_date: 2015-06-23T09:46:55Z [Term] id: GO:1904451 name: regulation of potassium:proton exchanging ATPase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity." [GO_REF:0000059, GOC:TermGenie, PMID:11897793] subset: gocheck_obsoletion_candidate synonym: "regulation of (K+ + H+)-ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of ATP phosphohydrolase (H+/K+-exchanging)" EXACT [GOC:TermGenie] synonym: "regulation of gastric H+/K(+) ATPase activity" NARROW [GOC:TermGenie] synonym: "regulation of gastric H+/K+ ATPase" NARROW [GOC:TermGenie] synonym: "regulation of H+-K+-ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of H+/K(+)-ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of H+/K(+)-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of H+/K+-ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of H+/K+-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of H,K-ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of hydrogen/potassium-exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of hydrogen:potassium exchanging ATPase activity" EXACT [GOC:TermGenie] synonym: "regulation of hydrogen:potassium-exchanging ATPase activity" EXACT [] synonym: "regulation of proton pump activity" BROAD [GOC:TermGenie] is_a: GO:0043462 ! regulation of ATP-dependent activity is_a: GO:1901016 ! regulation of potassium ion transmembrane transporter activity created_by: sl creation_date: 2015-07-08T23:00:03Z [Term] id: GO:1904604 name: negative regulation of advanced glycation end-product receptor activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of advanced glycation end-product receptor activity." [GO_REF:0000059, GOC:krc, GOC:TermGenie, PMID:16503878] subset: gocheck_obsoletion_candidate synonym: "down regulation of advanced glycation end-product receptor activity" EXACT [GOC:TermGenie] synonym: "down regulation of AGE receptor activity" EXACT [GOC:TermGenie] synonym: "down regulation of RAGE activity" EXACT [GOC:TermGenie] synonym: "down-regulation of advanced glycation end-product receptor activity" EXACT [GOC:TermGenie] synonym: "down-regulation of AGE receptor activity" EXACT [GOC:TermGenie] synonym: "down-regulation of RAGE activity" EXACT [GOC:TermGenie] synonym: "downregulation of advanced glycation end-product receptor activity" EXACT [GOC:TermGenie] synonym: "downregulation of AGE receptor activity" EXACT [GOC:TermGenie] synonym: "downregulation of RAGE activity" EXACT [GOC:TermGenie] synonym: "inhibition of advanced glycation end-product receptor activity" NARROW [GOC:TermGenie] synonym: "inhibition of AGE receptor activity" NARROW [GOC:TermGenie] synonym: "inhibition of RAGE activity" NARROW [GOC:TermGenie] synonym: "negative regulation of AGE receptor activity" EXACT [GOC:TermGenie] synonym: "negative regulation of RAGE activity" EXACT [GOC:TermGenie] is_a: GO:2000272 ! negative regulation of signaling receptor activity created_by: krc creation_date: 2015-08-26T16:24:56Z [Term] id: GO:1904663 name: regulation of N-terminal peptidyl-methionine acetylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of N-terminal peptidyl-methionine acetylation." [GO_REF:0000058, GOC:TermGenie, PMID:20807799] subset: gocheck_obsoletion_candidate is_a: GO:1901983 ! regulation of protein acetylation relationship: regulates GO:0017196 ! N-terminal peptidyl-methionine acetylation created_by: vw creation_date: 2015-09-07T19:18:49Z [Term] id: GO:1904664 name: negative regulation of N-terminal peptidyl-methionine acetylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-methionine acetylation." [GO_REF:0000058, GOC:TermGenie, PMID:20807799] subset: gocheck_obsoletion_candidate is_a: GO:1901984 ! negative regulation of protein acetylation is_a: GO:1904663 ! regulation of N-terminal peptidyl-methionine acetylation relationship: negatively_regulates GO:0017196 ! N-terminal peptidyl-methionine acetylation created_by: vw creation_date: 2015-09-07T19:18:56Z [Term] id: GO:1904665 name: positive regulation of N-terminal peptidyl-methionine acetylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-methionine acetylation." [GO_REF:0000058, GOC:TermGenie, PMID:20807799] subset: gocheck_obsoletion_candidate is_a: GO:1901985 ! positive regulation of protein acetylation is_a: GO:1904663 ! regulation of N-terminal peptidyl-methionine acetylation relationship: positively_regulates GO:0017196 ! N-terminal peptidyl-methionine acetylation created_by: vw creation_date: 2015-09-07T19:19:02Z [Term] id: GO:1904666 name: regulation of ubiquitin protein ligase activity namespace: biological_process alt_id: GO:1903834 def: "Any process that modulates the frequency, rate or extent of ubiquitin protein ligase activity." [GO_REF:0000059, GOC:dph, GOC:TermGenie, GOC:vw, PMID:10921876, PMID:26216882] subset: gocheck_obsoletion_candidate synonym: "regulation of APC-fizzy related complex activity" NARROW [] synonym: "regulation of E3" RELATED [GOC:TermGenie] synonym: "regulation of protein ubiquitination activity" EXACT [GOC:TermGenie] synonym: "regulation of ubiquitin ligase activity" EXACT [GOC:TermGenie] is_a: GO:0051438 ! regulation of ubiquitin-protein transferase activity created_by: dph creation_date: 2015-09-08T15:26:59Z [Term] id: GO:1904667 name: negative regulation of ubiquitin protein ligase activity namespace: biological_process alt_id: GO:0060564 alt_id: GO:1904190 def: "Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin protein ligase activity." [GO_REF:0000059, GOC:dph, GOC:tb, GOC:TermGenie, PMID:26216882] subset: gocheck_obsoletion_candidate synonym: "down regulation of E3" RELATED [GOC:TermGenie] synonym: "down regulation of protein ubiquitination activity" EXACT [GOC:TermGenie] synonym: "down regulation of ubiquitin ligase activity" EXACT [GOC:TermGenie] synonym: "down regulation of ubiquitin protein ligase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of E3" RELATED [GOC:TermGenie] synonym: "down-regulation of protein ubiquitination activity" EXACT [GOC:TermGenie] synonym: "down-regulation of ubiquitin ligase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of ubiquitin protein ligase activity" EXACT [GOC:TermGenie] synonym: "downregulation of E3" RELATED [GOC:TermGenie] synonym: "downregulation of protein ubiquitination activity" EXACT [GOC:TermGenie] synonym: "downregulation of ubiquitin ligase activity" EXACT [GOC:TermGenie] synonym: "downregulation of ubiquitin protein ligase activity" EXACT [GOC:TermGenie] synonym: "inhibition of E3" RELATED [GOC:TermGenie] synonym: "inhibition of protein ubiquitination activity" NARROW [GOC:TermGenie] synonym: "inhibition of ubiquitin ligase activity" NARROW [GOC:TermGenie] synonym: "inhibition of ubiquitin protein ligase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of anaphase-promoting complex activity during mitotic cell cycle" RELATED [GOC:dph, GOC:tb] synonym: "negative regulation of APC activity during mitotic cell cycle" RELATED [GOC:dph, GOC:tb] synonym: "negative regulation of APC-Cdc20 complex activity" NARROW [] synonym: "negative regulation of APC-fizzy related complex activity" NARROW [] synonym: "negative regulation of APC/C activity during mitotic cell cycle" RELATED [GOC:dph, GOC:tb] synonym: "negative regulation of cyclosome activity during mitotic cell cycle" RELATED [GOC:dph, GOC:tb] synonym: "negative regulation of E3" RELATED [GOC:TermGenie] synonym: "negative regulation of mitotic anaphase-promoting complex activity" RELATED [GOC:vw] synonym: "negative regulation of protein ubiquitination activity" EXACT [GOC:TermGenie] synonym: "negative regulation of ubiquitin ligase activity" EXACT [GOC:TermGenie] is_a: GO:0051444 ! negative regulation of ubiquitin-protein transferase activity is_a: GO:1904666 ! regulation of ubiquitin protein ligase activity created_by: dph creation_date: 2015-09-08T15:27:05Z [Term] id: GO:1904668 name: positive regulation of ubiquitin protein ligase activity namespace: biological_process alt_id: GO:0007092 alt_id: GO:0051488 alt_id: GO:0090623 alt_id: GO:1903835 def: "Any process that activates or increases the frequency, rate or extent of ubiquitin protein ligase activity." [GO_REF:0000059, GOC:dph, GOC:TermGenie, GOC:vw, PMID:10921876, PMID:26216882] subset: gocheck_obsoletion_candidate synonym: "activation of anaphase-promoting complex activity" NARROW [] synonym: "activation of APC-Cdc20 complex activity" NARROW [] synonym: "activation of APC-fizzy related complex activity" NARROW [] synonym: "activation of E3" RELATED [GOC:TermGenie] synonym: "activation of protein ubiquitination activity" NARROW [GOC:TermGenie] synonym: "activation of ubiquitin ligase activity" NARROW [GOC:TermGenie] synonym: "activation of ubiquitin protein ligase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of APC-fizzy related complex activity" NARROW [] synonym: "positive regulation of E3" RELATED [GOC:TermGenie] synonym: "positive regulation of protein ubiquitination activity" EXACT [GOC:TermGenie] synonym: "positive regulation of ubiquitin ligase activity" RELATED [GOC:TermGenie] synonym: "up regulation of APC-fizzy related complex activity" NARROW [GOC:TermGenie] synonym: "up regulation of E3" RELATED [GOC:TermGenie] synonym: "up regulation of protein ubiquitination activity" EXACT [GOC:TermGenie] synonym: "up regulation of ubiquitin ligase activity" EXACT [GOC:TermGenie] synonym: "up regulation of ubiquitin protein ligase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of APC-fizzy related complex activity" NARROW [GOC:TermGenie] synonym: "up-regulation of E3" RELATED [GOC:TermGenie] synonym: "up-regulation of protein ubiquitination activity" EXACT [GOC:TermGenie] synonym: "up-regulation of ubiquitin ligase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of ubiquitin protein ligase activity" EXACT [GOC:TermGenie] synonym: "upregulation of APC-fizzy related complex activity" NARROW [GOC:TermGenie] synonym: "upregulation of E3" RELATED [GOC:TermGenie] synonym: "upregulation of protein ubiquitination activity" EXACT [GOC:TermGenie] synonym: "upregulation of ubiquitin ligase activity" EXACT [GOC:TermGenie] synonym: "upregulation of ubiquitin protein ligase activity" EXACT [GOC:TermGenie] is_a: GO:0051443 ! positive regulation of ubiquitin-protein transferase activity is_a: GO:1904666 ! regulation of ubiquitin protein ligase activity created_by: dph creation_date: 2015-09-08T15:27:11Z [Term] id: GO:1904683 name: regulation of metalloendopeptidase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of metalloendopeptidase activity." [GO_REF:0000059, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:18591254] subset: gocheck_obsoletion_candidate synonym: "regulation of metalloendoprotease activity" NARROW [GOC:TermGenie] synonym: "regulation of metalloendoproteinase activity" NARROW [GOC:TermGenie] is_a: GO:0052548 ! regulation of endopeptidase activity is_a: GO:1905048 ! regulation of metallopeptidase activity created_by: rph creation_date: 2015-09-24T11:18:14Z [Term] id: GO:1904684 name: negative regulation of metalloendopeptidase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of metalloendopeptidase activity." [GO_REF:0000059, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:18591254] subset: gocheck_obsoletion_candidate synonym: "down regulation of metalloendopeptidase activity" EXACT [GOC:TermGenie] synonym: "down regulation of metalloendoprotease activity" NARROW [GOC:TermGenie] synonym: "down regulation of metalloendoproteinase activity" NARROW [GOC:TermGenie] synonym: "down-regulation of metalloendopeptidase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of metalloendoprotease activity" NARROW [GOC:TermGenie] synonym: "down-regulation of metalloendoproteinase activity" NARROW [GOC:TermGenie] synonym: "downregulation of metalloendopeptidase activity" EXACT [GOC:TermGenie] synonym: "downregulation of metalloendoprotease activity" NARROW [GOC:TermGenie] synonym: "downregulation of metalloendoproteinase activity" NARROW [GOC:TermGenie] synonym: "inhibition of metalloendopeptidase activity" NARROW [GOC:TermGenie] synonym: "inhibition of metalloendoprotease activity" NARROW [GOC:TermGenie] synonym: "inhibition of metalloendoproteinase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of metalloendoprotease activity" EXACT [GOC:TermGenie] synonym: "negative regulation of metalloendoproteinase activity" NARROW [GOC:TermGenie] is_a: GO:0010951 ! negative regulation of endopeptidase activity is_a: GO:1904683 ! regulation of metalloendopeptidase activity is_a: GO:1905049 ! negative regulation of metallopeptidase activity created_by: rph creation_date: 2015-09-24T11:18:21Z [Term] id: GO:1904685 name: positive regulation of metalloendopeptidase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity." [GO_REF:0000059, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:18591254] subset: gocheck_obsoletion_candidate synonym: "activation of metalloendopeptidase activity" NARROW [GOC:TermGenie] synonym: "activation of metalloendoprotease activity" NARROW [GOC:TermGenie] synonym: "activation of metalloendoproteinase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of metalloendoprotease activity" NARROW [GOC:TermGenie] synonym: "positive regulation of metalloendoproteinase activity" NARROW [GOC:TermGenie] synonym: "up regulation of metalloendopeptidase activity" EXACT [GOC:TermGenie] synonym: "up regulation of metalloendoprotease activity" NARROW [GOC:TermGenie] synonym: "up regulation of metalloendoproteinase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of metalloendopeptidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of metalloendoprotease activity" NARROW [GOC:TermGenie] synonym: "up-regulation of metalloendoproteinase activity" NARROW [GOC:TermGenie] synonym: "upregulation of metalloendopeptidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of metalloendoprotease activity" NARROW [GOC:TermGenie] synonym: "upregulation of metalloendoproteinase activity" NARROW [GOC:TermGenie] is_a: GO:0010950 ! positive regulation of endopeptidase activity is_a: GO:1904683 ! regulation of metalloendopeptidase activity is_a: GO:1905050 ! positive regulation of metallopeptidase activity created_by: rph creation_date: 2015-09-24T11:18:28Z [Term] id: GO:1904782 name: negative regulation of NMDA glutamate receptor activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of NMDA glutamate receptor activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:12857] subset: gocheck_obsoletion_candidate synonym: "down regulation of N-methyl-D-aspartate selective glutamate receptor activity" EXACT [GOC:TermGenie] synonym: "down regulation of NMDA glutamate receptor activity" EXACT [GOC:TermGenie] synonym: "down regulation of NMDA receptor" EXACT [GOC:TermGenie] synonym: "down-regulation of N-methyl-D-aspartate selective glutamate receptor activity" EXACT [GOC:TermGenie] synonym: "down-regulation of NMDA glutamate receptor activity" EXACT [GOC:TermGenie] synonym: "down-regulation of NMDA receptor" EXACT [GOC:TermGenie] synonym: "downregulation of N-methyl-D-aspartate selective glutamate receptor activity" EXACT [GOC:TermGenie] synonym: "downregulation of NMDA glutamate receptor activity" EXACT [GOC:TermGenie] synonym: "downregulation of NMDA receptor" EXACT [GOC:TermGenie] synonym: "inhibition of N-methyl-D-aspartate selective glutamate receptor activity" NARROW [GOC:TermGenie] synonym: "inhibition of NMDA glutamate receptor activity" NARROW [GOC:TermGenie] synonym: "inhibition of NMDA receptor" NARROW [GOC:TermGenie] synonym: "negative regulation of N-methyl-D-aspartate selective glutamate receptor activity" EXACT [GOC:TermGenie] synonym: "negative regulation of NMDA receptor" EXACT [GOC:TermGenie] is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity is_a: GO:2000272 ! negative regulation of signaling receptor activity is_a: GO:2000310 ! regulation of NMDA receptor activity created_by: mr creation_date: 2015-10-30T19:39:31Z [Term] id: GO:1904783 name: positive regulation of NMDA glutamate receptor activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of NMDA glutamate receptor activity." [GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:12857] subset: gocheck_obsoletion_candidate synonym: "activation of N-methyl-D-aspartate selective glutamate receptor activity" NARROW [GOC:TermGenie] synonym: "activation of NMDA glutamate receptor activity" NARROW [GOC:TermGenie] synonym: "activation of NMDA receptor" NARROW [GOC:TermGenie] synonym: "positive regulation of N-methyl-D-aspartate selective glutamate receptor activity" EXACT [GOC:TermGenie] synonym: "positive regulation of NMDA receptor" EXACT [GOC:TermGenie] synonym: "up regulation of N-methyl-D-aspartate selective glutamate receptor activity" EXACT [GOC:TermGenie] synonym: "up regulation of NMDA glutamate receptor activity" EXACT [GOC:TermGenie] synonym: "up regulation of NMDA receptor" EXACT [GOC:TermGenie] synonym: "up-regulation of N-methyl-D-aspartate selective glutamate receptor activity" EXACT [GOC:TermGenie] synonym: "up-regulation of NMDA glutamate receptor activity" EXACT [GOC:TermGenie] synonym: "up-regulation of NMDA receptor" EXACT [GOC:TermGenie] synonym: "upregulation of N-methyl-D-aspartate selective glutamate receptor activity" EXACT [GOC:TermGenie] synonym: "upregulation of NMDA glutamate receptor activity" EXACT [GOC:TermGenie] synonym: "upregulation of NMDA receptor" EXACT [GOC:TermGenie] is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity is_a: GO:2000273 ! positive regulation of signaling receptor activity is_a: GO:2000310 ! regulation of NMDA receptor activity created_by: mr creation_date: 2015-10-30T19:39:37Z [Term] id: GO:1904806 name: regulation of protein oxidation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein oxidation." [GO_REF:0000058, GOC:TermGenie, PMID:22719267] subset: gocheck_obsoletion_candidate synonym: "regulation of protein amino acid oxidation" EXACT [GOC:TermGenie] relationship: regulates GO:0018158 ! protein oxidation created_by: mec creation_date: 2015-11-10T14:06:00Z [Term] id: GO:1904807 name: negative regulation of protein oxidation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein oxidation." [GO_REF:0000058, GOC:TermGenie, PMID:22719267] subset: gocheck_obsoletion_candidate synonym: "down regulation of protein amino acid oxidation" EXACT [GOC:TermGenie] synonym: "down regulation of protein oxidation" EXACT [GOC:TermGenie] synonym: "down-regulation of protein amino acid oxidation" EXACT [GOC:TermGenie] synonym: "down-regulation of protein oxidation" EXACT [GOC:TermGenie] synonym: "downregulation of protein amino acid oxidation" EXACT [GOC:TermGenie] synonym: "downregulation of protein oxidation" EXACT [GOC:TermGenie] synonym: "inhibition of protein amino acid oxidation" NARROW [GOC:TermGenie] synonym: "inhibition of protein oxidation" NARROW [GOC:TermGenie] synonym: "negative regulation of protein amino acid oxidation" EXACT [GOC:TermGenie] is_a: GO:0031400 ! negative regulation of protein modification process is_a: GO:1904806 ! regulation of protein oxidation relationship: negatively_regulates GO:0018158 ! protein oxidation created_by: mec creation_date: 2015-11-10T14:06:08Z [Term] id: GO:1904808 name: positive regulation of protein oxidation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein oxidation." [GO_REF:0000058, GOC:TermGenie, PMID:22719267] subset: gocheck_obsoletion_candidate synonym: "activation of protein amino acid oxidation" NARROW [GOC:TermGenie] synonym: "activation of protein oxidation" NARROW [GOC:TermGenie] synonym: "positive regulation of protein amino acid oxidation" EXACT [GOC:TermGenie] synonym: "up regulation of protein amino acid oxidation" EXACT [GOC:TermGenie] synonym: "up regulation of protein oxidation" EXACT [GOC:TermGenie] synonym: "up-regulation of protein amino acid oxidation" EXACT [GOC:TermGenie] synonym: "up-regulation of protein oxidation" EXACT [GOC:TermGenie] synonym: "upregulation of protein amino acid oxidation" EXACT [GOC:TermGenie] synonym: "upregulation of protein oxidation" EXACT [GOC:TermGenie] is_a: GO:0031401 ! positive regulation of protein modification process is_a: GO:1904806 ! regulation of protein oxidation relationship: positively_regulates GO:0018158 ! protein oxidation created_by: mec creation_date: 2015-11-10T14:06:15Z [Term] id: GO:1904959 name: regulation of cytochrome-c oxidase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cytochrome-c oxidase activity." [GO_REF:0000059, GOC:TermGenie, PMID:26734017] subset: gocheck_obsoletion_candidate synonym: "regulation of aa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "regulation of ba3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "regulation of caa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "regulation of cbb3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "regulation of complex IV (mitochondrial electron transport) activity" RELATED [GOC:TermGenie] synonym: "regulation of cytochrome a3 activity" NARROW [GOC:TermGenie] synonym: "regulation of cytochrome aa3 activity" NARROW [GOC:TermGenie] synonym: "regulation of cytochrome c oxidase activity" EXACT [GOC:TermGenie] synonym: "regulation of cytochrome oxidase activity" RELATED [GOC:TermGenie] synonym: "regulation of ferrocytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "regulation of ferrocytochrome-c:oxygen oxidoreductase" NARROW [GOC:TermGenie] synonym: "regulation of indophenol oxidase" NARROW [GOC:TermGenie] synonym: "regulation of indophenolase" NARROW [GOC:TermGenie] synonym: "regulation of NADH cytochrome c oxidase" EXACT [GOC:TermGenie] synonym: "regulation of warburg's respiratory enzyme activity" RELATED [GOC:TermGenie] is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity is_a: GO:0051341 ! regulation of oxidoreductase activity created_by: tb creation_date: 2016-02-09T22:18:27Z [Term] id: GO:1904960 name: positive regulation of cytochrome-c oxidase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cytochrome-c oxidase activity." [GO_REF:0000059, GOC:TermGenie, PMID:26734017] subset: gocheck_obsoletion_candidate synonym: "activation of aa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "activation of ba3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "activation of caa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "activation of cbb3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "activation of complex IV (mitochondrial electron transport) activity" RELATED [GOC:TermGenie] synonym: "activation of cytochrome a3 activity" NARROW [GOC:TermGenie] synonym: "activation of cytochrome aa3 activity" NARROW [GOC:TermGenie] synonym: "activation of cytochrome c oxidase activity" NARROW [GOC:TermGenie] synonym: "activation of cytochrome oxidase activity" RELATED [GOC:TermGenie] synonym: "activation of cytochrome-c oxidase activity" NARROW [GOC:TermGenie] synonym: "activation of ferrocytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "activation of ferrocytochrome-c:oxygen oxidoreductase" NARROW [GOC:TermGenie] synonym: "activation of indophenol oxidase" NARROW [GOC:TermGenie] synonym: "activation of indophenolase" NARROW [GOC:TermGenie] synonym: "activation of NADH cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "activation of warburg's respiratory enzyme activity" RELATED [GOC:TermGenie] synonym: "positive regulation of aa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "positive regulation of ba3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "positive regulation of caa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "positive regulation of cbb3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "positive regulation of complex IV (mitochondrial electron transport) activity" RELATED [GOC:TermGenie] synonym: "positive regulation of cytochrome a3 activity" NARROW [GOC:TermGenie] synonym: "positive regulation of cytochrome aa3 activity" NARROW [GOC:TermGenie] synonym: "positive regulation of cytochrome c oxidase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of cytochrome oxidase activity" RELATED [GOC:TermGenie] synonym: "positive regulation of ferrocytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "positive regulation of ferrocytochrome-c:oxygen oxidoreductase" NARROW [GOC:TermGenie] synonym: "positive regulation of indophenol oxidase" NARROW [GOC:TermGenie] synonym: "positive regulation of indophenolase" NARROW [GOC:TermGenie] synonym: "positive regulation of NADH cytochrome c oxidase" EXACT [GOC:TermGenie] synonym: "positive regulation of warburg's respiratory enzyme activity" RELATED [GOC:TermGenie] synonym: "up regulation of aa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "up regulation of ba3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "up regulation of caa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "up regulation of cbb3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "up regulation of complex IV (mitochondrial electron transport) activity" RELATED [GOC:TermGenie] synonym: "up regulation of cytochrome a3 activity" NARROW [GOC:TermGenie] synonym: "up regulation of cytochrome aa3 activity" NARROW [GOC:TermGenie] synonym: "up regulation of cytochrome c oxidase activity" EXACT [GOC:TermGenie] synonym: "up regulation of cytochrome oxidase activity" RELATED [GOC:TermGenie] synonym: "up regulation of cytochrome-c oxidase activity" EXACT [GOC:TermGenie] synonym: "up regulation of ferrocytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "up regulation of ferrocytochrome-c:oxygen oxidoreductase" NARROW [GOC:TermGenie] synonym: "up regulation of indophenol oxidase" NARROW [GOC:TermGenie] synonym: "up regulation of indophenolase" NARROW [GOC:TermGenie] synonym: "up regulation of NADH cytochrome c oxidase" EXACT [GOC:TermGenie] synonym: "up regulation of warburg's respiratory enzyme activity" RELATED [GOC:TermGenie] synonym: "up-regulation of aa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "up-regulation of ba3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "up-regulation of caa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "up-regulation of cbb3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "up-regulation of complex IV (mitochondrial electron transport) activity" RELATED [GOC:TermGenie] synonym: "up-regulation of cytochrome a3 activity" NARROW [GOC:TermGenie] synonym: "up-regulation of cytochrome aa3 activity" NARROW [GOC:TermGenie] synonym: "up-regulation of cytochrome c oxidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of cytochrome oxidase activity" RELATED [GOC:TermGenie] synonym: "up-regulation of cytochrome-c oxidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of ferrocytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "up-regulation of ferrocytochrome-c:oxygen oxidoreductase" NARROW [GOC:TermGenie] synonym: "up-regulation of indophenol oxidase" NARROW [GOC:TermGenie] synonym: "up-regulation of indophenolase" NARROW [GOC:TermGenie] synonym: "up-regulation of NADH cytochrome c oxidase" EXACT [GOC:TermGenie] synonym: "up-regulation of warburg's respiratory enzyme activity" RELATED [GOC:TermGenie] synonym: "upregulation of aa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "upregulation of ba3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "upregulation of caa3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "upregulation of cbb3-type cytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "upregulation of complex IV (mitochondrial electron transport) activity" RELATED [GOC:TermGenie] synonym: "upregulation of cytochrome a3 activity" NARROW [GOC:TermGenie] synonym: "upregulation of cytochrome aa3 activity" NARROW [GOC:TermGenie] synonym: "upregulation of cytochrome c oxidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of cytochrome oxidase activity" RELATED [GOC:TermGenie] synonym: "upregulation of cytochrome-c oxidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of ferrocytochrome c oxidase" NARROW [GOC:TermGenie] synonym: "upregulation of ferrocytochrome-c:oxygen oxidoreductase" NARROW [GOC:TermGenie] synonym: "upregulation of indophenol oxidase" NARROW [GOC:TermGenie] synonym: "upregulation of indophenolase" NARROW [GOC:TermGenie] synonym: "upregulation of NADH cytochrome c oxidase" EXACT [GOC:TermGenie] synonym: "upregulation of warburg's respiratory enzyme activity" RELATED [GOC:TermGenie] is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity is_a: GO:0051353 ! positive regulation of oxidoreductase activity is_a: GO:1904959 ! regulation of cytochrome-c oxidase activity created_by: tb creation_date: 2016-02-09T22:18:43Z [Term] id: GO:1905048 name: regulation of metallopeptidase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of metallopeptidase activity." [GO_REF:0000059, GOC:TermGenie, PMID:26473732] subset: gocheck_obsoletion_candidate synonym: "regulation of metalloprotease activity" NARROW [GOC:TermGenie] synonym: "regulation of metalloproteinase activity" NARROW [GOC:TermGenie] is_a: GO:0052547 ! regulation of peptidase activity created_by: mm2 creation_date: 2016-03-15T16:44:27Z [Term] id: GO:1905049 name: negative regulation of metallopeptidase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of metallopeptidase activity." [GO_REF:0000059, GOC:TermGenie, PMID:26473732] subset: gocheck_obsoletion_candidate synonym: "down regulation of metallopeptidase activity" EXACT [GOC:TermGenie] synonym: "down regulation of metalloprotease activity" NARROW [GOC:TermGenie] synonym: "down regulation of metalloproteinase activity" NARROW [GOC:TermGenie] synonym: "down-regulation of metallopeptidase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of metalloprotease activity" NARROW [GOC:TermGenie] synonym: "down-regulation of metalloproteinase activity" NARROW [GOC:TermGenie] synonym: "downregulation of metallopeptidase activity" EXACT [GOC:TermGenie] synonym: "downregulation of metalloprotease activity" NARROW [GOC:TermGenie] synonym: "downregulation of metalloproteinase activity" NARROW [GOC:TermGenie] synonym: "inhibition of metallopeptidase activity" NARROW [GOC:TermGenie] synonym: "inhibition of metalloprotease activity" NARROW [GOC:TermGenie] synonym: "inhibition of metalloproteinase activity" NARROW [GOC:TermGenie] synonym: "negative regulation of metalloprotease activity" NARROW [GOC:TermGenie] synonym: "negative regulation of metalloproteinase activity" NARROW [GOC:TermGenie] is_a: GO:0010466 ! negative regulation of peptidase activity is_a: GO:1905048 ! regulation of metallopeptidase activity created_by: mm2 creation_date: 2016-03-15T16:44:37Z [Term] id: GO:1905050 name: positive regulation of metallopeptidase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of metallopeptidase activity." [GO_REF:0000059, GOC:TermGenie, PMID:26473732] subset: gocheck_obsoletion_candidate synonym: "activation of metallopeptidase activity" NARROW [GOC:TermGenie] synonym: "activation of metalloprotease activity" NARROW [GOC:TermGenie] synonym: "activation of metalloproteinase activity" NARROW [GOC:TermGenie] synonym: "positive regulation of metalloprotease activity" NARROW [GOC:TermGenie] synonym: "positive regulation of metalloproteinase activity" NARROW [GOC:TermGenie] synonym: "up regulation of metallopeptidase activity" EXACT [GOC:TermGenie] synonym: "up regulation of metalloprotease activity" NARROW [GOC:TermGenie] synonym: "up regulation of metalloproteinase activity" NARROW [GOC:TermGenie] synonym: "up-regulation of metallopeptidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of metalloprotease activity" NARROW [GOC:TermGenie] synonym: "up-regulation of metalloproteinase activity" NARROW [GOC:TermGenie] synonym: "upregulation of metallopeptidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of metalloprotease activity" NARROW [GOC:TermGenie] synonym: "upregulation of metalloproteinase activity" NARROW [GOC:TermGenie] is_a: GO:0010952 ! positive regulation of peptidase activity is_a: GO:1905048 ! regulation of metallopeptidase activity created_by: mm2 creation_date: 2016-03-15T16:44:46Z [Term] id: GO:1905097 name: regulation of guanyl-nucleotide exchange factor activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of guanyl-nucleotide exchange factor activity." [GO_REF:0000059, GOC:TermGenie, PMID:20484009] subset: gocheck_obsoletion_candidate synonym: "regulation of GDP-dissociation stimulator activity" EXACT [GOC:TermGenie] synonym: "regulation of GDS" EXACT [GOC:TermGenie] synonym: "regulation of GEF" EXACT [GOC:TermGenie] synonym: "regulation of GNRP" NARROW [GOC:TermGenie] synonym: "regulation of guanyl-nucleotide release factor activity" EXACT [GOC:TermGenie] synonym: "regulation of guanyl-nucleotide releasing factor" EXACT [GOC:TermGenie] is_a: GO:0051336 ! regulation of hydrolase activity property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18750" xsd:anyURI created_by: sl creation_date: 2016-03-31T16:09:35Z [Term] id: GO:1905098 name: negative regulation of guanyl-nucleotide exchange factor activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of guanyl-nucleotide exchange factor activity." [GO_REF:0000059, GOC:TermGenie, PMID:20484009] subset: gocheck_obsoletion_candidate synonym: "down regulation of GDP-dissociation stimulator activity" EXACT [GOC:TermGenie] synonym: "down regulation of GDS" EXACT [GOC:TermGenie] synonym: "down regulation of GEF" EXACT [GOC:TermGenie] synonym: "down regulation of GNRP" NARROW [GOC:TermGenie] synonym: "down regulation of guanyl-nucleotide exchange factor activity" EXACT [GOC:TermGenie] synonym: "down regulation of guanyl-nucleotide release factor activity" EXACT [GOC:TermGenie] synonym: "down regulation of guanyl-nucleotide releasing factor" EXACT [GOC:TermGenie] synonym: "down-regulation of GDP-dissociation stimulator activity" EXACT [GOC:TermGenie] synonym: "down-regulation of GDS" EXACT [GOC:TermGenie] synonym: "down-regulation of GEF" EXACT [GOC:TermGenie] synonym: "down-regulation of GNRP" NARROW [GOC:TermGenie] synonym: "down-regulation of guanyl-nucleotide exchange factor activity" EXACT [GOC:TermGenie] synonym: "down-regulation of guanyl-nucleotide release factor activity" EXACT [GOC:TermGenie] synonym: "down-regulation of guanyl-nucleotide releasing factor" EXACT [GOC:TermGenie] synonym: "downregulation of GDP-dissociation stimulator activity" EXACT [GOC:TermGenie] synonym: "downregulation of GDS" EXACT [GOC:TermGenie] synonym: "downregulation of GEF" EXACT [GOC:TermGenie] synonym: "downregulation of GNRP" NARROW [GOC:TermGenie] synonym: "downregulation of guanyl-nucleotide exchange factor activity" EXACT [GOC:TermGenie] synonym: "downregulation of guanyl-nucleotide release factor activity" EXACT [GOC:TermGenie] synonym: "downregulation of guanyl-nucleotide releasing factor" EXACT [GOC:TermGenie] synonym: "inhibition of GDP-dissociation stimulator activity" NARROW [GOC:TermGenie] synonym: "inhibition of GDS" NARROW [GOC:TermGenie] synonym: "inhibition of GEF" NARROW [GOC:TermGenie] synonym: "inhibition of GNRP" NARROW [GOC:TermGenie] synonym: "inhibition of guanyl-nucleotide exchange factor activity" NARROW [GOC:TermGenie] synonym: "inhibition of guanyl-nucleotide release factor activity" NARROW [GOC:TermGenie] synonym: "inhibition of guanyl-nucleotide releasing factor" NARROW [GOC:TermGenie] synonym: "negative regulation of GDP-dissociation stimulator activity" EXACT [GOC:TermGenie] synonym: "negative regulation of GDS" EXACT [GOC:TermGenie] synonym: "negative regulation of GEF" EXACT [GOC:TermGenie] synonym: "negative regulation of GNRP" NARROW [GOC:TermGenie] synonym: "negative regulation of guanyl-nucleotide release factor activity" EXACT [GOC:TermGenie] synonym: "negative regulation of guanyl-nucleotide releasing factor" EXACT [GOC:TermGenie] is_a: GO:0044093 ! positive regulation of molecular function is_a: GO:1905097 ! regulation of guanyl-nucleotide exchange factor activity property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18750" xsd:anyURI created_by: sl creation_date: 2016-03-31T16:09:45Z [Term] id: GO:1905099 name: positive regulation of guanyl-nucleotide exchange factor activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of guanyl-nucleotide exchange factor activity." [GO_REF:0000059, GOC:TermGenie, PMID:20484009] subset: gocheck_obsoletion_candidate synonym: "activation of GDP-dissociation stimulator activity" NARROW [GOC:TermGenie] synonym: "activation of GDS" NARROW [GOC:TermGenie] synonym: "activation of GEF" NARROW [GOC:TermGenie] synonym: "activation of GNRP" NARROW [GOC:TermGenie] synonym: "activation of guanyl-nucleotide exchange factor activity" NARROW [GOC:TermGenie] synonym: "activation of guanyl-nucleotide release factor activity" NARROW [GOC:TermGenie] synonym: "activation of guanyl-nucleotide releasing factor" NARROW [GOC:TermGenie] synonym: "positive regulation of GDP-dissociation stimulator activity" EXACT [GOC:TermGenie] synonym: "positive regulation of GDS" EXACT [GOC:TermGenie] synonym: "positive regulation of GEF" EXACT [GOC:TermGenie] synonym: "positive regulation of GNRP" NARROW [GOC:TermGenie] synonym: "positive regulation of guanyl-nucleotide