# GORULE violations assigned by ARUK-UCL

## SUMMARY

This report generated on 2024-12-19

## Contents

[gorule-0000001](#gorule-0000001)[GAF lines are parsed according to GAF 2.2 specifications]{}

[gorule-0000008](#gorule-0000008)[No annotations should be made to uninformative high level terms]{}

[gorule-0000013](#gorule-0000013)[Taxon-appropriate annotation check]{}

[gorule-0000020](#gorule-0000020)[Automatic repair of annotations to merged or obsoleted terms]{}

[gorule-0000022](#gorule-0000022)[Check for, and filter, annotations made to retracted publications]{}

[gorule-0000046](#gorule-0000046)[The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.]{}

[gorule-0000061](#gorule-0000061)[Allowed gene product to term relations (gp2term)]{}

[gorule-0000065](#gorule-0000065)[Annotations to term that are candidates for obsoletion should be removed]{}

## MESSAGES

###gorule-0000001

GAF lines are parsed according to GAF 2.2 specifications

* total: 8
#### Messages
* WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral	URS0000812128_9606	URS0000812128_9606	acts_upstream_of	GO:0051897	PMID:31574452	IMP		P	Homo sapiens (human) H19 imprinted maternally expressed transcript		sRNA	taxon:9606	20200821	ARUK-UCL	occurs_in(CL:0000182)	`
* WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral	URS0000812128_9606	URS0000812128_9606	acts_upstream_of	GO:1900017	PMID:31574452	IMP		P	Homo sapiens (human) H19 imprinted maternally expressed transcript		sRNA	taxon:9606	20200821	ARUK-UCL	has_input(UniProtKB:P01579),occurs_in(CL:0000182)|has_input(UniProtKB:P05231),occurs_in(CL:0000182)|has_input(UniProtKB:Q14116),occurs_in(CL:0000182)	`
* WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral	URS0000812128_9606	URS0000812128_9606	acts_upstream_of	GO:1903428	PMID:31574452	IMP		P	Homo sapiens (human) H19 imprinted maternally expressed transcript		sRNA	taxon:9606	20200821	ARUK-UCL	occurs_in(CL:0000182)	`
* WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral	URS0000812128_9606	URS0000812128_9606	acts_upstream_of	GO:1903945	PMID:31574452	IMP		P	Homo sapiens (human) H19 imprinted maternally expressed transcript		sRNA	taxon:9606	20200821	ARUK-UCL		`
* WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral	URS0000812128_9606	URS0000812128_9606	acts_upstream_of	GO:2000378	PMID:31574452	IMP		P	Homo sapiens (human) H19 imprinted maternally expressed transcript		sRNA	taxon:9606	20230717	ARUK-UCL	occurs_in(CL:0000182)	`
* WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral	URS0000812128_9606	URS0000812128_9606	acts_upstream_of	GO:2001170	PMID:31574452	IMP		P	Homo sapiens (human) H19 imprinted maternally expressed transcript		sRNA	taxon:9606	20200821	ARUK-UCL	occurs_in(CL:0000182)	`
* WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral	URS0000812128_9606	URS0000812128_9606	involved_in	GO:0035196	PMID:31574452	IMP		P	Homo sapiens (human) H19 imprinted maternally expressed transcript		sRNA	taxon:9606	20200821	ARUK-UCL	has_input(RNAcentral:URS00004E5112_9606),occurs_in(CL:0000182)	`
* WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral	URS0000812128_9606	URS0000812128_9606	involved_in	GO:0098586	PMID:31574452	IMP		P	Homo sapiens (human) H19 imprinted maternally expressed transcript		sRNA	taxon:9606|taxon:10407	20200821	ARUK-UCL	occurs_in(CL:0000182)	`

###gorule-0000008

No annotations should be made to uninformative high level terms

* total: 33
#### Messages
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI	MGI:97321	Ngf	involved_in	GO:0043388	PMID:10362258	IMP		P	Beta-nerve growth factor		protein	taxon:10090	20180124	ARUK-UCL	has_input(UniProtKB:B2RWS6),has_input(UniProtKB:P38936),has_input(CHEBI:4705)|has_input(UniProtKB:O89090),has_input(UniProtKB:P38936),has_input(CHEBI:4705)|has_input(UniProtKB:O70494),has_input(UniProtKB:P38936),has_input(CHEBI:4705)	
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI	MGI:95629	Slc6a13	enables	GO:0005368	PMID:22896705	IMP		F	Sodium- and chloride-dependent GABA transporter 2		protein	taxon:10090	20200605	ARUK-UCL	part_of(UBERON:0002107)	
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI	MGI:1341865	Mark3	involved_in	GO:0032092	PMID:9543386	ISS	UniProtKB:P27448	P	MAP/microtubule affinity-regulating kinase 3		protein	taxon:10090	20180328	ARUK-UCL	has_input(UniProtKB:P48967),has_input(UniProtKB:P63101)	
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	O00501	CLDN5	involved_in	GO:0032092	PMID:25323998	IMP		P	Claudin-5	CLDN5|AWAL|TMVCF	protein	taxon:9606	20190702	ARUK-UCL	occurs_in(CL:0002585),has_input(UniProtKB:O95832),has_input(UniProtKB:P57739)|occurs_in(CL:0002586),has_input(UniProtKB:O95832),has_input(UniProtKB:P57739)	UniProtKB:O00501
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	O43504	LAMTOR5	acts_upstream_of	GO:1905636	PMID:21343296	IDA		P	Ragulator complex protein LAMTOR5	LAMTOR5|HBXIP|XIP	protein	taxon:9606	20191029	ARUK-UCL	has_input(UniProtKB:Q04206)	UniProtKB:O43504
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	O95816	BAG2	involved_in	GO:0032091	PMID:16207813	IDA		P	BAG family molecular chaperone regulator 2	BAG2	protein	taxon:9606	20180305	ARUK-UCL	has_input(UniProtKB:Q9UNE7),has_input(UniProtKB:P62837),negatively_regulates(GO:0061630)	UniProtKB:O95816
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P01138	NGF	involved_in	GO:0043388	PMID:10362258	ISS	UniProtKB:P01139	P	Beta-nerve growth factor	NGF|NGFB	protein	taxon:9606	20180124	ARUK-UCL	has_input(UniProtKB:Q09472),has_input(UniProtKB:P38936),has_input(CHEBI:4705)|has_input(UniProtKB:P08047),has_input(UniProtKB:P38936),has_input(CHEBI:4705)|has_input(UniProtKB:Q02447),has_input(UniProtKB:P38936),has_input(CHEBI:4705)	UniProtKB:P01138
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P11137	MAP2	involved_in	GO:1904527	GO_REF:0000024	ISS	UniProtKB:P15146	P	Microtubule-associated protein 2	MAP2	protein	taxon:9606	20210816	ARUK-UCL	has_input(UniProtKB:P33176)	UniProtKB:P11137
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P13866	SLC5A1	located_in	GO:0043229	GO_REF:0000024	ISS	UniProtKB:P53790	C	Sodium/glucose cotransporter 1	SLC5A1|NAGT|SGLT1	protein	taxon:9606	20200323	ARUK-UCL	part_of(CL:0000540),part_of(UBERON:0000955)|part_of(CL:2000044),part_of(UBERON:0000955)	UniProtKB:P13866
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P16615	ATP2A2	involved_in	GO:1900121	PMID:18068335	IMP		P	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	ATP2A2|ATP2B	protein	taxon:9606	20191001	ARUK-UCL	occurs_in(CL:0000233),part_of(GO:0006874)	UniProtKB:P16615
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P24001	IL32	acts_upstream_of	GO:1905636	PMID:23729669	IDA		P	Interleukin-32	IL32|NK4|TAIF	protein	taxon:9606	20211118	ARUK-UCL	has_input(UniProtKB:Q04206)	UniProtKB:P24001-1
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P27448	MARK3	involved_in	GO:0032092	PMID:9543386	IDA		P	MAP/microtubule affinity-regulating kinase 3	MARK3|CTAK1|EMK2	protein	taxon:9606	20180328	ARUK-UCL	has_input(UniProtKB:P30307),has_input(UniProtKB:P63104)	UniProtKB:P27448
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P31641	SLC6A6	enables	GO:0005368	GO_REF:0000024	ISS	UniProtKB:P31643	F	Sodium- and chloride-dependent taurine transporter	SLC6A6	protein	taxon:9606	20200602	ARUK-UCL	has_target_start_location(GO:0009897),has_target_end_location(GO:0009898)	UniProtKB:P31641
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P31641	SLC6A6	enables	GO:0005368	PMID:19074966	IDA		F	Sodium- and chloride-dependent taurine transporter	SLC6A6	protein	taxon:9606	20200603	ARUK-UCL	has_target_start_location(GO:0009897),has_target_end_location(GO:0009898)	UniProtKB:P31641
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P31641	SLC6A6	enables	GO:0005368	PMID:23519128	IMP		F	Sodium- and chloride-dependent taurine transporter	SLC6A6	protein	taxon:9606	20200602	ARUK-UCL	occurs_in(CL:0000523),has_target_start_location(GO:0009897),has_target_end_location(GO:0009898)	UniProtKB:P31641
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P31749	AKT1	involved_in	GO:0032091	PMID:18292230	IMP		P	RAC-alpha serine/threonine-protein kinase	AKT1|PKB|RAC	protein	taxon:9606	20180201	ARUK-UCL	has_input(UniProtKB:Q9UNE7),has_input(UniProtKB:P10636)	UniProtKB:P31749
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P51451	BLK	involved_in	GO:0032092	PMID:23555801	IMP		P	Tyrosine-protein kinase Blk	BLK	protein	taxon:9606	20210420	ARUK-UCL	has_input(UniProtKB:P16885),has_input(UniProtKB:Q8NDB2),part_of(GO:0050853)	UniProtKB:P51451
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P62714	PPP2CB	involved_in	GO:1904528	GO_REF:0000024	ISS	UniProtKB:P62716	P	Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	PPP2CB	protein	taxon:9606	20171208	ARUK-UCL	has_input(UniProtKB:P46821)	UniProtKB:P62714
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P67775	PPP2CA	involved_in	GO:1904528	GO_REF:0000024	ISS	UniProtKB:P63331	P	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	PPP2CA	protein	taxon:9606	20171208	ARUK-UCL	has_input(UniProtKB:P46821)|has_input(UniProtKB:P11137)	UniProtKB:P67775
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q07954	LRP1	involved_in	GO:0032092	PMID:23386614	IGI	UniProtKB:P04925	P	Prolow-density lipoprotein receptor-related protein 1	LRP1|A2MR|APR	protein	taxon:9606	20170626	ARUK-UCL	has_input(ComplexPortal:CPX-1134),has_input(UniProtKB:P04925)	UniProtKB:Q07954
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q13526	PIN1	involved_in	GO:0032092	PMID:24964035	IDA		P	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	PIN1	protein	taxon:9606	20180516	ARUK-UCL	has_input(UniProtKB:Q15796),has_input(UniProtKB:P10636)	UniProtKB:Q13526
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q5T7W0	ZNF618	involved_in	GO:0035563	PMID:27129234	IDA		P	Zinc finger protein 618	ZNF618|KIAA1952	protein	taxon:9606	20200828	ARUK-UCL		UniProtKB:Q5T7W0
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q6IQ55	TTBK2	involved_in	GO:1904527	PMID:26323690	IDA		P	Tau-tubulin kinase 2	TTBK2|KIAA0847	protein	taxon:9606	20171106	ARUK-UCL	has_input(UniProtKB:O00139)	UniProtKB:Q6IQ55
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q7KZI7	MARK2	involved_in	GO:1904526	PMID:24251416	ISS	UniProtKB:O08679	P	Serine/threonine-protein kinase MARK2	MARK2|EMK1	protein	taxon:9606	20180515	ARUK-UCL	has_input(UniProtKB:P10636)	UniProtKB:Q7KZI7
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q7Z2H8	SLC36A1	enables	GO:0005368	PMID:19074966	IDA		F	Proton-coupled amino acid transporter 1	SLC36A1|PAT1	protein	taxon:9606	20200603	ARUK-UCL	has_target_start_location(GO:0009897),has_target_end_location(GO:0009898)	UniProtKB:Q7Z2H8
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q93084	ATP2A3	involved_in	GO:1900121	PMID:18068335	IMP		P	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	ATP2A3	protein	taxon:9606	20191001	ARUK-UCL	occurs_in(CL:0000233),part_of(GO:0006874)	UniProtKB:Q93084
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q9NSD5	SLC6A13	enables	GO:0005368	GO_REF:0000024	ISS	UniProtKB:P31646	F	Sodium- and chloride-dependent GABA transporter 2	SLC6A13|GAT2	protein	taxon:9606	20200608	ARUK-UCL	part_of(CL:0000182),has_target_start_location(GO:0009897),has_target_end_location(GO:0009898)	UniProtKB:Q9NSD5
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q9NSD5	SLC6A13	enables	GO:0005368	GO_REF:0000024	ISS	UniProtKB:P31649	F	Sodium- and chloride-dependent GABA transporter 2	SLC6A13|GAT2	protein	taxon:9606	20200605	ARUK-UCL	part_of(UBERON:0002107)	UniProtKB:Q9NSD5
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`ComplexPortal	CPX-1120	abeta-40-42-oligomer_human	involved_in	GO:0032092	PMID:29518356	IDA		P	Amyloid-beta protein 40/42 oligomeric complex	fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 40/42 heterooligomer|beta-amyloid protein 40/42 complex|beta-amyloid-40/42 complex|beta amyloid protein 40/42 complex|amyloid-beta-40/42 complex|amyloid beta protein 40/42 complex|amyloid-beta protein 40/42 heterooligomer|amyloid-beta-40/42 heterooligomer|amyloid beta protein 40/42 heterooligomer|beta-amyloid-40/42 heterooligomer|beta amyloid protein 40/42 heterooligomer|Abeta protein 40/42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex|pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer	protein_complex	taxon:9606	20181212	ARUK-UCL	occurs_in(CL:0000129),has_input(UniProtKB:O43914),has_input(UniProtKB:Q9NZC2)	
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`ComplexPortal	CPX-1134	abeta-42-oligomer_human	involved_in	GO:0032092	PMID:24658113	IDA		P	Amyloid-beta protein 42 oligomeric complex	pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex	protein_complex	taxon:9606	20170627	ARUK-UCL	occurs_in(CL:0002608),has_input(UniProtKB:P54764),has_input(UniProtKB:P00519)	
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`ComplexPortal	CPX-1134	abeta-42-oligomer_human	involved_in	GO:0044092	PMID:23386614	IDA		P	Amyloid-beta protein 42 oligomeric complex	pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex	protein_complex	taxon:9606	20170626	ARUK-UCL	has_input(UniProtKB:P04156),positively_regulates(GO:0034205)	
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`RNAcentral	URS00003B95DA_9606	URS00003B95DA_9606	involved_in	GO:1900131	PMID:24608080	IDA		P	Homo sapiens (human) hsa-miR-27a-3p		miRNA	taxon:9606	20190116	ARUK-UCL	occurs_in(CL:0000517)	
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`RNAcentral	URS000059311D_9606	URS000059311D_9606	involved_in	GO:1900131	PMID:24608080	IDA		P	Homo sapiens (human) hsa-miR-27b-3p		miRNA	taxon:9606	20190116	ARUK-UCL	occurs_in(CL:0000517)	
`

###gorule-0000013

Taxon-appropriate annotation check

* total: 19
#### Messages
* ERROR - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	O75116	ROCK2	enables	GO:0050321	PMID:28386764	NAS		F	Rho-associated protein kinase 2	ROCK2|KIAA0619	protein	taxon:9606	20181030	ARUK-UCL		UniProtKB:O75116
`
* ERROR - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	P06241	FYN	enables	GO:0050321	PMID:28386764	NAS		F	Tyrosine-protein kinase Fyn	FYN	protein	taxon:9606	20181030	ARUK-UCL		UniProtKB:P06241
`
* ERROR - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	P27448	MARK3	enables	GO:0050321	PMID:28386764	NAS		F	MAP/microtubule affinity-regulating kinase 3	MARK3|CTAK1|EMK2	protein	taxon:9606	20181030	ARUK-UCL		UniProtKB:P27448
`
* ERROR - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	P49840	GSK3A	enables	GO:0050321	PMID:28386764	NAS		F	Glycogen synthase kinase-3 alpha	GSK3A	protein	taxon:9606	20181030	ARUK-UCL		UniProtKB:P49840
`
* ERROR - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	P49841	GSK3B	enables	GO:0050321	PMID:28386764	NAS		F	Glycogen synthase kinase-3 beta	GSK3B	protein	taxon:9606	20181030	ARUK-UCL		UniProtKB:P49841
`
* ERROR - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	Q00535	CDK5	enables	GO:0050321	PMID:28386764	NAS		F	Cyclin-dependent kinase 5	CDK5|CDKN5|PSSALRE	protein	taxon:9606	20181030	ARUK-UCL		UniProtKB:Q00535
`
* ERROR - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	Q13131	PRKAA1	enables	GO:0050321	PMID:28386764	NAS		F	5'-AMP-activated protein kinase catalytic subunit alpha-1	PRKAA1|AMPK1	protein	taxon:9606	20181030	ARUK-UCL		UniProtKB:Q13131
`
* ERROR - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	Q13464	ROCK1	enables	GO:0050321	PMID:28386764	NAS		F	Rho-associated protein kinase 1	ROCK1	protein	taxon:9606	20181030	ARUK-UCL		UniProtKB:Q13464
`
* ERROR - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	Q13627	DYRK1A	enables	GO:0050321	PMID:28386764	NAS		F	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	DYRK1A|DYRK|MNB|MNBH	protein	taxon:9606	20181030	ARUK-UCL		UniProtKB:Q13627
`
* ERROR - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	Q6IQ55	TTBK2	enables	GO:0050321	PMID:28386764	NAS		F	Tau-tubulin kinase 2	TTBK2|KIAA0847	protein	taxon:9606	20181030	ARUK-UCL		UniProtKB:Q6IQ55
`
* ERROR - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	Q7KZI7	MARK2	enables	GO:0050321	PMID:28386764	NAS		F	Serine/threonine-protein kinase MARK2	MARK2|EMK1	protein	taxon:9606	20181030	ARUK-UCL		UniProtKB:Q7KZI7
`
* ERROR - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	Q7L7X3	TAOK1	enables	GO:0050321	PMID:28386764	NAS		F	Serine/threonine-protein kinase TAO1	TAOK1|KIAA1361|MAP3K16|MARKK	protein	taxon:9606	20181030	ARUK-UCL		UniProtKB:Q7L7X3
`
* ERROR - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	Q8IWQ3	BRSK2	enables	GO:0050321	PMID:28386764	NAS		F	Serine/threonine-protein kinase BRSK2	BRSK2|C11orf7|PEN11B|SADA|STK29|HUSSY-12	protein	taxon:9606	20181030	ARUK-UCL		UniProtKB:Q8IWQ3
`
* ERROR - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	Q8TDC3	BRSK1	enables	GO:0050321	PMID:28386764	NAS		F	Serine/threonine-protein kinase BRSK1	BRSK1|KIAA1811|SAD1|SADB	protein	taxon:9606	20181030	ARUK-UCL		UniProtKB:Q8TDC3
`
* ERROR - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	Q96L34	MARK4	enables	GO:0050321	PMID:28386764	NAS		F	MAP/microtubule affinity-regulating kinase 4	MARK4|KIAA1860|MARKL1	protein	taxon:9606	20181030	ARUK-UCL		UniProtKB:Q96L34
`
* ERROR - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	Q9P0L2	MARK1	enables	GO:0050321	PMID:28386764	NAS		F	Serine/threonine-protein kinase MARK1	MARK1|KIAA1477|MARK	protein	taxon:9606	20181030	ARUK-UCL		UniProtKB:Q9P0L2
`
* ERROR - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	Q9UL54	TAOK2	enables	GO:0050321	PMID:28386764	NAS		F	Serine/threonine-protein kinase TAO2	TAOK2|KIAA0881|MAP3K17|PSK|PSK1|UNQ2971/PRO7431	protein	taxon:9606	20181030	ARUK-UCL		UniProtKB:Q9UL54
`
* WARNING - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	Q5TCY1	TTBK1	enables	GO:0050321	PMID:16923168	IDA		F	Tau-tubulin kinase 1	TTBK1|BDTK|KIAA1855	protein	taxon:9606	20190619	ARUK-UCL		UniProtKB:Q5TCY1
`
* WARNING - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	Q96L34	MARK4	enables	GO:0050321	PMID:27708431	IMP		F	MAP/microtubule affinity-regulating kinase 4	MARK4|KIAA1860|MARKL1	protein	taxon:9606	20180515	ARUK-UCL		UniProtKB:Q96L34
`

