# GORULE violations assigned by mgi

## SUMMARY

This report generated on 2024-12-19

## Contents

[gorule-0000008](#gorule-0000008)[No annotations should be made to uninformative high level terms]{}

[gorule-0000020](#gorule-0000020)[Automatic repair of annotations to merged or obsoleted terms]{}

[gorule-0000046](#gorule-0000046)[The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.]{}

[gorule-0000061](#gorule-0000061)[Allowed gene product to term relations (gp2term)]{}

[gorule-0000065](#gorule-0000065)[Annotations to term that are candidates for obsoletion should be removed]{}

## MESSAGES

###gorule-0000008

No annotations should be made to uninformative high level terms

* total: 12
#### Messages
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	O14981	BTAF1	acts_upstream_of_or_within	GO:0035562	PMID:23361013	IMP		P	TATA-binding protein-associated factor 172	BTAF1|TAF172	protein	taxon:9606	20140627	MGI		UniProtKB:O14981
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	O95816	BAG2	acts_upstream_of_or_within	GO:0019538	PMID:9873015	IDA		P	BAG family molecular chaperone regulator 2	BAG2	protein	taxon:9606	20060110	MGI		UniProtKB:O95816
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P01270	PTH	acts_upstream_of_or_within	GO:0009059	PMID:19723499	IDA		P	Parathyroid hormone	PTH	protein	taxon:9606	20100721	MGI		UniProtKB:P01270
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P06400	RB1	acts_upstream_of_or_within	GO:2000679	PMID:25100735	IDA		P	Retinoblastoma-associated protein	RB1	protein	taxon:9606	20160330	MGI		UniProtKB:P06400
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P12644	BMP4	acts_upstream_of_or_within	GO:0032092	PMID:23610558	IDA		P	Bone morphogenetic protein 4	BMP4|BMP2B|DVR4	protein	taxon:9606	20131218	MGI		UniProtKB:P12644
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q12774	ARHGEF5	acts_upstream_of_or_within	GO:0043087	PMID:21525037	IDA		P	Rho guanine nucleotide exchange factor 5	ARHGEF5|TIM	protein	taxon:9606	20120529	MGI		UniProtKB:Q12774
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q5VTB9	RNF220	acts_upstream_of_or_within	GO:2000677	PMID:32094113	IGI	UniProtKB:Q9NQZ6	P	E3 ubiquitin-protein ligase RNF220	RNF220|C1orf164	protein	taxon:9606	20210810	MGI		UniProtKB:Q5VTB9
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q6B0I6	KDM4D	acts_upstream_of_or_within	GO:0035563	PMID:24550317	IMP		P	Lysine-specific demethylase 4D	KDM4D|JHDM3D|JMJD2D	protein	taxon:9606	20150819	MGI		UniProtKB:Q6B0I6
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q96L73	NSD1	acts_upstream_of_or_within	GO:1903025	PMID:20837538	IMP		P	Histone-lysine N-methyltransferase, H3 lysine-36 specific	NSD1|ARA267|KMT3B	protein	taxon:9606	20150406	MGI		UniProtKB:Q96L73
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q9H8T0	AKTIP	acts_upstream_of_or_within	GO:0032092	PMID:14749367	IDA		P	AKT-interacting protein	AKTIP|FTS	protein	taxon:9606	20091109	MGI		UniProtKB:Q9H8T0
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q9NQZ6	ZC4H2	acts_upstream_of_or_within	GO:2000677	PMID:32094113	IGI	UniProtKB:Q5VTB9	P	Zinc finger C4H2 domain-containing protein	ZC4H2|HCA127|KIAA1166	protein	taxon:9606	20210805	MGI		UniProtKB:Q9NQZ6
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q9NXS2	QPCTL	acts_upstream_of_or_within	GO:0017186	PMID:18486145	IDA		P	Glutaminyl-peptide cyclotransferase-like protein	QPCTL	protein	taxon:9606	20120315	MGI		UniProtKB:Q9NXS2
`