release factor activity" EXACT [GOC:TermGenie] synonym: "positive regulation of guanyl-nucleotide releasing factor" EXACT [GOC:TermGenie] synonym: "up regulation of GDP-dissociation stimulator activity" EXACT [GOC:TermGenie] synonym: "up regulation of GDS" EXACT [GOC:TermGenie] synonym: "up regulation of GEF" EXACT [GOC:TermGenie] synonym: "up regulation of GNRP" NARROW [GOC:TermGenie] synonym: "up regulation of guanyl-nucleotide exchange factor activity" EXACT [GOC:TermGenie] synonym: "up regulation of guanyl-nucleotide release factor activity" EXACT [GOC:TermGenie] synonym: "up regulation of guanyl-nucleotide releasing factor" EXACT [GOC:TermGenie] synonym: "up-regulation of GDP-dissociation stimulator activity" EXACT [GOC:TermGenie] synonym: "up-regulation of GDS" EXACT [GOC:TermGenie] synonym: "up-regulation of GEF" EXACT [GOC:TermGenie] synonym: "up-regulation of GNRP" NARROW [GOC:TermGenie] synonym: "up-regulation of guanyl-nucleotide exchange factor activity" EXACT [GOC:TermGenie] synonym: "up-regulation of guanyl-nucleotide release factor activity" EXACT [GOC:TermGenie] synonym: "up-regulation of guanyl-nucleotide releasing factor" EXACT [GOC:TermGenie] synonym: "upregulation of GDP-dissociation stimulator activity" EXACT [GOC:TermGenie] synonym: "upregulation of GDS" EXACT [GOC:TermGenie] synonym: "upregulation of GEF" EXACT [GOC:TermGenie] synonym: "upregulation of GNRP" NARROW [GOC:TermGenie] synonym: "upregulation of guanyl-nucleotide exchange factor activity" EXACT [GOC:TermGenie] synonym: "upregulation of guanyl-nucleotide release factor activity" EXACT [GOC:TermGenie] synonym: "upregulation of guanyl-nucleotide releasing factor" EXACT [GOC:TermGenie] is_a: GO:0044093 ! positive regulation of molecular function is_a: GO:1905097 ! regulation of guanyl-nucleotide exchange factor activity property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18750" xsd:anyURI created_by: sl creation_date: 2016-03-31T16:09:54Z [Term] id: GO:1905118 name: positive regulation of ribonucleoside-diphosphate reductase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of ribonucleoside-diphosphate reductase activity." [GO_REF:0000059, GOC:bhm, GOC:TermGenie, PMID:24733891] comment: An example of this is DRE2 in Saccharomyces cerevisiae (UniProt ID P36152) in PMID:24733891 (inferred from mutant phenotype). subset: gocheck_obsoletion_candidate synonym: "activation of adenosylcobalamin-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "activation of aerobic non-heme iron-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "activation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "activation of class I ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "activation of class II ribonucleoside-diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "activation of class II ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "activation of class III ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "activation of nucleoside diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "activation of purine/pyrimidine nucleoside diphosphate reduction" RELATED [GOC:TermGenie] synonym: "activation of ribonucleoside 5'-diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "activation of ribonucleoside-diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "activation of ribonucleotide diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "activation of RNR" RELATED [GOC:TermGenie] synonym: "positive regulation of adenosylcobalamin-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "positive regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "positive regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "positive regulation of class I ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "positive regulation of class II ribonucleoside-diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "positive regulation of class II ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "positive regulation of class III ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "positive regulation of nucleoside diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "positive regulation of purine/pyrimidine nucleoside diphosphate reduction" RELATED [GOC:TermGenie] synonym: "positive regulation of ribonucleoside 5'-diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "positive regulation of ribonucleotide diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "positive regulation of RNR" RELATED [GOC:TermGenie] synonym: "up regulation of adenosylcobalamin-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "up regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "up regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "up regulation of class I ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "up regulation of class II ribonucleoside-diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "up regulation of class II ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "up regulation of class III ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "up regulation of nucleoside diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "up regulation of purine/pyrimidine nucleoside diphosphate reduction" RELATED [GOC:TermGenie] synonym: "up regulation of ribonucleoside 5'-diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "up regulation of ribonucleoside-diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "up regulation of ribonucleotide diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "up regulation of RNR" RELATED [GOC:TermGenie] synonym: "up-regulation of adenosylcobalamin-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "up-regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "up-regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "up-regulation of class I ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "up-regulation of class II ribonucleoside-diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "up-regulation of class II ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "up-regulation of class III ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "up-regulation of nucleoside diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "up-regulation of purine/pyrimidine nucleoside diphosphate reduction" RELATED [GOC:TermGenie] synonym: "up-regulation of ribonucleoside 5'-diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "up-regulation of ribonucleoside-diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "up-regulation of ribonucleotide diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "up-regulation of RNR" RELATED [GOC:TermGenie] synonym: "upregulation of adenosylcobalamin-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "upregulation of aerobic non-heme iron-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "upregulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "upregulation of class I ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "upregulation of class II ribonucleoside-diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "upregulation of class II ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "upregulation of class III ribonucleotide reductase activity" RELATED [GOC:TermGenie] synonym: "upregulation of nucleoside diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "upregulation of purine/pyrimidine nucleoside diphosphate reduction" RELATED [GOC:TermGenie] synonym: "upregulation of ribonucleoside 5'-diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "upregulation of ribonucleoside-diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "upregulation of ribonucleotide diphosphate reductase activity" RELATED [GOC:TermGenie] synonym: "upregulation of RNR" RELATED [GOC:TermGenie] is_a: GO:0051353 ! positive regulation of oxidoreductase activity created_by: bhm creation_date: 2016-04-08T08:06:35Z [Term] id: GO:1905123 name: regulation of glucosylceramidase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glucosylceramidase activity." [GO_REF:0000059, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24334770] subset: gocheck_obsoletion_candidate synonym: "regulation of acid beta-glucosidase activity" EXACT [GOC:TermGenie] synonym: "regulation of beta-D-glucocerebrosidase activity" EXACT [GOC:TermGenie] synonym: "regulation of beta-glucocerebrosidase activity" EXACT [GOC:TermGenie] synonym: "regulation of beta-glucosylceramidase activity" EXACT [GOC:TermGenie] synonym: "regulation of ceramide glucosidase activity" EXACT [GOC:TermGenie] synonym: "regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity" EXACT [GOC:TermGenie] synonym: "regulation of GCase activity" EXACT [PMID:24334770] synonym: "regulation of GlcCer-beta-glucosidase activity" EXACT [GOC:TermGenie] synonym: "regulation of glucocerebrosidase activity" EXACT [GOC:TermGenie] synonym: "regulation of glucosphingosine glucosylhydrolase activity" EXACT [GOC:TermGenie] synonym: "regulation of glucosylcerebrosidase activity" EXACT [GOC:TermGenie] synonym: "regulation of glucosylsphingosine beta-D-glucosidase activity" EXACT [GOC:TermGenie] synonym: "regulation of glucosylsphingosine beta-glucosidase activity" EXACT [GOC:TermGenie] synonym: "regulation of psychosine hydrolase activity" EXACT [GOC:TermGenie] is_a: GO:0051336 ! regulation of hydrolase activity created_by: bf creation_date: 2016-04-11T15:44:26Z [Term] id: GO:1905150 name: regulation of voltage-gated sodium channel activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of voltage-gated sodium channel activity." [GO_REF:0000059, GOC:TermGenie, PMID:24198377] subset: gocheck_obsoletion_candidate synonym: "regulation of voltage gated sodium channel activity" EXACT [GOC:TermGenie] synonym: "regulation of voltage-dependent sodium channel activity" EXACT [GOC:TermGenie] synonym: "regulation of voltage-gated sodium ion channel activity" EXACT [GOC:TermGenie] synonym: "regulation of voltage-sensitive sodium channel" EXACT [GOC:TermGenie] is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity is_a: GO:2001257 ! regulation of cation channel activity created_by: sl creation_date: 2016-04-15T21:47:40Z [Term] id: GO:1905151 name: negative regulation of voltage-gated sodium channel activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated sodium channel activity." [GO_REF:0000059, GOC:TermGenie, PMID:24198377] subset: gocheck_obsoletion_candidate synonym: "down regulation of voltage gated sodium channel activity" EXACT [GOC:TermGenie] synonym: "down regulation of voltage-dependent sodium channel activity" EXACT [GOC:TermGenie] synonym: "down regulation of voltage-gated sodium channel activity" EXACT [GOC:TermGenie] synonym: "down regulation of voltage-gated sodium ion channel activity" EXACT [GOC:TermGenie] synonym: "down regulation of voltage-sensitive sodium channel" EXACT [GOC:TermGenie] synonym: "down-regulation of voltage gated sodium channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of voltage-dependent sodium channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of voltage-gated sodium channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of voltage-gated sodium ion channel activity" EXACT [GOC:TermGenie] synonym: "down-regulation of voltage-sensitive sodium channel" EXACT [GOC:TermGenie] synonym: "downregulation of voltage gated sodium channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of voltage-dependent sodium channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of voltage-gated sodium channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of voltage-gated sodium ion channel activity" EXACT [GOC:TermGenie] synonym: "downregulation of voltage-sensitive sodium channel" EXACT [GOC:TermGenie] synonym: "inhibition of voltage gated sodium channel activity" NARROW [GOC:TermGenie] synonym: "inhibition of voltage-dependent sodium channel activity" NARROW [GOC:TermGenie] synonym: "inhibition of voltage-gated sodium channel activity" NARROW [GOC:TermGenie] synonym: "inhibition of voltage-gated sodium ion channel activity" NARROW [GOC:TermGenie] synonym: "inhibition of voltage-sensitive sodium channel" NARROW [GOC:TermGenie] synonym: "negative regulation of voltage gated sodium channel activity" EXACT [GOC:TermGenie] synonym: "negative regulation of voltage-dependent sodium channel activity" EXACT [GOC:TermGenie] synonym: "negative regulation of voltage-gated sodium ion channel activity" EXACT [GOC:TermGenie] synonym: "negative regulation of voltage-sensitive sodium channel" EXACT [GOC:TermGenie] is_a: GO:1905150 ! regulation of voltage-gated sodium channel activity is_a: GO:2000650 ! negative regulation of sodium ion transmembrane transporter activity is_a: GO:2001258 ! negative regulation of cation channel activity created_by: sl creation_date: 2016-04-15T21:47:49Z [Term] id: GO:1905152 name: positive regulation of voltage-gated sodium channel activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of voltage-gated sodium channel activity." [GO_REF:0000059, GOC:TermGenie, PMID:24198377] subset: gocheck_obsoletion_candidate synonym: "activation of voltage gated sodium channel activity" NARROW [GOC:TermGenie] synonym: "activation of voltage-dependent sodium channel activity" NARROW [GOC:TermGenie] synonym: "activation of voltage-gated sodium channel activity" NARROW [GOC:TermGenie] synonym: "activation of voltage-gated sodium ion channel activity" NARROW [GOC:TermGenie] synonym: "activation of voltage-sensitive sodium channel" NARROW [GOC:TermGenie] synonym: "positive regulation of voltage gated sodium channel activity" EXACT [GOC:TermGenie] synonym: "positive regulation of voltage-dependent sodium channel activity" EXACT [GOC:TermGenie] synonym: "positive regulation of voltage-gated sodium ion channel activity" EXACT [GOC:TermGenie] synonym: "positive regulation of voltage-sensitive sodium channel" EXACT [GOC:TermGenie] synonym: "up regulation of voltage gated sodium channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of voltage-dependent sodium channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of voltage-gated sodium channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of voltage-gated sodium ion channel activity" EXACT [GOC:TermGenie] synonym: "up regulation of voltage-sensitive sodium channel" EXACT [GOC:TermGenie] synonym: "up-regulation of voltage gated sodium channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of voltage-dependent sodium channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of voltage-gated sodium channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of voltage-gated sodium ion channel activity" EXACT [GOC:TermGenie] synonym: "up-regulation of voltage-sensitive sodium channel" EXACT [GOC:TermGenie] synonym: "upregulation of voltage gated sodium channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of voltage-dependent sodium channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of voltage-gated sodium channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of voltage-gated sodium ion channel activity" EXACT [GOC:TermGenie] synonym: "upregulation of voltage-sensitive sodium channel" EXACT [GOC:TermGenie] is_a: GO:1905150 ! regulation of voltage-gated sodium channel activity is_a: GO:2000651 ! positive regulation of sodium ion transmembrane transporter activity is_a: GO:2001259 ! positive regulation of cation channel activity created_by: sl creation_date: 2016-04-15T21:47:57Z [Term] id: GO:1905247 name: positive regulation of aspartic-type peptidase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of aspartic-type peptidase activity." [GO_REF:0000059, GOC:jl, GOC:TermGenie, PMID:21745575] subset: gocheck_obsoletion_candidate synonym: "activation of aspartic-type peptidase activity" NARROW [GOC:TermGenie] synonym: "up regulation of aspartic-type peptidase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of aspartic-type peptidase activity" EXACT [GOC:TermGenie] synonym: "upregulation of aspartic-type peptidase activity" EXACT [GOC:TermGenie] is_a: GO:0010952 ! positive regulation of peptidase activity created_by: jl creation_date: 2016-06-09T11:55:55Z [Term] id: GO:1905273 name: positive regulation of proton-transporting ATP synthase activity, rotational mechanism namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism." [GO_REF:0000059, GOC:als, GOC:TermGenie, PMID:21106936] subset: gocheck_obsoletion_candidate synonym: "activation of H+-transporting ATP synthase activity" NARROW [GOC:TermGenie] synonym: "activation of hydrogen ion translocating F-type ATPase activity" NARROW [GOC:TermGenie] synonym: "activation of hydrogen ion transporting ATP synthase activity, rotational mechanism" NARROW [GOC:TermGenie] synonym: "activation of hydrogen ion transporting two-sector ATPase activity" NARROW [GOC:TermGenie] synonym: "activation of proton-transporting ATP synthase activity, rotational mechanism" NARROW [GOC:TermGenie] synonym: "positive regulation of H+-transporting ATP synthase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of hydrogen ion translocating F-type ATPase activity" EXACT [GOC:TermGenie] synonym: "positive regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] synonym: "positive regulation of hydrogen ion transporting two-sector ATPase activity" EXACT [GOC:TermGenie] synonym: "up regulation of H+-transporting ATP synthase activity" EXACT [GOC:TermGenie] synonym: "up regulation of hydrogen ion translocating F-type ATPase activity" EXACT [GOC:TermGenie] synonym: "up regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] synonym: "up regulation of hydrogen ion transporting two-sector ATPase activity" EXACT [GOC:TermGenie] synonym: "up regulation of proton-transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] synonym: "up-regulation of H+-transporting ATP synthase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of hydrogen ion translocating F-type ATPase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] synonym: "up-regulation of hydrogen ion transporting two-sector ATPase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of proton-transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] synonym: "upregulation of H+-transporting ATP synthase activity" EXACT [GOC:TermGenie] synonym: "upregulation of hydrogen ion translocating F-type ATPase activity" EXACT [GOC:TermGenie] synonym: "upregulation of hydrogen ion transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] synonym: "upregulation of hydrogen ion transporting two-sector ATPase activity" EXACT [GOC:TermGenie] synonym: "upregulation of proton-transporting ATP synthase activity, rotational mechanism" EXACT [GOC:TermGenie] is_a: GO:0051351 ! positive regulation of ligase activity is_a: GO:2001259 ! positive regulation of cation channel activity created_by: als creation_date: 2016-06-16T12:10:05Z [Term] id: GO:1905408 name: negative regulation of creatine transmembrane transporter activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of creatine transmembrane transporter activity." [GO_REF:0000059, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25531585] subset: gocheck_obsoletion_candidate synonym: "down regulation of creatine transmembrane transporter activity" EXACT [GOC:TermGenie] synonym: "down-regulation of creatine transmembrane transporter activity" EXACT [GOC:TermGenie] synonym: "downregulation of creatine transmembrane transporter activity" EXACT [GOC:TermGenie] synonym: "inhibition of creatine transmembrane transporter activity" NARROW [GOC:TermGenie] is_a: GO:0022898 ! regulation of transmembrane transporter activity is_a: GO:0032410 ! negative regulation of transporter activity created_by: bc creation_date: 2016-08-25T15:08:56Z [Term] id: GO:1905598 name: negative regulation of low-density lipoprotein receptor activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein receptor activity." [GO_REF:0000059, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:22848640] subset: gocheck_obsoletion_candidate synonym: "down regulation of LDL receptor" EXACT [GOC:TermGenie] synonym: "down regulation of LDLR activity" EXACT [GOC:TermGenie] synonym: "down regulation of low-density lipoprotein receptor activity" EXACT [GOC:TermGenie] synonym: "down-regulation of LDL receptor" EXACT [GOC:TermGenie] synonym: "down-regulation of LDLR activity" EXACT [GOC:TermGenie] synonym: "down-regulation of low-density lipoprotein receptor activity" EXACT [GOC:TermGenie] synonym: "downregulation of LDL receptor" EXACT [GOC:TermGenie] synonym: "downregulation of LDLR activity" EXACT [GOC:TermGenie] synonym: "downregulation of low-density lipoprotein receptor activity" EXACT [GOC:TermGenie] synonym: "inhibition of LDL receptor" NARROW [GOC:TermGenie] synonym: "inhibition of LDLR activity" NARROW [GOC:TermGenie] synonym: "inhibition of low-density lipoprotein receptor activity" NARROW [GOC:TermGenie] synonym: "negative regulation of LDL receptor" EXACT [GOC:TermGenie] synonym: "negative regulation of LDLR activity" EXACT [GOC:TermGenie] is_a: GO:0065009 ! regulation of molecular function created_by: nc creation_date: 2016-10-26T11:53:34Z [Term] id: GO:1905599 name: positive regulation of low-density lipoprotein receptor activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of low-density lipoprotein receptor activity." [GO_REF:0000059, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:22848640] subset: gocheck_obsoletion_candidate synonym: "activation of LDL receptor" NARROW [GOC:TermGenie] synonym: "activation of LDLR activity" NARROW [GOC:TermGenie] synonym: "activation of low-density lipoprotein receptor activity" NARROW [GOC:TermGenie] synonym: "positive regulation of LDL receptor" EXACT [GOC:TermGenie] synonym: "positive regulation of LDLR activity" EXACT [GOC:TermGenie] synonym: "up regulation of LDL receptor" EXACT [GOC:TermGenie] synonym: "up regulation of LDLR activity" EXACT [GOC:TermGenie] synonym: "up regulation of low-density lipoprotein receptor activity" EXACT [GOC:TermGenie] synonym: "up-regulation of LDL receptor" EXACT [GOC:TermGenie] synonym: "up-regulation of LDLR activity" EXACT [GOC:TermGenie] synonym: "up-regulation of low-density lipoprotein receptor activity" EXACT [GOC:TermGenie] synonym: "upregulation of LDL receptor" EXACT [GOC:TermGenie] synonym: "upregulation of LDLR activity" EXACT [GOC:TermGenie] synonym: "upregulation of low-density lipoprotein receptor activity" EXACT [GOC:TermGenie] is_a: GO:0044093 ! positive regulation of molecular function created_by: nc creation_date: 2016-10-26T11:53:41Z [Term] id: GO:1905619 name: regulation of alpha-(1->3)-fucosyltransferase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity." [GO_REF:0000059, GOC:TermGenie, PMID:15364955] subset: gocheck_obsoletion_candidate synonym: "regulation of alpha(1,3)-fucosyltransferase activity" EXACT [GOC:TermGenie] synonym: "regulation of alpha-(1,3)-fucosyltransferase activity" EXACT [GOC:TermGenie] synonym: "regulation of alpha-1,3-fucosyltransferase activity" EXACT [GOC:TermGenie] is_a: GO:0051338 ! regulation of transferase activity created_by: rz creation_date: 2016-10-28T14:39:37Z [Term] id: GO:1905778 name: negative regulation of exonuclease activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of exonuclease activity." [GO_REF:0000059, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:15200954] subset: gocheck_obsoletion_candidate synonym: "down regulation of exonuclease activity" EXACT [GOC:TermGenie] synonym: "down regulation of exonuclease IX activity" NARROW [GOC:TermGenie] synonym: "down-regulation of exonuclease activity" EXACT [GOC:TermGenie] synonym: "down-regulation of exonuclease IX activity" NARROW [GOC:TermGenie] synonym: "downregulation of exonuclease activity" EXACT [GOC:TermGenie] synonym: "downregulation of exonuclease IX activity" NARROW [GOC:TermGenie] synonym: "inhibition of exonuclease activity" NARROW [GOC:TermGenie] synonym: "inhibition of exonuclease IX activity" NARROW [GOC:TermGenie] synonym: "negative regulation of exonuclease IX activity" NARROW [GOC:TermGenie] is_a: GO:0032074 ! negative regulation of nuclease activity created_by: nc creation_date: 2016-12-21T21:32:16Z [Term] id: GO:1905919 name: negative regulation of CoA-transferase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of CoA-transferase activity." [GO_REF:0000059, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328] subset: gocheck_obsoletion_candidate synonym: "down regulation of CoA-transferase activity" EXACT [GOC:TermGenie] synonym: "down-regulation of CoA-transferase activity" EXACT [GOC:TermGenie] synonym: "downregulation of CoA-transferase activity" EXACT [GOC:TermGenie] synonym: "inhibition of CoA-transferase activity" NARROW [GOC:TermGenie] is_a: GO:0051348 ! negative regulation of transferase activity created_by: bc