CHANGES IN GO ONTOLOGY

SUMMARY: CURRENT RELEASE
release_date	2024-12-18
valid_terms	40320
obsolete_terms	7649
merged_terms	2436
biological_process_terms	26135
molecular_function_terms	10157
cellular_component_terms	4028
meta_statements	274047
cross_references	24614
terms_relations	80105

SUMMARY: PREVIOUS RELEASE
release_date	2024-11-03
valid_terms	40635
obsolete_terms	7286
merged_terms	2436
biological_process_terms	26467
molecular_function_terms	10146
cellular_component_terms	4022
meta_statements	277271
cross_references	23657
terms_relations	81335

SUMMARY: DIFF BETWEEN RELEASES
changes_created_terms	48
changes_valid_terms	-315
changes_obsolete_terms	368
changes_merged_terms	0
changes_biological_process_terms	-332
changes_molecular_function_terms	11
changes_cellular_component_terms	6
changes_meta_statements	413
changes_meta_statements_by_term	255
changes_cross_references	1963
changes_cross_references_by_term	875
changes_relations	770
changes_relations_by_term	752

DETAILED CHANGES

48 CREATED TERMS
biological_process	GO:0014000	morula development
biological_process	GO:0120532	glycosaminoglycan-protein linkage region biosynthetic process
biological_process	GO:0120540	chondroitin sulfate proteoglycan biosynthetic process, enzymatic modification
biological_process	GO:0120541	dermatan sulfate proteoglycan biosynthetic process, enzymatic modification
biological_process	GO:0140001	morula formation
biological_process	GO:0160221	Rho-activating G protein-coupled receptor signaling pathway
biological_process	GO:0170062	nutrient storage
biological_process	GO:0170063	transmembrane transport from lysosomal lumen to cytosol
molecular_function	GO:0120531	prenyl diphosphate synthase activity
molecular_function	GO:0120533	glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] (non-phosphorylating) activity
molecular_function	GO:0120534	dermatan sulfotransferase activity
molecular_function	GO:0120536	heptaprenylglyceryl phosphate synthase activity
molecular_function	GO:0120537	3-demethylubiquinone 3-O-methyltransferase activity
molecular_function	GO:0120538	2-methoxy-6-polyprenolphenol 4-hydroxylase activity
molecular_function	GO:0120539	4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase activity
molecular_function	GO:0140002	histone H3K4me3 reader activity
molecular_function	GO:0140003	histone H3K36me3 reader activity
molecular_function	GO:0140004	histone H3Q5ser reader activity
molecular_function	GO:0140005	histone H4K20me2 reader activity
molecular_function	GO:0140006	histone H3 reader activity
molecular_function	GO:0140008	histone H4 reader activity
molecular_function	GO:0140011	histone H4K12ac reader activity
molecular_function	GO:0140012	histone H4K5ac reader activity
molecular_function	GO:0140015	histone H3K14ac reader activity
molecular_function	GO:0140017	histone H3K18cr reader activity
molecular_function	GO:0140019	histone H3K9cr reader activity
molecular_function	GO:0140038	histone H3K27cr reader activity
molecular_function	GO:0140044	histone H3K18ac reader activity
molecular_function	GO:0140046	histone H4K16ac reader activity
molecular_function	GO:0140054	histone H2A reader activity
molecular_function	GO:0140055	histone H4K8ac reader activity
molecular_function	GO:0140063	unmodified histone reader activity
molecular_function	GO:0140071	histone H2B reader activity
molecular_function	GO:0140072	histone H3K9ac reader activity
molecular_function	GO:0160220	D-alanine-(R)-lactate ligase activity
molecular_function	GO:0160222	D-alanine-D-serine ligase activity
molecular_function	GO:0160224	3-demethoxyubiquinone 3-hydroxylase (NADH) activity
molecular_function	GO:0160225	G-quadruplex unwinding activity
molecular_function	GO:0160228	bile acid-gated sodium channel activity
molecular_function	GO:0160229	peroxisome-endoplasmic reticulum membrane tether activity
molecular_function	GO:0180050	protein-mitochondrial outer membrane tethering activity
cellular_component	GO:0140047	specialized extracellular matrix
cellular_component	GO:0151001	tuft
cellular_component	GO:0160219	cortical endoplasmic reticulum membrane
cellular_component	GO:0160223	pyrenoid tubule
cellular_component	GO:0160226	oligosaccharyltransferase complex A
cellular_component	GO:0160227	oligosaccharyltransferase complex B
cellular_component	GO:0180049	Mrh5C translation activator complex

368 OBSOLETED TERMS CHANGES
biological_process	GO:0000717	nucleotide-excision repair, DNA duplex unwinding
biological_process	GO:0000718	nucleotide-excision repair, DNA damage removal
biological_process	GO:0006025	galactosaminoglycan biosynthetic process
biological_process	GO:0006028	galactosaminoglycan catabolic process
biological_process	GO:0006266	DNA ligation
biological_process	GO:0006268	DNA unwinding involved in DNA replication
biological_process	GO:0006288	base-excision repair, DNA ligation
biological_process	GO:0006844	acyl carnitine transport
biological_process	GO:0006880	intracellular sequestering of iron ion
biological_process	GO:0006881	extracellular sequestering of iron ion
biological_process	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
biological_process	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
biological_process	GO:0007253	cytoplasmic sequestering of NF-kappaB
biological_process	GO:0009689	induction of phytoalexin biosynthetic process
biological_process	GO:0010361	regulation of anion channel activity by blue light
biological_process	GO:0010501	RNA secondary structure unwinding
biological_process	GO:0010911	regulation of isomerase activity
biological_process	GO:0010912	positive regulation of isomerase activity
biological_process	GO:0010924	regulation of inositol-polyphosphate 5-phosphatase activity
biological_process	GO:0010979	regulation of vitamin D 24-hydroxylase activity
biological_process	GO:0014070	response to organic cyclic compound
biological_process	GO:0016061	regulation of light-activated channel activity
biological_process	GO:0018411	protein glucuronidation
biological_process	GO:0018412	protein O-glucuronidation
biological_process	GO:0019048	modulation by virus of host process
biological_process	GO:0019049	virus-mediated perturbation of host defense response
biological_process	GO:0019054	modulation by virus of host cellular process
biological_process	GO:0019325	anaerobic fructose catabolic process
biological_process	GO:0019463	glycine catabolic process to creatine
biological_process	GO:0019576	aerobic fructose catabolic process
biological_process	GO:0031279	regulation of cyclase activity
biological_process	GO:0031280	negative regulation of cyclase activity
biological_process	GO:0031551	regulation of brain-derived neurotrophic factor-activated receptor activity
biological_process	GO:0032069	regulation of nuclease activity
biological_process	GO:0032070	regulation of deoxyribonuclease activity
biological_process	GO:0032073	negative regulation of restriction endodeoxyribonuclease activity
biological_process	GO:0032084	regulation of type I site-specific deoxyribonuclease activity
biological_process	GO:0032085	regulation of type II site-specific deoxyribonuclease activity
biological_process	GO:0032086	regulation of type III site-specific deoxyribonuclease activity
biological_process	GO:0032087	regulation of type IV site-specific deoxyribonuclease activity
biological_process	GO:0032113	regulation of carbohydrate phosphatase activity
biological_process	GO:0032119	sequestering of zinc ion
biological_process	GO:0032415	regulation of sodium:proton antiporter activity
biological_process	GO:0032508	DNA duplex unwinding
biological_process	GO:0032768	regulation of monooxygenase activity
biological_process	GO:0032771	regulation of tyrosinase activity
biological_process	GO:0033131	regulation of glucokinase activity
biological_process	GO:0033341	regulation of collagen binding
biological_process	GO:0033343	positive regulation of collagen binding
biological_process	GO:0033670	regulation of NAD+ kinase activity
biological_process	GO:0034053	symbiont-mediated perturbation of host defense-related programmed cell death
biological_process	GO:0034054	symbiont-mediated suppression of host defense-related programmed cell death
biological_process	GO:0035227	regulation of glutamate-cysteine ligase activity
biological_process	GO:0035504	regulation of myosin light chain kinase activity
biological_process	GO:0035505	positive regulation of myosin light chain kinase activity
biological_process	GO:0035561	regulation of chromatin binding
biological_process	GO:0036167	phenotypic switching in response to host
biological_process	GO:0036234	deglucuronidation
biological_process	GO:0036235	acyl deglucuronidation
biological_process	GO:0036236	acyl glucuronidation
biological_process	GO:0036292	DNA rewinding
biological_process	GO:0039501	suppression by virus of host type I interferon production
biological_process	GO:0039519	modulation by virus of host autophagy
biological_process	GO:0039521	suppression by virus of host autophagy
biological_process	GO:0039637	catabolism by virus of host DNA
biological_process	GO:0042137	sequestering of neurotransmitter
biological_process	GO:0042192	methylmercury biosynthetic process
biological_process	GO:0042989	sequestering of actin monomers
biological_process	GO:0042994	cytoplasmic sequestering of transcription factor
biological_process	GO:0043095	regulation of GTP cyclohydrolase I activity
biological_process	GO:0043402	glucocorticoid mediated signaling pathway
biological_process	GO:0044349	DNA excision
biological_process	GO:0044362	negative regulation of molecular function in another organism
biological_process	GO:0044418	translocation of DNA into host
biological_process	GO:0044491	positive regulation of molecular function in another organism
biological_process	GO:0044501	perturbation of signal transduction in another organism
biological_process	GO:0044507	positive regulation of receptor activity in another organism
biological_process	GO:0044806	G-quadruplex DNA unwinding
biological_process	GO:0044831	modulation by virus of host cytokine production
biological_process	GO:0044833	modulation by virus of host protein transport
biological_process	GO:0044863	modulation by virus of host cell division
biological_process	GO:0044864	positive regulation by virus of host cell division
biological_process	GO:0044869	negative regulation by host of viral exo-alpha-sialidase activity
biological_process	GO:0046350	galactosaminoglycan metabolic process
biological_process	GO:0046414	organomercury biosynthetic process
biological_process	GO:0046774	suppression by virus of host intracellular interferon activity
biological_process	GO:0046775	suppression by virus of host cytokine production
biological_process	GO:0050788	sequestering of mercury
biological_process	GO:0051004	regulation of lipoprotein lipase activity
biological_process	GO:0051095	regulation of helicase activity
biological_process	GO:0051102	DNA ligation involved in DNA recombination
biological_process	GO:0051103	DNA ligation involved in DNA repair
biological_process	GO:0051104	DNA-dependent DNA replication DNA ligation
biological_process	GO:0051105	regulation of DNA ligation
biological_process	GO:0051106	positive regulation of DNA ligation
biological_process	GO:0051107	negative regulation of DNA ligation
biological_process	GO:0051220	cytoplasmic sequestering of protein
biological_process	GO:0051238	sequestering of metal ion
biological_process	GO:0051339	regulation of lyase activity
biological_process	GO:0051340	regulation of ligase activity
biological_process	GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity
biological_process	GO:0051352	negative regulation of ligase activity
biological_process	GO:0052089	modulation by symbiont of host salicylic acid-mediated defense response
biological_process	GO:0052173	response to defenses of other organism
biological_process	GO:0052318	regulation of phytoalexin metabolic process
biological_process	GO:0052319	regulation of phytoalexin biosynthetic process
biological_process	GO:0052320	positive regulation of phytoalexin metabolic process
biological_process	GO:0052321	negative regulation of phytoalexin metabolic process
biological_process	GO:0052323	negative regulation of phytoalexin biosynthetic process
biological_process	GO:0052403	negative regulation by host of symbiont catalytic activity
biological_process	GO:0052422	modulation by host of symbiont catalytic activity
biological_process	GO:0052472	modulation by host of symbiont transcription
biological_process	GO:0052695	cellular glucuronidation
biological_process	GO:0052696	flavonoid glucuronidation
biological_process	GO:0052697	xenobiotic glucuronidation
biological_process	GO:0060191	regulation of lipase activity
biological_process	GO:0060301	positive regulation of cytokine activity
biological_process	GO:0060380	regulation of single-stranded telomeric DNA binding
biological_process	GO:0060381	positive regulation of single-stranded telomeric DNA binding
biological_process	GO:0060549	regulation of fructose 1,6-bisphosphate 1-phosphatase activity
biological_process	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity
biological_process	GO:0060694	regulation of cholesterol transporter activity
biological_process	GO:0060701	negative regulation of ribonuclease activity
biological_process	GO:0060858	vesicle-mediated transport involved in floral organ abscission
biological_process	GO:0061960	regulation of heme oxygenase activity
biological_process	GO:0062002	regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity
biological_process	GO:0070413	trehalose metabolism in response to stress
biological_process	GO:0070414	trehalose metabolism in response to heat stress
biological_process	GO:0070415	trehalose metabolism in response to cold stress
biological_process	GO:0070416	trehalose metabolism in response to water deprivation
biological_process	GO:0071407	cellular response to organic cyclic compound
biological_process	GO:0075528	perturbation by virus of host immune response
biological_process	GO:0090219	negative regulation of lipid kinase activity
biological_process	GO:0090441	trehalose biosynthesis in response to heat stress
biological_process	GO:0090442	trehalose catabolism in response to heat stress
biological_process	GO:0097202	activation of cysteine-type endopeptidase activity
biological_process	GO:0097340	inhibition of cysteine-type endopeptidase activity
biological_process	GO:0097577	sequestering of iron ion
biological_process	GO:0097578	sequestering of copper ion
biological_process	GO:0097579	extracellular sequestering of copper ion
biological_process	GO:0097580	intracellular sequestering of copper ion
biological_process	GO:0097615	modulation by host of symbiont type IV pilus-dependent motility
biological_process	GO:0097616	positive regulation by host of symbiont type IV pilus-dependent motility
biological_process	GO:0106246	regulation of poly(A)-specific ribonuclease activity
biological_process	GO:0110112	regulation of lipid transporter activity
biological_process	GO:0120138	regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
biological_process	GO:0140133	symbiont-mediated suppression of host cytokine production
biological_process	GO:0141088	symbiont-mediated activation of host autophagy
biological_process	GO:0141132	defense response to host
biological_process	GO:0141199	GDP-mannose biosynthetic process from glucose
biological_process	GO:0150066	negative regulation of deacetylase activity
biological_process	GO:0150067	regulation of tubulin deacetylase activity
biological_process	GO:0150070	regulation of arginase activity
biological_process	GO:0150073	regulation of protein-glutamine gamma-glutamyltransferase activity
biological_process	GO:1900010	regulation of corticotropin-releasing hormone receptor activity
biological_process	GO:1900129	positive regulation of G-protein activated inward rectifier potassium channel activity
biological_process	GO:1900130	regulation of lipid binding
biological_process	GO:1900132	positive regulation of lipid binding
biological_process	GO:1900161	regulation of phospholipid scramblase activity
biological_process	GO:1900169	regulation of glucocorticoid mediated signaling pathway
biological_process	GO:1900170	negative regulation of glucocorticoid mediated signaling pathway
biological_process	GO:1900171	positive regulation of glucocorticoid mediated signaling pathway
biological_process	GO:1900259	regulation of RNA-dependent RNA polymerase activity
biological_process	GO:1900262	regulation of DNA-directed DNA polymerase activity
biological_process	GO:1900265	regulation of substance P receptor binding
biological_process	GO:1900266	negative regulation of substance P receptor binding
biological_process	GO:1900267	positive regulation of substance P receptor binding
biological_process	GO:1900276	regulation of proteinase activated receptor activity
biological_process	GO:1900757	regulation of D-amino-acid oxidase activity
biological_process	GO:1901004	ubiquinone-6 metabolic process
biological_process	GO:1901005	ubiquinone-6 catabolic process
biological_process	GO:1901006	ubiquinone-6 biosynthetic process
biological_process	GO:1901182	regulation of camalexin biosynthetic process
biological_process	GO:1901376	organic heteropentacyclic compound metabolic process
biological_process	GO:1901377	organic heteropentacyclic compound catabolic process
biological_process	GO:1901378	organic heteropentacyclic compound biosynthetic process
biological_process	GO:1901615	organic hydroxy compound metabolic process
biological_process	GO:1901616	organic hydroxy compound catabolic process
biological_process	GO:1901617	organic hydroxy compound biosynthetic process
biological_process	GO:1901664	regulation of NAD+ ADP-ribosyltransferase activity
biological_process	GO:1901839	regulation of RNA polymerase I regulatory region sequence-specific DNA binding
biological_process	GO:1901840	negative regulation of RNA polymerase I regulatory region sequence-specific DNA binding
biological_process	GO:1901878	positive regulation of calcium ion binding
biological_process	GO:1901917	regulation of exoribonuclease activity
biological_process	GO:1901918	negative regulation of exoribonuclease activity
biological_process	GO:1901968	regulation of polynucleotide 3'-phosphatase activity
biological_process	GO:1902162	regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
biological_process	GO:1902163	negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
biological_process	GO:1902164	positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
biological_process	GO:1902291	cell cycle DNA replication DNA ligation
biological_process	GO:1902297	cell cycle DNA replication DNA unwinding
biological_process	GO:1902320	nuclear DNA replication DNA duplex unwinding
biological_process	GO:1902327	bacterial-type DNA replication DNA ligation
biological_process	GO:1902332	bacterial-type DNA replication DNA duplex unwinding
biological_process	GO:1902333	nuclear DNA replication DNA ligation
biological_process	GO:1902392	regulation of exodeoxyribonuclease activity
biological_process	GO:1902429	positive regulation of water channel activity
biological_process	GO:1902571	regulation of serine-type peptidase activity
biological_process	GO:1902573	positive regulation of serine-type peptidase activity
biological_process	GO:1902595	regulation of DNA replication origin binding
biological_process	GO:1902606	regulation of large conductance calcium-activated potassium channel activity
biological_process	GO:1902619	regulation of microtubule minus-end binding
biological_process	GO:1902620	positive regulation of microtubule minus-end binding
biological_process	GO:1902769	regulation of choline O-acetyltransferase activity
biological_process	GO:1902799	regulation of phosphodiesterase I activity
biological_process	GO:1902941	regulation of voltage-gated chloride channel activity
biological_process	GO:1902949	positive regulation of tau-protein kinase activity
biological_process	GO:1902959	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
biological_process	GO:1902962	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
biological_process	GO:1902970	premeiotic DNA replication DNA duplex unwinding
biological_process	GO:1902971	mitotic DNA replication DNA duplex unwinding
biological_process	GO:1902972	premeiotic DNA replication DNA ligation
biological_process	GO:1902973	mitotic DNA replication DNA ligation
biological_process	GO:1903015	regulation of exo-alpha-sialidase activity
biological_process	GO:1903021	regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands
biological_process	GO:1903031	regulation of microtubule plus-end binding
biological_process	GO:1903032	negative regulation of microtubule plus-end binding
biological_process	GO:1903123	regulation of thioredoxin peroxidase activity
biological_process	GO:1903167	regulation of pyrroline-5-carboxylate reductase activity
biological_process	GO:1903168	positive regulation of pyrroline-5-carboxylate reductase activity
biological_process	GO:1903176	regulation of tyrosine 3-monooxygenase activity
biological_process	GO:1903178	positive regulation of tyrosine 3-monooxygenase activity
biological_process	GO:1903182	regulation of SUMO transferase activity
biological_process	GO:1903198	regulation of L-dopa decarboxylase activity
biological_process	GO:1903200	positive regulation of L-dopa decarboxylase activity
biological_process	GO:1903218	regulation of malate dehydrogenase (decarboxylating) (NADP+) activity
biological_process	GO:1903279	regulation of calcium:sodium antiporter activity
biological_process	GO:1903299	regulation of hexokinase activity
biological_process	GO:1903590	regulation of lysozyme activity
biological_process	GO:1903610	regulation of calcium-dependent ATPase activity
biological_process	GO:1903622	regulation of RNA polymerase III activity
biological_process	GO:1903630	regulation of aminoacyl-tRNA ligase activity
biological_process	GO:1903642	regulation of recombination hotspot binding
biological_process	GO:1903643	positive regulation of recombination hotspot binding
biological_process	GO:1903652	modulation by virus of host cytoplasmic transport
biological_process	GO:1903667	regulation of chemorepellent activity
biological_process	GO:1903730	regulation of phosphatidate phosphatase activity
biological_process	GO:1903762	positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
biological_process	GO:1903837	regulation of mRNA 3'-UTR binding
biological_process	GO:1903838	negative regulation of mRNA 3'-UTR binding
biological_process	GO:1903839	positive regulation of mRNA 3'-UTR binding
biological_process	GO:1903856	regulation of cytokinin dehydrogenase activity
biological_process	GO:1903868	regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity
biological_process	GO:1903932	regulation of DNA primase activity
biological_process	GO:1903952	regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
biological_process	GO:1903995	regulation of non-membrane spanning protein tyrosine kinase activity
biological_process	GO:1903997	positive regulation of non-membrane spanning protein tyrosine kinase activity
biological_process	GO:1904005	regulation of phospholipase D activity
biological_process	GO:1904029	regulation of cyclin-dependent protein kinase activity
biological_process	GO:1904041	regulation of cystathionine beta-synthase activity
biological_process	GO:1904217	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity
biological_process	GO:1904223	regulation of glucuronosyltransferase activity
biological_process	GO:1904226	regulation of glycogen synthase activity, transferring glucose-1-phosphate
biological_process	GO:1904232	regulation of aconitate hydratase activity
biological_process	GO:1904245	regulation of polynucleotide adenylyltransferase activity
biological_process	GO:1904254	regulation of iron ion transmembrane transporter activity
biological_process	GO:1904295	regulation of osmolarity-sensing cation channel activity
biological_process	GO:1904424	regulation of GTP binding
biological_process	GO:1904432	regulation of ferrous iron binding
biological_process	GO:1904433	negative regulation of ferrous iron binding
biological_process	GO:1904435	regulation of transferrin receptor binding
biological_process	GO:1904436	negative regulation of transferrin receptor binding
biological_process	GO:1904475	regulation of small GTPase binding
biological_process	GO:1904476	negative regulation of small GTPase binding
biological_process	GO:1904477	positive regulation of small GTPase binding
biological_process	GO:1904529	regulation of actin filament binding
biological_process	GO:1904572	negative regulation of mRNA binding
biological_process	GO:1904573	regulation of selenocysteine insertion sequence binding
biological_process	GO:1904574	negative regulation of selenocysteine insertion sequence binding
biological_process	GO:1904575	positive regulation of selenocysteine insertion sequence binding
biological_process	GO:1904603	regulation of advanced glycation end-product receptor activity
biological_process	GO:1904617	negative regulation of actin binding
biological_process	GO:1904618	positive regulation of actin binding
biological_process	GO:1904732	regulation of electron transfer activity
biological_process	GO:1904733	negative regulation of electron transfer activity
biological_process	GO:1904734	positive regulation of electron transfer activity
biological_process	GO:1904742	regulation of telomeric DNA binding
biological_process	GO:1904793	regulation of euchromatin binding
biological_process	GO:1904794	negative regulation of euchromatin binding
biological_process	GO:1904795	positive regulation of euchromatin binding
biological_process	GO:1904796	regulation of core promoter binding
biological_process	GO:1904875	regulation of DNA ligase activity
biological_process	GO:1904877	positive regulation of DNA ligase activity
biological_process	GO:1905117	regulation of ribonucleoside-diphosphate reductase activity
biological_process	GO:1905181	regulation of urease activity
biological_process	GO:1905214	regulation of RNA binding
biological_process	GO:1905245	regulation of aspartic-type peptidase activity
biological_process	GO:1905246	negative regulation of aspartic-type peptidase activity
biological_process	GO:1905255	regulation of RNA binding transcription factor activity
biological_process	GO:1905271	regulation of proton-transporting ATP synthase activity, rotational mechanism
biological_process	GO:1905407	regulation of creatine transmembrane transporter activity
biological_process	GO:1905462	regulation of DNA duplex unwinding
biological_process	GO:1905463	negative regulation of DNA duplex unwinding
biological_process	GO:1905464	positive regulation of DNA duplex unwinding
biological_process	GO:1905465	regulation of G-quadruplex DNA unwinding
biological_process	GO:1905466	negative regulation of G-quadruplex DNA unwinding
biological_process	GO:1905467	positive regulation of G-quadruplex DNA unwinding
biological_process	GO:1905494	negative regulation of G-quadruplex DNA binding
biological_process	GO:1905495	positive regulation of G-quadruplex DNA binding
biological_process	GO:1905496	regulation of triplex DNA binding
biological_process	GO:1905497	negative regulation of triplex DNA binding
biological_process	GO:1905498	positive regulation of triplex DNA binding
biological_process	GO:1905595	regulation of low-density lipoprotein particle receptor binding
biological_process	GO:1905610	regulation of mRNA cap binding
biological_process	GO:1905611	negative regulation of mRNA cap binding
biological_process	GO:1905687	regulation of diacylglycerol kinase activity
biological_process	GO:1905689	positive regulation of diacylglycerol kinase activity
biological_process	GO:1905767	regulation of double-stranded telomeric DNA binding
biological_process	GO:1905768	negative regulation of double-stranded telomeric DNA binding
biological_process	GO:1905769	positive regulation of double-stranded telomeric DNA binding
biological_process	GO:1905774	regulation of DNA helicase activity
biological_process	GO:1905776	positive regulation of DNA helicase activity
biological_process	GO:1905777	regulation of exonuclease activity
biological_process	GO:1905779	positive regulation of exonuclease activity
biological_process	GO:1905853	regulation of heparan sulfate binding
biological_process	GO:1905854	negative regulation of heparan sulfate binding
biological_process	GO:1905855	positive regulation of heparan sulfate binding
biological_process	GO:1905858	regulation of heparan sulfate proteoglycan binding
biological_process	GO:1905859	negative regulation of heparan sulfate proteoglycan binding
biological_process	GO:1905860	positive regulation of heparan sulfate proteoglycan binding
biological_process	GO:1905918	regulation of CoA-transferase activity
biological_process	GO:1990659	sequestering of manganese ion
biological_process	GO:1990969	modulation by host of viral RNA-binding transcription factor activity
biological_process	GO:2000116	regulation of cysteine-type endopeptidase activity
biological_process	GO:2000117	negative regulation of cysteine-type endopeptidase activity
biological_process	GO:2000275	regulation of oxidative phosphorylation uncoupler activity
biological_process	GO:2000361	regulation of prostaglandin-E synthase activity
biological_process	GO:2000371	regulation of DNA topoisomerase (ATP-hydrolyzing) activity
biological_process	GO:2000372	negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity
biological_process	GO:2000468	regulation of peroxidase activity
biological_process	GO:2000469	negative regulation of peroxidase activity
biological_process	GO:2000656	regulation of apolipoprotein binding
biological_process	GO:2000658	positive regulation of apolipoprotein binding
biological_process	GO:2001029	regulation of cellular glucuronidation
biological_process	GO:2001030	negative regulation of cellular glucuronidation
biological_process	GO:2001031	positive regulation of cellular glucuronidation
biological_process	GO:2001056	positive regulation of cysteine-type endopeptidase activity
biological_process	GO:2001144	regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
biological_process	GO:2001263	regulation of C-C chemokine binding
biological_process	GO:2001264	negative regulation of C-C chemokine binding
biological_process	GO:2001265	positive regulation of C-C chemokine binding
molecular_function	GO:0010012	steroid 22-alpha hydroxylase activity
molecular_function	GO:0016767	geranylgeranyl-diphosphate geranylgeranyltransferase activity
molecular_function	GO:0030374	nuclear receptor coactivator activity
molecular_function	GO:0033207	beta-1,4-N-acetylgalactosaminyltransferase activity
molecular_function	GO:0033208	UDP-N-acetylgalactosamine:N-acetylneuraminyl-alpha-2,3-galactosyl-beta-R 1,4-N-acetylgalactosaminyltransferase activity
molecular_function	GO:0033778	7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity
molecular_function	GO:0033779	5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity
molecular_function	GO:0033871	[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity
molecular_function	GO:0033872	[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity
molecular_function	GO:0046537	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
molecular_function	GO:0046538	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity
molecular_function	GO:0052608	echinenone 3-hydroxylase activity
molecular_function	GO:0052609	4-ketotorulene 3-hydroxylase activity
molecular_function	GO:0052610	beta-cryptoxanthin hydroxylase activity
molecular_function	GO:0052611	beta-carotene 3-hydroxylase activity
molecular_function	GO:0052612	adonirubin 3-hydroxylase activity
molecular_function	GO:0052613	canthaxanthin 3-hydroxylase activity
molecular_function	GO:0052739	phosphatidylserine 1-acylhydrolase activity
molecular_function	GO:0052850	NADPH-dependent dihydrocurcumin reductase activity
molecular_function	GO:0070643	vitamin D 25-hydroxylase activity
molecular_function	GO:0072555	17-beta-ketosteroid reductase (NADPH) activity
molecular_function	GO:0080076	caffeoyl CoA:S-adenosyl-L-methionine O-methyltransferase activity
molecular_function	GO:0097159	organic cyclic compound binding
molecular_function	GO:0102191	3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) [NAD(+)] activity
molecular_function	GO:0140536	nuclear receptor corepressor activity
molecular_function	GO:1901618	organic hydroxy compound transmembrane transporter activity
cellular_component	GO:0099053	activating signal cointegrator 1 complex

0 MERGED TERMS CHANGES

255 META CHANGES
biological_process	GO:0000162	L-tryptophan biosynthetic process
	name	L-tryptophan biosynthetic process	WAS	tryptophan biosynthetic process
	definition	"The chemical reactions and pathways resulting in the formation of L-tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; L-tryptophan is synthesized from chorismate via anthranilate." [GOC:mah, ISBN:0471331309, MetaCyc:TRPSYN-PWY]	WAS	"The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate." [GOC:mah, ISBN:0471331309, MetaCyc:TRPSYN-PWY]
	synonyms	"aromatic amino acid family biosynthetic process, anthranilate pathway" EXACT [];"L-tryptophan anabolism" EXACT [];"L-tryptophan biosynthesis" EXACT [];"tryptophan biosynthetic process" RELATED [];"tryptophan formation" EXACT [];"tryptophan synthesis" RELATED []	WAS	"aromatic amino acid family biosynthetic process, anthranilate pathway" EXACT [];"tryptophan anabolism" EXACT [];"tryptophan biosynthesis" EXACT [];"tryptophan formation" EXACT [];"tryptophan synthesis" EXACT []
biological_process	GO:0001576	globoside biosynthetic process
	definition	"The chemical reactions and pathways resulting in the formation of a glycosphingolipid with a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I)." [ISBN:0198506732]	WAS	"The chemical reactions and pathways resulting in the formation of a ceramide with a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I)." [ISBN:0198506732]
biological_process	GO:0001824	blastocyst development
	definition	"The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm. The blastula follows the morula and precedes the gastrula in the developmental sequence." [GOC:dph, ISBN:0124020607, ISBN:0198542771]	WAS	"The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm." [GOC:dph, ISBN:0124020607, ISBN:0198542771]
	synonyms	"blastula development" RELATED []	WAS	N/A
biological_process	GO:0001825	blastocyst formation
	synonyms	"blastula formation" RELATED []	WAS	N/A
biological_process	GO:0001832	blastocyst growth
	synonyms	"blastula growth" RELATED []	WAS	N/A
biological_process	GO:0001835	blastocyst hatching
	synonyms	"blastula hatching" RELATED []	WAS	N/A
biological_process	GO:0003012	muscle system process
	definition	"An organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers." [GOC:mtg_cardio]	WAS	"A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers." [GOC:mtg_cardio]
biological_process	GO:0003013	circulatory system process
	definition	"An organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism." [GOC:mtg_cardio]	WAS	"A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism." [GOC:mtg_cardio]
biological_process	GO:0003014	renal system process
	definition	"An organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila)." [GOC:cjm, GOC:mtg_cardio, GOC:mtg_kidney_jan10]	WAS	"A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila)." [GOC:cjm, GOC:mtg_cardio, GOC:mtg_kidney_jan10]
biological_process	GO:0006127	glycerol-3-phosphate shuttle
	name	glycerol-3-phosphate shuttle	WAS	glycerophosphate shuttle
	definition	"The process of transferring reducing equivalents from NADH in the cytosol into the mitochondria via glycerol-3-phosphate. Cytosolic glycerol-3-phosphate dehydrogenase uses NADH to convert dihydroxyacetone phosphate (DHAP) to glycerol-3-phosphate (G3P) in the cytosol; G3P then diffuses into the mitochondria where mitochondrial glycerol-3-phosphate dehydrogenase uses FAD to convert G3P back to DHAP; the electrons on the reduced FADH2 are then available for use in the electron transport chain, and DHAP returns to the cytosol to complete the cycle." [GOC:sjm, PMID:16368075]	WAS	"The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesize glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle." [GOC:jl, GOC:mtg_electron_transport, ISBN:0716720094, PMID:16368075]
	synonyms	"glycerol phosphate shuttle" EXACT [];"glycerophosphate shuttle" EXACT []	WAS	N/A
biological_process	GO:0006568	L-tryptophan metabolic process
	name	L-tryptophan metabolic process	WAS	tryptophan metabolic process
	synonyms	"tryptophan metabolic process" RELATED [];"tryptophan metabolism" RELATED []	WAS	"tryptophan metabolism" EXACT []
biological_process	GO:0006569	L-tryptophan catabolic process
	name	L-tryptophan catabolic process	WAS	tryptophan catabolic process
	definition	"The chemical reactions and pathways resulting in the breakdown of L-tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid." [ISBN:0198547684]	WAS	"The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid." [ISBN:0198547684]
	synonyms	"tryptophan breakdown" EXACT [];"tryptophan catabolic process" RELATED [];"tryptophan catabolic process, using tryptophanase" NARROW [];"tryptophan catabolism" EXACT [];"tryptophan catabolism, using tryptophanase" NARROW [];"tryptophan degradation" EXACT []	WAS	"tryptophan breakdown" EXACT [];"tryptophan catabolic process, using tryptophanase" NARROW [];"tryptophan catabolism" EXACT [];"tryptophan catabolism, using tryptophanase" NARROW [];"tryptophan degradation" EXACT []
biological_process	GO:0006601	creatine biosynthetic process
	definition	"The chemical reactions and pathways resulting in the formation of creatine, N-[amino(imino)methyl]-N-methylglycine. Creatine is formed by a process beginning with amidino group transfer from L-arginine to glycine to form guanidinoacetate, followed by methyl group transfer from S-adenosyl-L-methionine to guanidinoacetate; it is then is phosphorylated to form a pool that stores high energy phosphate for the replenishment of ATP during periods of high, or fluctuating energy demand. In animals, most creatine is transported to and used in muscle." [GOC:mah, MetaCyc:GLYCGREAT-PWY]	WAS	"The chemical reactions and pathways resulting in the formation of creatine, N-[amino(imino)methyl]-N-methylglycine. Creatine is formed by a process beginning with amidino group transfer from L-arginine to glycine to form guanidinoacetate, followed by methyl group transfer from S-adenosyl-L-methionine to guanidinoacetate; it is then is phosphorylated to form a pool that stores high energy phosphate for the replenishment of ATP during periods of high, or fluctuating energy demand. In animals, most creatine is transported to and used in muscle." [GOC:mah, MetaCyc:GLYCGREAT-PWY, MetaCyc:PWY-6158]
biological_process	GO:0006675	mannosyl-inositol phosphorylceramide metabolic process
	definition	"The chemical reactions and pathways involving mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative." [GOC:ai]	WAS	"The chemical reactions and pathways involving mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative." [GOC:ai, MetaCyc:MIPC]
biological_process	GO:0008153	4-aminobenzoate biosynthetic process
	name	4-aminobenzoate biosynthetic process	WAS	para-aminobenzoic acid biosynthetic process
	definition	"The chemical reactions and pathways resulting in the formation of 4-aminobenzoate, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins." [ISBN:0198506732, MetaCyc:PWY-6543, PMID:11377864, PMID:11960743]	WAS	"The chemical reactions and pathways resulting in the formation of para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins." [ISBN:0198506732, MetaCyc:PWY-6543, PMID:11377864, PMID:11960743]
	synonyms	"4-aminobenzoic acid biosynthesis" EXACT [];"4-aminobenzoic acid biosynthetic process" EXACT [];"p-aminobenzoic acid biosynthesis" EXACT [];"p-aminobenzoic acid biosynthetic process" EXACT [];"PABA biosynthesis" EXACT [];"PABA biosynthetic process" EXACT [];"para-aminobenzoic acid anabolism" EXACT [];"para-aminobenzoic acid biosynthesis" EXACT [];"para-aminobenzoic acid biosynthetic process" EXACT [];"para-aminobenzoic acid formation" EXACT [];"para-aminobenzoic acid synthesis" EXACT [];"vitamin Bx biosynthesis" EXACT [];"vitamin Bx biosynthetic process" EXACT []	WAS	"4-aminobenzoic acid biosynthesis" EXACT [];"4-aminobenzoic acid biosynthetic process" EXACT [];"p-aminobenzoic acid biosynthesis" EXACT [];"p-aminobenzoic acid biosynthetic process" EXACT [];"PABA biosynthesis" EXACT [];"PABA biosynthetic process" EXACT [];"para-aminobenzoic acid anabolism" EXACT [];"para-aminobenzoic acid biosynthesis" EXACT [];"para-aminobenzoic acid formation" EXACT [];"para-aminobenzoic acid synthesis" EXACT [];"vitamin Bx biosynthesis" EXACT [];"vitamin Bx biosynthetic process" EXACT []
biological_process	GO:0009626	plant-type hypersensitive response
	comment	Note that term is to be used to annotate gene products in the plant. To annotate symbiont gene products that induce the hypersensitive response, consider using 'effector-mediated activation of plant hypersensitive response by symbiont' ; GO:0080185.	WAS	Note that term is to be used to annotate gene products in the plant. To annotate symbiont gene products that induce the hypersensitive response, consider the biological process term 'modulation by symbiont of host defense-related programmed cell death ; GO:0034053'.
biological_process	GO:0010134	sulfate assimilation via adenylyl sulfate reduction
	definition	"The pathway by which inorganic sulfate is activated, reduced and incorporated into sulfated compounds, where the activated sulfate, adenylyl-sulfate, is reduced to sulfite by the activity of adenylyl-sulfate reductase." [MetaCyc:SULFMETII-PWY]	WAS	"The pathway by which inorganic sulfate is activated, reduced and incorporated into sulfated compounds, where the activated sulfate, adenylyl-sulfate, is reduced to sulfite by the activity of adenylyl-sulfate reductase." [EC:1.8.99.2]
biological_process	GO:0010889	regulation of triglyceride storage
	name	regulation of triglyceride storage	WAS	regulation of sequestering of triglyceride
	synonyms	"regulation of sequestering of triacylglycerol" EXACT [GOC:mah];"regulation of sequestering of triglyceride" EXACT [];"regulation of triacylglycerol sequestration" EXACT [GOC:dph, GOC:tb]	WAS	"regulation of sequestering of triacylglycerol" EXACT [GOC:mah];"regulation of triacylglycerol sequestration" EXACT [GOC:dph, GOC:tb]
biological_process	GO:0010890	positive regulation of triglyceride storage
	name	positive regulation of triglyceride storage	WAS	positive regulation of sequestering of triglyceride
	synonyms	"positive regulation of sequestering of triacylglycerol" EXACT [GOC:mah];"positive regulation of sequestering of triglyceride" EXACT [];"positive regulation of triglyceride sequestration" EXACT [GOC:dph, GOC:tb]	WAS	"positive regulation of sequestering of triacylglycerol" EXACT [GOC:mah];"positive regulation of triglyceride sequestration" EXACT [GOC:dph, GOC:tb]
biological_process	GO:0010891	negative regulation of triglyceride storage
	name	negative regulation of triglyceride storage	WAS	negative regulation of sequestering of triglyceride
	synonyms	"negative regulation of sequestering of triacylglycerol" EXACT [GOC:mah];"negative regulation of sequestering of triglyceride" EXACT [];"negative regulation of triglyceride sequestration" EXACT [GOC:dph, GOC:tb]	WAS	"negative regulation of sequestering of triacylglycerol" EXACT [GOC:mah];"negative regulation of triglyceride sequestration" EXACT [GOC:dph, GOC:tb]
biological_process	GO:0015014	heparan sulfate proteoglycan biosynthetic process, chain elongation
	name	heparan sulfate proteoglycan biosynthetic process, chain elongation	WAS	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
	synonyms	"heparan sulfate proteoglycan anabolism, polysaccharide chain anabolism" EXACT [];"heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process" EXACT [];"heparan sulfate proteoglycan chain elongation" EXACT [];"heparan sulfate proteoglycan formation, polysaccharide chain biosynthesis" EXACT [];"heparan sulfate proteoglycan formation, polysaccharide chain formation" EXACT [];"heparan sulfate proteoglycan synthesis, polysaccharide chain synthesis" EXACT [];"heparan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis" EXACT [];"heparan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process" EXACT [];"heparin proteoglycan biosynthetic process, polysaccharide chain biosynthetic process" RELATED []	WAS	"heparan sulfate proteoglycan anabolism, polysaccharide chain anabolism" EXACT [];"heparan sulfate proteoglycan chain elongation" EXACT [];"heparan sulfate proteoglycan formation, polysaccharide chain biosynthesis" EXACT [];"heparan sulfate proteoglycan formation, polysaccharide chain formation" EXACT [];"heparan sulfate proteoglycan synthesis, polysaccharide chain synthesis" EXACT [];"heparan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis" EXACT [];"heparan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process" EXACT [];"heparin proteoglycan biosynthetic process, polysaccharide chain biosynthetic process" RELATED []
biological_process	GO:0015787	UDP-glucuronate transmembrane transport
	name	UDP-glucuronate transmembrane transport	WAS	UDP-glucuronic acid transmembrane transport
	synonyms	"UDP-glucuronic acid transmembrane transport" EXACT [];"UDP-glucuronic acid transport" RELATED []	WAS	"UDP-glucuronic acid transport" RELATED []
biological_process	GO:0018868	2-aminobenzenesulfonate metabolic process
	definition	"The chemical reactions and pathways involving 2-aminobenzenesulfonate, aniline-o-sulfonic acid, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines." [GOC:curators]	WAS	"The chemical reactions and pathways involving 2-aminobenzenesulfonate, aniline-o-sulfonic acid, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines." [UM-BBD_pathwayID:abs]
biological_process	GO:0018873	atrazine metabolic process
	definition	"The chemical reactions and pathways involving atrazine, a triazine ring-containing compound, widely used as a herbicide." [GOC:curators]	WAS	"The chemical reactions and pathways involving atrazine, a triazine ring-containing compound, widely used as a herbicide." [UM-BBD_pathwayID:atr]
biological_process	GO:0018882	(+)-camphor metabolic process
	definition	"The chemical reactions and pathways involving (+)-camphor, a bicyclic monoterpene ketone which is one of the major components in the leaves of common sage. Camphor exists in two enantiomers, but the (+)-isomer is more widely distributed." [GOC:curators]	WAS	"The chemical reactions and pathways involving (+)-camphor, a bicyclic monoterpene ketone which is one of the major components in the leaves of common sage. Camphor exists in two enantiomers, but the (+)-isomer is more widely distributed." [UM-BBD_pathwayID:cam]
biological_process	GO:0018901	2,4-dichlorophenoxyacetic acid metabolic process
	definition	"The chemical reactions and pathways involving 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds." [GOC:curators]	WAS	"The chemical reactions and pathways involving 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds." [UM-BBD_pathwayID:2\,4d]
biological_process	GO:0018952	parathion metabolic process
	definition	"The chemical reactions and pathways involving parathion, a highly toxic organophosphate compound formerly used as a broad spectrum insecticide, acaricide, fumigant and nematocide. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition." [GOC:curators]	WAS	"The chemical reactions and pathways involving parathion, a highly toxic organophosphate compound formerly used as a broad spectrum insecticide, acaricide, fumigant and nematocide. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition." [UM-BBD_pathwayID:pthn]
biological_process	GO:0018970	toluene metabolic process
	definition	"The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products such as gasoline and commonly used as a paint thinning agent and in other solvent applications." [GOC:curators]	WAS	"The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products such as gasoline and commonly used as a paint thinning agent and in other solvent applications." [UM-BBD_pathwayID:tol]
biological_process	GO:0018983	Z-phenylacetaldoxime metabolic process
	definition	"The chemical reactions and pathways involving Z-phenylacetaldoxime, a member of the glucosinolate group of compounds, a class of natural products that are gaining increasing interest as cancer-preventing agents and crop protectants." [UM-BBD_pathwayID:pao]	WAS	"The chemical reactions and pathways involving Z-phenylacetaldoxime, a member of the glucosinolate group of compounds, a class of natural products that are gaining increasing interest as cancer-preventing agents and crop protectants." [UM-BBD_pathwayID:car]
biological_process	GO:0019087	symbiont-mediated transformation of host cell
	name	symbiont-mediated transformation of host cell	WAS	transformation of host cell by virus
	definition	"A symbiont-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication. Usually mediated by viruses." [ISBN:0781702534, PMID:11119620, PMID:18366075, PMID:24373315]	WAS	"A virus-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication." [ISBN:0781702534, PMID:11119620, PMID:18366075, PMID:24373315]
	synonyms	"host cell immortalization" EXACT [];"host cell transformation" EXACT [];"immortalization of host cell" EXACT [];"immortalization of host cell by virus" RELATED [];"transformation of host cell" EXACT [];"transformation of host cell by virus" EXACT [];"viral immortalization" EXACT [];"viral transformation" EXACT [];"viral transformation of host cell" EXACT [];"virus-mediated transformation of host cell" RELATED []	WAS	"host cell immortalization" EXACT [];"host cell transformation" EXACT [];"immortalization of host cell" EXACT [];"immortalization of host cell by virus" RELATED [];"transformation of host cell" EXACT [];"viral immortalization" EXACT [];"viral transformation" EXACT [];"viral transformation of host cell" EXACT []
biological_process	GO:0019329	ammonia oxidation
	definition	"The chemical reactions and pathways by which ammonia or ammonium is converted to molecular nitrogen or another nitrogen compound, with accompanying loss of electrons." [GOC:mah]	WAS	"The chemical reactions and pathways by which ammonia or ammonium is converted to molecular nitrogen or another nitrogen compound, with accompanying loss of electrons." [GOC:mah, MetaCyc:AMMOXID-PWY, MetaCyc:P303-PWY, MetaCyc:PWY-2242]
biological_process	GO:0019339	parathion catabolic process
	definition	"The chemical reactions and pathways resulting in the breakdown of parathion, a highly toxic organophosphate compound. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition." [MetaCyc:PARATHION-DEGRADATION-PWY]	WAS	"The chemical reactions and pathways resulting in the breakdown of parathion, a highly toxic organophosphate compound. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition." [UM-BBD_pathwayID:pthn]
biological_process	GO:0019381	atrazine catabolic process
	definition	"The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide." [GOC:jl, MetaCyc:PWY-5724]	WAS	"The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide." [GOC:jl, UM-BBD_pathwayID:atr]
biological_process	GO:0019383	(+)-camphor catabolic process
	definition	"The chemical reactions and pathways resulting in the breakdown of (+)-camphor, a bicyclic monoterpene ketone." [MetaCyc:P601-PWY]	WAS	"The chemical reactions and pathways resulting in the breakdown of (+)-camphor, a bicyclic monoterpene ketone." [UM-BBD_pathwayID:cam]
biological_process	GO:0019391	glucuronoside catabolic process
	is_obsolete	False	WAS	True
	name	glucuronoside catabolic process	WAS	obsolete glucuronoside catabolic process
	definition	"The chemical reactions and pathways resulting in the breakdown of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue." [PMID:28389557]	WAS	"OBSOLETE. The chemical reactions and pathways resulting in the breakdown of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue." [ISBN:0198506732]
	comment	Note that this term was reinstated from obsolete.	WAS	The reason for obsoletion is that this term represents a molecular function.
biological_process	GO:0019417	sulfur oxidation
	definition	"The chemical reactions and pathways resulting the addition of oxygen to elemental sulfur." [GOC:jl]	WAS	"The chemical reactions and pathways resulting the addition of oxygen to elemental sulfur." [GOC:jl, MetaCyc:FESULFOX-PWY, MetaCyc:SULFUROX-PWY]
biological_process	GO:0019434	sophorosyloxydocosanoate metabolic process
	definition	"The chemical reactions and pathways involving sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate, an aromatic hydrocarbon." [GOC:curators]	WAS	"The chemical reactions and pathways involving sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate, an aromatic hydrocarbon." [MetaCyc:DIGLUCODIACETYL-DOCOSANOATE]
biological_process	GO:0019440	L-tryptophan catabolic process to indole-3-acetate
	name	L-tryptophan catabolic process to indole-3-acetate	WAS	tryptophan catabolic process to indole-3-acetate
	definition	"The chemical reactions and pathways resulting in the breakdown of L-tryptophan into other compounds, including indole-3-acetate." [GOC:go_curators]	WAS	"The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including indole-3-acetate." [GOC:go_curators]
	synonyms	"tryptophan breakdown to indole-3-acetate" EXACT [];"tryptophan catabolic process to IAA" EXACT [];"tryptophan catabolic process to indole-3-acetate" EXACT [];"tryptophan catabolic process to indoleacetic acid" EXACT [];"tryptophan catabolism to indoleacetic acid" EXACT [];"tryptophan degradation to indole-3-acetate" EXACT []	WAS	"tryptophan breakdown to indole-3-acetate" EXACT [];"tryptophan catabolic process to IAA" EXACT [];"tryptophan catabolic process to indoleacetic acid" EXACT [];"tryptophan catabolism to indoleacetic acid" EXACT [];"tryptophan degradation to indole-3-acetate" EXACT []
biological_process	GO:0019441	L-tryptophan catabolic process to kynurenine
	name	L-tryptophan catabolic process to kynurenine	WAS	tryptophan catabolic process to kynurenine
	definition	"The chemical reactions and pathways resulting in the breakdown of L-tryptophan into other compounds, including kynurenine." [GOC:go_curators]	WAS	"The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including kynurenine." [GOC:go_curators]
	synonyms	"tryptophan breakdown to kynurenine" EXACT [];"tryptophan catabolic process to kynurenine" EXACT [];"tryptophan degradation to kynurenine" EXACT []	WAS	"tryptophan breakdown to kynurenine" EXACT [];"tryptophan degradation to kynurenine" EXACT []
biological_process	GO:0019442	L-tryptophan catabolic process to acetyl-CoA
	name	L-tryptophan catabolic process to acetyl-CoA	WAS	tryptophan catabolic process to acetyl-CoA
	definition	"The chemical reactions and pathways resulting in the breakdown of L-tryptophan into other compounds, including acetyl-CoA." [GOC:go_curators]	WAS	"The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including acetyl-CoA." [GOC:go_curators]
	synonyms	"tryptophan breakdown to acetyl-CoA" EXACT [];"tryptophan catabolic process to acetyl-CoA" EXACT [];"tryptophan degradation to acetyl-CoA" EXACT []	WAS	"tryptophan breakdown to acetyl-CoA" EXACT [];"tryptophan degradation to acetyl-CoA" EXACT []
biological_process	GO:0019444	L-tryptophan catabolic process to catechol
	name	L-tryptophan catabolic process to catechol	WAS	tryptophan catabolic process to catechol
	definition	"The chemical reactions and pathways resulting in the breakdown of L-tryptophan into other compounds, including catechol." [GOC:go_curators]	WAS	"The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including catechol." [GOC:go_curators]
	synonyms	"tryptophan breakdown to catechol" EXACT [];"tryptophan catabolic process to catechol" EXACT [];"tryptophan degradation to catechol" EXACT []	WAS	"tryptophan breakdown to catechol" EXACT [];"tryptophan degradation to catechol" EXACT []
biological_process	GO:0019490	2-aminobenzenesulfonate desulfonation
	definition	"The removal of the sulfonate group from 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines." [MetaCyc:2ASDEG-PWY]	WAS	"The removal of the sulfonate group from 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines." [UM-BBD_pathwayID:abs]
biological_process	GO:0019517	L-threonine catabolic process to D-lactate
	definition	"The chemical reactions and pathways resulting in the breakdown of L- threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound methylglyoxal, which is subsequently converted to D-lactate." [GOC:bf, GOC:jl, MetaCyc:THRDLCTCAT-PWY]	WAS	"The chemical reactions and pathways resulting in the breakdown of L- threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound methylglyoxal, which is subsequently converted to D-lactate." [GOC:bf, GOC:jl, MetaCyc:PWY-901, MetaCyc:THRDLCTCAT-PWY]
biological_process	GO:0019662	non-glycolytic fermentation
	definition	"Fermentation that does not include the anaerobic conversion of glucose to pyruvate via the glycolytic pathway." [GOC:jl]	WAS	"Fermentation that does not include the anaerobic conversion of glucose to pyruvate via the glycolytic pathway." [GOC:jl, MetaCyc:Fermentation]
biological_process	GO:0019665	anaerobic amino acid catabolic process
	definition	"The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids, yielding energy in the form of ATP." [GOC:curators, GOC:jl]	WAS	"The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids, yielding energy in the form of ATP." [GOC:curators, GOC:jl, MetaCyc:Fermentation]
biological_process	GO:0030730	triglyceride storage
	name	triglyceride storage	WAS	sequestering of triglyceride
	synonyms	"retention of triacylglycerol" EXACT [];"retention of triglyceride" EXACT [];"sequestering of triacylglycerol" EXACT [];"sequestering of triglyceride" EXACT [];"sequestration of triacylglycerol" EXACT [];"sequestration of triglyceride" EXACT [];"storage of triacylglycerol" EXACT [];"storage of triglyceride" EXACT [];"triacylglycerol retention" EXACT [];"triacylglycerol sequestering" EXACT [];"triacylglycerol sequestration" EXACT [];"triacylglycerol storage" EXACT [];"triglyceride retention" EXACT [];"triglyceride sequestering" EXACT [];"triglyceride sequestration" EXACT []	WAS	"retention of triacylglycerol" EXACT [];"retention of triglyceride" EXACT [];"sequestering of triacylglycerol" EXACT [];"sequestration of triacylglycerol" EXACT [];"sequestration of triglyceride" EXACT [];"storage of triacylglycerol" EXACT [];"storage of triglyceride" EXACT [];"triacylglycerol retention" EXACT [];"triacylglycerol sequestering" EXACT [];"triacylglycerol sequestration" EXACT [];"triacylglycerol storage" EXACT [];"triglyceride retention" EXACT [];"triglyceride sequestering" EXACT [];"triglyceride sequestration" EXACT [];"triglyceride storage" EXACT []
biological_process	GO:0031959	nuclear receptor-mediated mineralocorticoid signaling pathway
	definition	"A nuclear receptor-mediated signaling pathway initiated by a mineralocorticoid binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription." [PMID:11027914, PMID:12606724, PMID:15240347]	WAS	"A nuclear receptor-mediated signaling pathway initiated by a mineralocorticoid binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription." [PMID:11027914, PMID:12606724]
biological_process	GO:0033108	mitochondrial respiratory chain complex assembly
	definition	"The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex or between respiratory chain complexes to form high-order structures." [GOC:mah]	WAS	"The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex." [GOC:mah]
biological_process	GO:0033302	quercetin O-glucoside metabolic process
	definition	"The chemical reactions and pathways involving O-glucosylated derivatives of quercetin." [GOC:mah]	WAS	"The chemical reactions and pathways involving O-glucosylated derivatives of quercetin." [GOC:mah, MetaCyc:PWY-5321]
biological_process	GO:0033321	homomethionine metabolic process
	definition	"The chemical reactions and pathways involving homomethionine, a non-protein amino acid synthesized from methionine via chain elongation." [GOC:mah]	WAS	"The chemical reactions and pathways involving homomethionine, a non-protein amino acid synthesized from methionine via chain elongation." [GOC:mah, MetaCyc:PWY-1186]
biological_process	GO:0033322	L-homomethionine biosynthetic process
	name	L-homomethionine biosynthetic process	WAS	homomethionine biosynthetic process
	definition	"The chemical reactions and pathways resulting in the formation of L-homomethionine, a non-protein amino acid synthesized from L-methionine via chain elongation." [GOC:mah, MetaCyc:PWY-1186]	WAS	"The chemical reactions and pathways resulting in the formation of homomethionine, a non-protein amino acid synthesized from methionine via chain elongation." [GOC:mah, MetaCyc:PWY-1186]
	synonyms	"homomethionine anabolism" EXACT [];"homomethionine biosynthesis" EXACT [];"homomethionine biosynthetic process" EXACT [];"homomethionine formation" EXACT [];"homomethionine synthesis" EXACT []	WAS	"homomethionine anabolism" EXACT [];"homomethionine biosynthesis" EXACT [];"homomethionine formation" EXACT [];"homomethionine synthesis" EXACT []
biological_process	GO:0033329	kaempferol O-glucoside metabolic process
	definition	"The chemical reactions and pathways involving O-glucosylated derivatives of kaempferol." [GOC:mah]	WAS	"The chemical reactions and pathways involving O-glucosylated derivatives of kaempferol." [GOC:mah, MetaCyc:PWY-5320]
biological_process	GO:0033331	ent-kaurene metabolic process
	definition	"The chemical reactions and pathways involving ent-kaur-16-ene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins." [GOC:mah, PMID:17064690]	WAS	"The chemical reactions and pathways involving ent-kaur-16-ene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins." [GOC:mah, MetaCyc:PWY-5032, PMID:17064690]
biological_process	GO:0033359	lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate
	definition	"The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and N-succinyl-2-amino-6-ketopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps." [GOC:mah, MetaCyc:DAPLYSINESYN-PWY]	WAS	"The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and N-succinyl-2-amino-6-ketopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps." [GOC:mah, MetaCyc:DAPLYSINESYN-PWY-]
biological_process	GO:0033383	geranyl diphosphate metabolic process
	definition	"The chemical reactions and pathways involving geranyl diphosphate, the universal precursor of the monoterpenes." [GOC:mah]	WAS	"The chemical reactions and pathways involving geranyl diphosphate, the universal precursor of the monoterpenes." [GOC:mah, MetaCyc:PWY-5122]
biological_process	GO:0033385	geranylgeranyl diphosphate metabolic process
	definition	"The chemical reactions and pathways involving geranylgeranyl diphosphate, a polyprenol compound involved in the biosynthesis of a variety of terpenoids including chlorophylls, carotenoids, tocopherols, plastoquinones, and the plant hormones gibberellins." [GOC:mah]	WAS	"The chemical reactions and pathways involving geranylgeranyl diphosphate, a polyprenol compound involved in the biosynthesis of a variety of terpenoids including chlorophylls, carotenoids, tocopherols, plastoquinones, and the plant hormones gibberellins." [GOC:mah, MetaCyc:PWY-5120]
biological_process	GO:0033386	geranylgeranyl diphosphate biosynthetic process
	definition	"The chemical reactions and pathways resulting in the formation of geranylgeranyl diphosphate." [GOC:mah]	WAS	"The chemical reactions and pathways resulting in the formation of geranylgeranyl diphosphate." [GOC:mah, MetaCyc:PWY-5120]
biological_process	GO:0033387	putrescine biosynthetic process from arginine, via ornithine
	name	putrescine biosynthetic process from arginine, via ornithine	WAS	putrescine biosynthetic process from ornithine
	definition	"The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from arginine, via decarboxylation of ornithine." [GOC:mah, MetaCyc:PWY-46]	WAS	"The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane by decarboxylation of ornithine." [GOC:mah, MetaCyc:PWY-46]
	synonyms	"putrescine anabolism from ornithine" EXACT [];"putrescine biosynthesis from ornithine" EXACT [];"putrescine biosynthetic process from ornithine" EXACT [];"putrescine formation from ornithine" EXACT [];"putrescine synthesis from ornithine" EXACT []	WAS	"putrescine anabolism from ornithine" EXACT [];"putrescine biosynthesis from ornithine" EXACT [];"putrescine formation from ornithine" EXACT [];"putrescine synthesis from ornithine" EXACT []
biological_process	GO:0033388	putrescine biosynthetic process from arginine
	definition	"The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine." [GOC:mah]	WAS	"The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine." [GOC:mah, MetaCyc:PWY-46]
biological_process	GO:0033389	putrescine biosynthetic process from arginine, via agmatine
	name	putrescine biosynthetic process from arginine, via agmatine	WAS	putrescine biosynthetic process from arginine, using agmatinase
	definition	"The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from arginine via agmatine." [GOC:mah, MetaCyc:PWY-40]	WAS	"The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in a single enzymatic step." [GOC:mah, MetaCyc:PWY-40]
	synonyms	"putrescine anabolism from arginine, using agmatinase" EXACT [];"putrescine biosynthesis from arginine, using agmatinase" EXACT [];"putrescine biosynthetic process from arginine, using agmatinase" EXACT [];"putrescine formation from arginine, using agmatinase" EXACT [];"putrescine synthesis from arginine, using agmatinase" EXACT []	WAS	"putrescine anabolism from arginine, using agmatinase" EXACT [];"putrescine biosynthesis from arginine, using agmatinase" EXACT [];"putrescine formation from arginine, using agmatinase" EXACT [];"putrescine synthesis from arginine, using agmatinase" EXACT []
biological_process	GO:0033499	galactose catabolic process via UDP-galactose
	definition	"The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate UDP-galactose." [GOC:mah]	WAS	"The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate UDP-galactose." [GOC:mah, MetaCyc:PWY-3821]
biological_process	GO:0033621	nuclear mRNA surveillance of meiosis-specific transcripts
	name	nuclear mRNA surveillance of meiosis-specific transcripts	WAS	nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts
	synonyms	"degradation of meiosis-specific transcripts" EXACT [];"mRNA breakdown, meiosis-specific transcripts" EXACT [];"mRNA catabolism, meiosis-specific transcripts" EXACT [];"mRNA degradation, meiosis-specific transcripts" EXACT [];"nuclear mRNA catabolic process, meiosis-specific transcripts" EXACT [];"nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts" EXACT []	WAS	"degradation of meiosis-specific transcripts" EXACT [];"mRNA breakdown, meiosis-specific transcripts" EXACT [];"mRNA catabolism, meiosis-specific transcripts" EXACT [];"mRNA degradation, meiosis-specific transcripts" EXACT [];"nuclear mRNA catabolic process, meiosis-specific transcripts" EXACT []
biological_process	GO:0034055	effector-mediated activation of host programmed cell death by symbiont
	name	effector-mediated activation of host programmed cell death by symbiont	WAS	effector-mediated activation of programmed cell death in host
	synonyms	"activation by symbiont of host defense-related programmed cell death" NARROW [GOC:pamgo_curators];"effector-mediated activation of programmed cell death in host" EXACT [];"effector-mediated induction of programmed cell death in host" EXACT [];"enhancement by symbiont of host defense-related programmed cell death" NARROW [GOC:pamgo_curators];"positive regulation by symbiont of host defense-related PCD" EXACT [GOC:pamgo_curators];"positive regulation by symbiont of host defense-related programmed cell death" RELATED [];"stimulation by symbiont of host defense-related programmed cell death" NARROW [GOC:pamgo_curators];"up regulation by symbiont of host defense-related programmed cell death" EXACT [GOC:pamgo_curators];"up-regulation by symbiont of host defense-related programmed cell death" EXACT [GOC:pamgo_curators];"upregulation by symbiont of host defense-related programmed cell death" EXACT [GOC:pamgo_curators]	WAS	"activation by symbiont of host defense-related programmed cell death" NARROW [GOC:pamgo_curators];"effector-mediated induction of programmed cell death in host" EXACT [];"enhancement by symbiont of host defense-related programmed cell death" NARROW [GOC:pamgo_curators];"positive regulation by symbiont of host defense-related PCD" EXACT [GOC:pamgo_curators];"positive regulation by symbiont of host defense-related programmed cell death" RELATED [];"stimulation by symbiont of host defense-related programmed cell death" NARROW [GOC:pamgo_curators];"up regulation by symbiont of host defense-related programmed cell death" EXACT [GOC:pamgo_curators];"up-regulation by symbiont of host defense-related programmed cell death" EXACT [GOC:pamgo_curators];"upregulation by symbiont of host defense-related programmed cell death" EXACT [GOC:pamgo_curators]
biological_process	GO:0034077	butanediol metabolic process
	definition	"The chemical reactions and pathways involving butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3." [ISBN:0911910123]	WAS	"The chemical reactions and pathways involving butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3." [ISBN:0911910123, MetaCyc:BUTANEDIOL]
biological_process	GO:0034078	butanediol catabolic process
	definition	"The chemical reactions and pathways resulting in the breakdown of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3." [GOC:mah, ISBN:0911910123]	WAS	"The chemical reactions and pathways resulting in the breakdown of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3." [GOC:mah, ISBN:0911910123, MetaCyc:125-PWY, MetaCyc:BUTANEDIOL]
biological_process	GO:0034079	butanediol biosynthetic process
	definition	"The chemical reactions and pathways resulting in the formation of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3." [GOC:mah, ISBN:0911910123, MetaCyc:P125-PWY]	WAS	"The chemical reactions and pathways resulting in the formation of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3." [GOC:mah, ISBN:0911910123, MetaCyc:BUTANEDIOL, MetaCyc:P125-PWY]
biological_process	GO:0039520	symbiont-mediated activation of host autophagy
	name	symbiont-mediated activation of host autophagy	WAS	induction by virus of host autophagy
	definition	"A process in which a symbiont initiates, promotes, or enhances the normal execution of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. For example, some viruses are able to activate host autophagy as a cellular survival mechanism, hence delaying or inhibiting apoptosis." [GOC:bf, GOC:sp, VZ:846]	WAS	"Any process in which a virus activates or increases the frequency, rate or extent of autophagy in the host." [GOC:bf, GOC:sp, UniProtKB-KW:KW-1072, VZ:846]
	synonyms	"activation of host autophagy by virus" EXACT [UniProtKB-KW:KW-1072];"autophagy of host cells involved in interaction with symbiont" RELATED [];"induction by virus of host autophagy" NARROW [];"positive regulation by virus of host autophagy" BROAD [GOC:bf]	WAS	"activation of host autophagy by virus" EXACT [UniProtKB-KW:KW-1072];"autophagy of host cells involved in interaction with symbiont" RELATED [];"positive regulation by virus of host autophagy" BROAD [GOC:bf]
biological_process	GO:0039522	symbiont-mediated suppression of host mRNA export from nucleus
	definition	"A process in which a symbiont inhibits or disrupts the normal movement of mRNA from the nucleus to the cytoplasm of the host cell, leading to shutoff of host protein expression. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:bf, GOC:sp, PMID:22334672]	WAS	"A process in which a symbiont inhibits or disrupts the normal movement of mRNA from the nucleus to the cytoplasm of the host cell, leading to shutoff of host protein expression. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:bf, GOC:sp]
biological_process	GO:0039587	symbiont-mediated-mediated suppression of host tetherin activity
	name	symbiont-mediated-mediated suppression of host tetherin activity	WAS	suppression by virus of host tetherin activity
	definition	"Any process in which a symbiont stops, prevents, or reduces the activity of host tetherin activity. Tetherin (also known as BST2) is an alpha interferon-inducible cellular factor that impairs the release of many enveloped viruses. By blocking tetherin activity, many viruses circumvent its antiviral effects." [PMID:22493439]	WAS	"Any process in which a virus stops, prevents, or reduces the activity of host tetherin activity. Tetherin (also known as BST2) is an alpha interferon-inducible cellular factor that impairs the release of many enveloped viruses. By blocking tetherin activity, many viruses circumvent its antiviral effects." [PMID:22493439]
	synonyms	"evasion of suppression of viral release by host via inhibition of host tetherin activity" NARROW [];"inhibition of host BST2/Tetherin by virus" EXACT [];"suppression by virus of host tetherin activity" EXACT []	WAS	"inhibition of host BST2/Tetherin by virus" EXACT []
biological_process	GO:0039635	symbiont-mediated suppression of host peptidoglycan biosynthetic process
	name	symbiont-mediated suppression of host peptidoglycan biosynthetic process	WAS	suppression by virus of host peptidoglycan biosynthetic process
	definition	"Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls, and phages have mechanisms to disrupt their host's cell walls." [GOC:bf, GOC:bm, GOC:jl]	WAS	"Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls." [GOC:bf, GOC:bm, GOC:jl]