###gorule-0000020

Automatic repair of annotations to merged or obsoleted terms

* total: 18
#### Messages
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	Q8IW19	APLF	acts_upstream_of_or_within	GO:0051106	PMID:21211721	IGI	UniProtKB:Q9Y6F1	P	Aprataxin and PNK-like factor	APLF|C2orf13|PALF|XIP1	protein	taxon:9606	20131119	MGI		UniProtKB:Q8IW19
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	Q9Y6F1	PARP3	acts_upstream_of_or_within	GO:0051106	PMID:21211721	IGI	UniProtKB:Q8IW19	P	Protein mono-ADP-ribosyltransferase PARP3	PARP3|ADPRT3|ADPRTL3	protein	taxon:9606	20131119	MGI		UniProtKB:Q9Y6F1
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	O75915	ARL6IP5	acts_upstream_of_or_within	GO:0071407	PMID:12562531	IDA		P	PRA1 family protein 3	ARL6IP5|DERP11|JWA|PRA2|PRAF3|HSPC127	protein	taxon:9606	20200903	MGI		UniProtKB:O75915
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	P04798	CYP1A1	acts_upstream_of_or_within	GO:0071407	PMID:23275542	IDA		P	Cytochrome P450 1A1	CYP1A1	protein	taxon:9606	20140331	MGI		UniProtKB:P04798
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	P43005	SLC1A1	acts_upstream_of_or_within	GO:0071407	PMID:12562531	IDA		P	Excitatory amino acid transporter 3	SLC1A1|EAAC1|EAAT3|HEAAC1	protein	taxon:9606	20200903	MGI		UniProtKB:P43005
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	Q16678	CYP1B1	acts_upstream_of_or_within	GO:0071407	PMID:23275542	IDA		P	Cytochrome P450 1B1	CYP1B1	protein	taxon:9606	20140331	MGI		UniProtKB:Q16678
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	Q7Z3E1	TIPARP	acts_upstream_of_or_within	GO:0071407	PMID:23275542	IDA		P	Protein mono-ADP-ribosyltransferase TIPARP	TIPARP|PARP7	protein	taxon:9606	20140331	MGI		UniProtKB:Q7Z3E1
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	P59046	NLRP12	acts_upstream_of_or_within	GO:2000116	PMID:12019269	IDA		P	NACHT, LRR and PYD domains-containing protein 12	NLRP12|NALP12|PYPAF7|RNO	protein	taxon:9606	20140417	MGI		UniProtKB:P59046
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	O00291	HIP1	acts_upstream_of_or_within	GO:2001056	PMID:11788820	IDA		P	Huntingtin-interacting protein 1	HIP1	protein	taxon:9606	20060131	MGI		UniProtKB:O00291
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	O95150	TNFSF15	acts_upstream_of_or_within	GO:2001056	PMID:11911831	IDA		P	Tumor necrosis factor ligand superfamily member 15	TNFSF15|TL1|VEGI	protein	taxon:9606	20030418	MGI		UniProtKB:O95150
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	P48023	FASLG	acts_upstream_of_or_within	GO:2001056	PMID:19364818	IGI	UniProtKB:P18406	P	Tumor necrosis factor ligand superfamily member 6	FASLG|APT1LG1|CD95L|FASL|TNFSF6	protein	taxon:9606	20101222	MGI		UniProtKB:P48023
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	Q70EL3	USP50	acts_upstream_of_or_within	GO:2001056	PMID:28094437	IMP		P	Ubiquitin carboxyl-terminal hydrolase 50	USP50	protein	taxon:9606	20180802	MGI		UniProtKB:Q70EL3
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	Q9NWB7	IFT57	acts_upstream_of_or_within	GO:2001056	PMID:11788820	IDA		P	Intraflagellar transport protein 57 homolog	IFT57|DERP8|ESRRBL1|HIPPI	protein	taxon:9606	20030627	MGI		UniProtKB:Q9NWB7
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	Q9Y239	NOD1	acts_upstream_of_or_within	GO:2001056	PMID:10329646	IDA		P	Nucleotide-binding oligomerization domain-containing protein 1	NOD1|CARD4	protein	taxon:9606	20101104	MGI		UniProtKB:Q9Y239
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	Q9Y239	NOD1	acts_upstream_of_or_within	GO:2001056	PMID:10329646	IDA		P	Nucleotide-binding oligomerization domain-containing protein 1	NOD1|CARD4	protein	taxon:9606	20130715	MGI		UniProtKB:Q9Y239
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB	Q58WW2	DCAF6	enables	GO:0030374	PMID:15784617	IDA		F	DDB1- and CUL4-associated factor 6	DCAF6|IQWD1|MSTP055	protein	taxon:9606	20080814	MGI		UniProtKB:Q58WW2
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB	Q8IX12	CCAR1	enables	GO:0030374	PMID:18722177	IGI	UniProtKB:P03372	F	Cell division cycle and apoptosis regulator protein 1	CCAR1|CARP1|DIS	protein	taxon:9606	20120320	MGI		UniProtKB:Q8IX12
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB	Q9BQA1	WDR77	enables	GO:0030374	PMID:12972618	IGI	UniProtKB:P10275	F	Methylosome protein WDR77	WDR77|MEP50|WD45|HKMT1069|Nbla10071	protein	taxon:9606	20090731	MGI		UniProtKB:Q9BQA1
`

###gorule-0000046

The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

* total: 13
#### Messages
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	O14732	IMPA2	enables	GO:0042803	PMID:17068342	IDA		F	Inositol monophosphatase 2	IMPA2|IMP.18P	protein	taxon:9606	20091009	MGI		UniProtKB:O14732
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P20023	CR2	enables	GO:0042803	PMID:11728339	IDA		F	Complement receptor type 2	CR2|C3DR	protein	taxon:9606	20110203	MGI		UniProtKB:P20023
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P21266	GSTM3	enables	GO:0042803	PMID:9545290	IDA		F	Glutathione S-transferase Mu 3	GSTM3|GST5	protein	taxon:9606	20120716	MGI		UniProtKB:P21266
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P29218	IMPA1	enables	GO:0042803	PMID:17068342	IDA		F	Inositol monophosphatase 1	IMPA1|IMPA	protein	taxon:9606	20091009	MGI		UniProtKB:P29218
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P51636	CAV2	enables	GO:0042803	PMID:8552590	IDA		F	Caveolin-2	CAV2	protein	taxon:9606	20101102	MGI		UniProtKB:P51636
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P57052	RBM11	enables	GO:0042803	PMID:21984414	IDA		F	Splicing regulator RBM11	RBM11	protein	taxon:9606	20131209	MGI		UniProtKB:P57052
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q13043	STK4	enables	GO:0042803	PMID:11805089	IDA		F	Serine/threonine-protein kinase 4	STK4|KRS2|MST1	protein	taxon:9606	20060707	MGI		UniProtKB:Q13043
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q15517	CDSN	enables	GO:0042803	PMID:15086562	IDA		F	Corneodesmosin	CDSN	protein	taxon:9606	20060111	MGI		UniProtKB:Q15517
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q16760	DGKD	enables	GO:0042803	PMID:12200442	IDA		F	Diacylglycerol kinase delta	DGKD|KIAA0145	protein	taxon:9606	20060131	MGI		UniProtKB:Q16760
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q70YC4	ZNF365	enables	GO:0042803	PMID:16617106	IDA		F	Talanin	ZNF365|KIAA0844	protein	taxon:9606	20151028	MGI		UniProtKB:Q70YC4
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q96C23	GALM	NOT|enables	GO:0042803	PMID:12753898	IDA		F	Galactose mutarotase	GALM|BLOCK25	protein	taxon:9606	20191114	MGI		UniProtKB:Q96C23
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q96Q42	ALS2	acts_upstream_of_or_within	GO:0051260	PMID:15247254	IDA		P	Alsin	ALS2|ALS2CR6|KIAA1563	protein	taxon:9606	20191112	MGI		UniProtKB:Q96Q42
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	O57337	HES1	enables	GO:0042803	PMID:11076679	IDA		F	Transcription factor HES-1	HES1|HAIRY1	protein	taxon:9031	20151105	MGI		UniProtKB:O57337
`