creation_date: 2017-02-08T13:00:56Z [Term] id: GO:1905920 name: positive regulation of CoA-transferase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of CoA-transferase activity." [GO_REF:0000059, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328] subset: gocheck_obsoletion_candidate synonym: "activation of CoA-transferase activity" NARROW [GOC:TermGenie] synonym: "up regulation of CoA-transferase activity" EXACT [GOC:TermGenie] synonym: "up-regulation of CoA-transferase activity" EXACT [GOC:TermGenie] synonym: "upregulation of CoA-transferase activity" EXACT [GOC:TermGenie] is_a: GO:0051347 ! positive regulation of transferase activity created_by: bc creation_date: 2017-02-08T13:01:04Z [Term] id: GO:1990051 name: activation of protein kinase C activity namespace: biological_process def: "Any process that initiates the activity of the inactive enzyme protein kinase C." [PMID:3156004] subset: gocheck_obsoletion_candidate synonym: "PKC activation" EXACT [] synonym: "protein kinase C activation" EXACT [] is_a: GO:0032147 ! activation of protein kinase activity created_by: sl creation_date: 2013-02-21T19:57:54Z [Term] id: GO:1990264 name: peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity namespace: biological_process def: "Any peptidyl-tyrosine dephosphorylation that is involved in inactivation of protein kinase activity." [PMID:7501024] subset: gocheck_obsoletion_candidate is_a: GO:0035335 ! peptidyl-tyrosine dephosphorylation relationship: part_of GO:0006469 ! negative regulation of protein kinase activity created_by: al creation_date: 2014-01-09T14:28:41Z [Term] id: GO:1990443 name: peptidyl-threonine autophosphorylation namespace: biological_process def: "The phosphorylation by a protein of one or more of its own threonine amino acid residues, or a threonine residue on an identical protein." [PMID:7803855] subset: gocheck_obsoletion_candidate is_a: GO:0018107 ! peptidyl-threonine phosphorylation is_a: GO:0046777 ! protein autophosphorylation created_by: al creation_date: 2014-08-02T15:08:41Z [Term] id: GO:1990577 name: C-terminal protein demethylation namespace: biological_process def: "The removal of a methyl group from the C-terminal amino acid of a protein." [PMID:11060018] subset: gocheck_obsoletion_candidate is_a: GO:0006482 ! protein demethylation created_by: mcc creation_date: 2014-12-08T20:55:17Z [Term] id: GO:1990579 name: peptidyl-serine trans-autophosphorylation namespace: biological_process def: "The phosphorylation of a peptidyl-serine to form peptidyl-O-phospho-L-serine on an identical protein. For example, phosphorylation by the other kinase within a homodimer." [GOC:bf, GOC:PARL, PMID:21317875] subset: gocheck_obsoletion_candidate synonym: "serine autophosphorylation in trans" EXACT [PMID:21317875] synonym: "serine transautophosphorylation" EXACT [PMID:21317875] is_a: GO:0036289 ! peptidyl-serine autophosphorylation is_a: GO:0036290 ! protein trans-autophosphorylation created_by: bf creation_date: 2014-12-09T09:20:08Z [Term] id: GO:1990697 name: protein depalmitoleylation namespace: biological_process def: "The removal of palmitoleyl group, a 16-carbon monounsaturated fatty acid (C16:1), from a lipoprotein." [PMID:25731175] subset: gocheck_obsoletion_candidate is_a: GO:0035601 ! protein deacylation created_by: sp creation_date: 2015-03-13T08:55:31Z [Term] id: GO:1990743 name: protein sialylation namespace: biological_process def: "A protein modification process that results in the addition of a sialic acid unit to the end of an oligosaccharide chain in a glycoprotein." [PMID:21930713] subset: gocheck_obsoletion_candidate is_a: GO:0043412 ! macromolecule modification created_by: sl creation_date: 2015-05-14T20:18:28Z [Term] id: GO:1990787 name: negative regulation of hh target transcription factor activity namespace: biological_process def: "Any process that decreases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates members of the Gli protein family are activated by Hedgehog signaling." [GOC:bhm, PMID:24311597] subset: gocheck_obsoletion_candidate synonym: "negative regulation of hedgehog target transcription factor" EXACT [] is_a: GO:0051090 ! regulation of DNA-binding transcription factor activity created_by: bhm creation_date: 2015-06-26T09:54:29Z [Term] id: GO:1990938 name: peptidyl-aspartic acid autophosphorylation namespace: biological_process def: "The phosphorylation by a protein of one or more of its own aspartate amino acid residues, or an aspartate residue on an identical protein." [GOC:bf, GOC:PARL, PMID:26134396] subset: gocheck_obsoletion_candidate synonym: "aspartyl autophosphorylation" EXACT [PMID:26134396] synonym: "peptidyl-aspartate autophosphorylation" EXACT [GOC:bf] is_a: GO:0018217 ! peptidyl-aspartic acid phosphorylation is_a: GO:0046777 ! protein autophosphorylation created_by: bf creation_date: 2016-04-04T10:49:53Z [Term] id: GO:2000152 name: regulation of ubiquitin-specific protease activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of regulation of ubiquitin-specific protease activity (deubiquitinase) activity." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "regulation of deubiquitinase activity" EXACT [] synonym: "regulation of UBP" RELATED [GOC:obol] synonym: "regulation of UCH2" RELATED [GOC:obol] is_a: GO:0052547 ! regulation of peptidase activity created_by: tb creation_date: 2010-10-01T10:09:28Z [Term] id: GO:2000157 name: negative regulation of ubiquitin-specific protease activity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "negative regulation of deubiquitinase activity" EXACT [] synonym: "negative regulation of ubiquitin hydrolase activity" EXACT [GOC:obol] synonym: "negative regulation of UBP" RELATED [GOC:obol] synonym: "negative regulation of UCH2" RELATED [GOC:obol] is_a: GO:0010466 ! negative regulation of peptidase activity is_a: GO:2000152 ! regulation of ubiquitin-specific protease activity created_by: tb creation_date: 2010-10-04T10:42:27Z [Term] id: GO:2000158 name: positive regulation of ubiquitin-specific protease activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "positive regulation of deubiquitinase activity" EXACT [] synonym: "positive regulation of ubiquitin hydrolase activity" EXACT [GOC:obol] synonym: "positive regulation of UBP" RELATED [GOC:obol] synonym: "positive regulation of UCH2" RELATED [GOC:obol] is_a: GO:0010952 ! positive regulation of peptidase activity is_a: GO:2000152 ! regulation of ubiquitin-specific protease activity created_by: tb creation_date: 2010-10-04T10:42:29Z [Term] id: GO:2000169 name: regulation of peptidyl-cysteine S-nitrosylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of peptidyl-cysteine S-nitrosylation." [GOC:obol] subset: gocheck_obsoletion_candidate relationship: regulates GO:0018119 ! peptidyl-cysteine S-nitrosylation created_by: rl creation_date: 2010-10-07T10:49:32Z [Term] id: GO:2000170 name: positive regulation of peptidyl-cysteine S-nitrosylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of peptidyl-cysteine S-nitrosylation." [GOC:obol] subset: gocheck_obsoletion_candidate is_a: GO:0031401 ! positive regulation of protein modification process is_a: GO:2000169 ! regulation of peptidyl-cysteine S-nitrosylation relationship: positively_regulates GO:0018119 ! peptidyl-cysteine S-nitrosylation created_by: rl creation_date: 2010-10-07T10:49:35Z [Term] id: GO:2000272 name: negative regulation of signaling receptor activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "negative regulation of receptor activity" BROAD [] synonym: "negative regulation of signalling receptor activity" EXACT [] is_a: GO:0010469 ! regulation of signaling receptor activity created_by: bf creation_date: 2010-12-02T09:28:47Z [Term] id: GO:2000273 name: positive regulation of signaling receptor activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of signaling receptor activity." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "positive regulation of signalling receptor activity" EXACT [] is_a: GO:0010469 ! regulation of signaling receptor activity is_a: GO:0044093 ! positive regulation of molecular function created_by: bf creation_date: 2010-12-02T09:28:50Z [Term] id: GO:2000276 name: negative regulation of oxidative phosphorylation uncoupler activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of oxidative phosphorylation uncoupler activity." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "negative regulation of mitochondrial uncoupling protein activity" RELATED [GOC:obol] synonym: "negative regulation of uncoupling protein activity" RELATED [GOC:obol] is_a: GO:0022898 ! regulation of transmembrane transporter activity is_a: GO:0032410 ! negative regulation of transporter activity created_by: mah creation_date: 2010-12-07T12:14:59Z [Term] id: GO:2000277 name: positive regulation of oxidative phosphorylation uncoupler activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation uncoupler activity." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "positive regulation of mitochondrial uncoupling protein activity" RELATED [GOC:obol] synonym: "positive regulation of uncoupling protein activity" RELATED [GOC:obol] is_a: GO:0022898 ! regulation of transmembrane transporter activity is_a: GO:0032411 ! positive regulation of transporter activity created_by: mah creation_date: 2010-12-07T12:15:02Z [Term] id: GO:2000298 name: regulation of Rho-dependent protein serine/threonine kinase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "regulation of Rho-associated protein kinase activity" EXACT [GOC:obol] synonym: "regulation of ROCK kinase activity" EXACT [GOC:obol] is_a: GO:0071900 ! regulation of protein serine/threonine kinase activity created_by: mah creation_date: 2010-12-23T11:44:50Z [Term] id: GO:2000299 name: negative regulation of Rho-dependent protein serine/threonine kinase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "negative regulation of Rho-associated protein kinase activity" EXACT [GOC:obol] synonym: "negative regulation of ROCK kinase activity" EXACT [GOC:obol] is_a: GO:0071901 ! negative regulation of protein serine/threonine kinase activity is_a: GO:2000298 ! regulation of Rho-dependent protein serine/threonine kinase activity created_by: mah creation_date: 2010-12-23T11:44:57Z [Term] id: GO:2000310 name: regulation of NMDA receptor activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity." [GOC:BHF] subset: gocheck_obsoletion_candidate synonym: "regulation of N-methyl-D-aspartate selective glutamate receptor activity" EXACT [] xref: Reactome:R-HSA-438066 "Unblocking of NMDA receptors, glutamate binding and activation" is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity is_a: GO:0099601 ! regulation of neurotransmitter receptor activity created_by: bf creation_date: 2011-01-18T10:06:37Z [Term] id: GO:2000311 name: regulation of AMPA receptor activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of AMPA selective glutamate receptor activity." [GOC:BHF] subset: gocheck_obsoletion_candidate synonym: "regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity" EXACT [] is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity is_a: GO:0099601 ! regulation of neurotransmitter receptor activity created_by: bf creation_date: 2011-01-18T10:10:28Z [Term] id: GO:2000312 name: regulation of kainate selective glutamate receptor activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of kainate selective glutamate receptor activity." [GOC:BHF] subset: gocheck_obsoletion_candidate is_a: GO:0099601 ! regulation of neurotransmitter receptor activity is_a: GO:1901016 ! regulation of potassium ion transmembrane transporter activity is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity is_a: GO:2001257 ! regulation of cation channel activity created_by: bf creation_date: 2011-01-18T10:14:16Z [Term] id: GO:2000363 name: positive regulation of prostaglandin-E synthase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of prostaglandin-E synthase activity." [GOC:BHF] subset: gocheck_obsoletion_candidate synonym: "positive regulation of (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity" EXACT [GOC:obol] synonym: "positive regulation of endoperoxide isomerase activity" EXACT [GOC:obol] synonym: "positive regulation of PGE isomerase activity" EXACT [GOC:obol] synonym: "positive regulation of PGE2 isomerase activity" EXACT [GOC:obol] synonym: "positive regulation of PGH-PGE isomerase activity" EXACT [GOC:obol] synonym: "positive regulation of prostaglandin endoperoxide E isomerase activity" EXACT [GOC:obol] synonym: "positive regulation of prostaglandin endoperoxide E2 isomerase activity" EXACT [GOC:obol] synonym: "positive regulation of prostaglandin H-E isomerase activity" EXACT [GOC:obol] synonym: "positive regulation of prostaglandin R-prostaglandin E isomerase activity" EXACT [GOC:obol] synonym: "positive regulation of Prostaglandin-H(2) E-isomerase activity" EXACT [GOC:obol] synonym: "positive regulation of prostaglandin-H2 E-isomerase activity" EXACT [GOC:obol] is_a: GO:0043085 ! positive regulation of catalytic activity created_by: bf creation_date: 2011-02-03T04:05:42Z [Term] id: GO:2000373 name: positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity." [GOC:mah] subset: gocheck_obsoletion_candidate synonym: "positive regulation of deoxyribonucleate topoisomerase" RELATED [GOC:obol] synonym: "positive regulation of deoxyribonucleic topoisomerase activity" EXACT [GOC:obol] synonym: "positive regulation of DNA topoisomerase (ATP-hydrolysing)" RELATED [GOC:obol] synonym: "positive regulation of DNA topoisomerase II" RELATED [GOC:obol] synonym: "positive regulation of DNA topoisomerase IV activity" EXACT [GOC:obol] synonym: "positive regulation of DNA topoisomerase type II activity" EXACT [GOC:obol] synonym: "positive regulation of topoisomerase" RELATED [GOC:obol] synonym: "positive regulation of topoisomerase II" EXACT [GOC:obol] synonym: "positive regulation of type II DNA topoisomerase activity" EXACT [GOC:obol] is_a: GO:0032781 ! positive regulation of ATP-dependent activity is_a: GO:0043085 ! positive regulation of catalytic activity created_by: mah creation_date: 2011-02-09T02:35:43Z [Term] id: GO:2000465 name: regulation of glycogen (starch) synthase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glycogen (starch) synthase activity." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "regulation of glycogen (starch) synthetase activity" EXACT [GOC:obol] synonym: "regulation of UDP-glucose-glycogen glucosyltransferase activity" EXACT [GOC:obol] synonym: "regulation of UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity" EXACT [GOC:obol] synonym: "regulation of UDP-glycogen synthase activity" EXACT [GOC:obol] synonym: "regulation of UDPG-glycogen synthetase activity" EXACT [GOC:obol] synonym: "regulation of UDPG-glycogen transglucosylase activity" EXACT [GOC:obol] synonym: "regulation of UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity" EXACT [GOC:obol] synonym: "regulation of uridine diphosphoglucose-glycogen glucosyltransferase activity" EXACT [GOC:obol] is_a: GO:0051338 ! regulation of transferase activity created_by: yaf creation_date: 2011-03-07T04:12:35Z [Term] id: GO:2000466 name: negative regulation of glycogen (starch) synthase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of glycogen (starch) synthase activity." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "negative regulation of glycogen (starch) synthetase activity" EXACT [GOC:obol] synonym: "negative regulation of UDP-glucose-glycogen glucosyltransferase activity" EXACT [GOC:obol] synonym: "negative regulation of UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity" EXACT [GOC:obol] synonym: "negative regulation of UDP-glycogen synthase activity" EXACT [GOC:obol] synonym: "negative regulation of UDPG-glycogen synthetase activity" EXACT [GOC:obol] synonym: "negative regulation of UDPG-glycogen transglucosylase activity" EXACT [GOC:obol] synonym: "negative regulation of UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity" EXACT [GOC:obol] synonym: "negative regulation of uridine diphosphoglucose-glycogen glucosyltransferase activity" EXACT [GOC:obol] is_a: GO:0051348 ! negative regulation of transferase activity is_a: GO:2000465 ! regulation of glycogen (starch) synthase activity created_by: yaf creation_date: 2011-03-07T04:13:14Z [Term] id: GO:2000467 name: positive regulation of glycogen (starch) synthase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of glycogen (starch) synthase activity." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "positive regulation of glycogen (starch) synthetase activity" EXACT [GOC:obol] synonym: "positive regulation of UDP-glucose-glycogen glucosyltransferase activity" EXACT [GOC:obol] synonym: "positive regulation of UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity" EXACT [GOC:obol] synonym: "positive regulation of UDP-glycogen synthase activity" EXACT [GOC:obol] synonym: "positive regulation of UDPG-glycogen synthetase activity" EXACT [GOC:obol] synonym: "positive regulation of UDPG-glycogen transglucosylase activity" EXACT [GOC:obol] synonym: "positive regulation of UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity" EXACT [GOC:obol] synonym: "positive regulation of uridine diphosphoglucose-glycogen glucosyltransferase activity" EXACT [GOC:obol] is_a: GO:0051347 ! positive regulation of transferase activity is_a: GO:2000465 ! regulation of glycogen (starch) synthase activity created_by: yaf creation_date: 2011-03-07T04:13:41Z [Term] id: GO:2000470 name: positive regulation of peroxidase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of peroxidase activity." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "positive regulation of donor:hydrogen-peroxide oxidoreductase activity" EXACT [GOC:obol] synonym: "positive regulation of oxyperoxidase activity" EXACT [GOC:obol] synonym: "positive regulation of peroxidase reaction" EXACT [GOC:obol] is_a: GO:0051353 ! positive regulation of oxidoreductase activity created_by: bf creation_date: 2011-03-08T02:19:25Z [Term] id: GO:2000479 name: regulation of cAMP-dependent protein kinase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cAMP-dependent protein kinase activity." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "regulation of 3',5' cAMP-dependent protein kinase activity" EXACT [GOC:obol] synonym: "regulation of 3',5'-cAMP-dependent protein kinase activity" EXACT [GOC:obol] synonym: "regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity" EXACT [GOC:obol] synonym: "regulation of AMPK" RELATED [GOC:obol] synonym: "regulation of ATP:protein phosphotransferase (cAMP-dependent) activity" EXACT [GOC:obol] synonym: "regulation of cAMP-dependent protein kinase, intrinsic catalyst activity" EXACT [GOC:obol] synonym: "regulation of cyclic AMP-dependent protein kinase activity" EXACT [GOC:obol] synonym: "regulation of PKA" RELATED [GOC:obol] synonym: "regulation of PKA C" RELATED [GOC:obol] synonym: "regulation of protein kinase A activity" RELATED [GOC:obol] synonym: "regulation of STK22" RELATED [GOC:obol] is_a: GO:0071900 ! regulation of protein serine/threonine kinase activity created_by: yaf creation_date: 2011-03-10T11:13:01Z [Term] id: GO:2000480 name: negative regulation of cAMP-dependent protein kinase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "negative regulation of 3',5' cAMP-dependent protein kinase activity" EXACT [GOC:obol] synonym: "negative regulation of 3',5'-cAMP-dependent protein kinase activity" EXACT [GOC:obol] synonym: "negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity" EXACT [GOC:obol] synonym: "negative regulation of AMPK" RELATED [GOC:obol] synonym: "negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity" EXACT [GOC:obol] synonym: "negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity" EXACT [GOC:obol] synonym: "negative regulation of cyclic AMP-dependent protein kinase activity" EXACT [GOC:obol] synonym: "negative regulation of PKA" RELATED [GOC:obol] synonym: "negative regulation of PKA C" RELATED [GOC:obol] synonym: "negative regulation of protein kinase A activity" RELATED [GOC:obol] synonym: "negative regulation of STK22" RELATED [GOC:obol] is_a: GO:0071901 ! negative regulation of protein serine/threonine kinase activity is_a: GO:2000479 ! regulation of cAMP-dependent protein kinase activity created_by: yaf creation_date: 2011-03-10T11:13:45Z [Term] id: GO:2000481 name: positive regulation of cAMP-dependent protein kinase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cAMP-dependent protein kinase activity." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "positive regulation of 3',5' cAMP-dependent protein kinase activity" EXACT [GOC:obol] synonym: "positive regulation of 3',5'-cAMP-dependent protein kinase activity" EXACT [GOC:obol] synonym: "positive regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity" EXACT [GOC:obol] synonym: "positive regulation of AMPK" RELATED [GOC:obol] synonym: "positive regulation of ATP:protein phosphotransferase (cAMP-dependent) activity" EXACT [GOC:obol] synonym: "positive regulation of cAMP-dependent protein kinase, intrinsic catalyst activity" EXACT [GOC:obol] synonym: "positive regulation of cyclic AMP-dependent protein kinase activity" EXACT [GOC:obol] synonym: "positive regulation of PKA" RELATED [GOC:obol] synonym: "positive regulation of PKA C" RELATED [GOC:obol] synonym: "positive regulation of protein kinase A activity" RELATED [GOC:obol] synonym: "positive regulation of STK22" RELATED [GOC:obol] is_a: GO:0071902 ! positive regulation of protein serine/threonine kinase activity is_a: GO:2000479 ! regulation of cAMP-dependent protein kinase activity created_by: yaf creation_date: 2011-03-10T11:14:17Z [Term] id: GO:2000539 name: regulation of protein geranylgeranylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein geranylgeranylation." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "regulation of C-terminal protein geranylgeranylation" RELATED [GOC:obol] synonym: "regulation of protein amino acid geranylgeranylation" EXACT [GOC:obol] relationship: regulates GO:0018344 ! protein geranylgeranylation created_by: tb creation_date: 2011-03-29T06:23:05Z [Term] id: GO:2000540 name: negative regulation of protein geranylgeranylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein geranylgeranylation." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "negative regulation of C-terminal protein geranylgeranylation" RELATED [GOC:obol] synonym: "negative regulation of protein amino acid geranylgeranylation" EXACT [GOC:obol] is_a: GO:0031400 ! negative regulation of protein modification process is_a: GO:2000539 ! regulation of protein geranylgeranylation relationship: negatively_regulates GO:0018344 ! protein geranylgeranylation created_by: tb creation_date: 2011-03-29T06:23:11Z [Term] id: GO:2000541 name: positive regulation of protein geranylgeranylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein geranylgeranylation." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "positive regulation of C-terminal protein geranylgeranylation" RELATED [GOC:obol] synonym: "positive regulation of protein amino acid geranylgeranylation" EXACT [GOC:obol] is_a: GO:0031401 ! positive regulation of protein modification process is_a: GO:2000539 ! regulation of protein geranylgeranylation relationship: positively_regulates GO:0018344 ! protein geranylgeranylation created_by: tb creation_date: 2011-03-29T06:23:15Z [Term] id: GO:2000649 name: regulation of sodium ion transmembrane transporter activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "regulation of sodium transporter activity" EXACT [GOC:obol] is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity created_by: yaf creation_date: 2011-04-28T08:42:53Z [Term] id: GO:2000650 name: negative regulation of sodium ion transmembrane transporter activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "negative regulation of sodium transporter activity" EXACT [GOC:obol] is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity created_by: yaf creation_date: 2011-04-28T08:42:57Z [Term] id: GO:2000651 name: positive regulation of sodium ion transmembrane transporter activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "positive regulation of sodium transporter activity" EXACT [GOC:obol] is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity created_by: yaf creation_date: 2011-04-28T08:43:00Z [Term] id: GO:2000756 name: regulation of peptidyl-lysine acetylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of peptidyl-lysine acetylation." [GOC:obol] subset: gocheck_obsoletion_candidate is_a: GO:1901983 ! regulation of protein acetylation relationship: regulates GO:0018394 ! peptidyl-lysine acetylation created_by: yaf creation_date: 2011-06-16T09:51:26Z [Term] id: GO:2000757 name: negative regulation of peptidyl-lysine acetylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-lysine acetylation." [GOC:obol] subset: gocheck_obsoletion_candidate is_a: GO:1901984 ! negative regulation of protein acetylation is_a: GO:2000756 ! regulation of peptidyl-lysine acetylation relationship: negatively_regulates GO:0018394 ! peptidyl-lysine acetylation created_by: yaf creation_date: 2011-06-16T09:51:31Z [Term] id: GO:2000758 name: positive regulation of peptidyl-lysine acetylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of peptidyl-lysine acetylation." [GOC:obol] subset: gocheck_obsoletion_candidate is_a: GO:1901985 ! positive regulation of protein acetylation is_a: GO:2000756 ! regulation of peptidyl-lysine acetylation relationship: positively_regulates GO:0018394 ! peptidyl-lysine acetylation created_by: yaf creation_date: 2011-06-16T09:51:35Z [Term] id: GO:2000759 name: regulation of N-terminal peptidyl-lysine acetylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of N-terminal peptidyl-lysine acetylation." [GOC:obol] subset: gocheck_obsoletion_candidate is_a: GO:2000756 ! regulation of peptidyl-lysine acetylation relationship: regulates GO:0018076 ! N-terminal peptidyl-lysine acetylation created_by: yaf creation_date: 2011-06-17T12:58:16Z [Term] id: GO:2000760 name: negative regulation of N-terminal peptidyl-lysine acetylation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-lysine acetylation." [GOC:obol] subset: gocheck_obsoletion_candidate is_a: GO:2000757 ! negative regulation of peptidyl-lysine acetylation is_a: GO:2000759 ! regulation of N-terminal peptidyl-lysine acetylation relationship: negatively_regulates GO:0018076 ! N-terminal peptidyl-lysine acetylation created_by: yaf creation_date: 2011-06-17T12:58:20Z [Term] id: GO:2000761 name: positive regulation of N-terminal peptidyl-lysine acetylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-lysine acetylation." [GOC:obol] subset: gocheck_obsoletion_candidate is_a: GO:2000758 ! positive regulation of peptidyl-lysine acetylation is_a: GO:2000759 ! regulation of N-terminal peptidyl-lysine acetylation relationship: positively_regulates GO:0018076 ! N-terminal peptidyl-lysine acetylation created_by: yaf creation_date: 2011-06-17T12:58:24Z [Term] id: GO:2000825 name: positive regulation of androgen receptor activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of androgen receptor activity." [GOC:obol] subset: gocheck_obsoletion_candidate is_a: GO:0051091 ! positive regulation of DNA-binding transcription factor activity is_a: GO:2000273 ! positive regulation of signaling receptor activity created_by: yaf creation_date: 2011-07-15T10:56:14Z [Term] id: GO:2000969 name: positive regulation of AMPA receptor activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of AMPA selective glutamate receptor activity." [PMID:21423165] subset: gocheck_obsoletion_candidate synonym: "positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity" BROAD [] is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity is_a: GO:2000273 ! positive regulation of signaling receptor activity is_a: GO:2000311 ! regulation of AMPA receptor activity created_by: pr creation_date: 2011-08-03T10:27:08Z [Term] id: GO:2000983 name: regulation of ATP citrate synthase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of ATP citrate synthase activity." [GOC:BHF] subset: gocheck_obsoletion_candidate synonym: "regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity" EXACT [GOC:obol] synonym: "regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)" EXACT [GOC:obol] synonym: "regulation of acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]" RELATED [GOC:obol] synonym: "regulation of adenosine triphosphate citrate lyase activity" EXACT [GOC:obol] synonym: "regulation of ATP citrate (pro-S)-lyase activity" EXACT [GOC:obol] synonym: "regulation of ATP-citrate (pro-S)-lyase activity" EXACT [GOC:obol] synonym: "regulation of ATP-citrate (pro-S-)-lyase activity" EXACT [GOC:obol] synonym: "regulation of ATP-citric lyase activity" EXACT [GOC:obol] synonym: "regulation of ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity" EXACT [GOC:obol] synonym: "regulation of ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)" RELATED [GOC:obol] synonym: "regulation of citrate cleavage enzyme activity" RELATED [GOC:obol] synonym: "regulation of citrate-ATP lyase activity" EXACT [GOC:obol] synonym: "regulation of citric cleavage enzyme activity" RELATED [GOC:obol] is_a: GO:0051338 ! regulation of transferase activity created_by: vk creation_date: 2011-08-04T03:15:24Z [Term] id: GO:2000984 name: negative regulation of ATP citrate synthase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of ATP citrate synthase activity." [GOC:BHF] subset: gocheck_obsoletion_candidate synonym: "negative regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity" EXACT [GOC:obol] synonym: "negative regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)" EXACT [GOC:obol] synonym: "negative regulation of acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]" RELATED [GOC:obol] synonym: "negative regulation of adenosine triphosphate citrate lyase activity" EXACT [GOC:obol] synonym: "negative regulation of ATP citrate (pro-S)-lyase activity" EXACT [GOC:obol] synonym: "negative regulation of ATP-citrate (pro-S)-lyase activity" EXACT [GOC:obol] synonym: "negative regulation of ATP-citrate (pro-S-)-lyase activity" EXACT [GOC:obol] synonym: "negative regulation of ATP-citric lyase activity" EXACT [GOC:obol] synonym: "negative regulation of ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity" EXACT [GOC:obol] synonym: "negative regulation of ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)" RELATED [GOC:obol] synonym: "negative regulation of citrate cleavage enzyme activity" RELATED [GOC:obol] synonym: "negative regulation of citrate-ATP lyase activity" EXACT [GOC:obol] synonym: "negative regulation of citric cleavage enzyme activity" RELATED [GOC:obol] is_a: GO:0051348 ! negative regulation of transferase activity is_a: GO:2000983 ! regulation of ATP citrate synthase activity created_by: vk creation_date: 2011-08-04T03:15:28Z [Term] id: GO:2000985 name: positive regulation of ATP citrate synthase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of ATP citrate synthase activity." [GOC:BHF] subset: gocheck_obsoletion_candidate synonym: "positive regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity" EXACT [GOC:obol] synonym: "positive regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)" EXACT [GOC:obol] synonym: "positive regulation of acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]" RELATED [GOC:obol] synonym: "positive regulation of adenosine triphosphate citrate lyase activity" EXACT [GOC:obol] synonym: "positive regulation of ATP citrate (pro-S)-lyase activity" EXACT [GOC:obol] synonym: "positive regulation of ATP-citrate (pro-S)-lyase activity" EXACT [GOC:obol] synonym: "positive regulation of ATP-citrate (pro-S-)-lyase activity" EXACT [GOC:obol] synonym: "positive regulation of ATP-citric lyase activity" EXACT [GOC:obol] synonym: "positive regulation of ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity" EXACT [GOC:obol] synonym: "positive regulation of ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)" RELATED [GOC:obol] synonym: "positive regulation of citrate cleavage enzyme activity" RELATED [GOC:obol] synonym: "positive regulation of citrate-ATP lyase activity" EXACT [GOC:obol] synonym: "positive regulation of citric cleavage enzyme activity" RELATED [GOC:obol] is_a: GO:0051347 ! positive regulation of transferase activity is_a: GO:2000983 ! regulation of ATP citrate synthase activity created_by: vk creation_date: 2011-08-04T03:15:31Z [Term] id: GO:2001106 name: regulation of Rho guanyl-nucleotide exchange factor activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "regulation of Rho guanine nucleotide exchange factor" EXACT [GOC:obol] synonym: "regulation of RhoGEF" EXACT [GOC:obol] is_a: GO:1905097 ! regulation of guanyl-nucleotide exchange factor activity created_by: yaf creation_date: 2011-09-23T10:13:06Z [Term] id: GO:2001107 name: negative regulation of Rho guanyl-nucleotide exchange factor activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "negative regulation of Rho guanine nucleotide exchange factor" EXACT [GOC:obol] synonym: "negative regulation of RhoGEF" EXACT [GOC:obol] is_a: GO:1905098 ! negative regulation of guanyl-nucleotide exchange factor activity created_by: yaf creation_date: 2011-09-23T10:13:12Z [Term] id: GO:2001108 name: positive regulation of Rho guanyl-nucleotide exchange factor activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity." [GOC:obol] subset: gocheck_obsoletion_candidate synonym: "positive regulation of Rho guanine nucleotide exchange factor" EXACT [GOC:obol] synonym: "positive regulation of RhoGEF" EXACT [GOC:obol] is_a: GO:1905099 ! positive regulation of guanyl-nucleotide exchange factor activity created_by: yaf creation_date: 2011-09-23T10:13:16Z [Term] id: GO:2001145 name: negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity." [GOC:obol] subset: gocheck_obsoletion_candidate is_a: GO:0010923 ! negative regulation of phosphatase activity created_by: yaf creation_date: 2011-10-19T10:41:28Z [Term] id: GO:2001257 name: regulation of cation channel activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cation channel activity." [GOC:BHF] subset: gocheck_obsoletion_candidate synonym: "regulation of cation diffusion facilitator activity" EXACT [GOC:obol] synonym: "regulation of nonselective cation channel activity" EXACT [GOC:obol] is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity created_by: vk creation_date: 2011-12-07T07:14:43Z [Term] id: GO:2001258 name: negative regulation of cation channel activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cation channel activity." [GOC:BHF] subset: gocheck_obsoletion_candidate synonym: "negative regulation of cation diffusion facilitator activity" EXACT [GOC:obol] synonym: "negative regulation of nonselective cation channel activity" EXACT [GOC:obol] is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity is_a: GO:2001257 ! regulation of cation channel activity created_by: vk creation_date: 2011-12-07T07:14:51Z [Term] id: GO:2001259 name: positive regulation of cation channel activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cation channel activity." [GOC:BHF] subset: gocheck_obsoletion_candidate synonym: "positive regulation of cation diffusion facilitator activity" EXACT [GOC:obol] synonym: "positive regulation of nonselective cation channel activity" EXACT [GOC:obol] is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity is_a: GO:2001257 ! regulation of cation channel activity created_by: vk creation_date: 2011-12-07T07:14:57Z [Typedef] id: ends_during name: ends during namespace: external xref: RO:0002093 [Typedef] id: happens_during name: happens during namespace: external xref: RO:0002092 is_transitive: true is_a: ends_during ! ends during [Typedef] id: has_ontology_root_term name: has ontology root term namespace: external xref: IAO:0000700 is_metadata_tag: true is_class_level: true [Typedef] id: has_part name: has part namespace: external xref: BFO:0000051 is_transitive: true [Typedef] id: negatively_regulates name: negatively regulates namespace: external xref: RO:0002212 is_a: regulates ! regulates [Typedef] id: occurs_in name: occurs in namespace: external xref: BFO:0000066 transitive_over: part_of ! part of [Typedef] id: part_of name: part of namespace: external xref: BFO:0000050 is_transitive: true inverse_of: has_part ! has part [Typedef] id: positively_regulates name: positively regulates namespace: external xref: RO:0002213 holds_over_chain: negatively_regulates negatively_regulates is_a: regulates ! regulates [Typedef] id: regulates name: regulates namespace: external xref: RO:0002211 is_transitive: true [Typedef] id: starts_during name: starts during namespace: external xref: RO:0002091 [Typedef] id: term_tracker_item name: term tracker item namespace: external xref: IAO:0000233 is_metadata_tag: true is_class_level: true