	synonyms	"suppression by virus of host peptidoglycan biosynthetic process" NARROW [];"viral inhibition of host peptidoglycan biosynthesis" RELATED [GOC:bf]	WAS	"viral inhibition of host peptidoglycan biosynthesis" RELATED [GOC:bf]
biological_process	GO:0039636	symbiont-mediated suppression of host cell wall biogenesis
	name	symbiont-mediated suppression of host cell wall biogenesis	WAS	suppression by virus of host cell wall biogenesis
	synonyms	"suppression by virus of host cell wall biogenesis" NARROW []	WAS	N/A
biological_process	GO:0039671	symbiont-mediated perturbation of host natural killer cell mediated immune response
	name	symbiont-mediated perturbation of host natural killer cell mediated immune response	WAS	evasion by virus of host natural killer cell activity
	definition	"A process in which a symbiont alters or subverts the natural killer cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:bf, GOC:jl, PMID:15640804, PMID:18688275, UniProtKB-KW:KW-1131]	WAS	"Any process by which a virus avoids the effects mediated by the host organism's natural killer (NK) cells." [GOC:bf, GOC:jl, PMID:15640804, PMID:18688275, UniProtKB-KW:KW-1131]
	synonyms	"evasion by virus of host natural killer cell activity" NARROW [];"evasion by virus of host natural killer cell response" EXACT [];"evasion by virus of host NK cell killing" EXACT [GOC:bf];"modulation of host NK-cell activity by virus" RELATED [UniProtKB-KW:KW-1131];"protection by virus against host NK cell cytotoxicity" EXACT [PMID:12782710];"suppression by virus of host natural killer cell function" NARROW [PMID:15640804];"viral immunoevasion of host NK cell" NARROW [GOC:bf]	WAS	"evasion by virus of host natural killer cell response" EXACT [];"evasion by virus of host NK cell killing" EXACT [GOC:bf];"modulation of host NK-cell activity by virus" RELATED [UniProtKB-KW:KW-1131];"protection by virus against host NK cell cytotoxicity" EXACT [PMID:12782710];"suppression by virus of host natural killer cell function" EXACT [PMID:15640804];"viral immunoevasion of host NK cell" EXACT [GOC:bf]
biological_process	GO:0039672	symbiont-mediated suppression of host natural killer cell activation
	name	symbiont-mediated suppression of host natural killer cell activation	WAS	suppression by virus of host natural killer cell activation
	definition	"A process in which a symbiont interferes with, inhibits or disrupts natural killer cell activation in the host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:10799855]	WAS	"Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation in the host." [GOC:bf, GOC:jl]
	synonyms	"suppression by virus of host natural killer cell activation" NARROW [];"suppression by virus of host NK-cell activation" EXACT []	WAS	"suppression by virus of host NK-cell activation" EXACT [GOC:bf, GOC:jl]
biological_process	GO:0039673	symbiont-mediated suppression of host dendritic cell mediated immune response
	name	symbiont-mediated suppression of host dendritic cell mediated immune response	WAS	evasion by virus of host dendritic cell activity
	definition	"A process in which a symbiont inhibits or disrupts the dendritic cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:bf, GOC:jl, UniProtKB-KW:KW-1118]	WAS	"Any process by which a virus avoids the effects mediated by the host organism's dendritic cells." [GOC:bf, GOC:jl, UniProtKB-KW:KW-1118]
	synonyms	"evasion by virus of host dendritic cell activity" RELATED [];"evasion by virus of host dendritic cell response" EXACT [];"impairing dendritic cell function by virus" EXACT [UniProtKB-KW:KW-1118];"modulation of host dendritic cell activity by virus" BROAD [UniProtKB-KW:KW-1118]	WAS	"evasion by virus of host dendritic cell response" EXACT [];"impairing dendritic cell function by virus" EXACT [UniProtKB-KW:KW-1118];"modulation of host dendritic cell activity by virus" BROAD [UniProtKB-KW:KW-1118]
biological_process	GO:0042199	cyanuric acid metabolic process
	definition	"The chemical reactions and pathways involving cyanuric acid, a suspected gastrointestinal or liver toxicant, and a potential degradation product of triazine herbicides, such as atrazine and simazine. It is widely used for the stabilization of available chlorine in swimming pool water and is also the starting compound for the synthesis of many organic derivatives." [GOC:curators]	WAS	"The chemical reactions and pathways involving cyanuric acid, a suspected gastrointestinal or liver toxicant, and a potential degradation product of triazine herbicides, such as atrazine and simazine. It is widely used for the stabilization of available chlorine in swimming pool water and is also the starting compound for the synthesis of many organic derivatives." [UM-BBD_pathwayID:cya]
biological_process	GO:0042201	N-cyclopropylmelamine metabolic process
	definition	"The chemical reactions and pathways involving N-cyclopropylmelamine, a triazine compound commonly used as an insect growth regulator insecticide." [GOC:curators]	WAS	"The chemical reactions and pathways involving N-cyclopropylmelamine, a triazine compound commonly used as an insect growth regulator insecticide." [UM-BBD_pathwayID:cpm]
biological_process	GO:0042203	toluene catabolic process
	definition	"The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products." [UM-BBD_pathwayID:tol]	WAS	"The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products." [GOC:go_curators]
biological_process	GO:0042212	cresol metabolic process
	definition	"The chemical reactions and pathways involving cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote." [GOC:curators]	WAS	"The chemical reactions and pathways involving cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote." [UM-BBD_pathwayID:mcr]
biological_process	GO:0042783	symbiont-mediated evasion of host immune response
	name	symbiont-mediated evasion of host immune response	WAS	evasion of host immune response
	synonyms	"active evasion of host immune response" RELATED [];"active evasion of immune response of other organism involved in symbiotic interaction" BROAD [];"active immune evasion" BROAD [];"evasion by virus of host immune response" RELATED [];"evasion of host immune response" EXACT [];"evasion or tolerance of host immune response" BROAD [];"immune evasion" EXACT [];"mitigation by virus of host immune response" RELATED [];"mitigation of host immune response" RELATED [];"mitigation of host immune response by virus" RELATED [];"passive evasion of host immune response" RELATED [];"passive evasion of immune response of other organism involved in symbiotic interaction" RELATED [];"passive immune evasion" RELATED [];"suppression by virus of host immune response" RELATED []	WAS	"active evasion of host immune response" RELATED [];"active evasion of immune response of other organism involved in symbiotic interaction" BROAD [];"active immune evasion" BROAD [];"evasion by virus of host immune response" RELATED [];"evasion or tolerance of host immune response" BROAD [];"immune evasion" EXACT [];"mitigation by virus of host immune response" RELATED [];"mitigation of host immune response" RELATED [];"mitigation of host immune response by virus" RELATED [];"passive evasion of host immune response" RELATED [];"passive evasion of immune response of other organism involved in symbiotic interaction" RELATED [];"passive immune evasion" RELATED [];"suppression by virus of host immune response" RELATED []
biological_process	GO:0042921	nuclear receptor-mediated glucocorticoid signaling pathway
	definition	"A nuclear receptor-mediated signaling pathway initiated by a glucocorticoid binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription." [PMID:15240347]	WAS	"A nuclear receptor-mediated signaling pathway initiated by a glucocorticoid binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription." [GOC:mah]
biological_process	GO:0043039	tRNA aminoacylation
	definition	"The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules." [GOC:ma, GOC:mah]	WAS	"The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules." [GOC:ma, GOC:mah, MetaCyc:Aminoacyl-tRNAs]
biological_process	GO:0043490	malate-aspartate shuttle
	definition	"The process of transferring reducing equivalents from NADH in the cytosol to the mitochondria via malate. Cytosolic aspartate aminotransferase converts aspartate to oxaloacetate, and cytosolic malate dehydrogenase uses NADH to convert oxaloacetate to malate in the cytosol; the malate-alpha-ketoglutarate carrier then transports the malate into the mitochondria where mitochondrial malate dehydrogenase uses NAD to convert malate back to oxaloacetate; the electrons on the reduced NADH are then available for use in the electron transport chain; mitochondrial aspartate aminotransferase converts oxaloacetate to aspartate, and the glutamate-aspartate carrier transports the aspartate back to the cytosol to complete the cycle." [GOC:sjm, PMID:16368075]	WAS	"The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesize malate in the cytosol; this compound is then transported into the mitochondria where it is converted to oxaloacetate using NADH, the oxaloacetate reacts with gluamate to form aspartate, and the aspartate then returns to the cytosol to complete the cycle." [GOC:jl, GOC:mtg_electron_transport, ISBN:0716743663]
biological_process	GO:0044865	symbiont-mediated suppression of host cell division
	name	symbiont-mediated suppression of host cell division	WAS	negative regulation by virus of host cell division
	definition	"A process in which a symbiont inhibits or disrupts the normal execution of cell division in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:24218612]	WAS	"Any process where an infecting virus stops, prevents, or reduces the frequency, rate or extent of its host's cell division." [GOC:jl]
	synonyms	"inhibition by virus of host cell division" NARROW [];"negative regulation by virus of host cell division" NARROW []	WAS	"inhibition by virus of host cell division" NARROW []
biological_process	GO:0046300	2,4-dichlorophenoxyacetic acid catabolic process
	definition	"The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds." [GOC:ai, UM-BBD_pathwayID:2\,4-d]	WAS	"The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds." [GOC:ai]
biological_process	GO:0046494	rhizobactin 1021 metabolic process
	definition	"The chemical reactions and pathways involving rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti." [PMID:11274118]	WAS	"The chemical reactions and pathways involving rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti." [MetaCyc:PWY-761, PMID:11274118]
biological_process	GO:0046499	S-adenosylmethioninamine metabolic process
	definition	"The chemical reactions and pathways involving S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt." [GOC:mah]	WAS	"The chemical reactions and pathways involving S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt." [GOC:mah, MetaCyc:S-ADENOSYLMETHIONINAMINE]
biological_process	GO:0046597	host-mediated suppression of symbiont invasion
	name	host-mediated suppression of symbiont invasion	WAS	negative regulation of viral entry into host cell
	definition	"A process in which a host inhibits or disrupts the entry of a symbiont into a host cell." [PMID:23544079]	WAS	"Any process that stops, prevents, or reduces the frequency, rate or extent of the entry of viral entry into a host cell." [GOC:jl]
	synonyms	"blocking of symbiont entry into host cell" EXACT [];"negative regulation of symbiont entry into host cell" RELATED [];"negative regulation of viral entry into host cell" NARROW [];"negative regulation of viral penetration into host cell" EXACT [];"prevention of symbiont entry into host cell" EXACT []	WAS	"negative regulation of viral penetration into host cell" EXACT []
biological_process	GO:0050652	dermatan sulfate proteoglycan biosynthetic process, chain elongation
	name	dermatan sulfate proteoglycan biosynthetic process, chain elongation	WAS	dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
	synonyms	"chondroitin sulfate B proteoglycan biosynthesis, polysaccharide chain biosynthesis" EXACT [];"chondroitin sulfate B proteoglycan biosynthesis, polysaccharide chain biosynthetic process" EXACT [];"chondroitin sulfate B proteoglycan chain elongation" EXACT [];"dermatan sulfate proteoglycan anabolism, polysaccharide chain anabolism" EXACT [];"dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process" EXACT [];"dermatan sulfate proteoglycan chain elongation" EXACT [];"dermatan sulfate proteoglycan formation, polysaccharide chain biosynthesis" EXACT [];"dermatan sulfate proteoglycan formation, polysaccharide chain formation" EXACT [];"dermatan sulfate proteoglycan synthesis, polysaccharide chain synthesis" EXACT [];"dermatan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis" EXACT [];"dermatan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process" EXACT []	WAS	"chondroitin sulfate B proteoglycan biosynthesis, polysaccharide chain biosynthesis" EXACT [];"chondroitin sulfate B proteoglycan biosynthesis, polysaccharide chain biosynthetic process" EXACT [];"chondroitin sulfate B proteoglycan chain elongation" EXACT [];"dermatan sulfate proteoglycan anabolism, polysaccharide chain anabolism" EXACT [];"dermatan sulfate proteoglycan chain elongation" EXACT [];"dermatan sulfate proteoglycan formation, polysaccharide chain biosynthesis" EXACT [];"dermatan sulfate proteoglycan formation, polysaccharide chain formation" EXACT [];"dermatan sulfate proteoglycan synthesis, polysaccharide chain synthesis" EXACT [];"dermatan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis" EXACT [];"dermatan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process" EXACT []
biological_process	GO:0050653	chondroitin sulfate proteoglycan biosynthetic process, chain elongation
	name	chondroitin sulfate proteoglycan biosynthetic process, chain elongation	WAS	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
	synonyms	"chondroitin sulfate proteoglycan anabolism, polysaccharide chain anabolism" EXACT [];"chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process" EXACT [];"chondroitin sulfate proteoglycan chain elongation" EXACT [];"chondroitin sulfate proteoglycan formation, polysaccharide chain biosynthesis" EXACT [];"chondroitin sulfate proteoglycan formation, polysaccharide chain formation" EXACT [];"chondroitin sulfate proteoglycan synthesis, polysaccharide chain synthesis" EXACT [];"chondroitin sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis" EXACT [];"chondroitin sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process" EXACT []	WAS	"chondroitin sulfate proteoglycan anabolism, polysaccharide chain anabolism" EXACT [];"chondroitin sulfate proteoglycan chain elongation" EXACT [];"chondroitin sulfate proteoglycan formation, polysaccharide chain biosynthesis" EXACT [];"chondroitin sulfate proteoglycan formation, polysaccharide chain formation" EXACT [];"chondroitin sulfate proteoglycan synthesis, polysaccharide chain synthesis" EXACT [];"chondroitin sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis" EXACT [];"chondroitin sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process" EXACT []
biological_process	GO:0050877	nervous system process
	definition	"An organ system process carried out by any of the organs or tissues of the neurological system." [GOC:ai, GOC:mtg_cardio]	WAS	"A organ system process carried out by any of the organs or tissues of neurological system." [GOC:ai, GOC:mtg_cardio]
biological_process	GO:0051504	diterpene phytoalexin precursor biosynthetic process
	name	diterpene phytoalexin precursor biosynthetic process	WAS	diterpene phytoalexin precursor biosynthetic process pathway
biological_process	GO:0051851	host-mediated perturbation of symbiont process
	name	host-mediated perturbation of symbiont process	WAS	modulation by host of symbiont process
	synonyms	"modification by host of symbiont morphology or physiology" RELATED [];"modulation by host of symbiont process" EXACT []	WAS	"modification by host of symbiont morphology or physiology" RELATED []
biological_process	GO:0052081	symbiont-mediated perturbation of host salicylic acid-mediated signal transduction pathway
	definition	"A process in which a symbiont alters or subverts a salicylic acid-mediated signal transduction pathway in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06, PMID:35698792]	WAS	"A process in which a symbiont alters or subverts a salicylic acid-mediated signal transduction pathway in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06]
biological_process	GO:0052084	symbiont-mediated modulation of host ethylene-mediated defense response
	name	symbiont-mediated modulation of host ethylene-mediated defense response	WAS	modulation by symbiont of host ethylene-mediated defense response
	synonyms	"modulation by organism of defense-related ethylene-mediated signal transduction pathway in other organism involved in symbiotic interaction" BROAD [];"modulation by organism of ethylene-mediated defense response of other organism involved in symbiotic interaction" BROAD [];"modulation by symbiont of defense-related host ethylene-mediated signal transduction pathway" BROAD [];"modulation by symbiont of host ethylene-mediated defense response" EXACT []	WAS	"modulation by organism of defense-related ethylene-mediated signal transduction pathway in other organism involved in symbiotic interaction" BROAD [];"modulation by organism of ethylene-mediated defense response of other organism involved in symbiotic interaction" BROAD [];"modulation by symbiont of defense-related host ethylene-mediated signal transduction pathway" BROAD []
biological_process	GO:0052088	symbiont-mediated perturbation of host jasmonic acid signaling
	name	symbiont-mediated perturbation of host jasmonic acid signaling	WAS	symbiont defense to host-produced jasmonic acid
	definition	"A process in which a symbiont alters or subverts a jasmonic acid-mediated signal transduction pathway in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06, PMID:29222513, PMID:35698792]	WAS	"Any process in which a symbiont modulates the frequency, rate or extent of the jasmonic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06]
	synonyms	"activation by organism of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"activation by organism of defense-related host SA-mediated signal transduction pathway" NARROW [];"activation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"down regulation by symbiont of host jasmonic acid-mediated defense response" NARROW [];"down-regulation by symbiont of host jasmonic acid-mediated defense response" NARROW [];"downregulation by symbiont of host jasmonic acid-mediated defense response" NARROW [];"induction by organism of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"induction by organism of defense-related host SA-mediated signal transduction pathway" NARROW [];"induction by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"inhibition by symbiont of host jasmonic acid-mediated defense response" NARROW [];"modulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction" NARROW [];"modulation by organism of host JA-mediated defense response" NARROW [];"modulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction" NARROW [];"modulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"negative regulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction" NARROW [];"negative regulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction" NARROW [];"negative regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"negative regulation by symbiont of host jasmonic acid-mediated defense response" NARROW [];"positive regulation by organism of defense-related host SA-mediated signal transduction pathway" NARROW [];"positive regulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction" NARROW [];"positive regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"stimulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"suppression by organism of host JA-mediated defense response" EXACT [];"suppression by symbiont of host jasmonic acid-mediated defense response" RELATED [];"symbiont defense to host-produced jasmonic acid" EXACT [];"up regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"up-regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"upregulation by organism of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"upregulation by organism of defense-related host SA-mediated signal transduction pathway" NARROW [];"upregulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW []	WAS	"activation by organism of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"activation by organism of defense-related host SA-mediated signal transduction pathway" NARROW [];"activation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"down regulation by symbiont of host jasmonic acid-mediated defense response" NARROW [];"down-regulation by symbiont of host jasmonic acid-mediated defense response" NARROW [];"downregulation by symbiont of host jasmonic acid-mediated defense response" NARROW [];"induction by organism of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"induction by organism of defense-related host SA-mediated signal transduction pathway" NARROW [];"induction by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"inhibition by symbiont of host jasmonic acid-mediated defense response" NARROW [];"modulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction" NARROW [];"modulation by organism of host JA-mediated defense response" NARROW [];"modulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction" NARROW [];"modulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"negative regulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction" NARROW [];"negative regulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction" NARROW [];"negative regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"negative regulation by symbiont of host jasmonic acid-mediated defense response" NARROW [];"positive regulation by organism of defense-related host SA-mediated signal transduction pathway" NARROW [];"positive regulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction" NARROW [];"positive regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"stimulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"suppression by organism of host JA-mediated defense response" EXACT [];"suppression by symbiont of host jasmonic acid-mediated defense response" RELATED [];"up regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"up-regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"upregulation by organism of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW [];"upregulation by organism of defense-related host SA-mediated signal transduction pathway" NARROW [];"upregulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway" NARROW []
biological_process	GO:0052151	symbiont-mediated activation of host apoptosis
	definition	"A process in which a symbiont initiates, promotes, or enhances the normal execution of host apoptosis, leading to an increase in the frequency, rate or extent of apoptosis in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:11805081, PMID:18037263, PMID:19801898, PMID:29571981]	WAS	"A process in which a symbiont gene product activates host apoptosis, leading to an increase in the frequency, rate or extent of apoptosis in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:11805081, PMID:18037263, PMID:19801898, PMID:29571981]
biological_process	GO:0052158	symbiont-mediated perturbation of host resistance gene-dependent defense response
	name	symbiont-mediated perturbation of host resistance gene-dependent defense response	WAS	modulation by symbiont of host resistance gene-dependent defense response
	synonyms	"modulation by organism of defense response in host by specific elicitors" EXACT [];"modulation by organism of host gene-for-gene resistance" EXACT [];"modulation by organism of pathogen-race/host plant cultivar-specific resistance in symbiont" EXACT [];"modulation by organism of resistance gene-dependent defense response of other organism involved in symbiotic interaction" BROAD [];"modulation by symbiont of host resistance gene-dependent defense response" EXACT []	WAS	"modulation by organism of defense response in host by specific elicitors" EXACT [];"modulation by organism of host gene-for-gene resistance" EXACT [];"modulation by organism of pathogen-race/host plant cultivar-specific resistance in symbiont" EXACT [];"modulation by organism of resistance gene-dependent defense response of other organism involved in symbiotic interaction" BROAD []
biological_process	GO:0052165	symbiont-mediated perturbation of host phytoalexin production
	name	symbiont-mediated perturbation of host phytoalexin production	WAS	symbiont defense to host-produced phytoalexin
	definition	"Any process in which a symbiont modulates the frequency, rate or extent of production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06, PMID:6870275]	WAS	"Any process in which a symbiont modulates the frequency, rate or extent of production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:mtg_pamgo_17jul06]
	synonyms	"evasion or tolerance by symbiont of host-produced phytoalexins" EXACT [];"evasion or tolerance of phytoalexins" EXACT [];"evasion or tolerance of phytoalexins produced by host in response to organism" EXACT [];"host phytoalexin detoxification" NARROW [];"modulation by organism of phytoalexin production in other organism involved in symbiotic interaction" NARROW [];"modulation by symbiont of host phytoalexin production" NARROW [];"phytoalexin detoxification" NARROW [];"response to host phytoalexin production" BROAD [];"response to phytoalexin production by other organism involved in symbiotic interaction" BROAD [];"symbiont defense to host-produced phytoalexin" EXACT []	WAS	"evasion or tolerance by symbiont of host-produced phytoalexins" EXACT [];"evasion or tolerance of phytoalexins" EXACT [];"evasion or tolerance of phytoalexins produced by host in response to organism" EXACT [];"host phytoalexin detoxification" NARROW [];"modulation by organism of phytoalexin production in other organism involved in symbiotic interaction" NARROW [];"modulation by symbiont of host phytoalexin production" NARROW [];"phytoalexin detoxification" NARROW [];"response to host phytoalexin production" BROAD [];"response to phytoalexin production by other organism involved in symbiotic interaction" BROAD []
biological_process	GO:0052200	symbiont-mediated response to host defenses
	name	symbiont-mediated response to host defenses	WAS	response to host defenses
	synonyms	"maintenance of symbiont tolerance to host defense molecules" NARROW [];"response of symbiont to host defense molecules" NARROW [];"response to host defense molecules" NARROW [];"response to host defenses" EXACT []	WAS	"maintenance of symbiont tolerance to host defense molecules" NARROW [];"response of symbiont to host defense molecules" NARROW [];"response to host defense molecules" NARROW []
biological_process	GO:0052315	phytoalexin biosynthetic process
	definition	"The chemical reactions and pathways resulting in the formation of phytoalexins, any of a range of substances produced by plants as part of their defense response." [PMID:22209038, PMID:3882051, Wikipedia:Phytoalexin]	WAS	"The chemical reactions and pathways resulting in the formation of phytoalexins, any of a range of substances produced by plants as part of their defense response." [Wikipedia:Phytoalexin]
biological_process	GO:0052776	chitin catabolic process to fructose 6-phosphate via glucosamine
	name	chitin catabolic process to fructose 6-phosphate via glucosamine	WAS	diacetylchitobiose catabolic process to glucosamine and acetate
	definition	"The pathway resulting in the breakdown of chitin into fructose 6-phosphate, via glucosamine; acetate is also produced during the process." [GOC:bf, GOC:mengo_curators, MetaCyc:PWY-6855, PMID:15136574, PMID:16232910, PMID:16736587]	WAS	"The pathway resulting in the breakdown of diacetylchitobiose into simpler products, including glucosamine and glucosamine. The catabolism proceeds by the deacetylation of diacetylchitobiose, producing acetate and GlcN-GlcNAc; the latter is cleaved to produce glucosamine (GlcN) and N-acetylglucosamine (GlcNAc). The N-acetylglucosamine (GlcNAc) is then deacetylated to produce glucosamine (GlcN) and acetate." [GOC:bf, GOC:mengo_curators, MetaCyc:PWY-6855, PMID:15136574, PMID:16232910, PMID:16736587]
	synonyms	"diacetylchitobiose catabolic process to glucosamine and acetate" EXACT []	WAS	N/A
biological_process	GO:0061007	hepaticobiliary system process
	definition	"A system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins." [GOC:dph]	WAS	"An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins." [GOC:dph]
biological_process	GO:0061681	Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate
	definition	"The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde-3-phosphate." [GOC:dph, PMID:12921536]	WAS	"The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde-3-phosphate." [GOC:dph, MetaCyc:ENTNER-DOUFDOROFF-PWY-III, PMID:12921536]
biological_process	GO:0061729	GDP-D-mannose biosynthetic process from fructose-6-phosphate
	name	GDP-D-mannose biosynthetic process from fructose-6-phosphate	WAS	GDP-mannose biosynthetic process from fructose-6-phosphate
	definition	"The chemical reactions and pathways resulting in the formation of GDP-D-mannose from D-fructose-6-phosphate." [GOC:dph, PMID:16339137]	WAS	"The chemical reactions and pathways resulting in the formation of GDP-mannose from fructose-6-phosphate." [GOC:dph, PMID:16339137]
	synonyms	"GDP-mannose biosynthetic process from fructose-6-phosphate" RELATED [];"GDP-mannose biosynthetic process from glucose" RELATED []	WAS	N/A
biological_process	GO:0090357	regulation of L-tryptophan metabolic process
	name	regulation of L-tryptophan metabolic process	WAS	regulation of tryptophan metabolic process
	synonyms	"regulation of tryptophan metabolic process" RELATED [];"regulation of tryptophan metabolism" EXACT [GOC:tb]	WAS	"regulation of tryptophan metabolism" EXACT [GOC:tb]
biological_process	GO:0090358	positive regulation of L-tryptophan metabolic process
	name	positive regulation of L-tryptophan metabolic process	WAS	positive regulation of tryptophan metabolic process
	synonyms	"positive regulation of tryptophan metabolic process" RELATED [];"positive regulation of tryptophan metabolism" EXACT [GOC:tb]	WAS	"positive regulation of tryptophan metabolism" EXACT [GOC:tb]
biological_process	GO:0090399	replicative senescence
	definition	"The process by which normal somatic cells reach an irreversible stage of cell cycle arrest following multiple rounds of replication; this end stage is associated with marked changes in gene expression and function. This is a natural barrier to unlimited proliferation of somatic cells, and is believed to be contolled by telomere shortening." [PMID:17014937, PMID:23061726]	WAS	"A cell aging process associated with the dismantling of a cell as a response to telomere shortening and/or cellular aging." [GOC:BHF]
biological_process	GO:0097250	mitochondrial respirasome assembly
	definition	"The aggregation, arrangement and bonding together of respiratory enzyme complexes I, III and IV of the mitochondrial inner membrane to form a large supercomplex." [PMID:30030361, PMID:32311046]	WAS	"The aggregation, arrangement and bonding together of a set of respiratory enzyme complexes of the mitochondrial inner membrane (including, for example, complex II, complex III, complex IV) to form a large supercomplex." [GOC:mcc, PMID:21909073, PMID:22342701]
biological_process	GO:0097294	'de novo' XMP biosynthetic process
	definition	"The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate, from simpler precursors." [GOC:yaf, PMID:27590927]	WAS	"The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate, from simpler precursors." [GOC:yaf, MetaCyc:IMP-DEHYDROG-RXN, PMID:27590927]
biological_process	GO:0140415	effector-mediated perturbation of host defenses by symbiont
	name	effector-mediated perturbation of host defenses by symbiont	WAS	effector-mediated modulation of host defenses by symbiont
	synonyms	"effector-mediated modulation of host defenses by symbiont" EXACT []	WAS	N/A
biological_process	GO:0140418	effector-mediated perturbation of host process by symbiont
	name	effector-mediated perturbation of host process by symbiont	WAS	effector-mediated modulation of host process by symbiont
	synonyms	"effector mediated modulation of host process by symbiont" EXACT [];"effector triggered modulation of host process by symbiont" EXACT [];"effector-dependent modulation of host process by symbiont" EXACT [];"effector-mediated modulation of host process by symbiont" EXACT []	WAS	"effector mediated modulation of host process by symbiont" EXACT [];"effector triggered modulation of host process by symbiont" EXACT [];"effector-dependent modulation of host process by symbiont" EXACT []
biological_process	GO:0140645	neutrophil extracellular trap formation
	name	neutrophil extracellular trap formation	WAS	neutrophic extracellular trap formation
biological_process	GO:0140883	symbiont-mediated activation of host reticulophagy
	name	symbiont-mediated activation of host reticulophagy	WAS	induction by virus of host reticulophagy
	definition	"A process in which a symbiont initiates, promotes, or enhances the normal execution of host reticulophagy, leading to an increase in the frequency, rate or extent of reticulophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:35239449]	WAS	"Any process in which a virus activates or increases the frequency, rate or extent of reticulophagy in the host." [PMID:35239449]
	synonyms	"activation of host reticulophagy by virus" EXACT [];"induction by virus of host reticulophagy" NARROW [];"positive regulation by virus of host reticulophagy" BROAD []	WAS	"activation of host reticulophagy by virus" EXACT [];"positive regulation by virus of host reticulophagy" BROAD []
biological_process	GO:0140976	host defense response against symbiont-mediated perturbation of plasma membrane integrity
	name	host defense response against symbiont-mediated perturbation of plasma membrane integrity	WAS	defense response against perturbation of plasma membrane integrity
	synonyms	"defense response against disruption of plasma membrane integrity" EXACT [];"defense response against perturbation of plasma membrane integrity" RELATED []	WAS	"defense response against disruption of plasma membrane integrity" EXACT []
biological_process	GO:0141154	symbiont-mediated suppression of host-directed shutoff of host translation
	definition	"A process in which a symbiont inhibits or disrupts the host shutoff of host translation, a host response that prevents mRNA in the cell to be translated, to prevent the symbiont from expressing its genes. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:20563710, PMID:21622569]	WAS	"A process in which a symbiont inhibits or disrupts the host shutoff of host translation, a host response that prevents mRNA in the cell to be translated, to prevent the symbiont from expressing its genes. The host is defined as the larger of the organisms involved in a symbiotic interaction." [GOC:pg]
biological_process	GO:0160164	negative regulation of chromatin looping
	name	negative regulation of chromatin looping	WAS	negative regulation of chromatin loopin
biological_process	GO:1901790	3-(2,3-dihydroxyphenyl)propanoate metabolic process
	definition	"The chemical reactions and pathways involving 3-(2,3-dihydroxyphenyl)propanoate." [GOC:TermGenie, GOC:yaf]	WAS	"The chemical reactions and pathways involving 3-(2,3-dihydroxyphenyl)propanoate." [GOC:TermGenie, GOC:yaf, MetaCyc:HCAMHPDEG-PWY]
biological_process	GO:1901807	capsanthin metabolic process
	definition	"The chemical reactions and pathways involving capsanthin." [GOC:TermGenie, GOC:yaf, PMID:10995282, UniPathway:UPA00806]	WAS	"The chemical reactions and pathways involving capsanthin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5174, PMID:10995282, UniPathway:UPA00806]
biological_process	GO:1901808	capsanthin catabolic process
	definition	"The chemical reactions and pathways resulting in the breakdown of capsanthin." [GOC:TermGenie, GOC:yaf, PMID:10995282, UniPathway:UPA00806]	WAS	"The chemical reactions and pathways resulting in the breakdown of capsanthin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5174, PMID:10995282, UniPathway:UPA00806]
biological_process	GO:1901824	alpha-carotene biosynthetic process
	name	alpha-carotene biosynthetic process	WAS	delta-carotene biosynthetic process
	definition	"The chemical reactions and pathways resulting in the formation of alpha-carotene." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5946, PMID:8837512, UniPathway:UPA00801]	WAS	"The chemical reactions and pathways resulting in the formation of delta-carotene." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5946, PMID:8837512, UniPathway:UPA00801]
	synonyms	"delta-carotene anabolism" EXACT [GOC:TermGenie];"delta-carotene biosynthesis" EXACT [GOC:TermGenie];"delta-carotene biosynthetic process" EXACT [];"delta-carotene formation" EXACT [GOC:TermGenie];"delta-carotene synthesis" EXACT [GOC:TermGenie]	WAS	"delta-carotene anabolism" EXACT [GOC:TermGenie];"delta-carotene biosynthesis" EXACT [GOC:TermGenie];"delta-carotene formation" EXACT [GOC:TermGenie];"delta-carotene synthesis" EXACT [GOC:TermGenie]
biological_process	GO:1901833	neoxanthin biosynthetic process
	name	neoxanthin biosynthetic process	WAS	all-trans-neoxanthin biosynthetic process
	definition	"The chemical reactions and pathways resulting in the formation of trans-neoxanthin and 9'-cis-neoxanthin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-6809, PMID:11029576, UniPathway:UPA00388]	WAS	"The chemical reactions and pathways resulting in the formation of all-trans-neoxanthin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-6809, PMID:11029576, UniPathway:UPA00388]
	synonyms	"all-trans-neoxanthin anabolism" EXACT [GOC:TermGenie];"all-trans-neoxanthin biosynthesis" EXACT [GOC:TermGenie];"all-trans-neoxanthin biosynthetic process" NARROW [];"all-trans-neoxanthin formation" EXACT [GOC:TermGenie];"all-trans-neoxanthin synthesis" EXACT [GOC:TermGenie];"neoxanthin anabolism" EXACT [GOC:yaf];"neoxanthin biosynthesis" EXACT [GOC:yaf];"neoxanthin formation" EXACT [GOC:yaf];"neoxanthin synthesis" EXACT [GOC:yaf]	WAS	"all-trans-neoxanthin anabolism" EXACT [GOC:TermGenie];"all-trans-neoxanthin biosynthesis" EXACT [GOC:TermGenie];"all-trans-neoxanthin formation" EXACT [GOC:TermGenie];"all-trans-neoxanthin synthesis" EXACT [GOC:TermGenie];"neoxanthin anabolism" EXACT [GOC:yaf];"neoxanthin biosynthesis" EXACT [GOC:yaf];"neoxanthin biosynthetic process" EXACT [GOC:yaf];"neoxanthin formation" EXACT [GOC:yaf];"neoxanthin synthesis" EXACT [GOC:yaf]
biological_process	GO:1901864	capsorubin metabolic process
	definition	"The chemical reactions and pathways involving capsorubin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00807]	WAS	"The chemical reactions and pathways involving capsorubin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5174, UniPathway:UPA00807]
biological_process	GO:1901865	capsorubin catabolic process
	definition	"The chemical reactions and pathways resulting in the breakdown of capsorubin." [GOC:TermGenie, GOC:yaf, UniPathway:UPA00807]	WAS	"The chemical reactions and pathways resulting in the breakdown of capsorubin." [GOC:TermGenie, GOC:yaf, MetaCyc:PWY-5174, UniPathway:UPA00807]
biological_process	GO:1902616	O-acyl-L-carnitine transmembrane transport
	name	O-acyl-L-carnitine transmembrane transport	WAS	acyl carnitine transmembrane transport
	definition	"The process in which O-acyl-L-carnitine is transported across a membrane." [GO_REF:0000069, GOC:pr, GOC:TermGenie]	WAS	"The process in which acyl carnitine is transported across a membrane." [GO_REF:0000069, GOC:pr, GOC:TermGenie]
biological_process	GO:1904916	L-lysine transmembrane transport from lysosomal lumen to cytosol
	name	L-lysine transmembrane transport from lysosomal lumen to cytosol	WAS	transmembrane L-lysine transport from lysosomal lumen to cytosol
	synonyms	"transmembrane L-lysine transport from lysosomal lumen to cytosol" EXACT []	WAS	N/A
biological_process	GO:1904918	L-histidine transmembrane transport from lysosomal lumen to cytosol
	name	L-histidine transmembrane transport from lysosomal lumen to cytosol	WAS	transmembrane L-histidine transport from lysosomal lumen to cytosol
	synonyms	"transmembrane L-histidine transport from lysosomal lumen to cytosol" EXACT []	WAS	N/A
biological_process	GO:1904919	L-cystine transmembrane transport from lysosomal lumen to cytosol
	name	L-cystine transmembrane transport from lysosomal lumen to cytosol	WAS	transmembrane L-cystine transport from lysosomal lumen to cytosol
	synonyms	"transmembrane L-cystine transport from lysosomal lumen to cytosol" EXACT []	WAS	N/A
biological_process	GO:1905554	negative regulation of blood vessel branching
	name	negative regulation of blood vessel branching	WAS	negative regulation of vessel branching
biological_process	GO:1990217	symbiont-mediated suppression of host phytoalexin production
	name	symbiont-mediated suppression of host phytoalexin production	WAS	suppression by symbiont of host phytoalexin production
	definition	"A process in which a symbiont inhibits or disrupts the production of phytoalexins in the host organism. Phytoalexins are produced by plants to fight against pathogens. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:21402357]	WAS	"Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of phytoalexin production in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." [PMID:21402357]
	synonyms	"negative regulation by symbiont of host phytoalexin production" EXACT [];"suppression by symbiont of host phytoalexin production" EXACT []	WAS	"negative regulation by symbiont of host phytoalexin production" EXACT []
biological_process	GO:2000322	regulation of nuclear receptor-mediated glucocorticoid signaling pathway
	name	regulation of nuclear receptor-mediated glucocorticoid signaling pathway	WAS	regulation of glucocorticoid receptor signaling pathway
	definition	"Any process that modulates the frequency, rate or extent of nuclear receptor-mediated glucocorticoid signaling pathway." [GOC:BHF]	WAS	"Any process that modulates the frequency, rate or extent of glucocorticoid receptor signaling pathway." [GOC:BHF]
	synonyms	"regulation of glucocorticoid receptor signaling pathway" EXACT [];"regulation of glucocorticoid receptor signalling pathway" EXACT [GOC:obol]	WAS	"regulation of glucocorticoid receptor signalling pathway" EXACT [GOC:obol]
biological_process	GO:2000323	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
	name	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway	WAS	negative regulation of glucocorticoid receptor signaling pathway
	definition	"Any process that stops, prevents or reduces the frequency, rate or extent of nuclear receptor-mediated glucocorticoid signaling pathway." [GOC:BHF]	WAS	"Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid receptor signaling pathway." [GOC:BHF]
	synonyms	"negative regulation of glucocorticoid receptor signaling pathway" EXACT [];"negative regulation of glucocorticoid receptor signalling pathway" EXACT [GOC:obol]	WAS	"negative regulation of glucocorticoid receptor signalling pathway" EXACT [GOC:obol]
biological_process	GO:2000324	positive regulation of nuclear receptor-mediated glucocorticoid signaling pathway
	name	positive regulation of nuclear receptor-mediated glucocorticoid signaling pathway	WAS	positive regulation of glucocorticoid receptor signaling pathway
	definition	"Any process that activates or increases the frequency, rate or extent of nuclear receptor-mediated glucocorticoid signaling pathway." [GOC:BHF]	WAS	"Any process that activates or increases the frequency, rate or extent of glucocorticoid receptor signaling pathway." [GOC:BHF]
	synonyms	"positive regulation of glucocorticoid receptor signaling pathway" EXACT [];"positive regulation of glucocorticoid receptor signalling pathway" EXACT [GOC:obol]	WAS	"positive regulation of glucocorticoid receptor signalling pathway" EXACT [GOC:obol]
molecular_function	GO:0000246	Delta24(24-1) sterol reductase activity
	name	Delta24(24-1) sterol reductase activity	WAS	delta24(24-1) sterol reductase activity
molecular_function	GO:0000252	3-beta-hydroxysteroid dehydrogenase [NAD(P)+]/C4-decarboxylase activity
	name	3-beta-hydroxysteroid dehydrogenase [NAD(P)+]/C4-decarboxylase activity	WAS	C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
	comment	N/A	WAS	Note that zymosterol is cholesta-8,24-dien-3-ol.
	synonyms	"3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)" RELATED [EC:1.1.1.170];"3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate:NAD(P)+ 3-oxidoreductase (decarboxylating)" EXACT [];"3beta-hydroxy-4beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)" RELATED [];"3beta-hydroxy-4beta-methylcholestenoate dehydrogenase activity" RELATED [];"C-3 sterol dehydrogenase (C-4 decarboxylase) activity" RELATED [];"C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity" EXACT [];"C-3 sterol dehydrogenase activity" RELATED [];"sterol 4alpha-carboxylic decarboxylase activity" RELATED [];"sterol-4-carboxylate 3-dehydrogenase (decarboxylating) activity" RELATED [];"sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating)" RELATED []	WAS	"3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)" RELATED [EC:1.1.1.170];"3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate:NAD(P)+ 3-oxidoreductase (decarboxylating)" EXACT [];"3beta-hydroxy-4beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)" RELATED [];"3beta-hydroxy-4beta-methylcholestenoate dehydrogenase activity" RELATED [];"C-3 sterol dehydrogenase (C-4 decarboxylase) activity" RELATED [];"C-3 sterol dehydrogenase activity" RELATED [];"sterol 4alpha-carboxylic decarboxylase activity" RELATED [];"sterol-4-carboxylate 3-dehydrogenase (decarboxylating) activity" RELATED [];"sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating)" RELATED []
molecular_function	GO:0000253	3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity
	name	3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity	WAS	3-keto sterol reductase activity
	comment	N/A	WAS	Note that zymosterol is cholesta-8,24-dien-3-ol.
	synonyms	"3-keto sterol reductase activity" EXACT [];"3-keto-steroid reductase activity" EXACT [];"3-KSR activity" RELATED [EC:1.1.1.270];"3beta-hydroxy-steroid:NADP+ 3-oxidoreductase" RELATED [EC:1.1.1.270]	WAS	"3-keto-steroid reductase activity" EXACT [];"3-KSR activity" RELATED [EC:1.1.1.270];"3beta-hydroxy-steroid:NADP+ 3-oxidoreductase" RELATED [EC:1.1.1.270]
molecular_function	GO:0000254	C-4 methylsterol oxidase activity
	comment	N/A	WAS	Note that zymosterol is cholesta-8,24-dien-3-ol.
molecular_function	GO:0001537	dermatan 4-sulfotransferase activity
	name	dermatan 4-sulfotransferase activity	WAS	dermatan 4-sulfotransferase
molecular_function	GO:0003707	nuclear steroid receptor activity
	definition	"A nuclear receptor activity regulated by steroid binding and modulating the transcription of specific gene sets transcribed by RNA polymerase II." [GOC:signaling, PMID:14708019]	WAS	"Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function." [GOC:signaling, PMID:14708019]
molecular_function	GO:0003854	3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity
	name	3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity	WAS	3-beta-hydroxy-delta5-steroid dehydrogenase (NAD+) activity
molecular_function	GO:0004111	creatine kinase activity
	comment	Note that this term has a MetaCyc pathway reference as the pathway only has a single step.	WAS	N/A
molecular_function	GO:0004161	dimethylallyltranstransferase activity
	synonyms	"(2E,6E)-farnesyl diphosphate synthetase activity" RELATED [EC:2.5.1.1];"dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase activity" RELATED [EC:2.5.1.1];"dimethylallyltransferase activity" EXACT [];"diprenyltransferase activity" RELATED [EC:2.5.1.1];"DMAPP:IPP-dimethylallyltransferase activity" RELATED [EC:2.5.1.1];"geranyl diphosphate synthase activity" EXACT [];"geranyl pyrophosphate synthase activity" RELATED [EC:2.5.1.1];"geranyl pyrophosphate synthetase activity" RELATED [EC:2.5.1.1];"geranyl-diphosphate synthase activity" RELATED [EC:2.5.1.1];"trans-farnesyl pyrophosphate synthetase activity" RELATED [EC:2.5.1.1]	WAS	"(2E,6E)-farnesyl diphosphate synthetase activity" RELATED [EC:2.5.1.1];"dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase activity" RELATED [EC:2.5.1.1];"dimethylallyltransferase activity" EXACT [];"diprenyltransferase activity" RELATED [EC:2.5.1.1];"DMAPP:IPP-dimethylallyltransferase activity" RELATED [EC:2.5.1.1];"geranyl diphosphate synthase" EXACT [];"geranyl pyrophosphate synthase activity" RELATED [EC:2.5.1.1];"geranyl pyrophosphate synthetase activity" RELATED [EC:2.5.1.1];"geranyl-diphosphate synthase activity" RELATED [EC:2.5.1.1];"trans-farnesyl pyrophosphate synthetase activity" RELATED [EC:2.5.1.1]
molecular_function	GO:0004177	aminopeptidase activity
	definition	"Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain." [EC:3.4.11.-, https://www.ebi.ac.uk/merops/about/glossary.shtml#AMINOPEPTIDASE, PMID:24157837]	WAS	"Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain." [https://www.ebi.ac.uk/merops/about/glossary.shtml#AMINOPEPTIDASE, PMID:24157837]
molecular_function	GO:0004230	glutamyl aminopeptidase activity
	is_obsolete	False	WAS	True
	name	glutamyl aminopeptidase activity	WAS	obsolete glutamyl aminopeptidase activity
	definition	"Catalysis of the release of a N-terminal glutamate (and to a lesser extent aspartate) from a peptide." [EC:3.4.11.7]	WAS	"OBSOLETE. Catalysis of the release of a N-terminal glutamate (and to a lesser extent aspartate) from a peptide." [EC:3.4.11.7]
	comment	N/A	WAS	This term was made obsolete because it represents a gene product.
	synonyms	"aminopeptidase A" RELATED [EC:3.4.11.7];"angiotensinase A" RELATED [EC:3.4.11.7];"angiotensinase A2" RELATED [EC:3.4.11.7];"antigen BP-1/6C3 of mouse B lymphocytes" RELATED [EC:3.4.11.7];"aspartate aminopeptidase activity" RELATED [EC:3.4.11.7];"Ca2+-activated glutamate aminopeptidase activity" RELATED [EC:3.4.11.7];"glutamyl peptidase activity" RELATED [EC:3.4.11.7];"L-aspartate aminopeptidase activity" RELATED [EC:3.4.11.7];"membrane aminopeptidase II" RELATED [EC:3.4.11.7]	WAS	"aminopeptidase A" RELATED [EC:3.4.11.7];"angiotensinase A" RELATED [EC:3.4.11.7];"angiotensinase A2" RELATED [EC:3.4.11.7];"antigen BP-1/6C3 of mouse B lymphocytes" RELATED [EC:3.4.11.7];"aspartate aminopeptidase activity" RELATED [EC:3.4.11.7];"Ca2+-activated glutamate aminopeptidase activity" RELATED [EC:3.4.11.7];"glutamyl aminopeptidase activity" EXACT [];"glutamyl peptidase activity" RELATED [EC:3.4.11.7];"L-aspartate aminopeptidase activity" RELATED [EC:3.4.11.7];"membrane aminopeptidase II" RELATED [EC:3.4.11.7]
molecular_function	GO:0004311	geranylgeranyl diphosphate synthase activity
	name	geranylgeranyl diphosphate synthase activity	WAS	farnesyltranstransferase activity
	synonyms	"farnesyltranstransferase activity" EXACT [EC:2.5.1.29];"geranylgeranyl pyrophosphate synthase activity" EXACT [EC:2.5.1.29];"geranylgeranyl pyrophosphate synthetase activity" EXACT [EC:2.5.1.29];"geranylgeranyl-diphosphate synthase activity" EXACT [EC:2.5.1.29];"geranylgeranyl-PP synthetase activity" EXACT [EC:2.5.1.29];"trans,trans-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase activity" RELATED [EC:2.5.1.29]	WAS	"geranylgeranyl pyrophosphate synthase activity" EXACT [EC:2.5.1.29];"geranylgeranyl pyrophosphate synthetase activity" EXACT [EC:2.5.1.29];"geranylgeranyl-diphosphate synthase activity" EXACT [EC:2.5.1.29];"geranylgeranyl-PP synthetase activity" EXACT [EC:2.5.1.29];"trans,trans-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase activity" RELATED [EC:2.5.1.29]
molecular_function	GO:0004337	(2E,6E)-farnesyl diphosphate synthase activity
	name	(2E,6E)-farnesyl diphosphate synthase activity	WAS	geranyltranstransferase activity
	synonyms	"farnesyl diphosphate synthase activity" EXACT [];"farnesyl diphosphate synthetase activity" RELATED [EC:2.5.1.10];"farnesyl pyrophosphate synthetase activity" EXACT [];"farnesyl-diphosphate synthase activity" EXACT [];"farnesylpyrophosphate synthetase activity" RELATED [EC:2.5.1.10];"FPP synthetase activity" RELATED [EC:2.5.1.10];"geranyl transferase I" RELATED [EC:2.5.1.10];"geranyl-diphosphate:isopentenyl-diphosphate geranyltranstransferase activity" RELATED [EC:2.5.1.10];"geranyltransferase activity" RELATED [EC:2.5.1.10];"geranyltranstransferase activity" EXACT [EC:2.5.1.10]	WAS	"farnesyl diphosphate synthetase activity" RELATED [EC:2.5.1.10];"farnesyl pyrophosphate synthetase activity" EXACT [];"farnesyl-diphosphate synthase activity" EXACT [];"farnesylpyrophosphate synthetase activity" RELATED [EC:2.5.1.10];"FPP synthetase activity" RELATED [EC:2.5.1.10];"geranyl transferase I" RELATED [EC:2.5.1.10];"geranyl-diphosphate:isopentenyl-diphosphate geranyltranstransferase activity" RELATED [EC:2.5.1.10];"geranyltransferase activity" RELATED [EC:2.5.1.10]
molecular_function	GO:0004394	heparan sulfate 2-sulfotransferase activity
	name	heparan sulfate 2-sulfotransferase activity	WAS	heparan sulfate 2-O-sulfotransferase activity
	synonyms	"heparan sulfate 2-O-sulfotransferase activity" EXACT [];"heparan-sulfate 2-O-sulphotransferase activity" EXACT [];"heparin 2-sulfotransferase activity" RELATED [];"heparin-sulphate 2-sulphotransferase activity" RELATED []	WAS	"heparan-sulfate 2-O-sulphotransferase activity" EXACT [];"heparin 2-sulfotransferase activity" RELATED [];"heparin-sulphate 2-sulphotransferase activity" RELATED []
molecular_function	GO:0004619	phosphoglycerate mutase activity
	synonyms	"2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity" NARROW [];"2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity" NARROW [];"D-phosphoglycerate 2,3-phosphomutase activity" RELATED [];"PGA mutase activity" RELATED [];"PGAM activity" RELATED [];"PGM" EXACT [];"phosphoglycerate phosphomutase activity" RELATED [];"phosphoglyceromutase activity" RELATED []	WAS	"D-phosphoglycerate 2,3-phosphomutase activity" RELATED [];"PGA mutase activity" RELATED [];"PGAM activity" RELATED [];"PGM" EXACT [];"phosphoglycerate phosphomutase activity" RELATED [];"phosphoglyceromutase activity" RELATED []
molecular_function	GO:0004769	steroid Delta-isomerase activity
	name	steroid Delta-isomerase activity	WAS	steroid delta-isomerase activity
molecular_function	GO:0004779	sulfate adenylyltransferase activity
	definition	"Catalysis of the transfer of an adenylyl group from an adenosine nucleotide (ATP or ADP) to sulfate, forming adenylylsulfate." [GOC:mah]	WAS	"Catalysis of the transfer of an adenylyl group from an adenosine nucleotide (ATP or ADP) to sulfate, forming adenylylsulfate." [GOC:mah, MetaCyc:SULFATE-ADENYLYLTRANS-RXN, MetaCyc:SULFATE-ADENYLYLTRANSFERASE-ADP-RXN]
molecular_function	GO:0004883	nuclear glucocorticoid receptor activity
	definition	"A nuclear receptor activity regulated by glucocorticoid binding and modulating the transcription of specific gene sets transcribed by RNA polymerase II." [GOC:signaling, PMID:17689856, PMID:20920967]	WAS	"Combining with a glucocorticoid and transmitting the signal within the cell trigger a change in cell activity or function." [GOC:signaling, PMID:17689856, PMID:20920967]
molecular_function	GO:0005125	cytokine activity
	synonyms	"autocrine activity" RELATED [GOC:rl];"paracrine activity" RELATED [GOC:rl];"phytocytokine activity" NARROW [PMID:23072994]	WAS	"autocrine activity" RELATED [GOC:rl];"paracrine activity" RELATED [GOC:rl]
molecular_function	GO:0005461	UDP-glucuronate transmembrane transporter activity
	name	UDP-glucuronate transmembrane transporter activity	WAS	UDP-glucuronic acid transmembrane transporter activity
	synonyms	"UDP-glucuronic acid transmembrane transporter activity" EXACT []	WAS	N/A
molecular_function	GO:0005476	carnitine:O-acyl-L-carnitine antiporter activity
	name	carnitine:O-acyl-L-carnitine antiporter activity	WAS	carnitine:acyl carnitine antiporter activity
molecular_function	GO:0008146	sulfotransferase activity
	definition	"Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate." [EC:2.8.2.-]	WAS	"Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate." [GOC:curators]
molecular_function	GO:0008233	peptidase activity
	definition	"Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid." [EC:3.4.-.-, GOC:jl]	WAS	"Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid." [GOC:jl, ISBN:0815332181]
molecular_function	GO:0008241	peptidyl-dipeptidase activity
	definition	"Catalysis of the release of C-terminal dipeptides from a polypeptide chain." [EC:3.4.15.-, GOC:mb]	WAS	"Catalysis of the release of C-terminal dipeptides from a polypeptide chain." [GOC:mb]
molecular_function	GO:0008395	steroid hydroxylase activity
	synonyms	"cytochrome P450 CYP2G1" NARROW [];"olfactory-specific steroid hydroxylase activity" NARROW [];"steroid monooxygenase activity" EXACT []	WAS	"cytochrome P450 CYP2G1" NARROW [];"olfactory-specific steroid hydroxylase activity" NARROW []
molecular_function	GO:0008412	4-hydroxybenzoate polyprenyltransferase activity
	synonyms	"4-HB polyprenyltransferase activity" EXACT [];"4-hydroxybenzoate nonaprenyltransferase activity" NARROW [EC:2.5.1.39];"para-hydroxybenzoate transferase activity" EXACT [];"para-hydroxybenzoate-polyprenyl diphosphate transferase activity" EXACT [];"para-hydroxybenzoate:polyprenyltransferase activity" EXACT [];"PHB polyprenyl diphosphate transferase activity" EXACT []	WAS	"4-HB polyprenyltransferase activity" EXACT [];"para-hydroxybenzoate transferase activity" EXACT [];"para-hydroxybenzoate-polyprenyl diphosphate transferase activity" EXACT [];"para-hydroxybenzoate:polyprenyltransferase activity" EXACT [];"PHB polyprenyl diphosphate transferase activity" EXACT []
molecular_function	GO:0008425	2-methoxy-6-polyprenyl-1,4-benzoquinol methyltransferase activity
	name	2-methoxy-6-polyprenyl-1,4-benzoquinol methyltransferase activity	WAS	2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity
	synonyms	"2-polyprenyl-6-methoxy-1,4-benzoquinone methylase activity" EXACT [];"2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity" EXACT [];"coenzyme Q biosynthesis methyltransferase activity" EXACT [];"coenzyme Q biosynthetic process methyltransferase activity" EXACT [];"ubiquinone biosynthesis methyltransferase activity" BROAD [];"ubiquinone biosynthetic process methyltransferase activity" BROAD []	WAS	"2-polyprenyl-6-methoxy-1,4-benzoquinone methylase activity" EXACT [];"coenzyme Q biosynthesis methyltransferase activity" EXACT [];"coenzyme Q biosynthetic process methyltransferase activity" EXACT [];"ubiquinone biosynthesis methyltransferase activity" BROAD [];"ubiquinone biosynthetic process methyltransferase activity" BROAD []
molecular_function	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase activity
	name	[heparan sulfate]-glucosamine 3-sulfotransferase activity	WAS	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity
	synonyms	"3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase" BROAD [];"3'-phosphoadenylyl-sulfate:heparin-glucosamine 3-O-sulfotransferase activity" RELATED [];"3-OST activity" RELATED [];"[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity" NARROW [];"[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity" NARROW [];"[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity" NARROW [];"glucosaminyl 3-O-sulfotransferase activity" RELATED [];"heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity" RELATED [];"heparin-glucosamine 3-O-sulfotransferase activity" RELATED [];"heparin-glucosamine 3-O-sulphotransferase activity" RELATED []	WAS	"3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase" BROAD [EC:2.8.2.23];"3'-phosphoadenylyl-sulfate:heparin-glucosamine 3-O-sulfotransferase activity" RELATED [EC:2.8.2.23];"3-OST-1 activity" RELATED [EC:2.8.2.23];"glucosaminyl 3-O-sulfotransferase activity" RELATED [EC:2.8.2.23];"heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity" RELATED [EC:2.8.2.23];"heparin-glucosamine 3-O-sulfotransferase activity" RELATED [];"heparin-glucosamine 3-O-sulphotransferase activity" RELATED [];"isoform/isozyme 1 (3-OST-1, HS3ST1)" RELATED [EC:2.8.2.23]
molecular_function	GO:0008709	cholate 7-alpha-dehydrogenase (NAD+) activity
	name	cholate 7-alpha-dehydrogenase (NAD+) activity	WAS	cholate 7-alpha-dehydrogenase activity
molecular_function	GO:0008834	ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] activity
	name	ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] activity	WAS	di-trans,poly-cis-undecaprenyl-diphosphate synthase activity
	synonyms	"bactoprenyl-diphosphate synthase activity" RELATED [EC:2.5.1.31];"di-trans,poly-cis-decaprenyl-diphosphate:isopentenyl-diphosphate undecaprenylcistransferase activity" RELATED [EC:2.5.1.31];"di-trans,poly-cis-decaprenylcistransferase activity" EXACT [];"di-trans,poly-cis-undecaprenyl-diphosphate synthase activity" EXACT [EC:2.5.1.31];"undecaprenyl diphosphate synthase activity" EXACT [];"undecaprenyl diphosphate synthetase activity" RELATED [EC:2.5.1.31];"undecaprenyl pyrophosphate synthase activity" RELATED [EC:2.5.1.31];"undecaprenyl pyrophosphate synthetase activity" RELATED [EC:2.5.1.31];"undecaprenyl-diphosphate synthase activity" RELATED [EC:2.5.1.31];"UPP synthetase activity" RELATED [EC:2.5.1.31]	WAS	"bactoprenyl-diphosphate synthase activity" RELATED [EC:2.5.1.31];"di-trans,poly-cis-decaprenyl-diphosphate:isopentenyl-diphosphate undecaprenylcistransferase activity" RELATED [EC:2.5.1.31];"di-trans,poly-cis-decaprenylcistransferase activity" EXACT [];"undecaprenyl diphosphate synthase activity" EXACT [];"undecaprenyl diphosphate synthetase activity" RELATED [EC:2.5.1.31];"undecaprenyl pyrophosphate synthase activity" RELATED [EC:2.5.1.31];"undecaprenyl pyrophosphate synthetase activity" RELATED [EC:2.5.1.31];"undecaprenyl-diphosphate synthase activity" RELATED [EC:2.5.1.31];"UPP synthetase activity" RELATED [EC:2.5.1.31]
molecular_function	GO:0008970	phospholipase A1 activity
	synonyms	"phosphatidylcholine 1-acylhydrolase activity" EXACT [];"phosphatidylserine 1-acylhydrolase activity" NARROW []	WAS	"phosphatidylcholine 1-acylhydrolase activity" EXACT []
molecular_function	GO:0010176	homogentisate phytyltransferase activity
	synonyms	"HPT activity" EXACT [EC:2.5.1.115]	WAS	N/A
molecular_function	GO:0010291	beta-carotene 3-hydroxylase activity
	name	beta-carotene 3-hydroxylase activity	WAS	carotene beta-ring hydroxylase activity
	synonyms	"beta-carotene hydroxylase activity" NARROW [];"carotene beta-ring hydroxylase activity" RELATED []	WAS	"beta-carotene hydroxylase activity" NARROW []
molecular_function	GO:0010356	homogentisate geranylgeranyltransferase activity
	synonyms	"HGGT activity" EXACT [EC:2.5.1.116];"homogentisate geranylgeranyl transferase activity" EXACT [PMID:21223386]	WAS	"homogentisate geranylgeranyl transferase activity" EXACT [PMID:21223386]
molecular_function	GO:0010357	homogentisate solanesyltransferase activity
	synonyms	"homogentisate solanyltransferase activity" EXACT [];"HST activity" EXACT [EC:2.5.1.117]	WAS	"homogentisate solanyltransferase activity" EXACT []
molecular_function	GO:0010420	polyprenyldihydroxybenzoate methyltransferase activity
	name	polyprenyldihydroxybenzoate methyltransferase activity	WAS	3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity
	synonyms	"3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity" EXACT [EC:2.1.1.114]	WAS	"polyprenyldihydroxybenzoate methyltransferase activity" RELATED []
molecular_function	GO:0015016	heparan sulfate N-sulfotransferase activity
	name	heparan sulfate N-sulfotransferase activity	WAS	[heparan sulfate]-glucosamine N-sulfotransferase activity
	synonyms	"3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine N-sulfotransferase activity" RELATED [EC:2.8.2.8];"3'-phosphoadenylyl-sulfate:heparitin N-sulfotransferase activity" RELATED [EC:2.8.2.8];"3'-phosphoadenylyl-sulfate:N-desulfoheparin N-sulfotransferase activity" RELATED [EC:2.8.2.8];"3'-phosphoadenylylsulfate:N-desulfoheparin sulfotransferase activity" RELATED [EC:2.8.2.8];"[heparan sulfate]-glucosamine N-sulfotransferase activity" EXACT [];"[heparan sulphate]-glucosamine N-sulphotransferase activity" EXACT [];"desulfoheparin sulfotransferase activity" EXACT [];"glucosaminyl N-deacetylase/N-sulfotransferase activity" RELATED [EC:2.8.2.8];"heparan sulfate 2-N-sulfotransferase activity" RELATED [EC:2.8.2.8];"heparan sulfate N-deacetylase/N-sulfotransferase activity" RELATED [EC:2.8.2.8];"heparin N-deacetylase/N-sulfotransferase activity" RELATED [];"heparin N-deacetylase/N-sulphotransferase activity" RELATED [];"heparin N-sulfotransferase activity" RELATED [EC:2.8.2.8];"heparin-glucosamine N-sulfotransferase activity" EXACT [];"heparitin N-sulfotransferase activity" EXACT [];"heparitin N-sulphotransferase activity" EXACT [];"heparitin sulfotransferase activity" EXACT [];"N-desulfoheparin sulfotransferase activity" RELATED [EC:2.8.2.8];"N-heparan sulfate sulfotransferase activity" RELATED [EC:2.8.2.8];"N-HSST activity" RELATED [EC:2.8.2.8];"PAPS:DSH sulfotransferase activity" RELATED [EC:2.8.2.8];"PAPS:N-desulfoheparin sulfotransferase activity" RELATED [EC:2.8.2.8]	WAS	"3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine N-sulfotransferase activity" RELATED [EC:2.8.2.8];"3'-phosphoadenylyl-sulfate:heparitin N-sulfotransferase activity" RELATED [EC:2.8.2.8];"3'-phosphoadenylyl-sulfate:N-desulfoheparin N-sulfotransferase activity" RELATED [EC:2.8.2.8];"3'-phosphoadenylylsulfate:N-desulfoheparin sulfotransferase activity" RELATED [EC:2.8.2.8];"[heparan sulphate]-glucosamine N-sulphotransferase activity" EXACT [];"desulfoheparin sulfotransferase activity" EXACT [];"glucosaminyl N-deacetylase/N-sulfotransferase activity" RELATED [EC:2.8.2.8];"heparan sulfate 2-N-sulfotransferase activity" RELATED [EC:2.8.2.8];"heparan sulfate N-deacetylase/N-sulfotransferase activity" RELATED [EC:2.8.2.8];"heparan sulfate N-sulfotransferase activity" RELATED [EC:2.8.2.8];"heparin N-deacetylase/N-sulfotransferase activity" RELATED [];"heparin N-deacetylase/N-sulphotransferase activity" RELATED [];"heparin N-sulfotransferase activity" RELATED [EC:2.8.2.8];"heparin-glucosamine N-sulfotransferase activity" EXACT [];"heparitin N-sulfotransferase activity" EXACT [];"heparitin N-sulphotransferase activity" EXACT [];"heparitin sulfotransferase activity" EXACT [];"N-desulfoheparin sulfotransferase activity" RELATED [EC:2.8.2.8];"N-heparan sulfate sulfotransferase activity" RELATED [EC:2.8.2.8];"N-HSST activity" RELATED [EC:2.8.2.8];"PAPS:DSH sulfotransferase activity" RELATED [EC:2.8.2.8];"PAPS:N-desulfoheparin sulfotransferase activity" RELATED [EC:2.8.2.8]
molecular_function	GO:0015227	O-acyl-L-carnitine transmembrane transporter activity
	name	O-acyl-L-carnitine transmembrane transporter activity	WAS	acyl carnitine transmembrane transporter activity
	definition	"Enables the transfer of O-acyl-L-carnitine from one side of a membrane to the other. O-acyl-L-carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane." [GOC:ai]	WAS	"Enables the transfer of acyl carnitine from one side of a membrane to the other. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane." [GOC:ai]
molecular_function	GO:0015280	ligand-gated sodium channel activity
	synonyms	"acid-sensing ion channel activity" NARROW [GOC:fj];"epithelial sodium channel" NARROW [GOC:fj]	WAS	"acid-sensing ion channel activity" NARROW [GOC:fj];"amiloride-sensitive sodium channel activity" NARROW [GOC:fj];"ASIC activity" NARROW [GOC:fj];"epithelial sodium channel" NARROW [GOC:fj]
molecular_function	GO:0016172	antifreeze activity
	is_obsolete	False	WAS	True
	name	antifreeze activity	WAS	obsolete antifreeze activity
	definition	"Inhibits the growth and recrystallization of ice crystals, thereby lowering the freezing point of water and preventing cellular damage at subzero temperatures. This activity is observed in various cold-adapted organisms, including certain fish, insects, and plants, and contributes to survival in extreme cold environments by stabilizing supercooled liquid states." [GOC:cjm, PMID:33317024]	WAS	"OBSOLETE. Inhibits the formation of ice crystals in organismal fluid (e.g. blood) at below freezing exogenous temperatures." [GOC:jl]
	comment	Note that this term was reinstated from obsolete.	WAS	This term was made obsolete because it refers to a biological process.
	synonyms	N/A	WAS	"antifreeze activity" EXACT []
molecular_function	GO:0016285	alanyl aminopeptidase activity
	is_obsolete	False	WAS	True
	name	alanyl aminopeptidase activity	WAS	obsolete cytosol alanyl aminopeptidase activity
	definition	"Catalysis of the release of an N-terminal amino acid, preferentially alanine, from a wide range of peptides, amides and arylamides." [EC:3.4.11.14]	WAS	"OBSOLETE. Catalysis of the release of an N-terminal amino acid, preferentially alanine, from a wide range of peptides, amides and arylamides." [EC:3.4.11.14]
	comment	N/A	WAS	This term was made obsolete because it represents a gene product and refers to cellular component information.
	synonyms	"aminopolypeptidase activity" BROAD [EC:3.4.11.14];"arylamidase activity" NARROW [EC:3.4.11.14];"cytosol alanyl aminopeptidase activity" EXACT [];"cytosol aminopeptidase III activity" NARROW [EC:3.4.11.14];"human liver aminopeptidase" NARROW [EC:3.4.11.14];"liver aminopeptidase activity" NARROW [EC:3.4.11.14];"membrane alanine aminopeptidase" NARROW [];"membrane alanyl aminopeptidase" NARROW [];"puromycin-sensitive aminopeptidase activity" NARROW [EC:3.4.11.14];"soluble alanyl aminopeptidase activity" RELATED [EC:3.4.11.14];"thiol-activated aminopeptidase activity" RELATED [EC:3.4.11.14]	WAS	"aminopolypeptidase activity" RELATED [EC:3.4.11.14];"arylamidase activity" NARROW [EC:3.4.11.14];"cytosol alanyl aminopeptidase activity" EXACT [];"cytosol aminopeptidase III activity" NARROW [EC:3.4.11.14];"human liver aminopeptidase" NARROW [EC:3.4.11.14];"liver aminopeptidase activity" NARROW [EC:3.4.11.14];"puromycin-sensitive aminopeptidase activity" NARROW [EC:3.4.11.14];"soluble alanyl aminopeptidase activity" RELATED [EC:3.4.11.14];"thiol-activated aminopeptidase activity" RELATED [EC:3.4.11.14]
molecular_function	GO:0016664	oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor
	definition	"Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces an iron-sulfur protein." [EC:1.7.7.-]	WAS	"Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces an iron-sulfur protein." [GOC:jl]
molecular_function	GO:0016805	dipeptidase activity
	definition	"Catalysis of the hydrolysis of a dipeptide." [EC:3.4.13.-, https://www.ebi.ac.uk/merops/about/glossary.shtml#DIPEPTIDASE, PMID:19879002]	WAS	"Catalysis of the hydrolysis of a dipeptide." [https://www.ebi.ac.uk/merops/about/glossary.shtml#DIPEPTIDASE, PMID:19879002]
molecular_function	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives
	definition	"Catalysis of a reaction that alters the configuration of one or more chiral centers in a carbohydrate molecule." [EC:5.1.3.-, GOC:mah]	WAS	"Catalysis of a reaction that alters the configuration of one or more chiral centers in a carbohydrate molecule." [GOC:mah]
molecular_function	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses
	definition	"Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is an aldose or a ketose, are the same molecule, and no oxidized product appears." [EC:5.3.1.-, GOC:jl]	WAS	"Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is an aldose or a ketose, are the same molecule, and no oxidized product appears." [GOC:jl]
molecular_function	GO:0016862	intramolecular oxidoreductase activity, interconverting keto- and enol-groups
	definition	"Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is a keto- or an enol-group, are the same molecule, and no oxidized product appears." [EC:5.3.2.-, GOC:jl]	WAS	"Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is a keto- or an enol-group, are the same molecule, and no oxidized product appears." [GOC:jl]
molecular_function	GO:0017095	heparan sulfate 6-sulfotransferase activity
	name	heparan sulfate 6-sulfotransferase activity	WAS	heparan sulfate 6-O-sulfotransferase activity
	synonyms	"heparan sulfate 6-O-sulfotransferase activity" EXACT [];"heparan sulphate 6-O-sulphotransferase activity" EXACT [];"heparin 6-O-sulfotransferase activity" RELATED []	WAS	"heparan sulphate 6-O-sulphotransferase activity" EXACT [];"heparin 6-O-sulfotransferase activity" RELATED []
molecular_function	GO:0019833	ice nucleation activity
	is_obsolete	False	WAS	True
	name	ice nucleation activity	WAS	obsolete ice nucleation activity
	definition	"Catalysis of the formation of ice crystals in extracellular fluid at relatively high temperatures (up to -2 degrees Celsius) to protect the organism from damage by intracellular ice formation. This process is commonly found in certain bacteria, such as Pseudomonas syringae, and plays roles in environmental adaptation and plant pathogenesis." [GOC:cjm, PMID:35551271, UniProt:KW-0387]	WAS	"OBSOLETE. Catalysis of the formation of ice crystals in extracellular fluid at relatively high temperatures (up to -2 degrees C) to protect the organism from damage by intracellular ice formation. Ice nucleation proteins function by binding an ice crystal and then encouraging it to form larger crystals. Ice nucleation is a chemical process but these proteins can positively regulate it. There are two different uses of ice nucleation proteins
	comment	Note that this term was reinstated from obsolete.	WAS	This term was made obsolete because it represents a biological process.