###gorule-0000020

Automatic repair of annotations to merged or obsoleted terms

* total: 25
#### Messages
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI	MGI:107656	Ifng	involved_in	GO:0007259	PMID:26227742	IGI	UniProtKB:Q62120	P	Interferon gamma		protein	taxon:10090	20201016	ARUK-UCL	occurs_in(CL:0000129),part_of(GO:0032760)|occurs_in(CL:0000129),part_of(GO:0045348)|occurs_in(CL:0000129),part_of(GO:0032731)|occurs_in(CL:0000129),part_of(GO:0051770)	
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI	MGI:96629	Jak2	involved_in	GO:0007259	PMID:26227742	IGI	UniProtKB:P01580	P	Tyrosine-protein kinase JAK2		protein	taxon:10090	20201016	ARUK-UCL	occurs_in(CL:0000129),part_of(GO:0032760)|occurs_in(CL:0000129),part_of(GO:0045348)|occurs_in(CL:0000129),part_of(GO:0032731)|occurs_in(CL:0000129),part_of(GO:0051770)	
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	O60674	JAK2	involved_in	GO:0007259	GO_REF:0000024	ISS	UniProtKB:Q62120	P	Tyrosine-protein kinase JAK2	JAK2	protein	taxon:9606	20201016	ARUK-UCL	occurs_in(CL:0000129),part_of(GO:0032760)|occurs_in(CL:0000129),part_of(GO:0045348)|occurs_in(CL:0000129),part_of(GO:0032731)|occurs_in(CL:0000129),part_of(GO:0051770)	UniProtKB:O60674
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	P01579	IFNG	involved_in	GO:0007259	GO_REF:0000024	ISS	UniProtKB:P01580	P	Interferon gamma	IFNG	protein	taxon:9606	20201016	ARUK-UCL	occurs_in(CL:0000129),part_of(GO:0032760)|occurs_in(CL:0000129),part_of(GO:0045348)|occurs_in(CL:0000129),part_of(GO:0032731)|occurs_in(CL:0000129),part_of(GO:0051770)	UniProtKB:P01579
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`RNAcentral	URS000075D95B_9606	URS000075D95B_9606	enables	GO:0140463	PMID:32482714	TAS		F	Homo sapiens (human) X inactive specific transcript (XIST)		lncRNA	taxon:9606	20230815	ARUK-UCL	part_of(GO:0060820)	
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`RNAcentral	URS0000DB8B87_9606	URS0000DB8B87_9606	enables	GO:0140463	PMID:31048766	TAS		F	Homo sapiens (human) X inactive specific transcript		lncRNA	taxon:9606	20230530	ARUK-UCL	part_of(GO:0060820)|part_of(GO:0051303)	
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	Q99538	LGMN	involved_in	GO:0097202	PMID:9821970	IDA		P	Legumain	LGMN|PRSC1	protein	taxon:9606	20180307	ARUK-UCL	has_input(UniProtKB:Q99538)	UniProtKB:Q99538
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	Q99538	LGMN	involved_in	GO:0097264	PMID:18374643	IDA		P	Legumain	LGMN|PRSC1	protein	taxon:9606	20180307	ARUK-UCL	part_of(GO:0097202)	UniProtKB:Q99538
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	Q99538	LGMN	involved_in	GO:0097264	PMID:9821970	IDA		P	Legumain	LGMN|PRSC1	protein	taxon:9606	20180307	ARUK-UCL	part_of(GO:0097202)	UniProtKB:Q99538
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	Q9NPP4	NLRC4	involved_in	GO:0097202	PMID:15882992	IGI	UniProtKB:P10749,UniProtKB:P29466	P	NLR family CARD domain-containing protein 4	NLRC4|CARD12|CLAN|CLAN1|IPAF|UNQ6189/PRO20215	protein	taxon:9606	20200319	ARUK-UCL	part_of(GO:0032731),has_input(UniProtKB:P29466),part_of(GO:0010954)	UniProtKB:Q9NPP4
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`ComplexPortal	CPX-1134	abeta-42-oligomer_human	involved_in	GO:0097202	PMID:23386614	TAS		P	Amyloid-beta protein 42 oligomeric complex	pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex	protein_complex	taxon:9606	20170626	ARUK-UCL		
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`RNAcentral	URS0000316FA5_9606	URS0000316FA5_9606	involved_in	GO:1902949	PMID:24027266	ISS	RNAcentral:URS0000316FA5_10116	P	Homo sapiens (human) hsa-miR-26b-5p		miRNA	taxon:9606	20190307	ARUK-UCL	occurs_in(CL:0010012),has_input(UniProtKB:Q00535),has_input(UniProtKB:P10636)	
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	P01138	NGF	involved_in	GO:2001056	PMID:11927634	IGI	UniProtKB:P08138	P	Beta-nerve growth factor	NGF|NGFB	protein	taxon:9606	20170906	ARUK-UCL	positively_regulates(GO:0051402)	UniProtKB:P01138-PRO_0000019600
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB	P14921	ETS1	enables	GO:0030374	PMID:31146003	IMP		F	Protein C-ets-1	ETS1|EWSR2	protein	taxon:9606	20201215	ARUK-UCL	has_input(UniProtKB:P22736)	UniProtKB:P14921
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB	P19419	ELK1	enables	GO:0030374	PMID:31146003	IMP		F	ETS domain-containing protein Elk-1	ELK1	protein	taxon:9606	20201215	ARUK-UCL	has_input(UniProtKB:P22736)	UniProtKB:P19419
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB	P82094	TMF1	enables	GO:0030374	PMID:10428808	IDA		F	TATA element modulatory factor	TMF1|ARA160	protein	taxon:9606	20200605	ARUK-UCL	has_input(UniProtKB:P10275),part_of(GO:0030521)	UniProtKB:P82094
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB	Q96PN7	TRERF1	enables	GO:0030374	PMID:17015480	IDA		F	Transcriptional-regulating factor 1	TRERF1|BCAR2|RAPA|TREP132	protein	taxon:9606	20200604	ARUK-UCL	has_input(UniProtKB:P06401)	UniProtKB:Q96PN7
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB	Q96PN7	TRERF1	enables	GO:0033142	PMID:17015480	IPI	UniProtKB:P06401	F	Transcriptional-regulating factor 1	TRERF1|BCAR2|RAPA|TREP132	protein	taxon:9606	20200604	ARUK-UCL	part_of(GO:0030374),part_of(GO:0045944)	UniProtKB:Q96PN7
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB	Q9H0E9	BRD8	enables	GO:0030374	PMID:9368056	IDA		F	Bromodomain-containing protein 8	BRD8|SMAP|SMAP2	protein	taxon:9606	20200610	ARUK-UCL		UniProtKB:Q9H0E9
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`RNAcentral	URS000049A7EB_9606	URS000049A7EB_9606	acts_upstream_of	GO:0031327	PMID:29048659	IDA		P	Homo sapiens (human) hsa-miR-520c-3p		miRNA	taxon:9606	20200130	ARUK-UCL	has_input(UniProtKB:P08670)	
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`RNAcentral	URS00004AE8D3_9606	URS00004AE8D3_9606	acts_upstream_of_or_within	GO:0031327	PMID:30210926	IDA		P	Homo sapiens (human) hsa-miR-506-3p		miRNA	taxon:9606	20200312	ARUK-UCL	has_input(UniProtKB:P46013)	
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`RNAcentral	URS00004AE8D3_9606	URS00004AE8D3_9606	involved_in	GO:0031327	PMID:30210926	IDA		P	Homo sapiens (human) hsa-miR-506-3p		miRNA	taxon:9606	20200312	ARUK-UCL	has_input(UniProtKB:P08670)	
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB	P10145	CXCL8	acts_upstream_of_or_within	GO:0031328	PMID:29048659	IDA		P	Interleukin-8	CXCL8|IL8	protein	taxon:9606	20200526	ARUK-UCL	has_input(UniProtKB:P02751)	UniProtKB:P10145
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB	P10145	CXCL8	acts_upstream_of_or_within	GO:0031328	PMID:29048659	IDA		P	Interleukin-8	CXCL8|IL8	protein	taxon:9606	20200526	ARUK-UCL	has_input(UniProtKB:P08670)	UniProtKB:P10145
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB	P05549	TFAP2A	enables	GO:0140536	PMID:31146003	IMP		F	Transcription factor AP-2-alpha	TFAP2A|AP2TF|TFAP2	protein	taxon:9606	20201215	ARUK-UCL	has_input(UniProtKB:P22736)	UniProtKB:P05549
`

###gorule-0000022

Check for, and filter, annotations made to retracted publications

* total: 25
#### Messages
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`UniProtKB	P05067	APP	involved_in	GO:0007613	PMID:16541076	IGI	ComplexPortal:CPX-1134	P	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20170626	ARUK-UCL		UniProtKB:P05067-PRO_0000000092
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`UniProtKB	P05067	APP	located_in	GO:0005615	PMID:16541076	IDA		C	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20170626	ARUK-UCL		UniProtKB:P05067-PRO_0000000092
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`UniProtKB	P05067	APP	located_in	GO:0016020	PMID:16541076	IDA		C	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20170208	ARUK-UCL		UniProtKB:P05067-PRO_0000000094
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`UniProtKB	P05067	APP	located_in	GO:0016020	PMID:16541076	IDA		C	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20170208	ARUK-UCL		UniProtKB:P05067-PRO_0000384574
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`UniProtKB	P05231	IL6	involved_in	GO:0045669	PMID:30545407	IDA		P	Interleukin-6	IL6|IFNB2	protein	taxon:9606	20230418	ARUK-UCL		UniProtKB:P05231
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`ComplexPortal	CPX-1134	abeta-42-oligomer_human	involved_in	GO:0007613	PMID:16541076	IGI	UniProtKB:P05067-PRO_0000000092	P	Amyloid-beta protein 42 oligomeric complex	pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex	protein_complex	taxon:9606	20170626	ARUK-UCL		
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`ComplexPortal	CPX-1134	abeta-42-oligomer_human	located_in	GO:0005615	PMID:16541076	IDA		C	Amyloid-beta protein 42 oligomeric complex	pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex	protein_complex	taxon:9606	20170626	ARUK-UCL		
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`ComplexPortal	CPX-1134	abeta-42-oligomer_human	located_in	GO:0005737	PMID:16541076	IDA		C	Amyloid-beta protein 42 oligomeric complex	pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex	protein_complex	taxon:9606	20181214	ARUK-UCL		
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`RNAcentral	URS00002C0FCB_9606	URS00002C0FCB_9606	enables	GO:0003730	PMID:27364335	IDA		F	Homo sapiens (human) hsa-miR-130b-3p		miRNA	taxon:9606	20200821	ARUK-UCL	has_input(UniProtKB:P37231),part_of(GO:0035195)	
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`RNAcentral	URS00002C0FCB_9606	URS00002C0FCB_9606	enables	GO:1903231	PMID:27364335	IDA		F	Homo sapiens (human) hsa-miR-130b-3p		miRNA	taxon:9606	20200821	ARUK-UCL	has_input(UniProtKB:P37231)	
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`RNAcentral	URS00002C0FCB_9606	URS00002C0FCB_9606	involved_in	GO:0035195	PMID:27364335	IDA		P	Homo sapiens (human) hsa-miR-130b-3p		miRNA	taxon:9606	20200821	ARUK-UCL	has_input(UniProtKB:P37231)	
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`RNAcentral	URS0000355E82_9606	URS0000355E82_9606	acts_upstream_of	GO:0045668	PMID:30545407	IMP		P	Homo sapiens (human) hsa-miR-665		miRNA	taxon:9606	20230418	ARUK-UCL		
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`RNAcentral	URS0000355E82_9606	URS0000355E82_9606	enables	GO:0106222	PMID:30545407	IDA		F	Homo sapiens (human) hsa-miR-665		miRNA	taxon:9606	20230418	ARUK-UCL	has_input(RNAcentral:URS0000EF3C68_9606),occurs_in(CL:0002570)	
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`RNAcentral	URS0000355E82_9606	URS0000355E82_9606	enables	GO:1903231	PMID:30545407	IDA		F	Homo sapiens (human) hsa-miR-665		miRNA	taxon:9606	20230418	ARUK-UCL	has_input(UniProtKB:P05231),occurs_in(CL:0002570)	
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`RNAcentral	URS0000355E82_9606	URS0000355E82_9606	involved_in	GO:0031047	PMID:30545407	IDA		P	Homo sapiens (human) hsa-miR-665		miRNA	taxon:9606	20230418	ARUK-UCL	has_input(RNAcentral:URS0000EF3C68_9606),occurs_in(CL:0002570)	
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`RNAcentral	URS0000355E82_9606	URS0000355E82_9606	involved_in	GO:0035195	PMID:30545407	IDA		P	Homo sapiens (human) hsa-miR-665		miRNA	taxon:9606	20230418	ARUK-UCL	has_input(UniProtKB:P05231),occurs_in(CL:0002570),causally_upstream_of(GO:0045668)	
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`RNAcentral	URS00004BCD9C_9606	URS00004BCD9C_9606	enables	GO:1903231	PMID:24418124	IDA		F	Homo sapiens (human) hsa-miR-16-5p		miRNA	taxon:9606	20230717	ARUK-UCL	has_input(UniProtKB:P10415),occurs_in(UBERON:0000955),part_of(GO:0035195)	
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`RNAcentral	URS00004BCD9C_9606	URS00004BCD9C_9606	enables	GO:1903231	PMID:24418124	IDA		F	Homo sapiens (human) hsa-miR-16-5p		miRNA	taxon:9606	20230717	ARUK-UCL	has_input(UniProtKB:P19838),occurs_in(UBERON:0000955),part_of(GO:0035279)	
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`RNAcentral	URS00004BCD9C_9606	URS00004BCD9C_9606	involved_in	GO:0035195	PMID:24418124	IDA		P	Homo sapiens (human) hsa-miR-16-5p		miRNA	taxon:9606	20230717	ARUK-UCL	has_input(UniProtKB:P10415),occurs_in(UBERON:0000955)	
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`RNAcentral	URS00004BCD9C_9606	URS00004BCD9C_9606	involved_in	GO:0035279	PMID:24418124	IDA		P	Homo sapiens (human) hsa-miR-16-5p		miRNA	taxon:9606	20230717	ARUK-UCL	has_input(UniProtKB:P19838),occurs_in(UBERON:0000955)	
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`RNAcentral	URS000075BB37_9606	URS000075BB37_9606	acts_upstream_of	GO:0045669	PMID:30545407	IDA		P	Homo sapiens (human) HIF1A antisense RNA 2 (HIF1A-AS2)		lncRNA	taxon:9606	20230418	ARUK-UCL		
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`RNAcentral	URS000075BB37_9606	URS000075BB37_9606	enables	GO:0035198	PMID:30545407	IDA		F	Homo sapiens (human) HIF1A antisense RNA 2 (HIF1A-AS2)		lncRNA	taxon:9606	20230418	ARUK-UCL	has_input(RNAcentral:URS0000355E82_9606)	
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`RNAcentral	URS000075BB37_9606	URS000075BB37_9606	enables	GO:0140869	PMID:30545407	IDA		F	Homo sapiens (human) HIF1A antisense RNA 2 (HIF1A-AS2)		lncRNA	taxon:9606	20230418	ARUK-UCL	has_input(RNAcentral:URS0000355E82_9606)	
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`RNAcentral	URS000075BB37_9606	URS000075BB37_9606	involved_in	GO:0000512	PMID:30545407	IDA		P	Homo sapiens (human) HIF1A antisense RNA 2 (HIF1A-AS2)		lncRNA	taxon:9606	20230418	ARUK-UCL	has_input(RNAcentral:URS0000355E82_9606)	
`
* ERROR - Violates GO Rule:GORULE:0000022: Check for, and filter, annotations made to retracted publications--`RNAcentral	URS000075BB37_9606	URS000075BB37_9606	involved_in	GO:2000627	PMID:30545407	IDA		P	Homo sapiens (human) HIF1A antisense RNA 2 (HIF1A-AS2)		lncRNA	taxon:9606	20230522	ARUK-UCL	has_input(RNAcentral:URS0000355E82_9606)	
`

###gorule-0000046

The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

* total: 14
#### Messages
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:1196458	Scarb2	enables	GO:0042803	PMID:29199275	IPI	UniProtKB:O35114	F	Lysosome membrane protein 2		protein	taxon:10090	20181031	ARUK-UCL		
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:97275	Myod1	enables	GO:0042803	PMID:10652346	IPI	UniProtKB:P10085	F	Myoblast determination protein 1		protein	taxon:10090	20230314	ARUK-UCL		
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:894311	Lilrb3	enables	GO:0042803	PMID:24052308	IPI	UniProtKB:P97484	F	Leukocyte immunoglobulin-like receptor subfamily B member 3		protein	taxon:10090	20230314	ARUK-UCL	causally_upstream_of(GO:0001540)	
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P05067	APP	enables	GO:0042803	PMID:15447668	IPI	UniProtKB:P05067-PRO_0000000092	F	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20230314	ARUK-UCL		UniProtKB:P05067-PRO_0000000092
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P05067	APP	enables	GO:0042803	PMID:15447668	IPI	UniProtKB:P05067-PRO_0000000093	F	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20230314	ARUK-UCL		UniProtKB:P05067-PRO_0000000093
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P05067	APP	enables	GO:0042803	PMID:18568035	IPI	UniProtKB:P05067-PRO_0000000092	F	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20170213	ARUK-UCL		UniProtKB:P05067-PRO_0000000092
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P05067	APP	enables	GO:0042803	PMID:22179788	IPI	UniProtKB:P05067-PRO_0000000093	F	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20230314	ARUK-UCL		UniProtKB:P05067-PRO_0000000093
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P05067	APP	enables	GO:0042803	PMID:23386614	IPI	UniProtKB:P05067-PRO_0000000092	F	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20230314	ARUK-UCL		UniProtKB:P05067-PRO_0000000092
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P05067	APP	involved_in	GO:0051260	PMID:15447668	IPI	UniProtKB:P05067-PRO_0000000092	P	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20230314	ARUK-UCL		UniProtKB:P05067-PRO_0000000092
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P05067	APP	involved_in	GO:0051260	PMID:15447668	IPI	UniProtKB:P05067-PRO_0000000093	P	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20230314	ARUK-UCL	has_input(UniProtKB:P05067-PRO_0000000093)	UniProtKB:P05067-PRO_0000000093
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P05067	APP	involved_in	GO:0051260	PMID:18602473	IPI	UniProtKB:P05067-PRO_0000000093	P	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20230314	ARUK-UCL		UniProtKB:P05067-PRO_0000000093
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P05067	APP	involved_in	GO:0051260	PMID:23386614	IPI	UniProtKB:P05067-PRO_0000000092	P	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20230314	ARUK-UCL	has_input(UniProtKB:P05067)	UniProtKB:P05067-PRO_0000000092
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P10636	MAPT	involved_in	GO:0051260	PMID:26704708	IPI	UniProtKB:P10636-8	P	Microtubule-associated protein tau	MAPT|MAPTL|MTBT1|TAU	protein	taxon:9606	20230314	ARUK-UCL	happens_during(UBERON:0000112),happens_during(GO:0018105),occurs_in(UBERON:0002421),regulates(GO:0007611)|happens_during(UBERON:0018241),happens_during(GO:0018105),occurs_in(UBERON:0002421),regulates(GO:0007611)	UniProtKB:P10636-8
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P15172	MYOD1	enables	GO:0042803	GO_REF:0000024	ISS	UniProtKB:P10085	F	Myoblast determination protein 1	MYOD1|BHLHC1|MYF3|MYOD	protein	taxon:9606	20230314	ARUK-UCL		UniProtKB:P15172
`

###gorule-0000061

Allowed gene product to term relations (gp2term)

* total: 9
#### Messages
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`MGI	MGI:96247	Hsp90ab1	is_active_in	GO:0101031	PMID:17517623	IMP		C	Heat shock protein HSP 90-beta		protein	taxon:10090	20240320	ARUK-UCL		
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`MGI	MGI:2442926	Mettl14	is_active_in	GO:0036396	PMID:29290617	IDA		C	N(6)-adenosine-methyltransferase non-catalytic subunit METTL14		protein	taxon:10090	20240206	ARUK-UCL		
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB	O14745	NHERF1	is_active_in	GO:0098797	GO_REF:0000024	ISS	UniProtKB:Q9JJ19	C	Na(+)/H(+) exchange regulatory cofactor NHE-RF1	NHERF1|NHERF|SLC9A3R1	protein	taxon:9606	20200115	ARUK-UCL	part_of(UBERON:0000955)	UniProtKB:O14745
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB	P02649	APOE	is_active_in	GO:0034360	PMID:7683668	IDA		C	Apolipoprotein E	APOE	protein	taxon:9606	20230531	ARUK-UCL		UniProtKB:P02649
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB	P02649	APOE	is_active_in	GO:0034361	PMID:7683668	IDA		C	Apolipoprotein E	APOE	protein	taxon:9606	20230531	ARUK-UCL		UniProtKB:P02649
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB	P08238	HSP90AB1	is_active_in	GO:0101031	PMID:17517623	IMP		C	Heat shock protein HSP 90-beta	HSP90AB1|HSP90B|HSPC2|HSPC3|HSPCB	protein	taxon:9606	20240320	ARUK-UCL		UniProtKB:P08238
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB	P31641	SLC6A6	is_active_in	GO:0098797	GO_REF:0000024	ISS	UniProtKB:P31643	C	Sodium- and chloride-dependent taurine transporter	SLC6A6	protein	taxon:9606	20200115	ARUK-UCL	part_of(UBERON:0000955)	UniProtKB:P31641
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB	Q9HCE5	METTL14	is_active_in	GO:0036396	PMID:29290617	IDA		C	N(6)-adenosine-methyltransferase non-catalytic subunit METTL14	METTL14|KIAA1627	protein	taxon:9606	20240206	ARUK-UCL		UniProtKB:Q9HCE5
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB	Q9Y2G2	CARD8	is_active_in	GO:0140634	PMID:15030775	IDA		C	Caspase recruitment domain-containing protein 8	CARD8|DACAR|KIAA0955|NDPP1	protein	taxon:9606	20240215	ARUK-UCL		UniProtKB:Q9Y2G2
`