###gorule-0000061

Allowed gene product to term relations (gp2term)

* total: 1
#### Messages
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: BFO:0000050 should be one of RO:0002432, RO:0001025, RO:0002325. Repaired to RO:0001025--`UniProtKB	Q15049	MLC1	part_of	GO:0005886	PMID:21419380	IDA		C	Membrane protein MLC1	MLC1|KIAA0027|WKL1	protein	taxon:9606	20240719	MGI	part_of(CL:0000127)	UniProtKB:Q15049
`

###gorule-0000065

Annotations to term that are candidates for obsoletion should be removed

* total: 131
#### Messages
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O00206	TLR4	acts_upstream_of_or_within	GO:0051092	PMID:12594207	IDA		P	Toll-like receptor 4	TLR4	protein	taxon:9606	20090913	MGI		UniProtKB:O00206
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O00743	PPP6C	acts_upstream_of_or_within	GO:0006470	PMID:16716191	IDA		P	Serine/threonine-protein phosphatase 6 catalytic subunit	PPP6C|PPP6	protein	taxon:9606	20070305	MGI		UniProtKB:O00743
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O14744	PRMT5	acts_upstream_of_or_within	GO:0035246	PMID:15369763	IDA		P	Protein arginine N-methyltransferase 5	PRMT5|HRMT1L5|IBP72|JBP1|SKB1	protein	taxon:9606	20050506	MGI		UniProtKB:O14744
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O14920	IKBKB	acts_upstream_of_or_within	GO:0051092	PMID:15790681	IDA		P	Inhibitor of nuclear factor kappa-B kinase subunit beta	IKBKB|IKKB	protein	taxon:9606	20051028	MGI		UniProtKB:O14920
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O14965	AURKA	acts_upstream_of_or_within	GO:0006468	PMID:21600873	IDA		P	Aurora kinase A	AURKA|AIK|AIRK1|ARK1|AURA|AYK1|BTAK|IAK1|STK15|STK6	protein	taxon:9606	20130920	MGI		UniProtKB:O14965
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O43181	NDUFS4	acts_upstream_of_or_within	GO:0001932	PMID:11165261	IMP		P	NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial	NDUFS4	protein	taxon:9606	20070207	MGI		UniProtKB:O43181
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O60260	PRKN	acts_upstream_of_or_within	GO:0033132	PMID:24187134	IDA		P	E3 ubiquitin-protein ligase parkin	PRKN|PARK2	protein	taxon:9606	20140407	MGI		UniProtKB:O60260
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O60603	TLR2	acts_upstream_of_or_within	GO:0051092	PMID:12594207	IDA		P	Toll-like receptor 2	TLR2|TIL4	protein	taxon:9606	20090913	MGI		UniProtKB:O60603
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O94885	SASH1	acts_upstream_of_or_within	GO:0043507	PMID:23776175	IMP		P	SAM and SH3 domain-containing protein 1	SASH1|KIAA0790|PEPE1	protein	taxon:9606	20140304	MGI		UniProtKB:O94885
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O95150	TNFSF15	acts_upstream_of_or_within	GO:0007250	PMID:11911831	IDA		P	Tumor necrosis factor ligand superfamily member 15	TNFSF15|TL1|VEGI	protein	taxon:9606	20030418	MGI		UniProtKB:O95150
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O95271	TNKS	acts_upstream_of_or_within	GO:0018105	PMID:17026964	IDA		P	Poly [ADP-ribose] polymerase tankyrase-1	TNKS|PARP5A|PARPL|TIN1|TINF1|TNKS1	protein	taxon:9606	20071015	MGI		UniProtKB:O95271
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O95271	TNKS	acts_upstream_of_or_within	GO:0018107	PMID:17026964	IDA		P	Poly [ADP-ribose] polymerase tankyrase-1	TNKS|PARP5A|PARPL|TIN1|TINF1|TNKS1	protein	taxon:9606	20071015	MGI		UniProtKB:O95271
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O95352	ATG7	acts_upstream_of_or_within	GO:0006497	PMID:12890687	IDA		P	Ubiquitin-like modifier-activating enzyme ATG7	ATG7|APG7L	protein	taxon:9606	20210413	MGI		UniProtKB:O95352
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O95352	ATG7	acts_upstream_of_or_within	GO:0031401	PMID:12890687	IDA		P	Ubiquitin-like modifier-activating enzyme ATG7	ATG7|APG7L	protein	taxon:9606	20210413	MGI		UniProtKB:O95352
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P00519	ABL1	acts_upstream_of_or_within	GO:0051444	PMID:20823226	IDA		P	Tyrosine-protein kinase ABL1	ABL1|ABL|JTK7	protein	taxon:9606	20140711	MGI		UniProtKB:P00519
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P01375	TNF	acts_upstream_of_or_within	GO:0051092	PMID:15790681	IDA		P	Tumor necrosis factor	TNF|TNFA|TNFSF2	protein	taxon:9606	20051028	MGI		UniProtKB:P01375
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P01579	IFNG	acts_upstream_of_or_within	GO:0033141	PMID:16280321	IDA		P	Interferon gamma	IFNG	protein	taxon:9606	20090324	MGI		UniProtKB:P01579
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P01579	IFNG	acts_upstream_of_or_within	GO:0042531	PMID:16280321	IDA		P	Interferon gamma	IFNG	protein	taxon:9606	20170417	MGI		UniProtKB:P01579
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P04629	NTRK1	acts_upstream_of_or_within	GO:0038083	PMID:27655914	IDA		P	High affinity nerve growth factor receptor	NTRK1|MTC|TRK|TRKA	protein	taxon:9606	20180118	MGI		UniProtKB:P04629-2
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05231	IL6	acts_upstream_of_or_within	GO:0033138	PMID:7508917	IDA		P	Interleukin-6	IL6|IFNB2	protein	taxon:9606	20101104	MGI		UniProtKB:P05231