	synonyms	N/A	WAS	"ice nucleation activity" EXACT []
molecular_function	GO:0030284	nuclear estrogen receptor activity
	definition	"A nuclear receptor activity regulated by estrogen binding and modulating the transcription of specific gene sets transcribed by RNA polymerase II." [GOC:signaling, PMID:17615392]	WAS	"Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function." [GOC:signaling, PMID:17615392]
molecular_function	GO:0030378	serine racemase activity
	definition	"Catalysis of the reaction	WAS	"Catalysis of the synthesis of free D-serine from L-serine." [GOC:kd]
molecular_function	GO:0030674	protein-macromolecule adaptor activity
	definition	"An adaptor activity that brings together two or more macromolecules in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid." [GOC:bf, GOC:mah, GOC:vw]	WAS	"The binding activity of a protein that brings together two or more macromolecules in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid." [GOC:bf, GOC:mah, GOC:vw]
molecular_function	GO:0031963	nuclear cortisol receptor activity
	definition	"A nuclear receptor activity regulated by cortisol binding and modulating the transcription of specific gene sets transcribed by RNA polymerase II." [GOC:mah, PMID:12511169]	WAS	"Combining with cortisol and transmitting the signal within the cell to trigger a change in cell activity or function." [GOC:mah, PMID:12511169]
molecular_function	GO:0033703	3-beta-hydroxy-5-beta-steroid dehydrogenase (NADP+) activity
	name	3-beta-hydroxy-5-beta-steroid dehydrogenase (NADP+) activity	WAS	3beta-hydroxy-5beta-steroid dehydrogenase activity
molecular_function	GO:0033704	3-beta-hydroxy-5-alpha-steroid dehydrogenase (NADP+) activity
	name	3-beta-hydroxy-5-alpha-steroid dehydrogenase (NADP+) activity	WAS	3beta-hydroxy-5alpha-steroid dehydrogenase activity
molecular_function	GO:0033782	24S-hydroxycholesterol 7-alpha-hydroxylase activity
	name	24S-hydroxycholesterol 7-alpha-hydroxylase activity	WAS	24-hydroxycholesterol 7alpha-hydroxylase activity
	synonyms	"24-cholest-5-ene-3beta,24-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity" RELATED [];"24-hydroxycholesterol 7alpha-hydroxylase activity" BROAD [];"24-hydroxycholesterol 7alpha-monooxygenase activity" RELATED [EC:1.14.14.26]	WAS	"24-cholest-5-ene-3beta,24-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity" RELATED [];"24-hydroxycholesterol 7alpha-monooxygenase activity" RELATED [EC:1.14.14.26]
molecular_function	GO:0033783	25-hydroxycholesterol 7-alpha-hydroxylase activity
	name	25-hydroxycholesterol 7-alpha-hydroxylase activity	WAS	25-hydroxycholesterol 7alpha-hydroxylase activity
molecular_function	GO:0033842	N-acetyl-beta-glucosaminyl-derivative 4-beta-N-acetylgalactosaminyltransferase activity
	name	N-acetyl-beta-glucosaminyl-derivative 4-beta-N-acetylgalactosaminyltransferase activity	WAS	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity
	synonyms	"beta1,4-N-acetylgalactosaminyltransferase activity" RELATED [EC:2.4.1.244];"beta1,4-N-acetylgalactosaminyltransferase III activity" RELATED [EC:2.4.1.244];"beta1,4-N-acetylgalactosaminyltransferase IV activity" RELATED [EC:2.4.1.244];"beta4GalNAc-T3" RELATED [EC:2.4.1.244];"beta4GalNAc-T4" RELATED [EC:2.4.1.244];"N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity" EXACT [EC:2.4.1.244];"UDP-N-acetyl-D-galactosamine:N-acetyl-D-glucosaminyl-group beta-1,4-N-acetylgalactosaminyltransferase activity" RELATED [EC:2.4.1.244]	WAS	"beta1,4-N-acetylgalactosaminyltransferase activity" RELATED [EC:2.4.1.244];"beta1,4-N-acetylgalactosaminyltransferase III activity" RELATED [EC:2.4.1.244];"beta1,4-N-acetylgalactosaminyltransferase IV activity" RELATED [EC:2.4.1.244];"beta4GalNAc-T3" RELATED [EC:2.4.1.244];"beta4GalNAc-T4" RELATED [EC:2.4.1.244];"UDP-N-acetyl-D-galactosamine:N-acetyl-D-glucosaminyl-group beta-1,4-N-acetylgalactosaminyltransferase activity" RELATED [EC:2.4.1.244]
molecular_function	GO:0034482	chondroitin 2-sulfotransferase activity
	name	chondroitin 2-sulfotransferase activity	WAS	chondroitin 2-O-sulfotransferase activity
	synonyms	"chondroitin 2-O-sulfotransferase activity" EXACT [];"chondroitin 2-O-sulphotransferase activity" EXACT []	WAS	"chondroitin 2-O-sulphotransferase activity" EXACT [];"chondroitin 2-sulfotransferase activity" EXACT []
molecular_function	GO:0035302	ecdysteroid 25-hydroxylase activity
	definition	"Catalysis of the hydroxylation of an ecdysteroid at carbon position 25." [PMID:15350618]	WAS	"Catalysis of the hydroxylation of an ecdysteroid at carbon position 25. Ecdysteroids are a group of polyhydroxylated ketosteroids which initiate post-embryonic development, particularly metamorphosis, in insects and other arthropods." [ISBN:0198506732, PMID:15350618]
molecular_function	GO:0036185	13-lipoxin reductase activity
	definition	"Catalysis of the reaction	WAS	"Definition
molecular_function	GO:0036423	hexaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) activity
	synonyms	"hexaprenyl diphosphate synthase activity" BROAD [EC:2.5.1.83];"hexaprenyl pyrophosphate synthetase activity" BROAD [EC:2.5.1.83];"HexPS activity" EXACT [EC:2.5.1.83]	WAS	"hexaprenyl diphosphate synthase activity" BROAD [EC:2.5.1.83];"hexaprenyl pyrophosphate synthetase activity" BROAD [EC:2.5.1.83]
molecular_function	GO:0038186	bile acid nuclear receptor activity
	definition	"A nuclear receptor activity regulated by a bile acid binding and modulating the transcription of specific gene sets transcribed by RNA polymerase II." [PMID:32480317, PMID:35415765, PMID:36409000]	WAS	"A DNA-binding transcription factor activity regulated by binding to a bile acid that modulates the transcription of specific gene sets transcribed by RNA polymerase II." [PMID:32480317, PMID:35415765, PMID:36409000]
molecular_function	GO:0042409	caffeoyl-CoA O-methyltransferase activity
	synonyms	"caffeoyl CoA:S-adenosyl-L-methionine O-methyltransferase activity" EXACT [];"caffeoyl coenzyme A methyltransferase activity" EXACT [];"caffeoyl-CoA 3-O-methyltransferase activity" EXACT [];"S-adenosyl-L-methionine:caffeoyl-CoA 3-O-methyltransferase activity" RELATED [EC:2.1.1.104];"trans-caffeoyl-CoA 3-O-methyltransferase activity" RELATED [EC:2.1.1.104]	WAS	"caffeoyl coenzyme A methyltransferase activity" EXACT [];"caffeoyl-CoA 3-O-methyltransferase activity" EXACT [];"S-adenosyl-L-methionine:caffeoyl-CoA 3-O-methyltransferase activity" RELATED [EC:2.1.1.104];"trans-caffeoyl-CoA 3-O-methyltransferase activity" RELATED [EC:2.1.1.104]
molecular_function	GO:0042767	ecdysteroid 22-hydroxylase activity
	synonyms	"3-dehydro-2,22-dideoxyecdysone 22-hydroxylase activity" NARROW [EC:1.14.15.44]	WAS	N/A
molecular_function	GO:0042768	ecdysteroid 2-hydroxylase activity
	definition	"Catalysis of the hydroxylation of an ecdysteroid at carbon position 2." [PMID:12177427]	WAS	"Catalysis of the reaction
molecular_function	GO:0044687	geranylfarnesyl diphosphate synthase activity
	synonyms	"FGPP synthase activity" EXACT [EC:2.5.1.81]	WAS	N/A
molecular_function	GO:0045547	ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity
	name	ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity	WAS	dehydrodolichyl diphosphate synthase activity
	definition	"Catalysis of the reaction	WAS	"Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate." [PMID:9858571]
	synonyms	"dehydrodolichyl diphosphate synthase activity" EXACT [EC:2.5.1.87]	WAS	N/A
molecular_function	GO:0046562	beta-D-glucose oxidase activity
	name	beta-D-glucose oxidase activity	WAS	glucose oxidase activity
	synonyms	"beta-D-glucose:oxygen 1-oxido-reductase activity" RELATED [EC:1.1.3.4];"beta-D-glucose:oxygen 1-oxidoreductase activity" RELATED [EC:1.1.3.4];"beta-D-glucose:quinone oxidoreductase activity" RELATED [EC:1.1.3.4];"corylophyline" RELATED [EC:1.1.3.4];"D-glucose oxidase activity" RELATED [EC:1.1.3.4];"D-glucose-1-oxidase activity" RELATED [EC:1.1.3.4];"deoxin-1" RELATED [EC:1.1.3.4];"glucose aerodehydrogenase activity" RELATED [EC:1.1.3.4];"glucose oxidase activity" EXACT [];"glucose oxyhydrase activity" RELATED [EC:1.1.3.4];"GOD activity" RELATED [EC:1.1.3.4];"microcid" RELATED [EC:1.1.3.4];"penatin" RELATED [EC:1.1.3.4]	WAS	"beta-D-glucose oxidase activity" EXACT [];"beta-D-glucose:oxygen 1-oxido-reductase activity" RELATED [EC:1.1.3.4];"beta-D-glucose:oxygen 1-oxidoreductase activity" RELATED [EC:1.1.3.4];"beta-D-glucose:quinone oxidoreductase activity" RELATED [EC:1.1.3.4];"corylophyline" RELATED [EC:1.1.3.4];"D-glucose oxidase activity" RELATED [EC:1.1.3.4];"D-glucose-1-oxidase activity" RELATED [EC:1.1.3.4];"deoxin-1" RELATED [EC:1.1.3.4];"glucose aerodehydrogenase activity" RELATED [EC:1.1.3.4];"glucose oxyhydrase activity" RELATED [EC:1.1.3.4];"GOD activity" RELATED [EC:1.1.3.4];"microcid" RELATED [EC:1.1.3.4];"penatin" RELATED [EC:1.1.3.4]
molecular_function	GO:0046905	15-cis-phytoene synthase activity
	comment	N/A	WAS	Note that this should not be confused with 'geranylgeranyl-diphosphate geranylgeranyltransferase activity ; GO:0016767', EC:2.5.1.32. This activity is the second part of the formation of phytoene from geranylgeranyl-diphosphate, the first stage of which is catalyzed by EC:2.5.1.32.
	synonyms	"geranylgeranyl-diphosphate geranylgeranyltransferase activity" EXACT [EC:2.5.1.32];"geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase (15-cis-phytoene-forming) activity" EXACT [EC:2.5.1.32];"phytoene synthase activity" EXACT [EC:2.5.1.32];"prephytoene-diphosphate synthase activity" EXACT [EC:2.5.1.32];"PSase activity" EXACT [EC:2.5.1.32]	WAS	"phytoene synthase activity" BROAD []
molecular_function	GO:0047005	16-alpha-hydroxysteroid dehydrogenase [NAD(P)+] activity
	name	16-alpha-hydroxysteroid dehydrogenase [NAD(P)+] activity	WAS	16-alpha-hydroxysteroid dehydrogenase (NADP+) activity
molecular_function	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase [NAD(P)+] activity
	name	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase [NAD(P)+] activity	WAS	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
	synonyms	"17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity" EXACT [];"20alpha-HSD" RELATED [EC:1.1.1.149];"20alpha-HSDH" RELATED [EC:1.1.1.149];"20alpha-hydroxy steroid dehydrogenase activity" BROAD [EC:1.1.1.149];"20alpha-hydroxysteroid dehydrogenase" BROAD [EC:1.1.1.149];"20alpha-hydroxysteroid:NAD(P)+ 20-oxidoreductase activity" BROAD [EC:1.1.1.149]	WAS	"20alpha-HSD" RELATED [EC:1.1.1.149];"20alpha-HSDH" RELATED [EC:1.1.1.149];"20alpha-hydroxy steroid dehydrogenase activity" BROAD [EC:1.1.1.149];"20alpha-hydroxysteroid dehydrogenase" BROAD [EC:1.1.1.149];"20alpha-hydroxysteroid:NAD(P)+ 20-oxidoreductase activity" BROAD [EC:1.1.1.149]
molecular_function	GO:0047013	cholate 12-alpha dehydrogenase (NADP+) activity
	name	cholate 12-alpha dehydrogenase (NADP+) activity	WAS	cholate 12-alpha dehydrogenase activity
molecular_function	GO:0047023	androsterone dehydrogenase [NAD(P)+] activity
	name	androsterone dehydrogenase [NAD(P)+] activity	WAS	androsterone dehydrogenase activity
molecular_function	GO:0047024	5-alpha-androstane-3-beta,17-beta-diol dehydrogenase (NADP+) activity
	name	5-alpha-androstane-3-beta,17-beta-diol dehydrogenase (NADP+) activity	WAS	5alpha-androstane-3beta,17beta-diol dehydrogenase activity
	synonyms	"3-beta(or 20-alpha)-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.210];"3-beta-HSD activity" RELATED [EC:1.1.1.210];"3beta(or 20alpha)-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.210];"3beta(or 20alpha)-hydroxysteroid:NADP+ oxidoreductase activity" BROAD [EC:1.1.1.210];"3beta,20alpha-hydroxysteroid oxidoreductase activity" BROAD [EC:1.1.1.210];"5alpha-androstane-3beta,17beta-diol dehydrogenase activity" EXACT [];"dehydrogenase, 3beta,20alpha-hydroxy steroid" BROAD [EC:1.1.1.210];"progesterone reductase activity" RELATED [EC:1.1.1.210]	WAS	"3-beta(or 20-alpha)-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.210];"3-beta-HSD activity" RELATED [EC:1.1.1.210];"3beta(or 20alpha)-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.210];"3beta(or 20alpha)-hydroxysteroid:NADP+ oxidoreductase activity" BROAD [EC:1.1.1.210];"3beta,20alpha-hydroxysteroid oxidoreductase activity" BROAD [EC:1.1.1.210];"dehydrogenase, 3beta,20alpha-hydroxy steroid" BROAD [EC:1.1.1.210];"progesterone reductase activity" RELATED [EC:1.1.1.210]
molecular_function	GO:0047044	androstan-3-alpha,17-beta-diol dehydrogenase (NAD+) activity
	name	androstan-3-alpha,17-beta-diol dehydrogenase (NAD+) activity	WAS	androstan-3-alpha,17-beta-diol dehydrogenase activity
molecular_function	GO:0047294	phosphoglycerol geranylgeranyltransferase activity
	synonyms	"(S)-3-O-geranylgeranylglyceryl phosphate synthase activity" EXACT [];"geranylgeranyl diphosphate:sn-glyceryl phosphate geranylgeranyltransferase activity" RELATED [EC:2.5.1.41];"geranylgeranyl-transferase activity" RELATED [EC:2.5.1.41];"GGGP synthase activity" EXACT [EC:2.5.1.41];"GGGPS activity" EXACT [EC:2.5.1.41];"glycerol phosphate geranylgeranyltransferase activity" RELATED [EC:2.5.1.41]	WAS	"(S)-3-O-geranylgeranylglyceryl phosphate synthase activity" EXACT [];"geranylgeranyl diphosphate:sn-glyceryl phosphate geranylgeranyltransferase activity" RELATED [EC:2.5.1.41];"geranylgeranyl-transferase activity" RELATED [EC:2.5.1.41];"glycerol phosphate geranylgeranyltransferase activity" RELATED [EC:2.5.1.41]
molecular_function	GO:0047295	geranylgeranylglycerol-phosphate geranylgeranyltransferase activity
	synonyms	"(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity" EXACT [];"DGGGP synthase activity" EXACT [EC:2.5.1.42];"geranylgeranyl diphosphate:sn-3-O-(geranylgeranyl)glycerol 1-phosphate geranylgeranyltransferase activity" RELATED [EC:2.5.1.42];"geranylgeranyloxyglycerol phosphate geranylgeranyltransferase activity" RELATED [EC:2.5.1.42];"geranylgeranyltransferase II" RELATED [EC:2.5.1.42]	WAS	"(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity" EXACT [];"geranylgeranyl diphosphate:sn-3-O-(geranylgeranyl)glycerol 1-phosphate geranylgeranyltransferase activity" RELATED [EC:2.5.1.42];"geranylgeranyloxyglycerol phosphate geranylgeranyltransferase activity" RELATED [EC:2.5.1.42];"geranylgeranyltransferase II" RELATED [EC:2.5.1.42]
molecular_function	GO:0047521	12-beta-hydroxysteroid dehydrogenase (NADP+) activity
	name	12-beta-hydroxysteroid dehydrogenase (NADP+) activity	WAS	3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity
	synonyms	"12beta-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity" BROAD [EC:1.1.1.238];"12beta-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.238];"12beta-hydroxysteroid:NADP+ 12-oxidoreductase activity" BROAD [EC:1.1.1.238];"3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity" BROAD [EC:1.1.1.238]	WAS	"12-beta-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.238];"12beta-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity" BROAD [EC:1.1.1.238];"12beta-hydroxysteroid dehydrogenase activity" BROAD [EC:1.1.1.238];"12beta-hydroxysteroid:NADP+ 12-oxidoreductase activity" BROAD [EC:1.1.1.238]
molecular_function	GO:0047751	3-oxo-5-alpha-steroid 4-dehydrogenase (NADP+) activity
	name	3-oxo-5-alpha-steroid 4-dehydrogenase (NADP+) activity	WAS	3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) activity
molecular_function	GO:0047791	cucurbitacin Delta23 reductase [NAD(P)H] activity
	name	cucurbitacin Delta23 reductase [NAD(P)H] activity	WAS	cucurbitacin delta23-reductase activity
molecular_function	GO:0050497	alkylthioltransferase activity
	definition	"Catalysis of the transfer of an alkylthio group from one compound (donor) to another (acceptor)." [EC:2.8.4.-, GOC:ai]	WAS	"Catalysis of the transfer of an alkylthio group from one compound (donor) to another (acceptor)." [GOC:ai]
molecular_function	GO:0050613	Delta14-sterol reductase activity
	name	Delta14-sterol reductase activity	WAS	delta14-sterol reductase activity
molecular_function	GO:0050614	Delta24-sterol reductase activity
	name	Delta24-sterol reductase activity	WAS	delta24-sterol reductase activity
molecular_function	GO:0050825	ice binding
	synonyms	"ice crystal binding" EXACT [];"ice nucleation inhibitor activity" RELATED []	WAS	"antifreeze activity" RELATED [];"ice crystal binding" EXACT [];"ice nucleation activity" RELATED [];"ice nucleation inhibitor activity" RELATED []
molecular_function	GO:0051996	squalene synthase [NAD(P)H] activity
	synonyms	"farnesyl-diphosphate farnesyltransferase activity" NARROW [EC:2.5.1.21];"farnesyltransferase activity" BROAD [EC:2.5.1.21];"presqualene synthase activity" EXACT [EC:2.5.1.21];"presqualene-diphosphate synthase activity" EXACT [EC:2.5.1.21];"squalene synthase activity" EXACT [EC:2.5.1.21];"squalene synthetase activity" RELATED [EC:2.5.1.21]	WAS	"squalene synthetase activity" RELATED [EC:2.5.1.21]
molecular_function	GO:0052849	curcumin reductase (NADP+) activity
	name	curcumin reductase (NADP+) activity	WAS	NADPH-dependent curcumin reductase activity
	synonyms	"NADPH-dependent curcumin reductase activity" EXACT []	WAS	N/A
molecular_function	GO:0061542	3-demethylubiquinol 3-O-methyltransferase activity
	name	3-demethylubiquinol 3-O-methyltransferase activity	WAS	3-demethylubiquinol-n 3-O-methyltransferase activity
	synonyms	"2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase" NARROW [];"3-demethylubiquinol-n 3-O-methyltransferase activity" EXACT [];"5-demethylubiquinone-10 methyltransferase" NARROW [];"5-demethylubiquinone-9 methyltransferase" NARROW [];"OMHMB-methyltransferase" RELATED [];"S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase" RELATED []	WAS	"2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase" NARROW [];"5-demethylubiquinone-10 methyltransferase" NARROW [];"5-demethylubiquinone-9 methyltransferase" NARROW [];"OMHMB-methyltransferase" RELATED [];"S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase" RELATED []
molecular_function	GO:0061628	histone H3K27me3 reader activity
	name	histone H3K27me3 reader activity	WAS	H3K27me3 modified histone binding
	definition	"A histone reader that recognizes a histone H3 trimethylated at lysine 27." [GOC:dph, PMID:23948251]	WAS	"Binding to a histone H3 in which the lysine residue at position 27 has been modified by trimethylation." [GOC:dph, PMID:23948251]
	synonyms	"H3-K27me3 modified histone binding" NARROW [];"H3K27me3 modified histone binding" NARROW []	WAS	"H3-K27me3 modified histone binding" EXACT [GOC:dph]
molecular_function	GO:0061649	ubiquitin-modified histone reader activity
	definition	"A histone reader that recognizes a histone bearing a ubiquinated lysine residue." [PMID:24526689]	WAS	"A molecular adaptor that recognizes and binds a histone protein containing a ubiquitination modification and that brings the target protein into contact with another protein to allow those proteins to function in a coordinated way." [GOC:dph, PMID:24526689]
molecular_function	GO:0061776	ATP-dependent topological DNA co-entrapment activity
	name	ATP-dependent topological DNA co-entrapment activity	WAS	topological DNA co-entrapment activity
	synonyms	"ATP-dependent ring closure activity" EXACT [];"topological DNA entrapment activity" RELATED []	WAS	"topological DNA entrapment activity" RELATED []
molecular_function	GO:0062072	histone H3K9me3 reader activity
	name	histone H3K9me3 reader activity	WAS	H3K9me3 modified histone binding
	definition	"A histone reader that recognizes a histone H3 trimethylated at lysine 9." [PMID:30110338]	WAS	"Binding to a histone H3 in which the lysine residue at position 9 has been modified by trimethylation." [PMID:30110338]
	synonyms	"H3K9me3 modified histone binding" NARROW []	WAS	N/A
molecular_function	GO:0070497	6-carboxytetrahydropterin synthase activity
	name	6-carboxytetrahydropterin synthase activity	WAS	6-carboxy-5,6,7,8-tetrahydropterin synthase activity
	synonyms	"6-carboxy-5,6,7,8-tetrahydropterin synthase activity" EXACT []	WAS	N/A
molecular_function	GO:0090555	phosphatidylethanolamine flippase activity
	definition	"Catalysis of the movement of phosphatidylethanolamine from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP." [GOC:ab, PMID:16452632, PMID:20043909]	WAS	"Catalysis of the movement of phosphatidylethanolamine from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP." [GOC:ab, PMID:16452632, PMID:20043909, RHEA:36439]
molecular_function	GO:0097269	all-trans-decaprenyl-diphosphate synthase activity
	synonyms	"(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase activity" EXACT [];"2-trans,6-trans-farnesyl diphosphate activity" EXACT [];"decaprenyl pyrophosphate synthetase activity" BROAD [EC:2.5.1.91];"decaprenyl-diphosphate synthase activity" BROAD [EC:2.5.1.91];"polyprenylpyrophosphate synthetase activity" BROAD [EC:2.5.1.91];"terpenoidallyltransferase activity" BROAD [EC:2.5.1.91];"terpenyl pyrophosphate synthetase activity" BROAD [EC:2.5.1.91];"trans-prenyltransferase activity" BROAD [EC:2.5.1.91]	WAS	"(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase activity" EXACT [];"2-trans,6-trans-farnesyl diphosphate activity" EXACT []
molecular_function	GO:0098531	ligand-modulated transcription factor activity
	name	ligand-modulated transcription factor activity	WAS	ligand-activated transcription factor activity
	synonyms	"direct ligand regulated sequence-specific DNA binding transcription factor activity" EXACT [];"ligand-activated transcription factor activity" NARROW [];"transcription factor activity, direct ligand regulated sequence-specific DNA binding" EXACT []	WAS	"direct ligand regulated sequence-specific DNA binding transcription factor activity" EXACT [];"transcription factor activity, direct ligand regulated sequence-specific DNA binding" EXACT []
molecular_function	GO:0099618	UDP-glucuronate dehydrogenase activity
	name	UDP-glucuronate dehydrogenase activity	WAS	UDP-glucuronic acid dehydrogenase activity
	synonyms	"UDP-GlcUA decarboxylase activity" EXACT [];"UDP-glucuronic acid dehydrogenase activity" EXACT []	WAS	"UDP-GlcUA decarboxylase activity" EXACT []
molecular_function	GO:0102059	(2Z,6Z)-farnesyl diphosphate synthase activity
	name	(2Z,6Z)-farnesyl diphosphate synthase activity	WAS	2-cis,6-cis-farnesyl pyrophosphate synthase activity
	synonyms	"2-cis,6-cis-farnesyl pyrophosphate synthase activity" EXACT [];"cis,cis-farnesyl diphosphate synthase activity" EXACT [EC:2.5.1.92];"neryl-diphosphate:isopentenyl-diphosphate cistransferase activity" NARROW [];"Z,Z-farnesyl pyrophosphate synthase activity" EXACT [EC:2.5.1.92];"Z,Z-FPP synthase activity" EXACT [EC:2.5.1.92];"zFPS activity" EXACT [EC:2.5.1.92]	WAS	"neryl-diphosphate:isopentenyl-diphosphate cistransferase activity" NARROW []
molecular_function	GO:0102142	dermatan 2-sulfotransferase activity
	name	dermatan 2-sulfotransferase activity	WAS	[dermatan sulfate]-L-iduronyl 2-Osulfotransferase activity
	synonyms	"[dermatan sulfate]-L-iduronyl 2-Osulfotransferase activity" EXACT []	WAS	N/A
molecular_function	GO:0102175	3-beta-hydroxysteroid dehydrogenase (NAD+)/C4-decarboxylase activity
	name	3-beta-hydroxysteroid dehydrogenase (NAD+)/C4-decarboxylase activity	WAS	3-beta-hydroxysteroid dehydrogenase/C4-decarboxylase activity
molecular_function	GO:0102196	cortisol dehydrogenase (NAD+) activity
	name	cortisol dehydrogenase (NAD+) activity	WAS	cortisol dehydrogenase activity
molecular_function	GO:0102294	cholesterol dehydrogenase (NAD+) activity
	name	cholesterol dehydrogenase (NAD+) activity	WAS	cholesterol dehydrogenase activity
molecular_function	GO:0103031	L-Ala-D/L-Glu epimerase activity
	definition	"Catalysis of the reaction:L-alanyl-L-glutamate = L-alanyl-D-glutamate." [RHEA:28394]	WAS	"Catalysis of the reaction
molecular_function	GO:0103040	aldose sugar dehydrogenase activity
	comment	N/A	WAS	https://github.com/geneontology/go-ontology/issues/28942
molecular_function	GO:0106240	labd-13Z-ene-9,15,16-triol synthase activity
	definition	"Catalysis of the reaction	WAS	"Catalysis of the reaction:O2 + peregrinol + reduced [NADPH--hemoprotein reductase] = H+ + H2O + labd-13Z-ene-9,15,16-triol + oxidized [NADPH--hemoprotein reductase]." [GOC:eab, PMID:29315936, RHEA:62192]
molecular_function	GO:0106350	all-trans-octaprenyl-diphosphate synthase activity
	name	all-trans-octaprenyl-diphosphate synthase activity	WAS	octaprenyl pyrophosphate synthase activity
	synonyms	"octaprenyl pyrophosphate synthase activity" EXACT [EC:2.5.1.90];"terpenyl pyrophosphate synthetase activity" BROAD [EC:2.5.1.90];"trans-heptaprenyltranstransferase activity" EXACT [EC:2.5.1.90];"trans-prenyltransferase activity" BROAD [EC:2.5.1.90]	WAS	N/A
molecular_function	GO:0106364	4-hydroxy-3-all-trans-polyprenylbenzoate oxygenase activity
	name	4-hydroxy-3-all-trans-polyprenylbenzoate oxygenase activity	WAS	4-hydroxy-3-all-trans-hexaprenylbenzoate oxygenase activity
	definition	"Catalysis of the reaction	WAS	"4-hydroxy-3-all-trans-hexaprenylbenzoate + 2 H+ + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]." [PMID:21944752, RHEA:20361]
	synonyms	"4-hydroxy-3-all-trans-hexaprenylbenzoate oxygenase activity" NARROW []	WAS	N/A
molecular_function	GO:0140463	chromatin-protein adaptor activity
	definition	"An adaptor activity that brings together a protein and a region of the chromatin, such as a nucleosome, to establish or maintain the chromatin localization of the protein, or the complex to which it belongs." [PMID:32277274]	WAS	"The binding activity of a molecule that brings together a protein or a protein complex with a nucleosome, to establish or maintain the chromatin localization of the protein, or protein complex." [PMID:32277274]
molecular_function	GO:0140566	histone reader activity
	definition	"A chromatin adaptor activity that brings together a protein and a specific form of histone, either modified by a post-translational modification, or the unmodified form. Histone readers have roles in many processes, including in centromere function or in modulating the accessibility of cis-regulatory regions to the transcription machinery." [PMID:11498575, PMID:25688442, PMID:31082667, PMID:34726351]	WAS	"A chromatin adaptor that recognizes specific forms of histones, either modified by a post-translational modification, or the unmodified form. Histone readers have roles in many processes, including in centromere function or in modulating the accessibility of cis-regulatory regions to the transcription machinery." [PMID:11498575, PMID:25688442, PMID:31082667, PMID:32260176, PMID:34726351]
molecular_function	GO:0141096	ligand-modulated transcription repressor activity
	name	ligand-modulated transcription repressor activity	WAS	ligand-activated transcription repressor activity
	synonyms	"ligand-activated transcription repressor activity" NARROW []	WAS	N/A
molecular_function	GO:0141097	ligand-modulated transcription activator activity
	name	ligand-modulated transcription activator activity	WAS	ligand-activated transcription activator activity
	synonyms	"ligand-activated transcription activator activity" NARROW []	WAS	N/A
molecular_function	GO:0160197	dolichal reductase [NAD(P)+] activity
	name	dolichal reductase [NAD(P)+] activity	WAS	dolichal reductase activity
molecular_function	GO:0180044	borate channel activity
	comment	N/A	WAS	https://github.com/geneontology/go-ontology/issues/27487
molecular_function	GO:1990889	H4K20me3 modified histone binding
	definition	"A histone reader that recognizes a histone H4 trimethylated at lysine 20." [PMID:22150589]	WAS	"Binding to a histone H4 in which the lysine residue at position 20 has been modified by trimethylation." [PMID:22150589]
cellular_component	GO:0005599	collagen type X trimer
	definition	"A collagen homotrimer of alpha1(X) chains; type X collagen triple helices form hexagonal networks (sheets)." [PMID:21421911]	WAS	"A collagen homotrimer of alpha1(X) chains; type X collagen triple helices form hexagonal networks (sheets)." [ISBN:0721639976, PMID:21421911]
cellular_component	GO:0009390	dimethyl sulfoxide reductase complex
	definition	"An enzyme complex that catalyzes the formation of dimethyl sulfide from dimethyl sulfoxide." [PMID:21357619, PMID:3280546]	WAS	"An enzyme complex that catalyzes the formation of dimethyl sulfide from dimethyl sulfoxide." [UM-BBD_enzymeID:r0207]
cellular_component	GO:0060102	cuticular extracellular matrix
	name	cuticular extracellular matrix	WAS	collagen and cuticulin-based cuticle extracellular matrix
	definition	"A collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer. The cuticle serves essential functions in body morphology, locomotion, and environmental protection. An example of this component is found in Caenorhabditis elegans." [GOC:dph, GOC:kmv, ISSN:15518507, PMID:12619137]	WAS	"A collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer. The cuticle serves essential functions in body morphology, locomotion, and environmental protection. An example of this component is found in Caenorhabditis elegans." [GOC:dph, GOC:kmv, ISSN:15518507]
	synonyms	"collagen and cuticulin-based cuticle extracellular matrix" EXACT [];"collagen and cuticulin-based exoskeleton extracellular matrix" RELATED [];"cuticular ECM" EXACT []	WAS	"collagen and cuticulin-based exoskeleton extracellular matrix" RELATED []
cellular_component	GO:0062023	collagen-containing extracellular matrix
	synonyms	"collagen-containing ECM" EXACT []	WAS	N/A
cellular_component	GO:0062039	biofilm matrix
	definition	"A type of extracellular matrix that surrounds the cells within a microbial biofilm. The matrix is composed of extracellular polymeric substances including exopolysaccharides, proteins, nucleic acids, lipids, and other biomolecules." [PMID:22571672, PMID:27129222, PMID:28516088, PMID:32663461]	WAS	"A structure lying external to microbial cells. A biofilm is an aggregate of surface-associated cells, and the biofilm matrix is the envelope of polymeric substances that surrounds the cells." [GOC:BHF, PMID:22571672, PMID:27129222, PMID:28516088]
	subsets	gocheck_do_not_annotate	WAS	N/A
cellular_component	GO:0070505	pollen coat
	definition	"A layer of extracellular matrix deposited onto the surface of the pollen wall upon disintegration of the tapetal layer of the anther wall in the late stages of pollen development. The composition of this material is highly heterogeneous and includes waxes, lipid droplets, small aromatic molecules, and proteins. The pollen coat is proposed to have many functions, such as holding pollen in the anther until dispersal, facilitation of pollen dispersal, protection of pollen from water loss and UV radiation, and facilitation of adhesion of pollen to the stigma." [GOC:mah, GOC:rph, PMID:12930826, PMID:15012271, PMID:28955324]	WAS	"A layer of extracellular matrix deposited onto the surface of the pollen wall upon disintegration of the tapetal layer of the anther wall in the late stages of pollen development. The composition of this material is highly heterogeneous and includes waxes, lipid droplets, small aromatic molecules, and proteins. The pollen coat is proposed to have many functions, such as holding pollen in the anther until dispersal, facilitation of pollen dispersal, protection of pollen from water loss and UV radiation, and facilitation of adhesion of pollen to the stigma." [GOC:mah, GOC:rph, PMID:12930826, PMID:15012271]
cellular_component	GO:0098026	virus tail, tube
	definition	"The internal tube of the tail of some viruses. The virus tail tube is the channel for DNA ejection into the host cytoplasm." [PMID:33188213, VZ:3960]	WAS	"The internal tube of the contractile tails of some viruses. The virus tail tube is the channel for DNA ejection into the host cytoplasm." [GOC:bm, VZ:3960]
	comment	Applies in particular the Myoviridae bacteriophages. Many bacteriophages with dsDNA genomes, or Caudovirales, have a tail. The viral tail can be short (Podoviridae), long and non-contractile (Siphoviridae) or long and contractile (Myoviridae). The tail is the channel through which the phage genome is injected into the host bacterial cell.	WAS	Applies in particular the Myoviridae bacteriophages.
cellular_component	GO:0098646	interstitial hexagonal collagen network
	name	interstitial hexagonal collagen network	WAS	collagen sheet
	definition	"A hexagonal shaped collagen network formed by collagen type X trimer, mostly found in the cartilage hyaline matrix, which located in the interstitial area." [PMID:21421911, PMID:34948124]	WAS	"A protein complex that consists of collagen triple helices associated to form a sheet-like network." [GOC:dos, PMID:21421911]
	synonyms	"collagen hexagonal network" EXACT [PMID:21421911];"collagen sheet" EXACT []	WAS	"collagen hexagonal network" EXACT [PMID:21421911]
cellular_component	GO:0099535	synapse-associated extracellular matrix
	synonyms	"extra-synaptic extracellular matrix" EXACT [];"synapse-associated ECM" EXACT []	WAS	"extra-synaptic extracellular matrix" EXACT []
cellular_component	GO:0180022	RQC-trigger complex
	definition	"A ribosome disassembly complex which dissociates stalled ribsome subunits as part of the ribosome quality control pathway. RQT complex is composed of a RNA helicase-family protein yeast Rqt2 (human ASCC3), a ubiquitin-binding protein yeast Rqt3, (human ASCC2), and Rqt4 (human TRIP4). The human complex has an additional component protein ASCC1 and can act as a transcriptional coactivator by interacting with transcription factors such as NF-kappa B." [PMID:12077347, PMID:28757607, PMID:32099016]	WAS	"A ribosome disassembly complex which dissociates stalled ribsome subunits as part of the ribosome quality control pathway. RQT complex is composed of a RNA helicase-family protein yeast Rqt2 (human ASCC3), a ubiquitin-binding protein yeast Rqt3, (human ASCC2), and Rqt4 (Human TRIP4)." [PMID:28757607, PMID:32099016]
	synonyms	"activating signal cointegrator 1 complex" EXACT [];"ASC-1 complex" EXACT [PMID:12077347];"RQT complex" EXACT []	WAS	"RQT complex" EXACT []

875 CROSS REFERENCES CHANGES
biological_process	GO:0000050	urea cycle
	xrefs	Reactome:R-HSA-70635 "Urea cycle";Wikipedia:Urea_cycle	WAS	Wikipedia:Urea_cycle
biological_process	GO:0000070	mitotic sister chromatid segregation
	xrefs	Reactome:R-HSA-2500257 "Resolution of Sister Chromatid Cohesion"	WAS	N/A
biological_process	GO:0000075	cell cycle checkpoint signaling
	xrefs	Reactome:R-HSA-69620 "Cell Cycle Checkpoints";Wikipedia:Cell_cycle_checkpoint	WAS	Wikipedia:Cell_cycle_checkpoint
biological_process	GO:0000080	mitotic G1 phase
	xrefs	Reactome:R-HSA-69236 "G1 Phase"	WAS	N/A
biological_process	GO:0000082	G1/S transition of mitotic cell cycle
	xrefs	Reactome:R-HSA-69206 "G1/S Transition"	WAS	N/A
biological_process	GO:0000086	G2/M transition of mitotic cell cycle
	xrefs	Reactome:R-HSA-69275 "G2/M Transition"	WAS	N/A
biological_process	GO:0000087	mitotic M phase
	xrefs	Reactome:R-HSA-68886 "M Phase"	WAS	N/A
biological_process	GO:0000096	sulfur amino acid metabolic process
	xrefs	Reactome:R-HSA-1614635 "Sulfur amino acid metabolism"	WAS	N/A
biological_process	GO:0000098	sulfur amino acid catabolic process
	xrefs	Reactome:R-HSA-1614558 "Degradation of cysteine and homocysteine"	WAS	N/A
biological_process	GO:0000122	negative regulation of transcription by RNA polymerase II
	xrefs	Reactome:R-HSA-2173795 "Downregulation of SMAD2/3:SMAD4 transcriptional activity";Reactome:R-HSA-8866904 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors"	WAS	N/A
biological_process	GO:0000154	rRNA modification
	xrefs	Reactome:R-HSA-6790901 "rRNA modification in the nucleus and cytosol";Reactome:R-HSA-6793080 "rRNA modification in the mitochondrion"	WAS	N/A
biological_process	GO:0000165	MAPK cascade
	xrefs	Reactome:R-HSA-169893 "Prolonged ERK activation events";Reactome:R-HSA-5673001 "RAF/MAP kinase cascade";Wikipedia:MAPK_cascade;Wikipedia:Mitogen-activated_protein_kinase	WAS	Wikipedia:MAPK_cascade;Wikipedia:Mitogen-activated_protein_kinase
biological_process	GO:0000183	rDNA heterochromatin formation
	xrefs	Reactome:R-HSA-427359 "SIRT1 negatively regulates rRNA expression";Reactome:R-HSA-427413 "NoRC negatively regulates rRNA expression"	WAS	N/A
biological_process	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
	xrefs	Reactome:R-HSA-927802 "Nonsense-Mediated Decay (NMD)";Wikipedia:Nonsense-mediated_decay;Wikipedia:Nonsense-mediated_mRNA_decay	WAS	Wikipedia:Nonsense-mediated_decay;Wikipedia:Nonsense-mediated_mRNA_decay
biological_process	GO:0000209	protein polyubiquitination
	xrefs	Reactome:R-HSA-983168 "Antigen processing	WAS	N/A
biological_process	GO:0000236	mitotic prometaphase
	xrefs	Reactome:R-HSA-68877 "Mitotic Prometaphase"	WAS	N/A
biological_process	GO:0000278	mitotic cell cycle
	xrefs	Reactome:R-HSA-69278 "Cell Cycle, Mitotic";Wikipedia:Mitosis	WAS	Wikipedia:Mitosis
biological_process	GO:0000281	mitotic cytokinesis
	xrefs	Reactome:R-HSA-68884 "Mitotic Telophase/Cytokinesis"	WAS	N/A
biological_process	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
	xrefs	Reactome:R-HSA-429914 "Deadenylation-dependent mRNA decay"	WAS	N/A
biological_process	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
	xrefs	Reactome:R-HSA-429947 "Deadenylation of mRNA"	WAS	N/A
biological_process	GO:0000387	spliceosomal snRNP assembly
	xrefs	Reactome:R-HSA-191859 "snRNP Assembly"	WAS	N/A
biological_process	GO:0000398	mRNA splicing, via spliceosome
	xrefs	Reactome:R-HSA-72163 "mRNA Splicing - Major Pathway";Reactome:R-HSA-72165 "mRNA Splicing - Minor Pathway"	WAS	N/A
biological_process	GO:0000423	mitophagy
	xrefs	Reactome:R-HSA-5205647 "Mitophagy";Wikipedia:Mitophagy	WAS	Wikipedia:Mitophagy
biological_process	GO:0000425	pexophagy
	xrefs	Reactome:R-HSA-9664873 "Pexophagy"	WAS	N/A
biological_process	GO:0000715	nucleotide-excision repair, DNA damage recognition
	xrefs	Reactome:R-HSA-5696394 "DNA Damage Recognition in GG-NER"	WAS	N/A
biological_process	GO:0000723	telomere maintenance
	xrefs	Reactome:R-HSA-157579 "Telomere Maintenance"	WAS	N/A
biological_process	GO:0000724	double-strand break repair via homologous recombination
	xrefs	Reactome:R-HSA-5693538 "Homology Directed Repair"	WAS	N/A
biological_process	GO:0000957	mitochondrial RNA catabolic process
	xrefs	Reactome:R-HSA-9836573 "Mitochondrial RNA degradation"	WAS	N/A
biological_process	GO:0001504	neurotransmitter uptake
	xrefs	Reactome:R-HSA-112313 "Neurotransmitter uptake and metabolism In glial cells"	WAS	N/A
biological_process	GO:0001523	retinoid metabolic process
	xrefs	Reactome:R-HSA-2187335 "The retinoid cycle in cones (daylight vision)";Reactome:R-HSA-2453902 "The canonical retinoid cycle in rods (twilight vision)";Reactome:R-HSA-975634 "Retinoid metabolism and transport"	WAS	N/A
biological_process	GO:0001561	fatty acid alpha-oxidation
	xrefs	MetaCyc:PWY-2501;Reactome:R-HSA-389599 "Alpha-oxidation of phytanate"	WAS	MetaCyc:PWY-2501
biological_process	GO:0001706	endoderm formation
	xrefs	Reactome:R-HSA-9823730 "Formation of definitive endoderm"	WAS	N/A
biological_process	GO:0001756	somitogenesis
	xrefs	Reactome:R-HSA-9824272 "Somitogenesis";Wikipedia:Somitogenesis	WAS	Wikipedia:Somitogenesis
biological_process	GO:0001822	kidney development
	xrefs	Reactome:R-HSA-9830369 "Kidney development";Wikipedia:Kidney_development	WAS	Wikipedia:Kidney_development
biological_process	GO:0001837	epithelial to mesenchymal transition
	xrefs	Reactome:R-HSA-9758919 "Epithelial-Mesenchymal Transition (EMT) during gastrulation"	WAS	N/A
biological_process	GO:0001867	complement activation, lectin pathway
	xrefs	Reactome:R-HSA-166662 "Lectin pathway of complement activation"	WAS	N/A
biological_process	GO:0001887	selenium compound metabolic process
	xrefs	Reactome:R-HSA-2408499 "Formation of selenosugars for excretion";Reactome:R-HSA-2408508 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";Reactome:R-HSA-2408550 "Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";Reactome:R-HSA-2408552 "Methylation of MeSeH for excretion";Reactome:R-HSA-5263617 "Metabolism of ingested MeSeO2H into MeSeH"	WAS	N/A
biological_process	GO:0001907	symbiont-mediated killing of host cell
	xrefs	Reactome:R-HSA-9637698 "Phagocyte cell death caused by cytosolic Mtb"	WAS	N/A
biological_process	GO:0001959	regulation of cytokine-mediated signaling pathway
	xrefs	Reactome:R-HSA-8939247 "RUNX1 regulates transcription of genes involved in interleukin signaling"	WAS	N/A
biological_process	GO:0002003	angiotensin maturation
	xrefs	Reactome:R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins"	WAS	N/A
biological_process	GO:0002223	stimulatory C-type lectin receptor signaling pathway
	xrefs	Reactome:R-HSA-5621481 "C-type lectin receptors (CLRs)"	WAS	N/A
biological_process	GO:0002224	toll-like receptor signaling pathway
	xrefs	Reactome:R-HSA-168898 "Toll-like Receptor Cascades"	WAS	N/A
biological_process	GO:0002250	adaptive immune response
	xrefs	Reactome:R-HSA-1280218 "Adaptive Immune System";Wikipedia:Adaptive_immune_system	WAS	Wikipedia:Adaptive_immune_system
biological_process	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
	xrefs	Reactome:R-HSA-983169 "Class I MHC mediated antigen processing & presentation"	WAS	N/A
biological_process	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
	xrefs	Reactome:R-HSA-1236973 "Cross-presentation of particulate exogenous antigens (phagosomes)";Reactome:R-HSA-1236974 "ER-Phagosome pathway";Reactome:R-HSA-1236978 "Cross-presentation of soluble exogenous antigens (endosomes)"	WAS	N/A
biological_process	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
	xrefs	Reactome:R-HSA-1236977 "Endosomal/Vacuolar pathway"	WAS	N/A
biological_process	GO:0002576	platelet degranulation
	xrefs	Reactome:R-HSA-114608 "Platelet degranulation"	WAS	N/A
biological_process	GO:0002753	cytoplasmic pattern recognition receptor signaling pathway
	xrefs	Reactome:R-HSA-9645460 "Alpha-protein kinase 1 signaling pathway"	WAS	N/A
biological_process	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
	xrefs	Reactome:R-HSA-166058 "MyD88:MAL(TIRAP) cascade initiated on plasma membrane";Reactome:R-HSA-975871 "MyD88 cascade initiated on plasma membrane"	WAS	N/A
biological_process	GO:0002756	MyD88-independent toll-like receptor signaling pathway
	xrefs	Reactome:R-HSA-166166 "MyD88-independent TLR4 cascade";Reactome:R-HSA-168927 "TICAM1, RIP1-mediated IKK complex recruitment"	WAS	N/A
biological_process	GO:0002862	negative regulation of inflammatory response to antigenic stimulus
	xrefs	Reactome:R-HSA-9660821 "ADORA2B mediated anti-inflammatory cytokines production";Reactome:R-HSA-9662834 "CD163 mediating an anti-inflammatory response";Reactome:R-HSA-9664323 "FCGR3A-mediated IL10 synthesis";Reactome:R-HSA-9664535 "LTC4-CYSLTR mediated IL4 production"	WAS	N/A
biological_process	GO:0003091	renal water homeostasis
	xrefs	Reactome:R-HSA-432040 "Vasopressin regulates renal water homeostasis via Aquaporins"	WAS	N/A
biological_process	GO:0003334	keratinocyte development
	xrefs	Reactome:R-HSA-9725554 "Differentiation of keratinocytes in interfollicular epidermis in mammalian skin"	WAS	N/A
biological_process	GO:0005975	carbohydrate metabolic process
	xrefs	Reactome:R-HSA-71387 "Metabolism of carbohydrates";Wikipedia:Carbohydrate_metabolism	WAS	Wikipedia:Carbohydrate_metabolism
biological_process	GO:0005977	glycogen metabolic process
	xrefs	Reactome:R-HSA-8982491 "Glycogen metabolism"	WAS	N/A
biological_process	GO:0005978	glycogen biosynthetic process
	xrefs	Reactome:R-HSA-3322077 "Glycogen synthesis"	WAS	N/A
biological_process	GO:0005980	glycogen catabolic process
	xrefs	Reactome:R-HSA-70221 "Glycogen breakdown (glycogenolysis)"	WAS	N/A
biological_process	GO:0005989	lactose biosynthetic process
	xrefs	Reactome:R-HSA-5653890 "Lactose synthesis"	WAS	N/A
biological_process	GO:0005999	xylulose biosynthetic process
	xrefs	Reactome:R-HSA-163754 "Insulin effects increased synthesis of Xylulose-5-Phosphate"	WAS	N/A
biological_process	GO:0006000	fructose metabolic process
	xrefs	Reactome:R-HSA-5652084 "Fructose metabolism";Wikipedia:Fructose	WAS	Wikipedia:Fructose
biological_process	GO:0006006	glucose metabolic process
	xrefs	Reactome:R-HSA-70326 "Glucose metabolism"	WAS	N/A
biological_process	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process
	xrefs	Reactome:R-HSA-73843 "5-Phosphoribose 1-diphosphate biosynthesis"	WAS	N/A
biological_process	GO:0006027	glycosaminoglycan catabolic process
	xrefs	Reactome:R-HSA-2024101 "CS/DS degradation"	WAS	N/A
biological_process	GO:0006048	UDP-N-acetylglucosamine biosynthetic process
	xrefs	Reactome:R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine"	WAS	N/A
biological_process	GO:0006068	ethanol catabolic process
	xrefs	Reactome:R-HSA-71384 "Ethanol oxidation"	WAS	N/A
biological_process	GO:0006086	acetyl-CoA biosynthetic process from pyruvate
	xrefs	MetaCyc:PYRUVDEHYD-PWY;Reactome:R-HSA-9861559 "PDH complex synthesizes acetyl-CoA from PYR"	WAS	MetaCyc:PYRUVDEHYD-PWY
biological_process	GO:0006090	pyruvate metabolic process
	xrefs	MetaCyc:P41-PWY;Reactome:R-HSA-70268 "Pyruvate metabolism";Wikipedia:Pyruvic_acid	WAS	MetaCyc:P41-PWY;Wikipedia:Pyruvic_acid
biological_process	GO:0006094	gluconeogenesis
	xrefs	Reactome:R-HSA-70263 "Gluconeogenesis";Wikipedia:Gluconeogenesis	WAS	Wikipedia:Gluconeogenesis
biological_process	GO:0006098	pentose-phosphate shunt
	xrefs	KEGG_PATHWAY:map00030;MetaCyc:PENTOSE-P-PWY;Reactome:R-HSA-71336 "Pentose phosphate pathway";Wikipedia:Pentose_phosphate_pathway	WAS	KEGG_PATHWAY:map00030;MetaCyc:PENTOSE-P-PWY;Wikipedia:Pentose_phosphate_pathway
biological_process	GO:0006099	tricarboxylic acid cycle
	xrefs	Reactome:R-HSA-71403 "Citric acid cycle (TCA cycle)";Wikipedia:Tricarboxylic_acid_cycle	WAS	Wikipedia:Tricarboxylic_acid_cycle
biological_process	GO:0006103	2-oxoglutarate metabolic process
	xrefs	Reactome:R-HSA-2978092 "Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate";Reactome:R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"	WAS	N/A
biological_process	GO:0006110	regulation of glycolytic process
	xrefs	Reactome:R-HSA-170822 "Regulation of Glucokinase by Glucokinase Regulatory Protein"	WAS	N/A
biological_process	GO:0006113	fermentation
	xrefs	MetaCyc:Fermentation;Wikipedia:Fermentation_(biochemistry)	WAS	MetaCyc:FERMENTATION-PWY;Wikipedia:Fermentation_(biochemistry)
biological_process	GO:0006124	ferredoxin metabolic process
	xrefs	Reactome:R-HSA-2395516 "Electron transport from NADPH to Ferredoxin"	WAS	N/A
biological_process	GO:0006195	purine nucleotide catabolic process
	xrefs	Reactome:R-HSA-74259 "Purine catabolism"	WAS	N/A
biological_process	GO:0006260	DNA replication
	xrefs	Reactome:R-HSA-176187 "Activation of ATR in response to replication stress";Reactome:R-HSA-69239 "Synthesis of DNA";Wikipedia:DNA_replication	WAS	Wikipedia:DNA_replication
biological_process	GO:0006261	DNA-templated DNA replication
	xrefs	Reactome:R-HSA-69306 "DNA Replication"	WAS	N/A
biological_process	GO:0006270	DNA replication initiation
	xrefs	Reactome:R-HSA-68952 "DNA replication initiation";Reactome:R-HSA-68962 "Activation of the pre-replicative complex"	WAS	N/A
biological_process	GO:0006271	DNA strand elongation involved in DNA replication
	xrefs	Reactome:R-HSA-69190 "DNA strand elongation"	WAS	N/A
biological_process	GO:0006278	RNA-templated DNA biosynthetic process
	xrefs	Reactome:R-HSA-162589 "Reverse Transcription of HIV RNA"	WAS	N/A
biological_process	GO:0006281	DNA repair
	xrefs	Reactome:R-HSA-73894 "DNA Repair";Wikipedia:DNA_repair	WAS	Wikipedia:DNA_repair
biological_process	GO:0006283	transcription-coupled nucleotide-excision repair
	xrefs	Reactome:R-HSA-6781827 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)"	WAS	N/A
biological_process	GO:0006284	base-excision repair
	xrefs	Reactome:R-HSA-73884 "Base Excision Repair";Reactome:R-HSA-73930 "Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";Wikipedia:Base_excision_repair	WAS	Wikipedia:Base_excision_repair
biological_process	GO:0006285	base-excision repair, AP site formation
	xrefs	Reactome:R-HSA-73929 "Base-Excision Repair, AP Site Formation"	WAS	N/A
biological_process	GO:0006287	base-excision repair, gap-filling
	xrefs	Reactome:R-HSA-73933 "Resolution of Abasic Sites (AP sites)"	WAS	N/A
biological_process	GO:0006289	nucleotide-excision repair
	xrefs	Reactome:R-HSA-5696398 "Nucleotide Excision Repair";Reactome:R-HSA-5696400 "Dual Incision in GG-NER"	WAS	N/A
biological_process	GO:0006297	nucleotide-excision repair, DNA gap filling
	xrefs	Reactome:R-HSA-5696397 "Gap-filling DNA repair synthesis and ligation in GG-NER"	WAS	N/A
biological_process	GO:0006298	mismatch repair
	xrefs	Reactome:R-HSA-5358508 "Mismatch Repair";Wikipedia:DNA_mismatch_repair	WAS	Wikipedia:DNA_mismatch_repair
biological_process	GO:0006302	double-strand break repair
	xrefs	Reactome:R-HSA-5693532 "DNA Double-Strand Break Repair"	WAS	N/A
biological_process	GO:0006303	double-strand break repair via nonhomologous end joining
	xrefs	Reactome:R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)"	WAS	N/A
biological_process	GO:0006307	DNA alkylation repair
	xrefs	Reactome:R-HSA-5657655 "MGMT-mediated DNA damage reversal";Reactome:R-HSA-73943 "Reversal of alkylation damage by DNA dioxygenases"	WAS	N/A
biological_process	GO:0006309	apoptotic DNA fragmentation
	xrefs	Reactome:R-HSA-140342 "Apoptosis induced DNA fragmentation"	WAS	N/A
biological_process	GO:0006325	chromatin organization
	xrefs	Reactome:R-HSA-4839726 "Chromatin organization"	WAS	N/A
biological_process	GO:0006334	nucleosome assembly
	xrefs	Reactome:R-HSA-774815 "Nucleosome assembly"	WAS	N/A
biological_process	GO:0006351	DNA-templated transcription
	xrefs	Reactome:R-HSA-2173793 "Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer";Reactome:R-HSA-74160 "Gene expression (Transcription)";Wikipedia:Transcription_(genetics)	WAS	Wikipedia:Transcription_(genetics)
biological_process	GO:0006355	regulation of DNA-templated transcription
	xrefs	Reactome:R-HSA-9013695 "NOTCH4 Intracellular Domain Regulates Transcription";Reactome:R-HSA-9762293 "Regulation of CDH11 gene transcription"	WAS	N/A
biological_process	GO:0006357	regulation of transcription by RNA polymerase II
	xrefs	Reactome:R-HSA-8864260 "Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors"	WAS	N/A
biological_process	GO:0006360	transcription by RNA polymerase I
	xrefs	Reactome:R-HSA-73864 "RNA Polymerase I Transcription"	WAS	N/A
biological_process	GO:0006361	transcription initiation at RNA polymerase I promoter
	xrefs	Reactome:R-HSA-73854 "RNA Polymerase I Promoter Clearance"	WAS	N/A
biological_process	GO:0006363	termination of RNA polymerase I transcription
	xrefs	Reactome:R-HSA-73863 "RNA Polymerase I Transcription Termination"	WAS	N/A
biological_process	GO:0006364	rRNA processing
	xrefs	Reactome:R-HSA-72312 "rRNA processing"	WAS	N/A
biological_process	GO:0006366	transcription by RNA polymerase II
	xrefs	Reactome:R-HSA-73857 "RNA Polymerase II Transcription"	WAS	N/A
biological_process	GO:0006367	transcription initiation at RNA polymerase II promoter
	xrefs	Reactome:R-HSA-167161 "HIV Transcription Initiation";Reactome:R-HSA-2032785 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";Reactome:R-HSA-350054 "Notch-HLH transcription pathway";Reactome:R-HSA-383280 "Nuclear Receptor transcription pathway";Reactome:R-HSA-73779 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";Reactome:R-HSA-75953 "RNA Polymerase II Transcription Initiation"	WAS	N/A
biological_process	GO:0006368	transcription elongation by RNA polymerase II
	xrefs	Reactome:R-HSA-167169 "HIV Transcription Elongation";Reactome:R-HSA-73776 "RNA Polymerase II Promoter Escape";Reactome:R-HSA-75955 "RNA Polymerase II Transcription Elongation"	WAS	N/A
biological_process	GO:0006369	termination of RNA polymerase II transcription
	xrefs	Reactome:R-HSA-73856 "RNA Polymerase II Transcription Termination"	WAS	N/A
biological_process	GO:0006370	7-methylguanosine mRNA capping
	xrefs	Reactome:R-HSA-72086 "mRNA Capping"	WAS	N/A
biological_process	GO:0006382	adenosine to inosine editing
	xrefs	Reactome:R-HSA-75064 "mRNA Editing	WAS	N/A
biological_process	GO:0006383	transcription by RNA polymerase III
	xrefs	Reactome:R-HSA-74158 "RNA Polymerase III Transcription"	WAS	N/A
biological_process	GO:0006385	transcription elongation by RNA polymerase III
	xrefs	Reactome:R-HSA-73780 "RNA Polymerase III Chain Elongation"	WAS	N/A
biological_process	GO:0006386	termination of RNA polymerase III transcription
	xrefs	Reactome:R-HSA-73980 "RNA Polymerase III Transcription Termination"	WAS	N/A
biological_process	GO:0006390	mitochondrial transcription
	xrefs	Reactome:R-HSA-75944 "Transcription from mitochondrial promoters"	WAS	N/A
biological_process	GO:0006391	transcription initiation at mitochondrial promoter
	xrefs	Reactome:R-HSA-163282 "Mitochondrial transcription initiation"	WAS	N/A
biological_process	GO:0006393	termination of mitochondrial transcription
	xrefs	Reactome:R-HSA-163316 "Mitochondrial transcription termination"	WAS	N/A
biological_process	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage
	xrefs	Reactome:R-HSA-77588 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	WAS	N/A
biological_process	GO:0006400	tRNA modification
	xrefs	Reactome:R-HSA-6782315 "tRNA modification in the nucleus and cytosol"	WAS	N/A
biological_process	GO:0006406	mRNA export from nucleus
	xrefs	Reactome:R-HSA-72202 "Transport of Mature Transcript to Cytoplasm"	WAS	N/A
biological_process	GO:0006412	translation
	xrefs	Reactome:R-HSA-72766 "Translation";Wikipedia:Translation_(genetics)	WAS	Wikipedia:Translation_(genetics)
biological_process	GO:0006413	translational initiation
	xrefs	Reactome:R-HSA-72613 "Eukaryotic Translation Initiation"	WAS	N/A
biological_process	GO:0006414	translational elongation
	xrefs	Reactome:R-HSA-156842 "Eukaryotic Translation Elongation"	WAS	N/A
biological_process	GO:0006415	translational termination
	xrefs	Reactome:R-HSA-72764 "Eukaryotic Translation Termination"	WAS	N/A
biological_process	GO:0006418	tRNA aminoacylation for protein translation
	xrefs	MetaCyc:TRNA-CHARGING-PWY;Reactome:R-HSA-379724 "tRNA Aminoacylation"	WAS	MetaCyc:TRNA-CHARGING-PWY
biological_process	GO:0006457	protein folding
	xrefs	Reactome:R-HSA-389960 "Formation of tubulin folding intermediates by CCT/TriC";Reactome:R-HSA-390466 "Chaperonin-mediated protein folding";Reactome:R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";Wikipedia:Protein_folding	WAS	Wikipedia:Protein_folding
biological_process	GO:0006465	signal peptide processing
	xrefs	Reactome:R-HSA-159782 "Removal of aminoterminal propeptides from gamma-carboxylated proteins"	WAS	N/A
biological_process	GO:0006479	protein methylation
	xrefs	Reactome:R-HSA-8876725 "Protein methylation"	WAS	N/A
biological_process	GO:0006488	dolichol-linked oligosaccharide biosynthetic process
	xrefs	Reactome:R-HSA-446193 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"	WAS	N/A
biological_process	GO:0006489	dolichyl diphosphate biosynthetic process
	xrefs	Reactome:R-HSA-446199 "Synthesis of Dolichyl-phosphate"	WAS	N/A
biological_process	GO:0006493	protein O-linked glycosylation
	xrefs	Reactome:R-HSA-5173105 "O-linked glycosylation";RESID:AA0153;RESID:AA0154;RESID:AA0155;RESID:AA0157;RESID:AA0212	WAS	RESID:AA0153;RESID:AA0154;RESID:AA0155;RESID:AA0157;RESID:AA0212
biological_process	GO:0006501	C-terminal protein lipidation
	xrefs	Reactome:R-HSA-163125 "Post-translational modification	WAS	N/A
biological_process	GO:0006506	GPI anchor biosynthetic process
	xrefs	Reactome:R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)"	WAS	N/A
biological_process	GO:0006518	peptide metabolic process
	xrefs	Reactome:R-HSA-2980736 "Peptide hormone metabolism"	WAS	N/A
biological_process	GO:0006521	regulation of amino acid metabolic process
	xrefs	Reactome:R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)"	WAS	N/A
biological_process	GO:0006546	glycine catabolic process
	xrefs	Reactome:R-HSA-6783984 "Glycine degradation"	WAS	N/A
biological_process	GO:0006548	L-histidine catabolic process
	xrefs	Reactome:R-HSA-70921 "Histidine catabolism"	WAS	N/A
biological_process	GO:0006554	lysine catabolic process
	xrefs	Reactome:R-HSA-71064 "Lysine catabolism"	WAS	N/A
biological_process	GO:0006558	L-phenylalanine metabolic process
	xrefs	Reactome:R-HSA-8964208 "Phenylalanine metabolism"	WAS	N/A
biological_process	GO:0006562	proline catabolic process
	xrefs	Reactome:R-HSA-70688 "Proline catabolism"	WAS	N/A
biological_process	GO:0006564	L-serine biosynthetic process
	xrefs	MetaCyc:SERSYN-PWY;Reactome:R-HSA-977347 "Serine biosynthesis"	WAS	MetaCyc:SERSYN-PWY
biological_process	GO:0006569	L-tryptophan catabolic process
	xrefs	Reactome:R-HSA-71240 "Tryptophan catabolism"	WAS	N/A
biological_process	GO:0006572	tyrosine catabolic process
	xrefs	Reactome:R-HSA-8963684 "Tyrosine catabolism"	WAS	N/A
biological_process	GO:0006590	thyroid hormone generation
	xrefs	Reactome:R-HSA-209968 "Thyroxine biosynthesis"	WAS	N/A
biological_process	GO:0006595	polyamine metabolic process
	xrefs	Reactome:R-HSA-351202 "Metabolism of polyamines"	WAS	N/A
biological_process	GO:0006596	polyamine biosynthetic process
	xrefs	Reactome:R-HSA-351200 "Interconversion of polyamines"	WAS	N/A
biological_process	GO:0006600	creatine metabolic process
	xrefs	Reactome:R-HSA-71288 "Creatine metabolism"	WAS	N/A
biological_process	GO:0006601	creatine biosynthetic process
	xrefs	MetaCyc:GLYCGREAT-PWY	WAS	N/A
biological_process	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
	xrefs	Reactome:R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane"	WAS	N/A
biological_process	GO:0006626	protein targeting to mitochondrion
	xrefs	Reactome:R-HSA-1268020 "Mitochondrial protein import"	WAS	N/A
biological_process	GO:0006629	lipid metabolic process
	xrefs	Reactome:R-HSA-556833 "Metabolism of lipids";Wikipedia:Lipid_metabolism	WAS	Wikipedia:Lipid_metabolism
biological_process	GO:0006631	fatty acid metabolic process
	xrefs	Reactome:R-HSA-211935 "Fatty acids";Reactome:R-HSA-434313 "Intracellular metabolism of fatty acids regulates insulin secretion";Reactome:R-HSA-8978868 "Fatty acid metabolism";Wikipedia:Fatty_acid_metabolism	WAS	Wikipedia:Fatty_acid_metabolism
biological_process	GO:0006635	fatty acid beta-oxidation
	xrefs	Reactome:R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation"	WAS	N/A
biological_process	GO:0006641	triglyceride metabolic process
	xrefs	Reactome:R-HSA-8979227 "Triglyceride metabolism"	WAS	N/A
biological_process	GO:0006644	phospholipid metabolic process
	xrefs	Reactome:R-HSA-1483115 "Hydrolysis of LPC";Reactome:R-HSA-1483152 "Hydrolysis of LPE";Reactome:R-HSA-1483257 "Phospholipid metabolism"	WAS	N/A
biological_process	GO:0006646	phosphatidylethanolamine biosynthetic process
	xrefs	Reactome:R-HSA-1483213 "Synthesis of PE"	WAS	N/A
biological_process	GO:0006654	phosphatidic acid biosynthetic process
	xrefs	Reactome:R-HSA-1483166 "Synthesis of PA"	WAS	N/A
biological_process	GO:0006655	phosphatidylglycerol biosynthetic process