###gorule-0000065

Annotations to term that are candidates for obsoletion should be removed

* total: 397
#### Messages
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:108092	Bin1	involved_in	GO:1902960	PMID:27179792	IMP		P	Myc box-dependent-interacting protein 1		protein	taxon:10090	20190717	ARUK-UCL	occurs_in(CL:0010012),has_output(UniProtKB:P12023-PRO_0000000119),has_input(UniProtKB:P56818)|occurs_in(CL:0010012),has_output(UniProtKB:P12023-PRO_0000000118),has_input(UniProtKB:P56818)|occurs_in(CL:0010012),has_output(UniProtKB:P12023-PRO_0000000116),has_input(UniProtKB:P56818)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1298217	Cst7	involved_in	GO:0010466	PMID:18256700	IDA		P	Cystatin-F		protein	taxon:10090	20190228	ARUK-UCL	has_input(UniProtKB:P97821)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:97769	Prnp	involved_in	GO:0032147	PMID:23386614	IGI	ComplexPortal:CPX-1134	P	Major prion protein		protein	taxon:10090	20210428	ARUK-UCL	has_input(UniProtKB:P06241),occurs_in(GO:0045121)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:97769	Prnp	involved_in	GO:0050730	PMID:22820466	IGI	UniProtKB:P39688	P	Major prion protein		protein	taxon:10090	20230517	ARUK-UCL	occurs_in(CL:0010012),part_of(GO:1904645),has_input(UniProtKB:Q01097)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:97769	Prnp	involved_in	GO:0050731	PMID:22820466	IMP		P	Major prion protein		protein	taxon:10090	20230517	ARUK-UCL	occurs_in(CL:0010012),part_of(GO:1904645),has_input(UniProtKB:P39688)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:96607	Itgam	involved_in	GO:2000363	PMID:18981141	IMP		P	Integrin alpha-M		protein	taxon:10090	20210429	ARUK-UCL	occurs_in(UBERON:0001891),occurs_in(CL:0000125),has_output(CHEBI:15551),part_of(GO:0033554)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:97810	Ptprc	involved_in	GO:0050731	PMID:18249142	IGI	UniProtKB:Q64455	P	Receptor-type tyrosine-protein phosphatase C		protein	taxon:10090	20180725	ARUK-UCL	has_input(UniProtKB:P25911)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:95499	Fcgr2	involved_in	GO:0051091	PMID:23921129	IMP		P	Low affinity immunoglobulin gamma Fc region receptor II		protein	taxon:10090	20230517	ARUK-UCL	occurs_in(CL:0010012),part_of(GO:1904646)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:96610	Itgb1	acts_upstream_of_or_within	GO:1901979	PMID:25716834	IMP		P	Integrin beta-1		protein	taxon:10090	20200116	ARUK-UCL	occurs_in(UBERON:0003528),occurs_in(CL:0000127)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:103250	Calm2	involved_in	GO:1901020	PMID:33199372	IDA		P	Calmodulin-2		protein	taxon:10090	20210421	ARUK-UCL	has_input(UniProtKB:Q8CGQ8),part_of(GO:1905913),occurs_in(UBERON:0000955)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:98282	Spi1	involved_in	GO:0051090	PMID:29924977	IMP		P	Transcription factor PU.1		protein	taxon:10090	20201202	ARUK-UCL	happens_during(GO:0002572),has_input(UniProtKB:Q60611)|happens_during(GO:0002572),has_input(UniProtKB:Q03347)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:95760	Slc6a9	acts_upstream_of	GO:1904782	PMID:15159536	IMP		P	Sodium- and chloride-dependent glycine transporter 1		protein	taxon:10090	20200612	ARUK-UCL	occurs_in(CL:1001571)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:104853	Hes1	involved_in	GO:0043433	PMID:10851137	IDA		P	Transcription factor HES-1		protein	taxon:10090	20200505	ARUK-UCL		
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:95602	Fyn	involved_in	GO:0018108	PMID:27525436	IMP		P	Tyrosine-protein kinase Fyn		protein	taxon:10090	20180509	ARUK-UCL	has_input(UniProtKB:Q9JHI8),occurs_in(UBERON:0000948),negatively_regulates(GO:1903409)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:95602	Fyn	involved_in	GO:0050730	PMID:22820466	IGI	UniProtKB:P04925	P	Tyrosine-protein kinase Fyn		protein	taxon:10090	20230517	ARUK-UCL	occurs_in(CL:0010012),part_of(GO:1904645),has_input(UniProtKB:Q01097)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:99606	Abca2	acts_upstream_of	GO:1905598	PMID:21810484	IDA		P	ATP-binding cassette sub-family A member 2		protein	taxon:10090	20190726	ARUK-UCL	occurs_in(CL:0000540)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:99779	Chrna7	involved_in	GO:0001933	PMID:19230830	IDA		P	Neuronal acetylcholine receptor subunit alpha-7		protein	taxon:10090	20170110	ARUK-UCL	has_input(UniProtKB:P10637),occurs_in(UBERON:0000955),regulates(GO:0009409)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:99779	Chrna7	involved_in	GO:0001934	PMID:17898229	IDA		P	Neuronal acetylcholine receptor subunit alpha-7		protein	taxon:10090	20170109	ARUK-UCL	occurs_in(UBERON:0003027)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:99779	Chrna7	involved_in	GO:0033138	PMID:19230830	IMP		P	Neuronal acetylcholine receptor subunit alpha-7		protein	taxon:10090	20170110	ARUK-UCL	has_input(UniProtKB:P49841),occurs_in(UBERON:0003027)|has_input(UniProtKB:P49841),occurs_in(UBERON:0001885)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:99779	Chrna7	involved_in	GO:1905920	PMID:20164328	IGI	UniProtKB:P05067	P	Neuronal acetylcholine receptor subunit alpha-7		protein	taxon:10090	20170208	ARUK-UCL	has_input(UniProtKB:P12023),happens_during(UBERON:0018241),occurs_in(UBERON:0002421),has_input(UniProtKB:Q03059)|has_input(UniProtKB:P12023),happens_during(UBERON:0018241),occurs_in(UBERON:0002743),has_input(UniProtKB:Q03059)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:101765	Cdk5	involved_in	GO:0018105	PMID:24607229	IMP		P	Cyclin-dependent kinase 5		protein	taxon:10090	20171030	ARUK-UCL	has_input(UniProtKB:Q01097),occurs_in(UBERON:0002421),regulates(GO:0072659)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:101765	Cdk5	involved_in	GO:0018107	PMID:24607229	IMP		P	Cyclin-dependent kinase 5		protein	taxon:10090	20171030	ARUK-UCL	has_input(UniProtKB:Q60829),occurs_in(UBERON:0002421)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:99611	Ephb2	acts_upstream_of	GO:0006469	PMID:11585923	IDA		P	Ephrin type-B receptor 2		protein	taxon:10090	20210421	ARUK-UCL		
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:99611	Ephb2	involved_in	GO:0001933	PMID:11585923	IDA		P	Ephrin type-B receptor 2		protein	taxon:10090	20170620	ARUK-UCL	negatively_regulates(GO:0004708)|negatively_regulates(GO:0070371)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:99611	Ephb2	involved_in	GO:0018108	PMID:21113149	IMP		P	Ephrin type-B receptor 2		protein	taxon:10090	20170620	ARUK-UCL	has_input(UniProtKB:P35438)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:99611	Ephb2	involved_in	GO:1904782	PMID:21113149	IMP		P	Ephrin type-B receptor 2		protein	taxon:10090	20170620	ARUK-UCL	causally_upstream_of(GO:1900272),occurs_in(CL:2000089)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:99611	Ephb2	involved_in	GO:1904783	PMID:21113149	IMP		P	Ephrin type-B receptor 2		protein	taxon:10090	20170620	ARUK-UCL	causally_upstream_of(GO:1900273),occurs_in(CL:2000089)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:107926	Rock2	involved_in	GO:0018107	PMID:29353861	IMP		P	Rho-associated protein kinase 2		protein	taxon:10090	20181204	ARUK-UCL	causally_upstream_of(GO:0050115),occurs_in(CL:2000044)|causally_upstream_of(GO:0050115),occurs_in(CL:0010008)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:107926	Rock2	involved_in	GO:0018107	PMID:29353861	IMP		P	Rho-associated protein kinase 2		protein	taxon:10090	20181204	ARUK-UCL	has_input(UniProtKB:P10126),occurs_in(CL:2000044),part_of(GO:0061157)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:107956	Slc8a1	acts_upstream_of_or_within	GO:0071901	PMID:29274751	IMP		P	Sodium/calcium exchanger 1		protein	taxon:10090	20191210	ARUK-UCL	occurs_in(UBERON:0002421),has_input(UniProtKB:Q9UQM7)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:2442092	Wnk1	acts_upstream_of	GO:0018107	PMID:27782176	IMP		P	Serine/threonine-protein kinase WNK1		protein	taxon:10090	20200119	ARUK-UCL	has_input(UniProtKB:Q924N4)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1349394	Map4k4	involved_in	GO:0043547	PMID:25490267	IMP		P	Mitogen-activated protein kinase kinase kinase kinase 4		protein	taxon:10090	20180627	ARUK-UCL	occurs_in(CL:0000312),has_input(UniProtKB:P62331)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:98277	Epha4	involved_in	GO:0061098	PMID:24658113	IGI	ComplexPortal:CPX-1134	P	Ephrin type-A receptor 4		protein	taxon:10090	20170627	ARUK-UCL	occurs_in(CL:0002608),has_input(UniProtKB:P00520)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1341865	Mark3	involved_in	GO:0018105	PMID:9543386	ISS	UniProtKB:P27448	P	MAP/microtubule affinity-regulating kinase 3		protein	taxon:10090	20180328	ARUK-UCL	has_input(UniProtKB:P48967),positively_regulates(GO:0005515)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1341865	Mark3	involved_in	GO:0036289	PMID:9543386	ISS	UniProtKB:P27448	P	MAP/microtubule affinity-regulating kinase 3		protein	taxon:10090	20180328	ARUK-UCL	has_input(UniProtKB:Q03141)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:2444243	Map3k13	involved_in	GO:0018105	PMID:27511108	IMP		P	Mitogen-activated protein kinase kinase kinase 13		protein	taxon:10090	20180716	ARUK-UCL	has_input(UniProtKB:P45985),occurs_in(CL:0000540)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:2444243	Map3k13	involved_in	GO:0043507	PMID:27511108	IMP		P	Mitogen-activated protein kinase kinase kinase 13		protein	taxon:10090	20210421	ARUK-UCL	has_input(UniProtKB:Q9WTU6),occurs_in(CL:0000540)|has_input(UniProtKB:Q91Y86),occurs_in(CL:0000540)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:2444243	Map3k13	involved_in	GO:0045860	PMID:27511108	IMP		P	Mitogen-activated protein kinase kinase kinase 13		protein	taxon:10090	20210421	ARUK-UCL	has_input(UniProtKB:P47809),occurs_in(CL:0000540)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:2152453	Gsk3a	involved_in	GO:0018105	PMID:16537926	IGI	UniProtKB:Q9WV60	P	Glycogen synthase kinase-3 alpha		protein	taxon:10090	20171018	ARUK-UCL	has_input(UniProtKB:Q8VI36)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:2145955	Prkaa1	involved_in	GO:2000758	PMID:27430620	IGI	UniProtKB:Q8BRK8	P	5'-AMP-activated protein kinase catalytic subunit alpha-1		protein	taxon:10090	20180309	ARUK-UCL	part_of(GO:0034599),has_input(UniProtKB:P68369)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1346881	Map3k12	involved_in	GO:0018105	PMID:27511108	IMP		P	Mitogen-activated protein kinase kinase kinase 12		protein	taxon:10090	20180716	ARUK-UCL	has_input(UniProtKB:P47809),occurs_in(CL:0000540)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1346881	Map3k12	involved_in	GO:0043507	PMID:27511108	IMP		P	Mitogen-activated protein kinase kinase kinase 12		protein	taxon:10090	20210421	ARUK-UCL	has_input(UniProtKB:Q9WTU6),occurs_in(CL:0000540)|has_input(UniProtKB:Q91Y86),occurs_in(CL:0000540)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1346881	Map3k12	involved_in	GO:0045860	PMID:27511108	IMP		P	Mitogen-activated protein kinase kinase kinase 12		protein	taxon:10090	20210421	ARUK-UCL	has_input(UniProtKB:P47809),occurs_in(CL:0000540)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1330299	Dyrk1a	involved_in	GO:0038083	PMID:24327345	IDA		P	Dual specificity tyrosine-phosphorylation-regulated kinase 1A		protein	taxon:10090	20171205	ARUK-UCL	occurs_in(GO:0005829)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:99879	Prkd1	acts_upstream_of	GO:0018107	PMID:27782176	IMP		P	Serine/threonine-protein kinase D1		protein	taxon:10090	20200119	ARUK-UCL	has_input(UniProtKB:Q924N4)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:104574	Ptprj	involved_in	GO:0050731	PMID:18249142	IGI	UniProtKB:P06800	P	Receptor-type tyrosine-protein phosphatase eta		protein	taxon:10090	20180725	ARUK-UCL	has_input(UniProtKB:P25911)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:2147036	Ttbk1	involved_in	GO:0018105	PMID:16923168	ISS	UniProtKB:Q5TCY1	P	Tau-tubulin kinase 1		protein	taxon:10090	20190619	ARUK-UCL	has_input(UniProtKB:P10637),positively_regulates(GO:0051258)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:2147036	Ttbk1	involved_in	GO:0018107	PMID:16923168	ISS	UniProtKB:Q5TCY1	P	Tau-tubulin kinase 1		protein	taxon:10090	20190619	ARUK-UCL	has_input(UniProtKB:P10637),positively_regulates(GO:0051258)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:2147036	Ttbk1	involved_in	GO:0018108	PMID:16923168	ISS	UniProtKB:Q5TCY1	P	Tau-tubulin kinase 1		protein	taxon:10090	20190619	ARUK-UCL	has_input(UniProtKB:P10637)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1861431	Clec7a	acts_upstream_of_or_within	GO:0051091	PMID:19136564	IMP		P	C-type lectin domain family 7 member A		protein	taxon:10090	20210416	ARUK-UCL	occurs_in(CL:0000451),has_input(UniProtKB:P05627),part_of(GO:0001878)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1861431	Clec7a	acts_upstream_of_or_within	GO:0051091	PMID:19136564	IMP		P	C-type lectin domain family 7 member A		protein	taxon:10090	20210416	ARUK-UCL	occurs_in(CL:0000451),has_input(UniProtKB:P97305),part_of(GO:0001878)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1861431	Clec7a	acts_upstream_of_or_within	GO:0051091	PMID:19136564	IMP		P	C-type lectin domain family 7 member A		protein	taxon:10090	20210416	ARUK-UCL	occurs_in(CL:0000451),has_input(UniProtKB:Q60591),part_of(GO:0001878)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1861431	Clec7a	involved_in	GO:0051092	PMID:19136564	IDA		P	C-type lectin domain family 7 member A		protein	taxon:10090	20210416	ARUK-UCL	occurs_in(CL:0000451),part_of(GO:0001878)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:2652875	Wnk3	acts_upstream_of	GO:0018107	PMID:27782176	IMP		P	Serine/threonine-protein kinase WNK3		protein	taxon:10090	20200119	ARUK-UCL	has_input(UniProtKB:Q924N4),causally_upstream_of(GO:1904062)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1336173	Prkaa2	involved_in	GO:2000758	PMID:27430620	IGI	UniProtKB:Q5EG47	P	5'-AMP-activated protein kinase catalytic subunit alpha-2		protein	taxon:10090	20180309	ARUK-UCL	part_of(GO:0034599),has_input(UniProtKB:P68369)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:2385110	Aph1a	involved_in	GO:0010950	PMID:12522139	IMP		P	Gamma-secretase subunit APH-1A		protein	taxon:10090	20201110	ARUK-UCL	has_input(UniProtKB:P49769)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:97616	Plcg2	acts_upstream_of_or_within	GO:0051091	PMID:19136564	IMP		P	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2		protein	taxon:10090	20210416	ARUK-UCL	occurs_in(CL:0000451),part_of(GO:1990858),has_input(UniProtKB:P05627)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:97616	Plcg2	acts_upstream_of_or_within	GO:0051091	PMID:19136564	IMP		P	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2		protein	taxon:10090	20210416	ARUK-UCL	occurs_in(CL:0000451),part_of(GO:1990858),has_input(UniProtKB:P97305)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:97616	Plcg2	acts_upstream_of_or_within	GO:0051091	PMID:19136564	IMP		P	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2		protein	taxon:10090	20210416	ARUK-UCL	occurs_in(CL:0000451),part_of(GO:1990858),has_input(UniProtKB:Q60591)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:97616	Plcg2	involved_in	GO:0050731	PMID:22041900	IMP		P	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2		protein	taxon:10090	20210416	ARUK-UCL	occurs_in(CL:0000235),has_input(UniProtKB:P63085),part_of(GO:0043410)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:97616	Plcg2	involved_in	GO:0050731	PMID:22041900	IMP		P	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2		protein	taxon:10090	20210416	ARUK-UCL	occurs_in(CL:0000235),has_input(UniProtKB:Q9WTU6),part_of(GO:0043410)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:97616	Plcg2	involved_in	GO:0051092	PMID:19136564	IMP		P	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2		protein	taxon:10090	20210416	ARUK-UCL	occurs_in(CL:0000451),part_of(GO:1990858)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:97616	Plcg2	involved_in	GO:1903721	PMID:22041900	IMP		P	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2		protein	taxon:10090	20210416	ARUK-UCL	occurs_in(CL:0000235),part_of(GO:0043122)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:107996	Slc8a2	acts_upstream_of_or_within	GO:0071902	PMID:29274751	IMP		P	Sodium/calcium exchanger 2		protein	taxon:10090	20191210	ARUK-UCL	occurs_in(UBERON:0002421),has_input(UniProtKB:Q9UQM7)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:106271	Mapre2	involved_in	GO:0043547	PMID:25490267	IMP		P	Microtubule-associated protein RP/EB family member 2		protein	taxon:10090	20180627	ARUK-UCL	occurs_in(CL:0000312),has_input(UniProtKB:P62331)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:2385228	Tmem119	involved_in	GO:0001934	PMID:22579779	IDA		P	Transmembrane protein 119		protein	taxon:10090	20190308	ARUK-UCL	occurs_in(GO:0071144)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1913150	Trem2	involved_in	GO:0001934	PMID:29518356	IGI	ComplexPortal:CPX-1120	P	Triggering receptor expressed on myeloid cells 2		protein	taxon:10090	20181212	ARUK-UCL	occurs_in(CL:0000129),has_input(UniProtKB:Q9WV60)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1913150	Trem2	involved_in	GO:0050730	PMID:29518356	IGI	ComplexPortal:CPX-1120	P	Triggering receptor expressed on myeloid cells 2		protein	taxon:10090	20181212	ARUK-UCL	occurs_in(CL:0000129),has_input(UniProtKB:P48025)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1913150	Trem2	involved_in	GO:1901980	PMID:29518356	IMP		P	Triggering receptor expressed on myeloid cells 2		protein	taxon:10090	20181212	ARUK-UCL	occurs_in(CL:0000129)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1913590	Psenen	involved_in	GO:0010950	PMID:12522139	IMP		P	Gamma-secretase subunit PEN-2		protein	taxon:10090	20201110	ARUK-UCL	has_input(UniProtKB:P49769)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1859852	Hes6	involved_in	GO:0043433	PMID:10851137	IDA		P	Transcription cofactor HES-6		protein	taxon:10090	20200505	ARUK-UCL	has_input(UniProtKB:P35428)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1354184	Nox4	involved_in	GO:0061098	PMID:27525436	IDA		P	NADPH oxidase 4		protein	taxon:10090	20230605	ARUK-UCL	occurs_in(CL:0000746),has_input(UniProtKB:P39688),part_of(GO:0006979)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1861231	Clec6a	acts_upstream_of	GO:0050731	PMID:22041900	IMP		P	C-type lectin domain family 6 member A		protein	taxon:10090	20210416	ARUK-UCL	has_input(UniProtKB:P48025),occurs_in(CL:0000235),part_of(GO:1902533)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1858226	Slc5a3	acts_upstream_of_or_within	GO:0043085	PMID:28128227	IMP		P	Sodium/myo-inositol cotransporter		protein	taxon:10090	20200329	ARUK-UCL	occurs_in(CL:0000746),has_input(UniProtKB:Q61093)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1861437	Gsk3b	involved_in	GO:0018105	PMID:16537926	IGI	UniProtKB:Q2NL51	P	Glycogen synthase kinase-3 beta		protein	taxon:10090	20171018	ARUK-UCL	has_input(UniProtKB:Q8VI36)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1858416	Stk39	involved_in	GO:0018107	PMID:27782176	IMP		P	STE20/SPS1-related proline-alanine-rich protein kinase		protein	taxon:10090	20200119	ARUK-UCL	has_input(UniProtKB:Q924N4)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1333752	Hdac6	involved_in	GO:0033138	PMID:23962722	IMP		P	Histone deacetylase 6		protein	taxon:10090	20180126	ARUK-UCL	has_input(UniProtKB:P10637)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1333752	Hdac6	involved_in	GO:0034983	PMID:23962722	IMP		P	Histone deacetylase 6		protein	taxon:10090	20180126	ARUK-UCL	has_input(UniProtKB:P10637)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:107976	Slc8a3	acts_upstream_of_or_within	GO:0071901	PMID:29274751	IMP		P	Sodium/calcium exchanger 3		protein	taxon:10090	20191210	ARUK-UCL	occurs_in(UBERON:0002421),has_input(UniProtKB:Q9UQM7)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05027	ATP1B1	involved_in	GO:1903408	PMID:18052210	IGI	UniProtKB:P05023	P	Sodium/potassium-transporting ATPase subunit beta-1	ATP1B1	protein	taxon:9823	20200717	ARUK-UCL		UniProtKB:P05027