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05231	IL6	acts_upstream_of_or_within	GO:0050731	PMID:7508917	IDA		P	Interleukin-6	IL6|IFNB2	protein	taxon:9606	20101104	MGI		UniProtKB:P05231
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05305	EDN1	involved_in	GO:2001259	PMID:30990108	IDA		P	Endothelin-1	EDN1	protein	taxon:9606	20210720	MGI		UniProtKB:P05305
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P07237	P4HB	acts_upstream_of_or_within	GO:0018401	PMID:7753822	IDA		P	Protein disulfide-isomerase	P4HB|ERBA2L|PDI|PDIA1|PO4DB	protein	taxon:9606	20060111	MGI		UniProtKB:P07237
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P08069	IGF1R	acts_upstream_of_or_within	GO:0038083	PMID:19545541	IMP		P	Insulin-like growth factor 1 receptor	IGF1R	protein	taxon:9606	20140418	MGI		UniProtKB:P08069
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P12643	BMP2	acts_upstream_of_or_within	GO:0001934	PMID:17472960	IDA		P	Bone morphogenetic protein 2	BMP2|BMP2A	protein	taxon:9606	20090324	MGI		UniProtKB:P12643
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P12643	BMP2	acts_upstream_of_or_within	GO:0010922	PMID:9213002	IDA		P	Bone morphogenetic protein 2	BMP2|BMP2A	protein	taxon:9606	20100406	MGI		UniProtKB:P12643
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P12644	BMP4	acts_upstream_of_or_within	GO:0001934	PMID:14749725	IDA		P	Bone morphogenetic protein 4	BMP4|BMP2B|DVR4	protein	taxon:9606	20101102	MGI		UniProtKB:P12644
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P12931	SRC	acts_upstream_of_or_within	GO:0018108	PMID:22732588	IDA		P	Proto-oncogene tyrosine-protein kinase Src	SRC|SRC1	protein	taxon:9606	20130107	MGI		UniProtKB:P12931
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P13385	CRIPTO	acts_upstream_of_or_within	GO:0043406	PMID:9013573	IDA		P	Protein Cripto	CRIPTO|CRIPTO-1|TDGF1	protein	taxon:9606	20210512	MGI		UniProtKB:P13385
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P13725	OSM	acts_upstream_of_or_within	GO:0033138	PMID:7508917	IDA		P	Oncostatin-M	OSM	protein	taxon:9606	20101104	MGI		UniProtKB:P13725
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P13725	OSM	acts_upstream_of_or_within	GO:0050731	PMID:7508917	IDA		P	Oncostatin-M	OSM	protein	taxon:9606	20101104	MGI		UniProtKB:P13725
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P14678	SNRPB	acts_upstream_of_or_within	GO:0006479	PMID:18495660	IDA		P	Small nuclear ribonucleoprotein-associated proteins B and B'	SNRPB|COD|SNRPB1	protein	taxon:9606	20150204	MGI		UniProtKB:P14678
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P15018	LIF	acts_upstream_of_or_within	GO:0033138	PMID:7508917	IDA		P	Leukemia inhibitory factor	LIF|HILDA	protein	taxon:9606	20101104	MGI		UniProtKB:P15018
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P15018	LIF	acts_upstream_of_or_within	GO:0050731	PMID:7508917	IDA		P	Leukemia inhibitory factor	LIF|HILDA	protein	taxon:9606	20101104	MGI		UniProtKB:P15018
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P15170	GSPT1	acts_upstream_of_or_within	GO:0006479	PMID:18539146	IDA		P	Eukaryotic peptide chain release factor GTP-binding subunit ERF3A	GSPT1|ERF3A	protein	taxon:9606	20090611	MGI		UniProtKB:P15170
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P15336	ATF2	involved_in	GO:0018107	PMID:17267404	IDA		P	Cyclic AMP-dependent transcription factor ATF-2	ATF2|CREB2|CREBP1	protein	taxon:9606	20210602	MGI		UniProtKB:P15336
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P16220	CREB1	acts_upstream_of_or_within	GO:0006468	PMID:8798441	IDA		P	Cyclic AMP-responsive element-binding protein 1	CREB1	protein	taxon:9606	20090324	MGI		UniProtKB:P16220
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P17936	IGFBP3	acts_upstream_of_or_within	GO:0001933	PMID:17591901	IDA		P	Insulin-like growth factor-binding protein 3	IGFBP3|IBP3	protein	taxon:9606	20070920	MGI		UniProtKB:P17936
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P17936	IGFBP3	acts_upstream_of_or_within	GO:0006468	PMID:17434920	IDA		P	Insulin-like growth factor-binding protein 3	IGFBP3|IBP3	protein	taxon:9606	20070920	MGI		UniProtKB:P17936
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P20340	RAB6A	acts_upstream_of_or_within	GO:0018125	PMID:11121396	IDA		P	Ras-related protein Rab-6A	RAB6A|RAB6	protein	taxon:9606	20090324	MGI		UniProtKB:P20340
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P20809	IL11	acts_upstream_of_or_within	GO:0033138	PMID:7508917	IDA		P	Interleukin-11	IL11	protein	taxon:9606	20101104	MGI		UniProtKB:P20809
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P20809	IL11	acts_upstream_of_or_within	GO:0050731	PMID:7508917	IDA		P	Interleukin-11	IL11	protein	taxon:9606	20101104	MGI		UniProtKB:P20809
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P21359	NF1	acts_upstream_of_or_within	GO:0043547	PMID:16648142	IMP		P	Neurofibromin	NF1	protein	taxon:9606	20070212	MGI		UniProtKB:P21359