	xrefs	Reactome:R-HSA-1483148 "Synthesis of PG"	WAS	N/A
biological_process	GO:0006656	phosphatidylcholine biosynthetic process
	xrefs	Reactome:R-HSA-1483191 "Synthesis of PC"	WAS	N/A
biological_process	GO:0006659	phosphatidylserine biosynthetic process
	xrefs	Reactome:R-HSA-1483101 "Synthesis of PS"	WAS	N/A
biological_process	GO:0006661	phosphatidylinositol biosynthetic process
	xrefs	Reactome:R-HSA-1483226 "Synthesis of PI";Reactome:R-HSA-1483248 "Synthesis of PIPs at the ER membrane";Reactome:R-HSA-1660499 "Synthesis of PIPs at the plasma membrane";Reactome:R-HSA-1660514 "Synthesis of PIPs at the Golgi membrane";Reactome:R-HSA-1660516 "Synthesis of PIPs at the early endosome membrane";Reactome:R-HSA-1660517 "Synthesis of PIPs at the late endosome membrane"	WAS	N/A
biological_process	GO:0006665	sphingolipid metabolic process
	xrefs	Reactome:R-HSA-428157 "Sphingolipid metabolism"	WAS	N/A
biological_process	GO:0006687	glycosphingolipid metabolic process
	xrefs	Reactome:R-HSA-1660662 "Glycosphingolipid metabolism"	WAS	N/A
biological_process	GO:0006688	glycosphingolipid biosynthetic process
	xrefs	Reactome:R-HSA-9840309 "Glycosphingolipid biosynthesis"	WAS	N/A
biological_process	GO:0006690	icosanoid metabolic process
	xrefs	Reactome:R-HSA-211979 "Eicosanoids"	WAS	N/A
biological_process	GO:0006691	leukotriene metabolic process
	xrefs	Reactome:R-HSA-2142691 "Synthesis of Leukotrienes (LT) and Eoxins (EX)"	WAS	N/A
biological_process	GO:0006692	prostanoid metabolic process
	xrefs	Reactome:R-HSA-140180 "COX reactions"	WAS	N/A
biological_process	GO:0006695	cholesterol biosynthetic process
	xrefs	Reactome:R-HSA-191273 "Cholesterol biosynthesis"	WAS	N/A
biological_process	GO:0006699	bile acid biosynthetic process
	xrefs	Reactome:R-HSA-192105 "Synthesis of bile acids and bile salts"	WAS	N/A
biological_process	GO:0006700	C21-steroid hormone biosynthetic process
	xrefs	Reactome:R-HSA-196108 "Pregnenolone biosynthesis"	WAS	N/A
biological_process	GO:0006702	androgen biosynthetic process
	xrefs	Reactome:R-HSA-193048 "Androgen biosynthesis"	WAS	N/A
biological_process	GO:0006703	estrogen biosynthetic process
	xrefs	Reactome:R-HSA-193144 "Estrogen biosynthesis"	WAS	N/A
biological_process	GO:0006704	glucocorticoid biosynthetic process
	xrefs	Reactome:R-HSA-194002 "Glucocorticoid biosynthesis"	WAS	N/A
biological_process	GO:0006705	mineralocorticoid biosynthetic process
	xrefs	Reactome:R-HSA-193993 "Mineralocorticoid biosynthesis"	WAS	N/A
biological_process	GO:0006740	NADPH regeneration
	xrefs	Reactome:R-HSA-389542 "NADPH regeneration"	WAS	N/A
biological_process	GO:0006744	ubiquinone biosynthetic process
	xrefs	MetaCyc:UBISYN-PWY;Reactome:R-HSA-2142789 "Ubiquinol biosynthesis"	WAS	MetaCyc:UBISYN-PWY
biological_process	GO:0006750	glutathione biosynthetic process
	xrefs	MetaCyc:GLUTATHIONESYN-PWY;Reactome:R-HSA-174403 "Glutathione synthesis and recycling"	WAS	MetaCyc:GLUTATHIONESYN-PWY
biological_process	GO:0006766	vitamin metabolic process
	xrefs	Reactome:R-HSA-211916 "Vitamins"	WAS	N/A
biological_process	GO:0006767	water-soluble vitamin metabolic process
	xrefs	Reactome:R-HSA-196849 "Metabolism of water-soluble vitamins and cofactors"	WAS	N/A
biological_process	GO:0006768	biotin metabolic process
	xrefs	Reactome:R-HSA-196780 "Biotin transport and metabolism";Wikipedia:Biotin	WAS	Wikipedia:Biotin
biological_process	GO:0006771	riboflavin metabolic process
	xrefs	Reactome:R-HSA-196843 "Vitamin B2 (riboflavin) metabolism";Wikipedia:Riboflavin	WAS	Wikipedia:Riboflavin
biological_process	GO:0006775	fat-soluble vitamin metabolic process
	xrefs	Reactome:R-HSA-6806667 "Metabolism of fat-soluble vitamins"	WAS	N/A
biological_process	GO:0006778	porphyrin-containing compound metabolic process
	xrefs	Reactome:R-HSA-189445 "Metabolism of porphyrins"	WAS	N/A
biological_process	GO:0006783	heme biosynthetic process
	xrefs	MetaCyc:HEMESYN2-PWY;Reactome:R-HSA-189451 "Heme biosynthesis"	WAS	MetaCyc:HEMESYN2-PWY
biological_process	GO:0006805	xenobiotic metabolic process
	xrefs	Reactome:R-HSA-211859 "Biological oxidations";Reactome:R-HSA-211981 "Xenobiotics";Reactome:R-HSA-2161541 "Abacavir metabolism";Reactome:R-HSA-9748784 "Drug ADME";Wikipedia:Drug_metabolism;Wikipedia:Xenobiotic_metabolism	WAS	Wikipedia:Drug_metabolism;Wikipedia:Xenobiotic_metabolism
biological_process	GO:0006810	transport
	xrefs	Reactome:R-HSA-382551 "Transport of small molecules"	WAS	N/A
biological_process	GO:0006811	monoatomic ion transport
	xrefs	Reactome:R-HSA-425393 "Transport of inorganic cations/anions and amino acids/oligopeptides"	WAS	N/A
biological_process	GO:0006833	water transport
	xrefs	Reactome:R-HSA-445717 "Aquaporin-mediated transport"	WAS	N/A
biological_process	GO:0006836	neurotransmitter transport
	xrefs	Reactome:R-HSA-181429 "Serotonin Neurotransmitter Release Cycle";Reactome:R-HSA-181430 "Norepinephrine Neurotransmitter Release Cycle";Reactome:R-HSA-210500 "Glutamate Neurotransmitter Release Cycle";Reactome:R-HSA-212676 "Dopamine Neurotransmitter Release Cycle";Reactome:R-HSA-264642 "Acetylcholine Neurotransmitter Release Cycle"	WAS	N/A
biological_process	GO:0006851	mitochondrial calcium ion transmembrane transport
	xrefs	Reactome:R-HSA-8949215 "Mitochondrial calcium ion transport"	WAS	N/A
biological_process	GO:0006853	carnitine shuttle
	xrefs	Reactome:R-HSA-200425 "Carnitine shuttle";Wikipedia:Carnitine#Role_in_fatty_acid_metabolism	WAS	Wikipedia:Carnitine#Role_in_fatty_acid_metabolism
biological_process	GO:0006865	amino acid transport
	xrefs	Reactome:R-HSA-352230 "Amino acid transport across the plasma membrane"	WAS	N/A
biological_process	GO:0006869	lipid transport
	xrefs	Reactome:R-HSA-1369062 "ABC transporters in lipid homeostasis"	WAS	N/A
biological_process	GO:0006879	intracellular iron ion homeostasis
	xrefs	Reactome:R-HSA-917937 "Iron uptake and transport"	WAS	N/A
biological_process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport
	xrefs	Reactome:R-HSA-159763 "Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus";Reactome:R-HSA-199977 "ER to Golgi Anterograde Transport"	WAS	N/A
biological_process	GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
	xrefs	Reactome:R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic"	WAS	N/A
biological_process	GO:0006892	post-Golgi vesicle-mediated transport
	xrefs	Reactome:R-HSA-199992 "trans-Golgi Network Vesicle Budding"	WAS	N/A
biological_process	GO:0006898	receptor-mediated endocytosis
	xrefs	Reactome:R-HSA-2173782 "Binding and Uptake of Ligands by Scavenger Receptors";Wikipedia:Receptor-mediated_endocytosis	WAS	Wikipedia:Receptor-mediated_endocytosis
biological_process	GO:0006909	phagocytosis
	xrefs	Reactome:R-HSA-9664417 "Leishmania phagocytosis";Wikipedia:Phagocytosis	WAS	Wikipedia:Phagocytosis
biological_process	GO:0006914	autophagy
	xrefs	Reactome:R-HSA-9612973 "Autophagy";Wikipedia:Autophagy_(cellular)	WAS	Wikipedia:Autophagy_(cellular)
biological_process	GO:0006915	apoptotic process
	xrefs	Reactome:R-HSA-109581 "Apoptosis";Wikipedia:Apoptosis	WAS	Wikipedia:Apoptosis
biological_process	GO:0006925	inflammatory cell apoptotic process
	xrefs	Reactome:R-HSA-168277 "Influenza Virus Induced Apoptosis"	WAS	N/A
biological_process	GO:0006936	muscle contraction
	xrefs	Reactome:R-HSA-445355 "Smooth Muscle Contraction";Wikipedia:Muscle_contraction	WAS	Wikipedia:Muscle_contraction
biological_process	GO:0006956	complement activation
	xrefs	Reactome:R-HSA-166658 "Complement cascade"	WAS	N/A
biological_process	GO:0006957	complement activation, alternative pathway
	xrefs	Reactome:R-HSA-173736 "Alternative complement activation"	WAS	N/A
biological_process	GO:0006958	complement activation, classical pathway
	xrefs	Reactome:R-HSA-173623 "Classical antibody-mediated complement activation"	WAS	N/A
biological_process	GO:0006996	organelle organization
	xrefs	Reactome:R-HSA-1852241 "Organelle biogenesis and maintenance"	WAS	N/A
biological_process	GO:0007004	telomere maintenance via telomerase
	xrefs	Reactome:R-HSA-171319 "Telomere Extension By Telomerase"	WAS	N/A
biological_process	GO:0007005	mitochondrion organization
	xrefs	Reactome:R-HSA-1592230 "Mitochondrial biogenesis"	WAS	N/A
biological_process	GO:0007018	microtubule-based movement
	xrefs	Reactome:R-HSA-983189 "Kinesins"	WAS	N/A
biological_process	GO:0007023	post-chaperonin tubulin folding pathway
	xrefs	Reactome:R-HSA-389977 "Post-chaperonin tubulin folding pathway"	WAS	N/A
biological_process	GO:0007049	cell cycle
	xrefs	Reactome:R-HSA-1640170 "Cell Cycle";Wikipedia:Cell_cycle	WAS	Wikipedia:Cell_cycle
biological_process	GO:0007052	mitotic spindle organization
	xrefs	Reactome:R-HSA-9648025 "EML4 and NUDC in mitotic spindle formation"	WAS	N/A
biological_process	GO:0007062	sister chromatid cohesion
	xrefs	Reactome:R-HSA-2468052 "Establishment of Sister Chromatid Cohesion"	WAS	N/A
biological_process	GO:0007076	mitotic chromosome condensation
	xrefs	Reactome:R-HSA-2299718 "Condensation of Prophase Chromosomes";Reactome:R-HSA-2514853 "Condensation of Prometaphase Chromosomes"	WAS	N/A
biological_process	GO:0007077	mitotic nuclear membrane disassembly
	xrefs	Reactome:R-HSA-2980766 "Nuclear Envelope Breakdown"	WAS	N/A
biological_process	GO:0007084	mitotic nuclear membrane reassembly
	xrefs	Reactome:R-HSA-2995410 "Nuclear Envelope (NE) Reassembly"	WAS	N/A
biological_process	GO:0007091	metaphase/anaphase transition of mitotic cell cycle
	xrefs	Reactome:R-HSA-68881 "Mitotic Metaphase/Anaphase Transition"	WAS	N/A
biological_process	GO:0007094	mitotic spindle assembly checkpoint signaling
	xrefs	Reactome:R-HSA-69618 "Mitotic Spindle Checkpoint"	WAS	N/A
biological_process	GO:0007096	regulation of exit from mitosis
	xrefs	Reactome:R-HSA-176409 "APC/C:Cdc20 mediated degradation of mitotic proteins"	WAS	N/A
biological_process	GO:0007165	signal transduction
	xrefs	Reactome:R-HSA-212718 "EGFR interacts with phospholipase C-gamma";Wikipedia:Signal_transduction	WAS	Wikipedia:Signal_transduction
biological_process	GO:0007166	cell surface receptor signaling pathway
	xrefs	Reactome:R-HSA-73887 "Death Receptor Signaling"	WAS	N/A
biological_process	GO:0007169	cell surface receptor protein tyrosine kinase signaling pathway
	xrefs	Reactome:R-HSA-187015 "Activation of TRKA receptors"	WAS	N/A
biological_process	GO:0007173	epidermal growth factor receptor signaling pathway
	xrefs	Reactome:R-HSA-177929 "Signaling by EGFR"	WAS	N/A
biological_process	GO:0007179	transforming growth factor beta receptor signaling pathway
	xrefs	Reactome:R-HSA-170834 "Signaling by TGF-beta Receptor Complex"	WAS	N/A
biological_process	GO:0007186	G protein-coupled receptor signaling pathway
	xrefs	Reactome:R-HSA-373076 "Class A/1 (Rhodopsin-like receptors)";Reactome:R-HSA-388396 "GPCR downstream signalling"	WAS	N/A
biological_process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway
	xrefs	Reactome:R-HSA-170660 "Adenylate cyclase activating pathway"	WAS	N/A
biological_process	GO:0007190	activation of adenylate cyclase activity
	xrefs	Reactome:R-HSA-187024 "NGF-independant TRKA activation"	WAS	N/A
biological_process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
	xrefs	Reactome:R-HSA-170670 "Adenylate cyclase inhibitory pathway"	WAS	N/A
biological_process	GO:0007219	Notch signaling pathway
	xrefs	Reactome:R-HSA-157118 "Signaling by NOTCH";Wikipedia:Notch_signaling_pathway	WAS	Wikipedia:Notch_signaling_pathway
biological_process	GO:0007221	positive regulation of transcription of Notch receptor target
	xrefs	Reactome:R-HSA-9013508 "NOTCH3 Intracellular Domain Regulates Transcription"	WAS	N/A
biological_process	GO:0007223	Wnt signaling pathway, calcium modulating pathway
	xrefs	Reactome:R-HSA-4086398 "Ca2+ pathway"	WAS	N/A
biological_process	GO:0007249	canonical NF-kappaB signal transduction
	xrefs	Reactome:R-HSA-5357956 "TNFR1-induced NF-kappa-B signaling pathway";Reactome:R-HSA-9014325 "TICAM1,TRAF6-dependent induction of TAK1 complex";Reactome:R-HSA-937072 "TRAF6-mediated induction of TAK1 complex within TLR4 complex"	WAS	N/A
biological_process	GO:0007254	JNK cascade
	xrefs	Reactome:R-HSA-450321 "JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1"	WAS	N/A
biological_process	GO:0007264	small GTPase-mediated signal transduction
	xrefs	Reactome:R-HSA-187706 "Signalling to p38 via RIT and RIN";Reactome:R-HSA-194315 "Signaling by Rho GTPases"	WAS	N/A
biological_process	GO:0007265	Ras protein signal transduction
	xrefs	Reactome:R-HSA-1169092 "Activation of RAS in B cells";Reactome:R-HSA-167044 "Signalling to RAS"	WAS	N/A
biological_process	GO:0007268	chemical synaptic transmission
	xrefs	Reactome:R-HSA-112316 "Neuronal System";Reactome:R-HSA-442720 "CREB1 phosphorylation through the activation of Adenylate Cyclase";Reactome:R-HSA-442729 "CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde";Reactome:R-HSA-442742 "CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";Reactome:R-HSA-451307 "Activation of Na-permeable kainate receptors";Reactome:R-HSA-451308 "Activation of Ca-permeable Kainate Receptor";Reactome:R-HSA-9619229 "Activation of RAC1 downstream of NMDARs";Reactome:R-HSA-9619483 "Activation of AMPK downstream of NMDARs";Reactome:R-HSA-9620244 "Long-term potentiation";Wikipedia:Neurotransmission	WAS	Wikipedia:Neurotransmission
biological_process	GO:0007269	neurotransmitter secretion
	xrefs	Reactome:R-HSA-112310 "Neurotransmitter release cycle"	WAS	N/A
biological_process	GO:0007281	germ cell development
	xrefs	Reactome:R-HSA-9827857 "Specification of primordial germ cells"	WAS	N/A
biological_process	GO:0007338	single fertilization
	xrefs	Reactome:R-HSA-1187000 "Fertilization"	WAS	N/A
biological_process	GO:0007340	acrosome reaction
	xrefs	Reactome:R-HSA-1300645 "Acrosome Reaction and Sperm:Oocyte Membrane Binding";Wikipedia:Acrosome_reaction	WAS	Wikipedia:Acrosome_reaction
biological_process	GO:0007346	regulation of mitotic cell cycle
	xrefs	Reactome:R-HSA-2465910 "MASTL Facilitates Mitotic Progression";Reactome:R-HSA-68911 "G2 Phase"	WAS	N/A
biological_process	GO:0007369	gastrulation
	xrefs	Reactome:R-HSA-9758941 "Gastrulation";Wikipedia:Gastrulation	WAS	Wikipedia:Gastrulation
biological_process	GO:0007399	nervous system development
	xrefs	Reactome:R-HSA-9675108 "Nervous system development"	WAS	N/A
biological_process	GO:0007411	axon guidance
	xrefs	Reactome:R-HSA-422475 "Axon guidance";Wikipedia:Axon_guidance	WAS	Wikipedia:Axon_guidance
biological_process	GO:0007586	digestion
	xrefs	Reactome:R-HSA-8935690 "Digestion";Wikipedia:Digestion	WAS	Wikipedia:Digestion
biological_process	GO:0007596	blood coagulation
	xrefs	Reactome:R-HSA-109582 "Hemostasis";Wikipedia:Coagulation	WAS	Wikipedia:Coagulation
biological_process	GO:0007597	blood coagulation, intrinsic pathway
	xrefs	Reactome:R-HSA-140837 "Intrinsic Pathway of Fibrin Clot Formation"	WAS	N/A
biological_process	GO:0007598	blood coagulation, extrinsic pathway
	xrefs	Reactome:R-HSA-140834 "Extrinsic Pathway of Fibrin Clot Formation"	WAS	N/A
biological_process	GO:0007600	sensory perception
	xrefs	Reactome:R-HSA-9709957 "Sensory Perception";Wikipedia:Perception	WAS	Wikipedia:Perception
biological_process	GO:0007603	phototransduction, visible light
	xrefs	Reactome:R-HSA-2187338 "Visual phototransduction"	WAS	N/A
biological_process	GO:0007605	sensory perception of sound
	xrefs	Reactome:R-HSA-9659379 "Sensory processing of sound";Wikipedia:Hearing_(sense)	WAS	Wikipedia:Hearing_(sense)
biological_process	GO:0007623	circadian rhythm
	xrefs	Reactome:R-HSA-400253 "Circadian Clock";Wikipedia:Circadian_rhythm	WAS	Wikipedia:Circadian_rhythm
biological_process	GO:0008033	tRNA processing
	xrefs	Reactome:R-HSA-72306 "tRNA processing"	WAS	N/A
biological_process	GO:0008104	protein localization
	xrefs	Reactome:R-HSA-9609507 "Protein localization"	WAS	N/A
biological_process	GO:0008152	metabolic process
	xrefs	Reactome:R-HSA-1430728 "Metabolism";Wikipedia:Metabolism	WAS	Wikipedia:Metabolism
biological_process	GO:0008202	steroid metabolic process
	xrefs	Reactome:R-HSA-8957322 "Metabolism of steroids";Wikipedia:Steroid_metabolism	WAS	Wikipedia:Steroid_metabolism
biological_process	GO:0008206	bile acid metabolic process
	xrefs	Reactome:R-HSA-194068 "Bile acid and bile salt metabolism"	WAS	N/A
biological_process	GO:0008286	insulin receptor signaling pathway
	xrefs	Reactome:R-HSA-74752 "Signaling by Insulin receptor"	WAS	N/A
biological_process	GO:0008380	RNA splicing
	xrefs	Reactome:R-HSA-72172 "mRNA Splicing";Wikipedia:RNA_splicing	WAS	Wikipedia:RNA_splicing
biological_process	GO:0008543	fibroblast growth factor receptor signaling pathway
	xrefs	Reactome:R-HSA-190236 "Signaling by FGFR"	WAS	N/A
biological_process	GO:0008584	male gonad development
	xrefs	Reactome:R-HSA-9690406 "Transcriptional regulation of testis differentiation"	WAS	N/A
biological_process	GO:0008611	ether lipid biosynthetic process
	xrefs	Reactome:R-HSA-75896 "Plasmalogen biosynthesis"	WAS	N/A
biological_process	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine
	xrefs	Reactome:R-HSA-204626 "Hypusine synthesis from eIF5A-lysine";RESID:AA0116	WAS	RESID:AA0116
biological_process	GO:0008645	hexose transmembrane transport
	xrefs	Reactome:R-HSA-189200 "Cellular hexose transport"	WAS	N/A
biological_process	GO:0009062	fatty acid catabolic process
	xrefs	Reactome:R-HSA-390918 "Peroxisomal lipid metabolism";Wikipedia:Fatty_acid_degradation	WAS	Wikipedia:Fatty_acid_degradation
biological_process	GO:0009064	glutamine family amino acid metabolic process
	xrefs	Reactome:R-HSA-8964539 "Glutamate and glutamine metabolism"	WAS	N/A
biological_process	GO:0009066	aspartate family amino acid metabolic process
	xrefs	Reactome:R-HSA-8963693 "Aspartate and asparagine metabolism"	WAS	N/A
biological_process	GO:0009072	aromatic amino acid metabolic process
	xrefs	Reactome:R-HSA-8963691 "Phenylalanine and tyrosine metabolism"	WAS	N/A
biological_process	GO:0009078	pyruvate family amino acid metabolic process
	xrefs	Reactome:R-HSA-8964540 "Alanine metabolism"	WAS	N/A
biological_process	GO:0009083	branched-chain amino acid catabolic process
	xrefs	Reactome:R-HSA-70895 "Branched-chain amino acid catabolism"	WAS	N/A
biological_process	GO:0009168	purine ribonucleoside monophosphate biosynthetic process
	xrefs	Reactome:R-HSA-73817 "Purine ribonucleoside monophosphate biosynthesis"	WAS	N/A
biological_process	GO:0009226	nucleotide-sugar biosynthetic process
	xrefs	Reactome:R-HSA-173599 "Formation of the active cofactor, UDP-glucuronate"	WAS	N/A
biological_process	GO:0009235	cobalamin metabolic process
	xrefs	Reactome:R-HSA-9759218 "Cobalamin (Cbl) metabolism"	WAS	N/A
biological_process	GO:0009249	protein lipoylation
	xrefs	Reactome:R-HSA-9857492 "Protein lipoylation"	WAS	N/A
biological_process	GO:0009267	cellular response to starvation
	xrefs	Reactome:R-HSA-9711097 "Cellular response to starvation"	WAS	N/A
biological_process	GO:0009298	GDP-mannose biosynthetic process
	xrefs	Reactome:R-HSA-446205 "Synthesis of GDP-mannose"	WAS	N/A
biological_process	GO:0009312	oligosaccharide biosynthetic process
	xrefs	Reactome:R-HSA-9033658 "Blood group systems biosynthesis"	WAS	N/A
biological_process	GO:0009313	oligosaccharide catabolic process
	xrefs	Reactome:R-HSA-8853383 "Lysosomal oligosaccharide catabolism"	WAS	N/A
biological_process	GO:0009449	gamma-aminobutyric acid biosynthetic process
	xrefs	Reactome:R-HSA-888568 "GABA synthesis"	WAS	N/A
biological_process	GO:0009450	gamma-aminobutyric acid catabolic process
	xrefs	MetaCyc:4AMINOBUTMETAB-PWY;Reactome:R-HSA-916853 "Degradation of GABA"	WAS	MetaCyc:4AMINOBUTMETAB-PWY
biological_process	GO:0009615	response to virus
	xrefs	Reactome:R-HSA-9824446 "Viral Infection Pathways"	WAS	N/A
biological_process	GO:0009617	response to bacterium
	xrefs	Reactome:R-HSA-9824439 "Bacterial Infection Pathways"	WAS	N/A
biological_process	GO:0009790	embryo development
	xrefs	Reactome:R-HSA-5619507 "Activation of HOX genes during differentiation";Wikipedia:Embryogenesis	WAS	Wikipedia:Embryogenesis
biological_process	GO:0009968	negative regulation of signal transduction
	xrefs	Reactome:R-HSA-8849472 "PTK6 Down-Regulation"	WAS	N/A
biological_process	GO:0010025	wax biosynthetic process
	xrefs	MetaCyc:PWY-282;Reactome:R-HSA-9640463 "Wax biosynthesis"	WAS	MetaCyc:PWY-282
biological_process	GO:0010038	response to metal ion
	xrefs	Reactome:R-HSA-5660526 "Response to metal ions"	WAS	N/A
biological_process	GO:0010142	farnesyl diphosphate biosynthetic process, mevalonate pathway
	xrefs	N/A	WAS	MetaCyc:PWY-922
biological_process	GO:0010389	regulation of G2/M transition of mitotic cell cycle
	xrefs	Reactome:R-HSA-8854518 "AURKA Activation by TPX2"	WAS	N/A
biological_process	GO:0010468	regulation of gene expression
	xrefs	Reactome:R-HSA-163767 "PP2A-mediated dephosphorylation of key metabolic factors";Reactome:R-HSA-9752946 "Expression and translocation of olfactory receptors";Wikipedia:Regulation_of_gene_expression	WAS	Wikipedia:Regulation_of_gene_expression
biological_process	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate
	xrefs	Reactome:R-HSA-204174 "Regulation of pyruvate dehydrogenase (PDH) complex"	WAS	N/A
biological_process	GO:0010586	miRNA metabolic process
	xrefs	Reactome:R-HSA-203927 "MicroRNA (miRNA) biogenesis"	WAS	N/A
biological_process	GO:0010737	protein kinase A signaling
	xrefs	Reactome:R-HSA-163358 "PKA-mediated phosphorylation of key metabolic factors"	WAS	N/A
biological_process	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway
	xrefs	Reactome:R-HSA-5357905 "Regulation of TNFR1 signaling"	WAS	N/A
biological_process	GO:0010999	regulation of eIF2 alpha phosphorylation by heme
	xrefs	Reactome:R-HSA-9648895 "Response of EIF2AK1 (HRI) to heme deficiency"	WAS	N/A
biological_process	GO:0012501	programmed cell death
	xrefs	Reactome:R-HSA-5357801 "Programmed Cell Death";Wikipedia:Programmed_cell_death	WAS	Wikipedia:Programmed_cell_death
biological_process	GO:0015012	heparan sulfate proteoglycan biosynthetic process
	xrefs	MetaCyc:PWY-6558;Reactome:R-HSA-2022928 "HS-GAG biosynthesis";RESID:AA0210	WAS	MetaCyc:PWY-6558;RESID:AA0210
biological_process	GO:0015671	oxygen transport
	xrefs	Reactome:R-HSA-8981607 "Intracellular oxygen transport"	WAS	N/A
biological_process	GO:0015701	bicarbonate transport
	xrefs	Reactome:R-HSA-1475029 "Reversible hydration of carbon dioxide";Reactome:R-HSA-1480926 "O2/CO2 exchange in erythrocytes";Reactome:R-HSA-425381 "Bicarbonate transporters"	WAS	N/A
biological_process	GO:0015721	bile acid and bile salt transport
	xrefs	Reactome:R-HSA-159418 "Recycling of bile acids and salts"	WAS	N/A
biological_process	GO:0015793	glycerol transmembrane transport
	xrefs	Reactome:R-HSA-432030 "Transport of glycerol from adipocytes to the liver by Aquaporins"	WAS	N/A
biological_process	GO:0015798	myo-inositol transport
	xrefs	Reactome:R-HSA-429593 "Inositol transporters"	WAS	N/A
biological_process	GO:0015889	cobalamin transport
	xrefs	Reactome:R-HSA-9758881 "Uptake of dietary cobalamins into enterocytes";Reactome:R-HSA-9758890 "Transport of RCbl within the body"	WAS	N/A
biological_process	GO:0015909	long-chain fatty acid transport
	xrefs	Reactome:R-HSA-804914 "Transport of fatty acids"	WAS	N/A
biological_process	GO:0015914	phospholipid transport
	xrefs	Reactome:R-HSA-1483196 "PI and PC transport between ER and Golgi membranes"	WAS	N/A
biological_process	GO:0015937	coenzyme A biosynthetic process
	xrefs	Reactome:R-HSA-196783 "Coenzyme A biosynthesis"	WAS	N/A
biological_process	GO:0015939	pantothenate metabolic process
	xrefs	Reactome:R-HSA-199220 "Vitamin B5 (pantothenate) metabolism"	WAS	N/A
biological_process	GO:0015949	nucleobase-containing small molecule interconversion
	xrefs	Reactome:R-HSA-499943 "Interconversion of nucleotide di- and triphosphates"	WAS	N/A
biological_process	GO:0016032	viral process
	xrefs	Reactome:R-HSA-162906 "HIV Infection";Wikipedia:Viral_life_cycle	WAS	Wikipedia:Viral_life_cycle
biological_process	GO:0016055	Wnt signaling pathway
	xrefs	Reactome:R-HSA-195721 "Signaling by WNT"	WAS	N/A
biological_process	GO:0016056	G protein-coupled opsin signaling pathway
	xrefs	Reactome:R-HSA-2514856 "The phototransduction cascade"	WAS	N/A
biological_process	GO:0016070	RNA metabolic process
	xrefs	Reactome:R-HSA-8953854 "Metabolism of RNA"	WAS	N/A
biological_process	GO:0016071	mRNA metabolic process
	xrefs	Reactome:R-HSA-111367 "SLBP independent Processing of Histone Pre-mRNAs"	WAS	N/A
biological_process	GO:0016078	tRNA decay
	xrefs	Reactome:R-HSA-9708296 "tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis"	WAS	N/A
biological_process	GO:0016125	sterol metabolic process
	xrefs	Reactome:R-HSA-211976 "Endogenous sterols"	WAS	N/A
biological_process	GO:0016197	endosomal transport
	xrefs	Reactome:R-HSA-917729 "Endosomal Sorting Complex Required For Transport (ESCRT)"	WAS	N/A
biological_process	GO:0016226	iron-sulfur cluster assembly
	xrefs	Reactome:R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis";Reactome:R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly"	WAS	N/A
biological_process	GO:0016236	macroautophagy
	xrefs	Reactome:R-HSA-1632852 "Macroautophagy";Reactome:R-HSA-5205685 "PINK1-PRKN Mediated Mitophagy";Reactome:R-HSA-8934903 "Receptor Mediated Mitophagy"	WAS	N/A
biological_process	GO:0016255	attachment of GPI anchor to protein
	xrefs	Reactome:R-HSA-162791 "Attachment of GPI anchor to uPAR"	WAS	N/A
biological_process	GO:0016259	selenocysteine metabolic process
	xrefs	Reactome:R-HSA-2408522 "Selenoamino acid metabolism"	WAS	N/A
biological_process	GO:0016264	gap junction assembly
	xrefs	Reactome:R-HSA-190861 "Gap junction assembly"	WAS	N/A
biological_process	GO:0016266	O-glycan processing
	xrefs	Reactome:R-HSA-913709 "O-linked glycosylation of mucins"	WAS	N/A
biological_process	GO:0016485	protein processing
	xrefs	Reactome:R-HSA-9033500 "TYSND1 cleaves peroxisomal proteins"	WAS	N/A
biological_process	GO:0016486	peptide hormone processing
	xrefs	Reactome:R-HSA-209952 "Peptide hormone biosynthesis";Reactome:R-HSA-400508 "Incretin synthesis, secretion, and inactivation";Reactome:R-HSA-422085 "Synthesis, secretion, and deacylation of Ghrelin"	WAS	N/A
biological_process	GO:0016554	cytidine to uridine editing
	xrefs	Reactome:R-HSA-72200 "mRNA Editing	WAS	N/A
biological_process	GO:0016556	mRNA modification
	xrefs	Reactome:R-HSA-75072 "mRNA Editing"	WAS	N/A
biological_process	GO:0016567	protein ubiquitination
	xrefs	Reactome:R-HSA-8852135 "Protein ubiquitination"	WAS	N/A
biological_process	GO:0016579	protein deubiquitination
	xrefs	Reactome:R-HSA-5688426 "Deubiquitination"	WAS	N/A
biological_process	GO:0016601	Rac protein signal transduction
	xrefs	Reactome:R-HSA-428540 "Activation of RAC1"	WAS	N/A
biological_process	GO:0016925	protein sumoylation
	xrefs	Reactome:R-HSA-2990846 "SUMOylation";Wikipedia:SUMO_protein	WAS	Wikipedia:SUMO_protein
biological_process	GO:0017183	protein histidyl modification to diphthamide
	xrefs	Reactome:R-HSA-5358493 "Synthesis of diphthamide-EEF2";RESID:AA0040	WAS	RESID:AA0040
biological_process	GO:0017187	peptidyl-glutamic acid carboxylation
	xrefs	Reactome:R-HSA-159854 "Gamma-carboxylation, transport, and amino-terminal cleavage of proteins";RESID:AA0032	WAS	RESID:AA0032
biological_process	GO:0018126	protein hydroxylation
	xrefs	Reactome:R-HSA-9629569 "Protein hydroxylation"	WAS	N/A
biological_process	GO:0018146	keratan sulfate biosynthetic process
	xrefs	Reactome:R-HSA-2022854 "Keratan sulfate biosynthesis";RESID:AA0247	WAS	RESID:AA0247
biological_process	GO:0018279	protein N-linked glycosylation via asparagine
	xrefs	Reactome:R-HSA-162699 "Synthesis of dolichyl-phosphate mannose";Reactome:R-HSA-446203 "Asparagine N-linked glycosylation";Reactome:R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose"	WAS	N/A
biological_process	GO:0018868	2-aminobenzenesulfonate metabolic process
	xrefs	N/A	WAS	UM-BBD_pathwayID:abs
biological_process	GO:0018873	atrazine metabolic process
	xrefs	N/A	WAS	UM-BBD_pathwayID:atr
biological_process	GO:0018874	benzoate metabolic process
	xrefs	UM-BBD_pathwayID:benz2	WAS	MetaCyc:P321-PWY;UM-BBD_pathwayID:benz2
biological_process	GO:0018875	anaerobic benzoate metabolic process
	xrefs	UM-BBD_pathwayID:benz	WAS	MetaCyc:CENTBENZCOA-PWY;UM-BBD_pathwayID:benz
biological_process	GO:0018882	(+)-camphor metabolic process
	xrefs	N/A	WAS	UM-BBD_pathwayID:cam
biological_process	GO:0018901	2,4-dichlorophenoxyacetic acid metabolic process
	xrefs	N/A	WAS	UM-BBD_pathwayID:2\,4-d
biological_process	GO:0018952	parathion metabolic process
	xrefs	N/A	WAS	UM-BBD_pathwayID:pthn
biological_process	GO:0019058	viral life cycle
	xrefs	Reactome:R-HSA-162588 "Budding and maturation of HIV virion";Reactome:R-HSA-168255 "Influenza Infection";Reactome:R-HSA-9609646 "HCMV Infection"	WAS	N/A
biological_process	GO:0019060	intracellular transport of viral protein in host cell
	xrefs	Reactome:R-HSA-168874 "Transport of HA trimer, NA tetramer and M2 tetramer from the endoplasmic reticulum to the Golgi Apparatus"	WAS	N/A
biological_process	GO:0019061	uncoating of virus
	xrefs	Reactome:R-HSA-162585 "Uncoating of the HIV Virion";Reactome:R-HSA-168336 "Uncoating of the Influenza Virion"	WAS	N/A
biological_process	GO:0019064	fusion of virus membrane with host plasma membrane
	xrefs	Reactome:R-HSA-168288 "Fusion of the Influenza Virion to the Host Cell Endosome";VZ:987 "Fusion of virus membrane with host cell membrane"	WAS	VZ:987 "Fusion of virus membrane with host cell membrane"
biological_process	GO:0019065	receptor-mediated endocytosis of virus by host cell
	xrefs	Reactome:R-HSA-168275 "Entry of Influenza Virion into Host Cell via Endocytosis"	WAS	N/A
biological_process	GO:0019068	virion assembly
	xrefs	Reactome:R-HSA-168302 "Budding";Reactome:R-HSA-168316 "Assembly of Viral Components at the Budding Site";Reactome:R-HSA-175474 "Assembly Of The HIV Virion"	WAS	N/A
biological_process	GO:0019070	viral genome maturation
	xrefs	Reactome:R-HSA-168330 "Viral RNP Complexes in the Host Cell Nucleus"	WAS	N/A
biological_process	GO:0019072	viral genome packaging
	xrefs	Reactome:R-HSA-168303 "Packaging of Eight RNA Segments"	WAS	N/A
biological_process	GO:0019076	viral release from host cell
	xrefs	Reactome:R-HSA-168298 "Release";VZ:1076 "Virus exit from host cell"	WAS	VZ:1076 "Virus exit from host cell"
biological_process	GO:0019081	viral translation
	xrefs	Reactome:R-HSA-9683701 "Translation of Structural Proteins";Reactome:R-HSA-9694635 "Translation of Structural Proteins";Reactome:R-HSA-9727281 "Translation of Accessory Proteins"	WAS	N/A
biological_process	GO:0019082	viral protein processing
	xrefs	Reactome:R-HSA-171286 "Synthesis and processing of ENV and VPU";Reactome:R-HSA-174495 "Synthesis And Processing Of GAG, GAGPOL Polyproteins";Reactome:R-HSA-9683610 "Maturation of nucleoprotein";Reactome:R-HSA-9683612 "Maturation of protein M";Reactome:R-HSA-9683673 "Maturation of protein 3a";Reactome:R-HSA-9683686 "Maturation of spike protein";Reactome:R-HSA-9694548 "Maturation of spike protein";Reactome:R-HSA-9694594 "Maturation of protein M";Reactome:R-HSA-9694631 "Maturation of nucleoprotein";Reactome:R-HSA-9694719 "Maturation of protein 3a"	WAS	N/A
biological_process	GO:0019083	viral transcription
	xrefs	Reactome:R-HSA-167172 "Transcription of the HIV genome";Reactome:R-HSA-168273 "Influenza Viral RNA Transcription and Replication"	WAS	N/A
biological_process	GO:0019216	regulation of lipid metabolic process
	xrefs	Reactome:R-HSA-2426168 "Activation of gene expression by SREBF (SREBP)";Reactome:R-HSA-400206 "Regulation of lipid metabolism by PPARalpha"	WAS	N/A
biological_process	GO:0019221	cytokine-mediated signaling pathway
	xrefs	Reactome:R-HSA-449147 "Signaling by Interleukins";Reactome:R-HSA-913531 "Interferon Signaling";Reactome:R-HSA-9607240 "FLT3 Signaling";Reactome:R-HSA-9674555 "Signaling by CSF3 (G-CSF)";Reactome:R-HSA-9680350 "Signaling by CSF1 (M-CSF) in myeloid cells"	WAS	N/A
biological_process	GO:0019222	regulation of metabolic process
	xrefs	Reactome:R-HSA-1989781 "PPARA activates gene expression"	WAS	N/A
biological_process	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway
	xrefs	MetaCyc:PWY-922	WAS	N/A
biological_process	GO:0019339	parathion catabolic process
	xrefs	MetaCyc:PARATHION-DEGRADATION-PWY;UM-BBD_pathwayID:pthn	WAS	MetaCyc:PARATHION-DEGRADATION-PWY
biological_process	GO:0019346	transsulfuration
	xrefs	MetaCyc:PWY-801;Reactome:R-HSA-1614603 "Cysteine formation from homocysteine";Wikipedia:Transsulfuration_pathway	WAS	MetaCyc:PWY-801;Wikipedia:Transsulfuration_pathway
biological_process	GO:0019369	arachidonate metabolic process
	xrefs	Reactome:R-HSA-2142753 "Arachidonate metabolism";Reactome:R-HSA-426048 "Arachidonate production from DAG";Wikipedia:Arachidonic_acid	WAS	Wikipedia:Arachidonic_acid
biological_process	GO:0019372	lipoxygenase pathway
	xrefs	Reactome:R-HSA-2142688 "Synthesis of 5-eicosatetraenoic acids";Reactome:R-HSA-2142712 "Synthesis of 12-eicosatetraenoic acid derivatives";Reactome:R-HSA-2142770 "Synthesis of 15-eicosatetraenoic acid derivatives";Reactome:R-HSA-9025094 "Biosynthesis of DPAn-3 SPMs"	WAS	N/A
biological_process	GO:0019373	epoxygenase P450 pathway
	xrefs	Reactome:R-HSA-2142670 "Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)"	WAS	N/A
biological_process	GO:0019381	atrazine catabolic process
	xrefs	MetaCyc:PWY-5724;UM-BBD_pathwayID:atr	WAS	MetaCyc:PWY-5724
biological_process	GO:0019383	(+)-camphor catabolic process
	xrefs	MetaCyc:P601-PWY;UM-BBD_pathwayID:cam	WAS	MetaCyc:P601-PWY
biological_process	GO:0019391	glucuronoside catabolic process
	xrefs	MetaCyc:GLUCUROCAT-PWY	WAS	N/A
biological_process	GO:0019432	triglyceride biosynthetic process
	xrefs	MetaCyc:TRIGLSYN-PWY;Reactome:R-HSA-75109 "Triglyceride biosynthesis"	WAS	MetaCyc:TRIGLSYN-PWY
biological_process	GO:0019433	triglyceride catabolic process
	xrefs	MetaCyc:LIPAS-PWY;Reactome:R-HSA-163560 "Triglyceride catabolism"	WAS	MetaCyc:LIPAS-PWY
biological_process	GO:0019490	2-aminobenzenesulfonate desulfonation
	xrefs	MetaCyc:2ASDEG-PWY;UM-BBD_pathwayID:abs	WAS	MetaCyc:2ASDEG-PWY
biological_process	GO:0019509	L-methionine salvage from methylthioadenosine
	xrefs	MetaCyc:PWY-4361;Reactome:R-HSA-1237112 "Methionine salvage pathway"	WAS	MetaCyc:PWY-4361
biological_process	GO:0019518	L-threonine catabolic process to glycine
	xrefs	MetaCyc:THREONINE-DEG2-PWY;Reactome:R-HSA-8849175 "Threonine catabolism"	WAS	MetaCyc:THREONINE-DEG2-PWY
biological_process	GO:0019538	protein metabolic process
	xrefs	Reactome:R-HSA-392499 "Metabolism of proteins";Wikipedia:Protein_metabolism	WAS	Wikipedia:Protein_metabolism
biological_process	GO:0019626	short-chain fatty acid catabolic process
	xrefs	MetaCyc:ACETOACETATE-DEG-PWY;Reactome:R-HSA-71032 "Propionyl-CoA catabolism"	WAS	MetaCyc:ACETOACETATE-DEG-PWY
biological_process	GO:0019640	D-glucuronate catabolic process to D-xylulose 5-phosphate
	xrefs	Reactome:R-HSA-5661270 "Formation of xylulose-5-phosphate"	WAS	N/A
biological_process	GO:0019664	mixed acid fermentation
	xrefs	MetaCyc:FERMENTATION-PWY;Wikipedia:Mixed_acid_fermentation	WAS	Wikipedia:Mixed_acid_fermentation
biological_process	GO:0019674	NAD metabolic process
	xrefs	Reactome:R-HSA-196807 "Nicotinate metabolism"	WAS	N/A
biological_process	GO:0019730	antimicrobial humoral response
	xrefs	Reactome:R-HSA-6803157 "Antimicrobial peptides"	WAS	N/A
biological_process	GO:0019752	carboxylic acid metabolic process
	xrefs	Reactome:R-HSA-389661 "Glyoxylate metabolism and glycine degradation"	WAS	N/A
biological_process	GO:0019852	L-ascorbic acid metabolic process
	xrefs	Reactome:R-HSA-196836 "Vitamin C (ascorbate) metabolism"	WAS	N/A
biological_process	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
	xrefs	Reactome:R-HSA-2132295 "MHC class II antigen presentation"	WAS	N/A
biological_process	GO:0019985	translesion synthesis
	xrefs	Reactome:R-HSA-73893 "DNA Damage Bypass"	WAS	N/A
biological_process	GO:0022400	regulation of opsin-mediated signaling pathway
	xrefs	Reactome:R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade"	WAS	N/A
biological_process	GO:0022617	extracellular matrix disassembly
	xrefs	Reactome:R-HSA-1474228 "Degradation of the extracellular matrix"	WAS	N/A
biological_process	GO:0022904	respiratory electron transport chain
	xrefs	Reactome:R-HSA-611105 "Respiratory electron transport";Wikipedia:Electron_transfer	WAS	Wikipedia:Electron_transfer
biological_process	GO:0030049	muscle filament sliding
	xrefs	Reactome:R-HSA-390522 "Striated Muscle Contraction"	WAS	N/A
biological_process	GO:0030070	insulin processing
	xrefs	Reactome:R-HSA-264876 "Insulin processing"	WAS	N/A
biological_process	GO:0030091	protein repair
	xrefs	Reactome:R-HSA-5676934 "Protein repair"	WAS	N/A
biological_process	GO:0030111	regulation of Wnt signaling pathway
	xrefs	Reactome:R-HSA-8939256 "RUNX1 regulates transcription of genes involved in WNT signaling"	WAS	N/A
biological_process	GO:0030148	sphingolipid biosynthetic process
	xrefs	MetaCyc:PWY-5129;Reactome:R-HSA-1660661 "Sphingolipid de novo biosynthesis"	WAS	MetaCyc:PWY-5129
biological_process	GO:0030149	sphingolipid catabolic process
	xrefs	Reactome:R-HSA-9845614 "Sphingolipid catabolism"	WAS	N/A
biological_process	GO:0030168	platelet activation
	xrefs	Reactome:R-HSA-392023 "Adrenaline signalling through Alpha-2 adrenergic receptor";Reactome:R-HSA-392170 "ADP signalling through P2Y purinoceptor 12";Reactome:R-HSA-418592 "ADP signalling through P2Y purinoceptor 1";Reactome:R-HSA-76002 "Platelet activation, signaling and aggregation"	WAS	N/A
biological_process	GO:0030198	extracellular matrix organization
	xrefs	Reactome:R-HSA-1474244 "Extracellular matrix organization"	WAS	N/A
biological_process	GO:0030199	collagen fibril organization
	xrefs	Reactome:R-HSA-1474290 "Collagen formation";Reactome:R-HSA-2214320 "Anchoring fibril formation";Reactome:R-HSA-2243919 "Crosslinking of collagen fibrils"	WAS	N/A
biological_process	GO:0030200	heparan sulfate proteoglycan catabolic process
	xrefs	Reactome:R-HSA-2024096 "HS-GAG degradation"	WAS	N/A
biological_process	GO:0030203	glycosaminoglycan metabolic process
	xrefs	Reactome:R-HSA-1630316 "Glycosaminoglycan metabolism"	WAS	N/A
biological_process	GO:0030204	chondroitin sulfate metabolic process
	xrefs	Reactome:R-HSA-1793185 "Chondroitin sulfate/dermatan sulfate metabolism"	WAS	N/A
biological_process	GO:0030206	chondroitin sulfate biosynthetic process
	xrefs	MetaCyc:PWY-6567;Reactome:R-HSA-2022870 "Chondroitin sulfate biosynthesis"	WAS	MetaCyc:PWY-6567
biological_process	GO:0030208	dermatan sulfate biosynthetic process
	xrefs	MetaCyc:PWY-6568;Reactome:R-HSA-2022923 "Dermatan sulfate biosynthesis"	WAS	MetaCyc:PWY-6568
biological_process	GO:0030212	hyaluronan metabolic process
	xrefs	Reactome:R-HSA-2142845 "Hyaluronan metabolism"	WAS	N/A
biological_process	GO:0030213	hyaluronan biosynthetic process
	xrefs	Reactome:R-HSA-2142850 "Hyaluronan biosynthesis and export"	WAS	N/A
biological_process	GO:0030214	hyaluronan catabolic process
	xrefs	MetaCyc:PWY-7645;Reactome:R-HSA-2160916 "Hyaluronan uptake and degradation"	WAS	MetaCyc:PWY-7645
biological_process	GO:0030422	siRNA processing
	xrefs	Reactome:R-HSA-426486 "Small interfering RNA (siRNA) biogenesis"	WAS	N/A
biological_process	GO:0030449	regulation of complement activation
	xrefs	Reactome:R-HSA-977606 "Regulation of Complement cascade"	WAS	N/A
biological_process	GO:0030509	BMP signaling pathway
	xrefs	Reactome:R-HSA-201451 "Signaling by BMP"	WAS	N/A
biological_process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
	xrefs	Reactome:R-HSA-2173788 "Downregulation of TGF-beta receptor signaling"	WAS	N/A
biological_process	GO:0030522	intracellular receptor signaling pathway
	xrefs	Reactome:R-HSA-9024446 "NR1H2 and NR1H3-mediated signaling"	WAS	N/A
biological_process	GO:0030574	collagen catabolic process
	xrefs	Reactome:R-HSA-1442490 "Collagen degradation"	WAS	N/A
biological_process	GO:0030851	granulocyte differentiation
	xrefs	Reactome:R-HSA-9616222 "Transcriptional regulation of granulopoiesis"	WAS	N/A
biological_process	GO:0030968	endoplasmic reticulum unfolded protein response
	xrefs	Reactome:R-HSA-381119 "Unfolded Protein Response (UPR)"	WAS	N/A
biological_process	GO:0031018	endocrine pancreas development
	xrefs	Reactome:R-HSA-186712 "Regulation of beta-cell development"	WAS	N/A
biological_process	GO:0031047	regulatory ncRNA-mediated gene silencing
	xrefs	Reactome:R-HSA-211000 "Gene Silencing by RNA"	WAS	N/A
biological_process	GO:0031124	mRNA 3'-end processing
	xrefs	Reactome:R-HSA-72187 "mRNA 3'-end processing";Reactome:R-HSA-75067 "Processing of Capped Intronless Pre-mRNA"	WAS	N/A
biological_process	GO:0031145	anaphase-promoting complex-dependent catabolic process
	xrefs	Reactome:R-HSA-174048 "APC/C:Cdc20 mediated degradation of Cyclin B";Reactome:R-HSA-174143 "APC/C-mediated degradation of cell cycle proteins";Reactome:R-HSA-174154 "APC/C:Cdc20 mediated degradation of Securin";Reactome:R-HSA-174184 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A"	WAS	N/A
biological_process	GO:0031293	membrane protein intracellular domain proteolysis
	xrefs	Reactome:R-HSA-193692 "Regulated proteolysis of p75NTR"	WAS	N/A
biological_process	GO:0031295	T cell costimulation
	xrefs	Reactome:R-HSA-388841 "Costimulation by the CD28 family"	WAS	N/A
biological_process	GO:0031342	negative regulation of cell killing
	xrefs	Reactome:R-HSA-9664433 "Leishmania parasite growth and survival"	WAS	N/A
biological_process	GO:0031343	positive regulation of cell killing
	xrefs	Reactome:R-HSA-9664420 "Killing mechanisms"	WAS	N/A
biological_process	GO:0031424	keratinization
	xrefs	Reactome:R-HSA-6805567 "Keratinization"	WAS	N/A
biological_process	GO:0031507	heterochromatin formation
	xrefs	Reactome:R-HSA-5334118 "DNA methylation"	WAS	N/A
biological_process	GO:0031581	hemidesmosome assembly
	xrefs	Reactome:R-HSA-446107 "Type I hemidesmosome assembly"	WAS	N/A
biological_process	GO:0032024	positive regulation of insulin secretion
	xrefs	Reactome:R-HSA-399997 "Acetylcholine regulates insulin secretion"	WAS	N/A
biological_process	GO:0032049	cardiolipin biosynthetic process
	xrefs	MetaCyc:PWY-5269;Reactome:R-HSA-1483076 "Synthesis of CL"	WAS	MetaCyc:PWY-5269
biological_process	GO:0032201	telomere maintenance via semi-conservative replication
	xrefs	Reactome:R-HSA-174417 "Telomere C-strand (Lagging Strand) Synthesis"	WAS	N/A
biological_process	GO:0032259	methylation
	xrefs	Reactome:R-HSA-156581 "Methylation";Wikipedia:Methylation	WAS	Wikipedia:Methylation
biological_process	GO:0032324	molybdopterin cofactor biosynthetic process
	xrefs	MetaCyc:Molybdenum-Cofactor-Biosynthesis;Reactome:R-HSA-947581 "Molybdenum cofactor biosynthesis"	WAS	MetaCyc:Molybdenum-Cofactor-Biosynthesis
biological_process	GO:0032455	nerve growth factor processing
	xrefs	Reactome:R-HSA-167060 "NGF processing"	WAS	N/A
biological_process	GO:0032479	regulation of type I interferon production
	xrefs	Reactome:R-HSA-3134975 "Regulation of innate immune responses to cytosolic DNA"	WAS	N/A
biological_process	GO:0032480	negative regulation of type I interferon production
	xrefs	Reactome:R-HSA-936440 "Negative regulators of DDX58/IFIH1 signaling"	WAS	N/A
biological_process	GO:0032481	positive regulation of type I interferon production
	xrefs	Reactome:R-HSA-1834949 "Cytosolic sensors of pathogen-associated DNA"	WAS	N/A
biological_process	GO:0032543	mitochondrial translation
	xrefs	Reactome:R-HSA-5368287 "Mitochondrial translation"	WAS	N/A
biological_process	GO:0032802	low-density lipoprotein particle receptor catabolic process
	xrefs	Reactome:R-HSA-8866427 "VLDLR internalisation and degradation"	WAS	N/A
biological_process	GO:0032981	mitochondrial respiratory chain complex I assembly
	xrefs	Reactome:R-HSA-6799198 "Complex I biogenesis"	WAS	N/A
biological_process	GO:0033146	regulation of intracellular estrogen receptor signaling pathway
	xrefs	Reactome:R-HSA-8931987 "RUNX1 regulates estrogen receptor mediated transcription"	WAS	N/A
biological_process	GO:0033209	tumor necrosis factor-mediated signaling pathway
	xrefs	Reactome:R-HSA-5668541 "TNFR2 non-canonical NF-kB pathway";Reactome:R-HSA-75893 "TNF signaling"	WAS	N/A
biological_process	GO:0033214	siderophore-dependent iron import into cell
	xrefs	Reactome:R-HSA-1222449 "Mtb iron assimilation by chelation"	WAS	N/A
biological_process	GO:0033271	myo-inositol phosphate transport
	xrefs	Reactome:R-HSA-1855156 "IPs transport between ER lumen and nucleus";Reactome:R-HSA-1855170 "IPs transport between nucleus and cytosol";Reactome:R-HSA-1855184 "IPs transport between cytosol and ER lumen";Reactome:R-HSA-1855192 "IPs transport between nucleus and ER lumen";Reactome:R-HSA-1855196 "IP3 and IP4 transport between cytosol and nucleus";Reactome:R-HSA-1855215 "IPs transport between ER lumen and cytosol";Reactome:R-HSA-1855229 "IP6 and IP7 transport between cytosol and nucleus"	WAS	N/A
biological_process	GO:0033387	putrescine biosynthetic process from arginine, via ornithine
	xrefs	MetaCyc:PWY-46	WAS	N/A
biological_process	GO:0033389	putrescine biosynthetic process from arginine, via agmatine
	xrefs	MetaCyc:PWY-40	WAS	N/A
biological_process	GO:0033390	putrescine biosynthetic process from arginine via N-carbamoylputrescine
	xrefs	MetaCyc:PWY-43	WAS	N/A
biological_process	GO:0033489	cholesterol biosynthetic process via desmosterol
	xrefs	MetaCyc:PWY66-4;Reactome:R-HSA-6807047 "Cholesterol biosynthesis via desmosterol"	WAS	MetaCyc:PWY66-4
biological_process	GO:0033490	cholesterol biosynthetic process via lathosterol
	xrefs	MetaCyc:PWY66-341;Reactome:R-HSA-6807062 "Cholesterol biosynthesis via lathosterol"	WAS	MetaCyc:PWY66-341
biological_process	GO:0033499	galactose catabolic process via UDP-galactose
	xrefs	MetaCyc:PWY-6317;Reactome:R-HSA-70370 "Galactose catabolism"	WAS	MetaCyc:PWY-6317
biological_process	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase
	xrefs	MetaCyc:PWY-5136;Reactome:R-HSA-389887 "Beta-oxidation of pristanoyl-CoA";Reactome:R-HSA-390247 "Beta-oxidation of very long chain fatty acids"	WAS	MetaCyc:PWY-5136
biological_process	GO:0033554	cellular response to stress
	xrefs	Reactome:R-HSA-2262752 "Cellular responses to stress"	WAS	N/A
biological_process	GO:0033559	unsaturated fatty acid metabolic process
	xrefs	Reactome:R-HSA-2046104 "alpha-linolenic (omega3) and linoleic (omega6) acid metabolism"	WAS	N/A
biological_process	GO:0033572	transferrin transport
	xrefs	Reactome:R-HSA-917977 "Transferrin endocytosis and recycling"	WAS	N/A
biological_process	GO:0033617	mitochondrial cytochrome c oxidase assembly
	xrefs	Reactome:R-HSA-9864848 "Complex IV assembly"	WAS	N/A
biological_process	GO:0033668	symbiont-mediated suppression of host apoptosis
	xrefs	Reactome:R-HSA-9635465 "Suppression of apoptosis"	WAS	N/A
biological_process	GO:0034080	CENP-A containing chromatin assembly
	xrefs	Reactome:R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere"	WAS	N/A
biological_process	GO:0034097	response to cytokine
	xrefs	Reactome:R-HSA-9645135 "STAT5 Activation"	WAS	N/A
biological_process	GO:0034110	regulation of homotypic cell-cell adhesion
	xrefs	Reactome:R-HSA-9759476 "Regulation of Homotypic Cell-Cell Adhesion"	WAS	N/A
biological_process	GO:0034121	regulation of toll-like receptor signaling pathway
	xrefs	Reactome:R-HSA-9860276 "SLC15A4:TASL-dependent IRF5 activation"	WAS	N/A
biological_process	GO:0034134	toll-like receptor 2 signaling pathway
	xrefs	Reactome:R-HSA-181438 "Toll Like Receptor 2 (TLR2) Cascade"	WAS	N/A
biological_process	GO:0034138	toll-like receptor 3 signaling pathway
	xrefs	Reactome:R-HSA-168164 "Toll Like Receptor 3 (TLR3) Cascade"	WAS	N/A
biological_process	GO:0034142	toll-like receptor 4 signaling pathway
	xrefs	Reactome:R-HSA-166016 "Toll Like Receptor 4 (TLR4) Cascade"	WAS	N/A
biological_process	GO:0034146	toll-like receptor 5 signaling pathway
	xrefs	Reactome:R-HSA-168176 "Toll Like Receptor 5 (TLR5) Cascade"	WAS	N/A
biological_process	GO:0034162	toll-like receptor 9 signaling pathway
	xrefs	Reactome:R-HSA-168138 "Toll Like Receptor 9 (TLR9) Cascade"	WAS	N/A
biological_process	GO:0034166	toll-like receptor 10 signaling pathway
	xrefs	Reactome:R-HSA-168142 "Toll Like Receptor 10 (TLR10) Cascade"	WAS	N/A
biological_process	GO:0034198	cellular response to amino acid starvation
	xrefs	Reactome:R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency";Reactome:R-HSA-9639288 "Amino acids regulate mTORC1"	WAS	N/A
biological_process	GO:0034199	activation of protein kinase A activity
	xrefs	Reactome:R-HSA-163615 "PKA activation"	WAS	N/A
biological_process	GO:0034220	monoatomic ion transmembrane transport
	xrefs	Reactome:R-HSA-983712 "Ion channel transport"	WAS	N/A
biological_process	GO:0034329	cell junction assembly
	xrefs	Reactome:R-HSA-446728 "Cell junction organization"	WAS	N/A
biological_process	GO:0034332	adherens junction organization
	xrefs	Reactome:R-HSA-418990 "Adherens junctions interactions"	WAS	N/A
biological_process	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway
	xrefs	Reactome:R-HSA-197264 "Nicotinamide salvaging"	WAS	N/A
biological_process	GO:0034369	plasma lipoprotein particle remodeling
	xrefs	Reactome:R-HSA-8963899 "Plasma lipoprotein remodeling"	WAS	N/A
biological_process	GO:0034371	chylomicron remodeling
	xrefs	Reactome:R-HSA-8963901 "Chylomicron remodeling"	WAS	N/A
biological_process	GO:0034374	low-density lipoprotein particle remodeling
	xrefs	Reactome:R-HSA-8964041 "LDL remodeling"	WAS	N/A
biological_process	GO:0034375	high-density lipoprotein particle remodeling
	xrefs	Reactome:R-HSA-8964058 "HDL remodeling"	WAS	N/A
biological_process	GO:0034377	plasma lipoprotein particle assembly
	xrefs	Reactome:R-HSA-8963898 "Plasma lipoprotein assembly"	WAS	N/A
biological_process	GO:0034378	chylomicron assembly
	xrefs	Reactome:R-HSA-8963888 "Chylomicron assembly"	WAS	N/A
biological_process	GO:0034379	very-low-density lipoprotein particle assembly
	xrefs	Reactome:R-HSA-8866423 "VLDL assembly"	WAS	N/A
biological_process	GO:0034380	high-density lipoprotein particle assembly
	xrefs	Reactome:R-HSA-8963896 "HDL assembly"	WAS	N/A
biological_process	GO:0034381	plasma lipoprotein particle clearance
	xrefs	Reactome:R-HSA-8964043 "Plasma lipoprotein clearance"	WAS	N/A
biological_process	GO:0034382	chylomicron remnant clearance
	xrefs	Reactome:R-HSA-8964026 "Chylomicron clearance"	WAS	N/A
biological_process	GO:0034383	low-density lipoprotein particle clearance
	xrefs	Reactome:R-HSA-8964038 "LDL clearance"	WAS	N/A
biological_process	GO:0034384	high-density lipoprotein particle clearance
	xrefs	Reactome:R-HSA-8964011 "HDL clearance"	WAS	N/A
biological_process	GO:0034389	lipid droplet organization
	xrefs	Reactome:R-HSA-8964572 "Lipid particle organization"	WAS	N/A
biological_process	GO:0034404	nucleobase-containing small molecule biosynthetic process
	xrefs	Reactome:R-HSA-8956320 "Nucleotide biosynthesis"	WAS	N/A
biological_process	GO:0034447	very-low-density lipoprotein particle clearance
	xrefs	Reactome:R-HSA-8964046 "VLDL clearance"	WAS	N/A
biological_process	GO:0034551	mitochondrial respiratory chain complex III assembly
	xrefs	Reactome:R-HSA-9865881 "Complex III assembly"	WAS	N/A
biological_process	GO:0034587	piRNA processing
	xrefs	Reactome:R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis"	WAS	N/A
biological_process	GO:0034599	cellular response to oxidative stress
	xrefs	Reactome:R-HSA-3299685 "Detoxification of Reactive Oxygen Species";Reactome:R-HSA-9707564 "Cytoprotection by HMOX1"	WAS	N/A
biological_process	GO:0034605	cellular response to heat
	xrefs	Reactome:R-HSA-3371556 "Cellular response to heat stress"	WAS	N/A
biological_process	GO:0034656	nucleobase-containing small molecule catabolic process
	xrefs	Reactome:R-HSA-8956319 "Nucleotide catabolism"	WAS	N/A
biological_process	GO:0035019	somatic stem cell population maintenance
	xrefs	Reactome:R-HSA-452723 "Transcriptional regulation of pluripotent stem cells"	WAS	N/A
biological_process	GO:0035036	sperm-egg recognition
	xrefs	Reactome:R-HSA-1300642 "Sperm Motility And Taxes";Reactome:R-HSA-2534343 "Interaction With Cumulus Cells And The Zona Pellucida"	WAS	N/A
biological_process	GO:0035194	regulatory ncRNA-mediated post-transcriptional gene silencing
	xrefs	Reactome:R-HSA-426496 "Post-transcriptional silencing by small RNAs";Wikipedia:RNA_interference	WAS	Wikipedia:RNA_interference
biological_process	GO:0035195	miRNA-mediated post-transcriptional gene silencing
	xrefs	Reactome:R-HSA-9759811 "Regulation of CDH11 mRNA translation by microRNAs"	WAS	N/A
biological_process	GO:0035329	hippo signaling
	xrefs	Reactome:R-HSA-2028269 "Signaling by Hippo"	WAS	N/A
biological_process	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
	xrefs	Reactome:R-HSA-75876 "Synthesis of very long-chain fatty acyl-CoAs"	WAS	N/A
biological_process	GO:0035567	non-canonical Wnt signaling pathway
	xrefs	Reactome:R-HSA-3858494 "Beta-catenin independent WNT signaling"	WAS	N/A
biological_process	GO:0035590	purinergic nucleotide receptor signaling pathway
	xrefs	Reactome:R-HSA-9660826 "Purinergic signaling in leishmaniasis infection"	WAS	N/A
biological_process	GO:0035627	ceramide transport
	xrefs	Reactome:R-HSA-9845576 "Glycosphingolipid transport"	WAS	N/A
biological_process	GO:0035655	interleukin-18-mediated signaling pathway
	xrefs	Reactome:R-HSA-9012546 "Interleukin-18 signaling"	WAS	N/A
biological_process	GO:0035666	TRIF-dependent toll-like receptor signaling pathway
	xrefs	Reactome:R-HSA-9013973 "TICAM1-dependent activation of IRF3/IRF7";Reactome:R-HSA-937061 "TRIF (TICAM1)-mediated TLR4 signaling"	WAS	N/A
biological_process	GO:0035694	mitochondrial protein catabolic process
	xrefs	Reactome:R-HSA-9837999 "Mitochondrial protein degradation"	WAS	N/A
biological_process	GO:0035722	interleukin-12-mediated signaling pathway
	xrefs	Reactome:R-HSA-447115 "Interleukin-12 family signaling"	WAS	N/A
biological_process	GO:0035723	interleukin-15-mediated signaling pathway
	xrefs	Reactome:R-HSA-8983432 "Interleukin-15 signaling"	WAS	N/A
biological_process	GO:0035735	intraciliary transport involved in cilium assembly
	xrefs	Reactome:R-HSA-5620924 "Intraflagellar transport"	WAS	N/A
biological_process	GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
	xrefs	Reactome:R-HSA-168643 "Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways"	WAS	N/A
biological_process	GO:0035965	cardiolipin acyl-chain remodeling
	xrefs	Reactome:R-HSA-1482798 "Acyl chain remodeling of CL"	WAS	N/A
biological_process	GO:0035973	aggrephagy
	xrefs	Reactome:R-HSA-9646399 "Aggrephagy"	WAS	N/A
biological_process	GO:0036066	protein O-linked fucosylation
	xrefs	Reactome:R-HSA-5173214 "O-glycosylation of TSR domain-containing proteins"	WAS	N/A
biological_process	GO:0036109	alpha-linolenic acid metabolic process
	xrefs	Reactome:R-HSA-2046106 "alpha-linolenic acid (ALA) metabolism";Wikipedia:Linoleic_acid	WAS	Wikipedia:Linoleic_acid
biological_process	GO:0036148	phosphatidylglycerol acyl-chain remodeling
	xrefs	Reactome:R-HSA-1482925 "Acyl chain remodelling of PG"	WAS	N/A
biological_process	GO:0036149	phosphatidylinositol acyl-chain remodeling
	xrefs	Reactome:R-HSA-1482922 "Acyl chain remodelling of PI"	WAS	N/A
biological_process	GO:0036150	phosphatidylserine acyl-chain remodeling
	xrefs	Reactome:R-HSA-1482801 "Acyl chain remodelling of PS"	WAS	N/A
biological_process	GO:0036151	phosphatidylcholine acyl-chain remodeling
	xrefs	Reactome:R-HSA-1482788 "Acyl chain remodelling of PC"	WAS	N/A
biological_process	GO:0036152	phosphatidylethanolamine acyl-chain remodeling
	xrefs	Reactome:R-HSA-1482839 "Acyl chain remodelling of PE"	WAS	N/A
biological_process	GO:0036155	acylglycerol acyl-chain remodeling
	xrefs	Reactome:R-HSA-1482883 "Acyl chain remodeling of DAG and TAG"	WAS	N/A
biological_process	GO:0036297	interstrand cross-link repair
	xrefs	Reactome:R-HSA-6783310 "Fanconi Anemia Pathway"	WAS	N/A
biological_process	GO:0036388	pre-replicative complex assembly
	xrefs	Reactome:R-HSA-68867 "Assembly of the pre-replicative complex"	WAS	N/A
biological_process	GO:0036498	IRE1-mediated unfolded protein response
	xrefs	Reactome:R-HSA-381070 "IRE1alpha activates chaperones"	WAS	N/A
biological_process	GO:0036499	PERK-mediated unfolded protein response
	xrefs	Reactome:R-HSA-381042 "PERK regulates gene expression"	WAS	N/A
biological_process	GO:0036500	ATF6-mediated unfolded protein response
	xrefs	Reactome:R-HSA-381033 "ATF6 (ATF6-alpha) activates chaperones"	WAS	N/A
biological_process	GO:0038020	insulin receptor recycling
	xrefs	Reactome:R-HSA-77387 "Insulin receptor recycling"	WAS	N/A
biological_process	GO:0038061	non-canonical NF-kappaB signal transduction
	xrefs	Reactome:R-HSA-5676590 "NIK-->noncanonical NF-kB signaling"	WAS	N/A
biological_process	GO:0038066	p38MAPK cascade
	xrefs	Reactome:R-HSA-450302 "activated TAK1 mediates p38 MAPK activation"	WAS	N/A
biological_process	GO:0038095	Fc-epsilon receptor signaling pathway
	xrefs	Reactome:R-HSA-2454202 "Fc epsilon receptor (FCERI) signaling"	WAS	N/A
biological_process	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
	xrefs	Reactome:R-HSA-2029480 "Fcgamma receptor (FCGR) dependent phagocytosis";Reactome:R-HSA-9664422 "FCGR3A-mediated phagocytosis"	WAS	N/A
biological_process	GO:0038110	interleukin-2-mediated signaling pathway
	xrefs	Reactome:R-HSA-9020558 "Interleukin-2 signaling"	WAS	N/A
biological_process	GO:0038111	interleukin-7-mediated signaling pathway
	xrefs	Reactome:R-HSA-1266695 "Interleukin-7 signaling"	WAS	N/A
biological_process	GO:0038113	interleukin-9-mediated signaling pathway
	xrefs	Reactome:R-HSA-8985947 "Interleukin-9 signaling"	WAS	N/A
biological_process	GO:0038114	interleukin-21-mediated signaling pathway
	xrefs	Reactome:R-HSA-9020958 "Interleukin-21 signaling"	WAS	N/A
biological_process	GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway
	xrefs	Reactome:R-HSA-168179 "Toll Like Receptor TLR1:TLR2 Cascade"	WAS	N/A
biological_process	GO:0038124	toll-like receptor TLR6:TLR2 signaling pathway
	xrefs	Reactome:R-HSA-168188 "Toll Like Receptor TLR6:TLR2 Cascade"	WAS	N/A
biological_process	GO:0038128	ERBB2 signaling pathway
	xrefs	Reactome:R-HSA-1227986 "Signaling by ERBB2"	WAS	N/A
biological_process	GO:0038155	interleukin-23-mediated signaling pathway
	xrefs	Reactome:R-HSA-9020933 "Interleukin-23 signaling"	WAS	N/A
biological_process	GO:0038162	erythropoietin-mediated signaling pathway
	xrefs	Reactome:R-HSA-9006335 "Signaling by Erythropoietin"	WAS	N/A
biological_process	GO:0038172	interleukin-33-mediated signaling pathway
	xrefs	Reactome:R-HSA-9014843 "Interleukin-33 signaling"	WAS	N/A
biological_process	GO:0039524	symbiont-mediated suppression of host mRNA processing
	xrefs	Reactome:R-HSA-168315 "Inhibition of Host mRNA Processing and RNA Silencing";VZ:903 "Inhibition of host pre-mRNA processing by virus"	WAS	VZ:903 "Inhibition of host pre-mRNA processing by virus"
biological_process	GO:0039585	PKR/eIFalpha signaling