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O00206	TLR4	acts_upstream_of	GO:0051092	PMID:30233718	IMP		P	Toll-like receptor 4	TLR4	protein	taxon:9606	20201102	ARUK-UCL		UniProtKB:O00206
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O00410	IPO5	involved_in	GO:0045736	PMID:17491008	TAS		P	Importin-5	IPO5|KPNB3|RANBP5	protein	taxon:9606	20171030	ARUK-UCL	has_input(UniProtKB:Q00535)	UniProtKB:O00410
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O00499	BIN1	involved_in	GO:1902960	PMID:27179792	IMP		P	Myc box-dependent-interacting protein 1	BIN1|AMPHL	protein	taxon:9606	20190717	ARUK-UCL	has_output(UniProtKB:P05067-PRO_0000000093),has_input(UniProtKB:P56817)|has_output(UniProtKB:P05067-PRO_0000000092),has_input(UniProtKB:P56817)	UniProtKB:O00499
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O14493	CLDN4	involved_in	GO:1905050	PMID:16103090	IMP		P	Claudin-4	CLDN4|CPER|CPETR1|WBSCR8	protein	taxon:9606	20190912	ARUK-UCL	occurs_in(CL:2000064),has_input(UniProtKB:P08253)	UniProtKB:O14493
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O14522	PTPRT	involved_in	GO:0035335	PMID:17360477	IDA		P	Receptor-type tyrosine-protein phosphatase T	PTPRT|KIAA0283	protein	taxon:9606	20180803	ARUK-UCL	has_input(UniProtKB:P40763),part_of(GO:1904893)	UniProtKB:O14522
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O14522	PTPRT	involved_in	GO:1990264	PMID:24846175	IDA		P	Receptor-type tyrosine-protein phosphatase T	PTPRT|KIAA0283	protein	taxon:9606	20180803	ARUK-UCL		UniProtKB:O14522
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O15551	CLDN3	involved_in	GO:0001934	PMID:27593915	IMP		P	Claudin-3	CLDN3|C7orf1|CPETR2	protein	taxon:9606	20211119	ARUK-UCL	occurs_in(CL:0002586)	UniProtKB:O15551
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O15551	CLDN3	involved_in	GO:1905050	PMID:16103090	IMP		P	Claudin-3	CLDN3|C7orf1|CPETR2	protein	taxon:9606	20190912	ARUK-UCL	occurs_in(CL:2000064),has_input(UniProtKB:P08253)	UniProtKB:O15551
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O43283	MAP3K13	involved_in	GO:0043507	GO_REF:0000024	ISS	UniProtKB:Q1HKZ5	P	Mitogen-activated protein kinase kinase kinase 13	MAP3K13|LZK	protein	taxon:9606	20210421	ARUK-UCL	has_input(UniProtKB:P45984),occurs_in(CL:0000540)|has_input(UniProtKB:P45983),occurs_in(CL:0000540)	UniProtKB:O43283
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O43283	MAP3K13	involved_in	GO:0043507	GO_REF:0000024	ISS	UniProtKB:Q1HKZ5	P	Mitogen-activated protein kinase kinase kinase 13	MAP3K13|LZK	protein	taxon:9606	20210421	ARUK-UCL	has_input(UniProtKB:Q9WTU6),occurs_in(CL:0000540)|has_input(UniProtKB:Q91Y86),occurs_in(CL:0000540)	UniProtKB:O43283
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O43504	LAMTOR5	acts_upstream_of_or_within	GO:0051092	PMID:21343296	IGI	UniProtKB:Q04206	P	Ragulator complex protein LAMTOR5	LAMTOR5|HBXIP|XIP	protein	taxon:9606	20191029	ARUK-UCL	has_input(UniProtKB:P10145)	UniProtKB:O43504
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O76096	CST7	involved_in	GO:0010466	PMID:15752368	IDA		P	Cystatin-F	CST7	protein	taxon:9606	20190227	ARUK-UCL	has_input(UniProtKB:P00784),has_input(UniProtKB:Q9UBX1),has_input(UniProtKB:P43235),has_input(UniProtKB:O60911),has_input(UniProtKB:P09668),has_input(UniProtKB:P25774)	UniProtKB:O76096
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O76096	CST7	involved_in	GO:0010466	PMID:18256700	IDA		P	Cystatin-F	CST7	protein	taxon:9606	20190227	ARUK-UCL	has_input(UniProtKB:P07711),has_input(UniProtKB:P53634)	UniProtKB:O76096
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O76096	CST7	involved_in	GO:0010466	PMID:22365146	IDA		P	Cystatin-F	CST7	protein	taxon:9606	20190430	ARUK-UCL	has_input(UniProtKB:P09668)|has_input(UniProtKB:P07711)|has_input(UniProtKB:P25774)	UniProtKB:O76096
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O95373	IPO7	involved_in	GO:0045736	PMID:17491008	TAS		P	Importin-7	IPO7|RANBP7	protein	taxon:9606	20171030	ARUK-UCL	has_input(UniProtKB:Q00535)	UniProtKB:O95373
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O95816	BAG2	involved_in	GO:1904667	PMID:16207813	IDA		P	BAG family molecular chaperone regulator 2	BAG2	protein	taxon:9606	20180305	ARUK-UCL	has_input(UniProtKB:Q9UNE7)	UniProtKB:O95816
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O95819	MAP4K4	involved_in	GO:0043547	PMID:25490267	ISS	UniProtKB:P97820	P	Mitogen-activated protein kinase kinase kinase kinase 4	MAP4K4|HGK|KIAA0687|NIK	protein	taxon:9606	20180719	ARUK-UCL	occurs_in(CL:0000312),has_input(UniProtKB:P62330)	UniProtKB:O95819
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P00973	OAS1	involved_in	GO:0060700	PMID:25275129	IDA		P	2'-5'-oligoadenylate synthase 1	OAS1|OIAS	protein	taxon:9606	20210215	ARUK-UCL	part_of(GO:0051607)	UniProtKB:P00973
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P01034	CST3	involved_in	GO:0010466	PMID:18256700	IDA		P	Cystatin-C	CST3	protein	taxon:9606	20190227	ARUK-UCL	has_input(UniProtKB:P53634),has_input(UniProtKB:P07711)	UniProtKB:P01034
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P01375	TNF	acts_upstream_of_or_within	GO:1903721	PMID:31124343	IDA		P	Tumor necrosis factor	TNF|TNFA|TNFSF2	protein	taxon:9606	20200210	ARUK-UCL	occurs_in(CL:0000214),part_of(GO:1901224)	UniProtKB:P01375
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P01579	IFNG	involved_in	GO:1904783	GO_REF:0000024	ISS	UniProtKB:P01581	P	Interferon gamma	IFNG	protein	taxon:9606	20190318	ARUK-UCL	occurs_in(CL:0000540),occurs_in(UBERON:0002181),occurs_in(CL:0000129)	UniProtKB:P01579
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P02786	TFRC	involved_in	GO:0001934	PMID:23016877	IMP	ComplexPortal:CPX-3269	P	Transferrin receptor protein 1	TFRC	protein	taxon:9606	20191126	ARUK-UCL	occurs_in(CL:0000066)	UniProtKB:P02786
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P02786	TFRC	involved_in	GO:0033138	PMID:23016877	IMP	UniProtKB:Q04206	P	Transferrin receptor protein 1	TFRC	protein	taxon:9606	20191127	ARUK-UCL	occurs_in(CL:0000066)	UniProtKB:P02786
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P02786	TFRC	involved_in	GO:0051092	PMID:23016877	IMP		P	Transferrin receptor protein 1	TFRC	protein	taxon:9606	20191126	ARUK-UCL	occurs_in(CL:0000066)	UniProtKB:P02786
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P04156	PRNP	involved_in	GO:0050730	GO_REF:0000024	ISS	UniProtKB:P04925	P	Major prion protein	PRNP|ALTPRP|PRIP|PRP	protein	taxon:9606	20230517	ARUK-UCL	occurs_in(CL:0010012),part_of(GO:1904645),has_input(UniProtKB:Q13224)	UniProtKB:P04156
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P04156	PRNP	involved_in	GO:0050731	PMID:22820466	IDA		P	Major prion protein	PRNP|ALTPRP|PRIP|PRP	protein	taxon:9606	20230517	ARUK-UCL	occurs_in(CL:0010012),part_of(GO:1904645),has_input(UniProtKB:P39688)	UniProtKB:P04156
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05019	IGF1	involved_in	GO:0050731	PMID:22635104	IDA		P	Insulin-like growth factor 1	IGF1|IBP1|IGF-1	protein	taxon:9606	20170906	ARUK-UCL	occurs_in(CL:0000540),has_input(UniProtKB:P08069),occurs_in(GO:0005886)	UniProtKB:P05019
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05026	ATP1B1	involved_in	GO:1903408	PMID:10636900	IDA		P	Sodium/potassium-transporting ATPase subunit beta-1	ATP1B1|ATP1B	protein	taxon:9606	20200717	ARUK-UCL		UniProtKB:P05026
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05026	ATP1B1	involved_in	GO:1903408	PMID:18728015	IGI	UniProtKB:P50993	P	Sodium/potassium-transporting ATPase subunit beta-1	ATP1B1|ATP1B	protein	taxon:9606	20200717	ARUK-UCL	occurs_in(GO:0005886),part_of(GO:1903408),has_input(UniProtKB:P50993)	UniProtKB:P05026
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05026	ATP1B1	involved_in	GO:1903408	PMID:20100892	IGI	UniProtKB:P50993	P	Sodium/potassium-transporting ATPase subunit beta-1	ATP1B1|ATP1B	protein	taxon:9606	20200717	ARUK-UCL	occurs_in(GO:0005886),part_of(GO:1903408),has_input(UniProtKB:P50993)	UniProtKB:P05026
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05026	ATP1B1	involved_in	GO:1903408	PMID:20100892	IGI	UniProtKB:Q13733	P	Sodium/potassium-transporting ATPase subunit beta-1	ATP1B1|ATP1B	protein	taxon:9606	20200717	ARUK-UCL	occurs_in(CL:0000019),part_of(GO:1903408),has_input(UniProtKB:Q13733)	UniProtKB:P05026
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05026	ATP1B1	involved_in	GO:1903408	PMID:23954377	IDA		P	Sodium/potassium-transporting ATPase subunit beta-1	ATP1B1|ATP1B	protein	taxon:9606	20200717	ARUK-UCL		UniProtKB:P05026
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05067	APP	NOT|involved_in	GO:0050731	PMID:22635104	IDA		P	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20170906	ARUK-UCL		UniProtKB:P05067-PRO_0000000092
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05067	APP	involved_in	GO:0001934	PMID:11404397	IDA		P	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20170210	ARUK-UCL	occurs_in(UBERON:0001885),has_input(UniProtKB:P16220)|occurs_in(UBERON:0003881),has_input(UniProtKB:P16220),happens_during(UBERON:0018241)	UniProtKB:P05067
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05067	APP	involved_in	GO:0001934	PMID:11404397	IDA		P	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20170210	ARUK-UCL	occurs_in(UBERON:0001885),has_input(UniProtKB:P28482),happens_during(UBERON:0018241)|occurs_in(UBERON:0003881),has_input(UniProtKB:P28482),happens_during(UBERON:0018241)	UniProtKB:P05067
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05067	APP	involved_in	GO:0001934	PMID:15457210	IGI	UniProtKB:Q15109	P	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20170928	ARUK-UCL	happens_during(UBERON:0007222),positively_regulates(GO:0004683),occurs_in(UBERON:0002421)	UniProtKB:P05067
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05067	APP	involved_in	GO:0001934	PMID:15457210	IGI	UniProtKB:Q15109	P	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20170928	ARUK-UCL	has_input(UniProtKB:Q16539),happens_during(UBERON:0018241)	UniProtKB:P05067
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05067	APP	involved_in	GO:0001934	PMID:15457210	IGI	UniProtKB:Q15109	P	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20170928	ARUK-UCL	part_of(GO:0032793),happens_during(UBERON:0018241)	UniProtKB:P05067
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05067	APP	involved_in	GO:0001934	PMID:20141570	IDA		P	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20240201	ARUK-UCL	occurs_in(CL:0000127)|occurs_in(CL:0000129)	UniProtKB:P05067-PRO_0000000092
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05067	APP	involved_in	GO:0010800	PMID:19660551	IMP		P	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20230322	ARUK-UCL	occurs_in(UBERON:0002421),has_input(UniProtKB:P10636)|occurs_in(UBERON:0000956),has_input(UniProtKB:P10636)	UniProtKB:P05067
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05067	APP	involved_in	GO:0033138	PMID:19660551	IMP		P	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20230322	ARUK-UCL	occurs_in(UBERON:0002421),has_input(UniProtKB:P10636)|occurs_in(UBERON:0000956),has_input(UniProtKB:P10636)	UniProtKB:P05067
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05067	APP	involved_in	GO:0050730	PMID:21857966	IGI	UniProtKB:P49768	P	Amyloid-beta precursor protein	APP|A4|AD1	protein	taxon:9606	20171220	ARUK-UCL	has_input(UniProtKB:Q9UQM7)	UniProtKB:P05067
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05107	ITGB2	involved_in	GO:2000363	PMID:18981141	NAS		P	Integrin beta-2	ITGB2|CD18|MFI7	protein	taxon:9606	20210429	ARUK-UCL	occurs_in(UBERON:0001891),occurs_in(CL:0000125),has_output(CHEBI:15551),part_of(GO:0033554)	UniProtKB:P05107
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05556	ITGB1	acts_upstream_of_or_within	GO:1901979	GO_REF:0000024	ISS	UniProtKB:P09055	P	Integrin beta-1	ITGB1|FNRB|MDF2|MSK12	protein	taxon:9606	20200116	ARUK-UCL	occurs_in(UBERON:0003528),occurs_in(CL:0000127)	UniProtKB:P05556
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P06213	INSR	involved_in	GO:0006468	PMID:19188609	TAS		P	Insulin receptor	INSR	protein	taxon:9606	20170523	ARUK-UCL	has_input(UniProtKB:P10636)	UniProtKB:P06213
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P06239	LCK	involved_in	GO:0018108	PMID:11606584	IMP		P	Tyrosine-protein kinase Lck	LCK	protein	taxon:9606	20210216	ARUK-UCL	has_input(UniProtKB:P16885),part_of(GO:0035556)	UniProtKB:P06239
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P06241	FYN	involved_in	GO:0018108	PMID:11606584	IMP		P	Tyrosine-protein kinase Fyn	FYN	protein	taxon:9606	20210216	ARUK-UCL	has_input(UniProtKB:P16885),part_of(GO:0035556)	UniProtKB:P06241
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P06241	FYN	involved_in	GO:0018108	PMID:27520374	IMP		P	Tyrosine-protein kinase Fyn	FYN	protein	taxon:9606	20181219	ARUK-UCL	occurs_in(CL:0000540),has_input(UniProtKB:P10636),part_of(GO:1904646)	UniProtKB:P06241
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P06241	FYN	involved_in	GO:0018108	PMID:27525436	ISS	UniProtKB:Q62844	P	Tyrosine-protein kinase Fyn	FYN	protein	taxon:9606	20180509	ARUK-UCL	has_input(UniProtKB:Q9NPH5),occurs_in(CL:0000746),negatively_regulates(GO:1903409)	UniProtKB:P06241
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P06241	FYN	involved_in	GO:0050730	GO_REF:0000024	ISS	UniProtKB:P39688	P	Tyrosine-protein kinase Fyn	FYN	protein	taxon:9606	20230517	ARUK-UCL	occurs_in(CL:0010012),part_of(GO:1904645),has_input(UniProtKB:Q13224)	UniProtKB:P06241
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P06400	RB1	involved_in	GO:0071901	PMID:24027266	ISS	UniProtKB:P33568	P	Retinoblastoma-associated protein	RB1	protein	taxon:9606	20190307	ARUK-UCL	occurs_in(CL:0010012),has_input(UniProtKB:Q00535),has_input(UniProtKB:P10636)	UniProtKB:P06400
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P06400	RB1	involved_in	GO:1902948	PMID:24027266	ISS	UniProtKB:P33568	P	Retinoblastoma-associated protein	RB1	protein	taxon:9606	20190307	ARUK-UCL	occurs_in(CL:0010012),has_input(UniProtKB:Q00535),has_input(UniProtKB:P10636)	UniProtKB:P06400
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P06727	APOA4	involved_in	GO:1905920	PMID:1935934	IDA		P	Apolipoprotein A-IV	APOA4	protein	taxon:9606	20220217	ARUK-UCL		UniProtKB:P06727
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P07948	LYN	involved_in	GO:0001934	PMID:24217950	IGI	UniProtKB:P20827	P	Tyrosine-protein kinase Lyn	LYN|JTK8	protein	taxon:9606	20170621	ARUK-UCL	has_input(UniProtKB:P54764)	UniProtKB:P07948
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P07948	LYN	involved_in	GO:1902961	PMID:24217950	IMP		P	Tyrosine-protein kinase Lyn	LYN|JTK8	protein	taxon:9606	20170621	ARUK-UCL		UniProtKB:P07948
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P08575	PTPRC	involved_in	GO:0050731	GO_REF:0000024	ISS	UniProtKB:P06800	P	Receptor-type tyrosine-protein phosphatase C	PTPRC|CD45	protein	taxon:9606	20180725	ARUK-UCL	has_input(UniProtKB:P07948)	UniProtKB:P08575
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P0DP24	CALM2	involved_in	GO:1901020	GO_REF:0000024	ISS	UniProtKB:P0DP27	P	Calmodulin-2	CALM2|CAM2|CAMB	protein	taxon:9606	20210421	ARUK-UCL	has_input(UniProtKB:Q8NFF2),causally_upstream_of(GO:0050848)	UniProtKB:P0DP24
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P11215	ITGAM	involved_in	GO:2000363	GO_REF:0000024	ISS	UniProtKB:P05555	P	Integrin alpha-M	ITGAM|CD11B|CR3A	protein	taxon:9606	20230605	ARUK-UCL	occurs_in(UBERON:0001891),occurs_in(CL:0000125),has_output(CHEBI:15551),part_of(GO:0033554)|occurs_in(UBERON:0001891),occurs_in(CL:0000540),has_output(CHEBI:15551),part_of(GO:0033554)	UniProtKB:P11215
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P12931	SRC	involved_in	GO:0018108	PMID:11606584	IMP		P	Proto-oncogene tyrosine-protein kinase Src	SRC|SRC1	protein	taxon:9606	20210216	ARUK-UCL	has_input(UniProtKB:P16885),part_of(GO:0035556)	UniProtKB:P12931
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P12931	SRC	involved_in	GO:0050731	PMID:26598555	IMP		P	Proto-oncogene tyrosine-protein kinase Src	SRC|SRC1	protein	taxon:9606	20190517	ARUK-UCL	has_input(UniProtKB:P33151),occurs_in(CL:1001220)	UniProtKB:P12931
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P12931	SRC	involved_in	GO:0050731	PMID:26706435	IMP		P	Proto-oncogene tyrosine-protein kinase Src	SRC|SRC1	protein	taxon:9606	20211119	ARUK-UCL	has_input(UniProtKB:Q13480),occurs_in(CL:0002618)	UniProtKB:P12931
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P13500	CCL2	involved_in	GO:1904783	GO_REF:0000024	ISS	UniProtKB:P14844	P	C-C motif chemokine 2	CCL2|MCP1|SCYA2	protein	taxon:9606	20190318	ARUK-UCL	occurs_in(CL:0000540),occurs_in(UBERON:0002181)	UniProtKB:P13500
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P16284	PECAM1	involved_in	GO:0001934	PMID:15985432	IMP		P	Platelet endothelial cell adhesion molecule	PECAM1	protein	taxon:9606	20190603	ARUK-UCL	occurs_in(CL:0002618),has_input(UniProtKB:P27361)|occurs_in(CL:0002618),has_input(UniProtKB:P28482)|occurs_in(CL:0002618),has_input(UniProtKB:P29474)|occurs_in(CL:0002618),has_input(UniProtKB:Q02763)	UniProtKB:P16284
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P16284	PECAM1	involved_in	GO:0001934	PMID:26706435	IMP		P	Platelet endothelial cell adhesion molecule	PECAM1	protein	taxon:9606	20190531	ARUK-UCL	has_input(UniProtKB:P29474),occurs_in(CL:0002618)	UniProtKB:P16284