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P24864	CCNE1	acts_upstream_of_or_within	GO:0006468	PMID:10500095	IMP		P	G1/S-specific cyclin-E1	CCNE1|CCNE	protein	taxon:9606	20120418	MGI		UniProtKB:P24864
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P25101	EDNRA	involved_in	GO:2001259	PMID:30990108	IDA		P	Endothelin-1 receptor	EDNRA|ETA|ETRA	protein	taxon:9606	20210720	MGI		UniProtKB:P25101
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P25963	NFKBIA	acts_upstream_of_or_within	GO:0032088	PMID:11931770	IDA		P	NF-kappa-B inhibitor alpha	NFKBIA|IKBA|MAD3|NFKBI	protein	taxon:9606	20101104	MGI		UniProtKB:P25963
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P27037	ACVR2A	acts_upstream_of_or_within	GO:0001934	PMID:17472960	IMP		P	Activin receptor type-2A	ACVR2A|ACVR2	protein	taxon:9606	20101102	MGI		UniProtKB:P27037
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P31749	AKT1	acts_upstream_of_or_within	GO:0006468	PMID:14749367	IDA		P	RAC-alpha serine/threonine-protein kinase	AKT1|PKB|RAC	protein	taxon:9606	20070601	MGI		UniProtKB:P31749
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P36873	PPP1CC	acts_upstream_of_or_within	GO:0006470	PMID:22801782	IMP		P	Serine/threonine-protein phosphatase PP1-gamma catalytic subunit	PPP1CC	protein	taxon:9606	20140624	MGI		UniProtKB:P36873
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P38936	CDKN1A	acts_upstream_of_or_within	GO:0045860	PMID:22869755	IDA		P	Cyclin-dependent kinase inhibitor 1	CDKN1A|CAP20|CDKN1|CIP1|MDA6|PIC1|SDI1|WAF1	protein	taxon:9606	20160728	MGI		UniProtKB:P38936
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P42771	CDKN2A	acts_upstream_of_or_within	GO:0045736	PMID:7739547	IDA		P	Cyclin-dependent kinase inhibitor 2A	CDKN2A|CDKN2|MTS1	protein	taxon:9606	20160613	MGI		UniProtKB:P42771
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P43378	PTPN9	acts_upstream_of_or_within	GO:0035335	PMID:27655914	IDA		P	Tyrosine-protein phosphatase non-receptor type 9	PTPN9	protein	taxon:9606	20180118	MGI		UniProtKB:P43378
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P43403	ZAP70	acts_upstream_of_or_within	GO:0018108	PMID:22732588	IDA		P	Tyrosine-protein kinase ZAP-70	ZAP70|SRK	protein	taxon:9606	20130107	MGI		UniProtKB:P43403
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P43403	ZAP70	acts_upstream_of_or_within	GO:0018108	PMID:23620790	IMP		P	Tyrosine-protein kinase ZAP-70	ZAP70|SRK	protein	taxon:9606	20140409	MGI		UniProtKB:P43403
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P43405	SYK	acts_upstream_of_or_within	GO:0051090	PMID:23071339	IMP		P	Tyrosine-protein kinase SYK	SYK	protein	taxon:9606	20141001	MGI		UniProtKB:P43405
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P45983	MAPK8	acts_upstream_of_or_within	GO:0007258	PMID:14967141	IDA		P	Mitogen-activated protein kinase 8	MAPK8|JNK1|PRKM8|SAPK1|SAPK1C	protein	taxon:9606	20101104	MGI		UniProtKB:P45983
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P49841	GSK3B	acts_upstream_of_or_within	GO:0018105	PMID:11104755	IDA		P	Glycogen synthase kinase-3 beta	GSK3B	protein	taxon:9606	20071221	MGI		UniProtKB:P49841
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P49841	GSK3B	acts_upstream_of_or_within	GO:0018105	PMID:14744935	IDA		P	Glycogen synthase kinase-3 beta	GSK3B	protein	taxon:9606	20101102	MGI		UniProtKB:P49841
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P50749	RASSF2	acts_upstream_of_or_within	GO:0031954	PMID:19962960	IDA		P	Ras association domain-containing protein 2	RASSF2|CENP-34|KIAA0168	protein	taxon:9606	20150701	MGI		UniProtKB:P50749
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P50749	RASSF2	acts_upstream_of_or_within	GO:0033137	PMID:19962960	IDA		P	Ras association domain-containing protein 2	RASSF2|CENP-34|KIAA0168	protein	taxon:9606	20150701	MGI		UniProtKB:P50749
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P50749	RASSF2	acts_upstream_of_or_within	GO:0045860	PMID:19962960	IDA		P	Ras association domain-containing protein 2	RASSF2|CENP-34|KIAA0168	protein	taxon:9606	20150701	MGI		UniProtKB:P50749
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P50750	CDK9	acts_upstream_of_or_within	GO:0006468	PMID:16109376	IDA		P	Cyclin-dependent kinase 9	CDK9|CDC2L4|TAK	protein	taxon:9606	20061106	MGI		UniProtKB:P50750
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P51617	IRAK1	acts_upstream_of_or_within	GO:0046777	PMID:12054681	IDA		P	Interleukin-1 receptor-associated kinase 1	IRAK1|IRAK	protein	taxon:9606	20101104	MGI		UniProtKB:P51617
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P56539	CAV3	acts_upstream_of_or_within	GO:0051394	PMID:20472890	IMP		P	Caveolin-3	CAV3	protein	taxon:9606	20120723	MGI		UniProtKB:P56539
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P61925	PKIA	acts_upstream_of_or_within	GO:2000480	PMID:7905001	IDA		P	cAMP-dependent protein kinase inhibitor alpha	PKIA|PRKACN1	protein	taxon:9606	20140514	MGI		UniProtKB:P61925