	xrefs	Reactome:R-HSA-9833482 "PKR-mediated signaling"	WAS	N/A
biological_process	GO:0039587	symbiont-mediated-mediated suppression of host tetherin activity
	xrefs	VZ:665	WAS	N/A
biological_process	GO:0039673	symbiont-mediated suppression of host dendritic cell mediated immune response
	xrefs	VZ:869	WAS	N/A
biological_process	GO:0040029	epigenetic regulation of gene expression
	xrefs	Reactome:R-HSA-212165 "Epigenetic regulation of gene expression";Reactome:R-HSA-8986944 "Transcriptional Regulation by MECP2"	WAS	N/A
biological_process	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
	xrefs	Reactome:R-HSA-182971 "EGFR downregulation"	WAS	N/A
biological_process	GO:0042167	heme catabolic process
	xrefs	Reactome:R-HSA-189483 "Heme degradation"	WAS	N/A
biological_process	GO:0042168	heme metabolic process
	xrefs	Reactome:R-HSA-9707616 "Heme signaling"	WAS	N/A
biological_process	GO:0042203	toluene catabolic process
	xrefs	UM-BBD_pathwayID:tol	WAS	N/A
biological_process	GO:0042276	error-prone translesion synthesis
	xrefs	Reactome:R-HSA-110312 "Translesion synthesis by REV1";Reactome:R-HSA-5655862 "Translesion synthesis by POLK";Reactome:R-HSA-5656121 "Translesion synthesis by POLI"	WAS	N/A
biological_process	GO:0042304	regulation of fatty acid biosynthetic process
	xrefs	Reactome:R-HSA-163680 "AMPK inhibits chREBP transcriptional activation activity"	WAS	N/A
biological_process	GO:0042339	keratan sulfate metabolic process
	xrefs	Reactome:R-HSA-1638074 "Keratan sulfate/keratin metabolism"	WAS	N/A
biological_process	GO:0042340	keratan sulfate catabolic process
	xrefs	Reactome:R-HSA-2022857 "Keratan sulfate degradation"	WAS	N/A
biological_process	GO:0042350	GDP-L-fucose biosynthetic process
	xrefs	Reactome:R-HSA-6787639 "GDP-fucose biosynthesis"	WAS	N/A
biological_process	GO:0042359	vitamin D metabolic process
	xrefs	Reactome:R-HSA-196791 "Vitamin D (calciferol) metabolism"	WAS	N/A
biological_process	GO:0042360	vitamin E metabolic process
	xrefs	Reactome:R-HSA-8877627 "Vitamin E"	WAS	N/A
biological_process	GO:0042373	vitamin K metabolic process
	xrefs	Reactome:R-HSA-6806664 "Metabolism of vitamin K"	WAS	N/A
biological_process	GO:0042403	thyroid hormone metabolic process
	xrefs	Reactome:R-HSA-350864 "Regulation of thyroid hormone activity"	WAS	N/A
biological_process	GO:0042407	cristae formation
	xrefs	Reactome:R-HSA-8949613 "Cristae formation"	WAS	N/A
biological_process	GO:0042420	dopamine catabolic process
	xrefs	Reactome:R-HSA-379397 "Enzymatic degradation of dopamine by COMT";Reactome:R-HSA-379398 "Enzymatic degradation of Dopamine by monoamine oxidase"	WAS	N/A
biological_process	GO:0042423	catecholamine biosynthetic process
	xrefs	Reactome:R-HSA-209905 "Catecholamine biosynthesis";Wikipedia:Catecholamines	WAS	Wikipedia:Catecholamines
biological_process	GO:0042426	choline catabolic process
	xrefs	Reactome:R-HSA-6798163 "Choline catabolism"	WAS	N/A
biological_process	GO:0042429	serotonin catabolic process
	xrefs	Reactome:R-HSA-380612 "Metabolism of serotonin"	WAS	N/A
biological_process	GO:0042438	melanin biosynthetic process
	xrefs	Reactome:R-HSA-5662702 "Melanin biosynthesis"	WAS	N/A
biological_process	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I
	xrefs	Reactome:R-HSA-1236975 "Antigen processing-Cross presentation"	WAS	N/A
biological_process	GO:0042723	thiamine-containing compound metabolic process
	xrefs	Reactome:R-HSA-196819 "Vitamin B1 (thiamin) metabolism"	WAS	N/A
biological_process	GO:0042730	fibrinolysis
	xrefs	Reactome:R-HSA-75205 "Dissolution of Fibrin Clot";Wikipedia:Fibrinolysis	WAS	Wikipedia:Fibrinolysis
biological_process	GO:0042759	long-chain fatty acid biosynthetic process
	xrefs	Reactome:R-HSA-9018677 "Biosynthesis of DHA-derived SPMs";Reactome:R-HSA-9018679 "Biosynthesis of EPA-derived SPMs";Reactome:R-HSA-9018683 "Biosynthesis of DPA-derived SPMs";Reactome:R-HSA-9026403 "Biosynthesis of DPAn-3-derived 13-series resolvins";Reactome:R-HSA-9027604 "Biosynthesis of electrophilic -3 PUFA oxo-derivatives"	WAS	N/A
biological_process	GO:0042776	proton motive force-driven mitochondrial ATP synthesis
	xrefs	Reactome:R-HSA-163210 "Formation of ATP by chemiosmotic coupling"	WAS	N/A
biological_process	GO:0042795	snRNA transcription by RNA polymerase II
	xrefs	Reactome:R-HSA-6807505 "RNA polymerase II transcribes snRNA genes"	WAS	N/A
biological_process	GO:0042816	vitamin B6 metabolic process
	xrefs	Reactome:R-HSA-964975 "Vitamin B6 activation to pyridoxal phosphate"	WAS	N/A
biological_process	GO:0042981	regulation of apoptotic process
	xrefs	Reactome:R-HSA-169911 "Regulation of Apoptosis";Reactome:R-HSA-5633008 "TP53 Regulates Transcription of Cell Death Genes"	WAS	N/A
biological_process	GO:0043043	peptide biosynthetic process
	xrefs	Reactome:R-HSA-9037628 "Rhesus blood group biosynthesis"	WAS	N/A
biological_process	GO:0043065	positive regulation of apoptotic process
	xrefs	Reactome:R-HSA-193648 "NRAGE signals death through JNK";Reactome:R-HSA-205043 "NRIF signals cell death from the nucleus"	WAS	N/A
biological_process	GO:0043066	negative regulation of apoptotic process
	xrefs	Reactome:R-HSA-193639 "p75NTR signals via NF-kB";Reactome:R-HSA-211728 "Regulation of PAK-2p34 activity by PS-GAP/RHG10";Reactome:R-HSA-211733 "Regulation of activated PAK-2p34 by proteasome mediated degradation"	WAS	N/A
biological_process	GO:0043097	pyrimidine nucleoside salvage
	xrefs	Reactome:R-HSA-73614 "Pyrimidine salvage"	WAS	N/A
biological_process	GO:0043101	purine-containing compound salvage
	xrefs	Reactome:R-HSA-74217 "Purine salvage"	WAS	N/A
biological_process	GO:0043123	positive regulation of canonical NF-kappaB signal transduction
	xrefs	Reactome:R-HSA-937039 "IRAK1 recruits IKK complex"	WAS	N/A
biological_process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
	xrefs	Reactome:R-HSA-75815 "Ubiquitin-dependent degradation of Cyclin D"	WAS	N/A
biological_process	GO:0043173	nucleotide salvage
	xrefs	Reactome:R-HSA-8956321 "Nucleotide salvage";Wikipedia:Nucleotide_salvage	WAS	Wikipedia:Nucleotide_salvage
biological_process	GO:0043248	proteasome assembly
	xrefs	Reactome:R-HSA-9907900 "Proteasome assembly"	WAS	N/A
biological_process	GO:0043252	sodium-independent organic anion transport
	xrefs	Reactome:R-HSA-879518 "Transport of organic anions"	WAS	N/A
biological_process	GO:0043312	neutrophil degranulation
	xrefs	Reactome:R-HSA-6798695 "Neutrophil degranulation"	WAS	N/A
biological_process	GO:0043467	regulation of generation of precursor metabolites and energy
	xrefs	Reactome:R-HSA-163685 "Integration of energy metabolism"	WAS	N/A
biological_process	GO:0043488	regulation of mRNA stability
	xrefs	Reactome:R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA";Reactome:R-HSA-450531 "Regulation of mRNA stability by proteins that bind AU-rich elements"	WAS	N/A
biological_process	GO:0043490	malate-aspartate shuttle
	xrefs	MetaCyc:MALATE-ASPARTATE-SHUTTLE-PWY;Reactome:R-HSA-9856872 "Malate-aspartate shuttle";Wikipedia:Malate-aspartate_shuttle	WAS	Wikipedia:Malate-aspartate_shuttle
biological_process	GO:0043491	phosphatidylinositol 3-kinase/protein kinase B signal transduction
	xrefs	Reactome:R-HSA-198203 "PI3K/AKT activation";Reactome:R-HSA-198323 "AKT phosphorylates targets in the cytosol";Reactome:R-HSA-198693 "AKT phosphorylates targets in the nucleus"	WAS	N/A
biological_process	GO:0043647	inositol phosphate metabolic process
	xrefs	Reactome:R-HSA-1483249 "Inositol phosphate metabolism"	WAS	N/A
biological_process	GO:0043651	linoleic acid metabolic process
	xrefs	Reactome:R-HSA-2046105 "Linoleic acid (LA) metabolism";Wikipedia:Linoleic_acid	WAS	Wikipedia:Linoleic_acid
biological_process	GO:0043687	post-translational protein modification
	xrefs	Reactome:R-HSA-597592 "Post-translational protein modification";Wikipedia:Posttranslational_modification	WAS	Wikipedia:Posttranslational_modification
biological_process	GO:0044003	symbiont-mediated perturbation of host process
	xrefs	Reactome:R-HSA-9635644 "Inhibition of membrane repair";Reactome:R-HSA-9636667 "Manipulation of host energy metabolism"	WAS	N/A
biological_process	GO:0044241	lipid digestion
	xrefs	Reactome:R-HSA-192456 "Digestion of dietary lipid"	WAS	N/A
biological_process	GO:0044245	polysaccharide digestion
	xrefs	Reactome:R-HSA-189085 "Digestion of dietary carbohydrate"	WAS	N/A
biological_process	GO:0044409	symbiont entry into host
	xrefs	Reactome:R-HSA-173107 "Binding and entry of HIV virion"	WAS	N/A
biological_process	GO:0044419	biological process involved in interspecies interaction between organisms
	xrefs	Reactome:R-HSA-9824443 "Parasitic Infection Pathways"	WAS	N/A
biological_process	GO:0044528	regulation of mitochondrial mRNA stability
	xrefs	Reactome:R-HSA-9837092 "FASTK family proteins regulate processing and stability of mitochondrial RNAs"	WAS	N/A
biological_process	GO:0044725	epigenetic programming in the zygotic pronuclei
	xrefs	Reactome:R-HSA-9821002 "Chromatin modifications during the maternal to zygotic transition (MZT)";Reactome:R-HSA-9821993 "Replacement of protamines by nucleosomes in the male pronucleus"	WAS	N/A
biological_process	GO:0045003	double-strand break repair via synthesis-dependent strand annealing
	xrefs	Reactome:R-HSA-5693554 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"	WAS	N/A
biological_process	GO:0045007	depurination
	xrefs	Reactome:R-HSA-73927 "Depurination";Wikipedia:Depurination	WAS	Wikipedia:Depurination
biological_process	GO:0045008	depyrimidination
	xrefs	Reactome:R-HSA-73928 "Depyrimidination"	WAS	N/A
biological_process	GO:0045046	protein import into peroxisome membrane
	xrefs	Reactome:R-HSA-9603798 "Class I peroxisomal membrane protein import"	WAS	N/A
biological_process	GO:0045048	protein insertion into ER membrane
	xrefs	Reactome:R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"	WAS	N/A
biological_process	GO:0045087	innate immune response
	xrefs	Reactome:R-HSA-168249 "Innate Immune System";Wikipedia:Innate_immune_system	WAS	Wikipedia:Innate_immune_system
biological_process	GO:0045216	cell-cell junction organization
	xrefs	Reactome:R-HSA-421270 "Cell-cell junction organization"	WAS	N/A
biological_process	GO:0045329	carnitine biosynthetic process
	xrefs	Reactome:R-HSA-71262 "Carnitine synthesis"	WAS	N/A
biological_process	GO:0045332	phospholipid translocation
	xrefs	Reactome:R-HSA-1660502 "PIPs transport between early and late endosome membranes";Reactome:R-HSA-1660508 "PIPs transport between late endosome and Golgi membranes";Reactome:R-HSA-1660510 "PIPs transport between Golgi and plasma membranes";Reactome:R-HSA-1660524 "PIPs transport between plasma and early endosome membranes";Reactome:R-HSA-1660537 "PIPs transport between early endosome and Golgi membranes"	WAS	N/A
biological_process	GO:0045454	cell redox homeostasis
	xrefs	Reactome:R-HSA-1222541 "Cell redox homeostasis";Reactome:R-HSA-1222556 "ROS and RNS production in phagocytes";Wikipedia:Redox	WAS	Wikipedia:Redox
biological_process	GO:0045540	regulation of cholesterol biosynthetic process
	xrefs	Reactome:R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)"	WAS	N/A
biological_process	GO:0045589	regulation of regulatory T cell differentiation
	xrefs	Reactome:R-HSA-8877330 "RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)"	WAS	N/A
biological_process	GO:0045616	regulation of keratinocyte differentiation
	xrefs	Reactome:R-HSA-8939242 "RUNX1 regulates transcription of genes involved in differentiation of keratinocytes"	WAS	N/A
biological_process	GO:0045637	regulation of myeloid cell differentiation
	xrefs	Reactome:R-HSA-8939246 "RUNX1 regulates transcription of genes involved in differentiation of myeloid cells"	WAS	N/A
biological_process	GO:0045652	regulation of megakaryocyte differentiation
	xrefs	Reactome:R-HSA-8936459 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"	WAS	N/A
biological_process	GO:0045740	positive regulation of DNA replication
	xrefs	Reactome:R-HSA-69656 "Cyclin A:Cdk2-associated events at S phase entry"	WAS	N/A
biological_process	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
	xrefs	Reactome:R-HSA-8849469 "PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"	WAS	N/A
biological_process	GO:0045746	negative regulation of Notch signaling pathway
	xrefs	Reactome:R-HSA-9604323 "Negative regulation of NOTCH4 signaling"	WAS	N/A
biological_process	GO:0045786	negative regulation of cell cycle
	xrefs	Reactome:R-HSA-193670 "p75NTR negatively regulates cell cycle via SC1"	WAS	N/A
biological_process	GO:0045787	positive regulation of cell cycle
	xrefs	Reactome:R-HSA-8849470 "PTK6 Regulates Cell Cycle"	WAS	N/A
biological_process	GO:0045814	negative regulation of gene expression, epigenetic
	xrefs	Reactome:R-HSA-212300 "PRC2 methylates histones and DNA";Reactome:R-HSA-5250941 "Negative epigenetic regulation of rRNA expression"	WAS	N/A
biological_process	GO:0045815	transcription initiation-coupled chromatin remodeling
	xrefs	Reactome:R-HSA-5250913 "Positive epigenetic regulation of rRNA expression"	WAS	N/A
biological_process	GO:0045930	negative regulation of mitotic cell cycle
	xrefs	Reactome:R-HSA-8854050 "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"	WAS	N/A
biological_process	GO:0045944	positive regulation of transcription by RNA polymerase II
	xrefs	Reactome:R-HSA-2173796 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";Reactome:R-HSA-8866906 "TFAP2 (AP-2) family regulates transcription of other transcription factors";Reactome:R-HSA-8866907 "Activation of the TFAP2 (AP-2) family of transcription factors"	WAS	N/A
biological_process	GO:0046134	pyrimidine nucleoside biosynthetic process
	xrefs	Reactome:R-HSA-500753 "Pyrimidine biosynthesis"	WAS	N/A
biological_process	GO:0046135	pyrimidine nucleoside catabolic process
	xrefs	Reactome:R-HSA-73621 "Pyrimidine catabolism"	WAS	N/A
biological_process	GO:0046146	tetrahydrobiopterin metabolic process
	xrefs	Reactome:R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"	WAS	N/A
biological_process	GO:0046209	nitric oxide metabolic process
	xrefs	Reactome:R-HSA-202131 "Metabolism of nitric oxide	WAS	N/A
biological_process	GO:0046219	indolalkylamine biosynthetic process
	xrefs	Reactome:R-HSA-209931 "Serotonin and melatonin biosynthesis"	WAS	N/A
biological_process	GO:0046222	aflatoxin metabolic process
	xrefs	Reactome:R-HSA-5423646 "Aflatoxin activation and detoxification"	WAS	N/A
biological_process	GO:0046300	2,4-dichlorophenoxyacetic acid catabolic process
	xrefs	UM-BBD_pathwayID:2\,4-d	WAS	N/A
biological_process	GO:0046370	fructose biosynthetic process
	xrefs	Reactome:R-HSA-5652227 "Fructose biosynthesis"	WAS	N/A
biological_process	GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT
	xrefs	Reactome:R-HSA-8849474 "PTK6 Activates STAT3"	WAS	N/A
biological_process	GO:0046457	prostanoid biosynthetic process
	xrefs	Reactome:R-HSA-2162123 "Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";Wikipedia:Prostanoid#Biosynthesis	WAS	Wikipedia:Prostanoid#Biosynthesis
biological_process	GO:0046474	glycerophospholipid biosynthetic process
	xrefs	Reactome:R-HSA-1483206 "Glycerophospholipid biosynthesis"	WAS	N/A
biological_process	GO:0046475	glycerophospholipid catabolic process
	xrefs	Reactome:R-HSA-6814848 "Glycerophospholipid catabolism"	WAS	N/A
biological_process	GO:0046479	glycosphingolipid catabolic process
	xrefs	Reactome:R-HSA-9840310 "Glycosphingolipid catabolism"	WAS	N/A
biological_process	GO:0046579	positive regulation of Ras protein signal transduction
	xrefs	Reactome:R-HSA-9026519 "Activated NTRK2 signals through RAS";Reactome:R-HSA-9027284 "Erythropoietin activates RAS";Reactome:R-HSA-9034864 "Activated NTRK3 signals through RAS"	WAS	N/A
biological_process	GO:0046655	folic acid metabolic process
	xrefs	Reactome:R-HSA-196757 "Metabolism of folate and pterines"	WAS	N/A
biological_process	GO:0046676	negative regulation of insulin secretion
	xrefs	Reactome:R-HSA-400042 "Adrenaline,noradrenaline inhibits insulin secretion"	WAS	N/A
biological_process	GO:0046677	response to antibiotic
	xrefs	Reactome:R-HSA-9639775 "Antimicrobial action and antimicrobial resistance in Mtb"	WAS	N/A
biological_process	GO:0046718	symbiont entry into host cell
	xrefs	Reactome:R-HSA-168270 "Fusion and Uncoating of the Influenza Virion";Reactome:R-HSA-8876384 "Listeria monocytogenes entry into host cells";VZ:936 "Virus entry"	WAS	VZ:936 "Virus entry"
biological_process	GO:0046949	fatty-acyl-CoA biosynthetic process
	xrefs	Reactome:R-HSA-75105 "Fatty acyl-CoA biosynthesis"	WAS	N/A
biological_process	GO:0046951	ketone body biosynthetic process
	xrefs	Reactome:R-HSA-77111 "Synthesis of Ketone Bodies"	WAS	N/A
biological_process	GO:0046952	ketone body catabolic process
	xrefs	MetaCyc:PWY66-368;Reactome:R-HSA-77108 "Utilization of Ketone Bodies"	WAS	MetaCyc:PWY66-368
biological_process	GO:0048009	insulin-like growth factor receptor signaling pathway
	xrefs	Reactome:R-HSA-2404192 "Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"	WAS	N/A
biological_process	GO:0048010	vascular endothelial growth factor receptor signaling pathway
	xrefs	Reactome:R-HSA-194138 "Signaling by VEGF"	WAS	N/A
biological_process	GO:0048011	neurotrophin TRK receptor signaling pathway
	xrefs	Reactome:R-HSA-166520 "Signaling by NTRKs";Reactome:R-HSA-167021 "PLC-gamma1 signalling";Reactome:R-HSA-187042 "TRKA activation by NGF";Reactome:R-HSA-193704 "p75 NTR receptor-mediated signalling"	WAS	N/A
biological_process	GO:0048012	hepatocyte growth factor receptor signaling pathway
	xrefs	Reactome:R-HSA-8852405 "Signaling by MST1"	WAS	N/A
biological_process	GO:0048013	ephrin receptor signaling pathway
	xrefs	Reactome:R-HSA-2682334 "EPH-Ephrin signaling"	WAS	N/A
biological_process	GO:0048208	COPII vesicle coating
	xrefs	Reactome:R-HSA-204005 "COPII-mediated vesicle transport"	WAS	N/A
biological_process	GO:0048239	negative regulation of DNA recombination at telomere
	xrefs	Reactome:R-HSA-9670095 "Inhibition of DNA recombination at telomere"	WAS	N/A
biological_process	GO:0048313	Golgi inheritance
	xrefs	Reactome:R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization"	WAS	N/A
biological_process	GO:0048320	axial mesoderm formation
	xrefs	Reactome:R-HSA-9796292 "Formation of axial mesoderm"	WAS	N/A
biological_process	GO:0048341	paraxial mesoderm formation
	xrefs	Reactome:R-HSA-9793380 "Formation of paraxial mesoderm"	WAS	N/A
biological_process	GO:0048370	lateral mesoderm formation
	xrefs	Reactome:R-HSA-9758920 "Formation of lateral plate mesoderm"	WAS	N/A
biological_process	GO:0048391	intermediate mesoderm formation
	xrefs	Reactome:R-HSA-9761174 "Formation of intermediate mesoderm"	WAS	N/A
biological_process	GO:0048609	multicellular organismal reproductive process
	xrefs	Reactome:R-HSA-1474165 "Reproduction"	WAS	N/A
biological_process	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
	xrefs	Reactome:R-HSA-156584 "Cytosolic sulfonation of small molecules"	WAS	MetaCyc:PWY-5340
biological_process	GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process
	xrefs	MetaCyc:PWY-5340	WAS	N/A
biological_process	GO:0050434	positive regulation of viral transcription
	xrefs	Reactome:R-HSA-167246 "Tat-mediated elongation of the HIV-1 transcript"	WAS	N/A
biological_process	GO:0050728	negative regulation of inflammatory response
	xrefs	Reactome:R-HSA-9018678 "Biosynthesis of specialized proresolving mediators (SPMs)"	WAS	N/A
biological_process	GO:0050770	regulation of axonogenesis
	xrefs	Reactome:R-HSA-193697 "p75NTR regulates axonogenesis"	WAS	N/A
biological_process	GO:0050771	negative regulation of axonogenesis
	xrefs	Reactome:R-HSA-193634 "Axonal growth inhibition (RHOA activation)"	WAS	N/A
biological_process	GO:0050772	positive regulation of axonogenesis
	xrefs	Reactome:R-HSA-209563 "Axonal growth stimulation"	WAS	N/A
biological_process	GO:0050776	regulation of immune response
	xrefs	Reactome:R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"	WAS	N/A
biological_process	GO:0050796	regulation of insulin secretion
	xrefs	Reactome:R-HSA-422356 "Regulation of insulin secretion"	WAS	N/A
biological_process	GO:0050852	T cell receptor signaling pathway
	xrefs	Reactome:R-HSA-202403 "TCR signaling"	WAS	N/A
biological_process	GO:0050855	regulation of B cell receptor signaling pathway
	xrefs	Reactome:R-HSA-8939245 "RUNX1 regulates transcription of genes involved in BCR signaling"	WAS	N/A
biological_process	GO:0050872	white fat cell differentiation
	xrefs	Reactome:R-HSA-381340 "Transcriptional regulation of white adipocyte differentiation"	WAS	N/A
biological_process	GO:0050892	intestinal absorption
	xrefs	Reactome:R-HSA-8963676 "Intestinal absorption"	WAS	N/A
biological_process	GO:0050900	leukocyte migration
	xrefs	Reactome:R-HSA-202733 "Cell surface interactions at the vascular wall"	WAS	N/A
biological_process	GO:0050909	sensory perception of taste
	xrefs	Reactome:R-HSA-9717189 "Sensory perception of taste";Wikipedia:Taste	WAS	Wikipedia:Taste
biological_process	GO:0051056	regulation of small GTPase mediated signal transduction
	xrefs	Reactome:R-HSA-9012999 "RHO GTPase cycle"	WAS	N/A
biological_process	GO:0051084	'de novo' post-translational protein folding
	xrefs	Reactome:R-HSA-391251 "Protein folding"	WAS	N/A
biological_process	GO:0051086	chaperone mediated protein folding independent of cofactor
	xrefs	Reactome:R-HSA-390450 "Folding of actin by CCT/TriC"	WAS	N/A
biological_process	GO:0051090	regulation of DNA-binding transcription factor activity
	xrefs	Reactome:R-HSA-9708530 "Regulation of BACH1 activity"	WAS	N/A
biological_process	GO:0051121	hepoxilin metabolic process
	xrefs	Reactome:R-HSA-2142696 "Synthesis of Hepoxilins (HX) and Trioxilins (TrX)"	WAS	N/A
biological_process	GO:0051149	positive regulation of muscle cell differentiation
	xrefs	Reactome:R-HSA-525793 "Myogenesis"	WAS	N/A
biological_process	GO:0051306	mitotic sister chromatid separation
	xrefs	Reactome:R-HSA-2467813 "Separation of Sister Chromatids"	WAS	N/A
biological_process	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway
	xrefs	Reactome:R-HSA-9024909 "BDNF activates NTRK2 (TRKB) signaling";Reactome:R-HSA-9025046 "NTF3 activates NTRK2 (TRKB) signaling";Reactome:R-HSA-9026357 "NTF4 activates NTRK2 (TRKB) signaling";Reactome:R-HSA-9034013 "NTF3 activates NTRK3 signaling";Reactome:R-HSA-9034793 "Activated NTRK3 signals through PLCG1"	WAS	N/A
biological_process	GO:0051403	stress-activated MAPK cascade
	xrefs	Reactome:R-HSA-450294 "MAP kinase activation"	WAS	N/A
biological_process	GO:0051607	defense response to virus
	xrefs	Reactome:R-HSA-8983711 "OAS antiviral response"	WAS	N/A
biological_process	GO:0051701	biological process involved in interaction with host
	xrefs	Reactome:R-HSA-9635486 "Infection with Mycobacterium tuberculosis";Reactome:R-HSA-9658195 "Leishmania infection"	WAS	N/A
biological_process	GO:0051711	negative regulation of killing of cells of another organism
	xrefs	Reactome:R-HSA-9662851 "Anti-inflammatory response favouring Leishmania parasite infection"	WAS	N/A
biological_process	GO:0051716	cellular response to stimulus
	xrefs	Reactome:R-HSA-8953897 "Cellular responses to stimuli"	WAS	N/A
biological_process	GO:0051726	regulation of cell cycle
	xrefs	Reactome:R-HSA-156711 "Polo-like kinase mediated events";Reactome:R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK"	WAS	N/A
biological_process	GO:0051896	regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
	xrefs	Reactome:R-HSA-6811558 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"	WAS	N/A
biological_process	GO:0051897	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
	xrefs	Reactome:R-HSA-1257604 "PIP3 activates AKT signaling";Reactome:R-HSA-165158 "Activation of AKT2";Reactome:R-HSA-9027276 "Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";Reactome:R-HSA-9028335 "Activated NTRK2 signals through PI3K";Reactome:R-HSA-9603381 "Activated NTRK3 signals through PI3K"	WAS	N/A
biological_process	GO:0051899	membrane depolarization
	xrefs	Reactome:R-HSA-112308 "Presynaptic depolarization and calcium channel opening"	WAS	N/A
biological_process	GO:0051936	gamma-aminobutyric acid reuptake
	xrefs	Reactome:R-HSA-888593 "Reuptake of GABA"	WAS	N/A
biological_process	GO:0052031	symbiont-mediated perturbation of host defense response
	xrefs	Reactome:R-HSA-9637628 "Modulation by Mtb of host immune system";Reactome:R-HSA-9637690 "Response of Mtb to phagocytosis"	WAS	N/A
biological_process	GO:0052150	symbiont-mediated perturbation of host apoptosis
	xrefs	VZ:1518 "Apoptosis modulation"	WAS	VZ:1518 "Apoptosis modulation";VZ:1581 "Apoptosis modulation"
biological_process	GO:0052164	symbiont defense to host-produced reactive oxygen species
	xrefs	Reactome:R-HSA-1222387 "Tolerance of reactive oxygen produced by macrophages"	WAS	N/A
biological_process	GO:0052165	symbiont-mediated perturbation of host phytoalexin production
	xrefs	PMID:28805743	WAS	N/A
biological_process	GO:0052170	symbiont-mediated suppression of host innate immune response
	xrefs	Reactome:R-HSA-9637687 "Suppression of phagosomal maturation"	WAS	N/A
biological_process	GO:0052572	response to host immune response
	xrefs	Reactome:R-HSA-1222499 "Latent infection - Other responses of Mtb to phagocytosis"	WAS	N/A
biological_process	GO:0052776	chitin catabolic process to fructose 6-phosphate via glucosamine
	xrefs	MetaCyc:PWY-6855	WAS	N/A
biological_process	GO:0055085	transmembrane transport
	xrefs	Reactome:R-HSA-382556 "ABC-family proteins mediated transport";Reactome:R-HSA-425407 "SLC-mediated transmembrane transport";Reactome:R-HSA-5223345 "Miscellaneous transport and binding events"	WAS	N/A
biological_process	GO:0055086	nucleobase-containing small molecule metabolic process
	xrefs	Reactome:R-HSA-15869 "Metabolism of nucleotides";Reactome:R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins"	WAS	N/A
biological_process	GO:0060070	canonical Wnt signaling pathway
	xrefs	Reactome:R-HSA-4641262 "Disassembly of the destruction complex and recruitment of AXIN to the membrane"	WAS	N/A
biological_process	GO:0060071	Wnt signaling pathway, planar cell polarity pathway
	xrefs	Reactome:R-HSA-4086400 "PCP/CE pathway"	WAS	N/A
biological_process	GO:0060236	regulation of mitotic spindle organization
	xrefs	Reactome:R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes"	WAS	N/A
biological_process	GO:0060260	regulation of transcription initiation by RNA polymerase II
	xrefs	Reactome:R-HSA-212436 "Generic Transcription Pathway"	WAS	N/A
biological_process	GO:0060271	cilium assembly
	xrefs	Reactome:R-HSA-5617833 "Cilium Assembly"	WAS	N/A
biological_process	GO:0060326	cell chemotaxis
	xrefs	Reactome:R-HSA-9664424 "Cell recruitment (pro-inflammatory response)"	WAS	N/A
biological_process	GO:0060333	type II interferon-mediated signaling pathway
	xrefs	Reactome:R-HSA-877300 "Interferon gamma signaling"	WAS	N/A
biological_process	GO:0060334	regulation of type II interferon-mediated signaling pathway
	xrefs	Reactome:R-HSA-877312 "Regulation of IFNG signaling"	WAS	N/A
biological_process	GO:0060337	type I interferon-mediated signaling pathway
	xrefs	Reactome:R-HSA-909733 "Interferon alpha/beta signaling"	WAS	N/A
biological_process	GO:0060338	regulation of type I interferon-mediated signaling pathway
	xrefs	Reactome:R-HSA-912694 "Regulation of IFNA/IFNB signaling"	WAS	N/A
biological_process	GO:0060397	growth hormone receptor signaling pathway via JAK-STAT
	xrefs	Reactome:R-HSA-982772 "Growth hormone receptor signaling"	WAS	N/A
biological_process	GO:0060544	regulation of necroptotic process
	xrefs	Reactome:R-HSA-5675482 "Regulation of necroptotic cell death"	WAS	N/A
biological_process	GO:0060676	ureteric bud formation
	xrefs	Reactome:R-HSA-9830674 "Formation of the ureteric bud"	WAS	N/A
biological_process	GO:0060765	regulation of androgen receptor signaling pathway
	xrefs	Reactome:R-HSA-5625886 "Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"	WAS	N/A
biological_process	GO:0060896	neural plate pattern specification
	xrefs	Reactome:R-HSA-9834899 "Specification of the neural plate border"	WAS	N/A
biological_process	GO:0060914	heart formation
	xrefs	Reactome:R-HSA-9733709 "Cardiogenesis"	WAS	N/A
biological_process	GO:0060964	regulation of miRNA-mediated gene silencing
	xrefs	Reactome:R-HSA-5578749 "Transcriptional regulation by small RNAs"	WAS	N/A
biological_process	GO:0061024	membrane organization
	xrefs	Reactome:R-HSA-199991 "Membrane Trafficking"	WAS	N/A
biological_process	GO:0061337	cardiac conduction
	xrefs	Reactome:R-HSA-5576891 "Cardiac conduction"	WAS	N/A
biological_process	GO:0061621	canonical glycolysis
	xrefs	MetaCyc:ANAGLYCOLYSIS-PWY;Reactome:R-HSA-70171 "Glycolysis";Wikipedia:Glycolysis	WAS	MetaCyc:ANAGLYCOLYSIS-PWY;Wikipedia:Glycolysis
biological_process	GO:0061624	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
	xrefs	Reactome:R-HSA-70350 "Fructose catabolism"	WAS	N/A
biological_process	GO:0061684	chaperone-mediated autophagy
	xrefs	Reactome:R-HSA-9613829 "Chaperone Mediated Autophagy";Wikipedia:Chaperone-mediated_autophagy	WAS	Wikipedia:Chaperone-mediated_autophagy
biological_process	GO:0061724	lipophagy
	xrefs	Reactome:R-HSA-9613354 "Lipophagy"	WAS	N/A
biological_process	GO:0061729	GDP-D-mannose biosynthetic process from fructose-6-phosphate
	xrefs	MetaCyc:PWY-5659	WAS	N/A
biological_process	GO:0061738	late endosomal microautophagy
	xrefs	Reactome:R-HSA-9615710 "Late endosomal microautophagy"	WAS	N/A
biological_process	GO:0062012	regulation of small molecule metabolic process
	xrefs	Reactome:R-HSA-9861718 "Regulation of pyruvate metabolism"	WAS	N/A
biological_process	GO:0062197	cellular response to chemical stress
	xrefs	Reactome:R-HSA-9711123 "Cellular response to chemical stress"	WAS	N/A
biological_process	GO:0070102	interleukin-6-mediated signaling pathway
	xrefs	Reactome:R-HSA-1059683 "Interleukin-6 signaling"	WAS	N/A
biological_process	GO:0070106	interleukin-27-mediated signaling pathway
	xrefs	Reactome:R-HSA-9020956 "Interleukin-27 signaling"	WAS	N/A
biological_process	GO:0070124	mitochondrial translational initiation
	xrefs	Reactome:R-HSA-5368286 "Mitochondrial translation initiation"	WAS	N/A
biological_process	GO:0070125	mitochondrial translational elongation
	xrefs	Reactome:R-HSA-5389840 "Mitochondrial translation elongation"	WAS	N/A
biological_process	GO:0070126	mitochondrial translational termination
	xrefs	Reactome:R-HSA-5419276 "Mitochondrial translation termination"	WAS	N/A
biological_process	GO:0070221	sulfide oxidation, using sulfide:quinone oxidoreductase
	xrefs	MetaCyc:P222-PWY;Reactome:R-HSA-1614517 "Sulfide oxidation to sulfate"	WAS	MetaCyc:P222-PWY
biological_process	GO:0070266	necroptotic process
	xrefs	Reactome:R-HSA-5213460 "RIPK1-mediated regulated necrosis"	WAS	N/A
biological_process	GO:0070268	cornification
	xrefs	Reactome:R-HSA-6809371 "Formation of the cornified envelope"	WAS	N/A
biological_process	GO:0070269	pyroptotic inflammatory response
	xrefs	Reactome:R-HSA-5620971 "Pyroptosis"	WAS	N/A
biological_process	GO:0070317	negative regulation of G0 to G1 transition
	xrefs	Reactome:R-HSA-8953750 "Transcriptional Regulation by E2F6"	WAS	N/A
biological_process	GO:0070371	ERK1 and ERK2 cascade
	xrefs	Reactome:R-HSA-112409 "RAF-independent MAPK1/3 activation"	WAS	N/A
biological_process	GO:0070498	interleukin-1-mediated signaling pathway
	xrefs	Reactome:R-HSA-9020702 "Interleukin-1 signaling"	WAS	N/A
biological_process	GO:0070588	calcium ion transmembrane transport
	xrefs	Reactome:R-HSA-3295583 "TRP channels"	WAS	N/A
biological_process	GO:0070757	interleukin-35-mediated signaling pathway
	xrefs	Reactome:R-HSA-8984722 "Interleukin-35 Signalling"	WAS	N/A
biological_process	GO:0070830	bicellular tight junction assembly
	xrefs	Reactome:R-HSA-420029 "Tight junction interactions"	WAS	N/A
biological_process	GO:0070900	mitochondrial tRNA modification
	xrefs	Reactome:R-HSA-6787450 "tRNA modification in the mitochondrion"	WAS	N/A
biological_process	GO:0070911	global genome nucleotide-excision repair
	xrefs	Reactome:R-HSA-5696399 "Global Genome Nucleotide Excision Repair (GG-NER)"	WAS	N/A
biological_process	GO:0070987	error-free translesion synthesis
	xrefs	Reactome:R-HSA-110320 "Translesion Synthesis by POLH"	WAS	N/A
biological_process	GO:0071260	cellular response to mechanical stimulus
	xrefs	Reactome:R-HSA-9855142 "Cellular responses to mechanical stimuli"	WAS	N/A
biological_process	GO:0071344	diphosphate metabolic process
	xrefs	Reactome:R-HSA-71737 "Pyrophosphate hydrolysis"	WAS	N/A
biological_process	GO:0071345	cellular response to cytokine stimulus
	xrefs	Reactome:R-HSA-9007892 "Interleukin-38 signaling";Reactome:R-HSA-9008059 "Interleukin-37 signaling"	WAS	N/A
biological_process	GO:0071377	cellular response to glucagon stimulus
	xrefs	Reactome:R-HSA-163359 "Glucagon signaling in metabolic regulation"	WAS	N/A
biological_process	GO:0071383	cellular response to steroid hormone stimulus
	xrefs	Reactome:R-HSA-3371497 "HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand"	WAS	N/A
biological_process	GO:0071456	cellular response to hypoxia
	xrefs	Reactome:R-HSA-1234174 "Cellular response to hypoxia"	WAS	N/A
biological_process	GO:0071495	cellular response to endogenous stimulus
	xrefs	Reactome:R-HSA-9860931 "Response of endothelial cells to shear stress"	WAS	N/A
biological_process	GO:0071514	genomic imprinting
	xrefs	N/A	WAS	Wikipedia:Genomic_imprinting
biological_process	GO:0071550	death-inducing signaling complex assembly
	xrefs	Reactome:R-HSA-5357786 "TNFR1-induced proapoptotic signaling"	WAS	N/A
biological_process	GO:0071577	zinc ion transmembrane transport
	xrefs	Reactome:R-HSA-435354 "Zinc transporters"	WAS	N/A
biological_process	GO:0071805	potassium ion transmembrane transport
	xrefs	Reactome:R-HSA-1296071 "Potassium Channels"	WAS	N/A
biological_process	GO:0071827	plasma lipoprotein particle organization
	xrefs	Reactome:R-HSA-174824 "Plasma lipoprotein assembly, remodeling, and clearance"	WAS	N/A
biological_process	GO:0072179	nephric duct formation
	xrefs	Reactome:R-HSA-9830364 "Formation of the nephric duct"	WAS	N/A
biological_process	GO:0072210	metanephric nephron development
	xrefs	Reactome:R-HSA-9831926 "Nephron development"	WAS	N/A
biological_process	GO:0072530	purine-containing compound transmembrane transport
	xrefs	Reactome:R-HSA-2161517 "Abacavir transmembrane transport"	WAS	N/A
biological_process	GO:0075001	adhesion of symbiont infection structure to host
	xrefs	Reactome:R-HSA-9664407 "Parasite infection"	WAS	N/A
biological_process	GO:0075713	establishment of integrated proviral latency
	xrefs	Reactome:R-HSA-162592 "Integration of provirus";VZ:980 "Viral genome integration"	WAS	VZ:980 "Viral genome integration"
biological_process	GO:0075733	intracellular transport of virus
	xrefs	Reactome:R-HSA-168271 "Transport of Ribonucleoproteins into the Host Nucleus";Reactome:R-HSA-168274 "Export of Viral Ribonucleoproteins from Nucleus";Reactome:R-HSA-174490 "Membrane binding and targetting of GAG proteins"	WAS	N/A
biological_process	GO:0090009	primitive streak formation
	xrefs	Reactome:R-HSA-9754189 "Germ layer formation at gastrulation"	WAS	N/A
biological_process	GO:0090017	anterior neural plate formation
	xrefs	Reactome:R-HSA-9823739 "Formation of the anterior neural plate"	WAS	N/A
biological_process	GO:0090018	posterior neural plate formation
	xrefs	Reactome:R-HSA-9832991 "Formation of the posterior neural plate"	WAS	N/A
biological_process	GO:0090090	negative regulation of canonical Wnt signaling pathway
	xrefs	Reactome:R-HSA-3772470 "Negative regulation of TCF-dependent signaling by WNT ligand antagonists";Reactome:R-HSA-4641258 "Degradation of DVL"	WAS	N/A
biological_process	GO:0090263	positive regulation of canonical Wnt signaling pathway
	xrefs	Reactome:R-HSA-4641257 "Degradation of AXIN"	WAS	N/A
biological_process	GO:0090335	regulation of brown fat cell differentiation
	xrefs	Reactome:R-HSA-9843743 "Transcriptional regulation of brown and beige adipocyte differentiation"	WAS	N/A
biological_process	GO:0090398	cellular senescence
	xrefs	Reactome:R-HSA-2559583 "Cellular Senescence"	WAS	N/A
biological_process	GO:0090638	phosphatidylcholine biosynthesis from phosphatidylethanolamine
	xrefs	MetaCyc:PWY-6825	WAS	N/A
biological_process	GO:0090640	phosphatidylcholine biosynthesis from sn-glycero-3-phosphocholine
	xrefs	MetaCyc:PWY-7470	WAS	N/A
biological_process	GO:0090646	mitochondrial tRNA processing
	xrefs	Reactome:R-HSA-6785470 "tRNA processing in the mitochondrion"	WAS	N/A
biological_process	GO:0097055	agmatine biosynthetic process
	xrefs	Reactome:R-HSA-351143 "Agmatine biosynthesis"	WAS	N/A
biological_process	GO:0097190	apoptotic signaling pathway
	xrefs	Reactome:R-HSA-193681 "Ceramide signalling";Reactome:R-HSA-204998 "Cell death signalling via NRAGE, NRIF and NADE";Reactome:R-HSA-75157 "FasL/ CD95L signaling"	WAS	N/A
biological_process	GO:0097191	extrinsic apoptotic signaling pathway
	xrefs	Reactome:R-HSA-5357769 "Caspase activation via extrinsic apoptotic signalling pathway"	WAS	N/A
biological_process	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand
	xrefs	Reactome:R-HSA-418889 "Caspase activation via Dependence Receptors in the absence of ligand"	WAS	N/A
biological_process	GO:0097193	intrinsic apoptotic signaling pathway
	xrefs	Reactome:R-HSA-109606 "Intrinsic Pathway for Apoptosis"	WAS	N/A
biological_process	GO:0097194	execution phase of apoptosis
	xrefs	Reactome:R-HSA-75153 "Apoptotic execution phase"	WAS	N/A
biological_process	GO:0097267	omega-hydroxylase P450 pathway
	xrefs	Reactome:R-HSA-2142816 "Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)"	WAS	N/A
biological_process	GO:0097300	programmed necrotic cell death
	xrefs	Reactome:R-HSA-5218859 "Regulated Necrosis"	WAS	N/A
biological_process	GO:0097400	interleukin-17-mediated signaling pathway
	xrefs	Reactome:R-HSA-448424 "Interleukin-17 signaling"	WAS	N/A
biological_process	GO:0097700	vascular endothelial cell response to laminar fluid shear stress
	xrefs	Reactome:R-HSA-9856530 "High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells"	WAS	N/A
biological_process	GO:0097706	vascular endothelial cell response to oscillatory fluid shear stress
	xrefs	Reactome:R-HSA-9860927 "Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells"	WAS	N/A
biological_process	GO:0097711	ciliary basal body-plasma membrane docking
	xrefs	Reactome:R-HSA-5620912 "Anchoring of the basal body to the plasma membrane"	WAS	N/A
biological_process	GO:0098780	response to mitochondrial depolarisation
	xrefs	Reactome:R-HSA-9840373 "Cellular response to mitochondrial stress"	WAS	N/A
biological_process	GO:0098856	intestinal lipid absorption
	xrefs	Reactome:R-HSA-8963678 "Intestinal lipid absorption"	WAS	N/A
biological_process	GO:0106001	intestinal hexose absorption
	xrefs	Reactome:R-HSA-8981373 "Intestinal hexose absorption"	WAS	N/A
biological_process	GO:0120116	glucagon processing
	xrefs	Reactome:R-HSA-381771 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"	WAS	N/A
biological_process	GO:0141005	transposable element silencing by heterochromatin formation
	xrefs	Reactome:R-HSA-9842860 "Regulation of endogenous retroelements"	WAS	N/A
biological_process	GO:0141006	transposable element silencing by piRNA-mediated heterochromatin formation
	xrefs	Reactome:R-HSA-9845323 "Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)"	WAS	N/A
biological_process	GO:0141082	symbiont-mediated detoxification of host-generated reactive oxygen species
	xrefs	Reactome:R-HSA-1222538 "Tolerance by Mtb to nitric oxide produced by macrophages"	WAS	N/A
biological_process	GO:0141167	chromosomal 5-methylcytosine DNA demethylation, oxidation pathway
	xrefs	Reactome:R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA"	WAS	N/A
biological_process	GO:0160021	maternal-to-zygotic transition of gene expression
	xrefs	Reactome:R-HSA-9816359 "Maternal to zygotic transition (MZT)"	WAS	N/A
biological_process	GO:1900034	regulation of cellular response to heat
	xrefs	Reactome:R-HSA-3371453 "Regulation of HSF1-mediated heat shock response";Reactome:R-HSA-3371571 "HSF1-dependent transactivation"	WAS	N/A
biological_process	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
	xrefs	Reactome:R-HSA-111452 "Activation and oligomerization of BAK protein";Reactome:R-HSA-114294 "Activation, translocation and oligomerization of BAX"	WAS	N/A
biological_process	GO:1901158	neomycin biosynthetic process
	xrefs	MetaCyc:PWY-7016	WAS	N/A
biological_process	GO:1901290	succinyl-CoA biosynthetic process
	xrefs	Reactome:R-HSA-9853506 "OGDH complex synthesizes succinyl-CoA from 2-OG"	WAS	N/A
biological_process	GO:1901381	positive regulation of potassium ion transmembrane transport
	xrefs	Reactome:R-HSA-1296041 "Activation of G protein gated Potassium channels";Reactome:R-HSA-1296052 "Ca2+ activated K+ channels"	WAS	N/A
biological_process	GO:1901687	glutathione derivative biosynthetic process
	xrefs	Reactome:R-HSA-156590 "Glutathione conjugation"	WAS	N/A
biological_process	GO:1901774	lincomycin biosynthetic process
	xrefs	MetaCyc:PWY-6955	WAS	N/A
biological_process	GO:1901780	pentalenolactone biosynthetic process
	xrefs	MetaCyc:PWY-6915	WAS	N/A
biological_process	GO:1901782	p-cumate catabolic process
	xrefs	MetaCyc:PWY-5273	WAS	N/A
biological_process	GO:1901796	regulation of signal transduction by p53 class mediator
	xrefs	Reactome:R-HSA-5633007 "Regulation of TP53 Activity"	WAS	N/A
biological_process	GO:1901802	1,5-anhydro-D-fructose catabolic process
	xrefs	MetaCyc:PWY-6992	WAS	N/A
biological_process	GO:1901812	beta-carotene biosynthetic process
	xrefs	MetaCyc:PWY-5943	WAS	N/A
biological_process	GO:1901815	astaxanthin biosynthetic process
	xrefs	MetaCyc:PWY-5288	WAS	N/A
biological_process	GO:1901824	alpha-carotene biosynthetic process
	xrefs	MetaCyc:PWY-5946	WAS	N/A
biological_process	GO:1901827	zeaxanthin biosynthetic process
	xrefs	MetaCyc:PWY-5944	WAS	N/A
biological_process	GO:1901830	zeaxanthin bis(beta-D-glucoside) biosynthetic process
	xrefs	MetaCyc:PWY-6288	WAS	N/A
biological_process	GO:1901833	neoxanthin biosynthetic process
	xrefs	MetaCyc:PWY-6809	WAS	N/A
biological_process	GO:1901990	regulation of mitotic cell cycle phase transition
	xrefs	Reactome:R-HSA-174113 "SCF-beta-TrCP mediated degradation of Emi1";Reactome:R-HSA-176412 "Phosphorylation of the APC/C"	WAS	N/A
biological_process	GO:1902036	regulation of hematopoietic stem cell differentiation
	xrefs	Reactome:R-HSA-8939236 "RUNX1 regulates transcription of genes involved in differentiation of HSCs"	WAS	N/A
biological_process	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors
	xrefs	Reactome:R-HSA-3371378 "Regulation by c-FLIP"	WAS	N/A
biological_process	GO:1902600	proton transmembrane transport
	xrefs	Reactome:R-HSA-167826 "The fatty acid cycling model"	WAS	N/A
biological_process	GO:1902749	regulation of cell cycle G2/M phase transition
	xrefs	Reactome:R-HSA-8852276 "The role of GTSE1 in G2/M progression after G2 checkpoint"	WAS	N/A
biological_process	GO:1903604	cytochrome metabolic process
	xrefs	Reactome:R-HSA-211958 "Miscellaneous substrates"	WAS	N/A
biological_process	GO:1903749	positive regulation of establishment of protein localization to mitochondrion
	xrefs	Reactome:R-HSA-114452 "Activation of BH3-only proteins";Reactome:R-HSA-75108 "Activation, myristolyation of BID and translocation to mitochondria"	WAS	N/A
biological_process	GO:1903779	regulation of cardiac conduction
	xrefs	Reactome:R-HSA-5578768 "Physiological factors";Reactome:R-HSA-5578775 "Ion homeostasis"	WAS	N/A
biological_process	GO:1904177	regulation of adipose tissue development
	xrefs	Reactome:R-HSA-9843745 "Adipogenesis"	WAS	N/A
biological_process	GO:1904333	positive regulation of error-prone translesion synthesis
	xrefs	Reactome:R-HSA-110314 "Recognition of DNA damage by PCNA-containing replication complex"	WAS	N/A
biological_process	GO:1904380	endoplasmic reticulum mannose trimming
	xrefs	Reactome:R-HSA-901032 "ER Quality Control Compartment (ERQC)"	WAS	N/A
biological_process	GO:1904381	Golgi apparatus mannose trimming
	xrefs	Reactome:R-HSA-964827 "Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2"	WAS	N/A
biological_process	GO:1904538	regulation of glycolytic process through fructose-6-phosphate
	xrefs	Reactome:R-HSA-9634600 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"	WAS	N/A
biological_process	GO:1904837	beta-catenin-TCF complex assembly
	xrefs	Reactome:R-HSA-201722 "Formation of the beta-catenin:TCF transactivating complex"	WAS	N/A
biological_process	GO:1904894	positive regulation of receptor signaling pathway via STAT
	xrefs	Reactome:R-HSA-9027283 "Erythropoietin activates STAT5"	WAS	N/A
biological_process	GO:1905784	regulation of anaphase-promoting complex-dependent catabolic process
	xrefs	Reactome:R-HSA-176408 "Regulation of APC/C activators between G1/S and early anaphase"	WAS	N/A
biological_process	GO:1990000	amyloid fibril formation
	xrefs	Reactome:R-HSA-977225 "Amyloid fiber formation"	WAS	N/A
biological_process	GO:1990845	adaptive thermogenesis
	xrefs	Reactome:R-HSA-166187 "Mitochondrial Uncoupling"	WAS	N/A
biological_process	GO:2000047	regulation of cell-cell adhesion mediated by cadherin
	xrefs	Reactome:R-HSA-9764260 "Regulation of Expression and Function of Type II Classical Cadherins"	WAS	N/A
biological_process	GO:2000074	regulation of type B pancreatic cell development
	xrefs	Reactome:R-HSA-211163 "AKT-mediated inactivation of FOXO1A"	WAS	N/A
biological_process	GO:2000145	regulation of cell motility
	xrefs	Reactome:R-HSA-6785631 "ERBB2 Regulates Cell Motility"	WAS	N/A
biological_process	GO:2000304	positive regulation of ceramide biosynthetic process
	xrefs	Reactome:R-HSA-5626978 "TNFR1-mediated ceramide production"	WAS	N/A
biological_process	GO:2000310	regulation of NMDA receptor activity
	xrefs	Reactome:R-HSA-438066 "Unblocking of NMDA receptors, glutamate binding and activation"	WAS	N/A
biological_process	GO:2000810	regulation of bicellular tight junction assembly
	xrefs	Reactome:R-HSA-8935964 "RUNX1 regulates expression of components of tight junctions"	WAS	N/A
biological_process	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
	xrefs	Reactome:R-HSA-9603505 "NTRK3 as a dependence receptor"	WAS	N/A
biological_process	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
	xrefs	Reactome:R-HSA-111453 "BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members"	WAS	N/A
biological_process	GO:2001301	lipoxin biosynthetic process
	xrefs	Reactome:R-HSA-2142700 "Biosynthesis of Lipoxins (LX)"	WAS	N/A
biological_process	GO:2001312	lysobisphosphatidic acid biosynthetic process
	xrefs	Reactome:R-HSA-1483171 "Synthesis of BMP"	WAS	N/A
molecular_function	GO:0004077	biotin--[biotin carboxyl-carrier protein] ligase activity
	xrefs	EC:6.3.4.15;MetaCyc:BIOTINLIG-RXN;RHEA:11756	WAS	EC:6.3.4.15;MetaCyc:BIOTINLIG-RXN;Reactome:R-HSA-2993447 "HLCS biotinylates 6x(PCCA:PCCB)";Reactome:R-HSA-2993799 "HLCS biotinylates 6xMCCC1:6xMCCC2";Reactome:R-HSA-2993802 "HLCS biotinylates PC:Mn2+";Reactome:R-HSA-2993814 "HLCS biotinylates ACACA:Mn2+";Reactome:R-HSA-3323184 "Defective HLCS does not biotinylate ACACA:Mn2+";Reactome:R-HSA-4167511 "HLCS biotinylates ACACB";Reactome:R-HSA-9035987 "Defective HLCS does not biotinylate 6xMCCC1:6xMCCC2";Reactome:R-HSA-9035988 "Defective HLCS does not biotinylate PC:Mn2+";Reactome:R-HSA-9035990 "Defective HLCS does not biotinylate 6x(PCCA:PCCB)";RHEA:11756
molecular_function	GO:0004177	aminopeptidase activity
	xrefs	EC:3.4.11.-;https://www.ebi.ac.uk/merops/about/glossary.shtml#AMINOPEPTIDASE;MetaCyc:RXN0-5052;Reactome:R-HSA-1236954 "Trimming of peptides by IRAP in endocytic vesicles";Reactome:R-HSA-2534096 "METAP1/2 demethylates GNAT1";Reactome:R-HSA-983162 "Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases"	WAS	EC:3.4.11.-;MetaCyc:RXN0-5052;Reactome:R-HSA-1236954 "Trimming of peptides by IRAP in endocytic vesicles";Reactome:R-HSA-2534096 "METAP1/2 demethylates GNAT1";Reactome:R-HSA-983162 "Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases"
molecular_function	GO:0004197	cysteine-type endopeptidase activity
	xrefs	EC:3.4.22.-;Reactome:R-HSA-114252 "Cleavage of Procaspase-3 by the apoptosome";Reactome:R-HSA-114259 "Cleavage of Procaspase9 to caspase9";Reactome:R-HSA-114261 "Cleavage of Procaspase-7 by the apoptosome";Reactome:R-HSA-1236948 "Antigen processing by cathepsin S in endosoytic vesicle";Reactome:R-HSA-139898 "Caspase-8 activates BID by cleavage";Reactome:R-HSA-139952 "Caspase-8 processing in the DISC";Reactome:R-HSA-1678920 "TLR processing at low pH";Reactome:R-HSA-1678981 "TLR9 processing at neutral pH";Reactome:R-HSA-201595 "Caspase-mediated cleavage of plakophilin-1";Reactome:R-HSA-201603 "Caspase-mediated cleavage of PKC theta";Reactome:R-HSA-201608 "Caspase-mediated cleavage of alpha adducin";Reactome:R-HSA-201611 "Caspase-mediated cleavage of Rock-1";Reactome:R-HSA-201622 "Caspase-mediated cleavage of gelsolin";Reactome:R-HSA-201628 "Caspase-mediated cleavage of vimentin at DSVD (85)";Reactome:R-HSA-201629 "Caspase-mediated cleavage of Tau";Reactome:R-HSA-201630 "Caspase-mediated cleavage of Acinus";Reactome:R-HSA-201631 "Caspase-mediated cleavage of Desmoglein 3";Reactome:R-HSA-201634 "Caspase-mediated cleavage of FADK 1";Reactome:R-HSA-201636 "Caspase-mediated cleavage of Desmoplakin";Reactome:R-HSA-201637 "Caspase-mediated cleavage of plectin-1";Reactome:R-HSA-201639 "Caspase-mediated cleavage of GAS2";Reactome:R-HSA-201640 "Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha";Reactome:R-HSA-2028692 "Cleavage of p-STK4 (p-MST1) by caspase 3";Reactome:R-HSA-2028697 "Cleavage of p-STK3 (p-MST2) by caspase 3";Reactome:R-HSA-202917 "Caspase-mediated cleavage of Desmoglein 1";Reactome:R-HSA-202939 "Caspase-mediated cleavage of E-Cadherin";Reactome:R-HSA-202947 "Caspase mediated cleavage of APC";Reactome:R-HSA-202960 "Caspase mediated cleavage of C-IAP1";Reactome:R-HSA-202966 "Caspase mediated cleavage of HIP-55";Reactome:R-HSA-202967 "Caspase mediated cleavage of alpha-II-Fodrin";Reactome:R-HSA-202969 "Caspase mediated cleavage of beta-catenin";Reactome:R-HSA-211186 "Cleavage of DFF45 (224) by caspase-3";Reactome:R-HSA-211190 "Caspase 3-mediated cleavage of DFF45 (117)";Reactome:R-HSA-211651 "Cleavage of PAK-2 at 212";Reactome:R-HSA-212552 "Caspase 3-mediated cleavage of PKC delta";Reactome:R-HSA-2130336 "Initial proteolyis of Ii by aspartic proteases to lip22";Reactome:R-HSA-2130349 "Generation of CLIP from lip10";Reactome:R-HSA-2130504 "Cleavage of lip22 to lip10";Reactome:R-HSA-2130706 "MHC class II antigen processing";Reactome:R-HSA-2562564 "Caspase-8 processing within TLR4 complex";Reactome:R-HSA-264865 "Caspase-mediated cleavage of Lamin A";Reactome:R-HSA-264871 "Caspase-mediated cleavage of Lamin B1";Reactome:R-HSA-3465448 "Caspase-8 and FLIP(L) processing at DISC";Reactome:R-HSA-350158 "LGMN degrades GC";Reactome:R-HSA-350318 "Caspase-mediated cleavage of vimentin at TNLD (429)";Reactome:R-HSA-350319 "Caspase mediated cleavage of vimentin at IDVD (259)";Reactome:R-HSA-350651 "Caspase-mediated cleavage of MASK";Reactome:R-HSA-351849 "Caspase-mediated cleavage of Etk";Reactome:R-HSA-351871 "Caspase-mediated cleavage of Z0-2";Reactome:R-HSA-351876 "Caspase-mediated cleavage of occludin";Reactome:R-HSA-351877 "Caspase-mediated cleavage of Desmoglein 2";Reactome:R-HSA-351894 "Caspase mediated cleavage of BAP31";Reactome:R-HSA-351901 "Caspase-mediated cleavage of MST3";Reactome:R-HSA-351913 "Caspase-mediated cleavage of TJP1";Reactome:R-HSA-351936 "Caspase-mediated cleavage of claspin";Reactome:R-HSA-352268 "Cleavage of Satb1";Reactome:R-HSA-418845 "Activation of caspase-3";Reactome:R-HSA-418846 "Caspase cleavage of UNC5A";Reactome:R-HSA-418852 "Caspase cleavage of UNC5B";Reactome:R-HSA-448703 "Interleukin-1 family precursors are cleaved by caspase-1";Reactome:R-HSA-5357828 "RIPK1 is cleaved by CASP8";Reactome:R-HSA-5634228 "TRAF1 is cleaved by caspases";Reactome:R-HSA-5660663 "Caspase-8 cleaves IL1B precursor";Reactome:R-HSA-5681987 "LC3 is cleaved by ATG4";Reactome:R-HSA-5682377 "LC3 de-lipidation by ATG4";Reactome:R-HSA-6814387 "CASP14 cleaves filaggrin";Reactome:R-HSA-9012556 "IL37:2x(CASP1(120-197):CASP1(317-404)) cleaves IL37";Reactome:R-HSA-9013895 "Caspase-8 processing within TLR3 complex";Reactome:R-HSA-933532 "Processing of caspases";Reactome:R-HSA-9603534 "Unknown caspase cleaves NTRK3";Reactome:R-HSA-9647632 "CASP3 cleaves GSDME";Reactome:R-HSA-9647680 "CASP1 cleaves GSDMD";Reactome:R-HSA-9647999 "RCE1 cleaves S-Farn proRAS proteins";Reactome:R-HSA-9684273 "3CLp cleaves pp1a";Reactome:R-HSA-9684309 "3CLp cleaves nsp6-11";Reactome:R-HSA-9684321 "nsp3 cleaves nsp1-4";Reactome:R-HSA-9684336 "nsp1-4 cleaves itself";Reactome:R-HSA-9684340 "3CLp cleaves pp1ab";Reactome:R-HSA-9684351 "pp1a cleaves itself";Reactome:R-HSA-9684352 "nsp3-4 cleaves itself";Reactome:R-HSA-9686088 "CASP3 cleaves GSDMD";Reactome:R-HSA-9686930 "RIPK3 is cleaved by CASP8";Reactome:R-HSA-9693929 "RIPK1 variant is not cleaved by CASP8";Reactome:R-HSA-9694338 "nsp1-4 cleaves itself";Reactome:R-HSA-9694377 "pp1a cleaves itself";Reactome:R-HSA-9694441 "3CLp cleaves pp1a";Reactome:R-HSA-9694551 "3CLp cleaves nsp6-11";Reactome:R-HSA-9694601 "nsp3-4 cleaves itself";Reactome:R-HSA-9694625 "nsp3 cleaves nsp1-4";Reactome:R-HSA-9694732 "3CLp cleaves pp1ab";Reactome:R-HSA-9697750 "RIPK1 is cleaved by CASP8:FLIP(L)";Reactome:R-HSA-9710101 "CASP4, CASP5 cleave GSDMD";Reactome:R-HSA-9729704 "SARS-CoV-2 3CLpro dimer cleaves TAB1";Reactome:R-HSA-9729730 "SARS-CoV-2 nsp3 cleaves IRF3";Reactome:R-HSA-9729741 "SARS-CoV-2 3CLpro dimer cleaves NLRP12"	WAS	EC:3.4.22.-;Reactome:R-HSA-114252 "Cleavage of Procaspase-3 by the apoptosome";Reactome:R-HSA-114259 "Cleavage of Procaspase9 to caspase9";Reactome:R-HSA-114261 "Cleavage of Procaspase-7 by the apoptosome";Reactome:R-HSA-1236948 "Antigen processing by cathepsin S in endosoytic vesicle";Reactome:R-HSA-139898 "Caspase-8 activates BID by cleavage";Reactome:R-HSA-139952 "Caspase-8 processing in the DISC";Reactome:R-HSA-1678920 "TLR processing at low pH";Reactome:R-HSA-1678981 "TLR9 processing at neutral pH";Reactome:R-HSA-201595 "Caspase-mediated cleavage of plakophilin-1";Reactome:R-HSA-201603 "Caspase-mediated cleavage of PKC theta";Reactome:R-HSA-201608 "Caspase-mediated cleavage of alpha adducin";Reactome:R-HSA-201611 "Caspase-mediated cleavage of Rock-1";Reactome:R-HSA-201622 "Caspase-mediated cleavage of gelsolin";Reactome:R-HSA-201628 "Caspase-mediated cleavage of vimentin at DSVD (85)";Reactome:R-HSA-201629 "Caspase-mediated cleavage of Tau";Reactome:R-HSA-201630 "Caspase-mediated cleavage of Acinus";Reactome:R-HSA-201631 "Caspase-mediated cleavage of Desmoglein 3";Reactome:R-HSA-201634 "Caspase-mediated cleavage of FADK 1";Reactome:R-HSA-201636 "Caspase-mediated cleavage of Desmoplakin";Reactome:R-HSA-201637 "Caspase-mediated cleavage of plectin-1";Reactome:R-HSA-201639 "Caspase-mediated cleavage of GAS2";Reactome:R-HSA-201640 "Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha";Reactome:R-HSA-2028692 "Cleavage of p-STK4 (p-MST1) by caspase 3";Reactome:R-HSA-2028697 "Cleavage of p-STK3 (p-MST2) by caspase 3";Reactome:R-HSA-202917 "Caspase-mediated cleavage of Desmoglein 1";Reactome:R-HSA-202939 "Caspase-mediated cleavage of E-Cadherin";Reactome:R-HSA-202947 "Caspase mediated cleavage of APC";Reactome:R-HSA-202960 "Caspase mediated cleavage of C-IAP1";Reactome:R-HSA-202966 "Caspase mediated cleavage of HIP-55";Reactome:R-HSA-202967 "Caspase mediated cleavage of alpha-II-Fodrin";Reactome:R-HSA-202969 "Caspase mediated cleavage of beta-catenin";Reactome:R-HSA-211186 "Cleavage of DFF45 (224) by caspase-3";Reactome:R-HSA-211190 "Caspase 3-mediated cleavage of DFF45 (117)";Reactome:R-HSA-211651 "Cleavage of PAK-2 at 212";Reactome:R-HSA-212552 "Caspase 3-mediated cleavage of PKC delta";Reactome:R-HSA-2130336 "Initial proteolyis of Ii by aspartic proteases to lip22";Reactome:R-HSA-2130349 "Generation of CLIP from lip10";Reactome:R-HSA-2130504 "Cleavage of lip22 to lip10";Reactome:R-HSA-2130706 "MHC class II antigen processing";Reactome:R-HSA-2562564 "Caspase-8 processing within TLR4 complex";Reactome:R-HSA-264865 "Caspase-mediated cleavage of Lamin A";Reactome:R-HSA-264871 "Caspase-mediated cleavage of Lamin B1";Reactome:R-HSA-3465448 "Caspase-8 and FLIP(L) processing at DISC";Reactome:R-HSA-350158 "LGMN degrades GC";Reactome:R-HSA-350318 "Caspase-mediated cleavage of vimentin at TNLD (429)";Reactome:R-HSA-350319 "Caspase mediated cleavage of vimentin at IDVD (259)";Reactome:R-HSA-350651 "Caspase-mediated cleavage of MASK";Reactome:R-HSA-351849 "Caspase-mediated cleavage of Etk";Reactome:R-HSA-351871 "Caspase-mediated cleavage of Z0-2";Reactome:R-HSA-351876 "Caspase-mediated cleavage of occludin";Reactome:R-HSA-351877 "Caspase-mediated cleavage of Desmoglein 2";Reactome:R-HSA-351894 "Caspase mediated cleavage of BAP31";Reactome:R-HSA-351901 "Caspase-mediated cleavage of MST3";Reactome:R-HSA-351913 "Caspase-mediated cleavage of TJP1";Reactome:R-HSA-351936 "Caspase-mediated cleavage of claspin";Reactome:R-HSA-352268 "Cleavage of Satb1";Reactome:R-HSA-418845 "Activation of caspase-3";Reactome:R-HSA-418846 "Caspase cleavage of UNC5A";Reactome:R-HSA-418852 "Caspase cleavage of UNC5B";Reactome:R-HSA-448703 "Interleukin-1 family precursors are cleaved by caspase-1";Reactome:R-HSA-5357828 "RIPK1 is cleaved by CASP8";Reactome:R-HSA-5634228 "TRAF1 is cleaved by caspases";Reactome:R-HSA-5660663 "Caspase-8 cleaves IL1B precursor";Reactome:R-HSA-5681987 "LC3 is cleaved by ATG4";Reactome:R-HSA-5682377 "LC3 de-lipidation by ATG4";Reactome:R-HSA-6800797 "The PIDDosome activates CASP2";Reactome:R-HSA-6814387 "CASP14 cleaves filaggrin";Reactome:R-HSA-9012556 "IL37:2x(CASP1(120-197):CASP1(317-404)) cleaves IL37";Reactome:R-HSA-9013895 "Caspase-8 processing within TLR3 complex";Reactome:R-HSA-933532 "Processing of caspases";Reactome:R-HSA-9603534 "Unknown caspase cleaves NTRK3";Reactome:R-HSA-9647632 "CASP3 cleaves GSDME";Reactome:R-HSA-9647680 "CASP1 cleaves GSDMD";Reactome:R-HSA-9647999 "RCE1 cleaves S-Farn proRAS proteins";Reactome:R-HSA-9684273 "3CLp cleaves pp1a";Reactome:R-HSA-9684309 "3CLp cleaves nsp6-11";Reactome:R-HSA-9684321 "nsp3 cleaves nsp1-4";Reactome:R-HSA-9684336 "nsp1-4 cleaves itself";Reactome:R-HSA-9684340 "3CLp cleaves pp1ab";Reactome:R-HSA-9684351 "pp1a cleaves itself";Reactome:R-HSA-9684352 "nsp3-4 cleaves itself";Reactome:R-HSA-9686088 "CASP3 cleaves GSDMD";Reactome:R-HSA-9686930 "RIPK3 is cleaved by CASP8";Reactome:R-HSA-9693929 "RIPK1 variant is not cleaved by CASP8";Reactome:R-HSA-9694338 "nsp1-4 cleaves itself";Reactome:R-HSA-9694377 "pp1a cleaves itself";Reactome:R-HSA-9694441 "3CLp cleaves pp1a";Reactome:R-HSA-9694551 "3CLp cleaves nsp6-11";Reactome:R-HSA-9694601 "nsp3-4 cleaves itself";Reactome:R-HSA-9694625 "nsp3 cleaves nsp1-4";Reactome:R-HSA-9694732 "3CLp cleaves pp1ab";Reactome:R-HSA-9697750 "RIPK1 is cleaved by CASP8:FLIP(L)";Reactome:R-HSA-9710101 "CASP4, CASP5 cleave GSDMD";Reactome:R-HSA-9729704 "SARS-CoV-2 3CLpro dimer cleaves TAB1";Reactome:R-HSA-9729730 "SARS-CoV-2 nsp3 cleaves IRF3";Reactome:R-HSA-9729741 "SARS-CoV-2 3CLpro dimer cleaves NLRP12"