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P16284	PECAM1	involved_in	GO:0050731	PMID:26706435	IMP		P	Platelet endothelial cell adhesion molecule	PECAM1	protein	taxon:9606	20211119	ARUK-UCL	has_input(UniProtKB:Q13480),occurs_in(CL:0002618)	UniProtKB:P16284
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P16885	PLCG2	acts_upstream_of_or_within	GO:0051091	GO_REF:0000024	ISS	UniProtKB:Q8CIH5	P	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2	PLCG2	protein	taxon:9606	20210416	ARUK-UCL	occurs_in(CL:0000451),part_of(GO:1990858),has_input(UniProtKB:P05412)	UniProtKB:P16885
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P16885	PLCG2	acts_upstream_of_or_within	GO:0051091	GO_REF:0000024	ISS	UniProtKB:Q8CIH5	P	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2	PLCG2	protein	taxon:9606	20210416	ARUK-UCL	occurs_in(CL:0000451),part_of(GO:1990858),has_input(UniProtKB:Q12968)	UniProtKB:P16885
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P16885	PLCG2	acts_upstream_of_or_within	GO:0051091	GO_REF:0000024	ISS	UniProtKB:Q8CIH5	P	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2	PLCG2	protein	taxon:9606	20210416	ARUK-UCL	occurs_in(CL:0000451),part_of(GO:1990858),has_input(UniProtKB:Q13469)	UniProtKB:P16885
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P16885	PLCG2	involved_in	GO:0050731	GO_REF:0000024	ISS	UniProtKB:Q8CIH5	P	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2	PLCG2	protein	taxon:9606	20210416	ARUK-UCL	occurs_in(CL:0000235),has_input(UniProtKB:P28482),part_of(GO:0043410)	UniProtKB:P16885
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P16885	PLCG2	involved_in	GO:0050731	GO_REF:0000024	ISS	UniProtKB:Q8CIH5	P	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2	PLCG2	protein	taxon:9606	20210416	ARUK-UCL	occurs_in(CL:0000235),has_input(UniProtKB:P45984),part_of(GO:0043410)	UniProtKB:P16885
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P16885	PLCG2	involved_in	GO:0051091	GO_REF:0000024	ISS	UniProtKB:P24135	P	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2	PLCG2	protein	taxon:9606	20210216	ARUK-UCL	has_input(UniProtKB:P01100),occurs_in(CL:0000182),part_of(GO:1902808)	UniProtKB:P16885
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P16885	PLCG2	involved_in	GO:0051091	GO_REF:0000024	ISS	UniProtKB:P24135	P	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2	PLCG2	protein	taxon:9606	20210216	ARUK-UCL	has_input(UniProtKB:P01106),occurs_in(CL:0000182),part_of(GO:1902808)	UniProtKB:P16885
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P16885	PLCG2	involved_in	GO:0051091	GO_REF:0000024	ISS	UniProtKB:P24135	P	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2	PLCG2	protein	taxon:9606	20210216	ARUK-UCL	has_input(UniProtKB:P05412),occurs_in(CL:0000182),part_of(GO:1902808)	UniProtKB:P16885
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P16885	PLCG2	involved_in	GO:0051091	GO_REF:0000024	ISS	UniProtKB:P24135	P	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2	PLCG2	protein	taxon:9606	20210216	ARUK-UCL	has_input(UniProtKB:Q00653),occurs_in(CL:0000182),part_of(GO:1902808)	UniProtKB:P16885
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P16885	PLCG2	involved_in	GO:0051092	GO_REF:0000024	ISS	UniProtKB:Q8CIH5	P	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2	PLCG2	protein	taxon:9606	20210524	ARUK-UCL	occurs_in(CL:0000451),part_of(GO:1990840)	UniProtKB:P16885
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P16885	PLCG2	involved_in	GO:1903721	GO_REF:0000024	ISS	UniProtKB:Q8CIH5	P	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2	PLCG2	protein	taxon:9606	20210416	ARUK-UCL	occurs_in(CL:0000235),part_of(GO:0043122)	UniProtKB:P16885
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P17252	PRKCA	involved_in	GO:0018107	PMID:16717194	ISS	UniProtKB:P05696	P	Protein kinase C alpha type	PRKCA|PKCA|PRKACA	protein	taxon:9606	20180508	ARUK-UCL	occurs_in(CL:0000540),has_input(UniProtKB:Q7KZI7),negatively_regulates(GO:0018105)	UniProtKB:P17252
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P17947	SPI1	involved_in	GO:0032088	PMID:28362429	IDA		P	Transcription factor PU.1	SPI1	protein	taxon:9606	20201217	ARUK-UCL	happens_during(GO:0002357),has_input(UniProtKB:Q04206)	UniProtKB:P17947
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P17947	SPI1	involved_in	GO:0051090	GO_REF:0000024	ISS	UniProtKB:P17433	P	Transcription factor PU.1	SPI1	protein	taxon:9606	20201202	ARUK-UCL		UniProtKB:P17947
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P18031	PTPN1	acts_upstream_of	GO:0043507	GO_REF:0000024	ISS	UniProtKB:P35821	P	Tyrosine-protein phosphatase non-receptor type 1	PTPN1|PTP1B	protein	taxon:9606	20210421	ARUK-UCL	part_of(GO:0034976)	UniProtKB:P18031
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P20309	CHRM3	acts_upstream_of_or_within	GO:0032412	PMID:17478539	IDA		P	Muscarinic acetylcholine receptor M3	CHRM3	protein	taxon:9606	20200115	ARUK-UCL	occurs_in(CL:0011108),occurs_in(UBERON:0013485),part_of(GO:1905144),has_input(UniProtKB:P55011),occurs_in(GO:0009925)	UniProtKB:P20309
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P20309	CHRM3	acts_upstream_of_or_within	GO:0032412	PMID:17478539	IDA		P	Muscarinic acetylcholine receptor M3	CHRM3	protein	taxon:9606	20200115	ARUK-UCL	occurs_in(CL:0011108),occurs_in(UBERON:0013485),part_of(GO:1905144),has_input(UniProtKB:P55011),occurs_in(GO:0016328)	UniProtKB:P20309
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P20827	EFNA1	involved_in	GO:0001934	PMID:24217950	IGI	UniProtKB:P07948	P	Ephrin-A1	EFNA1|EPLG1|LERK1|TNFAIP4	protein	taxon:9606	20170621	ARUK-UCL	has_input(UniProtKB:P54764)	UniProtKB:P20827
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P20827	EFNA1	involved_in	GO:0001934	PMID:24217950	IGI	UniProtKB:P54764	P	Ephrin-A1	EFNA1|EPLG1|LERK1|TNFAIP4	protein	taxon:9606	20170621	ARUK-UCL	has_input(UniProtKB:P54764),positively_regulates(GO:0018108)	UniProtKB:P20827
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P20827	EFNA1	involved_in	GO:0061098	PMID:24217950	IGI	UniProtKB:P54764	P	Ephrin-A1	EFNA1|EPLG1|LERK1|TNFAIP4	protein	taxon:9606	20170621	ARUK-UCL	has_input(UniProtKB:P07948)	UniProtKB:P20827
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P20827	EFNA1	involved_in	GO:1902961	PMID:24217950	IGI	UniProtKB:P54764	P	Ephrin-A1	EFNA1|EPLG1|LERK1|TNFAIP4	protein	taxon:9606	20170620	ARUK-UCL		UniProtKB:P20827
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P22004	BMP6	involved_in	GO:0050731	PMID:26598555	IDA		P	Bone morphogenetic protein 6	BMP6|VGR	protein	taxon:9606	20190517	ARUK-UCL	has_input(UniProtKB:P33151),occurs_in(CL:2000052)|has_input(UniProtKB:P12931),occurs_in(CL:2000052)	UniProtKB:P22004
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P27448	MARK3	involved_in	GO:0018105	PMID:9543386	IDA		P	MAP/microtubule affinity-regulating kinase 3	MARK3|CTAK1|EMK2	protein	taxon:9606	20180328	ARUK-UCL	has_input(UniProtKB:P30307),positively_regulates(GO:0005515)	UniProtKB:P27448
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P27448	MARK3	involved_in	GO:0036289	PMID:9543386	IDA		P	MAP/microtubule affinity-regulating kinase 3	MARK3|CTAK1|EMK2	protein	taxon:9606	20180328	ARUK-UCL	has_input(UniProtKB:P27448)	UniProtKB:P27448
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P28482	MAPK1	involved_in	GO:0006468	PMID:11404397	TAS		P	Mitogen-activated protein kinase 1	MAPK1|ERK2|PRKM1|PRKM2	protein	taxon:9606	20170210	ARUK-UCL	has_input(UniProtKB:P51812)	UniProtKB:P28482
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P29323	EPHB2	acts_upstream_of	GO:0006469	GO_REF:0000024	ISS	UniProtKB:P54763	P	Ephrin type-B receptor 2	EPHB2|DRT|EPHT3|EPTH3|ERK|HEK5|TYRO5	protein	taxon:9606	20210421	ARUK-UCL		UniProtKB:P29323
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P29323	EPHB2	involved_in	GO:0001933	GO_REF:0000024	ISS	UniProtKB:P54763	P	Ephrin type-B receptor 2	EPHB2|DRT|EPHT3|EPTH3|ERK|HEK5|TYRO5	protein	taxon:9606	20170620	ARUK-UCL	negatively_regulates(GO:0004708)|negatively_regulates(GO:0070371)	UniProtKB:P29323
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P29323	EPHB2	involved_in	GO:0018108	GO_REF:0000024	ISS	UniProtKB:P54763	P	Ephrin type-B receptor 2	EPHB2|DRT|EPHT3|EPTH3|ERK|HEK5|TYRO5	protein	taxon:9606	20170620	ARUK-UCL	has_input(UniProtKB:Q05586)	UniProtKB:P29323
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P29323	EPHB2	involved_in	GO:1904782	GO_REF:0000024	ISS	UniProtKB:P54763	P	Ephrin type-B receptor 2	EPHB2|DRT|EPHT3|EPTH3|ERK|HEK5|TYRO5	protein	taxon:9606	20170620	ARUK-UCL	causally_upstream_of(GO:1900272),occurs_in(CL:2000089)	UniProtKB:P29323
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P29323	EPHB2	involved_in	GO:1904783	GO_REF:0000024	ISS	UniProtKB:P54763	P	Ephrin type-B receptor 2	EPHB2|DRT|EPHT3|EPTH3|ERK|HEK5|TYRO5	protein	taxon:9606	20170620	ARUK-UCL	causally_upstream_of(GO:1900273),occurs_in(CL:2000089)	UniProtKB:P29323
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P30990	NTS	acts_upstream_of	GO:0051092	PMID:21806946	IDA		P	Neurotensin/neuromedin N	NTS	protein	taxon:9606	20210720	ARUK-UCL	causally_upstream_of(GO:0010628)	UniProtKB:P30990
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P31641	SLC6A6	acts_upstream_of	GO:0071705	PMID:24842606	IDA		P	Sodium- and chloride-dependent taurine transporter	SLC6A6	protein	taxon:9606	20200603	ARUK-UCL	has_input(CHEBI:15430)	UniProtKB:P31641
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P31749	AKT1	involved_in	GO:0071901	PMID:28386764	TAS		P	RAC-alpha serine/threonine-protein kinase	AKT1|PKB|RAC	protein	taxon:9606	20180122	ARUK-UCL	has_input(UniProtKB:P49841)	UniProtKB:P31749
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P31994	FCGR2B	involved_in	GO:0010469	PMID:26683154	TAS		P	Low affinity immunoglobulin gamma Fc region receptor II-b	FCGR2B|CD32|FCG2|IGFR2	protein	taxon:9606	20170614	ARUK-UCL		UniProtKB:P31994
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P32418	SLC8A1	acts_upstream_of_or_within	GO:0071901	GO_REF:0000024	ISS	UniProtKB:P70414	P	Sodium/calcium exchanger 1	SLC8A1|CNC|NCX1	protein	taxon:9606	20191210	ARUK-UCL	occurs_in(UBERON:0002421),has_input(UniProtKB:Q9UQM7)	UniProtKB:P32418
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P33151	CDH5	involved_in	GO:0001932	PMID:23159740	IDA		P	Cadherin-5	CDH5	protein	taxon:9606	20190522	ARUK-UCL	has_input(UniProtKB:P12931)|has_input(UniProtKB:Q9UPY8)	UniProtKB:P33151
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P36544	CHRNA7	involved_in	GO:0001934	GO_REF:0000024	ISS	UniProtKB:P49582	P	Neuronal acetylcholine receptor subunit alpha-7	CHRNA7|NACHRA7	protein	taxon:9606	20170120	ARUK-UCL	occurs_in(UBERON:0003027)	UniProtKB:P36544
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P36544	CHRNA7	involved_in	GO:1905920	GO_REF:0000024	ISS	UniProtKB:P49582	P	Neuronal acetylcholine receptor subunit alpha-7	CHRNA7|NACHRA7	protein	taxon:9606	20170213	ARUK-UCL	happens_during(UBERON:0018241),occurs_in(UBERON:0002421),has_input(UniProtKB:Q03059)|happens_during(UBERON:0018241),occurs_in(UBERON:0002743),has_input(UniProtKB:Q03059)	UniProtKB:P36544
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P37840	SNCA	involved_in	GO:0006469	PMID:30194957	TAS		P	Alpha-synuclein	SNCA|NACP|PARK1	protein	taxon:9606	20191218	ARUK-UCL		UniProtKB:P37840
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P37840	SNCA	involved_in	GO:0022898	PMID:18331289	IGI	UniProtKB:P60709	P	Alpha-synuclein	SNCA|NACP|PARK1	protein	taxon:9606	20180515	ARUK-UCL	has_input(UniProtKB:P23975),regulates_transport_of(CHEBI:33569)	UniProtKB:P37840
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P41134	ID1	involved_in	GO:0043433	PMID:7665172	IDA		P	DNA-binding protein inhibitor ID-1	ID1|BHLHB24|ID	protein	taxon:9606	20201127	ARUK-UCL		UniProtKB:P41134
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P41159	LEP	involved_in	GO:0001934	PMID:27037668	IDA		P	Leptin	LEP|OB|OBS	protein	taxon:9606	20191106	ARUK-UCL	occurs_in(CL:2000044),has_input(UniProtKB:P40763)	UniProtKB:P41159
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P41217	CD200	involved_in	GO:0032088	PMID:26670206	IDA		P	OX-2 membrane glycoprotein	CD200|MOX1|MOX2|My033	protein	taxon:9606	20180718	ARUK-UCL	occurs_in(CL:0000235),part_of(GO:0071222),part_of(GO:0071346)	UniProtKB:P41217
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P41217	CD200	involved_in	GO:0032793	PMID:26670206	IDA		P	OX-2 membrane glycoprotein	CD200|MOX1|MOX2|My033	protein	taxon:9606	20180718	ARUK-UCL	occurs_in(CL:0000235),part_of(GO:0071222),part_of(GO:0071346)	UniProtKB:P41217
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P41217	CD200	involved_in	GO:0150072	PMID:26670206	IGI	UniProtKB:P21272	P	OX-2 membrane glycoprotein	CD200|MOX1|MOX2|My033	protein	taxon:9606	20180730	ARUK-UCL	has_input(UniProtKB:P05089),occurs_in(CL:0000235)	UniProtKB:P41217
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P41217	CD200	involved_in	GO:0150074	PMID:26670206	IGI	UniProtKB:P21272	P	OX-2 membrane glycoprotein	CD200|MOX1|MOX2|My033	protein	taxon:9606	20180730	ARUK-UCL	has_input(UniProtKB:P21980),occurs_in(CL:0000235)	UniProtKB:P41217
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P41597	CCR2	involved_in	GO:1904783	GO_REF:0000024	ISS	UniProtKB:O55193	P	C-C chemokine receptor type 2	CCR2|CMKBR2	protein	taxon:9606	20190318	ARUK-UCL	occurs_in(CL:0000540),occurs_in(UBERON:0002181)	UniProtKB:P41597
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P43405	SYK	involved_in	GO:0018108	PMID:11606584	IDA		P	Tyrosine-protein kinase SYK	SYK	protein	taxon:9606	20210216	ARUK-UCL	has_input(UniProtKB:P16885),part_of(GO:0035556)	UniProtKB:P43405
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P43405	SYK	involved_in	GO:0018108	PMID:11606584	IDA		P	Tyrosine-protein kinase SYK	SYK	protein	taxon:9606	20210216	ARUK-UCL	has_input(UniProtKB:P19174),part_of(GO:0035556)	UniProtKB:P43405
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P43405	SYK	involved_in	GO:0018108	PMID:11606584	IMP		P	Tyrosine-protein kinase SYK	SYK	protein	taxon:9606	20210216	ARUK-UCL	has_input(UniProtKB:Q8WV28),part_of(GO:0035556)	UniProtKB:P43405
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P43405	SYK	involved_in	GO:0018108	PMID:14656219	IGI	UniProtKB:P16885	P	Tyrosine-protein kinase SYK	SYK	protein	taxon:9606	20210308	ARUK-UCL	occurs_in(CL:0000233),has_input(UniProtKB:P16885),part_of(GO:0035556)	UniProtKB:P43405
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P43405	SYK	involved_in	GO:0018108	PMID:15509800	IMP		P	Tyrosine-protein kinase SYK	SYK	protein	taxon:9606	20210224	ARUK-UCL	has_input(UniProtKB:P16885),part_of(GO:0050853)	UniProtKB:P43405
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P46109	CRKL	involved_in	GO:0001933	PMID:23959425	IMP		P	Crk-like protein	CRKL	protein	taxon:9606	20180517	ARUK-UCL	occurs_in(CL:0000125),has_input(UniProtKB:Q15796)	UniProtKB:P46109
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P46109	CRKL	involved_in	GO:0001934	PMID:23959425	IMP		P	Crk-like protein	CRKL	protein	taxon:9606	20180517	ARUK-UCL	has_input(UniProtKB:P27361),occurs_in(CL:0000125)|has_input(UniProtKB:P28482),occurs_in(CL:0000125)	UniProtKB:P46109
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P47901	AVPR1B	involved_in	GO:0032430	PMID:9322919	IDA		P	Vasopressin V1b receptor	AVPR1B|AVPR3|VPR3	protein	taxon:9606	20191024	ARUK-UCL		UniProtKB:P47901
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P48029	SLC6A8	acts_upstream_of	GO:0071705	PMID:24842606	IDA		P	Sodium- and chloride-dependent creatine transporter 1	SLC6A8	protein	taxon:9606	20200603	ARUK-UCL	has_input(CHEBI:15430)	UniProtKB:P48029
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P48067	SLC6A9	acts_upstream_of	GO:1904782	GO_REF:0000024	ISS	UniProtKB:P28571	P	Sodium- and chloride-dependent glycine transporter 1	SLC6A9	protein	taxon:9606	20200612	ARUK-UCL	occurs_in(CL:1001571)	UniProtKB:P48067
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P48357	LEPR	involved_in	GO:0001934	PMID:27037668	IDA		P	Leptin receptor	LEPR|DB|OBR	protein	taxon:9606	20191104	ARUK-UCL	occurs_in(CL:2000044),has_input(UniProtKB:P40763)	UniProtKB:P48357
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P49840	GSK3A	involved_in	GO:0018107	PMID:25897075	IDA		P	Glycogen synthase kinase-3 alpha	GSK3A	protein	taxon:9606	20171120	ARUK-UCL	has_input(UniProtKB:Q6R327)	UniProtKB:P49840
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P49841	GSK3B	involved_in	GO:0018105	PMID:17139249	IDA		P	Glycogen synthase kinase-3 beta	GSK3B	protein	taxon:9606	20171109	ARUK-UCL	has_input(UniProtKB:Q96G01),regulates(GO:0000226),regulates(GO:0045505)	UniProtKB:P49841
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P49841	GSK3B	involved_in	GO:0018107	PMID:17139249	IDA		P	Glycogen synthase kinase-3 beta	GSK3B	protein	taxon:9606	20171017	ARUK-UCL	has_input(UniProtKB:Q96G01),regulates(GO:0000226),regulates(GO:0045505)	UniProtKB:P49841
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P49841	GSK3B	involved_in	GO:0018107	PMID:25897075	IDA		P	Glycogen synthase kinase-3 beta	GSK3B	protein	taxon:9606	20171120	ARUK-UCL	has_input(UniProtKB:Q6R327)	UniProtKB:P49841
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P49841	GSK3B	involved_in	GO:1901984	GO_REF:0000024	ISS	UniProtKB:P18266	P	Glycogen synthase kinase-3 beta	GSK3B	protein	taxon:9606	20180313	ARUK-UCL	occurs_in(CL:0002608),occurs_in(GO:0015630)	UniProtKB:P49841
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P51812	RPS6KA3	involved_in	GO:0018105	PMID:11404397	TAS		P	Ribosomal protein S6 kinase alpha-3	RPS6KA3|ISPK1|MAPKAPK1B|RSK2	protein	taxon:9606	20170210	ARUK-UCL	has_input(UniProtKB:P16220)	UniProtKB:P51812
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P52797	EFNA3	involved_in	GO:1902961	PMID:24217950	IGI	UniProtKB:P54764	P	Ephrin-A3	EFNA3|EFL2|EPLG3|LERK3	protein	taxon:9606	20170620	ARUK-UCL		UniProtKB:P52797
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P53041	PPP5C	involved_in	GO:0035970	PMID:16262633	TAS		P	Serine/threonine-protein phosphatase 5	PPP5C|PPP5	protein	taxon:9606	20171207	ARUK-UCL		UniProtKB:P53041
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P53041	PPP5C	involved_in	GO:0070262	PMID:16262633	TAS		P	Serine/threonine-protein phosphatase 5	PPP5C|PPP5	protein	taxon:9606	20171207	ARUK-UCL		UniProtKB:P53041
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P53794	SLC5A3	acts_upstream_of_or_within	GO:0043085	GO_REF:0000024	ISS	UniProtKB:Q80WA5	P	Sodium/myo-inositol cotransporter	SLC5A3	protein	taxon:9606	20200329	ARUK-UCL	has_input(UniProtKB:P04839)	UniProtKB:P53794