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P62136	PPP1CA	acts_upstream_of_or_within	GO:0006470	PMID:22801782	IMP		P	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	PPP1CA|PPP1A	protein	taxon:9606	20140624	MGI		UniProtKB:P62136
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P62318	SNRPD3	acts_upstream_of_or_within	GO:0006479	PMID:18495660	IDA		P	Small nuclear ribonucleoprotein Sm D3	SNRPD3	protein	taxon:9606	20150204	MGI		UniProtKB:P62318
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P62495	ETF1	acts_upstream_of_or_within	GO:0006479	PMID:18539146	IDA		P	Eukaryotic peptide chain release factor subunit 1	ETF1|ERF1|RF1|SUP45L1	protein	taxon:9606	20090609	MGI		UniProtKB:P62495
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P78527	PRKDC	acts_upstream_of_or_within	GO:0018105	PMID:15194694	IDA		P	DNA-dependent protein kinase catalytic subunit	PRKDC|HYRC|HYRC1	protein	taxon:9606	20101104	MGI		UniProtKB:P78527
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q04206	RELA	acts_upstream_of_or_within	GO:0051092	PMID:15790681	IDA		P	Transcription factor p65	RELA|NFKB3	protein	taxon:9606	20051021	MGI		UniProtKB:Q04206
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q0VD86	INCA1	acts_upstream_of_or_within	GO:0045736	PMID:21540187	IDA		P	Protein INCA1	INCA1|HSD45	protein	taxon:9606	20130107	MGI		UniProtKB:Q0VD86
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q13043	STK4	acts_upstream_of_or_within	GO:0001934	PMID:19962960	IDA		P	Serine/threonine-protein kinase 4	STK4|KRS2|MST1	protein	taxon:9606	20150701	MGI		UniProtKB:Q13043
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q13043	STK4	acts_upstream_of_or_within	GO:0006468	PMID:11805089	IDA		P	Serine/threonine-protein kinase 4	STK4|KRS2|MST1	protein	taxon:9606	20060707	MGI		UniProtKB:Q13043
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q13043	STK4	acts_upstream_of_or_within	GO:0033138	PMID:19962960	IDA		P	Serine/threonine-protein kinase 4	STK4|KRS2|MST1	protein	taxon:9606	20150701	MGI		UniProtKB:Q13043
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q13043	STK4	acts_upstream_of_or_within	GO:0046777	PMID:11805089	IDA		P	Serine/threonine-protein kinase 4	STK4|KRS2|MST1	protein	taxon:9606	20060707	MGI		UniProtKB:Q13043
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q13177	PAK2	acts_upstream_of_or_within	GO:0006468	PMID:11805089	IDA		P	Serine/threonine-protein kinase PAK 2	PAK2	protein	taxon:9606	20060707	MGI		UniProtKB:Q13177
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q13177	PAK2	acts_upstream_of_or_within	GO:0046777	PMID:11805089	IDA		P	Serine/threonine-protein kinase PAK 2	PAK2	protein	taxon:9606	20060707	MGI		UniProtKB:Q13177
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q13315	ATM	acts_upstream_of_or_within	GO:0036289	PMID:24550317	IMP		P	Serine-protein kinase ATM	ATM	protein	taxon:9606	20150819	MGI		UniProtKB:Q13315
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q13526	PIN1	acts_upstream_of_or_within	GO:0001934	PMID:19638580	IGI	UniProtKB:P53350	P	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	PIN1	protein	taxon:9606	20120203	MGI		UniProtKB:Q13526
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q13627	DYRK1A	acts_upstream_of_or_within	GO:0018108	PMID:9748265	IDA		P	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	DYRK1A|DYRK|MNB|MNBH	protein	taxon:9606	20020402	MGI		UniProtKB:Q13627
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q14149	MORC3	acts_upstream_of_or_within	GO:0006468	PMID:17332504	IDA		P	MORC family CW-type zinc finger protein 3	MORC3|KIAA0136|NXP2|ZCWCC3	protein	taxon:9606	20080111	MGI		UniProtKB:Q14149
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q14149	MORC3	acts_upstream_of_or_within	GO:0018105	PMID:17332504	IDA		P	MORC family CW-type zinc finger protein 3	MORC3|KIAA0136|NXP2|ZCWCC3	protein	taxon:9606	20080111	MGI		UniProtKB:Q14149
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q15831	STK11	acts_upstream_of_or_within	GO:0032147	PMID:18854309	IDA		P	Serine/threonine-protein kinase STK11	STK11|LKB1|PJS	protein	taxon:9606	20130702	MGI		UniProtKB:Q15831-1
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q15831	STK11	acts_upstream_of_or_within	GO:0032147	PMID:18854309	IDA		P	Serine/threonine-protein kinase STK11	STK11|LKB1|PJS	protein	taxon:9606	20130702	MGI		UniProtKB:Q15831-2
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q5S007	LRRK2	acts_upstream_of_or_within	GO:0034260	PMID:22423108	IDA		P	Leucine-rich repeat serine/threonine-protein kinase 2	LRRK2|PARK8	protein	taxon:9606	20120607	MGI		UniProtKB:Q5S007
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q5SQI0	ATAT1	acts_upstream_of_or_within	GO:0071929	PMID:23071314	IDA		P	Alpha-tubulin N-acetyltransferase 1	ATAT1|C6orf134|MEC17|Nbla00487	protein	taxon:9606	20140707	MGI		UniProtKB:Q5SQI0
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q5VTB9	RNF220	acts_upstream_of_or_within	GO:0051091	PMID:32094113	IGI	UniProtKB:Q9NQZ6	P	E3 ubiquitin-protein ligase RNF220	RNF220|C1orf164	protein	taxon:9606	20210810	MGI		UniProtKB:Q5VTB9