molecular_function	GO:0004619	phosphoglycerate mutase activity
	xrefs	KEGG_REACTION:R01516;Reactome:R-HSA-71445 "PGAM dimers (PGAM1,2) isomerise 2PG to 3PG";Reactome:R-HSA-71654 "3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate";RHEA:15901	WAS	Reactome:R-HSA-71445 "PGAM dimers (PGAM1,2) isomerise 2PG to 3PG";Reactome:R-HSA-71654 "3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate";RHEA:15901
molecular_function	GO:0004674	protein serine/threonine kinase activity
	xrefs	EC:2.7.11.-;MetaCyc:PROTEIN-KINASE-RXN;Reactome:R-HSA-109702 "PDPK1 phosphorylates AKT2";Reactome:R-HSA-109822 "MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1";Reactome:R-HSA-109823 "MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2";Reactome:R-HSA-109860 "MAP2K1 phosphorylates MAPK3";Reactome:R-HSA-109862 "MAP2K2 phosphorylates MAPK1";Reactome:R-HSA-111919 "PKA phosphorylates CREB1";Reactome:R-HSA-111970 "PKC phosphorylates GRK2";Reactome:R-HSA-112342 "Inactivation of MAP2K1 by CDK1";Reactome:R-HSA-112381 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex";Reactome:R-HSA-1168635 "PRKCB (PKC-beta) phosphorylates CARMA1";Reactome:R-HSA-1168638 "Activated IKK phosphorylates I-kappaB";Reactome:R-HSA-1168641 "TAK1 associated with the CBM complex phosphorylates IKKbeta";Reactome:R-HSA-1181149 "ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin";Reactome:R-HSA-1181156 "Type II Activin Receptor (ActRII/ACVR2) phosphorylates Type I Activin Receptor (ActRIB/ACVR1B) in response to NODAL";Reactome:R-HSA-1181355 "Phosphorylation of R-SMAD2/3 by NODAL receptor";Reactome:R-HSA-1225894 "Type II Activin Receptor (ActRIIB/ACVR2B) phosphorylates Type I Activin Receptor (ActRIC/ACVR1C) in response to NODAL";Reactome:R-HSA-1358791 "Phosphorylation of USP8 by P-AKT";Reactome:R-HSA-1362270 "Phosphorylation of LIN52 component of MuvB by DYRK1A";Reactome:R-HSA-139908 "Phosphorylation of DLC2 by MAPK8";Reactome:R-HSA-139918 "Phosphorylation of BIM by JNK";Reactome:R-HSA-1445144 "p-AKT1,p-AKT2 phosphorylates AS160 (TBC1D4)";Reactome:R-HSA-1449597 "p-AKT2 phosphorylates Myosin 5A";Reactome:R-HSA-1454699 "AMPK-alpha2 phosphorylates TBC1D1";Reactome:R-HSA-1458463 "p-AKT2 phosphorylates RGC2";Reactome:R-HSA-1549526 "Phosphorylation of SMAD2,3 by Activin:Activin Receptor";Reactome:R-HSA-156673 "Regulation of KIF23 (MKLP1) by phosphorylation";Reactome:R-HSA-156678 "Activation of Cdc25C";Reactome:R-HSA-156682 "PLK1 phosphorylates NUDC";Reactome:R-HSA-156699 "Inactivation of Wee1 kinase";Reactome:R-HSA-156723 "Regulation of KIF20A (MKL2) by phosphorylation";Reactome:R-HSA-1592233 "p38 MAPK phosphorylates PPARGC1A";Reactome:R-HSA-162363 "p-T309,S474-AKT2:PIP3 phosphorylates PDE3B";Reactome:R-HSA-162657 "Inactivation of Myt1 kinase";Reactome:R-HSA-163010 "Down Regulation of Emi1 through Phosphorylation of Emi1";Reactome:R-HSA-1632857 "ULK1 phosphorylates AMBRA1:BECN1 complex";Reactome:R-HSA-163416 "hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP";Reactome:R-HSA-163418 "perilipin + 2 ATP -> phosphorylated perilipin + 2 ADP";Reactome:R-HSA-1638803 "Phosphorylation of cohesin by PLK1 at centromeres";Reactome:R-HSA-164151 "LKB1 phosphorylates the alpha subunit of AMPK heterotrimer";Reactome:R-HSA-165162 "Phosphorylation of TSC2 by PKB";Reactome:R-HSA-165182 "Phosphorylation of complexed TSC2 by PKB";Reactome:R-HSA-165692 "Phosphorylation of 4E-BP1 by activated mTORC1";Reactome:R-HSA-165718 "mTORC1 phosphorylation of RPS6KB1 (S6K)";Reactome:R-HSA-165726 "Phosphorylation of Ribosomal protein S6 by activated S6K1";Reactome:R-HSA-165758 "Phosphorylation and inactivation of eEF2K by activated S6K1";Reactome:R-HSA-165766 "Phosphorylation and activation of eIF4G by activated S6K1";Reactome:R-HSA-165777 "Phosphorylation and activation of eIF4B by activated S6K1";Reactome:R-HSA-166119 "First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal";Reactome:R-HSA-166245 "Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex";Reactome:R-HSA-166284 "Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP";Reactome:R-HSA-166286 "Multiple IRAK1 autophosphorylation steps";Reactome:R-HSA-167084 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex";Reactome:R-HSA-167098 "Phosphorylation (Ser5) of RNA pol II CTD";Reactome:R-HSA-168053 "Phosphorylated MAPKs phosphorylate ATF-2";Reactome:R-HSA-168140 "Active IKK Complex phosphorylates NF-kappa-B inhibitor";Reactome:R-HSA-168184 "Activated TAK1 mediates phosphorylation of the IKK Complex";Reactome:R-HSA-170055 "Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes";Reactome:R-HSA-170076 "CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes";Reactome:R-HSA-170087 "CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes";Reactome:R-HSA-170116 "Myt-1 mediated phosphorylation of Cyclin A:Cdc2";Reactome:R-HSA-170126 "Phosphorylation of Cyclin B1 in the CRS domain";Reactome:R-HSA-170977 "FRS2 is phosphorylated by active TrkA receptor";Reactome:R-HSA-174119 "Free APC/C phosphorylated by Plk1";Reactome:R-HSA-174174 "Phosphorylation of the Emi1 DSGxxS degron by Plk1";Reactome:R-HSA-176116 "Recruitment and activation of Chk1";Reactome:R-HSA-176298 "Activation of claspin";Reactome:R-HSA-187688 "p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3";Reactome:R-HSA-187949 "CAK-mediated phosphorylation of Cyclin A:Cdk2";Reactome:R-HSA-188350 "CAK-mediated phosphorylation of Cyclin E:Cdk2";Reactome:R-HSA-193647 "IRAK is activated";Reactome:R-HSA-193705 "IKKbeta phosphorylates IkB causing NF-kB to dissociate";Reactome:R-HSA-195275 "Phosphorylation of APC component of the destruction complex";Reactome:R-HSA-195283 "Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3";Reactome:R-HSA-195287 "Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3";Reactome:R-HSA-195300 "Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3";Reactome:R-HSA-195318 "Phosphorylation of beta-catenin at Ser45 by CK1 alpha";Reactome:R-HSA-198270 "PDPK1 phosphorylates AKT at T308";Reactome:R-HSA-198347 "AKT phosphorylates BAD";Reactome:R-HSA-198371 "AKT phosphorylates GSK3";Reactome:R-HSA-198599 "AKT phosphorylates MDM2";Reactome:R-HSA-198609 "AKT phosphorylates TSC2, inhibiting it";Reactome:R-HSA-198611 "AKT phosphorylates IKKalpha";Reactome:R-HSA-198613 "AKT phosphorylates p21Cip1 and p27Kip1";Reactome:R-HSA-198621 "AKT phosphorylates caspase-9";Reactome:R-HSA-198640 "TORC2 (mTOR) phosphorylates AKT at S473";Reactome:R-HSA-198669 "p38MAPK phosphorylates MSK1";Reactome:R-HSA-198731 "ERK1/2 activates ELK1";Reactome:R-HSA-198746 "ERK1/2/5 activate RSK1/2/3";Reactome:R-HSA-198756 "ERK1/2 phosphorylates MSK1";Reactome:R-HSA-199298 "AKT phosphorylates CREB1";Reactome:R-HSA-199299 "AKT phosphorylates FOXO transcription factors";Reactome:R-HSA-199839 "AKT can phosphorylate RSK";Reactome:R-HSA-199863 "AKT can phosphorylate NR4A1 (NUR77)";Reactome:R-HSA-199895 "RSK1/2/3 phosphorylates CREB at Serine 119";Reactome:R-HSA-199910 "MSK1 activates ATF1";Reactome:R-HSA-199917 "MAPKAPK2 phosphorylates CREB at Serine 133";Reactome:R-HSA-199929 "ERK5 activates the transcription factor MEF2";Reactome:R-HSA-199935 "MSK1 activates CREB";Reactome:R-HSA-200143 "AKT phosphorylates AKT1S1 (PRAS40)";Reactome:R-HSA-200421 "Activation of cytosolic AMPK by phosphorylation";Reactome:R-HSA-201677 "Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta";Reactome:R-HSA-201691 "Phosphorylation of LRP5/6 cytoplasmic domain by CSNKI";Reactome:R-HSA-201717 "CSNK2-mediated phosphorylation of DVL";Reactome:R-HSA-202111 "AKT1 phosphorylates eNOS";Reactome:R-HSA-202222 "Phosphorylation of PKC theta";Reactome:R-HSA-202437 "Phosphorylation of CARMA1";Reactome:R-HSA-202459 "Phosphorylation of Bcl10";Reactome:R-HSA-202500 "Activation of IKK complex";Reactome:R-HSA-202510 "Activation of TAK1-TAB2 complex";Reactome:R-HSA-202541 "p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB";Reactome:R-HSA-2028284 "Phosphorylation of STK4 (MST1) and SAV1 by STK4";Reactome:R-HSA-2028555 "Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1)";Reactome:R-HSA-2028583 "Phosphorylation of YAP by LATS2";Reactome:R-HSA-2028589 "Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2)";Reactome:R-HSA-2028591 "Phosphorylation of STK3 (MST2) and SAV1 by STK3";Reactome:R-HSA-2028598 "Phosphorylation of YAP by LATS1";Reactome:R-HSA-2028629 "Phosphorylation of MOB1A and B by p-STK4 (p-MST1)";Reactome:R-HSA-2028635 "Phosphorylation of MOB1A and B by p-STK3 (p-MST2)";Reactome:R-HSA-2028661 "Phosphorylation of WWTR1 (TAZ) by LATS2";Reactome:R-HSA-2028670 "Phosphorylation of MOB1A and B by p-STK4(MST1)/N";Reactome:R-HSA-2028673 "Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N";Reactome:R-HSA-2028675 "Phosphorylation of MOB1A and B by p-STK3(MST2)/N";Reactome:R-HSA-2028679 "Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N";Reactome:R-HSA-2029454 "Autophosphorylation of PAK1";Reactome:R-HSA-2029460 "PAK1 phosphorylates LIMK1";Reactome:R-HSA-2029469 "p-ERK phosphorylates WAVEs and ABI";Reactome:R-HSA-2060328 "Phosphorylation of WWTR1 (TAZ) by LATS1";Reactome:R-HSA-209087 "IKBA is phosphorylated by Phospho IKKB kinase";Reactome:R-HSA-211164 "AKT phosphorylates FOXO1A";Reactome:R-HSA-211583 "Partial autophosphorylation of PAK-2 at  Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197";Reactome:R-HSA-211650 "Autophosphorylation of PAK-2p34 in the activation loop";Reactome:R-HSA-2168079 "MASTL (GWL) phosphorylates ARPP19";Reactome:R-HSA-2176475 "Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9";Reactome:R-HSA-2214351 "PLK1 phosphorylates GORASP1";Reactome:R-HSA-2243938 "AKT1 E17K mutant is phosphorylated by TORC2 complex";Reactome:R-HSA-2243942 "PDPK1 phosphorylates AKT1 E17K mutant";Reactome:R-HSA-2294580 "PLK1 hyperphosphorylates Condensin II complex";Reactome:R-HSA-2396007 "IRF3 is phosphorylated by TBK1";Reactome:R-HSA-2399941 "AKT1 E17K mutant phosphorylates BAD";Reactome:R-HSA-2399966 "AKT1 E17K mutant phosphorylates GSK3";Reactome:R-HSA-2399969 "AKT1 E17K mutant phosphorylates p21Cip1 and p27Kip1";Reactome:R-HSA-2399977 "AKT1 E17K mutant phosphorylates AKT1S1 (PRAS40)";Reactome:R-HSA-2399981 "AKT1 E17K mutant phosphorylates MDM2";Reactome:R-HSA-2399982 "AKT1 E17K mutant phosphorylates TSC2, inhibiting it";Reactome:R-HSA-2399985 "AKT1 E17K mutant phosphorylates caspase-9";Reactome:R-HSA-2399988 "AKT1 E17K mutant phosphorylates NR4A1 (NUR77)";Reactome:R-HSA-2399992 "AKT1 E17K mutant phosphorylates forkhead box transcription factors";Reactome:R-HSA-2399996 "AKT1 E17K mutant phosphorylates CREB1";Reactome:R-HSA-2399999 "AKT1 E17K mutant phosphorylates RSK";Reactome:R-HSA-2400001 "AKT1 E17K mutant phosphorylates CHUK (IKKalpha)";Reactome:R-HSA-2422927 "MAPK3-3 or MAPK1 phosphorylate GORASP2";Reactome:R-HSA-2430535 "MASTL phosphorylates ENSA";Reactome:R-HSA-2466068 "Phosphorylation of cohesin by PLK1 at chromosomal arms";Reactome:R-HSA-2470508 "ACVR2A,B (ActRIIA,B) phosphorylates ACVR1C (ActRIC, ALK7) in response to Activin";Reactome:R-HSA-2529020 "CK2 phosphorylates condensin I subunits";Reactome:R-HSA-2562526 "PLK1 phosphorylates OPTN";Reactome:R-HSA-2574840 "AJUBA facilitates AURKA autophosphorylation";Reactome:R-HSA-2730856 "Autophosphorylation of PAK";Reactome:R-HSA-2730868 "Phosphorylation of MEK7 by MEKK1";Reactome:R-HSA-2730876 "Phosphorylation of IKK-beta by TAK1";Reactome:R-HSA-2730896 "Phosphorylation of MEK4 by MEKK1";Reactome:R-HSA-2730900 "Activation of TAK1 complex bound to pUb-TRAF6";Reactome:R-HSA-2984226 "PLK1 phosphorylates NEK9";Reactome:R-HSA-2984258 "NEK9 phosphorylates NEK6/NEK7";Reactome:R-HSA-2990880 "NEK6/NEK7 phosphorylates NUP98";Reactome:R-HSA-2993898 "VRK1/VRK2 phosphorylate BANF1";Reactome:R-HSA-3000310 "AURKA phosphorylates PLK1";Reactome:R-HSA-3000327 "PLK1 phosphorylates BORA";Reactome:R-HSA-3132737 "MAPKs phosphorylate ETS1 and ETS2";Reactome:R-HSA-3209160 "Activated ERKs phosphorylate ERF";Reactome:R-HSA-3222006 "STK11 (LKB1) phosphorylates NUAK1";Reactome:R-HSA-3222020 "NUAK1 phosphorylates TP53";Reactome:R-HSA-3228469 "MAP3K5 phosphorylates MKK3 and MKK6";Reactome:R-HSA-3229102 "p-MAPKAPK3 phosphorylates BMI1";Reactome:R-HSA-3229152 "MAP3K5 (ASK1) phosphorylates MAP2K4 (SEK1)";Reactome:R-HSA-3239014 "MAPKAPK5 phosphorylates TP53";Reactome:R-HSA-3239019 "Active p38 MAPK phosphorylates MAPKAPK5";Reactome:R-HSA-3249371 "TBK1 phosphorylates STAT6 at Ser407";Reactome:R-HSA-3371435 "Constitutive phosphorylation by GSK3";Reactome:R-HSA-3371531 "Constitutive phosphorylation  by pERK1/2";Reactome:R-HSA-3371567 "DBC1 is phosphorylated by ATM/ART";Reactome:R-HSA-349426 "Phosphorylation of MDM4 by CHEK2";Reactome:R-HSA-349444 "Phosphorylation of COP1 at Ser-387  by ATM";Reactome:R-HSA-349455 "Phosphorylation of MDM4 by ATM";Reactome:R-HSA-374696 "Phosphorylation of L1 by p90rsk";Reactome:R-HSA-3769394 "AKT phosphorylates CBY1";Reactome:R-HSA-377186 "Activated Akt1 phosphorylates AKT1S1 (PRAS40)";Reactome:R-HSA-3772435 "WNT signaling stimulates CSNK1-dependent phosphorylation of DVL";Reactome:R-HSA-380272 "Plk1-mediated phosphorylation of Nlp";Reactome:R-HSA-381091 "IRE1 dimer autophosphorylates";Reactome:R-HSA-381111 "EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK";Reactome:R-HSA-3857328 "RPS6KA1/2/3 phosphorylates CEBPB on S321";Reactome:R-HSA-3857329 "MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB";Reactome:R-HSA-3858480 "WNT-dependent phosphorylation of DVL";Reactome:R-HSA-389756 "AKT interacts and phosphorylates Cot";Reactome:R-HSA-392752 "Phosphorylation of L1 by CK-II";Reactome:R-HSA-3928577 "ROCK phosphorylates LIMK1,2";Reactome:R-HSA-3928608 "LIMK phosphorylates CFL1, inactivating it";Reactome:R-HSA-3928616 "Activated ROCK phosphorylates MRLCs";Reactome:R-HSA-3928620 "PAK1 autophosphorylates";Reactome:R-HSA-3928625 "PAKs autophosphorylate";Reactome:R-HSA-3928640 "PAKs phosphorylate MLC";Reactome:R-HSA-399939 "Autophosphorylation of PAK";Reactome:R-HSA-399944 "Phosphorylation of CRMPs by Cdk5";Reactome:R-HSA-399950 "Phosphorylation of cofilin by LIMK-1";Reactome:R-HSA-399951 "Phosphorylation of CRMPs by GSK3beta";Reactome:R-HSA-399952 "Phosphorylation of LIMK-1 by PAK";Reactome:R-HSA-399978 "Protein kinase C, alpha type phosphorylates MARCKS";Reactome:R-HSA-400382 "CSNK1E,CSNK1D phosphorylate CRY and PER proteins";Reactome:R-HSA-4088134 "PLK1 phosphorylates FOXM1";Reactome:R-HSA-419083 "Myosin phosphatase inactivation by ROCK";Reactome:R-HSA-419087 "LIM kinase phosphorylation by ROCK";Reactome:R-HSA-419197 "Myosin regulatory light chain phosphorylation by ROCK";Reactome:R-HSA-419644 "Transphosphorylation of pLIMK1";Reactome:R-HSA-428961 "Phosphorylation of cPLA2 by MAPK p38 alpha";Reactome:R-HSA-429016 "ALOX5 is phosphorylated by MAPKAP2";Reactome:R-HSA-429714 "CSNK1G2 phosphorylates p-CERT1-2";Reactome:R-HSA-432110 "Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding";Reactome:R-HSA-4332358 "Dissociation of CaM and CAMK2 autophosphorylation";Reactome:R-HSA-4332363 "Autophosphorylation and activation of CAMK2";Reactome:R-HSA-4332388 "Activation of MAP3K7 in response to WNT";Reactome:R-HSA-4411383 "NLK phosphorylates TCF/LEF";Reactome:R-HSA-4411402 "Activation of NLK";Reactome:R-HSA-442724 "Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs)";Reactome:R-HSA-442739 "PDPK1 phosphorylates RSKs";Reactome:R-HSA-442832 "PAK phosphorylates cortactin";Reactome:R-HSA-445072 "Interaction of PAK1 with Rac1-GTP";Reactome:R-HSA-446694 "IRAK4 phosphorylates IRAK1";Reactome:R-HSA-446701 "IRAK4-activated IRAK1 autophosphorylates";Reactome:R-HSA-448948 "Phosphorylation of E proteins by p38 MAPK";Reactome:R-HSA-448955 "Phosphorylation of MEF2 proteins by p38";Reactome:R-HSA-450222 "Active p38 MAPK phosphorylates MAPKAPK2 or 3";Reactome:R-HSA-450325 "c-FOS activation by phospho ERK1/2";Reactome:R-HSA-450337 "Activated TAK1 phosphorylates MKK4/MKK7";Reactome:R-HSA-450346 "activated human TAK1 phosphorylates MKK3/MKK6";Reactome:R-HSA-450463 "MK2 phosphorylates ZFP36 (Tristetraproline, TTP)";Reactome:R-HSA-450474 "MK2 phosphorylates BRF1";Reactome:R-HSA-450490 "Protein Kinase B/Akt phosphorylates BRF1";Reactome:R-HSA-450499 "Protein Kinase B (AKT) phosphorylates KSRP";Reactome:R-HSA-450827 "hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2";Reactome:R-HSA-451152 "MAP kinase p38 phosphorylates KSRP";Reactome:R-HSA-4551570 "VANGL2 is phosphorylated in response to WNT5A";Reactome:R-HSA-4608825 "DVL2 is phosphorylated after WNT5A binding to FZD";Reactome:R-HSA-4793911 "MAPKAPK2 phosphorylates HSF1";Reactome:R-HSA-5082387 "Phosphorylation of HSF1 at Ser230 induces transactivation";Reactome:R-HSA-5082405 "Phosphorylation of HSF1 at Ser326 induces transactivation";Reactome:R-HSA-5213464 "RIPK1 is phosphorylated";Reactome:R-HSA-5213466 "RIPK3 is phosphorylated";Reactome:R-HSA-5218814 "PAK2 autophorylates";Reactome:R-HSA-5218821 "PDK1 phosphorylates PKC";Reactome:R-HSA-5218826 "Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732";Reactome:R-HSA-5218854 "p-Y420-FYN is phosphorylated on S21";Reactome:R-HSA-5218906 "RIPK3 phosphorylates MLKL";Reactome:R-HSA-5218916 "p-MAPK2/3 phosphorylates HSP27";Reactome:R-HSA-5228811 "NFKBIA variant is not phosphorylated within IkBA:NF-kappaB";Reactome:R-HSA-5229343 "AXIN is phosphorylated in the destruction complex";Reactome:R-HSA-5260201 "p-AKT2 phosphorylates C2CD5";Reactome:R-HSA-5357472 "PAK1-3 autophosphorylates";Reactome:R-HSA-5357477 "PAK1-3 phosphorylates VE-cadherin";Reactome:R-HSA-5357831 "CHUK, IKBKB phosphorylate CYLD at S418";Reactome:R-HSA-5578777 "DMPK phosphorylates PLN";Reactome:R-HSA-5607722 "Active NIK phosphorylates IKKA dimer";Reactome:R-HSA-5607726 "Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB";Reactome:R-HSA-5607732 "K63polyUb-TAK1 autophosphorylates";Reactome:R-HSA-5607742 "K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta";Reactome:R-HSA-5610718 "CK1 phosphorylates p-GLI2";Reactome:R-HSA-5610722 "CK1 phosphorylates p-GLI3";Reactome:R-HSA-5610730 "GSK3 phosphorylates p-GLI2";Reactome:R-HSA-5610732 "GSK3 phosphorylates p-GLI3";Reactome:R-HSA-5624473 "Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit";Reactome:R-HSA-5624492 "PAK phosphorylates p21 RAF1 on S338";Reactome:R-HSA-5627775 "Autophosphorylation of PAK1,2,3";Reactome:R-HSA-5632670 "CSNK1A1 phosphorylates SMO dimer";Reactome:R-HSA-5632672 "ADRBK1 phosphorylates SMO dimer";Reactome:R-HSA-5635841 "GLI proteins are phosphorylated";Reactome:R-HSA-5635842 "ULK3 phosphorylates GLI";Reactome:R-HSA-5665868 "AMPK (complex) phosphorylates ULK1 (complex)";Reactome:R-HSA-5666160 "AURKB phosphorylates DIAPH2-2 at kinetochores";Reactome:R-HSA-5668545 "NIK autophosphorylates on T559";Reactome:R-HSA-5668932 "PAK2 phosphorylates myosin regulatory light chain (MRLC)";Reactome:R-HSA-5668947 "PAK1 phosphorylates myosin phosphatase";Reactome:R-HSA-5668984 "PAK1 or PAK2 phosphorylates MYLK";Reactome:R-HSA-5669250 "PAK1 phosphorylates FLNA";Reactome:R-HSA-5671763 "p-T774-PKN1 phosphorylates PPP1R14A";Reactome:R-HSA-5671919 "Activated CIT phosphorylates MRLCs";Reactome:R-HSA-5672008 "Thr-180 of ULK1 is phosphorylated";Reactome:R-HSA-5672010 "Active MTORC1 phosphorylates ULK1";Reactome:R-HSA-5672828 "mTORC1 phosphorylates AKT1S1";Reactome:R-HSA-5672948 "MARK3 phosphorylates KSR1";Reactome:R-HSA-5672973 "MAP2Ks phosphorylate MAPKs";Reactome:R-HSA-5672978 "RAF phosphorylates MAP2K dimer";Reactome:R-HSA-5674496 "Activated MAPKs phosphorylate MAP2K1";Reactome:R-HSA-5675194 "Activated MAPK phosphorylates RAF1";Reactome:R-HSA-5675198 "Activated MAPKs phosphorylate BRAF";Reactome:R-HSA-5675868 "ULK1 phosphorylates ATG13 and RB1CC1";Reactome:R-HSA-5679205 "ULK1 phosphorylates Beclin-1";Reactome:R-HSA-5682026 "MRN bound to shortened telomeres activates ATM";Reactome:R-HSA-5682101 "PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer";Reactome:R-HSA-5682598 "ATM phosphorylates HERC2";Reactome:R-HSA-5682983 "ATM phosphorylates WHSC1";Reactome:R-HSA-5683425 "ATM phosphorylates TP53BP1 at DNA DSBs";Reactome:R-HSA-5683792 "p-T68-CHEK2 autophosphorylates";Reactome:R-HSA-5683801 "CHEK2 phosphorylates BRCA1";Reactome:R-HSA-5683964 "ATM phosphorylates EYA1-4";Reactome:R-HSA-5684096 "CDK2 phosphorylates RBBP8";Reactome:R-HSA-5684140 "ATM phosphorylates RBBP8";Reactome:R-HSA-5684887 "Activation of CHEK1 at resected DNA DSBs";Reactome:R-HSA-5685156 "ATR phosphorylates RPA2";Reactome:R-HSA-5685230 "CHEK1 phosphorylates RAD51";Reactome:R-HSA-5685242 "CHEK1 phosphorylates BRCA2";Reactome:R-HSA-5686578 "Activated ATM phosphorylates ABL1";Reactome:R-HSA-5686704 "Activated ATM phosphorylates DCLRE1C";Reactome:R-HSA-5687086 "PAK1,2,3 phosphorylates MAPK6,4";Reactome:R-HSA-5687090 "p-S MAPK6 phosphorylates NCOA3";Reactome:R-HSA-5687094 "p-S MAPK6,4 phosphorylate MAPKAPK5";Reactome:R-HSA-5687101 "p-T182 MAPKAPK5 phosphorylates FOXO3";Reactome:R-HSA-5687121 "p-S MAPKAPK5 phosphorylates HSPB1";Reactome:R-HSA-5687183 "PRKDC phosphorylates DCLRE1C at DNA DSBs";Reactome:R-HSA-5690250 "p-T182-MAPKAPK5 phoshphorylates DNAJB1";Reactome:R-HSA-5692768 "MAPKAPK5 phosphorylates KALRN";Reactome:R-HSA-5692775 "SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs";Reactome:R-HSA-5692779 "p-T182 MAPKAPK5 phosphorylates FOXO1";Reactome:R-HSA-5693536 "ATM phosphorylates MDC1";Reactome:R-HSA-5693540 "MRN activates ATM";Reactome:R-HSA-5693549 "ATM phosphorylates histone H2AFX on S139 at DNA DSBs";Reactome:R-HSA-5693551 "Phosphorylation of BRCA1-A complex at multiple sites by ATM";Reactome:R-HSA-5693575 "DNA-PKcs autophosphorylates";Reactome:R-HSA-5693598 "ATM phosphorylates NBN";Reactome:R-HSA-5693609 "ATM phosphorylates TP53 at S15";Reactome:R-HSA-5694441 "CSNK1D phosphorylates SEC23";Reactome:R-HSA-6788392 "ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA";Reactome:R-HSA-6795290 "TORC2 complex phosphorylates SGK1";Reactome:R-HSA-6795460 "SGK1 phosphorylates MDM2";Reactome:R-HSA-6795473 "PDPK1 phosphorylates SGK1";Reactome:R-HSA-6798372 "ATM phosphorylates DYRK2";Reactome:R-HSA-6798374 "DYRK2 phosphorylates TP53";Reactome:R-HSA-6799097 "ATM phosphorylates ZNF420";Reactome:R-HSA-6799246 "CHEK1 phosphorylates TP53";Reactome:R-HSA-6799332 "ATR phosphorylates TP53";Reactome:R-HSA-6799409 "HIPK2 phosphorylates TP53";Reactome:R-HSA-6800490 "ATM phosphorylates PIDD1";Reactome:R-HSA-6801666 "PLK2 phosphorylates CENPJ";Reactome:R-HSA-6801675 "PLK2 phosphorylates NPM1";Reactome:R-HSA-6802911 "High kinase activity BRAF complexes phosphorylate MAP2Ks";Reactome:R-HSA-6802919 "RAS:GTP:moderate kinase activity p-RAF complexes phosphorylate MAP2Ks";Reactome:R-HSA-6802926 "Mutant RAS:p-RAF complexes phosphorylate MAP2Ks";Reactome:R-HSA-6802933 "p-BRAF and RAF fusion dimers phosphorylate MAP2Ks";Reactome:R-HSA-6802935 "MAPKs are phosphorylated downstream of BRAF and RAF fusion dimers";Reactome:R-HSA-6802943 "RAS:GTP:inactive p-RAF complexes phosphorylate MAP2Ks";Reactome:R-HSA-6802973 "PLK3 phosphorylates CDC25C";Reactome:R-HSA-6804266 "CHEK2 phosphorylates TTC5";Reactome:R-HSA-6804276 "ATM phosphorylates TTC5";Reactome:R-HSA-6804955 "ATM phosphorylates MDM2";Reactome:R-HSA-6805059 "CK2:FACT phosphorylates TP53";Reactome:R-HSA-6805103 "AURKA phosphorylates TP53";Reactome:R-HSA-6805126 "AURKB phosphorylates TP53";Reactome:R-HSA-6805276 "CDK5 phosphorylates TP53";Reactome:R-HSA-6805285 "PLK3 phosphorylates TP53";Reactome:R-HSA-6805399 "TAF1 phosphorylates TP53";Reactome:R-HSA-6805479 "TP53RK phosphorylates TP53";Reactome:R-HSA-6805640 "AKT phosphorylates KAT6A";Reactome:R-HSA-6805785 "AKT phosphorylates PHF20";Reactome:R-HSA-6810233 "CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter";Reactome:R-HSA-6811454 "MAPKs phosphorylate PP2A";Reactome:R-HSA-6814409 "CK2 phosphorylates PDCL";Reactome:R-HSA-69604 "Phosphorylation of Cdc25A at Ser-123 by Chk1";Reactome:R-HSA-69608 "Phosphorylation of Cdc25A at Ser-123 by Chk2";Reactome:R-HSA-69685 "CHEK2 phosphorylates TP53";Reactome:R-HSA-69891 "Phosphorylation and activation of CHEK2 by ATM";Reactome:R-HSA-75010 "Phosphorylation of Cdc25C at Ser 216 by Chk1";Reactome:R-HSA-75028 "Phosphorylation of Wee1 kinase by Chk1";Reactome:R-HSA-75809 "Phosphorylation of Cdc25C at Ser216 by CHEK2";Reactome:R-HSA-75820 "Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta";Reactome:R-HSA-77071 "Phosphorylation (Ser5) of RNA pol II CTD";Reactome:R-HSA-8850945 "Casein kinase II phosphorylates PTEN";Reactome:R-HSA-8852306 "Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends";Reactome:R-HSA-8852317 "PLK1 phosphorylates GTSE1";Reactome:R-HSA-8853419 "TPX2 promotes AURKA autophosphorylation";Reactome:R-HSA-8853444 "AURKA phosphorylates PHLDA1";Reactome:R-HSA-8854908 "PKA phosphorylates RET:GDNF:GFRA dimer";Reactome:R-HSA-8856813 "AAK1 phosphorylates AP-2 mu subunit at T156";Reactome:R-HSA-8863007 "p25-bound CDK5 phosphorylates CDC25B";Reactome:R-HSA-8863011 "p25-bound CDK5 phosphorylates CDC25C";Reactome:R-HSA-8863014 "p25-bound CDK5 phosphorylates CDC25A";Reactome:R-HSA-8863895 "IKKB phosphorylates SNAP23";Reactome:R-HSA-8868118 "MAPK12 phosphorylates PTPN3";Reactome:R-HSA-8868260 "CDK5:p25 phosphorylates GOLGA2";Reactome:R-HSA-8868340 "CDK5:p25 phosphorylates lamin B1";Reactome:R-HSA-8868344 "CDK5:p25 phosphorylates lamin A";Reactome:R-HSA-8868567 "CDK5:p25 phosphorylates PRDX1";Reactome:R-HSA-8868573 "CDK5:p25 phosphorylates PRDX2";Reactome:R-HSA-8868666 "CDK5:p25 phosphorylates JUN";Reactome:R-HSA-8870558 "CDK5:p25 phosphorylates FOXO3";Reactome:R-HSA-8873929 "Casein kinase II phosphorylates STARD10";Reactome:R-HSA-8876446 "p-ULK1 phosphorylates DENND3";Reactome:R-HSA-8877691 "MAP2K6 phosphorylates PIP4K2B";Reactome:R-HSA-8878050 "HIPK2 phosphorylates RUNX1 and EP300";Reactome:R-HSA-8878054 "HIPK2 phosphorylates RUNX1";Reactome:R-HSA-8932322 "CK2 phosphorylates NFE2L2";Reactome:R-HSA-8933446 "Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling";Reactome:R-HSA-8939963 "Activated AKT phosphorylates RUNX2";Reactome:R-HSA-8940100 "CDK1 phosphorylates VCPIP1";Reactome:R-HSA-8942836 "CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6";Reactome:R-HSA-8944454 "mTORC1 phosphorylates MAF1";Reactome:R-HSA-8948039 "FUNDC1 is phosphorylated by CK2";Reactome:R-HSA-8948146 "FUNDC1 is phosphorylated by ULK1 at Ser17";Reactome:R-HSA-8948757 "AKT phosphorylates MKRN1";Reactome:R-HSA-8952289 "FAM20C phosphorylates FAM20C substrates";Reactome:R-HSA-9007539 "CHEK1 phosphorylates E2F6";Reactome:R-HSA-9008480 "GSK3B phosphorylates RUNX2";Reactome:R-HSA-9008822 "PPM1D dephosphorylates RUNX2";Reactome:R-HSA-9009208 "Activated ERKs phosphorylate RUNX2";Reactome:R-HSA-9012319 "p-TEFb phosphorylates serine 2 in RNA polymerase II CTD";Reactome:R-HSA-9013978 "Phosphorylation of IRF-3/IRF7 and their release from the activated TLR3 complex";Reactome:R-HSA-9022314 "HIPK2 phosphorylates MECP2";Reactome:R-HSA-9023132 "AURKB phosphorylates MECP2 at S423";Reactome:R-HSA-9032751 "Estrogen-independent phosphorylation of ESR1 S118 by MAPK1 and MAPK3";Reactome:R-HSA-9032863 "CDK5 phosphorylates NTRK2";Reactome:R-HSA-912470 "ATR phosphorylates Histone H2A.X at unsynapsed regions";Reactome:R-HSA-913996 "PKA/PKG phosphorylate Rap1GAP2";Reactome:R-HSA-918229 "Phosphorylation and release of IRF3/IRF7";Reactome:R-HSA-933525 "Phosphorylation and release of IRF7";Reactome:R-HSA-934559 "SPRY2 is phosphorylated by phosphorylated MNK1";Reactome:R-HSA-936951 "Activation of TAK1 complex bound to activated TLR4 complex";Reactome:R-HSA-937022 "IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP";Reactome:R-HSA-937059 "Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex";Reactome:R-HSA-9604328 "AKT1 phosphorylates NOTCH4";Reactome:R-HSA-9610153 "Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF";Reactome:R-HSA-9610156 "MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF";Reactome:R-HSA-9610163 "BRAF autophosphorylates downstream of RAP1 and NGF";Reactome:R-HSA-9612501 "SGK phosphorylates CREB1";Reactome:R-HSA-9612509 "SGK phosphorylates SRF";Reactome:R-HSA-9612980 "BRAF in Rap1-GTP complex:BRAF complex autophosphorylates";Reactome:R-HSA-9613530 "PRKAA2 phosphorylates PLINs";Reactome:R-HSA-9619515 "AMPK phosphorylates MAPT";Reactome:R-HSA-9619843 "ERKs phosphorylate RSKs";Reactome:R-HSA-9620004 "RSKs autophosphorylate";Reactome:R-HSA-9624526 "AKT phosphorylates FOXO3 downstream of ESR1 and EGFR";Reactome:R-HSA-9626880 "MAPK11 or MAPK14 phosphorylates NCF1 at Ser345";Reactome:R-HSA-9627089 "CASP9 is phosphorylated at T412";Reactome:R-HSA-9632868 "CDKN1B is phosphorylated in response to estrogen";Reactome:R-HSA-9633008 "p-T899-EIF2AK4 (GCN2) phosphorylates EIF2AS1";Reactome:R-HSA-9633742 "EIF2AK4 (GCN2) dimer autophosphorylates";Reactome:R-HSA-9634702 "LINC01139 promotes phosphorylation of HIF1A by LRRK2";Reactome:R-HSA-9645535 "ALPK1 phosphorylates TIFA";Reactome:R-HSA-9648089 "NEK6 and NEK7 phosphorylate EML4";Reactome:R-HSA-9648883 "p-T-EIF2AK1:ferriheme dimer autophosphorylates";Reactome:R-HSA-9648888 "p-T,T486,T488-EIF2AK1 phosphorylates EIF2S1 (eIF2-alpha)";Reactome:R-HSA-9652165 "MAP2K mutants constitutively phosphorylate MAPKs";Reactome:R-HSA-9653503 "KRAS4B is phosphorylated on serine 181";Reactome:R-HSA-9656214 "MAP2Ks phosphorylate MAPKs downstream of RAF1 mutants";Reactome:R-HSA-9656215 "RAF1 mutant complexes phosphorylate MAP2K dimer";Reactome:R-HSA-9662823 "PLK2, MAPK14 phosphorylate ADAM17";Reactome:R-HSA-9673346 "Unknown kinase phosphorylates p-DVL";Reactome:R-HSA-9683664 "GSK3 phosphorylates Nucleoprotein";Reactome:R-HSA-9699579 "AKT phosphorylates FOXO3 downstream of FLT3";Reactome:R-HSA-9705320 "TBK1, IKBKE are autophosphorylated at Ser172";Reactome:R-HSA-9705323 "Phosphorylation of TBK1/IKBKE";Reactome:R-HSA-9725030 "MAPK1 phsophorylates ZC3HCF1 in a NPM-ALK-dependent manner";Reactome:R-HSA-9729260 "GSK3 phosphorylates nucleoprotein";Reactome:R-HSA-9729300 "Unknown kinase phosphorylates nucleoprotein";Reactome:R-HSA-9729318 "CSNK1A1 phosphorylates nucleoprotein";Reactome:R-HSA-9731111 "MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3";Reactome:R-HSA-9734547 "JAK2-activated MAPKs phosphorylate YBX1";Reactome:R-HSA-975125 "Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9";Reactome:R-HSA-975134 "Second phosphorylation of IRAK1 by IRAK4 bound to MyD88;Reactome:R-HSA-975160 "Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:activated TLR 7/8 or 9";Reactome:R-HSA-975170 "IRAK4 autophosphorylation in the complex with MyD88:activated TLR 7/8 or 9";Reactome:R-HSA-975180 "First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9";Reactome:R-HSA-9758486 "Unknown kinase phosphorylates 9b";Reactome:R-HSA-975853 "Multiple IRAK1 autophosphorylation within the complex p-IRAK4:oligo MyD88:activated TLR";Reactome:R-HSA-975861 "Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomerl:activated TLR5 or 10 complex";Reactome:R-HSA-975865 "IRAK4 autophosphorylation within the complex activated TLR:MyD88";Reactome:R-HSA-975874 "Second phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR complex";Reactome:R-HSA-975878 "First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR";Reactome:R-HSA-9762094 "GSK3B phosphorylates p-NFE2L2";Reactome:R-HSA-9766532 "SQSTM1 oligomer is phosphorylated";Reactome:R-HSA-9769115 "MAPK1,(MAPK3) phosphorylates NPAS4";Reactome:R-HSA-9773803 "Active IKBKB phosphorylates NF-kappa-B inhibitor";Reactome:R-HSA-9796067 "PRKAA2 phosphorylates nuclear NFE2L2";Reactome:R-HSA-9796081 "EIF2AK3 phosphorylates NFE2L2";Reactome:R-HSA-9815501 "MAPKAPK2 phosphorylates RIPK1 at S320";Reactome:R-HSA-9817397 "TBK1, IKBKE phosphorylate RIPK1 at T189";Reactome:R-HSA-9818789 "CHUK, IKBKB phosphorylate RIPK1 at S25";Reactome:R-HSA-9819106 "ULK1 phosphorylates RIPK1 at S357";Reactome:R-HSA-9824582 "MAPK1 phosphorylates SOX10";Reactome:R-HSA-9824897 "p-S-TBK1 phosphorylates OPTN";Reactome:R-HSA-9824977 "MAPK1-dependent phosphorylation of MITF-M";Reactome:R-HSA-9824994 "RPS6KA1-dependent phosphorylation of MITF-M";Reactome:R-HSA-9824995 "GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405";Reactome:R-HSA-9824999 "GSK3B phosphorylates p-S73 MITF-M at residue S69";Reactome:R-HSA-9825704 "AKT3 phosphorylates TBX3";Reactome:R-HSA-9831514 "CK2 phosphorylates nascent P";Reactome:R-HSA-9831712 "M dimer is phosphorylated";Reactome:R-HSA-9832782 "p-S232-S237-P is further phosphorylated";Reactome:R-HSA-9834076 "PINK1 is autophosphorylated";Reactome:R-HSA-9834945 "PINK1 phosphorylates Ub on MOM proteins";Reactome:R-HSA-9835011 "PINK1 phosphorylates PRKN at S65";Reactome:R-HSA-9839363 "TGFBR3 phosphorylation by TGFBR2 complex";Reactome:R-HSA-9851972 "PLK1 phosphorylates FIRRM at S43";Reactome:R-HSA-9853369 "PLK1 phosphorylates FIRMM at S744";Reactome:R-HSA-9855910 "USF1 is phosphorylated by p-MAPK14";Reactome:R-HSA-9860292 "Activated IKBKB phosphorylates IRF5";Reactome:R-HSA-9860785 "PDPK1 (PDK1) phosphorylates PKN2 on threonine-816";Reactome:R-HSA-9860800 "mTORC2 phosphorylates AKT1 on serine-473";Reactome:R-HSA-9861642 "NEK1 phosphorylates ME1"	WAS	EC:2.7.11.1;MetaCyc:PROTEIN-KINASE-RXN;Reactome:R-HSA-109702 "PDPK1 phosphorylates AKT2";Reactome:R-HSA-109822 "MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1";Reactome:R-HSA-109823 "MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2";Reactome:R-HSA-109860 "MAP2K1 phosphorylates MAPK3";Reactome:R-HSA-109862 "MAP2K2 phosphorylates MAPK1";Reactome:R-HSA-111919 "PKA phosphorylates CREB1";Reactome:R-HSA-111970 "PKC phosphorylates GRK2";Reactome:R-HSA-112342 "Inactivation of MAP2K1 by CDK1";Reactome:R-HSA-112381 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex";Reactome:R-HSA-1168635 "PRKCB (PKC-beta) phosphorylates CARMA1";Reactome:R-HSA-1168638 "Activated IKK phosphorylates I-kappaB";Reactome:R-HSA-1168641 "TAK1 associated with the CBM complex phosphorylates IKKbeta";Reactome:R-HSA-1181149 "ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin";Reactome:R-HSA-1181156 "Type II Activin Receptor (ActRII/ACVR2) phosphorylates Type I Activin Receptor (ActRIB/ACVR1B) in response to NODAL";Reactome:R-HSA-1181355 "Phosphorylation of R-SMAD2/3 by NODAL receptor";Reactome:R-HSA-1225894 "Type II Activin Receptor (ActRIIB/ACVR2B) phosphorylates Type I Activin Receptor (ActRIC/ACVR1C) in response to NODAL";Reactome:R-HSA-1358791 "Phosphorylation of USP8 by P-AKT";Reactome:R-HSA-1362270 "Phosphorylation of LIN52 component of MuvB by DYRK1A";Reactome:R-HSA-139908 "Phosphorylation of DLC2 by MAPK8";Reactome:R-HSA-139918 "Phosphorylation of BIM by JNK";Reactome:R-HSA-1445144 "p-AKT1,p-AKT2 phosphorylates AS160 (TBC1D4)";Reactome:R-HSA-1449597 "p-AKT2 phosphorylates Myosin 5A";Reactome:R-HSA-1454699 "AMPK-alpha2 phosphorylates TBC1D1";Reactome:R-HSA-1458463 "p-AKT2 phosphorylates RGC2";Reactome:R-HSA-1549526 "Phosphorylation of SMAD2,3 by Activin:Activin Receptor";Reactome:R-HSA-156673 "Regulation of KIF23 (MKLP1) by phosphorylation";Reactome:R-HSA-156678 "Activation of Cdc25C";Reactome:R-HSA-156682 "PLK1 phosphorylates NUDC";Reactome:R-HSA-156699 "Inactivation of Wee1 kinase";Reactome:R-HSA-156723 "Regulation of KIF20A (MKL2) by phosphorylation";Reactome:R-HSA-1592233 "p38 MAPK phosphorylates PPARGC1A";Reactome:R-HSA-162363 "p-T309,S474-AKT2:PIP3 phosphorylates PDE3B";Reactome:R-HSA-162657 "Inactivation of Myt1 kinase";Reactome:R-HSA-163010 "Down Regulation of Emi1 through Phosphorylation of Emi1";Reactome:R-HSA-1632857 "ULK1 phosphorylates AMBRA1:BECN1 complex";Reactome:R-HSA-163416 "hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP";Reactome:R-HSA-163418 "perilipin + 2 ATP -> phosphorylated perilipin + 2 ADP";Reactome:R-HSA-1638803 "Phosphorylation of cohesin by PLK1 at centromeres";Reactome:R-HSA-164151 "LKB1 phosphorylates the alpha subunit of AMPK heterotrimer";Reactome:R-HSA-165162 "Phosphorylation of TSC2 by PKB";Reactome:R-HSA-165182 "Phosphorylation of complexed TSC2 by PKB";Reactome:R-HSA-165692 "Phosphorylation of 4E-BP1 by activated mTORC1";Reactome:R-HSA-165718 "mTORC1 phosphorylation of RPS6KB1 (S6K)";Reactome:R-HSA-165726 "Phosphorylation of Ribosomal protein S6 by activated S6K1";Reactome:R-HSA-165758 "Phosphorylation and inactivation of eEF2K by activated S6K1";Reactome:R-HSA-165766 "Phosphorylation and activation of eIF4G by activated S6K1";Reactome:R-HSA-165777 "Phosphorylation and activation of eIF4B by activated S6K1";Reactome:R-HSA-166119 "First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal";Reactome:R-HSA-166245 "Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex";Reactome:R-HSA-166284 "Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP";Reactome:R-HSA-166286 "Multiple IRAK1 autophosphorylation steps";Reactome:R-HSA-167084 "Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex";Reactome:R-HSA-167098 "Phosphorylation (Ser5) of RNA pol II CTD";Reactome:R-HSA-168053 "Phosphorylated MAPKs phosphorylate ATF-2";Reactome:R-HSA-168140 "Active IKK Complex phosphorylates NF-kappa-B inhibitor";Reactome:R-HSA-168184 "Activated TAK1 mediates phosphorylation of the IKK Complex";Reactome:R-HSA-170055 "Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes";Reactome:R-HSA-170076 "CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes";Reactome:R-HSA-170087 "CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes";Reactome:R-HSA-170116 "Myt-1 mediated phosphorylation of Cyclin A:Cdc2";Reactome:R-HSA-170126 "Phosphorylation of Cyclin B1 in the CRS domain";Reactome:R-HSA-170977 "FRS2 is phosphorylated by active TrkA receptor";Reactome:R-HSA-174119 "Free APC/C phosphorylated by Plk1";Reactome:R-HSA-174174 "Phosphorylation of the Emi1 DSGxxS degron by Plk1";Reactome:R-HSA-176116 "Recruitment and activation of Chk1";Reactome:R-HSA-176298 "Activation of claspin";Reactome:R-HSA-187688 "p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3";Reactome:R-HSA-187949 "CAK-mediated phosphorylation of Cyclin A:Cdk2";Reactome:R-HSA-188350 "CAK-mediated phosphorylation of Cyclin E:Cdk2";Reactome:R-HSA-193647 "IRAK is activated";Reactome:R-HSA-193705 "IKKbeta phosphorylates IkB causing NF-kB to dissociate";Reactome:R-HSA-195275 "Phosphorylation of APC component of the destruction complex";Reactome:R-HSA-195283 "Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3";Reactome:R-HSA-195287 "Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3";Reactome:R-HSA-195300 "Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3";Reactome:R-HSA-195318 "Phosphorylation of beta-catenin at Ser45 by CK1 alpha";Reactome:R-HSA-198270 "PDPK1 phosphorylates AKT at T308";Reactome:R-HSA-198347 "AKT phosphorylates BAD";Reactome:R-HSA-198371 "AKT phosphorylates GSK3";Reactome:R-HSA-198599 "AKT phosphorylates MDM2";Reactome:R-HSA-198609 "AKT phosphorylates TSC2, inhibiting it";Reactome:R-HSA-198611 "AKT phosphorylates IKKalpha";Reactome:R-HSA-198613 "AKT phosphorylates p21Cip1 and p27Kip1";Reactome:R-HSA-198621 "AKT phosphorylates caspase-9";Reactome:R-HSA-198640 "TORC2 (mTOR) phosphorylates AKT at S473";Reactome:R-HSA-198669 "p38MAPK phosphorylates MSK1";Reactome:R-HSA-198731 "ERK1/2 activates ELK1";Reactome:R-HSA-198746 "ERK1/2/5 activate RSK1/2/3";Reactome:R-HSA-198756 "ERK1/2 phosphorylates MSK1";Reactome:R-HSA-199298 "AKT phosphorylates CREB1";Reactome:R-HSA-199299 "AKT phosphorylates FOXO transcription factors";Reactome:R-HSA-199839 "AKT can phosphorylate RSK";Reactome:R-HSA-199863 "AKT can phosphorylate NR4A1 (NUR77)";Reactome:R-HSA-199895 "RSK1/2/3 phosphorylates CREB at Serine 119";Reactome:R-HSA-199910 "MSK1 activates ATF1";Reactome:R-HSA-199917 "MAPKAPK2 phosphorylates CREB at Serine 133";Reactome:R-HSA-199929 "ERK5 activates the transcription factor MEF2";Reactome:R-HSA-199935 "MSK1 activates CREB";Reactome:R-HSA-200143 "AKT phosphorylates AKT1S1 (PRAS40)";Reactome:R-HSA-200421 "Activation of cytosolic AMPK by phosphorylation";Reactome:R-HSA-201677 "Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta";Reactome:R-HSA-201691 "Phosphorylation of LRP5/6 cytoplasmic domain by CSNKI";Reactome:R-HSA-201717 "CSNK2-mediated phosphorylation of DVL";Reactome:R-HSA-202111 "AKT1 phosphorylates eNOS";Reactome:R-HSA-202222 "Phosphorylation of PKC theta";Reactome:R-HSA-202437 "Phosphorylation of CARMA1";Reactome:R-HSA-202459 "Phosphorylation of Bcl10";Reactome:R-HSA-202500 "Activation of IKK complex";Reactome:R-HSA-202510 "Activation of TAK1-TAB2 complex";Reactome:R-HSA-202541 "p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB";Reactome:R-HSA-2028284 "Phosphorylation of STK4 (MST1) and SAV1 by STK4";Reactome:R-HSA-2028555 "Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1)";Reactome:R-HSA-2028583 "Phosphorylation of YAP by LATS2";Reactome:R-HSA-2028589 "Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2)";Reactome:R-HSA-2028591 "Phosphorylation of STK3 (MST2) and SAV1 by STK3";Reactome:R-HSA-2028598 "Phosphorylation of YAP by LATS1";Reactome:R-HSA-2028629 "Phosphorylation of MOB1A and B by p-STK4 (p-MST1)";Reactome:R-HSA-2028635 "Phosphorylation of MOB1A and B by p-STK3 (p-MST2)";Reactome:R-HSA-2028661 "Phosphorylation of WWTR1 (TAZ) by LATS2";Reactome:R-HSA-2028670 "Phosphorylation of MOB1A and B by p-STK4(MST1)/N";Reactome:R-HSA-2028673 "Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N";Reactome:R-HSA-2028675 "Phosphorylation of MOB1A and B by p-STK3(MST2)/N";Reactome:R-HSA-2028679 "Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N";Reactome:R-HSA-2029454 "Autophosphorylation of PAK1";Reactome:R-HSA-2029460 "PAK1 phosphorylates LIMK1";Reactome:R-HSA-2029469 "p-ERK phosphorylates WAVEs and ABI";Reactome:R-HSA-2060328 "Phosphorylation of WWTR1 (TAZ) by LATS1";Reactome:R-HSA-209087 "IKBA is phosphorylated by Phospho IKKB kinase";Reactome:R-HSA-211164 "AKT phosphorylates FOXO1A";Reactome:R-HSA-211583 "Partial autophosphorylation of PAK-2 at  Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197";Reactome:R-HSA-211650 "Autophosphorylation of PAK-2p34 in the activation loop";Reactome:R-HSA-2168079 "MASTL (GWL) phosphorylates ARPP19";Reactome:R-HSA-2176475 "Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9";Reactome:R-HSA-2214351 "PLK1 phosphorylates GORASP1";Reactome:R-HSA-2243938 "AKT1 E17K mutant is phosphorylated by TORC2 complex";Reactome:R-HSA-2243942 "PDPK1 phosphorylates AKT1 E17K mutant";Reactome:R-HSA-2294580 "PLK1 hyperphosphorylates Condensin II complex";Reactome:R-HSA-2396007 "IRF3 is phosphorylated by TBK1";Reactome:R-HSA-2399941 "AKT1 E17K mutant phosphorylates BAD";Reactome:R-HSA-2399966 "AKT1 E17K mutant phosphorylates GSK3";Reactome:R-HSA-2399969 "AKT1 E17K mutant phosphorylates p21Cip1 and p27Kip1";Reactome:R-HSA-2399977 "AKT1 E17K mutant phosphorylates AKT1S1 (PRAS40)";Reactome:R-HSA-2399981 "AKT1 E17K mutant phosphorylates MDM2";Reactome:R-HSA-2399982 "AKT1 E17K mutant phosphorylates TSC2, inhibiting it";Reactome:R-HSA-2399985 "AKT1 E17K mutant phosphorylates caspase-9";Reactome:R-HSA-2399988 "AKT1 E17K mutant phosphorylates NR4A1 (NUR77)";Reactome:R-HSA-2399992 "AKT1 E17K mutant phosphorylates forkhead box transcription factors";Reactome:R-HSA-2399996 "AKT1 E17K mutant phosphorylates CREB1";Reactome:R-HSA-2399999 "AKT1 E17K mutant phosphorylates RSK";Reactome:R-HSA-2400001 "AKT1 E17K mutant phosphorylates CHUK (IKKalpha)";Reactome:R-HSA-2422927 "MAPK3-3 or MAPK1 phosphorylate GORASP2";Reactome:R-HSA-2430535 "MASTL phosphorylates ENSA";Reactome:R-HSA-2466068 "Phosphorylation of cohesin by PLK1 at chromosomal arms";Reactome:R-HSA-2470508 "ACVR2A,B (ActRIIA,B) phosphorylates ACVR1C (ActRIC, ALK7) in response to Activin";Reactome:R-HSA-2529020 "CK2 phosphorylates condensin I subunits";Reactome:R-HSA-2562526 "PLK1 phosphorylates OPTN";Reactome:R-HSA-2574840 "AJUBA facilitates AURKA autophosphorylation";Reactome:R-HSA-2730856 "Autophosphorylation of PAK";Reactome:R-HSA-2730868 "Phosphorylation of MEK7 by MEKK1";Reactome:R-HSA-2730876 "Phosphorylation of IKK-beta by TAK1";Reactome:R-HSA-2730896 "Phosphorylation of MEK4 by MEKK1";Reactome:R-HSA-2730900 "Activation of TAK1 complex bound to pUb-TRAF6";Reactome:R-HSA-2984226 "PLK1 phosphorylates NEK9";Reactome:R-HSA-2984258 "NEK9 phosphorylates NEK6/NEK7";Reactome:R-HSA-2990880 "NEK6/NEK7 phosphorylates NUP98";Reactome:R-HSA-2993898 "VRK1/VRK2 phosphorylate BANF1";Reactome:R-HSA-3000310 "AURKA phosphorylates PLK1";Reactome:R-HSA-3000327 "PLK1 phosphorylates BORA";Reactome:R-HSA-3132737 "MAPKs phosphorylate ETS1 and ETS2";Reactome:R-HSA-3209160 "Activated ERKs phosphorylate ERF";Reactome:R-HSA-3222006 "STK11 (LKB1) phosphorylates NUAK1";Reactome:R-HSA-3222020 "NUAK1 phosphorylates TP53";Reactome:R-HSA-3228469 "MAP3K5 phosphorylates MKK3 and MKK6";Reactome:R-HSA-3229102 "p-MAPKAPK3 phosphorylates BMI1";Reactome:R-HSA-3229152 "MAP3K5 (ASK1) phosphorylates MAP2K4 (SEK1)";Reactome:R-HSA-3239014 "MAPKAPK5 phosphorylates TP53";Reactome:R-HSA-3239019 "Active p38 MAPK phosphorylates MAPKAPK5";Reactome:R-HSA-3249371 "TBK1 phosphorylates STAT6 at Ser407";Reactome:R-HSA-3371435 "Constitutive phosphorylation by GSK3";Reactome:R-HSA-3371531 "Constitutive phosphorylation  by pERK1/2";Reactome:R-HSA-3371567 "DBC1 is phosphorylated by ATM/ART";Reactome:R-HSA-349426 "Phosphorylation of MDM4 by CHEK2";Reactome:R-HSA-349444 "Phosphorylation of COP1 at Ser-387  by ATM";Reactome:R-HSA-349455 "Phosphorylation of MDM4 by ATM";Reactome:R-HSA-374696 "Phosphorylation of L1 by p90rsk";Reactome:R-HSA-3769394 "AKT phosphorylates CBY1";Reactome:R-HSA-377186 "Activated Akt1 phosphorylates AKT1S1 (PRAS40)";Reactome:R-HSA-3772435 "WNT signaling stimulates CSNK1-dependent phosphorylation of DVL";Reactome:R-HSA-380272 "Plk1-mediated phosphorylation of Nlp";Reactome:R-HSA-381091 "IRE1 dimer autophosphorylates";Reactome:R-HSA-381111 "EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK";Reactome:R-HSA-3857328 "RPS6KA1/2/3 phosphorylates CEBPB on S321";Reactome:R-HSA-3857329 "MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB";Reactome:R-HSA-3858480 "WNT-dependent phosphorylation of DVL";Reactome:R-HSA-389756 "AKT interacts and phosphorylates Cot";Reactome:R-HSA-392752 "Phosphorylation of L1 by CK-II";Reactome:R-HSA-3928577 "ROCK phosphorylates LIMK1,2";Reactome:R-HSA-3928608 "LIMK phosphorylates CFL1, inactivating it";Reactome:R-HSA-3928616 "Activated ROCK phosphorylates MRLCs";Reactome:R-HSA-3928620 "PAK1 autophosphorylates";Reactome:R-HSA-3928625 "PAKs autophosphorylate";Reactome:R-HSA-3928640 "PAKs phosphorylate MLC";Reactome:R-HSA-399939 "Autophosphorylation of PAK";Reactome:R-HSA-399944 "Phosphorylation of CRMPs by Cdk5";Reactome:R-HSA-399950 "Phosphorylation of cofilin by LIMK-1";Reactome:R-HSA-399951 "Phosphorylation of CRMPs by GSK3beta";Reactome:R-HSA-399952 "Phosphorylation of LIMK-1 by PAK";Reactome:R-HSA-399978 "Protein kinase C, alpha type phosphorylates MARCKS";Reactome:R-HSA-400382 "CSNK1E,CSNK1D phosphorylate CRY and PER proteins";Reactome:R-HSA-4088134 "PLK1 phosphorylates FOXM1";Reactome:R-HSA-419083 "Myosin phosphatase inactivation by ROCK";Reactome:R-HSA-419087 "LIM kinase phosphorylation by ROCK";Reactome:R-HSA-419197 "Myosin regulatory light chain phosphorylation by ROCK";Reactome:R-HSA-419644 "Transphosphorylation of pLIMK1";Reactome:R-HSA-428961 "Phosphorylation of cPLA2 by MAPK p38 alpha";Reactome:R-HSA-429016 "ALOX5 is phosphorylated by MAPKAP2";Reactome:R-HSA-429714 "CSNK1G2 phosphorylates p-CERT1-2";Reactome:R-HSA-432110 "Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding";Reactome:R-HSA-4332358 "Dissociation of CaM and CAMK2 autophosphorylation";Reactome:R-HSA-4332363 "Autophosphorylation and activation of CAMK2";Reactome:R-HSA-4332388 "Activation of MAP3K7 in response to WNT";Reactome:R-HSA-4411383 "NLK phosphorylates TCF/LEF";Reactome:R-HSA-4411402 "Activation of NLK";Reactome:R-HSA-442724 "Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs)";Reactome:R-HSA-442739 "PDPK1 phosphorylates RSKs";Reactome:R-HSA-442832 "PAK phosphorylates cortactin";Reactome:R-HSA-445072 "Interaction of PAK1 with Rac1-GTP";Reactome:R-HSA-446694 "IRAK4 phosphorylates IRAK1";Reactome:R-HSA-446701 "IRAK4-activated IRAK1 autophosphorylates";Reactome:R-HSA-448948 "Phosphorylation of E proteins by p38 MAPK";Reactome:R-HSA-448955 "Phosphorylation of MEF2 proteins by p38";Reactome:R-HSA-450222 "Active p38 MAPK phosphorylates MAPKAPK2 or 3";Reactome:R-HSA-450325 "c-FOS activation by phospho ERK1/2";Reactome:R-HSA-450337 "Activated TAK1 phosphorylates MKK4/MKK7";Reactome:R-HSA-450346 "activated human TAK1 phosphorylates MKK3/MKK6";Reactome:R-HSA-450463 "MK2 phosphorylates ZFP36 (Tristetraproline, TTP)";Reactome:R-HSA-450474 "MK2 phosphorylates BRF1";Reactome:R-HSA-450490 "Protein Kinase B/Akt phosphorylates BRF1";Reactome:R-HSA-450499 "Protein Kinase B (AKT) phosphorylates KSRP";Reactome:R-HSA-450827 "hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2";Reactome:R-HSA-451152 "MAP kinase p38 phosphorylates KSRP";Reactome:R-HSA-4551570 "VANGL2 is phosphorylated in response to WNT5A";Reactome:R-HSA-4608825 "DVL2 is phosphorylated after WNT5A binding to FZD";Reactome:R-HSA-4793911 "MAPKAPK2 phosphorylates HSF1";Reactome:R-HSA-5082387 "Phosphorylation of HSF1 at Ser230 induces transactivation";Reactome:R-HSA-5082405 "Phosphorylation of HSF1 at Ser326 induces transactivation";Reactome:R-HSA-5213464 "RIPK1 is phosphorylated";Reactome:R-HSA-5213466 "RIPK3 is phosphorylated";Reactome:R-HSA-5218814 "PAK2 autophorylates";Reactome:R-HSA-5218821 "PDK1 phosphorylates PKC";Reactome:R-HSA-5218826 "Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732";Reactome:R-HSA-5218854 "p-Y420-FYN is phosphorylated on S21";Reactome:R-HSA-5218906 "RIPK3 phosphorylates MLKL";Reactome:R-HSA-5218916 "p-MAPK2/3 phosphorylates HSP27";Reactome:R-HSA-5228811 "NFKBIA variant is not phosphorylated within IkBA:NF-kappaB";Reactome:R-HSA-5229343 "AXIN is phosphorylated in the destruction complex";Reactome:R-HSA-5260201 "p-AKT2 phosphorylates C2CD5";Reactome:R-HSA-5357472 "PAK1-3 autophosphorylates";Reactome:R-HSA-5357477 "PAK1-3 phosphorylates VE-cadherin";Reactome:R-HSA-5357831 "CHUK, IKBKB phosphorylate CYLD at S418";Reactome:R-HSA-5578777 "DMPK phosphorylates PLN";Reactome:R-HSA-5607722 "Active NIK phosphorylates IKKA dimer";Reactome:R-HSA-5607726 "Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB";Reactome:R-HSA-5607732 "K63polyUb-TAK1 autophosphorylates";Reactome:R-HSA-5607742 "K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta";Reactome:R-HSA-5610718 "CK1 phosphorylates p-GLI2";Reactome:R-HSA-5610722 "CK1 phosphorylates p-GLI3";Reactome:R-HSA-5610730 "GSK3 phosphorylates p-GLI2";Reactome:R-HSA-5610732 "GSK3 phosphorylates p-GLI3";Reactome:R-HSA-5624473 "Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit";Reactome:R-HSA-5624492 "PAK phosphorylates p21 RAF1 on S338";Reactome:R-HSA-5627775 "Autophosphorylation of PAK1,2,3";Reactome:R-HSA-5632670 "CSNK1A1 phosphorylates SMO dimer";Reactome:R-HSA-5632672 "ADRBK1 phosphorylates SMO dimer";Reactome:R-HSA-5635841 "GLI proteins are phosphorylated";Reactome:R-HSA-5635842 "ULK3 phosphorylates GLI";Reactome:R-HSA-5665868 "AMPK (complex) phosphorylates ULK1 (complex)";Reactome:R-HSA-5666160 "AURKB phosphorylates DIAPH2-2 at kinetochores";Reactome:R-HSA-5668545 "NIK autophosphorylates on T559";Reactome:R-HSA-5668932 "PAK2 phosphorylates myosin regulatory light chain (MRLC)";Reactome:R-HSA-5668947 "PAK1 phosphorylates myosin phosphatase";Reactome:R-HSA-5668984 "PAK1 or PAK2 phosphorylates MYLK";Reactome:R-HSA-5669250 "PAK1 phosphorylates FLNA";Reactome:R-HSA-5671763 "p-T774-PKN1 phosphorylates PPP1R14A";Reactome:R-HSA-5671919 "Activated CIT phosphorylates MRLCs";Reactome:R-HSA-5672008 "Thr-180 of ULK1 is phosphorylated";Reactome:R-HSA-5672010 "Active MTORC1 phosphorylates ULK1";Reactome:R-HSA-5672828 "mTORC1 phosphorylates AKT1S1";Reactome:R-HSA-5672948 "MARK3 phosphorylates KSR1";Reactome:R-HSA-5672973 "MAP2Ks phosphorylate MAPKs";Reactome:R-HSA-5672978 "RAF phosphorylates MAP2K dimer";Reactome:R-HSA-5674496 "Activated MAPKs phosphorylate MAP2K1";Reactome:R-HSA-5675194 "Activated MAPK phosphorylates RAF1";Reactome:R-HSA-5675198 "Activated MAPKs phosphorylate BRAF";Reactome:R-HSA-5675868 "ULK1 phosphorylates ATG13 and RB1CC1";Reactome:R-HSA-5679205 "ULK1 phosphorylates Beclin-1";Reactome:R-HSA-5682026 "MRN bound to shortened telomeres activates ATM";Reactome:R-HSA-5682101 "PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer";Reactome:R-HSA-5682598 "ATM phosphorylates HERC2";Reactome:R-HSA-5682983 "ATM phosphorylates WHSC1";Reactome:R-HSA-5683425 "ATM phosphorylates TP53BP1 at DNA DSBs";Reactome:R-HSA-5683792 "p-T68-CHEK2 autophosphorylates";Reactome:R-HSA-5683801 "CHEK2 phosphorylates BRCA1";Reactome:R-HSA-5683964 "ATM phosphorylates EYA1-4";Reactome:R-HSA-5684096 "CDK2 phosphorylates RBBP8";Reactome:R-HSA-5684140 "ATM phosphorylates RBBP8";Reactome:R-HSA-5684887 "Activation of CHEK1 at resected DNA DSBs";Reactome:R-HSA-5685156 "ATR phosphorylates RPA2";Reactome:R-HSA-5685230 "CHEK1 phosphorylates RAD51";Reactome:R-HSA-5685242 "CHEK1 phosphorylates BRCA2";Reactome:R-HSA-5686578 "Activated ATM phosphorylates ABL1";Reactome:R-HSA-5686704 "Activated ATM phosphorylates DCLRE1C";Reactome:R-HSA-5687086 "PAK1,2,3 phosphorylates MAPK6,4";Reactome:R-HSA-5687090 "p-S MAPK6 phosphorylates NCOA3";Reactome:R-HSA-5687094 "p-S MAPK6,4 phosphorylate MAPKAPK5";Reactome:R-HSA-5687101 "p-T182 MAPKAPK5 phosphorylates FOXO3";Reactome:R-HSA-5687121 "p-S MAPKAPK5 phosphorylates HSPB1";Reactome:R-HSA-5687183 "PRKDC phosphorylates DCLRE1C at DNA DSBs";Reactome:R-HSA-5690250 "p-T182-MAPKAPK5 phoshphorylates DNAJB1";Reactome:R-HSA-5692768 "MAPKAPK5 phosphorylates KALRN";Reactome:R-HSA-5692775 "SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs";Reactome:R-HSA-5692779 "p-T182 MAPKAPK5 phosphorylates FOXO1";Reactome:R-HSA-5693536 "ATM phosphorylates MDC1";Reactome:R-HSA-5693540 "MRN activates ATM";Reactome:R-HSA-5693549 "ATM phosphorylates histone H2AFX on S139 at DNA DSBs";Reactome:R-HSA-5693551 "Phosphorylation of BRCA1-A complex at multiple sites by ATM";Reactome:R-HSA-5693575 "DNA-PKcs autophosphorylates";Reactome:R-HSA-5693598 "ATM phosphorylates NBN";Reactome:R-HSA-5693609 "ATM phosphorylates TP53 at S15";Reactome:R-HSA-5694441 "CSNK1D phosphorylates SEC23";Reactome:R-HSA-6788392 "ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA";Reactome:R-HSA-6795290 "TORC2 complex phosphorylates SGK1";Reactome:R-HSA-6795460 "SGK1 phosphorylates MDM2";Reactome:R-HSA-6795473 "PDPK1 phosphorylates SGK1";Reactome:R-HSA-6798372 "ATM phosphorylates DYRK2";Reactome:R-HSA-6798374 "DYRK2 phosphorylates TP53";Reactome:R-HSA-6799097 "ATM phosphorylates ZNF420";Reactome:R-HSA-6799246 "CHEK1 phosphorylates TP53";Reactome:R-HSA-6799332 "ATR phosphorylates TP53";Reactome:R-HSA-6799409 "HIPK2 phosphorylates TP53";Reactome:R-HSA-6800490 "ATM phosphorylates PIDD1";Reactome:R-HSA-6801666 "PLK2 phosphorylates CENPJ";Reactome:R-HSA-6801675 "PLK2 phosphorylates NPM1";Reactome:R-HSA-6802911 "High kinase activity BRAF complexes phosphorylate MAP2Ks";Reactome:R-HSA-6802919 "RAS:GTP:moderate kinase activity p-RAF complexes phosphorylate MAP2Ks";Reactome:R-HSA-6802926 "Mutant RAS:p-RAF complexes phosphorylate MAP2Ks";Reactome:R-HSA-6802933 "p-BRAF and RAF fusion dimers phosphorylate MAP2Ks";Reactome:R-HSA-6802935 "MAPKs are phosphorylated downstream of BRAF and RAF fusion dimers";Reactome:R-HSA-6802943 "RAS:GTP:inactive p-RAF complexes phosphorylate MAP2Ks";Reactome:R-HSA-6802973 "PLK3 phosphorylates CDC25C";Reactome:R-HSA-6804266 "CHEK2 phosphorylates TTC5";Reactome:R-HSA-6804276 "ATM phosphorylates TTC5";Reactome:R-HSA-6804955 "ATM phosphorylates MDM2";Reactome:R-HSA-6805059 "CK2:FACT phosphorylates TP53";Reactome:R-HSA-6805103 "AURKA phosphorylates TP53";Reactome:R-HSA-6805126 "AURKB phosphorylates TP53";Reactome:R-HSA-6805276 "CDK5 phosphorylates TP53";Reactome:R-HSA-6805285 "PLK3 phosphorylates TP53";Reactome:R-HSA-6805399 "TAF1 phosphorylates TP53";Reactome:R-HSA-6805479 "TP53RK phosphorylates TP53";Reactome:R-HSA-6805640 "AKT phosphorylates KAT6A";Reactome:R-HSA-6805785 "AKT phosphorylates PHF20";Reactome:R-HSA-6810233 "CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter";Reactome:R-HSA-6811454 "MAPKs phosphorylate PP2A";Reactome:R-HSA-6814409 "CK2 phosphorylates PDCL";Reactome:R-HSA-69604 "Phosphorylation of Cdc25A at Ser-123 by Chk1";Reactome:R-HSA-69608 "Phosphorylation of Cdc25A at Ser-123 by Chk2";Reactome:R-HSA-69685 "CHEK2 phosphorylates TP53";Reactome:R-HSA-69891 "Phosphorylation and activation of CHEK2 by ATM";Reactome:R-HSA-75010 "Phosphorylation of Cdc25C at Ser 216 by Chk1";Reactome:R-HSA-75028 "Phosphorylation of Wee1 kinase by Chk1";Reactome:R-HSA-75809 "Phosphorylation of Cdc25C at Ser216 by CHEK2";Reactome:R-HSA-75820 "Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta";Reactome:R-HSA-77071 "Phosphorylation (Ser5) of RNA pol II CTD";Reactome:R-HSA-8850945 "Casein kinase II phosphorylates PTEN";Reactome:R-HSA-8852306 "Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends";Reactome:R-HSA-8852317 "PLK1 phosphorylates GTSE1";Reactome:R-HSA-8853419 "TPX2 promotes AURKA autophosphorylation";Reactome:R-HSA-8853444 "AURKA phosphorylates PHLDA1";Reactome:R-HSA-8854908 "PKA phosphorylates RET:GDNF:GFRA dimer";Reactome:R-HSA-8856813 "AAK1 phosphorylates AP-2 mu subunit at T156";Reactome:R-HSA-8863007 "p25-bound CDK5 phosphorylates CDC25B";Reactome:R-HSA-8863011 "p25-bound CDK5 phosphorylates CDC25C";Reactome:R-HSA-8863014 "p25-bound CDK5 phosphorylates CDC25A";Reactome:R-HSA-8863895 "IKKB phosphorylates SNAP23";Reactome:R-HSA-8868118 "MAPK12 phosphorylates PTPN3";Reactome:R-HSA-8868260 "CDK5:p25 phosphorylates GOLGA2";Reactome:R-HSA-8868340 "CDK5:p25 phosphorylates lamin B1";Reactome:R-HSA-8868344 "CDK5:p25 phosphorylates lamin A";Reactome:R-HSA-8868567 "CDK5:p25 phosphorylates PRDX1";Reactome:R-HSA-8868573 "CDK5:p25 phosphorylates PRDX2";Reactome:R-HSA-8868666 "CDK5:p25 phosphorylates JUN";Reactome:R-HSA-8870558 "CDK5:p25 phosphorylates FOXO3";Reactome:R-HSA-8873929 "Casein kinase II phosphorylates STARD10";Reactome:R-HSA-8876446 "p-ULK1 phosphorylates DENND3";Reactome:R-HSA-8877691 "MAP2K6 phosphorylates PIP4K2B";Reactome:R-HSA-8878050 "HIPK2 phosphorylates RUNX1 and EP300";Reactome:R-HSA-8878054 "HIPK2 phosphorylates RUNX1";Reactome:R-HSA-8932322 "CK2 phosphorylates NFE2L2";Reactome:R-HSA-8933446 "Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling";Reactome:R-HSA-8939963 "Activated AKT phosphorylates RUNX2";Reactome:R-HSA-8940100 "CDK1 phosphorylates VCPIP1";Reactome:R-HSA-8942836 "CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6";Reactome:R-HSA-8944454 "mTORC1 phosphorylates MAF1";Reactome:R-HSA-8948039 "FUNDC1 is phosphorylated by CK2";Reactome:R-HSA-8948146 "FUNDC1 is phosphorylated by ULK1 at Ser17";Reactome:R-HSA-8948757 "AKT phosphorylates MKRN1";Reactome:R-HSA-8952289 "FAM20C phosphorylates FAM20C substrates";Reactome:R-HSA-9007539 "CHEK1 phosphorylates E2F6";Reactome:R-HSA-9008480 "GSK3B phosphorylates RUNX2";Reactome:R-HSA-9008822 "PPM1D dephosphorylates RUNX2";Reactome:R-HSA-9009208 "Activated ERKs phosphorylate RUNX2";Reactome:R-HSA-9012319 "p-TEFb phosphorylates serine 2 in RNA polymerase II CTD";Reactome:R-HSA-9013978 "Phosphorylation of IRF-3/IRF7 and their release from the activated TLR3 complex";Reactome:R-HSA-9022314 "HIPK2 phosphorylates MECP2";Reactome:R-HSA-9023132 "AURKB phosphorylates MECP2 at S423";Reactome:R-HSA-9032751 "Estrogen-independent phosphorylation of ESR1 S118 by MAPK1 and MAPK3";Reactome:R-HSA-9032863 "CDK5 phosphorylates NTRK2";Reactome:R-HSA-912470 "ATR phosphorylates Histone H2A.X at unsynapsed regions";Reactome:R-HSA-913996 "PKA/PKG phosphorylate Rap1GAP2";Reactome:R-HSA-918229 "Phosphorylation and release of IRF3/IRF7";Reactome:R-HSA-933525 "Phosphorylation and release of IRF7";Reactome:R-HSA-934559 "SPRY2 is phosphorylated by phosphorylated MNK1";Reactome:R-HSA-936951 "Activation of TAK1 complex bound to activated TLR4 complex";Reactome:R-HSA-937022 "IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP";Reactome:R-HSA-937059 "Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex";Reactome:R-HSA-9604328 "AKT1 phosphorylates NOTCH4";Reactome:R-HSA-9610153 "Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF";Reactome:R-HSA-9610156 "MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF";Reactome:R-HSA-9610163 "BRAF autophosphorylates downstream of RAP1 and NGF";Reactome:R-HSA-9612501 "SGK phosphorylates CREB1";Reactome:R-HSA-9612509 "SGK phosphorylates SRF";Reactome:R-HSA-9612980 "BRAF in Rap1-GTP complex:BRAF complex autophosphorylates";Reactome:R-HSA-9613530 "PRKAA2 phosphorylates PLINs";Reactome:R-HSA-9619515 "AMPK phosphorylates MAPT";Reactome:R-HSA-9619843 "ERKs phosphorylate RSKs";Reactome:R-HSA-9620004 "RSKs autophosphorylate";Reactome:R-HSA-9624526 "AKT phosphorylates FOXO3 downstream of ESR1 and EGFR";Reactome:R-HSA-9626880 "MAPK11 or MAPK14 phosphorylates NCF1 at Ser345";Reactome:R-HSA-9627089 "CASP9 is phosphorylated at T412";Reactome:R-HSA-9632868 "CDKN1B is phosphorylated in response to estrogen";Reactome:R-HSA-9633008 "p-T899-EIF2AK4 (GCN2) phosphorylates EIF2AS1";Reactome:R-HSA-9633742 "EIF2AK4 (GCN2) dimer autophosphorylates";Reactome:R-HSA-9634702 "LINC01139 promotes phosphorylation of HIF1A by LRRK2";Reactome:R-HSA-9645535 "ALPK1 phosphorylates TIFA";Reactome:R-HSA-9648089 "NEK6 and NEK7 phosphorylate EML4";Reactome:R-HSA-9648883 "p-T-EIF2AK1:ferriheme dimer autophosphorylates";Reactome:R-HSA-9648888 "p-T,T486,T488-EIF2AK1 phosphorylates EIF2S1 (eIF2-alpha)";Reactome:R-HSA-9652165 "MAP2K mutants constitutively phosphorylate MAPKs";Reactome:R-HSA-9653503 "KRAS4B is phosphorylated on serine 181";Reactome:R-HSA-9656214 "MAP2Ks phosphorylate MAPKs downstream of RAF1 mutants";Reactome:R-HSA-9656215 "RAF1 mutant complexes phosphorylate MAP2K dimer";Reactome:R-HSA-9662823 "PLK2, MAPK14 phosphorylate ADAM17";Reactome:R-HSA-9673346 "Unknown kinase phosphorylates p-DVL";Reactome:R-HSA-9683664 "GSK3 phosphorylates Nucleoprotein";Reactome:R-HSA-9699579 "AKT phosphorylates FOXO3 downstream of FLT3";Reactome:R-HSA-9705320 "TBK1, IKBKE are autophosphorylated at Ser172";Reactome:R-HSA-9705323 "Phosphorylation of TBK1/IKBKE";Reactome:R-HSA-9725030 "MAPK1 phsophorylates ZC3HCF1 in a NPM-ALK-dependent manner";Reactome:R-HSA-9729260 "GSK3 phosphorylates nucleoprotein";Reactome:R-HSA-9729300 "Unknown kinase phosphorylates nucleoprotein";Reactome:R-HSA-9729318 "CSNK1A1 phosphorylates nucleoprotein";Reactome:R-HSA-9731111 "MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3";Reactome:R-HSA-9734547 "JAK2-activated MAPKs phosphorylate YBX1";Reactome:R-HSA-975125 "Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9";Reactome:R-HSA-975134 "Second phosphorylation of IRAK1 by IRAK4 bound to MyD88;Reactome:R-HSA-975160 "Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:activated TLR 7/8 or 9";Reactome:R-HSA-975170 "IRAK4 autophosphorylation in the complex with MyD88:activated TLR 7/8 or 9";Reactome:R-HSA-975180 "First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9";Reactome:R-HSA-9758486 "Unknown kinase phosphorylates 9b";Reactome:R-HSA-975853 "Multiple IRAK1 autophosphorylation within the complex p-IRAK4:oligo MyD88:activated TLR";Reactome:R-HSA-975861 "Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomerl:activated TLR5 or 10 complex";Reactome:R-HSA-975865 "IRAK4 autophosphorylation within the complex activated TLR:MyD88";Reactome:R-HSA-975874 "Second phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR complex";Reactome:R-HSA-975878 "First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR";Reactome:R-HSA-9762094 "GSK3B phosphorylates p-NFE2L2";Reactome:R-HSA-9766532 "SQSTM1 oligomer is phosphorylated";Reactome:R-HSA-9769115 "MAPK1,(MAPK3) phosphorylates NPAS4";Reactome:R-HSA-9773803 "Active IKBKB phosphorylates NF-kappa-B inhibitor";Reactome:R-HSA-9796067 "PRKAA2 phosphorylates nuclear NFE2L2";Reactome:R-HSA-9796081 "EIF2AK3 phosphorylates NFE2L2";Reactome:R-HSA-9815501 "MAPKAPK2 phosphorylates RIPK1 at S320";Reactome:R-HSA-9817397 "TBK1, IKBKE phosphorylate RIPK1 at T189";Reactome:R-HSA-9818789 "CHUK, IKBKB phosphorylate RIPK1 at S25";Reactome:R-HSA-9819106 "ULK1 phosphorylates RIPK1 at S357";Reactome:R-HSA-9824582 "MAPK1 phosphorylates SOX10";Reactome:R-HSA-9824897 "p-S-TBK1 phosphorylates OPTN";Reactome:R-HSA-9824977 "MAPK1-dependent phosphorylation of MITF-M";Reactome:R-HSA-9824994 "RPS6KA1-dependent phosphorylation of MITF-M";Reactome:R-HSA-9824995 "GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405";Reactome:R-HSA-9824999 "GSK3B phosphorylates p-S73 MITF-M at residue S69";Reactome:R-HSA-9825704 "AKT3 phosphorylates TBX3";Reactome:R-HSA-9831514 "CK2 phosphorylates nascent P";Reactome:R-HSA-9831712 "M dimer is phosphorylated";Reactome:R-HSA-9832782 "p-S232-S237-P is further phosphorylated";Reactome:R-HSA-9834076 "PINK1 is autophosphorylated";Reactome:R-HSA-9834945 "PINK1 phosphorylates Ub on MOM proteins";Reactome:R-HSA-9835011 "PINK1 phosphorylates PRKN at S65";Reactome:R-HSA-9839363 "TGFBR3 phosphorylation by TGFBR2 complex";Reactome:R-HSA-9851972 "PLK1 phosphorylates FIRRM at S43";Reactome:R-HSA-9853369 "PLK1 phosphorylates FIRMM at S744";Reactome:R-HSA-9855910 "USF1 is phosphorylated by p-MAPK14";Reactome:R-HSA-9860292 "Activated IKBKB phosphorylates IRF5";Reactome:R-HSA-9860785 "PDPK1 (PDK1) phosphorylates PKN2 on threonine-816";Reactome:R-HSA-9860800 "mTORC2 phosphorylates AKT1 on serine-473";Reactome:R-HSA-9861642 "NEK1 phosphorylates ME1"