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P54646	PRKAA2	involved_in	GO:2000758	GO_REF:0000024	ISS	UniProtKB:Q8BRK8	P	5'-AMP-activated protein kinase catalytic subunit alpha-2	PRKAA2|AMPK|AMPK2	protein	taxon:9606	20180309	ARUK-UCL	part_of(GO:0034599),has_input(UniProtKB:Q71U36)	UniProtKB:P54646
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P54710	FXYD2	involved_in	GO:1903408	GO_REF:0000024	ISS	UniProtKB:Q58K79	P	Sodium/potassium-transporting ATPase subunit gamma	FXYD2|ATP1C|ATP1G1	protein	taxon:9606	20201111	ARUK-UCL	has_input(UniProtKB:P05023)	UniProtKB:P54710
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P54764	EPHA4	involved_in	GO:0061098	GO_REF:0000024	ISS	UniProtKB:Q03137	P	Ephrin type-A receptor 4	EPHA4|HEK8|SEK|TYRO1	protein	taxon:9606	20170627	ARUK-UCL	occurs_in(CL:0002608),has_input(UniProtKB:P00519)	UniProtKB:P54764
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P54764	EPHA4	involved_in	GO:1902961	PMID:24217950	IGI	UniProtKB:P20827|UniProtKB:P52797	P	Ephrin type-A receptor 4	EPHA4|HEK8|SEK|TYRO1	protein	taxon:9606	20170620	ARUK-UCL		UniProtKB:P54764
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P57103	SLC8A3	acts_upstream_of_or_within	GO:0071901	GO_REF:0000024	ISS	UniProtKB:S4R2P9	P	Sodium/calcium exchanger 3	SLC8A3|NCX3	protein	taxon:9606	20191210	ARUK-UCL	occurs_in(UBERON:0002421),has_input(UniProtKB:Q9UQM7)	UniProtKB:P57103
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P60709	ACTB	involved_in	GO:0000079	GO_REF:0000024	ISS	UniProtKB:P60711	P	Actin, cytoplasmic 1	ACTB	protein	taxon:9606	20180514	ARUK-UCL	has_input(UniProtKB:Q00535),happens_during(GO:0030036)	UniProtKB:P60709
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P60709	ACTB	involved_in	GO:0022898	PMID:18331289	IGI	UniProtKB:P37840	P	Actin, cytoplasmic 1	ACTB	protein	taxon:9606	20180515	ARUK-UCL	has_input(UniProtKB:P23975),regulates_transport_of(CHEBI:33569)	UniProtKB:P60709
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P60709	ACTB	involved_in	GO:0022898	PMID:18331289	ISS	UniProtKB:P60711	P	Actin, cytoplasmic 1	ACTB	protein	taxon:9606	20180515	ARUK-UCL	has_input(UniProtKB:P23975),regulates_transport_of(CHEBI:33569),occurs_in(CL:0000540),occurs_in(UBERON:0001870)	UniProtKB:P60709
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P60709	ACTB	involved_in	GO:0022898	PMID:18331289	ISS	UniProtKB:P60711	P	Actin, cytoplasmic 1	ACTB	protein	taxon:9606	20180515	ARUK-UCL	has_input(UniProtKB:P23975),regulates_transport_of(CHEBI:33569),occurs_in(CL:0000540),occurs_in(UBERON:0002148)	UniProtKB:P60709
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P62714	PPP2CB	involved_in	GO:0032088	PMID:28159925	IGI	UniProtKB:Q04206	P	Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	PPP2CB	protein	taxon:9606	20210716	ARUK-UCL	occurs_in(CL:0000134)	UniProtKB:P62714
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P62714	PPP2CB	involved_in	GO:0035970	PMID:16262633	TAS		P	Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	PPP2CB	protein	taxon:9606	20171207	ARUK-UCL		UniProtKB:P62714
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P62714	PPP2CB	involved_in	GO:0070262	PMID:16262633	TAS		P	Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	PPP2CB	protein	taxon:9606	20171207	ARUK-UCL		UniProtKB:P62714
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P67775	PPP2CA	involved_in	GO:0001932	PMID:28386764	NAS		P	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	PPP2CA	protein	taxon:9606	20180122	ARUK-UCL	has_input(UniProtKB:P10636)	UniProtKB:P67775
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P67775	PPP2CA	involved_in	GO:0035970	PMID:16262633	TAS		P	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	PPP2CA	protein	taxon:9606	20171207	ARUK-UCL		UniProtKB:P67775
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P67775	PPP2CA	involved_in	GO:0070262	PMID:16262633	TAS		P	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	PPP2CA	protein	taxon:9606	20171207	ARUK-UCL		UniProtKB:P67775
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q00535	CDK5	involved_in	GO:0006468	PMID:17491008	TAS		P	Cyclin-dependent kinase 5	CDK5|CDKN5|PSSALRE	protein	taxon:9606	20171030	ARUK-UCL	has_input(UniProtKB:P46821)|has_input(UniProtKB:P11137)|has_input(UniProtKB:P10636)|has_input(UniProtKB:O43602)	UniProtKB:Q00535
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q00535	CDK5	involved_in	GO:0018105	GO_REF:0000024	ISS	UniProtKB:P49615	P	Cyclin-dependent kinase 5	CDK5|CDKN5|PSSALRE	protein	taxon:9606	20171030	ARUK-UCL	has_input(UniProtKB:Q13224),occurs_in(UBERON:0002421),regulates(GO:0072659)	UniProtKB:Q00535
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q00535	CDK5	involved_in	GO:0018107	GO_REF:0000024	ISS	UniProtKB:P49615	P	Cyclin-dependent kinase 5	CDK5|CDKN5|PSSALRE	protein	taxon:9606	20171030	ARUK-UCL	has_input(UniProtKB:Q9UD71),occurs_in(UBERON:0002421)	UniProtKB:Q00535
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q00613	HSF1	involved_in	GO:0051091	PMID:24504023	IMP		P	Heat shock factor protein 1	HSF1|HSTF1	protein	taxon:9606	20201211	ARUK-UCL	has_input(UniProtKB:P17947),happens_during(GO:0030225)	UniProtKB:Q00613
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q02763	TEK	involved_in	GO:0001934	PMID:15985432	IMP		P	Angiopoietin-1 receptor	TEK|TIE2|VMCM|VMCM1	protein	taxon:9606	20190603	ARUK-UCL	occurs_in(CL:0002618),has_input(UniProtKB:P27361)|occurs_in(CL:0002618),has_input(UniProtKB:P28482)|occurs_in(CL:0002618),has_input(UniProtKB:P29474)	UniProtKB:Q02763
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q04771	ACVR1	involved_in	GO:0050731	PMID:26598555	IMP		P	Activin receptor type-1	ACVR1|ACVRLK2	protein	taxon:9606	20190517	ARUK-UCL	has_input(UniProtKB:P33151),occurs_in(CL:0002618)	UniProtKB:Q04771
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q06124	PTPN11	involved_in	GO:0050731	PMID:26706435	IMP		P	Tyrosine-protein phosphatase non-receptor type 11	PTPN11|PTP2C|SHPTP2	protein	taxon:9606	20211119	ARUK-UCL	has_input(UniProtKB:Q13480),occurs_in(CL:0002618)	UniProtKB:Q06124
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q06187	BTK	involved_in	GO:0018108	PMID:11606584	IDA		P	Tyrosine-protein kinase BTK	BTK|AGMX1|ATK|BPK	protein	taxon:9606	20210216	ARUK-UCL	has_input(UniProtKB:P16885),part_of(GO:0035556)	UniProtKB:Q06187
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q06187	BTK	involved_in	GO:0018108	PMID:14656219	IGI	UniProtKB:P16885	P	Tyrosine-protein kinase BTK	BTK|AGMX1|ATK|BPK	protein	taxon:9606	20210308	ARUK-UCL	occurs_in(CL:0000233),has_input(UniProtKB:P16885),part_of(GO:0035556)	UniProtKB:Q06187
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q06187	BTK	involved_in	GO:0018108	PMID:15509800	IDA		P	Tyrosine-protein kinase BTK	BTK|AGMX1|ATK|BPK	protein	taxon:9606	20210224	ARUK-UCL	has_input(UniProtKB:P16885),part_of(GO:0050853)	UniProtKB:Q06187
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q07954	LRP1	acts_upstream_of	GO:1905049	PMID:26781079	IC	GO:0006898	P	Prolow-density lipoprotein receptor-related protein 1	LRP1|A2MR|APR	protein	taxon:9606	20190624	ARUK-UCL	has_input(UniProtKB:P14780),occurs_in(CL:0000359)	UniProtKB:Q07954
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q09472	EP300	involved_in	GO:0018394	PMID:23962722	IDA		P	Histone acetyltransferase p300	EP300|P300	protein	taxon:9606	20180125	ARUK-UCL	has_input(UniProtKB:P10636-6),negatively_regulates(GO:0051259)	UniProtKB:Q09472
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q12852	MAP3K12	involved_in	GO:0018105	GO_REF:0000024	ISS	UniProtKB:Q60700	P	Mitogen-activated protein kinase kinase kinase 12	MAP3K12|ZPK	protein	taxon:9606	20180716	ARUK-UCL	has_input(UniProtKB:P45985),occurs_in(CL:0000540)	UniProtKB:Q12852
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q12852	MAP3K12	involved_in	GO:0043507	GO_REF:0000024	ISS	UniProtKB:Q60700	P	Mitogen-activated protein kinase kinase kinase 12	MAP3K12|ZPK	protein	taxon:9606	20210421	ARUK-UCL	has_input(UniProtKB:P45984),occurs_in(CL:0000540)|has_input(UniProtKB:P45983),occurs_in(CL:0000540)	UniProtKB:Q12852
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q12852	MAP3K12	involved_in	GO:0045860	GO_REF:0000024	ISS	UniProtKB:Q60700	P	Mitogen-activated protein kinase kinase kinase 12	MAP3K12|ZPK	protein	taxon:9606	20210421	ARUK-UCL	has_input(UniProtKB:P45985),occurs_in(CL:0000540)	UniProtKB:Q12852
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q12913	PTPRJ	involved_in	GO:0050731	GO_REF:0000024	ISS	UniProtKB:Q64455	P	Receptor-type tyrosine-protein phosphatase eta	PTPRJ|DEP1	protein	taxon:9606	20180725	ARUK-UCL	has_input(UniProtKB:P07948)	UniProtKB:Q12913
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q13131	PRKAA1	involved_in	GO:2000758	GO_REF:0000024	ISS	UniProtKB:Q5EG47	P	5'-AMP-activated protein kinase catalytic subunit alpha-1	PRKAA1|AMPK1	protein	taxon:9606	20180309	ARUK-UCL	part_of(GO:0034599),has_input(UniProtKB:Q71U36)	UniProtKB:Q13131
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q13464	ROCK1	involved_in	GO:0010922	PMID:27221467	IMP		P	Rho-associated protein kinase 1	ROCK1	protein	taxon:9606	20210720	ARUK-UCL	has_input(UniProtKB:P60484),occurs_in(CL:0002319)	UniProtKB:Q13464
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q13526	PIN1	involved_in	GO:0001932	PMID:24964035	IDA		P	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	PIN1	protein	taxon:9606	20180516	ARUK-UCL	has_input(UniProtKB:Q15796)	UniProtKB:Q13526
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q13627	DYRK1A	involved_in	GO:0006468	PMID:24327345	TAS		P	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	DYRK1A|DYRK|MNB|MNBH	protein	taxon:9606	20171204	ARUK-UCL	has_input(UniProtKB:O43426)|has_input(UniProtKB:P49418)|has_input(UniProtKB:P10636)|has_input(UniProtKB:P46821)|has_input(UniProtKB:P37840)	UniProtKB:Q13627
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q13627	DYRK1A	involved_in	GO:0006468	PMID:28377597	TAS		P	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	DYRK1A|DYRK|MNB|MNBH	protein	taxon:9606	20171204	ARUK-UCL	has_input(UniProtKB:O75533)|has_input(UniProtKB:Q96S94)|has_input(UniProtKB:Q07955)|has_input(UniProtKB:Q16629)|has_input(UniProtKB:Q01130)|has_input(UniProtKB:Q13247)	UniProtKB:Q13627
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q13627	DYRK1A	involved_in	GO:0018105	GO_REF:0000024	ISS	UniProtKB:Q63470	P	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	DYRK1A|DYRK|MNB|MNBH	protein	taxon:9606	20171205	ARUK-UCL	has_input(UniProtKB:Q16629)	UniProtKB:Q13627
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q13627	DYRK1A	involved_in	GO:0018105	PMID:25556849	IGI	UniProtKB:Q9Y463	P	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	DYRK1A|DYRK|MNB|MNBH	protein	taxon:9606	20180130	ARUK-UCL	has_input(UniProtKB:P10636-8),occurs_in(CL:0000540)	UniProtKB:Q13627
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q13627	DYRK1A	involved_in	GO:0018107	PMID:25556849	ISS	UniProtKB:Q63470	P	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	DYRK1A|DYRK|MNB|MNBH	protein	taxon:9606	20180130	ARUK-UCL	has_input(UniProtKB:P10636-8),occurs_in(CL:0010012)	UniProtKB:Q13627
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q13627	DYRK1A	involved_in	GO:0036289	PMID:24327345	TAS		P	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	DYRK1A|DYRK|MNB|MNBH	protein	taxon:9606	20171204	ARUK-UCL	causally_upstream_of(GO:0033674)	UniProtKB:Q13627
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q13627	DYRK1A	involved_in	GO:0038083	PMID:24327345	IDA		P	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	DYRK1A|DYRK|MNB|MNBH	protein	taxon:9606	20171205	ARUK-UCL	occurs_in(GO:0005829)	UniProtKB:Q13627
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q13627	DYRK1A	involved_in	GO:0038083	PMID:24327345	TAS		P	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	DYRK1A|DYRK|MNB|MNBH	protein	taxon:9606	20171204	ARUK-UCL	positively_regulates(GO:0016301)	UniProtKB:Q13627
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q14469	HES1	involved_in	GO:0043433	GO_REF:0000024	ISS	UniProtKB:P35428	P	Transcription factor HES-1	HES1|BHLHB39|HL|HRY	protein	taxon:9606	20200505	ARUK-UCL		UniProtKB:Q14469
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q15078	CDK5R1	involved_in	GO:2000273	PMID:29020624	IDA		P	Cyclin-dependent kinase 5 activator 1	CDK5R1|CDK5R|NCK5A	protein	taxon:9606	20201016	ARUK-UCL	occurs_in(CL:0000129),has_input(UniProtKB:P25942)	UniProtKB:Q15078-PRO_0000004795
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q15078	CDK5R1	involved_in	GO:2000273	PMID:29020624	IDA		P	Cyclin-dependent kinase 5 activator 1	CDK5R1|CDK5R|NCK5A	protein	taxon:9606	20201016	ARUK-UCL	occurs_in(CL:0000129),has_input(UniProtKB:Q07108)	UniProtKB:Q15078-PRO_0000004795
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q15109	AGER	involved_in	GO:0001934	PMID:15457210	IGI	UniProtKB:P05067	P	Advanced glycosylation end product-specific receptor	AGER|RAGE	protein	taxon:9606	20170928	ARUK-UCL	happens_during(UBERON:0007222),positively_regulates(GO:0004683),occurs_in(UBERON:0002421)	UniProtKB:Q15109
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q15109	AGER	involved_in	GO:0001934	PMID:15457210	IGI	UniProtKB:P05067	P	Advanced glycosylation end product-specific receptor	AGER|RAGE	protein	taxon:9606	20170928	ARUK-UCL	has_input(UniProtKB:Q16539),happens_during(UBERON:0018241)	UniProtKB:Q15109
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q15109	AGER	involved_in	GO:0001934	PMID:15457210	IGI	UniProtKB:P05067	P	Advanced glycosylation end product-specific receptor	AGER|RAGE	protein	taxon:9606	20170928	ARUK-UCL	part_of(GO:0032793),happens_during(UBERON:0018241)	UniProtKB:Q15109
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q15109	AGER	involved_in	GO:1902961	PMID:22406537	IGI	UniProtKB:P05067-PRO_0000000093	P	Advanced glycosylation end product-specific receptor	AGER|RAGE	protein	taxon:9606	20190717	ARUK-UCL	occurs_in(UBERON:0000956),has_input(UniProtKB:P56817)|occurs_in(UBERON:0002421),has_input(UniProtKB:P56817)	UniProtKB:Q15109
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q15139	PRKD1	acts_upstream_of	GO:0018107	GO_REF:0000024	ISS	UniProtKB:Q62101	P	Serine/threonine-protein kinase D1	PRKD1|PKD|PKD1|PRKCM	protein	taxon:9606	20200119	ARUK-UCL	has_input(UniProtKB:Q9UHW9)	UniProtKB:Q15139
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q15389	ANGPT1	involved_in	GO:0001934	PMID:19148554	IMP		P	Angiopoietin-1	ANGPT1|KIAA0003	protein	taxon:9606	20190926	ARUK-UCL	occurs_in(CL:2000008)	UniProtKB:Q15389
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q15555	MAPRE2	involved_in	GO:0043547	PMID:25490267	ISS	UniProtKB:Q8R001	P	Microtubule-associated protein RP/EB family member 2	MAPRE2|RP1	protein	taxon:9606	20180719	ARUK-UCL	occurs_in(CL:0000312),has_input(UniProtKB:P62330)	UniProtKB:Q15555
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q15569	TESK1	involved_in	GO:0031953	PMID:18216281	ISS	UniProtKB:Q63572	P	Dual specificity testis-specific protein kinase 1	TESK1	protein	taxon:9606	20171109	ARUK-UCL	has_input(UniProtKB:Q7L7X3)	UniProtKB:Q15569
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q15569	TESK1	involved_in	GO:0071901	PMID:18216281	ISS	UniProtKB:Q63572	P	Dual specificity testis-specific protein kinase 1	TESK1	protein	taxon:9606	20171109	ARUK-UCL	has_input(UniProtKB:Q7L7X3)	UniProtKB:Q15569
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q15848	ADIPOQ	involved_in	GO:0110113	PMID:18703020	IDA		P	Adiponectin	ADIPOQ|ACDC|ACRP30|APM1|GBP28	protein	taxon:9606	20201016	ARUK-UCL	occurs_in(CL:0000235),has_output(UniProtKB:O95477)	UniProtKB:Q15848
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q16625	OCLN	involved_in	GO:0001933	PMID:28718701	IMP		P	Occludin	OCLN	protein	taxon:9606	20191003	ARUK-UCL	occurs_in(CL:0000669),has_input(UniProtKB:P08047)	UniProtKB:Q16625
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q4V9L6	TMEM119	involved_in	GO:0001934	GO_REF:0000024	ISS	UniProtKB:Q8R138	P	Transmembrane protein 119	TMEM119|PSEC0199|UNQ731/PRO1415	protein	taxon:9606	20190315	ARUK-UCL		UniProtKB:Q4V9L6
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q5T9C9	PIP5KL1	involved_in	GO:0001933	PMID:19680787	IMP		P	Phosphatidylinositol 4-phosphate 5-kinase-like protein 1	PIP5KL1	protein	taxon:9606	20180627	ARUK-UCL		UniProtKB:Q5T9C9
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q5TCY1	TTBK1	involved_in	GO:0018105	PMID:16923168	IDA		P	Tau-tubulin kinase 1	TTBK1|BDTK|KIAA1855	protein	taxon:9606	20190619	ARUK-UCL	has_input(UniProtKB:P10636),positively_regulates(GO:0051258)	UniProtKB:Q5TCY1
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q5TCY1	TTBK1	involved_in	GO:0018107	PMID:16923168	IDA		P	Tau-tubulin kinase 1	TTBK1|BDTK|KIAA1855	protein	taxon:9606	20190619	ARUK-UCL	has_input(UniProtKB:P10636),positively_regulates(GO:0051258)	UniProtKB:Q5TCY1
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q5TCY1	TTBK1	involved_in	GO:0018108	PMID:16923168	IDA		P	Tau-tubulin kinase 1	TTBK1|BDTK|KIAA1855	protein	taxon:9606	20190619	ARUK-UCL	has_input(UniProtKB:P10636),positively_regulates(GO:0051258)	UniProtKB:Q5TCY1
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q6EIG7	CLEC6A	acts_upstream_of	GO:0050731	GO_REF:0000024	ISS	UniProtKB:Q9JKF4	P	C-type lectin domain family 6 member A	CLEC6A|CLECSF10|DECTIN2	protein	taxon:9606	20210416	ARUK-UCL	has_input(UniProtKB:P43405),occurs_in(CL:0000235),part_of(GO:1902533)	UniProtKB:Q6EIG7
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q6IQ55	TTBK2	involved_in	GO:0018105	PMID:26323690	IDA		P	Tau-tubulin kinase 2	TTBK2|KIAA0847	protein	taxon:9606	20211119	ARUK-UCL	has_input(UniProtKB:O00139),negatively_regulates(GO:0007019),negatively_regulates(GO:0008017),occurs_in(GO:0005874)	UniProtKB:Q6IQ55
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q6P1M0	SLC27A4	acts_upstream_of_or_within	GO:0090630	PMID:25603556	IDA		P	Long-chain fatty acid transport protein 4	SLC27A4|ACSVL4|FATP4	protein	taxon:9606	20200923	ARUK-UCL	has_input(UniProtKB:P63000)	UniProtKB:Q6P1M0
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q6ZMJ4	IL34	acts_upstream_of_or_within	GO:0043406	PMID:26754294	IDA		P	Interleukin-34	IL34|C16orf77	protein	taxon:9606	20200320	ARUK-UCL	has_input(UniProtKB:P28482),occurs_in(CL:0000235)|has_input(UniProtKB:P27361),occurs_in(CL:0000235)	UniProtKB:Q6ZMJ4
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q6ZMJ4	IL34	acts_upstream_of_or_within	GO:0061098	PMID:26754294	IDA		P	Interleukin-34	IL34|C16orf77	protein	taxon:9606	20200320	ARUK-UCL	has_input(UniProtKB:Q05397),occurs_in(CL:0000235)	UniProtKB:Q6ZMJ4
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q7KZI7	MARK2	involved_in	GO:0018105	PMID:10542369	IDA		P	Serine/threonine-protein kinase MARK2	MARK2|EMK1	protein	taxon:9606	20180328	ARUK-UCL	has_input(UniProtKB:P11137),negatively_regulates(GO:0000226)|has_input(UniProtKB:P27816),negatively_regulates(GO:0000226)	UniProtKB:Q7KZI7