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q6B0I6	KDM4D	acts_upstream_of_or_within	GO:0001932	PMID:24550317	IMP		P	Lysine-specific demethylase 4D	KDM4D|JHDM3D|JMJD2D	protein	taxon:9606	20150819	MGI		UniProtKB:Q6B0I6
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q6TCH7	PAQR3	acts_upstream_of_or_within	GO:0001933	PMID:17724343	IDA		P	Progestin and adipoQ receptor family member 3	PAQR3	protein	taxon:9606	20131030	MGI		UniProtKB:Q6TCH7
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q6TCH7	PAQR3	acts_upstream_of_or_within	GO:0033137	PMID:17724343	IDA		P	Progestin and adipoQ receptor family member 3	PAQR3	protein	taxon:9606	20131030	MGI		UniProtKB:Q6TCH7
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q6TCH7	PAQR3	acts_upstream_of_or_within	GO:0043407	PMID:17724343	IDA		P	Progestin and adipoQ receptor family member 3	PAQR3	protein	taxon:9606	20131030	MGI		UniProtKB:Q6TCH7
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q6ZSY5	PPP1R3F	acts_upstream_of_or_within	GO:2000465	PMID:21668450	IDA		P	Protein phosphatase 1 regulatory subunit 3F	PPP1R3F	protein	taxon:9606	20120508	MGI		UniProtKB:Q6ZSY5
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q7Z4G1	COMMD6	acts_upstream_of_or_within	GO:0032088	PMID:16573520	IDA		P	COMM domain-containing protein 6	COMMD6|MSTP076	protein	taxon:9606	20120309	MGI		UniProtKB:Q7Z4G1
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q8IZP0	ABI1	acts_upstream_of_or_within	GO:0061098	PMID:17101133	IDA		P	Abl interactor 1	ABI1|SSH3BP1	protein	taxon:9606	20220830	MGI		UniProtKB:Q8IZP0
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q8N668	COMMD1	acts_upstream_of_or_within	GO:0032088	PMID:16573520	IDA		P	COMM domain-containing protein 1	COMMD1|C2orf5|MURR1	protein	taxon:9606	20120309	MGI		UniProtKB:Q8N668
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q8NCT1	ARRDC4	acts_upstream_of_or_within	GO:0051443	PMID:23236378	IPI	UniProtKB:Q96PU5	P	Arrestin domain-containing protein 4	ARRDC4	protein	taxon:9606	20130829	MGI		UniProtKB:Q8NCT1
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q8NEB9	PIK3C3	acts_upstream_of_or_within	GO:1903061	PMID:25327288	IMP		P	Phosphatidylinositol 3-kinase catalytic subunit type 3	PIK3C3|VPS34	protein	taxon:9606	20241002	MGI	has_input(UniProtKB:Q9H492)	UniProtKB:Q8NEB9
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q8NFZ0	FBH1	acts_upstream_of_or_within	GO:0001934	PMID:23361013	IMP		P	F-box DNA helicase 1	FBH1|FBX18|FBXO18	protein	taxon:9606	20140627	MGI		UniProtKB:Q8NFZ0
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q8TDC3	BRSK1	acts_upstream_of_or_within	GO:0018105	PMID:15150265	IDA		P	Serine/threonine-protein kinase BRSK1	BRSK1|KIAA1811|SAD1|SADB	protein	taxon:9606	20191113	MGI		UniProtKB:Q8TDC3
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q969G6	RFK	acts_upstream_of_or_within	GO:0033864	PMID:19641494	IMP		P	Riboflavin kinase	RFK	protein	taxon:9606	20131209	MGI		UniProtKB:Q969G6
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q96B67	ARRDC3	acts_upstream_of_or_within	GO:0051443	PMID:23236378	IPI	UniProtKB:Q96PU5	P	Arrestin domain-containing protein 3	ARRDC3|KIAA1376	protein	taxon:9606	20130829	MGI		UniProtKB:Q96B67
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q96BJ3	AIDA	acts_upstream_of_or_within	GO:0043508	PMID:17681137	IDA		P	Axin interactor, dorsalization-associated protein	AIDA|C1orf80	protein	taxon:9606	20110406	MGI		UniProtKB:Q96BJ3
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q96L73	NSD1	acts_upstream_of_or_within	GO:0033135	PMID:20837538	IMP		P	Histone-lysine N-methyltransferase, H3 lysine-36 specific	NSD1|ARA267|KMT3B	protein	taxon:9606	20150406	MGI		UniProtKB:Q96L73
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q99490	AGAP2	acts_upstream_of_or_within	GO:0045860	PMID:14761976	IDA		P	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2	AGAP2|CENTG1|KIAA0167	protein	taxon:9606	20191112	MGI		UniProtKB:Q99490
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q99759	MAP3K3	acts_upstream_of_or_within	GO:0046777	PMID:15001576	IDA		P	Mitogen-activated protein kinase kinase kinase 3	MAP3K3|MAPKKK3|MEKK3	protein	taxon:9606	20060120	MGI		UniProtKB:Q99759
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9BUP3	HTATIP2	acts_upstream_of_or_within	GO:0046777	PMID:10698937	IDA		P	Oxidoreductase HTATIP2	HTATIP2|CC3|TIP30	protein	taxon:9606	20191115	MGI		UniProtKB:Q9BUP3
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9C0B5	ZDHHC5	acts_upstream_of_or_within	GO:0018345	PMID:22325201	IDA		P	Palmitoyltransferase ZDHHC5	ZDHHC5|KIAA1748|ZNF375	protein	taxon:9606	20121130	MGI		UniProtKB:Q9C0B5
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9H267	VPS33B	acts_upstream_of_or_within	GO:0017185	PMID:27435297	IMP		P	Vacuolar protein sorting-associated protein 33B	VPS33B	protein	taxon:9606	20170517	MGI		UniProtKB:Q9H267
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9H2J4	PDCL3	acts_upstream_of_or_within	GO:0050730	PMID:23792958	IMP		P	Phosducin-like protein 3	PDCL3|PhLP2A|VIAF1	protein	taxon:9606	20140115	MGI		UniProtKB:Q9H2J4