molecular_function	GO:0008396	oxysterol 7-alpha-hydroxylase activity
	xrefs	Reactome:R-HSA-191972 "27-hydroxycholesterol is 7alpha-hydroxylated";Reactome:R-HSA-192065 "CYP7B1 7-hydroxylates 25OH-CHOL";Reactome:R-HSA-192178 "CYP39A1 7-hydroxylates 24OH-CHOL";Reactome:R-HSA-5602885 "Defective CYP7B1 does not 7-hydroxylate 25OH-CHOL";RHEA:68740	WAS	Reactome:R-HSA-191972 "27-hydroxycholesterol is 7alpha-hydroxylated";Reactome:R-HSA-192065 "CYP7B1 7-hydroxylates 25OH-CHOL";Reactome:R-HSA-192178 "CYP39A1 7-hydroxylates 24OH-CHOL";Reactome:R-HSA-5602885 "Defective CYP7B1 does not 7-hydroxylate 25OH-CHOL"
molecular_function	GO:0008397	sterol 12-alpha-hydroxylase activity
	xrefs	EC:1.14.14.139;RHEA:46752	WAS	EC:1.14.14.139
molecular_function	GO:0008412	4-hydroxybenzoate polyprenyltransferase activity
	xrefs	EC:2.5.1.39;MetaCyc:RXN-11368;RHEA:44504	WAS	EC:2.5.1.39;MetaCyc:RXN-11368;Reactome:R-HSA-2162192 "COQ2 ligates all-E-10PrP2 to PHB";RHEA:44504
molecular_function	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase activity
	xrefs	Reactome:R-HSA-2076383 "HS3ST1 sulfates GlcN at C3 in heparan sulfate";Reactome:R-HSA-2076611 "HS3STs sulfate GlcN at C3 in heparan sulfate";RHEA:15461	WAS	EC:2.8.2.23;MetaCyc:2.8.2.23-RXN;Reactome:R-HSA-2076383 "HS3ST1 sulfates GlcN at C3 in heparan sulfate";Reactome:R-HSA-2076611 "HS3STs sulfate GlcN at C3 in heparan sulfate"
molecular_function	GO:0008695	3-phenylpropionate dioxygenase activity
	xrefs	EC:1.14.12.19;MetaCyc:HCAMULTI-RXN;RHEA:20357;UM-BBD_enzymeID:e0307	WAS	EC:1.14.12.19;MetaCyc:HCAMULTI-RXN;RHEA:20357;UM-BBD_enzymeID:r0434
molecular_function	GO:0008942	nitrite reductase [NAD(P)H] activity
	xrefs	EC:1.7.1.4;KEGG_REACTION:R00787;KEGG_REACTION:R00789;MetaCyc:RXN0-6377	WAS	EC:1.7.1.4;KEGG_REACTION:R00787;KEGG_REACTION:R00789;MetaCyc:RXN0-6377;RHEA:24632
molecular_function	GO:0010291	beta-carotene 3-hydroxylase activity
	xrefs	EC:1.14.15.24;MetaCyc:RXN1F-152;RHEA:30331	WAS	N/A
molecular_function	GO:0016303	1-phosphatidylinositol-3-kinase activity
	xrefs	EC:2.7.1.137;KEGG_REACTION:R03362;MetaCyc:1-PHOSPHATIDYLINOSITOL-3-KINASE-RXN;Reactome:R-HSA-109699 "PI3K-containing complexes phosphorylate PIP2 to PIP3";Reactome:R-HSA-1433514 "Synthesis of PIP3 from PIP2 by PI3K";Reactome:R-HSA-1675939 "PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane";Reactome:R-HSA-1675961 "PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane";Reactome:R-HSA-1676024 "PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane";Reactome:R-HSA-2045911 "BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3";Reactome:R-HSA-5672012 "Beclin-1 complex phosphorylates PtdIns";Reactome:R-HSA-6798174 "PIK3C3:PIK3R4 phosphorylates PI to PI3P";Reactome:R-HSA-9670433 "KIT mutants:PI3K catalyze synthesis of PIP3";Reactome:R-HSA-9680389 "CSF1R-associated phosphatidylinositol 3-kinase (PI3K) phosphorylates PI(4,5)P2";RHEA:12709	WAS	EC:2.7.1.137;KEGG_REACTION:R03362;MetaCyc:1-PHOSPHATIDYLINOSITOL-3-KINASE-RXN;Reactome:R-HSA-109699 "PI3K-containing complexes phosphorylate PIP2 to PIP3";Reactome:R-HSA-1433514 "Synthesis of PIP3 from PIP2 by PI3K";Reactome:R-HSA-1675939 "PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane";Reactome:R-HSA-1675961 "PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane";Reactome:R-HSA-1676024 "PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane";Reactome:R-HSA-2045911 "BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3";Reactome:R-HSA-5672012 "Beclin-1 complex phosphorylates PtdIns";Reactome:R-HSA-6798174 "PIK3C3:PIK3R4 phosphorylates PI to PI3P";Reactome:R-HSA-9670433 "KIT mutants:PI3K catalyze synthesis of PIP3";Reactome:R-HSA-9680389 "CSF1R-associated phosphatidylinositol 3-kinase (PI3K) phosphorylates PI(4,5)P2";RHEA:12709;Wikipedia:Phosphoinositide_3-kinase
molecular_function	GO:0017040	N-acylsphingosine amidohydrolase activity
	xrefs	EC:3.5.1.23;MetaCyc:CERAMIDASE-RXN;Reactome:R-HSA-1606583 "ASAH2 hydrolyzes ceramide (plasma membrane)";Reactome:R-HSA-1606602 "ASAH1 hydrolyzes ceramide";Reactome:R-HSA-428205 "ACER2 hydrolyzes ceramide (Golgi)";Reactome:R-HSA-428231 "ACER1 hydrolyzes ceramide (endoplasmic reticulum)";RHEA:20856	WAS	EC:3.5.1.23;MetaCyc:CERAMIDASE-RXN;Reactome:R-HSA-1606583 "ASAH2 hydrolyzes ceramide (plasma membrane)";Reactome:R-HSA-1606602 "ASAH1 hydrolyzes ceramide";Reactome:R-HSA-428205 "ACER2 hydrolyzes ceramide (Golgi)";Reactome:R-HSA-428231 "ACER1 hydrolyzes ceramide (endoplasmic reticulum)";Reactome:R-HSA-428262 "ACER3 hydrolyzes phytoceramide";RHEA:20856
molecular_function	GO:0017095	heparan sulfate 6-sulfotransferase activity
	xrefs	Reactome:R-HSA-2076419 "HS6STs sulfate GlcN at C6 in heparan sulfate/heparin";RHEA:56604	WAS	Reactome:R-HSA-2076419 "HS6STs sulfate GlcN at C6 in heparan sulfate/heparin"
molecular_function	GO:0018591	methyl tertiary butyl ether 3-monooxygenase activity
	xrefs	UM-BBD_reactionID:r1023	WAS	N/A
molecular_function	GO:0018594	tert-butanol 2-monooxygenase activity
	xrefs	UM-BBD_reactionID:r0615	WAS	N/A
molecular_function	GO:0018755	2-chloro-4-hydroxy-6-amino-1,3,5-triazine aminohydrolase activity
	xrefs	UM-BBD_reactionID:r1414	WAS	N/A
molecular_function	GO:0018812	3-hydroxyacyl-CoA dehydratase activity
	xrefs	EC:4.2.1.74;Reactome:R-HSA-2066778 "Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA";Reactome:R-HSA-2066780 "Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA";Reactome:R-HSA-389986 "trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA";Reactome:R-HSA-390252 "HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA";Reactome:R-HSA-5676637 "PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA";Reactome:R-HSA-6809263 "EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA";Reactome:R-HSA-8957389 "RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA";RHEA:33767	WAS	EC:4.2.1.74;MetaCyc:LONG-CHAIN-ENOYL-COA-HYDRATASE-RXN;Reactome:R-HSA-2066778 "Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA";Reactome:R-HSA-2066780 "Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA";Reactome:R-HSA-389986 "trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA";Reactome:R-HSA-390252 "HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA";Reactome:R-HSA-5676637 "PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA";Reactome:R-HSA-6809263 "EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA";Reactome:R-HSA-8957389 "RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA";RHEA:33767
molecular_function	GO:0019833	ice nucleation activity
	xrefs	TC:9.B.133.1.1	WAS	N/A
molecular_function	GO:0035241	protein-arginine omega-N monomethyltransferase activity
	xrefs	EC:2.1.1.321;RHEA:48100	WAS	EC:2.1.1.321;MetaCyc:2.1.1.124-RXN;RHEA:48100
molecular_function	GO:0035244	protein-arginine C-methyltransferase activity
	xrefs	EC:2.1.1.379;RHEA:66028	WAS	EC:2.1.1.379;RESID:AA0272;RHEA:66028
molecular_function	GO:0036185	13-lipoxin reductase activity
	xrefs	Reactome:R-HSA-2161844 "15k-LXA4 is reduced to dhk-LXA4 by PTGR1";RHEA:41592	WAS	Reactome:R-HSA-2161844 "15k-LXA4 is reduced to dhk-LXA4 by PTGR1"
molecular_function	GO:0042768	ecdysteroid 2-hydroxylase activity
	xrefs	N/A	WAS	MetaCyc:RXN-14679
molecular_function	GO:0043786	cinnamate reductase activity
	xrefs	RHEA:50944	WAS	N/A
molecular_function	GO:0046905	15-cis-phytoene synthase activity
	xrefs	MetaCyc:RXN-13323;RHEA:34475	WAS	RHEA:34479
molecular_function	GO:0047403	lacto-N-biosidase activity
	xrefs	EC:3.2.1.140;MetaCyc:RXN-8731;RHEA:21568	WAS	EC:3.2.1.140;RHEA:21568
molecular_function	GO:0047792	cyanohydrin beta-glucosyltransferase activity
	xrefs	EC:2.4.1.85;MetaCyc:RXN-743;RHEA:12853	WAS	EC:2.4.1.85;RHEA:12853
molecular_function	GO:0050108	monoterpenyl-diphosphatase activity
	xrefs	MetaCyc:MONOTERPENYL-PYROPHOSPHATASE-RXN;RHEA:81371	WAS	MetaCyc:MONOTERPENYL-PYROPHOSPHATASE-RXN
molecular_function	GO:0051269	alpha-ketoester reductase (NADPH) activity
	xrefs	RHEA:80767	WAS	N/A
molecular_function	GO:0051996	squalene synthase [NAD(P)H] activity
	xrefs	EC:2.5.1.21;MetaCyc:RXN66-281	WAS	EC:2.5.1.21;MetaCyc:RXN66-281;Reactome:R-HSA-191402 "Reduction of presqualene diphosphate to form squalene";Reactome:R-HSA-191405 "Two FPP molecules dimerize to form presqualene diphosphate"
molecular_function	GO:0052849	curcumin reductase (NADP+) activity
	xrefs	MetaCyc:RXN0-6676;RHEA:34815	WAS	EC:1.3.1.n3;MetaCyc:RXN0-6676
molecular_function	GO:0052856	NAD(P)HX epimerase activity
	xrefs	EC:5.1.99.6	WAS	EC:5.1.99.6;Reactome:R-HSA-6806966 "APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX"
molecular_function	GO:0052903	N(1)-acetylpolyamine oxidase (3-acetamidopropanal-forming) activity
	xrefs	EC:1.5.3.13;KEGG_REACTION:R03899;MetaCyc:RXN-12090	WAS	EC:1.5.3.13;KEGG_REACTION:R03899;MetaCyc:RXN-12090;Reactome:R-HSA-141348 "PAO:FAD oxidises NASPM to PTCN";Reactome:R-HSA-141351 "PAOX:FAD oxidises NASPN to SPM"
molecular_function	GO:0055056	D-glucose transmembrane transporter activity
	xrefs	Reactome:R-HSA-429094 "SLC2A6,8,10,12 transport Glc from extracellular region to cytosol";Reactome:R-HSA-450095 "GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region";Reactome:R-HSA-5339524 "GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol";Reactome:R-HSA-5632804 "SLC2A1 tetramer does not transport Glc from extracellular region to cytosol";Reactome:R-HSA-5632871 "Defective SLC2A10 does not transport Glc from extracellular region to cytosol";Reactome:R-HSA-8981553 "GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol";Reactome:R-HSA-8981564 "GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol";Reactome:R-HSA-8981570 "GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol";Reactome:R-HSA-8981574 "GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol"	WAS	Reactome:R-HSA-429094 "SLC2A6,8,10,12 transport Glc from extracellular region to cytosol";Reactome:R-HSA-450095 "GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region";Reactome:R-HSA-499981 "Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2";Reactome:R-HSA-5339524 "GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol";Reactome:R-HSA-5632804 "SLC2A1 tetramer does not transport Glc from extracellular region to cytosol";Reactome:R-HSA-5632871 "Defective SLC2A10 does not transport Glc from extracellular region to cytosol";Reactome:R-HSA-5653873 "SLC2A1 tetramer transports Glc from cytosol to Golgi lumen";Reactome:R-HSA-8981553 "GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol";Reactome:R-HSA-8981564 "GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol";Reactome:R-HSA-8981570 "GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol";Reactome:R-HSA-8981574 "GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol"
molecular_function	GO:0062101	peptidyl-aspartic acid 3-dioxygenase activity
	xrefs	EC:1.14.11.16;MetaCyc:PEPTIDE-ASPARTATE-BETA-DIOXYGENASE-RXN;Reactome:R-HSA-9631355 "ASPH:Fe2+ hydroxylates an aspartate residue of F9";RHEA:11508	WAS	EC:1.14.11.16;MetaCyc:PEPTIDE-ASPARTATE-BETA-DIOXYGENASE-RXN;Reactome:R-HSA-9631355 "ASPH:Fe2+ hydroxylates an aspartate residue of F9";RESID:AA0026;RHEA:11508
molecular_function	GO:0070330	aromatase activity
	xrefs	EC:1.14.14.14	WAS	EC:1.14.14.14;UM-BBD_reactionID:r1132;UM-BBD_reactionID:r1137
molecular_function	GO:0090555	phosphatidylethanolamine flippase activity
	xrefs	N/A	WAS	RHEA:66132
molecular_function	GO:0099618	UDP-glucuronate dehydrogenase activity
	xrefs	EC:1.1.1.305;MetaCyc:RXN0-1861;RHEA:24702	WAS	EC:1.1.1.305;RHEA:24702
molecular_function	GO:0102140	heparan sulfate N-deacetylase activity
	xrefs	RHEA:70587	WAS	MetaCyc:RXN-11557
molecular_function	GO:0102175	3-beta-hydroxysteroid dehydrogenase (NAD+)/C4-decarboxylase activity
	xrefs	EC:1.1.1.418;MetaCyc:RXN-11928;RHEA:34775	WAS	MetaCyc:RXN-11928;RHEA:34775
molecular_function	GO:0102274	glutathione S-conjugate carboxypeptidase activity
	xrefs	EC:3.4.17.25;MetaCyc:RXN-12532;RHEA:60448	WAS	MetaCyc:RXN-12532
molecular_function	GO:0103031	L-Ala-D/L-Glu epimerase activity
	xrefs	EC:5.1.1.20;MetaCyc:RXN0-5228;RHEA:28394	WAS	MetaCyc:RXN0-5228;RHEA:28394
molecular_function	GO:0106359	2-hydroxyacyl-CoA lyase activity
	xrefs	EC:4.1.2.63	WAS	EC:4.1.2.63;MetaCyc:RXN66-471
molecular_function	GO:0106364	4-hydroxy-3-all-trans-polyprenylbenzoate oxygenase activity
	xrefs	N/A	WAS	MetaCyc:RXN3O-58;RHEA:20361
molecular_function	GO:0141207	peptide lactyltransferase (ATP-dependent) activity
	xrefs	RHEA:80271	WAS	N/A
molecular_function	GO:0141208	NAD-dependent protein lysine delactylase activity
	xrefs	RHEA:80287	WAS	N/A
molecular_function	GO:0141215	N-acetyltaurine hydrolase activity
	xrefs	RHEA:81107	WAS	N/A
molecular_function	GO:0160128	pH-gated monoatomic ion channel activity
	xrefs	Reactome:R-HSA-2671885 "ASIC trimers:H+ transport extracellular Na+ to cytosol"	WAS	Reactome:R-HSA-2671885 "ASIC trimers:H+ transport extracellular Na+ to cytosol";Wikipedia:Acid-sensing_ion_channel
molecular_function	GO:0160198	polyprenal reductase activity
	xrefs	EC:1.3.1.94;MetaCyc:RXN-9971;RHEA:80727	WAS	EC:1.3.1.94;MetaCyc:RXN-9971
molecular_function	GO:0160216	protein lysine delactylase activity
	xrefs	RHEA:81387	WAS	N/A
molecular_function	GO:1990055	phenylacetaldehyde synthase activity
	xrefs	EC:4.1.1.109;MetaCyc:RXN-8990;RHEA:55532	WAS	EC:4.1.1.109;RHEA:55532
cellular_component	GO:0062039	biofilm matrix
	xrefs	PMID:28955324	WAS	N/A

752 RELATION CHANGES
molecular_function	GO:0000010	heptaprenyl diphosphate synthase activity
	is_a	GO:0120531	WAS	GO:0004659
molecular_function	GO:0000248	C-5 sterol desaturase activity
	is_a	GO:0070704	WAS	GO:0016717;GO:0070704
molecular_function	GO:0000249	C-22 sterol desaturase (NADPH) activity
	is_a	GO:0070704	WAS	GO:0016717;GO:0070704
molecular_function	GO:0000252	3-beta-hydroxysteroid dehydrogenase [NAD(P)+]/C4-decarboxylase activity
	is_a	GO:0033764	WAS	GO:0016616
molecular_function	GO:0000253	3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity
	is_a	GO:0033764	WAS	GO:0016616
molecular_function	GO:0001537	dermatan 4-sulfotransferase activity
	is_a	GO:0120534	WAS	GO:0008146
molecular_function	GO:0001882	nucleoside binding
	is_a	GO:0097367;GO:1901363	WAS	GO:0097159;GO:0097367;GO:1901363
molecular_function	GO:0002054	nucleobase binding
	is_a	GO:1901363	WAS	GO:0097159;GO:1901363
molecular_function	GO:0003676	nucleic acid binding
	is_a	GO:0005488	WAS	GO:0097159
molecular_function	GO:0003678	DNA helicase activity
	relationship	N/A	WAS	part_of GO:0032508
molecular_function	GO:0003707	nuclear steroid receptor activity
	relationship	part_of GO:0030518	WAS	part_of GO:0043401
molecular_function	GO:0004161	dimethylallyltranstransferase activity
	is_a	GO:0120531	WAS	GO:0004659
molecular_function	GO:0004230	glutamyl aminopeptidase activity
	is_a	GO:0004177	WAS	N/A
molecular_function	GO:0004311	geranylgeranyl diphosphate synthase activity
	is_a	GO:0120531	WAS	GO:0004659
molecular_function	GO:0004337	(2E,6E)-farnesyl diphosphate synthase activity
	is_a	GO:0120531	WAS	GO:0004659
molecular_function	GO:0004508	steroid 17-alpha-monooxygenase activity
	is_a	GO:0008395;GO:0016712	WAS	GO:0008395;GO:0016705
molecular_function	GO:0004509	steroid 21-monooxygenase activity
	is_a	GO:0008395;GO:0016712	WAS	GO:0008395;GO:0016705
molecular_function	GO:0004883	nuclear glucocorticoid receptor activity
	is_a	GO:0003707	WAS	GO:0004879
molecular_function	GO:0005330	dopamine:sodium symporter activity
	is_a	GO:0008504;GO:0015378	WAS	GO:0008504;GO:0015378;GO:1901618
molecular_function	GO:0005334	norepinephrine:sodium symporter activity
	is_a	GO:0008504;GO:0015101;GO:0015378	WAS	GO:0008504;GO:0015101;GO:0015378;GO:1901618
molecular_function	GO:0005335	serotonin:sodium:chloride symporter activity
	is_a	GO:0008504;GO:0015378	WAS	GO:0008504;GO:0015378;GO:1901618
molecular_function	GO:0005461	UDP-glucuronate transmembrane transporter activity
	is_a	GO:0015165;GO:0046943	WAS	GO:0015165
molecular_function	GO:0005496	steroid binding
	is_a	GO:0008289	WAS	GO:0008289;GO:0097159
molecular_function	GO:0005527	macrolide binding
	is_a	GO:0005488	WAS	GO:0097159
molecular_function	GO:0005542	folic acid binding
	is_a	GO:0019842;GO:0031406;GO:0033218;GO:0072341;GO:1901363	WAS	GO:0019842;GO:0031406;GO:0033218;GO:0072341;GO:0097159;GO:1901363
molecular_function	GO:0008123	cholesterol 7-alpha-monooxygenase activity
	is_a	GO:0008387;GO:0016712	WAS	GO:0008387;GO:0016709
molecular_function	GO:0008390	testosterone 16-alpha-hydroxylase activity
	is_a	GO:0008395;GO:0016712	WAS	GO:0008395;GO:0016705
molecular_function	GO:0008412	4-hydroxybenzoate polyprenyltransferase activity
	is_a	GO:0004659	WAS	GO:0002094
molecular_function	GO:0008431	vitamin E binding
	is_a	GO:0019842;GO:1901363	WAS	GO:0019842;GO:0097159;GO:1901363
molecular_function	GO:0008658	penicillin binding
	is_a	GO:0033218;GO:0033293;GO:1901363;GO:1901681	WAS	GO:0033218;GO:0033293;GO:0097159;GO:1901363;GO:1901681
molecular_function	GO:0008834	ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] activity
	is_a	GO:0045547	WAS	GO:0004659
molecular_function	GO:0008886	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity
	is_a	GO:0120533	WAS	GO:0016620
molecular_function	GO:0009374	biotin binding
	is_a	GO:0019842;GO:0033218;GO:0033293;GO:1901363;GO:1901681	WAS	GO:0019842;GO:0033218;GO:0033293;GO:0097159;GO:1901363;GO:1901681
molecular_function	GO:0010013	N-1-naphthylphthalamic acid binding
	is_a	GO:0033218;GO:0033293	WAS	GO:0033218;GO:0033293;GO:0097159
molecular_function	GO:0015125	bile acid transmembrane transporter activity
	is_a	GO:0008028;GO:0170055	WAS	GO:0008028;GO:0170055;GO:1901618
molecular_function	GO:0015129	lactate transmembrane transporter activity
	is_a	GO:0008028	WAS	GO:0008028;GO:1901618
molecular_function	GO:0015166	polyol transmembrane transporter activity
	is_a	GO:0022857	WAS	GO:1901618
molecular_function	GO:0015530	shikimate transmembrane transporter activity
	is_a	GO:0008028	WAS	GO:0008028;GO:1901618
molecular_function	GO:0015551	3-hydroxyphenyl propanoate transmembrane transporter activity
	is_a	GO:0022857	WAS	GO:1901618
molecular_function	GO:0015665	alcohol transmembrane transporter activity
	is_a	GO:0022857	WAS	GO:1901618
molecular_function	GO:0016172	antifreeze activity
	is_a	GO:0050825	WAS	N/A
molecular_function	GO:0016285	alanyl aminopeptidase activity
	is_a	GO:0004177	WAS	N/A
molecular_function	GO:0016596	thienylcyclohexylpiperidine binding
	is_a	GO:1901681	WAS	GO:0097159;GO:1901681
molecular_function	GO:0018592	4-nitrocatechol 4-monooxygenase activity
	is_a	GO:0016709	WAS	GO:0004497;GO:0016705
molecular_function	GO:0018679	dibenzothiophene sulfone monooxygenase (NADH) activity
	is_a	GO:0016712	WAS	GO:0004497;GO:0016705
molecular_function	GO:0019811	cocaine binding
	is_a	GO:0043169;GO:1901363	WAS	GO:0043169;GO:0097159;GO:1901363
molecular_function	GO:0019833	ice nucleation activity
	is_a	GO:0050825	WAS	N/A
molecular_function	GO:0030284	nuclear estrogen receptor activity
	is_a	GO:0003707	WAS	GO:0004879
molecular_function	GO:0030343	vitamin D3 25-hydroxylase activity
	is_a	GO:0008395	WAS	GO:0070643
molecular_function	GO:0030975	thiamine binding
	is_a	GO:0019842;GO:0043169;GO:0043178;GO:1901363;GO:1901681	WAS	GO:0019842;GO:0043169;GO:0043178;GO:0097159;GO:1901363;GO:1901681
molecular_function	GO:0030976	thiamine pyrophosphate binding
	is_a	GO:0019842;GO:0043168;GO:0043169;GO:0050997;GO:1901363;GO:1901681	WAS	GO:0019842;GO:0043168;GO:0043169;GO:0050997;GO:0097159;GO:1901363;GO:1901681
molecular_function	GO:0031073	cholesterol 26-hydroxylase activity
	is_a	GO:0008395;GO:0016716	WAS	GO:0008395
molecular_function	GO:0031405	lipoic acid binding
	is_a	GO:0005504;GO:1901363;GO:1901681	WAS	GO:0005504;GO:0097159;GO:1901363;GO:1901681
molecular_function	GO:0031418	L-ascorbic acid binding
	is_a	GO:0019842;GO:0031406;GO:0048029;GO:1901363	WAS	GO:0019842;GO:0031406;GO:0048029;GO:0097159;GO:1901363
molecular_function	GO:0031925	pyridoxal transmembrane transporter activity
	is_a	GO:0015101	WAS	GO:0015101;GO:1901618
molecular_function	GO:0031926	pyridoxal phosphate transmembrane transporter activity
	is_a	GO:0008514;GO:0015605	WAS	GO:0008514;GO:0015605;GO:1901618
molecular_function	GO:0031927	pyridoxamine transmembrane transporter activity
	is_a	GO:0015101	WAS	GO:0015101;GO:1901618
molecular_function	GO:0031928	pyridoxine transmembrane transporter activity
	is_a	GO:0022857	WAS	GO:1901618
molecular_function	GO:0033294	ectoine binding
	is_a	GO:0033293;GO:1901363	WAS	GO:0033293;GO:0097159;GO:1901363
molecular_function	GO:0033295	hydroxyectoine binding
	is_a	GO:0033293;GO:0043178;GO:0050997;GO:1901363	WAS	GO:0033293;GO:0043178;GO:0050997;GO:0097159;GO:1901363
molecular_function	GO:0033703	3-beta-hydroxy-5-beta-steroid dehydrogenase (NADP+) activity
	is_a	GO:0033764	WAS	GO:0016616
molecular_function	GO:0033704	3-beta-hydroxy-5-alpha-steroid dehydrogenase (NADP+) activity
	is_a	GO:0033764	WAS	GO:0016616
molecular_function	GO:0033782	24S-hydroxycholesterol 7-alpha-hydroxylase activity
	is_a	GO:0008387;GO:0016712	WAS	GO:0008396;GO:0016712
molecular_function	GO:0033783	25-hydroxycholesterol 7-alpha-hydroxylase activity
	is_a	GO:0008387;GO:0016712	WAS	GO:0008396;GO:0016712
molecular_function	GO:0034041	ABC-type sterol transporter activity
	is_a	GO:0034040;GO:0140359	WAS	GO:0034040;GO:0140359;GO:1901618
molecular_function	GO:0034481	chondroitin sulfotransferase activity
	is_a	GO:0050698	WAS	GO:0008146
molecular_function	GO:0034483	heparan sulfate sulfotransferase activity
	is_a	GO:0050698	WAS	GO:0008146
molecular_function	GO:0034617	tetrahydrobiopterin binding
	is_a	GO:0005488	WAS	GO:0097159
molecular_function	GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism
	is_a	GO:0141051;GO:0141221	WAS	GO:0141051
molecular_function	GO:0035273	phthalate binding
	is_a	GO:0031406	WAS	GO:0031406;GO:0097159
molecular_function	GO:0035274	diphenyl phthalate binding
	is_a	GO:0005488	WAS	GO:0097159
molecular_function	GO:0035275	dibutyl phthalate binding
	is_a	GO:0005488	WAS	GO:0097159
molecular_function	GO:0035302	ecdysteroid 25-hydroxylase activity
	is_a	GO:0008395;GO:0016712	WAS	GO:0008395
molecular_function	GO:0035923	flurbiprofen binding
	is_a	GO:0031406	WAS	GO:0031406;GO:0097159
molecular_function	GO:0036310	ATP-dependent DNA/DNA annealing activity
	is_a	GO:0008094;GO:1990814	WAS	GO:0140657;GO:1990814
molecular_function	GO:0036423	hexaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) activity
	is_a	GO:0120531	WAS	GO:0004659
molecular_function	GO:0042767	ecdysteroid 22-hydroxylase activity
	is_a	GO:0008395;GO:0016713	WAS	GO:0008395
molecular_function	GO:0042931	enterobactin transmembrane transporter activity
	is_a	GO:0008514;GO:0015343	WAS	GO:0008514;GO:0015343;GO:1901618
molecular_function	GO:0042934	achromobactin transmembrane transporter activity
	is_a	GO:0015343;GO:0042887;GO:0046943	WAS	GO:0015343;GO:0042887;GO:0046943;GO:1901618
molecular_function	GO:0043544	lipoamide binding
	is_a	GO:0033218;GO:1901681	WAS	GO:0033218;GO:0097159;GO:1901681
molecular_function	GO:0043546	molybdopterin cofactor binding
	is_a	GO:0005488	WAS	GO:0097159
molecular_function	GO:0043878	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity
	is_a	GO:0120533	WAS	GO:0016620
molecular_function	GO:0043924	suramin binding
	is_a	GO:0033218;GO:0043168;GO:0043177;GO:1901681	WAS	GO:0033218;GO:0043168;GO:0043177;GO:0097159;GO:1901681
molecular_function	GO:0044687	geranylfarnesyl diphosphate synthase activity
	is_a	GO:0120531	WAS	GO:0004659
molecular_function	GO:0044875	gamma-glutamyl hercynylcysteine sulfoxide synthase activity
	is_a	GO:0004497;GO:0016705	WAS	GO:0016705
molecular_function	GO:0045130	keratan sulfotransferase activity
	is_a	GO:0050698	WAS	GO:0008146
molecular_function	GO:0045547	ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity
	is_a	GO:0120531	WAS	GO:0004659
molecular_function	GO:0046428	1,4-dihydroxy-2-naphthoate polyprenyltransferase activity
	is_a	GO:0004659	WAS	GO:0002094
molecular_function	GO:0046905	15-cis-phytoene synthase activity
	is_a	GO:0004659	WAS	GO:0016462
molecular_function	GO:0046906	tetrapyrrole binding
	is_a	GO:0005488	WAS	GO:0097159
molecular_function	GO:0047035	testosterone dehydrogenase (NAD+) activity
	is_a	GO:0030283;GO:0044594	WAS	GO:0030283
molecular_function	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity
	is_a	GO:0030283;GO:0072582	WAS	GO:0033764
molecular_function	GO:0047096	androst-4-ene-3,17-dione monooxygenase activity
	is_a	GO:0004508	WAS	GO:0004497;GO:0016705
molecular_function	GO:0047295	geranylgeranylglycerol-phosphate geranylgeranyltransferase activity
	is_a	GO:0004659	WAS	GO:0002094
molecular_function	GO:0047863	dimethylallylcistransferase activity
	is_a	GO:0120531	WAS	GO:0004659
molecular_function	GO:0047882	estradiol 6-beta-monooxygenase activity
	is_a	GO:0008395;GO:0016705	WAS	GO:0004497;GO:0016705
molecular_function	GO:0050016	kynurenine 7,8-hydroxylase activity
	is_a	GO:0004497;GO:0016705	WAS	GO:0016705
molecular_function	GO:0050046	delta7-sterol 5(6)-desaturase activity
	is_a	GO:0070704	WAS	GO:0016717;GO:0070704
molecular_function	GO:0050212	progesterone 11-alpha-monooxygenase activity
	is_a	GO:0050214	WAS	GO:0004497;GO:0016705
molecular_function	GO:0050214	progesterone monooxygenase activity
	is_a	GO:0008395;GO:0016705	WAS	GO:0004497;GO:0016705
molecular_function	GO:0050267	rubber cis-polyprenylcistransferase activity
	is_a	GO:0120531	WAS	GO:0002094
molecular_function	GO:0050292	steroid 9-alpha-monooxygenase activity
	is_a	GO:0008395;GO:0016705	WAS	GO:0004497;GO:0016705
molecular_function	GO:0050604	taxadiene 5-alpha-hydroxylase activity
	is_a	GO:0004497;GO:0016705	WAS	GO:0016705
molecular_function	GO:0050809	diazepam binding
	is_a	GO:0005488	WAS	GO:0097159
molecular_function	GO:0051378	serotonin binding
	is_a	GO:0043169;GO:0043176;GO:1901363	WAS	GO:0043169;GO:0043176;GO:0097159;GO:1901363
molecular_function	GO:0051381	histamine binding
	is_a	GO:0043169;GO:1901363	WAS	GO:0043169;GO:0097159;GO:1901363
molecular_function	GO:0051870	methotrexate binding
	is_a	GO:0031406;GO:0033218;GO:1901363	WAS	GO:0031406;GO:0033218;GO:0097159;GO:1901363
molecular_function	GO:0051871	dihydrofolic acid binding
	is_a	GO:0031406;GO:0072341;GO:1901363	WAS	GO:0031406;GO:0072341;GO:0097159;GO:1901363
molecular_function	GO:0052922	hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific) activity
	is_a	GO:0120531	WAS	GO:0004659
molecular_function	GO:0052923	all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity
	is_a	GO:0120531	WAS	GO:0004659
molecular_function	GO:0052924	all-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) activity
	is_a	GO:0120531	WAS	GO:0004659
molecular_function	GO:0061628	histone H3K27me3 reader activity
	is_a	GO:0140006	WAS	GO:0035064
molecular_function	GO:0062072	histone H3K9me3 reader activity
	is_a	GO:0140006	WAS	GO:0035064
molecular_function	GO:0062179	vitamin D 23-hydroxylase activity
	is_a	GO:0008395	WAS	GO:0004497
molecular_function	GO:0062184	testosterone 16-beta-hydroxylase activity
	is_a	GO:0008395	WAS	GO:0004497
molecular_function	GO:0070279	vitamin B6 binding
	is_a	GO:0019842;GO:1901363	WAS	GO:0019842;GO:0097159;GO:1901363
molecular_function	GO:0070576	vitamin D 24-hydroxylase activity
	is_a	GO:0008395	WAS	GO:0004497
molecular_function	GO:0070704	sterol desaturase activity
	is_a	GO:0016717	WAS	GO:0016705
molecular_function	GO:0070908	tyrosine:tyramine antiporter activity
	is_a	GO:0005302;GO:0008504;GO:0015297	WAS	GO:0005302;GO:0008504;GO:0015297;GO:1901618
molecular_function	GO:0070967	coenzyme F420 binding
	is_a	GO:0031406;GO:0097367;GO:1901363	WAS	GO:0031406;GO:0097159;GO:0097367;GO:1901363
molecular_function	GO:0070968	pyrroloquinoline quinone binding
	is_a	GO:0031406;GO:1901363	WAS	GO:0031406;GO:0097159;GO:1901363
molecular_function	GO:0071886	1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
	is_a	GO:0043176	WAS	GO:0043176;GO:0097159
molecular_function	GO:0072544	L-DOPA binding
	is_a	GO:0016597;GO:0031406;GO:0072341	WAS	GO:0016597;GO:0031406;GO:0072341;GO:0097159
molecular_function	GO:0072545	L-tyrosine binding
	is_a	GO:0016597;GO:0031406;GO:0043169	WAS	GO:0016597;GO:0031406;GO:0043169;GO:0097159
molecular_function	GO:0097160	polychlorinated biphenyl binding
	is_a	GO:0005488	WAS	GO:0097159
molecular_function	GO:0097245	flavanol binding
	is_a	GO:0097243;GO:1901363	WAS	GO:0097159;GO:0097243;GO:1901363
molecular_function	GO:0097247	epigallocatechin 3-gallate binding
	is_a	GO:0097243	WAS	GO:0097159;GO:0097243
molecular_function	GO:0097269	all-trans-decaprenyl-diphosphate synthase activity
	is_a	GO:0120531	WAS	GO:0004659
molecular_function	GO:0101020	estrogen 16-alpha-hydroxylase activity
	is_a	GO:0008395;GO:0016712	WAS	GO:0008395;GO:0016705
molecular_function	GO:0101021	estrogen 2-hydroxylase activity
	is_a	GO:0008395;GO:0016712	WAS	GO:0008395;GO:0016705
molecular_function	GO:0102059	(2Z,6Z)-farnesyl diphosphate synthase activity
	is_a	GO:0120531	WAS	GO:0016765
molecular_function	GO:0102142	dermatan 2-sulfotransferase activity
	is_a	GO:0120534	WAS	GO:0008146
molecular_function	GO:0102175	3-beta-hydroxysteroid dehydrogenase (NAD+)/C4-decarboxylase activity
	is_a	GO:0000252	WAS	GO:0016616
molecular_function	GO:0102733	typhasterol C-23 hydroxylase activity
	is_a	GO:0004497;GO:0016705	WAS	GO:0016705
molecular_function	GO:0106240	labd-13Z-ene-9,15,16-triol synthase activity
	is_a	GO:0016712	WAS	GO:0016705
molecular_function	GO:0106350	all-trans-octaprenyl-diphosphate synthase activity
	is_a	GO:0120531	WAS	GO:0004659
molecular_function	GO:0120284	tryptophan binding
	is_a	GO:0016597;GO:0031406;GO:0043169;GO:1901363	WAS	GO:0016597;GO:0031406;GO:0043169;GO:0097159;GO:1901363
molecular_function	GO:0140566	histone reader activity
	is_a	GO:0030674	WAS	GO:0140463
molecular_function	GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism
	is_a	GO:0141051;GO:0141221	WAS	GO:0141051
molecular_function	GO:0160191	steroid 22S-hydroxylase activity
	is_a	GO:0008395;GO:0016712	WAS	GO:0016712
molecular_function	GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism
	is_a	GO:0141051;GO:0141221	WAS	GO:0141051
molecular_function	GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism
	is_a	GO:0141051;GO:0141221	WAS	GO:0141051
molecular_function	GO:1901149	salicylic acid binding
	is_a	GO:0033293	WAS	GO:0033293;GO:0097159
molecular_function	GO:1901241	4-hydroxyphenylacetate transmembrane transporter activity
	is_a	GO:0008028	WAS	GO:0008028;GO:1901618
molecular_function	GO:1901265	nucleoside phosphate binding
	is_a	GO:0005488	WAS	GO:0097159
molecular_function	GO:1901338	catecholamine binding
	is_a	GO:0005488	WAS	GO:0097159
molecular_function	GO:1901602	dethiobiotin binding
	is_a	GO:0033218;GO:0033293;GO:1901363	WAS	GO:0033218;GO:0033293;GO:0097159;GO:1901363
molecular_function	GO:1901707	leptomycin B binding
	is_a	GO:0005504;GO:1901363	WAS	GO:0005504;GO:0097159;GO:1901363
molecular_function	GO:1901973	proline binding
	is_a	GO:0016597;GO:0031406;GO:1901363	WAS	GO:0016597;GO:0031406;GO:0097159;GO:1901363
molecular_function	GO:1902314	hydroquinone binding
	is_a	GO:0005488	WAS	GO:0097159
molecular_function	GO:1902444	riboflavin binding
	is_a	GO:0043168;GO:1901363	WAS	GO:0043168;GO:0097159;GO:1901363
molecular_function	GO:1904408	melatonin binding
	is_a	GO:0033218	WAS	GO:0033218;GO:0097159
molecular_function	GO:1905594	resveratrol binding
	is_a	GO:0005488	WAS	GO:0097159
molecular_function	GO:2001147	camalexin binding
	is_a	GO:1901681	WAS	GO:0097159;GO:1901681
biological_process	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
	is_a	GO:0071900	WAS	GO:0071900;GO:1904029
biological_process	GO:0000162	L-tryptophan biosynthetic process
	is_a	GO:0006568;GO:0009073;GO:0046219;GO:1902223	WAS	GO:0009073;GO:0046219;GO:1901607
biological_process	GO:0002323	natural killer cell activation involved in immune response
	relationship	part_of GO:0045087	WAS	N/A
	intersection_of	is_a GO:0030101;part_of GO:0045087	WAS	is_a GO:0030101;part_of GO:0006955
biological_process	GO:0002324	natural killer cell proliferation involved in immune response
	is_a	GO:0001787;GO:0002285	WAS	GO:0001787;GO:0002323
biological_process	GO:0002325	natural killer cell differentiation involved in immune response
	is_a	GO:0001779;GO:0002285	WAS	GO:0001779;GO:0002323
biological_process	GO:0006066	alcohol metabolic process
	is_a	GO:0044281	WAS	GO:0044281;GO:1901615
biological_process	GO:0006089	lactate metabolic process
	is_a	GO:0032787	WAS	GO:0032787;GO:1901615
biological_process	GO:0006127	glycerol-3-phosphate shuttle
	is_a	GO:0006116	WAS	GO:0006116;GO:0018958;GO:1901661
	relationship	has_part GO:0004368;has_part GO:0141152	WAS	has_part GO:0004368;has_part GO:0141152;part_of GO:0022904
biological_process	GO:0006569	L-tryptophan catabolic process
	is_a	GO:0006568;GO:0009074;GO:0042436;GO:1902222	WAS	GO:0006586;GO:0009074;GO:0042436;GO:1901606
biological_process	GO:0006699	bile acid biosynthetic process
	is_a	GO:0008206;GO:0072330	WAS	GO:0006694;GO:0008206;GO:0072330;GO:1901617
biological_process	GO:0007194	negative regulation of adenylate cyclase activity
	is_a	GO:0045761;GO:0051350	WAS	GO:0031280;GO:0045761;GO:0051350
biological_process	GO:0008206	bile acid metabolic process
	is_a	GO:0008202;GO:0032787	WAS	GO:0008202;GO:0032787;GO:1901615
biological_process	GO:0008614	pyridoxine metabolic process
	is_a	GO:0042816	WAS	GO:0042816;GO:1901615
biological_process	GO:0008615	pyridoxine biosynthetic process
	is_a	GO:0008614;GO:0042819	WAS	GO:0008614;GO:0042819;GO:1901617
biological_process	GO:0009051	pentose-phosphate shunt, oxidative branch
	is_a	GO:0006740;GO:1901135	WAS	GO:0006740;GO:0051156
	relationship	has_part GO:0004345;has_part GO:0004616;has_part GO:0017057;part_of GO:0006098	WAS	has_part GO:0004341;has_part GO:0004345;has_part GO:0004616;part_of GO:0006098
biological_process	GO:0009271	phage shock
	is_a	GO:0006950	WAS	GO:0006950;GO:0098586
biological_process	GO:0009741	response to brassinosteroid
	is_a	GO:0009725;GO:0033993;GO:1901700	WAS	GO:0009725;GO:0014070;GO:0033993;GO:1901700
biological_process	GO:0009751	response to salicylic acid
	is_a	GO:1901700	WAS	GO:0014070;GO:1901700
biological_process	GO:0010115	regulation of abscisic acid biosynthetic process
	is_a	GO:0019747;GO:0046890;GO:1902930	WAS	GO:0010565;GO:0019747;GO:0043455;GO:0046890;GO:1902930
biological_process	GO:0010189	vitamin E biosynthetic process
	is_a	GO:0042360;GO:0042362	WAS	GO:0042360;GO:0042362;GO:1901617
biological_process	GO:0010238	response to proline
	is_a	GO:0043200;GO:1901698;GO:1901700	WAS	GO:0014070;GO:0043200;GO:1901698;GO:1901700
biological_process	GO:0010266	response to vitamin B1
	is_a	GO:0033273;GO:0097305;GO:1901698	WAS	GO:0014070;GO:0033273;GO:0097305;GO:1901698
biological_process	GO:0010517	regulation of phospholipase activity
	is_a	GO:0051336	WAS	GO:0060191
biological_process	GO:0010583	response to cyclopentenone
	is_a	GO:0042221	WAS	GO:0014070
biological_process	GO:0010722	regulation of ferrochelatase activity
	is_a	GO:0050790	WAS	GO:0051339
biological_process	GO:0010883	regulation of lipid storage
	is_a	GO:0050794	WAS	GO:0032879
biological_process	GO:0010884	positive regulation of lipid storage
	is_a	GO:0010883;GO:0048522;GO:1905954	WAS	GO:0010883;GO:1905954
biological_process	GO:0010888	negative regulation of lipid storage
	is_a	GO:0010883;GO:0048523;GO:1905953	WAS	GO:0010883;GO:1905953
biological_process	GO:0010925	positive regulation of inositol-polyphosphate 5-phosphatase activity
	is_a	GO:0010922	WAS	GO:0010922;GO:0010924
biological_process	GO:0010980	positive regulation of vitamin D 24-hydroxylase activity
	is_a	GO:0032770	WAS	GO:0010979;GO:0032770
biological_process	GO:0014071	response to cycloalkane
	is_a	GO:0042221	WAS	GO:0014070
biological_process	GO:0014072	response to isoquinoline alkaloid
	is_a	GO:0043279	WAS	GO:0014070;GO:0043279
biological_process	GO:0014073	response to tropane
	is_a	GO:0043279	WAS	GO:0014070;GO:0043279
biological_process	GO:0014074	response to purine-containing compound
	is_a	GO:1901698	WAS	GO:0014070;GO:1901698
biological_process	GO:0015012	heparan sulfate proteoglycan biosynthetic process
	is_a	GO:0030166;GO:0030201;GO:0044272	WAS	GO:0030166;GO:0044272
biological_process	GO:0016125	sterol metabolic process
	is_a	GO:0008202	WAS	GO:0008202;GO:1901615
biological_process	GO:0016126	sterol biosynthetic process
	is_a	GO:0006694;GO:0016125	WAS	GO:0006694;GO:0016125;GO:1901617
biological_process	GO:0016127	sterol catabolic process
	is_a	GO:0006706;GO:0016125	WAS	GO:0006706;GO:0016125;GO:1901616
biological_process	GO:0016128	phytosteroid metabolic process
	is_a	GO:0008202	WAS	GO:0008202;GO:1901615
biological_process	GO:0016129	phytosteroid biosynthetic process
	is_a	GO:0006694;GO:0016128	WAS	GO:0006694;GO:0016128;GO:1901617
biological_process	GO:0016130	phytosteroid catabolic process
	is_a	GO:0006706;GO:0016128	WAS	GO:0006706;GO:0016128;GO:1901616
biological_process	GO:0018924	mandelate metabolic process
	is_a	GO:0032787;GO:0042537	WAS	GO:0032787;GO:0042537;GO:1901615
biological_process	GO:0018958	phenol-containing compound metabolic process
	is_a	GO:0008152	WAS	GO:1901615
biological_process	GO:0019057	symbiont-mediated perturbation of host translation
	is_a	GO:0039656	WAS	GO:0044068
biological_process	GO:0019065	receptor-mediated endocytosis of virus by host cell
	relationship	part_of GO:0046718	WAS	N/A
biological_process	GO:0019087	symbiont-mediated transformation of host cell
	is_a	GO:0044068	WAS	GO:0019054
biological_process	GO:0019249	lactate biosynthetic process
	is_a	GO:0006089;GO:0072330	WAS	GO:0006089;GO:0072330;GO:1901617
biological_process	GO:0019336	phenol-containing compound catabolic process
	is_a	GO:0009056;GO:0018958	WAS	GO:0018958;GO:1901616
biological_process	GO:0019391	glucuronoside catabolic process
	is_a	GO:0016139	WAS	N/A
biological_process	GO:0019444	L-tryptophan catabolic process to catechol
	is_a	GO:0006586;GO:0009074;GO:0009712;GO:0042436;GO:1901606	WAS	GO:0006569;GO:0009712
biological_process	GO:0019596	mandelate catabolic process
	is_a	GO:0018924;GO:0072329	WAS	GO:0018924;GO:0072329;GO:1901616
biological_process	GO:0019632	shikimate metabolic process
	is_a	GO:0032787	WAS	GO:0032787;GO:1901615
biological_process	GO:0019633	shikimate catabolic process
	is_a	GO:0019632;GO:0072329	WAS	GO:0019632;GO:0072329;GO:1901616
biological_process	GO:0019915	lipid storage
	is_a	GO:0170062	WAS	GO:0051235
	relationship	N/A	WAS	part_of GO:0010876
biological_process	GO:0030200	heparan sulfate proteoglycan catabolic process
	is_a	GO:0030167;GO:0030201;GO:0044273	WAS	GO:0030167;GO:0044273
biological_process	GO:0030201	heparan sulfate proteoglycan metabolic process
	is_a	GO:0006029;GO:0006790	WAS	GO:0006029
biological_process	GO:0031001	response to brefeldin A
	is_a	GO:0046677;GO:1901700	WAS	GO:0014070;GO:0046677;GO:1901700
biological_process	GO:0031281	positive regulation of cyclase activity
	is_a	GO:0043085	WAS	GO:0031279;GO:0043085
biological_process	GO:0031282	regulation of guanylate cyclase activity
	is_a	GO:0050790;GO:1900371	WAS	GO:0031279;GO:0051339;GO:1900371
biological_process	GO:0031283	negative regulation of guanylate cyclase activity
	is_a	GO:0031282;GO:0051350;GO:1900372	WAS	GO:0031280;GO:0031282;GO:0051350;GO:1900372
biological_process	GO:0031427	response to methotrexate
	is_a	GO:1901698;GO:1901700	WAS	GO:0014070;GO:1901698;GO:1901700
biological_process	GO:0031509	subtelomeric heterochromatin formation
	relationship	occurs_in GO:0000781	WAS	occurs_in GO:0000781;part_of GO:0032200
biological_process	GO:0031990	mRNA export from nucleus in response to heat stress
	is_a	GO:0006406;GO:0034605;GO:1901698	WAS	GO:0006406;GO:0014070;GO:0034605;GO:1901698
biological_process	GO:0032071	regulation of endodeoxyribonuclease activity
	is_a	GO:0051336	WAS	GO:0032070
biological_process	GO:0032074	negative regulation of nuclease activity
	is_a	GO:0045934;GO:0051346	WAS	GO:0032069;GO:0045934;GO:0051346
biological_process	GO:0032075	positive regulation of nuclease activity
	is_a	GO:0045935;GO:0051345	WAS	GO:0032069;GO:0045935;GO:0051345
biological_process	GO:0032076	negative regulation of deoxyribonuclease activity
	is_a	GO:0032074;GO:0051053	WAS	GO:0032070;GO:0032074;GO:0051053
biological_process	GO:0032077	positive regulation of deoxyribonuclease activity
	is_a	GO:0032075;GO:0051054	WAS	GO:0032070;GO:0032075;GO:0051054
biological_process	GO:0032355	response to estradiol
	is_a	GO:0033993;GO:1901700	WAS	GO:0014070;GO:0033993;GO:1901700
biological_process	GO:0032361	pyridoxal phosphate catabolic process
	is_a	GO:0042820;GO:0042822;GO:0046185;GO:0046434	WAS	GO:0042820;GO:0042822;GO:0046185;GO:0046434;GO:1901616
biological_process	GO:0032416	negative regulation of sodium:proton antiporter activity
	is_a	GO:2000650	WAS	GO:0032415;GO:2000650
biological_process	GO:0032417	positive regulation of sodium:proton antiporter activity
	is_a	GO:2000651	WAS	GO:0032415;GO:2000651
biological_process	GO:0032769	negative regulation of monooxygenase activity
	is_a	GO:0051354	WAS	GO:0032768;GO:0051354
biological_process	GO:0032770	positive regulation of monooxygenase activity
	is_a	GO:0051353	WAS	GO:0032768;GO:0051353
biological_process	GO:0032773	positive regulation of tyrosinase activity
	is_a	GO:0032770	WAS	GO:0032770;GO:0032771
biological_process	GO:0032981	mitochondrial respiratory chain complex I assembly
	is_a	GO:0010257;GO:0033108	WAS	GO:0010257;GO:0033108;GO:0097250
biological_process	GO:0033108	mitochondrial respiratory chain complex assembly
	relationship	occurs_in GO:0005739;part_of GO:0007005	WAS	part_of GO:0007005
biological_process	GO:0033132	negative regulation of glucokinase activity
	is_a	GO:1903300	WAS	GO:0033131;GO:1903300
biological_process	GO:0033133	positive regulation of glucokinase activity
	is_a	GO:1903301	WAS	GO:0033131;GO:1903301
biological_process	GO:0033197	response to vitamin E
	is_a	GO:0033273;GO:1901700	WAS	GO:0014070;GO:0033273;GO:1901700
biological_process	GO:0033274	response to vitamin B2
	is_a	GO:0033273;GO:1901698;GO:1901700	WAS	GO:0014070;GO:0033273;GO:1901698;GO:1901700
biological_process	GO:0033280	response to vitamin D
	is_a	GO:0033273;GO:0033993;GO:1901700	WAS	GO:0014070;GO:0033273;GO:0033993;GO:1901700
biological_process	GO:0033329	kaempferol O-glucoside metabolic process
	is_a	GO:0051552;GO:1901804	WAS	GO:0051552;GO:1901615;GO:1901804
biological_process	GO:0033330	kaempferol O-glucoside biosynthetic process
	is_a	GO:0033329;GO:0051553;GO:1901806	WAS	GO:0033329;GO:0051553;GO:1901617;GO:1901806
biological_process	GO:0033342	negative regulation of collagen binding
	is_a	GO:0051100	WAS	GO:0033341;GO:0051100
biological_process	GO:0033387	putrescine biosynthetic process from arginine, via ornithine
	is_a	GO:0033388	WAS	GO:0006591;GO:0009446
biological_process	GO:0033388	putrescine biosynthetic process from arginine
	is_a	GO:0006525;GO:0009064;GO:0009446	WAS	GO:0006525;GO:0009446
biological_process	GO:0033510	luteolin metabolic process
	is_a	GO:0051552	WAS	GO:0051552;GO:1901615
biological_process	GO:0033511	luteolin biosynthetic process
	is_a	GO:0033510;GO:0051553	WAS	GO:0033510;GO:0051553;GO:1901617
biological_process	GO:0033574	response to testosterone
	is_a	GO:0033993;GO:1901654	WAS	GO:0014070;GO:0033993;GO:1901654
biological_process	GO:0033590	response to cobalamin
	is_a	GO:0033273;GO:1901698;GO:1901700	WAS	GO:0014070;GO:0033273;GO:1901698;GO:1901700
biological_process	GO:0033591	response to L-ascorbic acid
	is_a	GO:0033273;GO:0034284	WAS	GO:0014070;GO:0033273;GO:0034284
biological_process	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly
	is_a	GO:0033108;GO:0043461	WAS	GO:0043461;GO:0097250
	relationship	N/A	WAS	part_of GO:0007005
biological_process	GO:0033617	mitochondrial cytochrome c oxidase assembly
	is_a	GO:0008535;GO:0033108	WAS	GO:0008535;GO:0033108;GO:0097250
biological_process	GO:0033668	symbiont-mediated suppression of host apoptosis
	is_a	GO:0052041;GO:0052150	WAS	GO:0052041
biological_process	GO:0034055	effector-mediated activation of host programmed cell death by symbiont
	is_a	GO:0052042;GO:0140403	WAS	GO:0034053;GO:0052042;GO:0052170;GO:0140418
biological_process	GO:0034354	'de novo' NAD biosynthetic process from tryptophan
	is_a	GO:0034627	WAS	GO:0006568;GO:0034627
biological_process	GO:0034516	response to vitamin B6
	is_a	GO:0033273;GO:1901698;GO:1901700	WAS	GO:0014070;GO:0033273;GO:1901698;GO:1901700
biological_process	GO:0034551	mitochondrial respiratory chain complex III assembly
	is_a	GO:0017062;GO:0033108	WAS	GO:0017062;GO:0033108;GO:0097250
biological_process	GO:0034553	mitochondrial respiratory chain complex II assembly
	is_a	GO:0033108;GO:0034552	WAS	GO:0033108;GO:0034552;GO:0097250
biological_process	GO:0034697	response to prostaglandin I
	is_a	GO:0034694;GO:1901700	WAS	GO:0014070;GO:0034694;GO:1901700
biological_process	GO:0034776	response to histamine
	is_a	GO:1901698	WAS	GO:0014070;GO:1901698
biological_process	GO:0035229	positive regulation of glutamate-cysteine ligase activity
	is_a	GO:0051351	WAS	GO:0035227;GO:0051351
biological_process	GO:0035562	negative regulation of chromatin binding
	is_a	GO:0051100	WAS	GO:0035561;GO:0051100
biological_process	GO:0035563	positive regulation of chromatin binding
	is_a	GO:0051099	WAS	GO:0035561;GO:0051099
biological_process	GO:0035634	response to stilbenoid
	is_a	GO:0042221	WAS	GO:0014070
biological_process	GO:0035832	berbamunine metabolic process
	is_a	GO:0046445	WAS	GO:0046445;GO:1901615
biological_process	GO:0035833	berbamunine biosynthetic process
	is_a	GO:0009708;GO:0035832	WAS	GO:0009708;GO:0035832;GO:1901617
biological_process	GO:0035983	response to trichostatin A
	is_a	GO:0046677;GO:1901698;GO:1901700	WAS	GO:0014070;GO:0046677;GO:1901698;GO:1901700
biological_process	GO:0035984	cellular response to trichostatin A
	is_a	GO:0035983;GO:0071236;GO:1901699;GO:1901701	WAS	GO:0035983;GO:0071236;GO:0071407;GO:1901699;GO:1901701
biological_process	GO:0036101	leukotriene B4 catabolic process
	is_a	GO:0036100;GO:0036102;GO:0042758;GO:1901523	WAS	GO:0036100;GO:0036102;GO:0042758;GO:1901523;GO:1901616
biological_process	GO:0036102	leukotriene B4 metabolic process
	is_a	GO:0001676;GO:0006691;GO:1901568	WAS	GO:0001676;GO:0006691;GO:1901568;GO:1901615
biological_process	GO:0036241	glutamate catabolic process to 4-hydroxybutyrate
	is_a	GO:0006538;GO:0046459	WAS	GO:0006538;GO:0046459;GO:1901615
biological_process	GO:0036272	response to gemcitabine
	is_a	GO:1901698;GO:1901700	WAS	GO:0014070;GO:1901698;GO:1901700
biological_process	GO:0036274	response to lapatinib
	is_a	GO:1901698;GO:1901700	WAS	GO:0014070;GO:1901698;GO:1901700
biological_process	GO:0036275	response to 5-fluorouracil
	is_a	GO:0042221	WAS	GO:0014070
biological_process	GO:0036287	response to iloperidone
	is_a	GO:0045472;GO:0071867;GO:1901654	WAS	GO:0014070;GO:0045472;GO:0071867;GO:1901654
biological_process	GO:0036288	response to ximelagatran
	is_a	GO:1901698;GO:1901700	WAS	GO:0014070;GO:1901698;GO:1901700
biological_process	GO:0036314	response to sterol
	is_a	GO:0033993;GO:1901700	WAS	GO:0014070;GO:0033993;GO:1901700
biological_process	GO:0036315	cellular response to sterol
	is_a	GO:0036314;GO:0071396;GO:1901701	WAS	GO:0036314;GO:0071396;GO:0071407;GO:1901701
biological_process	GO:0036522	symbiont-mediated suppression of host protein localization to phagocytic vesicle
	is_a	GO:0044068	WAS	GO:0044003
biological_process	GO:0039520	symbiont-mediated activation of host autophagy
	is_a	GO:0075071	WAS	GO:0010508;GO:0039519;GO:0044068
	intersection_of	N/A	WAS	is_a GO:0044068;positively_regulates GO:0006914
biological_process	GO:0039522	symbiont-mediated suppression of host mRNA export from nucleus
	is_a	GO:0039657;GO:0052038	WAS	GO:0044003
biological_process	GO:0039524	symbiont-mediated suppression of host mRNA processing
	is_a	GO:0039656	WAS	GO:0044003
biological_process	GO:0039587	symbiont-mediated-mediated suppression of host tetherin activity
	is_a	GO:0052031	WAS	GO:0019049
biological_process	GO:0039592	symbiont-mediated arrest of host cell cycle during G2/M transition
	is_a	GO:0044071	WAS	GO:0044003
biological_process	GO:0039595	symbiont-mediated degradation of host mRNA
	is_a	GO:0039656	WAS	GO:0044068
biological_process	GO:0039602	symbiont-mediated suppression of host transcription initiation from RNA polymerase II promoter
	is_a	GO:0039656	WAS	GO:0044003
biological_process	GO:0039604	symbiont-mediated suppression of host translation
	is_a	GO:0019057	WAS	GO:0044003
biological_process	GO:0039606	symbiont-mediated suppression of host translation initiation
	is_a	GO:0039656	WAS	GO:0044003
biological_process	GO:0039635	symbiont-mediated suppression of host peptidoglycan biosynthetic process
	is_a	GO:0044068	WAS	GO:0039636
biological_process	GO:0039636	symbiont-mediated suppression of host cell wall biogenesis
	is_a	GO:0044068	WAS	GO:0019054
biological_process	GO:0039639	suppression by virus of host cell lysis in response to superinfection
	is_a	GO:0016032	WAS	GO:0098586
biological_process	GO:0039653	symbiont-mediated suppression of host transcription
	is_a	GO:0052026	WAS	GO:0044003
biological_process	GO:0039657	symbiont-mediated suppression of host gene expression
	is_a	GO:0039656	WAS	GO:0044003
biological_process	GO:0039671	symbiont-mediated perturbation of host natural killer cell mediated immune response
	is_a	GO:0044068;GO:0052167	WAS	GO:0019049
biological_process	GO:0039673	symbiont-mediated suppression of host dendritic cell mediated immune response
	is_a	GO:0052167	WAS	GO:0019049
biological_process	GO:0039674	exit of virus from host cell nucleus
	is_a	GO:0016032;GO:0035891	WAS	GO:0035891
biological_process	GO:0042199	cyanuric acid metabolic process
	is_a	GO:0018965	WAS	GO:0018965;GO:1901615
biological_process	GO:0042200	cyanuric acid catabolic process
	is_a	GO:0042199;GO:0042204	WAS	GO:0042199;GO:0042204;GO:1901616
biological_process	GO:0042220	response to cocaine
	is_a	GO:0043279;GO:1901700	WAS	GO:0014070;GO:0043279;GO:1901700
biological_process	GO:0042359	vitamin D metabolic process
	is_a	GO:0006775;GO:0008202	WAS	GO:0006775;GO:0008202;GO:1901615
biological_process	GO:0042360	vitamin E metabolic process
	is_a	GO:0006775	WAS	GO:0006775;GO:1901615
biological_process	GO:0042368	vitamin D biosynthetic process
	is_a	GO:0006694;GO:0042359;GO:0042362	WAS	GO:0006694;GO:0042359;GO:0042362;GO:1901617
biological_process	GO:0042369	vitamin D catabolic process
	is_a	GO:0006706;GO:0042359;GO:0042363	WAS	GO:0006706;GO:0042359;GO:0042363;GO:1901616
biological_process	GO:0042817	pyridoxal metabolic process
	is_a	GO:0006081;GO:0042816	WAS	GO:0006081;GO:0042816;GO:1901615
biological_process	GO:0042818	pyridoxamine metabolic process
	is_a	GO:0042816	WAS	GO:0042816;GO:1901615
biological_process	GO:0042821	pyridoxal biosynthetic process
	is_a	GO:0042817;GO:0042819;GO:0046184	WAS	GO:0042817;GO:0042819;GO:0046184;GO:1901617
biological_process	GO:0042822	pyridoxal phosphate metabolic process
	is_a	GO:0006081;GO:0006796;GO:0019637;GO:0042816	WAS	GO:0006081;GO:0006796;GO:0019637;GO:0042816;GO:1901615
biological_process	GO:0042823	pyridoxal phosphate biosynthetic process
	is_a	GO:0042819;GO:0042822;GO:0046184;GO:0090407	WAS	GO:0042819;GO:0042822;GO:0046184;GO:0090407;GO:1901617
biological_process	GO:0042860	achromobactin metabolic process
	is_a	GO:0009237;GO:0019752;GO:0043603	WAS	GO:0009237;GO:0019752;GO:0043603;GO:1901615
biological_process	GO:0042861	achromobactin biosynthetic process
	is_a	GO:0019290;GO:0042860;GO:0043604;GO:0046394	WAS	GO:0019290;GO:0042860;GO:0043604;GO:0046394;GO:1901617
biological_process	GO:0042862	achromobactin catabolic process
	is_a	GO:0042860;GO:0046215;GO:0046395	WAS	GO:0042860;GO:0046215;GO:0046395;GO:1901616
biological_process	GO:0043331	response to dsRNA
	is_a	GO:1901698	WAS	GO:0014070;GO:1901698
biological_process	GO:0043490	malate-aspartate shuttle
	is_a	GO:0006116	WAS	GO:1990542
	relationship	has_part GO:0004069;has_part GO:0030060;has_part GO:1990542	WAS	part_of GO:0022904
biological_process	GO:0044361	negative regulation of voltage-gated potassium channel activity in another organism
	is_a	GO:0044360	WAS	GO:0044360;GO:0044362
biological_process	GO:0044489	negative regulation of voltage-gated sodium channel activity in another organism