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q7KZI7	MARK2	involved_in	GO:0018105	PMID:16717194	IDA		P	Serine/threonine-protein kinase MARK2	MARK2|EMK1	protein	taxon:9606	20180508	ARUK-UCL	has_input(UniProtKB:P10636)	UniProtKB:Q7KZI7
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q7KZI7	MARK2	involved_in	GO:0018105	PMID:16717194	ISS	UniProtKB:O08679	P	Serine/threonine-protein kinase MARK2	MARK2|EMK1	protein	taxon:9606	20180508	ARUK-UCL	occurs_in(CL:0000540),has_input(UniProtKB:P10636)	UniProtKB:Q7KZI7
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q7KZI7	MARK2	involved_in	GO:0018105	PMID:24251416	ISS	UniProtKB:O08679	P	Serine/threonine-protein kinase MARK2	MARK2|EMK1	protein	taxon:9606	20180515	ARUK-UCL	has_input(UniProtKB:P10636),regulates(GO:0008017)	UniProtKB:Q7KZI7
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q7L7X3	TAOK1	involved_in	GO:0016310	PMID:12639963	IDA		P	Serine/threonine-protein kinase TAO1	TAOK1|KIAA1361|MAP3K16|MARKK	protein	taxon:9606	20190904	ARUK-UCL	has_input(GO:0045298)	UniProtKB:Q7L7X3
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q7L7X3	TAOK1	involved_in	GO:0046777	PMID:18216281	ISS	UniProtKB:O88664	P	Serine/threonine-protein kinase TAO1	TAOK1|KIAA1361|MAP3K16|MARKK	protein	taxon:9606	20171109	ARUK-UCL		UniProtKB:Q7L7X3
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q7L7X3	TAOK1	involved_in	GO:1901985	PMID:12639963	IMP		P	Serine/threonine-protein kinase TAO1	TAOK1|KIAA1361|MAP3K16|MARKK	protein	taxon:9606	20180515	ARUK-UCL	part_of(GO:0000226)	UniProtKB:Q7L7X3
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q7Z699	SPRED1	involved_in	GO:0006469	PMID:18216281	IDA		P	Sprouty-related, EVH1 domain-containing protein 1	SPRED1	protein	taxon:9606	20171109	ARUK-UCL	has_input(UniProtKB:Q15569)	UniProtKB:Q7Z699
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q8IV16	GPIHBP1	involved_in	GO:0051006	PMID:29899144	IDA		P	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1	GPIHBP1|HBP1	protein	taxon:9606	20190715	ARUK-UCL	has_input(UniProtKB:P06858)	UniProtKB:Q8IV16
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q8N2Q7	NLGN1	involved_in	GO:2000310	GO_REF:0000024	ISS	UniProtKB:Q62765	P	Neuroligin-1	NLGN1|KIAA1070	protein	taxon:9606	20170814	ARUK-UCL	occurs_in(UBERON:0002421)	UniProtKB:Q8N2Q7
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q8N6F1	CLDN19	involved_in	GO:0001934	PMID:27593915	IMP		P	Claudin-19	CLDN19	protein	taxon:9606	20190916	ARUK-UCL		UniProtKB:Q8N6F1
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q8NHJ6	LILRB4	involved_in	GO:0061099	PMID:16493035	IMP		P	Leukocyte immunoglobulin-like receptor subfamily B member 4	LILRB4|ILT3|LIR5	protein	taxon:9606	20200930	ARUK-UCL	has_input(UniProtKB:P29350)	UniProtKB:Q8NHJ6
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q8NHJ6	LILRB4	involved_in	GO:0061099	PMID:9151699	IDA		P	Leukocyte immunoglobulin-like receptor subfamily B member 4	LILRB4|ILT3|LIR5	protein	taxon:9606	20200930	ARUK-UCL	has_input(UniProtKB:P29350)	UniProtKB:Q8NHJ6
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q8NHJ6	LILRB4	involved_in	GO:2000272	PMID:9151699	IDA		P	Leukocyte immunoglobulin-like receptor subfamily B member 4	LILRB4|ILT3|LIR5	protein	taxon:9606	20201001	ARUK-UCL	has_input(UniProtKB:P29350)	UniProtKB:Q8NHJ6
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q8TDC3	BRSK1	involved_in	GO:0006468	PMID:27626661	TAS		P	Serine/threonine-protein kinase BRSK1	BRSK1|KIAA1811|SAD1|SADB	protein	taxon:9606	20180516	ARUK-UCL	has_input(UniProtKB:Q86UR5)	UniProtKB:Q8TDC3
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q8WW43	APH1B	involved_in	GO:0010950	PMID:12297508	IMP		P	Gamma-secretase subunit APH-1B	APH1B|PSFL|UNQ688/PRO1328	protein	taxon:9606	20201110	ARUK-UCL	has_input(UniProtKB:P49768)|has_input(UniProtKB:P49810)	UniProtKB:Q8WW43
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q8WW43	APH1B	involved_in	GO:0010950	PMID:12763021	IGI	UniProtKB:P05067|UniProtKB:P49768	P	Gamma-secretase subunit APH-1B	APH1B|PSFL|UNQ688/PRO1328	protein	taxon:9606	20201110	ARUK-UCL		UniProtKB:Q8WW43
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q92542	NCSTN	involved_in	GO:0010950	PMID:12297508	IMP		P	Nicastrin	NCSTN|KIAA0253|UNQ1874/PRO4317	protein	taxon:9606	20201110	ARUK-UCL	has_input(UniProtKB:P49768)|has_input(UniProtKB:P49810)	UniProtKB:Q92542
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q92542	NCSTN	involved_in	GO:0010950	PMID:12763021	IGI	UniProtKB:P05067|UniProtKB:P49768	P	Nicastrin	NCSTN|KIAA0253|UNQ1874/PRO4317	protein	taxon:9606	20201110	ARUK-UCL		UniProtKB:Q92542
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q92793	CREBBP	involved_in	GO:0006473	PMID:28386764	TAS		P	CREB-binding protein	CREBBP|CBP	protein	taxon:9606	20180122	ARUK-UCL	has_input(UniProtKB:P10636)	UniProtKB:Q92793
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q96BI3	APH1A	involved_in	GO:0010950	PMID:12297508	IMP		P	Gamma-secretase subunit APH-1A	APH1A|PSF|CGI-78|UNQ579/PRO1141	protein	taxon:9606	20201110	ARUK-UCL	has_input(UniProtKB:P49768)|has_input(UniProtKB:P49810)	UniProtKB:Q96BI3
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q96BI3	APH1A	involved_in	GO:0010950	PMID:12763021	IGI	UniProtKB:P05067|UniProtKB:P49768	P	Gamma-secretase subunit APH-1A	APH1A|PSF|CGI-78|UNQ579/PRO1141	protein	taxon:9606	20201110	ARUK-UCL		UniProtKB:Q96BI3
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q96HZ4	HES6	involved_in	GO:0043433	GO_REF:0000024	ISS	UniProtKB:Q9JHE6	P	Transcription cofactor HES-6	HES6|BHLHB41	protein	taxon:9606	20200505	ARUK-UCL		UniProtKB:Q96HZ4
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q96SZ6	CDK5RAP1	involved_in	GO:0045736	PMID:17491008	TAS		P	Mitochondrial tRNA methylthiotransferase CDK5RAP1	CDK5RAP1|C20orf34|CGI-05|HSPC167	protein	taxon:9606	20171030	ARUK-UCL	has_input(UniProtKB:Q00535)	UniProtKB:Q96SZ6
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q99962	SH3GL2	involved_in	GO:0001933	PMID:24854121	IMP		P	Endophilin-A1	SH3GL2|CNSA2|SH3D2A	protein	taxon:9606	20190920	ARUK-UCL	occurs_in(CL:2000044),has_input(UniProtKB:P28482)|occurs_in(CL:2000044),has_input(UniProtKB:P27361)	UniProtKB:Q99962
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9BXN2	CLEC7A	acts_upstream_of_or_within	GO:0051091	GO_REF:0000024	ISS	UniProtKB:Q6QLQ4	P	C-type lectin domain family 7 member A	CLEC7A|BGR|CLECSF12|DECTIN1|UNQ539/PRO1082	protein	taxon:9606	20210416	ARUK-UCL	occurs_in(CL:0000451),has_input(UniProtKB:P05412),part_of(GO:0001878)	UniProtKB:Q9BXN2
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9BXN2	CLEC7A	acts_upstream_of_or_within	GO:0051091	GO_REF:0000024	ISS	UniProtKB:Q6QLQ4	P	C-type lectin domain family 7 member A	CLEC7A|BGR|CLECSF12|DECTIN1|UNQ539/PRO1082	protein	taxon:9606	20210416	ARUK-UCL	occurs_in(CL:0000451),has_input(UniProtKB:Q12968),part_of(GO:0001878)	UniProtKB:Q9BXN2
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9BXN2	CLEC7A	acts_upstream_of_or_within	GO:0051091	GO_REF:0000024	ISS	UniProtKB:Q6QLQ4	P	C-type lectin domain family 7 member A	CLEC7A|BGR|CLECSF12|DECTIN1|UNQ539/PRO1082	protein	taxon:9606	20210416	ARUK-UCL	occurs_in(CL:0000451),has_input(UniProtKB:Q13469),part_of(GO:0001878)	UniProtKB:Q9BXN2
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9BXN2	CLEC7A	involved_in	GO:0051092	GO_REF:0000024	ISS	UniProtKB:Q6QLQ4	P	C-type lectin domain family 7 member A	CLEC7A|BGR|CLECSF12|DECTIN1|UNQ539/PRO1082	protein	taxon:9606	20210416	ARUK-UCL	occurs_in(CL:0000451),part_of(GO:0001878)	UniProtKB:Q9BXN2
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9BY76	ANGPTL4	involved_in	GO:0051005	PMID:29899144	IDA		P	Angiopoietin-related protein 4	ANGPTL4|ARP4|HFARP|PGAR|PP1158|PSEC0166|UNQ171/PRO197	protein	taxon:9606	20190715	ARUK-UCL	has_input(UniProtKB:P06858)	UniProtKB:Q9BY76
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9BYF1	ACE2	acts_upstream_of	GO:2000272	PMID:18258853	IMP		P	Angiotensin-converting enzyme 2	ACE2|UNQ868/PRO1885	protein	taxon:9606	20201016	ARUK-UCL	has_input(UniProtKB:P30556)	UniProtKB:Q9BYF1
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9BYF1	ACE2	involved_in	GO:0022898	PMID:25534429	IGI	UniProtKB:Q9NP91	P	Angiotensin-converting enzyme 2	ACE2|UNQ868/PRO1885	protein	taxon:9606	20200610	ARUK-UCL	has_input(UniProtKB:Q9NP91),part_of(GO:1905737)	UniProtKB:Q9BYF1
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9BYP7	WNK3	acts_upstream_of	GO:0018107	PMID:27782176	ISS	UniProtKB:Q80XP9	P	Serine/threonine-protein kinase WNK3	WNK3|KIAA1566|PRKWNK3	protein	taxon:9606	20200119	ARUK-UCL	has_input(UniProtKB:Q9UHW9),causally_upstream_of(GO:1904062)	UniProtKB:Q9BYP7
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9H1K1	ISCU	involved_in	GO:1904234	PMID:20436681	IMP		P	Iron-sulfur cluster assembly enzyme ISCU	ISCU|NIFUN	protein	taxon:9606	20190314	ARUK-UCL		UniProtKB:Q9H1K1
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9H4A3	WNK1	acts_upstream_of	GO:0018107	PMID:27782176	ISS	UniProtKB:P83741	P	Serine/threonine-protein kinase WNK1	WNK1|HSN2|KDP|KIAA0344|PRKWNK1	protein	taxon:9606	20200119	ARUK-UCL	has_input(UniProtKB:Q9UHW9)	UniProtKB:Q9H4A3
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9H4A3	WNK1	acts_upstream_of_or_within	GO:0018107	PMID:27782176	IMP		P	Serine/threonine-protein kinase WNK1	WNK1|HSN2|KDP|KIAA0344|PRKWNK1	protein	taxon:9606	20200119	ARUK-UCL	has_input(UniProtKB:O95747)	UniProtKB:Q9H4A3
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9H4A3	WNK1	acts_upstream_of_or_within	GO:0018107	PMID:27782176	IMP		P	Serine/threonine-protein kinase WNK1	WNK1|HSN2|KDP|KIAA0344|PRKWNK1	protein	taxon:9606	20200119	ARUK-UCL	has_input(UniProtKB:P55011)	UniProtKB:Q9H4A3
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9H4A3	WNK1	acts_upstream_of_or_within	GO:0018107	PMID:27782176	IMP		P	Serine/threonine-protein kinase WNK1	WNK1|HSN2|KDP|KIAA0344|PRKWNK1	protein	taxon:9606	20200119	ARUK-UCL	has_input(UniProtKB:Q9UEW8)	UniProtKB:Q9H4A3
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9HBJ8	CLTRN	involved_in	GO:0022898	PMID:25534429	IGI	UniProtKB:Q9NP91	P	Collectrin	CLTRN|TMEM27|UNQ679/PRO1312	protein	taxon:9606	20200610	ARUK-UCL	has_input(UniProtKB:Q9NP91),part_of(GO:1905737)	UniProtKB:Q9HBJ8
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9NPH5	NOX4	involved_in	GO:0061098	PMID:27525436	ISS	UniProtKB:Q9JHI8	P	NADPH oxidase 4	NOX4|RENOX	protein	taxon:9606	20230605	ARUK-UCL	occurs_in(CL:0000746),has_input(UniProtKB:P06241),part_of(GO:0006979)	UniProtKB:Q9NPH5
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9NSD5	SLC6A13	acts_upstream_of	GO:0071705	PMID:24842606	IDA		P	Sodium- and chloride-dependent GABA transporter 2	SLC6A13|GAT2	protein	taxon:9606	20200603	ARUK-UCL	has_input(CHEBI:15430)	UniProtKB:Q9NSD5
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9NSD5	SLC6A13	involved_in	GO:0071705	GO_REF:0000024	ISS	UniProtKB:P31646	P	Sodium- and chloride-dependent GABA transporter 2	SLC6A13|GAT2	protein	taxon:9606	20200608	ARUK-UCL	has_input(CHEBI:16344),has_target_start_location(GO:0009897),has_target_end_location(GO:0009898),occurs_in(CL:0000182)	UniProtKB:Q9NSD5
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9NSD5	SLC6A13	involved_in	GO:0071705	GO_REF:0000024	ISS	UniProtKB:P31646	P	Sodium- and chloride-dependent GABA transporter 2	SLC6A13|GAT2	protein	taxon:9606	20200608	ARUK-UCL	has_target_start_location(GO:0009897),has_target_end_location(GO:0009898),has_input(CHEBI:16244)	UniProtKB:Q9NSD5
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9NZ42	PSENEN	involved_in	GO:0010950	PMID:12522139	IMP		P	Gamma-secretase subunit PEN-2	PSENEN|PEN2|MDS033	protein	taxon:9606	20201110	ARUK-UCL	has_input(UniProtKB:P49768)	UniProtKB:Q9NZ42
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9NZ42	PSENEN	involved_in	GO:0010950	PMID:12763021	IGI	UniProtKB:P05067|UniProtKB:P49768	P	Gamma-secretase subunit PEN-2	PSENEN|PEN2|MDS033	protein	taxon:9606	20201110	ARUK-UCL		UniProtKB:Q9NZ42
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9NZC2	TREM2	acts_upstream_of_or_within	GO:0050731	PMID:32514138	IDA		P	Triggering receptor expressed on myeloid cells 2	TREM2	protein	taxon:9606	20210419	ARUK-UCL	occurs_in(CL:0002629),has_input(UniProtKB:P43405),part_of(GO:0071396)	UniProtKB:Q9NZC2
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9NZC2	TREM2	involved_in	GO:0001934	PMID:29518356	ISS	UniProtKB:Q99NH8	P	Triggering receptor expressed on myeloid cells 2	TREM2	protein	taxon:9606	20181212	ARUK-UCL	occurs_in(CL:0000129),has_input(UniProtKB:Q9WV60)	UniProtKB:Q9NZC2
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9NZC2	TREM2	involved_in	GO:0033674	PMID:31902528	IDA		P	Triggering receptor expressed on myeloid cells 2	TREM2	protein	taxon:9606	20210301	ARUK-UCL	has_input(UniProtKB:P43405)	UniProtKB:Q9NZC2
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9NZC2	TREM2	involved_in	GO:0050730	PMID:29518356	ISS	UniProtKB:Q99NH8	P	Triggering receptor expressed on myeloid cells 2	TREM2	protein	taxon:9606	20181212	ARUK-UCL	occurs_in(CL:0000129),has_input(UniProtKB:P48025)	UniProtKB:Q9NZC2
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9NZC2	TREM2	involved_in	GO:1901980	PMID:29518356	ISS	UniProtKB:Q99NH8	P	Triggering receptor expressed on myeloid cells 2	TREM2	protein	taxon:9606	20181212	ARUK-UCL	occurs_in(CL:0000129)	UniProtKB:Q9NZC2
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9UBN7	HDAC6	involved_in	GO:0006476	PMID:28386764	TAS		P	Histone deacetylase 6	HDAC6|KIAA0901|JM21	protein	taxon:9606	20180122	ARUK-UCL	has_input(UniProtKB:P10636)	UniProtKB:Q9UBN7
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9UBN7	HDAC6	involved_in	GO:0033138	PMID:23962722	IMP		P	Histone deacetylase 6	HDAC6|KIAA0901|JM21	protein	taxon:9606	20180126	ARUK-UCL	has_input(UniProtKB:P10636),positively_regulates(GO:0051259)	UniProtKB:Q9UBN7
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9UBN7	HDAC6	involved_in	GO:0034983	PMID:23962722	IMP		P	Histone deacetylase 6	HDAC6|KIAA0901|JM21	protein	taxon:9606	20180126	ARUK-UCL	has_input(UniProtKB:P10636-6),positively_regulates(GO:0051259),positively_regulates(GO:0018105)	UniProtKB:Q9UBN7
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9UBN7	HDAC6	involved_in	GO:0090042	PMID:28386764	TAS		P	Histone deacetylase 6	HDAC6|KIAA0901|JM21	protein	taxon:9606	20180122	ARUK-UCL		UniProtKB:Q9UBN7
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9UEW8	STK39	involved_in	GO:0018107	GO_REF:0000024	ISS	UniProtKB:Q9Z1W9	P	STE20/SPS1-related proline-alanine-rich protein kinase	STK39|PASK|SPAK	protein	taxon:9606	20200119	ARUK-UCL	has_input(UniProtKB:Q924N4)	UniProtKB:Q9UEW8
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9UIG8	SLCO3A1	involved_in	GO:0001934	PMID:24945726	IMP	UniProtKB:Q04206	P	Solute carrier organic anion transporter family member 3A1	SLCO3A1|OATP3A1|OATPD|SLC21A11	protein	taxon:9606	20191127	ARUK-UCL	occurs_in(CL:0002518)	UniProtKB:Q9UIG8
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9UIG8	SLCO3A1	involved_in	GO:0051092	PMID:24945726	IMP		P	Solute carrier organic anion transporter family member 3A1	SLCO3A1|OATP3A1|OATPD|SLC21A11	protein	taxon:9606	20191127	ARUK-UCL	occurs_in(CL:0002518)	UniProtKB:Q9UIG8
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9UL54	TAOK2	involved_in	GO:0031954	PMID:22683681	TAS		P	Serine/threonine-protein kinase TAO2	TAOK2|KIAA0881|MAP3K17|PSK|PSK1|UNQ2971/PRO7431	protein	taxon:9606	20171117	ARUK-UCL		UniProtKB:Q9UL54
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9UL54	TAOK2	involved_in	GO:0032147	PMID:22683681	TAS		P	Serine/threonine-protein kinase TAO2	TAOK2|KIAA0881|MAP3K17|PSK|PSK1|UNQ2971/PRO7431	protein	taxon:9606	20171117	ARUK-UCL	has_input(UniProtKB:Q9UL54)	UniProtKB:Q9UL54
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9UL54	TAOK2	involved_in	GO:0046777	PMID:22683681	TAS		P	Serine/threonine-protein kinase TAO2	TAOK2|KIAA0881|MAP3K17|PSK|PSK1|UNQ2971/PRO7431	protein	taxon:9606	20171117	ARUK-UCL	part_of(GO:0032147)	UniProtKB:Q9UL54
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9UPR5	SLC8A2	acts_upstream_of_or_within	GO:0071902	GO_REF:0000024	ISS	UniProtKB:Q8K596	P	Sodium/calcium exchanger 2	SLC8A2|KIAA1087|NCX2	protein	taxon:9606	20191210	ARUK-UCL	occurs_in(UBERON:0002421),has_input(UniProtKB:Q9UQM7)	UniProtKB:Q9UPR5
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9UPY8	MAPRE3	involved_in	GO:0045860	PMID:26323690	IDA		P	Microtubule-associated protein RP/EB family member 3	MAPRE3	protein	taxon:9606	20171106	ARUK-UCL	has_input(UniProtKB:Q6IQ55)	UniProtKB:Q9UPY8
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9Y6K5	OAS3	involved_in	GO:0060700	PMID:25275129	IDA		P	2'-5'-oligoadenylate synthase 3	OAS3|P/OKcl.4	protein	taxon:9606	20210215	ARUK-UCL	part_of(GO:0051607)	UniProtKB:Q9Y6K5