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9H4Q4	PRDM12	acts_upstream_of_or_within	GO:0006479	PMID:26005867	IDA		P	PR domain zinc finger protein 12	PRDM12|PFM9	protein	taxon:9606	20220922	MGI		UniProtKB:Q9H4Q4
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9H8T0	AKTIP	acts_upstream_of_or_within	GO:0001934	PMID:14749367	IDA		P	AKT-interacting protein	AKTIP|FTS	protein	taxon:9606	20091109	MGI		UniProtKB:Q9H8T0
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9H9C1	VIPAS39	acts_upstream_of_or_within	GO:0017185	PMID:27435297	IMP		P	Spermatogenesis-defective protein 39 homolog	VIPAS39|C14orf133|SPE39|VIPAR	protein	taxon:9606	20170517	MGI		UniProtKB:Q9H9C1
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9HAT8	PELI2	acts_upstream_of_or_within	GO:0001934	PMID:12804775	IDA		P	E3 ubiquitin-protein ligase pellino homolog 2	PELI2	protein	taxon:9606	20110202	MGI		UniProtKB:Q9HAT8
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9HBE4	IL21	acts_upstream_of_or_within	GO:0042531	PMID:17673207	IDA		P	Interleukin-21	IL21	protein	taxon:9606	20170417	MGI		UniProtKB:Q9HBE4
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9HC29	NOD2	acts_upstream_of_or_within	GO:0051092	PMID:12527755	IDA		P	Nucleotide-binding oligomerization domain-containing protein 2	NOD2|CARD15	protein	taxon:9606	20101104	MGI		UniProtKB:Q9HC29
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9NQZ6	ZC4H2	acts_upstream_of_or_within	GO:0051091	PMID:32094113	IGI	UniProtKB:Q5VTB9	P	Zinc finger C4H2 domain-containing protein	ZC4H2|HCA127|KIAA1166	protein	taxon:9606	20210805	MGI		UniProtKB:Q9NQZ6
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9NX18	SDHAF2	acts_upstream_of_or_within	GO:0006470	PMID:23983127	IGI	UniProtKB:P67775	P	Succinate dehydrogenase assembly factor 2, mitochondrial	SDHAF2|C11orf79|PGL2|SDH5	protein	taxon:9606	20140620	MGI		UniProtKB:Q9NX18
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9NYB9	ABI2	acts_upstream_of_or_within	GO:0018108	PMID:17101133	IDA		P	Abl interactor 2	ABI2|ARGBPIA	protein	taxon:9606	20070711	MGI		UniProtKB:Q9NYB9
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9NZN9	AIPL1	acts_upstream_of_or_within	GO:0018343	PMID:14555765	IDA		P	Aryl-hydrocarbon-interacting protein-like 1	AIPL1|AIPL2	protein	taxon:9606	20101102	MGI		UniProtKB:Q9NZN9
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9P287	BCCIP	acts_upstream_of_or_within	GO:0000079	PMID:10878006	IDA		P	BRCA2 and CDKN1A-interacting protein	BCCIP|TOK1	protein	taxon:9606	20091019	MGI		UniProtKB:Q9P287
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9P2A4	ABI3	NOT|acts_upstream_of_or_within	GO:0018108	PMID:17101133	IDA		P	ABI gene family member 3	ABI3|NESH	protein	taxon:9606	20070711	MGI		UniProtKB:Q9P2A4
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9P2B4	CTTNBP2NL	acts_upstream_of_or_within	GO:0006470	PMID:24218568	IMP		P	CTTNBP2 N-terminal-like protein	CTTNBP2NL|KIAA1433	protein	taxon:9606	20140606	MGI		UniProtKB:Q9P2B4
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9P2B4	CTTNBP2NL	acts_upstream_of_or_within	GO:0032410	PMID:24218568	IMP		P	CTTNBP2 N-terminal-like protein	CTTNBP2NL|KIAA1433	protein	taxon:9606	20140609	MGI		UniProtKB:Q9P2B4
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9P2D0	IBTK	acts_upstream_of_or_within	GO:0001933	PMID:11577348	IDA		P	Inhibitor of Bruton tyrosine kinase	IBTK|BTKI|KIAA1417	protein	taxon:9606	20090324	MGI		UniProtKB:Q9P2D0
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9UIC8	LCMT1	acts_upstream_of_or_within	GO:0006479	PMID:17724024	IMP		P	Leucine carboxyl methyltransferase 1	LCMT1|LCMT|CGI-68	protein	taxon:9606	20130311	MGI		UniProtKB:Q9UIC8
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9UIC8	LCMT1	acts_upstream_of_or_within	GO:0006481	PMID:10600115	IDA		P	Leucine carboxyl methyltransferase 1	LCMT1|LCMT|CGI-68	protein	taxon:9606	20011206	MGI		UniProtKB:Q9UIC8
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9UM73	ALK	acts_upstream_of_or_within	GO:0046777	PMID:9174053	IDA		P	ALK tyrosine kinase receptor	ALK	protein	taxon:9606	20130916	MGI		UniProtKB:Q9UM73
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9Y210	TRPC6	acts_upstream_of_or_within	GO:0032414	PMID:10998353	IDA		P	Short transient receptor potential channel 6	TRPC6|TRP6	protein	taxon:9606	20110114	MGI		UniProtKB:Q9Y210
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9Y2C9	TLR6	acts_upstream_of_or_within	GO:0043507	PMID:10231569	IDA		P	Toll-like receptor 6	TLR6	protein	taxon:9606	20070628	MGI		UniProtKB:Q9Y2C9
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9Y2H1	STK38L	acts_upstream_of_or_within	GO:0006468	PMID:15037617	IDA		P	Serine/threonine-protein kinase 38-like	STK38L|KIAA0965|NDR2	protein	taxon:9606	20110329	MGI		UniProtKB:Q9Y2H1
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P56965	DDAH1	acts_upstream_of_or_within	GO:0017014	PMID:12441345	IDA		P	N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	DDAH1	protein	taxon:9913	20030403	MGI		UniProtKB:P56965
`