	is_a	GO:0044488	WAS	GO:0044362;GO:0044488
biological_process	GO:0044490	positive regulation of voltage-gated sodium channel activity in another organism
	is_a	GO:0044488	WAS	GO:0044488;GO:0044491
biological_process	GO:0044505	positive regulation of G protein-coupled receptor activity in another organism
	is_a	GO:0044503;GO:2000273	WAS	GO:0044503;GO:0044507;GO:2000273
biological_process	GO:0044509	envenomation resulting in modulation of signal transduction in another organism
	relationship	N/A	WAS	has_part GO:0044501
biological_process	GO:0044542	symbiont-mediated activation of host plasminogen
	is_a	GO:0044068	WAS	GO:0044003
biological_process	GO:0044759	symbiont-mediated suppression of host synaptic transmission
	is_a	GO:0044758	WAS	GO:0044758;GO:0050805
biological_process	GO:0044761	symbiont-mediated suppression of host cholinergic synaptic transmission
	is_a	GO:0044759;GO:0044760	WAS	GO:0044003
biological_process	GO:0044865	symbiont-mediated suppression of host cell division
	is_a	GO:0044068	WAS	GO:0044863;GO:0051782
biological_process	GO:0045122	aflatoxin biosynthetic process
	is_a	GO:0006083;GO:0043386;GO:0046222	WAS	GO:0006083;GO:0043386;GO:0046222;GO:1901378
biological_process	GO:0045460	sterigmatocystin metabolic process
	is_a	GO:0009404	WAS	GO:0009404;GO:1901376
biological_process	GO:0045461	sterigmatocystin biosynthetic process
	is_a	GO:0009403;GO:0045460	WAS	GO:0009403;GO:0045460;GO:1901378
biological_process	GO:0045574	sterigmatocystin catabolic process
	is_a	GO:0009407;GO:0045460	WAS	GO:0009407;GO:0045460;GO:1901377
biological_process	GO:0045761	regulation of adenylate cyclase activity
	is_a	GO:0050790	WAS	GO:0031279;GO:0051339
biological_process	GO:0046164	alcohol catabolic process
	is_a	GO:0006066;GO:0044282	WAS	GO:0006066;GO:0044282;GO:1901616
biological_process	GO:0046165	alcohol biosynthetic process
	is_a	GO:0006066;GO:0044283	WAS	GO:0006066;GO:0044283;GO:1901617
biological_process	GO:0046189	phenol-containing compound biosynthetic process
	is_a	GO:0009058;GO:0018958	WAS	GO:0018958;GO:1901617
biological_process	GO:0046222	aflatoxin metabolic process
	is_a	GO:0043385	WAS	GO:0043385;GO:1901376
biological_process	GO:0046223	aflatoxin catabolic process
	is_a	GO:0043387;GO:0046222	WAS	GO:0043387;GO:0046222;GO:1901377
biological_process	GO:0046236	mandelate biosynthetic process
	is_a	GO:0018924;GO:0072330	WAS	GO:0018924;GO:0072330;GO:1901617
biological_process	GO:0046375	K antigen metabolic process
	is_a	GO:0043170;GO:1901135	WAS	GO:0005976;GO:1901135
biological_process	GO:0046597	host-mediated suppression of symbiont invasion
	is_a	GO:0045087;GO:0051851	WAS	GO:0046596;GO:1903901
	relationship	N/A	WAS	negatively_regulates GO:0046718
	intersection_of	N/A	WAS	is_a GO:0065007;negatively_regulates GO:0046718
biological_process	GO:0046680	response to DDT
	is_a	GO:0017085	WAS	GO:0014070;GO:0017085
biological_process	GO:0046773	symbiont-mediated suppression of host translation termination
	is_a	GO:0039656	WAS	GO:0044003
biological_process	GO:0046780	symbiont-mediated suppression of host mRNA splicing
	is_a	GO:0039524	WAS	GO:0033119;GO:0039524
biological_process	GO:0046784	viral mRNA export from host cell nucleus
	is_a	GO:0016032	WAS	GO:0044417
	relationship	part_of GO:0019080	WAS	N/A
biological_process	GO:0046898	response to cycloheximide
	is_a	GO:0097305;GO:1901654;GO:1901698	WAS	GO:0014070;GO:0097305;GO:1901654;GO:1901698
biological_process	GO:0048545	response to steroid hormone
	is_a	GO:0009725;GO:0033993	WAS	GO:0009725;GO:0014070;GO:0033993
biological_process	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process
	is_a	GO:0006024;GO:0030166;GO:0044272;GO:0050654	WAS	GO:0030166;GO:0050654
biological_process	GO:0050654	chondroitin sulfate proteoglycan metabolic process
	is_a	GO:0006029;GO:0006790;GO:0030203	WAS	GO:0006029
biological_process	GO:0050999	regulation of nitric-oxide synthase activity
	is_a	GO:0051341	WAS	GO:0032768
biological_process	GO:0051005	negative regulation of lipoprotein lipase activity
	is_a	GO:0060192	WAS	GO:0051004;GO:0060192
biological_process	GO:0051006	positive regulation of lipoprotein lipase activity
	is_a	GO:0061365	WAS	GO:0051004;GO:0061365
biological_process	GO:0051096	positive regulation of helicase activity
	is_a	GO:0032781;GO:0043085	WAS	GO:0032781;GO:0043085;GO:0051095
biological_process	GO:0051097	negative regulation of helicase activity
	is_a	GO:0032780;GO:0043086	WAS	GO:0032780;GO:0043086;GO:0051095
biological_process	GO:0051165	2,5-dihydroxypyridine metabolic process
	is_a	GO:0072524	WAS	GO:0072524;GO:1901615
biological_process	GO:0051166	2,5-dihydroxypyridine catabolic process
	is_a	GO:0051165;GO:0072526	WAS	GO:0051165;GO:0072526;GO:1901616
biological_process	GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity
	is_a	GO:0051345	WAS	GO:0051342;GO:0051345
biological_process	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity
	is_a	GO:0051346	WAS	GO:0051342;GO:0051346
biological_process	GO:0051349	positive regulation of lyase activity
	is_a	GO:0043085	WAS	GO:0043085;GO:0051339
biological_process	GO:0051350	negative regulation of lyase activity
	is_a	GO:0043086	WAS	GO:0043086;GO:0051339
biological_process	GO:0051351	positive regulation of ligase activity
	is_a	GO:0043085	WAS	GO:0043085;GO:0051340
biological_process	GO:0051554	flavonol metabolic process
	is_a	GO:0051552	WAS	GO:0051552;GO:1901615
biological_process	GO:0051555	flavonol biosynthetic process
	is_a	GO:0051553;GO:0051554	WAS	GO:0051553;GO:0051554;GO:1901617
biological_process	GO:0051556	leucoanthocyanidin metabolic process
	is_a	GO:0009698;GO:0009812	WAS	GO:0009698;GO:0009812;GO:1901615
biological_process	GO:0051557	leucoanthocyanidin biosynthetic process
	is_a	GO:0009699;GO:0009813;GO:0051556	WAS	GO:0009699;GO:0009813;GO:0051556;GO:1901617
biological_process	GO:0051593	response to folic acid
	is_a	GO:0033273;GO:1901698;GO:1901700	WAS	GO:0014070;GO:0033273;GO:1901698;GO:1901700
biological_process	GO:0051607	defense response to virus
	is_a	GO:0009615;GO:0098542	WAS	GO:0009615;GO:0140546
biological_process	GO:0051851	host-mediated perturbation of symbiont process
	is_a	GO:0035821	WAS	GO:0051702
biological_process	GO:0052003	symbiont-mediated suppression of defense-related host salicylic acid-mediated signal transduction pathway
	is_a	GO:0052081	WAS	GO:0009968;GO:0010113;GO:0044414;GO:0052081;GO:0052089
	relationship	negatively_regulates GO:0009627;negatively_regulates GO:0009862	WAS	negatively_regulates GO:0009862
biological_process	GO:0052026	symbiont-mediated perturbation of host transcription
	is_a	GO:0039656	WAS	GO:0044068
biological_process	GO:0052032	symbiont-mediated perturbation of host inflammatory response
	is_a	GO:0052167	WAS	GO:0052031
biological_process	GO:0052036	symbiont-mediated suppression of host inflammatory response
	is_a	GO:0052032	WAS	GO:0044414;GO:0052032
biological_process	GO:0052041	symbiont-mediated suppression of host programmed cell death
	is_a	GO:0052040	WAS	GO:0044003
biological_process	GO:0052042	symbiont-mediated activation of host programmed cell death
	is_a	GO:0052040	WAS	GO:0044003
	relationship	N/A	WAS	part_of GO:0001907
biological_process	GO:0052081	symbiont-mediated perturbation of host salicylic acid-mediated signal transduction pathway
	is_a	GO:0052027	WAS	GO:0052027;GO:0052031
biological_process	GO:0052088	symbiont-mediated perturbation of host jasmonic acid signaling
	is_a	GO:0052027;GO:0052167	WAS	GO:0042783
biological_process	GO:0052091	modulation of nutrient release by host
	is_a	GO:0044002	WAS	GO:0044003
	relationship	N/A	WAS	part_of GO:0044002
biological_process	GO:0052158	symbiont-mediated perturbation of host resistance gene-dependent defense response
	is_a	GO:0030682;GO:0052167	WAS	GO:0075136
biological_process	GO:0052160	symbiont-mediated perturbation of host systemic acquired resistance
	is_a	GO:0052031	WAS	GO:0044003
biological_process	GO:0052167	symbiont-mediated perturbation of host innate immune response
	is_a	GO:0052553	WAS	GO:0052031;GO:0052553
biological_process	GO:0052170	symbiont-mediated suppression of host innate immune response
	is_a	GO:0052167;GO:0052562	WAS	GO:0044414;GO:0052167;GO:0052562
biological_process	GO:0052200	symbiont-mediated response to host defenses
	is_a	GO:0075136	WAS	GO:0052173;GO:0075136
biological_process	GO:0052322	positive regulation of phytoalexin biosynthetic process
	is_a	GO:0140546;GO:1900378	WAS	GO:0052319;GO:0052320;GO:1900378
biological_process	GO:0052553	symbiont-mediated perturbation of host immune response
	is_a	GO:0052031	WAS	GO:0044003
biological_process	GO:0052562	symbiont-mediated suppression of host immune response
	is_a	GO:0052553	WAS	GO:0044003
biological_process	GO:0052776	chitin catabolic process to fructose 6-phosphate via glucosamine
	is_a	GO:0006032;GO:0006083;GO:0006796;GO:0019637	WAS	GO:0006041;GO:0006083;GO:0052777
biological_process	GO:0060141	symbiont-mediated induction of syncytium formation
	is_a	GO:0044068	WAS	GO:0044003
biological_process	GO:0060192	negative regulation of lipase activity
	is_a	GO:0051346	WAS	GO:0051346;GO:0060191
biological_process	GO:0060193	positive regulation of lipase activity
	is_a	GO:0051345	WAS	GO:0051345;GO:0060191
biological_process	GO:0060550	positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity
	is_a	GO:0010922	WAS	GO:0010922;GO:0060549
biological_process	GO:0060558	regulation of calcidiol 1-monooxygenase activity
	is_a	GO:0051341	WAS	GO:0032768
biological_process	GO:0060585	positive regulation of prostaglandin-endoperoxide synthase activity
	is_a	GO:0051353	WAS	GO:0051353;GO:0060584
biological_process	GO:0060695	negative regulation of cholesterol transporter activity
	is_a	GO:0110114	WAS	GO:0060694;GO:0110114
biological_process	GO:0060700	regulation of ribonuclease activity
	is_a	GO:0051252;GO:0051336	WAS	GO:0032069;GO:0051252
biological_process	GO:0060702	negative regulation of endoribonuclease activity
	is_a	GO:0032074;GO:0060699	WAS	GO:0060699;GO:0060701
biological_process	GO:0061370	testosterone biosynthetic process
	is_a	GO:0006694;GO:0042181;GO:0120255	WAS	GO:0006694;GO:0042181;GO:0120255;GO:1901617
biological_process	GO:0062003	negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity
	is_a	GO:0051346;GO:0062014	WAS	GO:0051346;GO:0062002;GO:0062014
biological_process	GO:0062173	brexanolone metabolic process
	is_a	GO:0008202;GO:0042180	WAS	GO:0008202;GO:0042180;GO:1901615
biological_process	GO:0062174	brexanolone biosynthetic process
	is_a	GO:0006694;GO:0042181;GO:0062173	WAS	GO:0006694;GO:0042181;GO:0062173;GO:1901617
biological_process	GO:0062175	brexanolone catabolic process
	is_a	GO:0006706;GO:0042182;GO:0062173	WAS	GO:0006706;GO:0042182;GO:0062173;GO:1901616
biological_process	GO:0070781	response to biotin
	is_a	GO:0033273;GO:1901698;GO:1901700	WAS	GO:0014070;GO:0033273;GO:1901698;GO:1901700
biological_process	GO:0071231	cellular response to folic acid
	is_a	GO:0051593;GO:0071295;GO:1901699;GO:1901701	WAS	GO:0051593;GO:0071295;GO:0071407;GO:1901699;GO:1901701
biological_process	GO:0071232	cellular response to histidine
	is_a	GO:0071230;GO:0080052;GO:1901699;GO:1901701	WAS	GO:0071230;GO:0071407;GO:0080052;GO:1901699;GO:1901701
biological_process	GO:0071234	cellular response to phenylalanine
	is_a	GO:0071230;GO:0080053;GO:1901699;GO:1901701	WAS	GO:0071230;GO:0071407;GO:0080053;GO:1901699;GO:1901701
biological_process	GO:0071235	cellular response to proline
	is_a	GO:0010238;GO:0071230;GO:1901699;GO:1901701	WAS	GO:0010238;GO:0071230;GO:0071407;GO:1901699;GO:1901701
biological_process	GO:0071238	cellular response to brefeldin A
	is_a	GO:0031001;GO:0071236;GO:1901701	WAS	GO:0031001;GO:0071236;GO:0071407;GO:1901701
biological_process	GO:0071272	morphine metabolic process
	is_a	GO:0033076	WAS	GO:0033076;GO:1901376
biological_process	GO:0071273	morphine catabolic process
	is_a	GO:0071272;GO:0071274	WAS	GO:0071272;GO:0071274;GO:1901377
biological_process	GO:0071296	cellular response to biotin
	is_a	GO:0070781;GO:0071295;GO:1901699;GO:1901701	WAS	GO:0070781;GO:0071295;GO:0071407;GO:1901699;GO:1901701
biological_process	GO:0071297	cellular response to cobalamin
	is_a	GO:0033590;GO:0071295;GO:1901699;GO:1901701	WAS	GO:0033590;GO:0071295;GO:0071407;GO:1901699;GO:1901701
biological_process	GO:0071298	cellular response to L-ascorbic acid
	is_a	GO:0033591;GO:0071295;GO:0071326	WAS	GO:0033591;GO:0071295;GO:0071326;GO:0071407
biological_process	GO:0071301	cellular response to vitamin B1
	is_a	GO:0010266;GO:0071295;GO:0097306;GO:1901699	WAS	GO:0010266;GO:0071295;GO:0071407;GO:0097306;GO:1901699
biological_process	GO:0071302	cellular response to vitamin B2
	is_a	GO:0033274;GO:0071295;GO:1901699;GO:1901701	WAS	GO:0033274;GO:0071295;GO:0071407;GO:1901699;GO:1901701
biological_process	GO:0071304	cellular response to vitamin B6
	is_a	GO:0034516;GO:0071295;GO:1901699;GO:1901701	WAS	GO:0034516;GO:0071295;GO:0071407;GO:1901699;GO:1901701
biological_process	GO:0071305	cellular response to vitamin D
	is_a	GO:0033280;GO:0071295;GO:0071396;GO:1901701	WAS	GO:0033280;GO:0071295;GO:0071396;GO:0071407;GO:1901701
biological_process	GO:0071306	cellular response to vitamin E
	is_a	GO:0033197;GO:0071295;GO:1901701	WAS	GO:0033197;GO:0071295;GO:0071407;GO:1901701
biological_process	GO:0071314	cellular response to cocaine
	is_a	GO:0042220;GO:0071312;GO:1901701	WAS	GO:0042220;GO:0071312;GO:0071407;GO:1901701
biological_process	GO:0071317	cellular response to isoquinoline alkaloid
	is_a	GO:0014072;GO:0071312	WAS	GO:0014072;GO:0071312;GO:0071407
biological_process	GO:0071318	cellular response to ATP
	is_a	GO:0033198;GO:1901699;GO:1901701	WAS	GO:0033198;GO:0071407;GO:1901699;GO:1901701
biological_process	GO:0071319	cellular response to benzoic acid
	is_a	GO:0080021;GO:1901701	WAS	GO:0071407;GO:0080021;GO:1901701
biological_process	GO:0071320	cellular response to cAMP
	is_a	GO:0051591;GO:1901699;GO:1901701	WAS	GO:0051591;GO:0071407;GO:1901699;GO:1901701
biological_process	GO:0071321	cellular response to cGMP
	is_a	GO:0070305;GO:1901699;GO:1901701	WAS	GO:0070305;GO:0071407;GO:1901699;GO:1901701
biological_process	GO:0071359	cellular response to dsRNA
	is_a	GO:0043331;GO:1901699	WAS	GO:0043331;GO:0071407;GO:1901699
biological_process	GO:0071366	cellular response to indolebutyric acid stimulus
	is_a	GO:0071365;GO:0080026;GO:1901699;GO:1901701	WAS	GO:0071365;GO:0071407;GO:0080026;GO:1901699;GO:1901701
biological_process	GO:0071367	cellular response to brassinosteroid stimulus
	is_a	GO:0009741;GO:0032870;GO:0071396;GO:1901701	WAS	GO:0009741;GO:0032870;GO:0071396;GO:0071407;GO:1901701
biological_process	GO:0071382	cellular response to prostaglandin I stimulus
	is_a	GO:0034697;GO:0071379;GO:1901701	WAS	GO:0034697;GO:0071379;GO:0071407;GO:1901701
biological_process	GO:0071383	cellular response to steroid hormone stimulus
	is_a	GO:0032870;GO:0048545;GO:0071396	WAS	GO:0032870;GO:0048545;GO:0071396;GO:0071407
biological_process	GO:0071392	cellular response to estradiol stimulus
	is_a	GO:0032355;GO:0071396;GO:1901701	WAS	GO:0032355;GO:0071396;GO:0071407;GO:1901701
biological_process	GO:0071394	cellular response to testosterone stimulus
	is_a	GO:0033574;GO:0071396;GO:1901655	WAS	GO:0033574;GO:0071396;GO:0071407;GO:1901655
biological_process	GO:0071408	cellular response to cycloalkane
	is_a	GO:0014071;GO:0070887	WAS	GO:0014071;GO:0071407
biological_process	GO:0071409	cellular response to cycloheximide
	is_a	GO:0046898;GO:0097306;GO:1901655;GO:1901699	WAS	GO:0046898;GO:0071407;GO:0097306;GO:1901655;GO:1901699
biological_process	GO:0071410	cellular response to cyclopentenone
	is_a	GO:0010583	WAS	GO:0010583;GO:0071407
biological_process	GO:0071414	cellular response to methotrexate
	is_a	GO:0031427;GO:1901699;GO:1901701	WAS	GO:0031427;GO:0071407;GO:1901699;GO:1901701
biological_process	GO:0071415	cellular response to purine-containing compound
	is_a	GO:0014074	WAS	GO:0014074;GO:0071407;GO:1901699
biological_process	GO:0071416	cellular response to tropane
	is_a	GO:0014073;GO:0071312	WAS	GO:0014073;GO:0071312;GO:0071407
biological_process	GO:0071420	cellular response to histamine
	is_a	GO:0034776;GO:1901699	WAS	GO:0034776;GO:0071407;GO:1901699
biological_process	GO:0071446	cellular response to salicylic acid stimulus
	is_a	GO:0009751;GO:1901701	WAS	GO:0009751;GO:0071407;GO:1901701
biological_process	GO:0071505	response to mycophenolic acid
	is_a	GO:1901700	WAS	GO:0014070;GO:1901700
biological_process	GO:0071506	cellular response to mycophenolic acid
	is_a	GO:0071505;GO:1901701	WAS	GO:0071407;GO:0071505;GO:1901701
biological_process	GO:0071680	response to indole-3-methanol
	is_a	GO:0097305;GO:1901698	WAS	GO:0014070;GO:0097305;GO:1901698
biological_process	GO:0071681	cellular response to indole-3-methanol
	is_a	GO:0071680;GO:0097306;GO:1901699	WAS	GO:0071407;GO:0071680;GO:0097306;GO:1901699
biological_process	GO:0071869	response to catecholamine
	is_a	GO:0071867;GO:1901700	WAS	GO:0014070;GO:0071867;GO:1901700
biological_process	GO:0071870	cellular response to catecholamine stimulus
	is_a	GO:0071868;GO:0071869;GO:1901701	WAS	GO:0071407;GO:0071868;GO:0071869;GO:1901701
biological_process	GO:0072712	response to thiabendazole
	is_a	GO:1901698	WAS	GO:0014070;GO:1901698
biological_process	GO:0072713	cellular response to thiabendazole
	is_a	GO:0072712;GO:1901699	WAS	GO:0071407;GO:0072712;GO:1901699
biological_process	GO:0072722	response to amitrole
	is_a	GO:1901698	WAS	GO:0014070;GO:1901698
biological_process	GO:0072723	cellular response to amitrole
	is_a	GO:0072722;GO:1901699	WAS	GO:0071407;GO:0072722;GO:1901699
biological_process	GO:0072724	response to 4-nitroquinoline N-oxide
	is_a	GO:1901698;GO:1901700	WAS	GO:0014070;GO:1901698;GO:1901700
biological_process	GO:0072725	cellular response to 4-nitroquinoline N-oxide
	is_a	GO:0072724;GO:1901699;GO:1901701	WAS	GO:0071407;GO:0072724;GO:1901699;GO:1901701
biological_process	GO:0072730	response to papulacandin B
	is_a	GO:0033993;GO:1901700	WAS	GO:0014070;GO:0033993;GO:1901700
biological_process	GO:0072731	cellular response to papulacandin B
	is_a	GO:0071396;GO:0072730;GO:1901701	WAS	GO:0071396;GO:0071407;GO:0072730;GO:1901701
biological_process	GO:0072733	response to staurosporine
	is_a	GO:0043279	WAS	GO:0014070;GO:0043279
biological_process	GO:0072734	cellular response to staurosporine
	is_a	GO:0071312;GO:0072733	WAS	GO:0071312;GO:0071407;GO:0072733
biological_process	GO:0072743	cellular response to erythromycin
	is_a	GO:1901323;GO:1901701	WAS	GO:0071407;GO:1901323;GO:1901701
biological_process	GO:0072744	cellular response to trichodermin
	is_a	GO:0071362;GO:1901324	WAS	GO:0071362;GO:0071407;GO:1901324
biological_process	GO:0072745	cellular response to antimycin A
	is_a	GO:1901325;GO:1901699;GO:1901701	WAS	GO:0071407;GO:1901325;GO:1901699;GO:1901701
biological_process	GO:0072748	cellular response to tacrolimus
	is_a	GO:1901327;GO:1901699;GO:1901701	WAS	GO:0071407;GO:1901327;GO:1901699;GO:1901701
biological_process	GO:0072749	cellular response to cytochalasin B
	is_a	GO:1901328;GO:1901699;GO:1901701	WAS	GO:0071407;GO:1901328;GO:1901699;GO:1901701
biological_process	GO:0072750	cellular response to leptomycin B
	is_a	GO:0071398;GO:1901344	WAS	GO:0071398;GO:0071407;GO:1901344
biological_process	GO:0072752	cellular response to rapamycin
	is_a	GO:0071362;GO:0097306;GO:1901355;GO:1901655;GO:1901699	WAS	GO:0071362;GO:0071407;GO:0097306;GO:1901355;GO:1901655;GO:1901699
biological_process	GO:0072754	cellular response to purvalanol A
	is_a	GO:0071415;GO:1901560;GO:1901699	WAS	GO:0071415;GO:1901560
biological_process	GO:0072757	cellular response to camptothecin
	is_a	GO:0071312;GO:0097306;GO:1901563	WAS	GO:0071312;GO:0071407;GO:0097306;GO:1901563
biological_process	GO:0072761	cellular response to capsazepine
	is_a	GO:1901594	WAS	GO:0071407;GO:1901594;GO:1901699;GO:1901701
biological_process	GO:0072762	cellular response to carbendazim
	is_a	GO:1901597	WAS	GO:0071407;GO:1901597;GO:1901699;GO:1901701
biological_process	GO:0072763	cellular response to hesperadin
	is_a	GO:0071418;GO:1901595;GO:1901701	WAS	GO:0071407;GO:0071418;GO:1901595;GO:1901701
biological_process	GO:0072764	cellular response to reversine
	is_a	GO:0071415;GO:1901596	WAS	GO:0071415;GO:1901596;GO:1901701
biological_process	GO:0075509	endocytosis involved in viral entry into host cell
	is_a	GO:0046718	WAS	GO:0006897;GO:0046794
	relationship	N/A	WAS	part_of GO:0046718
	intersection_of	N/A	WAS	is_a GO:0006897;part_of GO:0046718
biological_process	GO:0075733	intracellular transport of virus
	is_a	GO:0044403;GO:0046794	WAS	GO:0046794
biological_process	GO:0080021	response to benzoic acid
	is_a	GO:1901700	WAS	GO:0014070;GO:1901700
biological_process	GO:0080026	response to indolebutyric acid
	is_a	GO:0009733;GO:1901698;GO:1901700	WAS	GO:0009733;GO:0014070;GO:1901698;GO:1901700
biological_process	GO:0080052	response to histidine
	is_a	GO:0043200;GO:1901698;GO:1901700	WAS	GO:0014070;GO:0043200;GO:1901698;GO:1901700
biological_process	GO:0080053	response to phenylalanine
	is_a	GO:0043200;GO:1901698;GO:1901700	WAS	GO:0014070;GO:0043200;GO:1901698;GO:1901700
biological_process	GO:0080184	response to phenylpropanoid
	is_a	GO:0042221	WAS	GO:0014070
biological_process	GO:0080185	effector-mediated activation of plant hypersensitive response by symbiont
	is_a	GO:0034055;GO:0052158	WAS	GO:0052042;GO:0052158;GO:0140404
biological_process	GO:0090120	lysosome to ER cholesterol transport
	is_a	GO:0007041;GO:0016192;GO:0032367	WAS	GO:0007041;GO:0090119
biological_process	GO:0090398	cellular senescence
	is_a	GO:0009987	WAS	GO:0008152
biological_process	GO:0090399	replicative senescence
	is_a	GO:0022402	WAS	GO:0008152
biological_process	GO:0090727	positive regulation of brood size
	is_a	GO:0065007	WAS	GO:0060378
biological_process	GO:0090728	negative regulation of brood size
	is_a	GO:0065007	WAS	GO:0060378
biological_process	GO:0097068	response to thyroxine
	is_a	GO:0043200;GO:0097066;GO:1901700;GO:1904386	WAS	GO:0014070;GO:0043200;GO:0097066;GO:1901700;GO:1904386
biological_process	GO:0097069	cellular response to thyroxine stimulus
	is_a	GO:0071230;GO:0097067;GO:0097068;GO:1901701;GO:1904387	WAS	GO:0071230;GO:0071407;GO:0097067;GO:0097068;GO:1901701;GO:1904387
biological_process	GO:0097250	mitochondrial respirasome assembly
	is_a	GO:0007005;GO:0033108	WAS	GO:0007005;GO:0065003
	relationship	N/A	WAS	occurs_in GO:0005739
biological_process	GO:0097251	leukotriene B4 biosynthetic process
	is_a	GO:0019370;GO:0036102;GO:0042759;GO:1901570	WAS	GO:0019370;GO:0036102;GO:0042759;GO:1901570;GO:1901617
biological_process	GO:0097295	morphine biosynthetic process
	is_a	GO:0033075;GO:0071272	WAS	GO:0033075;GO:0071272;GO:1901378
biological_process	GO:0097330	response to 5-fluoro-2'-deoxyuridine
	is_a	GO:1901698;GO:1901700	WAS	GO:0014070;GO:1901698;GO:1901700
biological_process	GO:0097331	response to cytarabine
	is_a	GO:1901698;GO:1903416	WAS	GO:0014070;GO:1901698;GO:1903416
biological_process	GO:0097333	response to olanzapine
	is_a	GO:1901698	WAS	GO:0014070;GO:1901698
biological_process	GO:0097334	response to perphenazine
	is_a	GO:0097305;GO:1901698	WAS	GO:0014070;GO:0097305;GO:1901698
biological_process	GO:0097335	response to quetiapine
	is_a	GO:1901698	WAS	GO:0014070;GO:1901698
biological_process	GO:0097336	response to risperidone
	is_a	GO:1901698;GO:1901700	WAS	GO:0014070;GO:1901698;GO:1901700
biological_process	GO:0097337	response to ziprasidone
	is_a	GO:1901698	WAS	GO:0014070;GO:1901698
biological_process	GO:0097338	response to clozapine
	is_a	GO:1901698	WAS	GO:0014070;GO:1901698
biological_process	GO:0098673	symbiont-mediated suppression of host DNA replication
	is_a	GO:0044068	WAS	GO:0044003
biological_process	GO:0098968	neurotransmitter receptor transport postsynaptic membrane to endosome
	is_a	GO:0016192;GO:0097120	WAS	GO:0016192;GO:0062237;GO:0072594;GO:0097120;GO:0099637;GO:1902946
biological_process	GO:0099015	degradation of host chromosome by virus
	is_a	GO:0016032	WAS	GO:0039637
	relationship	part_of GO:0039693	WAS	N/A
biological_process	GO:0110113	positive regulation of lipid transporter activity
	is_a	GO:0032370;GO:0032411	WAS	GO:0032370;GO:0032411;GO:0110112
biological_process	GO:0110114	negative regulation of lipid transporter activity
	is_a	GO:0032369;GO:0032410	WAS	GO:0032369;GO:0032410;GO:0110112
biological_process	GO:0140321	symbiont-mediated suppression of host autophagy
	is_a	GO:0075071	WAS	GO:0044003
biological_process	GO:0140415	effector-mediated perturbation of host defenses by symbiont
	is_a	GO:0052031;GO:0052200;GO:0140418	WAS	GO:0052200;GO:0140418
biological_process	GO:0140446	fumigermin biosynthetic process
	is_a	GO:0030639;GO:1901336	WAS	GO:0030639;GO:1901336;GO:1901617
biological_process	GO:0140502	effector-mediated suppression of host salicylic acid-mediated innate immune signaling
	is_a	GO:0052003;GO:0052029;GO:0140404	WAS	GO:0052003;GO:0140404
biological_process	GO:0140590	effector-mediated suppression of host defense response
	is_a	GO:0140415	WAS	GO:0044414;GO:0140415
biological_process	GO:0140754	reorganization of cellular membranes to establish viral sites of replication
	is_a	GO:0141171	WAS	GO:0051702
biological_process	GO:0140755	reorganization of host cellular membranes to establish sites of replication
	is_a	GO:0016032;GO:0141171	WAS	GO:0019054
biological_process	GO:0140876	andrastin A biosynthetic process
	is_a	GO:0006694;GO:0042181;GO:0043386;GO:0046184;GO:0120255;GO:1900620	WAS	GO:0006694;GO:0042181;GO:0043386;GO:0046184;GO:0120255;GO:1900620;GO:1901617
biological_process	GO:0140883	symbiont-mediated activation of host reticulophagy
	is_a	GO:0039520	WAS	GO:0044068;GO:0141088
biological_process	GO:0140976	host defense response against symbiont-mediated perturbation of plasma membrane integrity
	is_a	GO:0140546	WAS	GO:0098542
biological_process	GO:0141023	symbiont-mediated disruption of host cell-cell adhesion
	is_a	GO:0044068	WAS	GO:0044003
biological_process	GO:0141073	symbiont-mediated perturbation of host opsonization
	is_a	GO:0052031	WAS	GO:0044003
biological_process	GO:0141083	symbiont-mediated suppression of host reactive oxygen species generation
	is_a	GO:0044068;GO:0052031	WAS	GO:0044003
biological_process	GO:0141145	symbiont-mediated suppression of host neutrophil extracellular trap formation
	is_a	GO:0044068;GO:0052031	WAS	GO:0044068
biological_process	GO:0141154	symbiont-mediated suppression of host-directed shutoff of host translation
	is_a	GO:0044414	WAS	GO:0019057
biological_process	GO:0141155	symbiont-mediated suppression of host translation elongation
	is_a	GO:0039656	WAS	GO:0044003
biological_process	GO:0141157	symbiont-mediated suppression of host exocytosis
	is_a	GO:1990215	WAS	GO:0044003
biological_process	GO:0141158	symbiont-mediated suppression of host phagosome maturation
	is_a	GO:0044068	WAS	GO:0044003
biological_process	GO:0141159	symbiont-mediated suppression of host phagosome acidification
	is_a	GO:0052031	WAS	GO:0044003
biological_process	GO:0141204	dipeptide transmembrane transport from lysosomal lumen to cytosol
	is_a	GO:0015833;GO:0170063	WAS	GO:0007041;GO:0015833;GO:0034486
biological_process	GO:0150072	positive regulation of arginase activity
	is_a	GO:0051345	WAS	GO:0051345;GO:0150070
biological_process	GO:0150074	positive regulation of protein-glutamine gamma-glutamyltransferase activity
	is_a	GO:0051347	WAS	GO:0051347;GO:0150073
biological_process	GO:1900003	regulation of serine-type endopeptidase activity
	is_a	GO:0052548	WAS	GO:0052548;GO:1902571
biological_process	GO:1900005	positive regulation of serine-type endopeptidase activity
	is_a	GO:0010950;GO:1900003	WAS	GO:0010950;GO:1900003;GO:1902573
biological_process	GO:1900011	negative regulation of corticotropin-releasing hormone receptor activity
	is_a	GO:0009968;GO:2000272	WAS	GO:0009968;GO:1900010;GO:2000272
biological_process	GO:1900131	negative regulation of lipid binding
	is_a	GO:0051100	WAS	GO:0051100;GO:1900130
biological_process	GO:1900163	positive regulation of phospholipid scramblase activity
	is_a	GO:0110113	WAS	GO:0110113;GO:1900161
biological_process	GO:1900260	negative regulation of RNA-dependent RNA polymerase activity
	is_a	GO:0051348	WAS	GO:0051348;GO:1900259
biological_process	GO:1900264	positive regulation of DNA-directed DNA polymerase activity
	is_a	GO:0051347;GO:2000573	WAS	GO:0051347;GO:1900262;GO:2000573
biological_process	GO:1900609	F-9775A metabolic process
	is_a	GO:0018958;GO:0030638	WAS	GO:0018958;GO:0030638;GO:1901376
biological_process	GO:1900610	F-9775A catabolic process
	is_a	GO:0019336;GO:0030640;GO:1900609	WAS	GO:0019336;GO:0030640;GO:1900609;GO:1901377
biological_process	GO:1900611	F-9775A biosynthetic process
	is_a	GO:0030639;GO:0046189;GO:1900609	WAS	GO:0030639;GO:0046189;GO:1900609;GO:1901378
biological_process	GO:1900612	F-9775B metabolic process
	is_a	GO:0018958;GO:0030638	WAS	GO:0018958;GO:0030638;GO:1901376
biological_process	GO:1900613	F-9775B catabolic process
	is_a	GO:0019336;GO:0030640;GO:1900612	WAS	GO:0019336;GO:0030640;GO:1900612;GO:1901377
biological_process	GO:1900614	F-9775B biosynthetic process
	is_a	GO:0030639;GO:0046189;GO:1900612	WAS	GO:0030639;GO:0046189;GO:1900612;GO:1901378
biological_process	GO:1900772	fumitremorgin B biosynthetic process
	is_a	GO:0035835	WAS	GO:0035835;GO:1901378
biological_process	GO:1900796	terrequinone A biosynthetic process
	is_a	GO:0009821;GO:0120255;GO:1901663	WAS	GO:0009821;GO:0120255;GO:1901617;GO:1901663
biological_process	GO:1900983	vindoline metabolic process
	is_a	GO:0046447;GO:1900619;GO:1902644	WAS	GO:0046447;GO:1900619;GO:1901376;GO:1902644
biological_process	GO:1900985	vindoline biosynthetic process
	is_a	GO:0009709;GO:1900620;GO:1900983;GO:1902645	WAS	GO:0009709;GO:1900620;GO:1900983;GO:1901378;GO:1902645
biological_process	GO:1900988	ajmaline biosynthetic process
	is_a	GO:0009709	WAS	GO:0009709;GO:1901617
biological_process	GO:1901012	(S)-reticuline biosynthetic process
	is_a	GO:0009708	WAS	GO:0009708;GO:1901617
biological_process	GO:1901183	positive regulation of camalexin biosynthetic process
	is_a	GO:0051176;GO:0052322	WAS	GO:0051176;GO:0052322;GO:1901182
biological_process	GO:1901252	regulation of intracellular transport of viral material
	is_a	GO:0043903;GO:1903900	WAS	GO:1903900
biological_process	GO:1901323	response to erythromycin
	is_a	GO:1901700	WAS	GO:0014070;GO:1901700
biological_process	GO:1901324	response to trichodermin
	is_a	GO:0045472	WAS	GO:0014070;GO:0045472
biological_process	GO:1901325	response to antimycin A
	is_a	GO:1901698;GO:1901700	WAS	GO:0014070;GO:1901698;GO:1901700
biological_process	GO:1901327	response to tacrolimus
	is_a	GO:1901698;GO:1901700	WAS	GO:0014070;GO:1901698;GO:1901700
biological_process	GO:1901328	response to cytochalasin B
	is_a	GO:1901698;GO:1901700	WAS	GO:0014070;GO:1901698;GO:1901700
biological_process	GO:1901344	response to leptomycin B
	is_a	GO:0070542	WAS	GO:0014070;GO:0070542
biological_process	GO:1901355	response to rapamycin
	is_a	GO:0045472;GO:0097305;GO:1901654;GO:1901698	WAS	GO:0014070;GO:0045472;GO:0097305;GO:1901654;GO:1901698
biological_process	GO:1901423	response to benzene
	is_a	GO:0042221	WAS	GO:0014070
biological_process	GO:1901424	response to toluene
	is_a	GO:0042221	WAS	GO:0014070
biological_process	GO:1901426	response to furfural
	is_a	GO:1901700	WAS	GO:0014070;GO:1901700
biological_process	GO:1901493	response to decalin
	is_a	GO:0042221	WAS	GO:0014070
biological_process	GO:1901497	response to diphenyl ether
	is_a	GO:0045472	WAS	GO:0014070;GO:0045472
biological_process	GO:1901498	response to tetralin
	is_a	GO:0042221	WAS	GO:0014070
biological_process	GO:1901501	response to xylene
	is_a	GO:0042221	WAS	GO:0014070
biological_process	GO:1901554	response to paracetamol
	is_a	GO:1901698;GO:1901700	WAS	GO:0014070;GO:1901698;GO:1901700
biological_process	GO:1901556	response to candesartan
	is_a	GO:1901698;GO:1901700	WAS	GO:0014070;GO:1901698;GO:1901700
biological_process	GO:1901557	response to fenofibrate
	is_a	GO:0045472;GO:1901654	WAS	GO:0014070;GO:0045472;GO:1901654
biological_process	GO:1901559	response to ribavirin
	is_a	GO:1901698;GO:1901700	WAS	GO:0014070;GO:1901698;GO:1901700
biological_process	GO:1901563	response to camptothecin
	is_a	GO:0043279;GO:0097305	WAS	GO:0014070;GO:0043279;GO:0097305
biological_process	GO:1901594	response to capsazepine
	is_a	GO:1901698;GO:1901700	WAS	GO:0014070;GO:1901698;GO:1901700
biological_process	GO:1901595	response to hesperadin
	is_a	GO:0014075;GO:1901700	WAS	GO:0014070;GO:0014075;GO:1901700
biological_process	GO:1901597	response to carbendazim
	is_a	GO:1901698;GO:1901700	WAS	GO:0014070;GO:1901698;GO:1901700
biological_process	GO:1901666	positive regulation of NAD+ ADP-ribosyltransferase activity
	is_a	GO:0010835;GO:0051347	WAS	GO:0051347;GO:1901664
biological_process	GO:1901732	quercetin metabolic process
	is_a	GO:0051552	WAS	GO:0051552;GO:1901615
biological_process	GO:1901733	quercetin catabolic process
	is_a	GO:0046275;GO:1901732	WAS	GO:0046275;GO:1901616;GO:1901732
biological_process	GO:1901734	quercetin biosynthetic process
	is_a	GO:0051553;GO:1901732	WAS	GO:0051553;GO:1901617;GO:1901732
biological_process	GO:1901735	(R)-mevalonic acid metabolic process
	is_a	GO:0032787	WAS	GO:0032787;GO:1901615
biological_process	GO:1901736	(R)-mevalonic acid catabolic process
	is_a	GO:0072329;GO:1901735	WAS	GO:0072329;GO:1901616;GO:1901735
biological_process	GO:1901737	(R)-mevalonic acid biosynthetic process
	is_a	GO:0072330;GO:1901735	WAS	GO:0072330;GO:1901617;GO:1901735
biological_process	GO:1901824	alpha-carotene biosynthetic process
	is_a	GO:0016117;GO:0016120	WAS	GO:0016117;GO:0016120;GO:1901822
biological_process	GO:1901905	response to tamsulosin
	is_a	GO:0014075;GO:0045472	WAS	GO:0014070;GO:0014075;GO:0045472
biological_process	GO:1901919	positive regulation of exoribonuclease activity
	is_a	GO:0032075;GO:0060700	WAS	GO:1901917;GO:1905779
biological_process	GO:1901986	response to ketamine
	is_a	GO:1901654;GO:1901698	WAS	GO:0014070;GO:1901654;GO:1901698
biological_process	GO:1902171	regulation of tocopherol cyclase activity
	is_a	GO:0050790	WAS	GO:0031279
biological_process	GO:1902280	regulation of RNA helicase activity
	is_a	GO:0043462;GO:0050790	WAS	GO:0051095
biological_process	GO:1902347	response to strigolactone
	is_a	GO:0033993;GO:1901700	WAS	GO:0014070;GO:0033993;GO:1901700
biological_process	GO:1902348	cellular response to strigolactone
	is_a	GO:0071396;GO:1901701;GO:1902347	WAS	GO:0071396;GO:0071407;GO:1901701;GO:1902347
biological_process	GO:1902349	response to chloroquine
	is_a	GO:1901698	WAS	GO:0014070;GO:1901698
biological_process	GO:1902350	cellular response to chloroquine
	is_a	GO:1901699;GO:1902349	WAS	GO:0071407;GO:1901699;GO:1902349
biological_process	GO:1902351	response to imidacloprid
	is_a	GO:1901698	WAS	GO:0014070;GO:1901698
biological_process	GO:1902384	glycyrrhetinate metabolic process
	is_a	GO:0019742;GO:0032787;GO:0042180	WAS	GO:0019742;GO:0032787;GO:0042180;GO:1901615
biological_process	GO:1902385	glycyrrhetinate catabolic process
	is_a	GO:0019741;GO:0042182;GO:0072329;GO:1902384	WAS	GO:0019741;GO:0042182;GO:0072329;GO:1901616;GO:1902384
biological_process	GO:1902386	glycyrrhetinate biosynthetic process
	is_a	GO:0019745;GO:0042181;GO:0072330;GO:1902384	WAS	GO:0019745;GO:0042181;GO:0072330;GO:1901617;GO:1902384
biological_process	GO:1902415	regulation of mRNA binding
	is_a	GO:0051098	WAS	GO:1905214
biological_process	GO:1902520	response to doxorubicin
	is_a	GO:0097305;GO:1901654;GO:1901698;GO:1903416	WAS	GO:0014070;GO:0097305;GO:1901654;GO:1901698;GO:1903416
biological_process	GO:1902521	response to etoposide
	is_a	GO:1904631	WAS	GO:0014070;GO:1904631
biological_process	GO:1902551	regulation of catalase activity
	is_a	GO:0051341	WAS	GO:2000468
biological_process	GO:1902572	negative regulation of serine-type peptidase activity
	is_a	GO:0010466	WAS	GO:0010466;GO:1902571
biological_process	GO:1902596	negative regulation of DNA replication origin binding
	is_a	GO:0043392	WAS	GO:0043392;GO:1902595
biological_process	GO:1902597	positive regulation of DNA replication origin binding
	is_a	GO:0043388	WAS	GO:0043388;GO:1902595
biological_process	GO:1902607	negative regulation of large conductance calcium-activated potassium channel activity
	is_a	GO:1901017;GO:2001258	WAS	GO:1901017;GO:1902606;GO:2001258
biological_process	GO:1902608	positive regulation of large conductance calcium-activated potassium channel activity
	is_a	GO:1901018;GO:2001259	WAS	GO:1901018;GO:1902606;GO:2001259
biological_process	GO:1902609	(R)-2-hydroxy-alpha-linolenic acid biosynthetic process
	is_a	GO:0006636;GO:0042759	WAS	GO:0006636;GO:0042759;GO:1901617
biological_process	GO:1902616	O-acyl-L-carnitine transmembrane transport
	is_a	GO:0015697;GO:0055085	WAS	GO:0006844;GO:0055085
biological_process	GO:1902708	response to plumbagin
	is_a	GO:1901654	WAS	GO:0014070;GO:1901654
biological_process	GO:1902709	cellular response to plumbagin
	is_a	GO:1901655;GO:1902708	WAS	GO:0071407;GO:1901655;GO:1902708
biological_process	GO:1902800	positive regulation of phosphodiesterase I activity
	is_a	GO:0032075	WAS	GO:1902799;GO:1905779
biological_process	GO:1902933	isopentenol metabolic process
	is_a	GO:0120254	WAS	GO:0120254;GO:1901615
biological_process	GO:1902934	isopentenol biosynthetic process
	is_a	GO:0120255;GO:1902933	WAS	GO:0120255;GO:1901617;GO:1902933
biological_process	GO:1902943	positive regulation of voltage-gated chloride channel activity
	is_a	GO:1901529;GO:1903797	WAS	GO:1901529;GO:1902941;GO:1903797
biological_process	GO:1902960	negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
	is_a	GO:0010951;GO:1902992	WAS	GO:0010951;GO:1902959;GO:1902992;GO:1905246
biological_process	GO:1902961	positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
	is_a	GO:0010950;GO:1902993;GO:1905247	WAS	GO:0010950;GO:1902959;GO:1902993;GO:1905247
biological_process	GO:1903013	response to differentiation-inducing factor 1
	is_a	GO:0045472;GO:1901654	WAS	GO:0014070;GO:0045472;GO:1901654
biological_process	GO:1903014	cellular response to differentiation-inducing factor 1
	is_a	GO:0071362;GO:1901655;GO:1903013	WAS	GO:0071362;GO:0071407;GO:1901655;GO:1903013
biological_process	GO:1903016	negative regulation of exo-alpha-sialidase activity
	is_a	GO:0051346	WAS	GO:0051346;GO:1903015
biological_process	GO:1903017	positive regulation of exo-alpha-sialidase activity
	is_a	GO:0051345	WAS	GO:0051345;GO:1903015
biological_process	GO:1903033	positive regulation of microtubule plus-end binding
	is_a	GO:1904528	WAS	GO:1903031;GO:1904528
biological_process	GO:1903165	response to polycyclic arene
	is_a	GO:0042221	WAS	GO:0014070
biological_process	GO:1903166	cellular response to polycyclic arene
	is_a	GO:0070887;GO:1903165	WAS	GO:0071407;GO:1903165
biological_process	GO:1903281	positive regulation of calcium:sodium antiporter activity
	is_a	GO:1901021;GO:2000651	WAS	GO:1901021;GO:1903279;GO:2000651
biological_process	GO:1903282	regulation of glutathione peroxidase activity
	is_a	GO:0051341	WAS	GO:2000468
biological_process	GO:1903300	negative regulation of hexokinase activity
	is_a	GO:0033673;GO:0045912	WAS	GO:0033673;GO:0045912;GO:1903299
biological_process	GO:1903301	positive regulation of hexokinase activity
	is_a	GO:0033674	WAS	GO:0033674;GO:1903299
biological_process	GO:1903412	response to bile acid
	is_a	GO:0033993;GO:1901700	WAS	GO:0014070;GO:0033993;GO:1901700
biological_process	GO:1903413	cellular response to bile acid
	is_a	GO:0071396;GO:1901701;GO:1903412	WAS	GO:0071396;GO:0071407;GO:1901701;GO:1903412
biological_process	GO:1903442	response to lipoic acid
	is_a	GO:0070542	WAS	GO:0014070;GO:0070542
biological_process	GO:1903443	cellular response to lipoic acid
	is_a	GO:0071398;GO:1903442	WAS	GO:0071398;GO:0071407;GO:1903442
biological_process	GO:1903457	lactate catabolic process
	is_a	GO:0006089;GO:0072329	WAS	GO:0006089;GO:0072329;GO:1901616
biological_process	GO:1903491	response to simvastatin
	is_a	GO:0033993;GO:0036273	WAS	GO:0014070;GO:0033993;GO:0036273
biological_process	GO:1903492	response to acetylsalicylate
	is_a	GO:1901700	WAS	GO:0014070;GO:1901700
biological_process	GO:1903493	response to clopidogrel
	is_a	GO:1901698;GO:1901700	WAS	GO:0014070;GO:1901698;GO:1901700
biological_process	GO:1903494	response to dehydroepiandrosterone
	is_a	GO:0033993;GO:0097305;GO:1901654	WAS	GO:0014070;GO:0033993;GO:0097305;GO:1901654
biological_process	GO:1903495	cellular response to dehydroepiandrosterone
	is_a	GO:0071396;GO:0097306;GO:1901655;GO:1903494	WAS	GO:0071396;GO:0071407;GO:0097306;GO:1901655;GO:1903494
biological_process	GO:1903592	positive regulation of lysozyme activity
	is_a	GO:0051345	WAS	GO:0051345;GO:1903590
biological_process	GO:1903611	negative regulation of calcium-dependent ATPase activity
	is_a	GO:0032780	WAS	GO:0032780;GO:1903610
biological_process	GO:1903612	positive regulation of calcium-dependent ATPase activity
	is_a	GO:0032781	WAS	GO:0032781;GO:1903610
biological_process	GO:1903623	negative regulation of RNA polymerase III activity
	is_a	GO:0016480;GO:0051348	WAS	GO:0016480;GO:0051348;GO:1903622
biological_process	GO:1903755	positive regulation of SUMO transferase activity
	is_a	GO:0051347	WAS	GO:0051347;GO:1903182
biological_process	GO:1903914	negative regulation of fusion of virus membrane with host plasma membrane
	is_a	GO:0048525;GO:0051129;GO:1903913	WAS	GO:0046597;GO:0051129;GO:1903913
	relationship	negatively_regulates GO:0019064;negatively_regulates GO:0046718	WAS	negatively_regulates GO:0019064
biological_process	GO:1903925	response to bisphenol A
	is_a	GO:1901700	WAS	GO:0014070;GO:1901700
biological_process	GO:1903926	cellular response to bisphenol A
	is_a	GO:1901701;GO:1903925	WAS	GO:0071407;GO:1901701;GO:1903925
biological_process	GO:1903934	positive regulation of DNA primase activity
	is_a	GO:0051054;GO:0051347;GO:1902680	WAS	GO:0051054;GO:0051347;GO:1902680;GO:1903932
biological_process	GO:1903996	negative regulation of non-membrane spanning protein tyrosine kinase activity
	is_a	GO:0061099	WAS	GO:0061099;GO:1903995
biological_process	GO:1904014	response to serotonin
	is_a	GO:0071867;GO:1901700	WAS	GO:0014070;GO:0071867;GO:1901700
biological_process	GO:1904015	cellular response to serotonin
	is_a	GO:0071868;GO:1901701;GO:1904014	WAS	GO:0071407;GO:0071868;GO:1901701;GO:1904014
biological_process	GO:1904030	negative regulation of cyclin-dependent protein kinase activity
	is_a	GO:0006469	WAS	GO:0006469;GO:1904029
biological_process	GO:1904031	positive regulation of cyclin-dependent protein kinase activity
	is_a	GO:0045860	WAS	GO:0045860;GO:1904029
biological_process	GO:1904042	negative regulation of cystathionine beta-synthase activity
	is_a	GO:0051350	WAS	GO:0051350;GO:1904041
biological_process	GO:1904101	response to acadesine
	is_a	GO:1901698;GO:1901700	WAS	GO:0014070;GO:1901698;GO:1901700
biological_process	GO:1904102	cellular response to acadesine
	is_a	GO:1901699;GO:1901701;GO:1904101	WAS	GO:0071407;GO:1901699;GO:1901701;GO:1904101
biological_process	GO:1904187	regulation of transformation of host cell by virus
	is_a	GO:0043903	WAS	GO:0043903;GO:0050792
biological_process	GO:1904188	negative regulation of transformation of host cell by virus
	is_a	GO:0048519;GO:1904187	WAS	GO:0048525;GO:1904187
biological_process	GO:1904189	positive regulation of transformation of host cell by virus
	is_a	GO:0048518;GO:1904187	WAS	GO:0048524;GO:1904187
biological_process	GO:1904227	negative regulation of glycogen synthase activity, transferring glucose-1-phosphate
	is_a	GO:0051348	WAS	GO:0051348;GO:1904226
biological_process	GO:1904233	negative regulation of aconitate hydratase activity
	is_a	GO:0051350	WAS	GO:0051350;GO:1904232
biological_process	GO:1904234	positive regulation of aconitate hydratase activity
	is_a	GO:0051349	WAS	GO:0051349;GO:1904232
biological_process	GO:1904246	negative regulation of polynucleotide adenylyltransferase activity
	is_a	GO:0051348	WAS	GO:0051348;GO:1904245
biological_process	GO:1904247	positive regulation of polynucleotide adenylyltransferase activity
	is_a	GO:0051347	WAS	GO:0051347;GO:1904245
biological_process	GO:1904307	response to desipramine
	is_a	GO:1901698	WAS	GO:0014070;GO:1901698
biological_process	GO:1904308	cellular response to desipramine
	is_a	GO:1901699;GO:1904307	WAS	GO:0071407;GO:1901699;GO:1904307
biological_process	GO:1904310	cellular response to cordycepin
	is_a	GO:1901699;GO:1901701;GO:1904309	WAS	GO:0071407;GO:1901699;GO:1901701;GO:1904309
biological_process	GO:1904321	response to forskolin
	is_a	GO:0033993;GO:0097305;GO:1901654	WAS	GO:0014070;GO:0033993;GO:0097305;GO:1901654
biological_process	GO:1904322	cellular response to forskolin
	is_a	GO:0071396;GO:0097306;GO:1901655;GO:1904321	WAS	GO:0071396;GO:0071407;GO:0097306;GO:1901655;GO:1904321
biological_process	GO:1904373	response to kainic acid
	is_a	GO:0043200;GO:1901698;GO:1901700	WAS	GO:0014070;GO:0043200;GO:1901698;GO:1901700
biological_process	GO:1904374	cellular response to kainic acid
	is_a	GO:0071230;GO:1901699;GO:1901701;GO:1904373	WAS	GO:0071230;GO:0071407;GO:1901699;GO:1901701;GO:1904373
biological_process	GO:1904402	response to nocodazole
	is_a	GO:1901654;GO:1901698	WAS	GO:0014070;GO:1901654;GO:1901698
biological_process	GO:1904403	cellular response to nocodazole
	is_a	GO:1901655;GO:1901699;GO:1904402	WAS	GO:0071407;GO:1901655;GO:1901699;GO:1904402
biological_process	GO:1904425	negative regulation of GTP binding
	is_a	GO:0051100	WAS	GO:0051100;GO:1904424
biological_process	GO:1904426	positive regulation of GTP binding
	is_a	GO:0051099	WAS	GO:0051099;GO:1904424
biological_process	GO:1904434	positive regulation of ferrous iron binding
	is_a	GO:0051099	WAS	GO:0051099;GO:1904432
biological_process	GO:1904437	positive regulation of transferrin receptor binding
	is_a	GO:1900122	WAS	GO:1900122;GO:1904435
biological_process	GO:1904473	response to L-dopa
	is_a	GO:0043200;GO:1901700;GO:1904386	WAS	GO:0014070;GO:0043200;GO:1901700;GO:1904386
biological_process	GO:1904474	cellular response to L-dopa
	is_a	GO:0071230;GO:1901701;GO:1904387;GO:1904473	WAS	GO:0071230;GO:0071407;GO:1901701;GO:1904387;GO:1904473
biological_process	GO:1904481	response to tetrahydrofolate
	is_a	GO:1901698;GO:1901700	WAS	GO:0014070;GO:1901698;GO:1901700
biological_process	GO:1904482	cellular response to tetrahydrofolate
	is_a	GO:1901699;GO:1901701;GO:1904481	WAS	GO:0071407;GO:1901699;GO:1901701;GO:1904481
biological_process	GO:1904530	negative regulation of actin filament binding
	is_a	GO:0032091;GO:1904616	WAS	GO:1904529;GO:1904617
biological_process	GO:1904531	positive regulation of actin filament binding
	is_a	GO:0032092;GO:1904616	WAS	GO:1904529;GO:1904618
biological_process	GO:1904560	response to diphenidol
	is_a	GO:0097305;GO:1901698	WAS	GO:0014070;GO:0097305;GO:1901698
biological_process	GO:1904561	cellular response to diphenidol
	is_a	GO:0097306;GO:1901699;GO:1904560	WAS	GO:0071407;GO:0097306;GO:1901699;GO:1904560
biological_process	GO:1904567	response to wortmannin
	is_a	GO:1901654	WAS	GO:0014070;GO:1901654
biological_process	GO:1904568	cellular response to wortmannin
	is_a	GO:1901655;GO:1904567	WAS	GO:0071407;GO:1901655;GO:1904567
biological_process	GO:1904604	negative regulation of advanced glycation end-product receptor activity
	is_a	GO:2000272	WAS	GO:1904603;GO:2000272
biological_process	GO:1904610	response to 3,3',4,4',5-pentachlorobiphenyl
	is_a	GO:0042221	WAS	GO:0014070
biological_process	GO:1904611	cellular response to 3,3',4,4',5-pentachlorobiphenyl
	is_a	GO:0070887;GO:1904610	WAS	GO:0071407;GO:1904610
biological_process	GO:1904612	response to 2,3,7,8-tetrachlorodibenzodioxine
	is_a	GO:0042221	WAS	GO:0014070
biological_process	GO:1904613	cellular response to 2,3,7,8-tetrachlorodibenzodioxine
	is_a	GO:0070887;GO:1904612	WAS	GO:0071407;GO:1904612
biological_process	GO:1904614	response to biphenyl
	is_a	GO:0042221	WAS	GO:0014070
biological_process	GO:1904615	cellular response to biphenyl
	is_a	GO:0070887;GO:1904614	WAS	GO:0071407;GO:1904614
biological_process	GO:1904636	response to ionomycin
	is_a	GO:0045472;GO:0070542	WAS	GO:0014070;GO:0045472;GO:0070542
biological_process	GO:1904637	cellular response to ionomycin
	is_a	GO:0071362;GO:0071398;GO:1904636	WAS	GO:0071362;GO:0071398;GO:0071407;GO:1904636
biological_process	GO:1904639	cellular response to resveratrol
	is_a	GO:1901701;GO:1904638	WAS	GO:0071407;GO:1901701;GO:1904638
biological_process	GO:1904641	response to dinitrophenol
	is_a	GO:1901698;GO:1901700	WAS	GO:0014070;GO:1901698;GO:1901700
biological_process	GO:1904642	cellular response to dinitrophenol
	is_a	GO:1901699;GO:1901701;GO:1904641	WAS	GO:0071407;GO:1901699;GO:1901701;GO:1904641
biological_process	GO:1904643	response to curcumin
	is_a	GO:0045472;GO:1901654	WAS	GO:0014070;GO:0045472;GO:1901654
biological_process	GO:1904644	cellular response to curcumin
	is_a	GO:0071362;GO:1901655;GO:1904643	WAS	GO:0071362;GO:0071407;GO:1901655;GO:1904643
biological_process	GO:1904647	response to rotenone
	is_a	GO:1901654	WAS	GO:0014070;GO:1901654
biological_process	GO:1904648	cellular response to rotenone
	is_a	GO:1901655;GO:1904647	WAS	GO:0071407;GO:1901655;GO:1904647
biological_process	GO:1904726	regulation of replicative senescence
	is_a	GO:0010564	WAS	GO:0019222
biological_process	GO:1904727	negative regulation of replicative senescence
	is_a	GO:0010948;GO:1904726	WAS	GO:0009892;GO:1904726
biological_process	GO:1904728	positive regulation of replicative senescence
	is_a	GO:0090068;GO:1904726	WAS	GO:0009893;GO:1904726
biological_process	GO:1904743	negative regulation of telomeric DNA binding
	is_a	GO:0043392	WAS	GO:0043392;GO:1904742
biological_process	GO:1904744	positive regulation of telomeric DNA binding
	is_a	GO:0043388	WAS	GO:0043388;GO:1904742
biological_process	GO:1904797	negative regulation of core promoter binding
	is_a	GO:2000678	WAS	GO:1904796;GO:2000678
biological_process	GO:1904798	positive regulation of core promoter binding
	is_a	GO:2000679	WAS	GO:1904796;GO:2000679
biological_process	GO:1904916	L-lysine transmembrane transport from lysosomal lumen to cytosol
	is_a	GO:0089707;GO:0170063	WAS	GO:0007041;GO:0089707
biological_process	GO:1904917	L-arginine transmembrane transport from lysosomal lumen to cytosol
	is_a	GO:0170063;GO:1990818	WAS	GO:0007041;GO:1990818
biological_process	GO:1904918	L-histidine transmembrane transport from lysosomal lumen to cytosol
	is_a	GO:0032974;GO:0089709;GO:0170063	WAS	GO:0007041;GO:0032974;GO:0089709
biological_process	GO:1904919	L-cystine transmembrane transport from lysosomal lumen to cytosol
	is_a	GO:0015811;GO:0034489;GO:0170063;GO:1902475	WAS	GO:0007041;GO:0015811;GO:0034489;GO:1902475
biological_process	GO:1904959	regulation of cytochrome-c oxidase activity
	is_a	GO:0010155;GO:0032412;GO:0051341	WAS	GO:0010155;GO:0032412;GO:0051341;GO:1904732
biological_process	GO:1904960	positive regulation of cytochrome-c oxidase activity
	is_a	GO:0032414;GO:0051353;GO:1904959	WAS	GO:0032414;GO:0051353;GO:1904734;GO:1904959
biological_process	GO:1905012	regulation of 'de novo' NAD biosynthetic process from tryptophan
	is_a	GO:1900371;GO:1902688	WAS	GO:0090357;GO:1900371;GO:1902688
biological_process	GO:1905013	negative regulation of 'de novo' NAD biosynthetic process from tryptophan
	is_a	GO:1900372;GO:1902689;GO:1905012	WAS	GO:0033239;GO:0045763;GO:1900372;GO:1902689;GO:1905012
biological_process	GO:1905014	positive regulation of 'de novo' NAD biosynthetic process from tryptophan
	is_a	GO:1900373;GO:1902690;GO:1905012	WAS	GO:0090358;GO:1900373;GO:1902690;GO:1905012
biological_process	GO:1905097	regulation of guanyl-nucleotide exchange factor activity
	is_a	GO:0043087;GO:0051098	WAS	GO:0043087;GO:1904424
biological_process	GO:1905118	positive regulation of ribonucleoside-diphosphate reductase activity
	is_a	GO:0051353	WAS	GO:0051353;GO:1905117
biological_process	GO:1905119	response to haloperidol
	is_a	GO:0097305;GO:1901654;GO:1901698	WAS	GO:0014070;GO:0097305;GO:1901654;GO:1901698
biological_process	GO:1905120	cellular response to haloperidol
	is_a	GO:0097306;GO:1901655;GO:1901699;GO:1905119	WAS	GO:0071407;GO:0097306;GO:1901655;GO:1901699;GO:1905119
biological_process	GO:1905215	negative regulation of RNA binding
	is_a	GO:0051100	WAS	GO:0051100;GO:1905214
biological_process	GO:1905216	positive regulation of RNA binding
	is_a	GO:0051099	WAS	GO:0051099;GO:1905214
biological_process	GO:1905242	response to 3,3',5-triiodo-L-thyronine
	is_a	GO:0043200;GO:1901698;GO:1901700	WAS	GO:0014070;GO:0043200;GO:1901698;GO:1901700
biological_process	GO:1905243	cellular response to 3,3',5-triiodo-L-thyronine
	is_a	GO:0071230;GO:1901699;GO:1901701;GO:1905242	WAS	GO:0071230;GO:0071407;GO:1901699;GO:1901701;GO:1905242
biological_process	GO:1905247	positive regulation of aspartic-type peptidase activity
	is_a	GO:0010952	WAS	GO:0010952;GO:1905245
biological_process	GO:1905273	positive regulation of proton-transporting ATP synthase activity, rotational mechanism
	is_a	GO:0051351;GO:2001259	WAS	GO:0051351;GO:1905271;GO:2001259
biological_process	GO:1905307	response to miconazole
	is_a	GO:1901698	WAS	GO:0014070;GO:1901698
biological_process	GO:1905308	cellular response to miconazole
	is_a	GO:1901699;GO:1905307	WAS	GO:0071407;GO:1901699;GO:1905307
biological_process	GO:1905408	negative regulation of creatine transmembrane transporter activity
	is_a	GO:0022898;GO:0032410	WAS	GO:0032410;GO:1905407
biological_process	GO:1905546	cellular response to phenylpropanoid
	is_a	GO:0070887;GO:0080184	WAS	GO:0071407;GO:0080184
biological_process	GO:1905596	negative regulation of low-density lipoprotein particle receptor binding
	is_a	GO:1900121	WAS	GO:1900121;GO:1905595
biological_process	GO:1905597	positive regulation of low-density lipoprotein particle receptor binding
	is_a	GO:1900122	WAS	GO:1900122;GO:1905595
biological_process	GO:1905612	positive regulation of mRNA cap binding
	is_a	GO:1902416	WAS	GO:1902416;GO:1905610
biological_process	GO:1905778	negative regulation of exonuclease activity
	is_a	GO:0032074	WAS	GO:0032074;GO:1905777
biological_process	GO:1905795	cellular response to puromycin
	is_a	GO:1901699;GO:1901701;GO:1905794	WAS	GO:0071407;GO:1901699;GO:1901701;GO:1905794
biological_process	GO:1905834	response to pyrimidine ribonucleotide
	is_a	GO:0046683;GO:1901698;GO:1901700	WAS	GO:0014070;GO:0046683;GO:1901698;GO:1901700
biological_process	GO:1905835	cellular response to pyrimidine ribonucleotide
	is_a	GO:1901699;GO:1901701;GO:1905834	WAS	GO:0071407;GO:1901699;GO:1901701;GO:1905834
biological_process	GO:1905919	negative regulation of CoA-transferase activity
	is_a	GO:0051348	WAS	GO:0051348;GO:1905918
biological_process	GO:1905920	positive regulation of CoA-transferase activity
	is_a	GO:0051347	WAS	GO:0051347;GO:1905918
biological_process	GO:1905960	response to differentiation-inducing factor 2
	is_a	GO:0045472;GO:1901654	WAS	GO:0014070;GO:0045472;GO:1901654
biological_process	GO:1990054	response to temozolomide
	is_a	GO:1901698;GO:1901700	WAS	GO:0014070;GO:1901698;GO:1901700
biological_process	GO:1990216	symbiont-mediated activation of host transcription
	is_a	GO:0052026	WAS	GO:0044003
biological_process	GO:1990784	response to dsDNA
	is_a	GO:1901698	WAS	GO:0014070;GO:1901698
biological_process	GO:1990786	cellular response to dsDNA
	is_a	GO:1901699;GO:1990784	WAS	GO:0071407;GO:1901699;GO:1990784
biological_process	GO:1990968	modulation by host of RNA binding by virus
	is_a	GO:0044868	WAS	GO:0044092;GO:0044868;GO:1905214
biological_process	GO:2000276	negative regulation of oxidative phosphorylation uncoupler activity
	is_a	GO:0022898;GO:0032410;GO:1904063	WAS	GO:0032410;GO:1904063;GO:2000275
biological_process	GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity
	is_a	GO:0022898;GO:0032411	WAS	GO:0032411;GO:2000275
biological_process	GO:2000363	positive regulation of prostaglandin-E synthase activity
	is_a	GO:0043085	WAS	GO:0010912;GO:2000361
biological_process	GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity
	is_a	GO:0032781;GO:0043085	WAS	GO:0010912;GO:0032781;GO:2000371
biological_process	GO:2000470	positive regulation of peroxidase activity
	is_a	GO:0048522;GO:0051353	WAS	GO:0048522;GO:0051353;GO:2000468
biological_process	GO:2000657	negative regulation of apolipoprotein binding
	is_a	GO:0032091	WAS	GO:0032091;GO:2000656
biological_process	GO:2000772	regulation of cellular senescence
	is_a	GO:0050794	WAS	GO:0019222
biological_process	GO:2000773	negative regulation of cellular senescence
	is_a	GO:0048523;GO:2000772	WAS	GO:0009892;GO:2000772
biological_process	GO:2000774	positive regulation of cellular senescence
	is_a	GO:0048522;GO:2000772	WAS	GO:0009893;GO:2000772
biological_process	GO:2001145	negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
	is_a	GO:0010923	WAS	GO:0010923;GO:2001144
biological_process	GO:2001291	codeine metabolic process
	is_a	GO:0033076	WAS	GO:0033076;GO:1901376
biological_process	GO:2001292	codeine catabolic process
	is_a	GO:0071274;GO:2001291	WAS	GO:0071274;GO:1901377;GO:2001291
biological_process	GO:2001302	lipoxin A4 metabolic process
	is_a	GO:0001676;GO:0033559;GO:2001300	WAS	GO:0001676;GO:0033559;GO:1901615;GO:2001300
biological_process	GO:2001303	lipoxin A4 biosynthetic process
	is_a	GO:0006636;GO:0042759;GO:2001301;GO:2001302	WAS	GO:0006636;GO:0042759;GO:1901617;GO:2001301;GO:2001302
biological_process	GO:2001304	lipoxin B4 metabolic process
	is_a	GO:0001676;GO:0033559;GO:2001300	WAS	GO:0001676;GO:0033559;GO:1901615;GO:2001300
biological_process	GO:2001306	lipoxin B4 biosynthetic process
	is_a	GO:0006636;GO:0042759;GO:2001301;GO:2001304	WAS	GO:0006636;GO:0042759;GO:1901617;GO:2001301;GO:2001304
cellular_component	GO:0005953	CAAX-protein geranylgeranyltransferase complex
	is_a	GO:0140535;GO:1990234	WAS	GO:0032476;GO:0140535
cellular_component	GO:0005965	protein farnesyltransferase complex
	is_a	GO:1990234	WAS	GO:0032476
cellular_component	GO:0005968	Rab-protein geranylgeranyltransferase complex
	is_a	GO:1990234	WAS	GO:0032476
cellular_component	GO:0009519	middle lamella
	is_a	GO:0140047	WAS	GO:0031012
cellular_component	GO:0033165	interphotoreceptor matrix
	is_a	GO:0062023;GO:0140047	WAS	GO:0062023
cellular_component	GO:0035805	egg coat
	is_a	GO:0140047	WAS	GO:0031012
cellular_component	GO:0045025	mitochondrial degradosome
	is_a	GO:0098798;GO:1905354	WAS	GO:0000177;GO:0098798
cellular_component	GO:0060102	cuticular extracellular matrix
	is_a	GO:0062023;GO:0140047	WAS	GO:0062023
cellular_component	GO:0062039	biofilm matrix
	is_a	GO:0140047	WAS	GO:0031012
cellular_component	GO:0062129	chitin-based extracellular matrix
	is_a	GO:0140047	WAS	GO:0031012
cellular_component	GO:0070505	pollen coat
	is_a	GO:0140047	WAS	GO:0031012
cellular_component	GO:0070645	Ubisch body
	relationship	part_of GO:0140047	WAS	part_of GO:0031012
cellular_component	GO:0099535	synapse-associated extracellular matrix
	is_a	GO:0062023;GO:0140047	WAS	GO:0062023
cellular_component	GO:1990377	organomineral extracellular matrix
	is_a	GO:0140047	WAS	GO:0031012