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1062	abeta-40-42_human	involved_in	GO:2000310	PMID:26224839	TAS		P	Amyloid-beta protein 40/42 complex	beta-amyloid protein 40/42 heterodimer|beta-amyloid protein 40/42 complex|beta-amyloid-40/42 complex|beta amyloid protein 40/42 complex|amyloid-beta-40/42 complex|amyloid beta protein 40/42 complex|amyloid-beta protein 40/42 heterodimer|amyloid-beta-40/42 heterodimer|amyloid beta protein 40/42 heterodimer|beta-amyloid-40/42 heterodimer|beta amyloid protein 40/42 heterodimer|Abeta protein 40/42 complex|APP dimer	protein_complex	taxon:9606	20170831	ARUK-UCL	causally_upstream_of(GO:1905809)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1069	abeta-40_human	involved_in	GO:2000310	PMID:26224839	TAS		P	Amyloid-beta protein 40 complex	beta-amyloid protein 40 homodimer|beta-amyloid protein 40 complex|beta-amyloid-40 complex|beta amyloid protein 40 complex|amyloid-beta-40 complex|amyloid beta protein 40 complex|amyloid-beta protein 40 homodimer|amyloid-beta-40 homodimer|amyloid beta protein 40 homodimer|beta-amyloid-40 homodimer|beta amyloid protein 40 homodimer|APP dimer|Abeta protein 40 complex	protein_complex	taxon:9606	20170831	ARUK-UCL	causally_upstream_of(GO:1905809)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1070	abeta-42_human	involved_in	GO:2000310	PMID:26224839	TAS		P	Amyloid-beta protein 42 complex	beta-amyloid protein 42 homodimer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 homodimer|amyloid-beta-42 homodimer|amyloid beta protein 42 homodimer|beta-amyloid-42 homodimer|beta amyloid protein 42 homodimer|APP dimer|Abeta protein 42 complex	protein_complex	taxon:9606	20170831	ARUK-UCL	causally_upstream_of(GO:1905809)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1120	abeta-40-42-oligomer_human	involved_in	GO:0001934	PMID:29518356	IGI	UniProtKB:Q99NH8	P	Amyloid-beta protein 40/42 oligomeric complex	fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 40/42 heterooligomer|beta-amyloid protein 40/42 complex|beta-amyloid-40/42 complex|beta amyloid protein 40/42 complex|amyloid-beta-40/42 complex|amyloid beta protein 40/42 complex|amyloid-beta protein 40/42 heterooligomer|amyloid-beta-40/42 heterooligomer|amyloid beta protein 40/42 heterooligomer|beta-amyloid-40/42 heterooligomer|beta amyloid protein 40/42 heterooligomer|Abeta protein 40/42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex|pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer	protein_complex	taxon:9606	20181212	ARUK-UCL	occurs_in(CL:0000129),has_input(UniProtKB:P49841)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1120	abeta-40-42-oligomer_human	involved_in	GO:0050731	PMID:29518356	IGI	UniProtKB:Q99NH8	P	Amyloid-beta protein 40/42 oligomeric complex	fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 40/42 heterooligomer|beta-amyloid protein 40/42 complex|beta-amyloid-40/42 complex|beta amyloid protein 40/42 complex|amyloid-beta-40/42 complex|amyloid beta protein 40/42 complex|amyloid-beta protein 40/42 heterooligomer|amyloid-beta-40/42 heterooligomer|amyloid beta protein 40/42 heterooligomer|beta-amyloid-40/42 heterooligomer|beta amyloid protein 40/42 heterooligomer|Abeta protein 40/42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex|pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer	protein_complex	taxon:9606	20181212	ARUK-UCL	occurs_in(CL:0000129),has_input(UniProtKB:P43405)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1120	abeta-40-42-oligomer_human	involved_in	GO:1903609	PMID:29518356	IDA		P	Amyloid-beta protein 40/42 oligomeric complex	fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 40/42 heterooligomer|beta-amyloid protein 40/42 complex|beta-amyloid-40/42 complex|beta amyloid protein 40/42 complex|amyloid-beta-40/42 complex|amyloid beta protein 40/42 complex|amyloid-beta protein 40/42 heterooligomer|amyloid-beta-40/42 heterooligomer|amyloid beta protein 40/42 heterooligomer|beta-amyloid-40/42 heterooligomer|beta amyloid protein 40/42 heterooligomer|Abeta protein 40/42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex|pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer	protein_complex	taxon:9606	20181212	ARUK-UCL	occurs_in(CL:0000129)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1120	abeta-40-42-oligomer_human	involved_in	GO:2000310	PMID:26224839	TAS		P	Amyloid-beta protein 40/42 oligomeric complex	fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 40/42 heterooligomer|beta-amyloid protein 40/42 complex|beta-amyloid-40/42 complex|beta amyloid protein 40/42 complex|amyloid-beta-40/42 complex|amyloid beta protein 40/42 complex|amyloid-beta protein 40/42 heterooligomer|amyloid-beta-40/42 heterooligomer|amyloid beta protein 40/42 heterooligomer|beta-amyloid-40/42 heterooligomer|beta amyloid protein 40/42 heterooligomer|Abeta protein 40/42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex|pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer	protein_complex	taxon:9606	20170831	ARUK-UCL	causally_upstream_of(GO:1905809)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1134	abeta-42-oligomer_human	involved_in	GO:0010800	GO_REF:0000024	ISS	ComplexPortal:CPX-1183	P	Amyloid-beta protein 42 oligomeric complex	pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex	protein_complex	taxon:9606	20170831	ARUK-UCL	has_input(UniProtKB:Q15418),occurs_in(UBERON:0002421)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1134	abeta-42-oligomer_human	involved_in	GO:0032147	PMID:23386614	IGI	UniProtKB:P04925	P	Amyloid-beta protein 42 oligomeric complex	pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex	protein_complex	taxon:9606	20210428	ARUK-UCL	has_input(UniProtKB:P06241),occurs_in(GO:0045121)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1134	abeta-42-oligomer_human	involved_in	GO:0043085	PMID:23386614	IGI	UniProtKB:P04925	P	Amyloid-beta protein 42 oligomeric complex	pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex	protein_complex	taxon:9606	20170626	ARUK-UCL	has_input(UniProtKB:P56817),positively_regulates(GO:0034205)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1134	abeta-42-oligomer_human	involved_in	GO:0050731	PMID:21857966	IDA		P	Amyloid-beta protein 42 oligomeric complex	pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex	protein_complex	taxon:9606	20230517	ARUK-UCL	has_input(UniProtKB:Q9UQM7),occurs_in(CL:0010012)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1134	abeta-42-oligomer_human	involved_in	GO:0050731	PMID:22635104	IDA		P	Amyloid-beta protein 42 oligomeric complex	pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex	protein_complex	taxon:9606	20170906	ARUK-UCL	occurs_in(CL:0000540),has_input(UniProtKB:P08069),occurs_in(GO:0005886)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1134	abeta-42-oligomer_human	involved_in	GO:0050731	PMID:24658113	IDA		P	Amyloid-beta protein 42 oligomeric complex	pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex	protein_complex	taxon:9606	20170627	ARUK-UCL	has_input(UniProtKB:P00519),occurs_in(UBERON:0002421),occurs_in(GO:0043025)|has_input(UniProtKB:P00519),occurs_in(UBERON:0002421),occurs_in(GO:0005634),occurs_in(CL:0000540)|has_input(UniProtKB:P00519),occurs_in(UBERON:0002421),occurs_in(GO:0030425)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1134	abeta-42-oligomer_human	involved_in	GO:0051091	PMID:23921129	IGI	UniProtKB:P05067	P	Amyloid-beta protein 42 oligomeric complex	pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex	protein_complex	taxon:9606	20230517	ARUK-UCL	occurs_in(CL:0010012),part_of(GO:1904646),has_input(UniProtKB:P05412)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1134	abeta-42-oligomer_human	involved_in	GO:0061098	PMID:15190117	IGI	UniProtKB:P05067-PRO_0000000092	P	Amyloid-beta protein 42 oligomeric complex	pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex	protein_complex	taxon:9606	20170614	ARUK-UCL	occurs_in(UBERON:0002421),part_of(GO:0045666)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1134	abeta-42-oligomer_human	involved_in	GO:0061098	PMID:24658113	IDA		P	Amyloid-beta protein 42 oligomeric complex	pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex	protein_complex	taxon:9606	20170627	ARUK-UCL	has_input(UniProtKB:P00519),occurs_in(UBERON:0002421),occurs_in(GO:0043025)|has_input(UniProtKB:P00519),occurs_in(UBERON:0002421),occurs_in(GO:0005634),occurs_in(CL:0000540)|has_input(UniProtKB:P00519),occurs_in(UBERON:0002421),occurs_in(GO:0030425)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1134	abeta-42-oligomer_human	involved_in	GO:0061098	PMID:24658113	IDA		P	Amyloid-beta protein 42 oligomeric complex	pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex	protein_complex	taxon:9606	20170627	ARUK-UCL	has_input(UniProtKB:P54764),occurs_in(UBERON:0002421),occurs_in(CL:0002608)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1134	abeta-42-oligomer_human	involved_in	GO:0061098	PMID:24658113	IGI	UniProtKB:Q03137	P	Amyloid-beta protein 42 oligomeric complex	pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex	protein_complex	taxon:9606	20170627	ARUK-UCL	occurs_in(CL:0002608),has_input(UniProtKB:P00520)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1134	abeta-42-oligomer_human	involved_in	GO:0061907	PMID:20739563	IDA		P	Amyloid-beta protein 42 oligomeric complex	pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex	protein_complex	taxon:9606	20170703	ARUK-UCL	occurs_in(UBERON:0022337),occurs_in(UBERON:0022327)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1134	abeta-42-oligomer_human	involved_in	GO:0150072	PMID:28912710	IC	GO:0010628	P	Amyloid-beta protein 42 oligomeric complex	pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex	protein_complex	taxon:9606	20190909	ARUK-UCL	occurs_in(CL:0000129),part_of(GO:0001774),has_input(UniProtKB:P05089)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1134	abeta-42-oligomer_human	involved_in	GO:1904685	PMID:28912710	IDA		P	Amyloid-beta protein 42 oligomeric complex	pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex	protein_complex	taxon:9606	20190909	ARUK-UCL	happens_during(UBERON:0007222),has_input(UniProtKB:P08253),occurs_in(CL:0000129)|has_input(UniProtKB:P14780),occurs_in(CL:0000129)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1134	abeta-42-oligomer_human	involved_in	GO:2000310	PMID:26224839	TAS		P	Amyloid-beta protein 42 oligomeric complex	pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 42 heterooligomer|beta-amyloid protein 42 complex|beta-amyloid-42 complex|beta amyloid protein 42 complex|amyloid-beta-42 complex|amyloid beta protein 42 complex|amyloid-beta protein 42 heterooligomer|amyloid-beta-42 heterooligomer|amyloid beta protein 42 heterooligomer|beta-amyloid-42 heterooligomer|beta amyloid protein 42 heterooligomer|Abeta protein 42 complex|APP oligomer|Type 1 amyloid-beta oligomer|ADDL complex	protein_complex	taxon:9606	20170831	ARUK-UCL	causally_upstream_of(GO:1905809)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`ComplexPortal	CPX-1180	abeta-40-oligomer_human	involved_in	GO:2000310	PMID:26224839	TAS		P	Amyloid-beta protein 40 oligomeric complex	ADDL complex|pre-fibrillar amyloid-beta oligomer|prefibrillar amyloid-beta oligomer|Type 2 amyloid-beta oligomer|fibrillar amyloid-beta oligomer|Annular protofibril complex|Amyloid-beta fibrils|beta-amyloid protein 40 homooligomer|beta-amyloid protein 40 complex|beta-amyloid-40 complex|beta amyloid protein 40 complex|amyloid-beta-40 complex|amyloid beta protein 40 complex|amyloid-beta protein 40 homooligomer|amyloid-beta-40 homooligomer|amyloid beta protein 40 homooligomer|beta-amyloid-40 heterooligomer|beta amyloid protein 40 homooligomer|Abeta protein 40 complex|APP oligomer|Type 1 amyloid-beta oligomer	protein_complex	taxon:9606	20170831	ARUK-UCL	causally_upstream_of(GO:1905809)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS000003575B_9606	URS000003575B_9606	acts_upstream_of	GO:0001933	PMID:33915734	IDA		P	Homo sapiens (human) hsa-miR-483-5p		miRNA	taxon:9606	20210720	ARUK-UCL	has_input(UniProtKB:P10636)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS000003FD55_9606	URS000003FD55_9606	involved_in	GO:0010951	PMID:24352696	IDA		P	Homo sapiens (human) hsa-miR-339-5p		miRNA	taxon:9606	20200720	ARUK-UCL	has_input(UniProtKB:P56817),causally_upstream_of(GO:1902430)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS000005A8ED_9606	URS000005A8ED_9606	involved_in	GO:0032410	PMID:28411377	IMP		P	Homo sapiens (human) hsa-miR-495-3p		miRNA	taxon:9606	20210518	ARUK-UCL	has_input(UniProtKB:P08183),causally_upstream_of(GO:1905700)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS0000183BED_9606	URS0000183BED_9606	acts_upstream_of_or_within	GO:2000272	PMID:29901200	IDA		P	Homo sapiens (human) hsa-miR-23b-3p		miRNA	taxon:9606	20201016	ARUK-UCL	has_input(UniProtKB:Q14626)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS00001D6BAE_9606	URS00001D6BAE_9606	acts_upstream_of	GO:1902083	PMID:28089352	IDA		P	Homo sapiens (human) hsa-miR-212-3p		miRNA	taxon:9606	20241013	ARUK-UCL	occurs_in(CL:0000540),has_input(UniProtKB:P04406)|occurs_in(CL:0000540),has_input(UniProtKB:Q00535)|occurs_in(CL:0000540),has_input(UniProtKB:O00429)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS00001DC04F_9606	URS00001DC04F_9606	acts_upstream_of	GO:0032410	PMID:28042875	IDA		P	Homo sapiens (human) hsa-miR-1-3p		miRNA	taxon:9606	20210319	ARUK-UCL	has_input(UniProtKB:P08183),part_of(GO:1905700)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS00001E3523_9606	URS00001E3523_9606	involved_in	GO:0001933	PMID:30102687	IDA		P	Homo sapiens (human) hsa-miR-137-3p		miRNA	taxon:9606	20181211	ARUK-UCL	has_input(UniProtKB:P10636),has_input(UniProtKB:P05067-PRO_0000000092),occurs_in(CL:0000031)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS000021202F_9606	URS000021202F_9606	acts_upstream_of	GO:0032410	PMID:23893241	IGI	UniProtKB:P08183	P	Homo sapiens (human) hsa-miR-508-5p		miRNA	taxon:9606	20210210	ARUK-UCL	has_input(UniProtKB:P08183),part_of(GO:1905700)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS000024A59E_9606	URS000024A59E_9606	involved_in	GO:0001934	PMID:19228967	ISS	RNAcentral:URS000024A59E_10116	P	Homo sapiens (human) hsa-miR-128-3p		miRNA	taxon:9606	20180306	ARUK-UCL	has_input(UniProtKB:P10636),occurs_in(CL:0000540)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS000026261D_9606	URS000026261D_9606	acts_upstream_of	GO:0032088	PMID:30233718	IMP		P	Homo sapiens (human) hsa-miR-140-5p		miRNA	taxon:9606	20201102	ARUK-UCL		
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS000028C188_9606	URS000028C188_9606	acts_upstream_of	GO:0051092	PMID:28159925	IGI	UniProtKB:Q04206	P	Homo sapiens (human) hsa-miR-1246		miRNA	taxon:9606	20210716	ARUK-UCL	occurs_in(CL:0000134),part_of(GO:1903265)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS00002E857A_9606	URS00002E857A_9606	acts_upstream_of	GO:0032410	PMID:18645025	IMP		P	Homo sapiens (human) hsa-miR-451a		miRNA	taxon:9606	20210215	ARUK-UCL	part_of(GO:1905700),has_input(UniProtKB:P08183)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS000030BD69_9606	URS000030BD69_9606	acts_upstream_of	GO:0071901	PMID:26330104	IMP		P	Homo sapiens (human) hsa-miR-34a-5p		miRNA	taxon:9606	20200821	ARUK-UCL	has_input(UniProtKB:Q13131),part_of(GO:1902532),occurs_in(CL:0000182)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS0000316FA5_9606	URS0000316FA5_9606	involved_in	GO:0071902	PMID:24027266	ISS	RNAcentral:URS0000316FA5_10116	P	Homo sapiens (human) hsa-miR-26b-5p		miRNA	taxon:9606	20190307	ARUK-UCL	occurs_in(CL:0010012),has_input(UniProtKB:Q00535),has_input(UniProtKB:P10636)|occurs_in(CL:0010012),has_input(UniProtKB:Q00535),has_input(UniProtKB:P06400)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS000032BD73_9606	URS000032BD73_9606	involved_in	GO:0032410	PMID:28881788	IDA		P	Homo sapiens (human) hsa-miR-133b		miRNA	taxon:9606	20211104	ARUK-UCL	has_input(UniProtKB:P33527),causally_upstream_of(GO:1905700)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS00003496BE_9606	URS00003496BE_9606	acts_upstream_of	GO:0032410	PMID:28260112	IGI	UniProtKB:P08183	P	Homo sapiens (human) hsa-miR-9-3p		miRNA	taxon:9606	20210319	ARUK-UCL	has_input(UniProtKB:P08183),part_of(GO:1905700)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS00003B95DA_9606	URS00003B95DA_9606	involved_in	GO:1905919	PMID:24608080	IDA		P	Homo sapiens (human) hsa-miR-27a-3p		miRNA	taxon:9606	20220217	ARUK-UCL	occurs_in(CL:0000517),has_input(UniProtKB:P35610)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS00003D1AE3_9606	URS00003D1AE3_9606	involved_in	GO:0010801	PMID:27343180	IDA		P	Homo sapiens (human) hsa-miR-15a-5p		miRNA	taxon:9606	20181219	ARUK-UCL	has_input(UniProtKB:Q00535),has_input(UniProtKB:P05067),occurs_in(CL:0000540)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS00003D1AE3_9606	URS00003D1AE3_9606	involved_in	GO:0032088	PMID:30365148	IDA		P	Homo sapiens (human) hsa-miR-15a-5p		miRNA	taxon:9606	20181108	ARUK-UCL	occurs_in(CL:0002585),part_of(GO:0071333)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS00003D1AE3_9606	URS00003D1AE3_9606	involved_in	GO:0045736	PMID:27343180	IDA		P	Homo sapiens (human) hsa-miR-15a-5p		miRNA	taxon:9606	20181219	ARUK-UCL	has_input(UniProtKB:Q00535),occurs_in(CL:0000540)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS000040DCFF_9606	URS000040DCFF_9606	acts_upstream_of	GO:0032410	PMID:26626440	IMP		P	Homo sapiens (human) hsa-miR-186-5p		miRNA	taxon:9606	20210210	ARUK-UCL	has_input(UniProtKB:P08183),part_of(GO:1905700)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS0000432971_9606	URS0000432971_9606	acts_upstream_of	GO:0032410	PMID:26924291	IMP		P	Homo sapiens (human) hsa-miR-34b-5p		miRNA	taxon:9606	20210215	ARUK-UCL	part_of(GO:1905700),has_input(UniProtKB:P08183)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS00004449AE_9606	URS00004449AE_9606	involved_in	GO:0050732	PMID:27520374	IDA		P	Homo sapiens (human) hsa-miR-106b-5p		miRNA	taxon:9606	20181219	ARUK-UCL	occurs_in(CL:0000540),has_input(UniProtKB:P10636),has_input(UniProtKB:P06241),part_of(GO:1904646)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS0000476BE1_9606	URS0000476BE1_9606	involved_in	GO:0010801	PMID:27343180	IDA		P	Homo sapiens (human) hsa-miR-103a-3p		miRNA	taxon:9606	20181219	ARUK-UCL	has_input(UniProtKB:Q00535),has_input(UniProtKB:P05067),occurs_in(CL:0000540)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS0000476BE1_9606	URS0000476BE1_9606	involved_in	GO:0045736	PMID:27343180	IDA		P	Homo sapiens (human) hsa-miR-103a-3p		miRNA	taxon:9606	20181219	ARUK-UCL	has_input(UniProtKB:Q00535),occurs_in(CL:0000540)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS00004996E9_9606	URS00004996E9_9606	acts_upstream_of	GO:0032410	PMID:26850595	IGI	UniProtKB:P08183	P	Homo sapiens (human) hsa-miR-873-5p		miRNA	taxon:9606	20210319	ARUK-UCL	has_input(UniProtKB:P08183),part_of(GO:1905700)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS00004BCD9C_9606	URS00004BCD9C_9606	involved_in	GO:0032088	PMID:30365148	IDA		P	Homo sapiens (human) hsa-miR-16-5p		miRNA	taxon:9606	20181108	ARUK-UCL	occurs_in(CL:0002585),part_of(GO:0071333)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS000055128B_9606	URS000055128B_9606	involved_in	GO:1904233	PMID:20436681	IDA		P	Homo sapiens (human) hsa-miR-210-3p		miRNA	taxon:9606	20190314	ARUK-UCL		
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS000059311D_9606	URS000059311D_9606	acts_upstream_of	GO:0051001	PMID:25795136	ISS	RNAcentral:URS000059311D_10116	P	Homo sapiens (human) hsa-miR-27b-3p		miRNA	taxon:9606	20200813	ARUK-UCL	has_input(UniProtKB:P29474),occurs_in(UBERON:0002048)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS000059311D_9606	URS000059311D_9606	involved_in	GO:1905919	PMID:24608080	IDA		P	Homo sapiens (human) hsa-miR-27b-3p		miRNA	taxon:9606	20220217	ARUK-UCL	occurs_in(CL:0000517),has_input(UniProtKB:P35610)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RNAcentral	URS00006054DA_9606	URS00006054DA_9606	acts_upstream_of	GO:1902083	PMID:28089352	IDA		P	Homo sapiens (human) hsa-miR-132-3p		miRNA	taxon:9606	20241013	ARUK-UCL	occurs_in(CL:0000540),has_input(UniProtKB:P04406)|occurs_in(CL:0000540),has_input(UniProtKB:Q00535)|occurs_in(CL:0000540),has_input(UniProtKB:O00429)	
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P51866	PECAM1	involved_in	GO:0001934	PMID:15985432	IMP		P	Platelet endothelial cell adhesion molecule	PECAM1	protein	taxon:9913	20190603	ARUK-UCL	occurs_in(CL:0002544),has_input(UniProtKB:P46196)|has_input(UniProtKB:P29473),occurs_in(CL:0002544)	UniProtKB:P51866
`