# Group: paint - Dataset: paint_goa_human

## SUMMARY

This report generated on 2024-12-19

  * Associations: 64056
  * Lines in file (incl headers): 64116
  * Lines skipped: 54
## Header From Original Association File

> !gaf-version: 2.2  
> !Created on Thu Nov 21 14:20:14 2024.  
> !generated-by: PANTHER  
> !date-generated: 2024-11-21  
> !PANTHER version: v.19.0.  
> !GO version: 2024-11-03.  

## Contents

[gorule-0000002](#gorule-0000002)

[gorule-0000005](#gorule-0000005)

[gorule-0000006](#gorule-0000006)

[gorule-0000007](#gorule-0000007)

[gorule-0000008](#gorule-0000008)

[gorule-0000011](#gorule-0000011)

[gorule-0000013](#gorule-0000013)

[gorule-0000015](#gorule-0000015)

[gorule-0000016](#gorule-0000016)

[gorule-0000017](#gorule-0000017)

[gorule-0000018](#gorule-0000018)

[gorule-0000020](#gorule-0000020)

[gorule-0000022](#gorule-0000022)

[gorule-0000027](#gorule-0000027)

[gorule-0000028](#gorule-0000028)

[gorule-0000029](#gorule-0000029)

[gorule-0000030](#gorule-0000030)

[gorule-0000037](#gorule-0000037)

[gorule-0000039](#gorule-0000039)

[gorule-0000042](#gorule-0000042)

[gorule-0000043](#gorule-0000043)

[gorule-0000046](#gorule-0000046)

[gorule-0000050](#gorule-0000050)

[gorule-0000055](#gorule-0000055)

[gorule-0000058](#gorule-0000058)

[gorule-0000061](#gorule-0000061)

[gorule-0000063](#gorule-0000063)

[gorule-0000064](#gorule-0000064)

[gorule-0000065](#gorule-0000065)

[other](#other)


## MESSAGES

### gorule-0000002

No 'NOT' annotations to binding ; GO:0005488 or 'protein binding ; GO:0005515'

* total: 0
### gorule-0000005

IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to to 'protein binding ; GO:0005515 or GO:0005488 binding''

* total: 0
### gorule-0000006

IEP and HEP usage is restricted to terms from the Biological Process ontology, except when assigned by GOC

* total: 0
### gorule-0000007

IPI should not be used with GO:0003824 catalytic activity or descendents

* total: 0
### gorule-0000008

No annotations should be made to uninformative high level terms

* total: 0
### gorule-0000011

ND evidence code should be to root nodes only, and no terms other than root nodes can have the evidence code ND

* total: 0
### gorule-0000013

Taxon-appropriate annotation check

* total: 14
#### Messages
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	P27448	MARK3	enables	GO:0050321	GO_REF:0000033	IBA	PANTHER:PTN000680111|UniProtKB:P27448|FB:FBgn0260934|UniProtKB:Q7KZI7|RGD:708483|UniProtKB:Q96L34	F	MAP_microtubule affinity-regulating kinase 3	UniProtKB:P27448|PTN002519173	protein	taxon:9606	20200809	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	Q8TDC3	BRSK1	enables	GO:0050321	GO_REF:0000033	IBA	PANTHER:PTN000679673|MGI:MGI:2685946|UniProtKB:Q8TDC3|MGI:MGI:1923020|UniProtKB:Q8IWQ3	F	Serine_threonine-protein kinase BRSK1	UniProtKB:Q8TDC3|PTN002519147	protein	taxon:9606	20230603	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	P21695	GPD1	enables	GO:0047952	GO_REF:0000033	IBA	PANTHER:PTN000919759|MGI:MGI:95679|UniProtKB:C8VTT9|SGD:S000005420|SGD:S000002180	F	Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic	UniProtKB:P21695|PTN002482427	protein	taxon:9606	20241120	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	Q7Z6K4	NRARP	is_active_in	GO:0009707	GO_REF:0000033	IBA	PANTHER:PTN002794166|TAIR:locus:2117607	C	Notch-regulated ankyrin repeat-containing protein	UniProtKB:Q7Z6K4|PTN002516782	protein	taxon:9606	20240206	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	Q9P2S5	WRAP73	involved_in	GO:1990810	GO_REF:0000033	IBA	PANTHER:PTN000416664|PomBase:SPBC32H8.09	P	WD repeat-containing protein WRAP73	UniProtKB:Q9P2S5|PTN002497254	protein	taxon:9606	20200319	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	P49841	GSK3B	enables	GO:0050321	GO_REF:0000033	IBA	PANTHER:PTN002780427|RGD:70982|MGI:MGI:1861437|UniProtKB:P49841	F	Glycogen synthase kinase-3 beta	UniProtKB:P49841|PTN002514197	protein	taxon:9606	20190426	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	Q8IWQ3	BRSK2	enables	GO:0050321	GO_REF:0000033	IBA	PANTHER:PTN000679673|MGI:MGI:2685946|UniProtKB:Q8TDC3|MGI:MGI:1923020|UniProtKB:Q8IWQ3	F	Serine_threonine-protein kinase BRSK2	UniProtKB:Q8IWQ3|PTN002519146	protein	taxon:9606	20230603	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	Q96L34	MARK4	enables	GO:0050321	GO_REF:0000033	IBA	PANTHER:PTN000680111|UniProtKB:P27448|FB:FBgn0260934|UniProtKB:Q7KZI7|RGD:708483|UniProtKB:Q96L34	F	MAP_microtubule affinity-regulating kinase 4	UniProtKB:Q96L34|PTN002519163	protein	taxon:9606	20200809	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	Q9Y2G4	ANKRD6	is_active_in	GO:0009707	GO_REF:0000033	IBA	PANTHER:PTN002794166|TAIR:locus:2117607	C	Ankyrin repeat domain-containing protein 6	UniProtKB:Q9Y2G4|PTN002516781	protein	taxon:9606	20240206	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	Q9Y2K2	SIK3	enables	GO:0050321	GO_REF:0000033	IBA	PANTHER:PTN000680111|UniProtKB:P27448|FB:FBgn0260934|UniProtKB:Q7KZI7|RGD:708483|UniProtKB:Q96L34	F	Serine_threonine-protein kinase SIK3	UniProtKB:Q9Y2K2|PTN002506480	protein	taxon:9606	20200809	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	Q9NXR5	ANKRD10	is_active_in	GO:0009707	GO_REF:0000033	IBA	PANTHER:PTN002794166|TAIR:locus:2117607	C	Ankyrin repeat domain-containing protein 10	UniProtKB:Q9NXR5|PTN002516779	protein	taxon:9606	20240206	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	Q15493	RGN	involved_in	GO:0019853	GO_REF:0000033	IBA	PANTHER:PTN000097355|MGI:MGI:108024	P	Regucalcin	UniProtKB:Q15493|PTN002474931	protein	taxon:9606	20170228	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	Q86W50	METTL16	enables	GO:0052907	GO_REF:0000033	IBA	PANTHER:PTN000333539|UniProtKB:P75782	F	RNA N6-adenosine-methyltransferase METTL16	UniProtKB:Q86W50|PTN002491541	protein	taxon:9606	20170228	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	Q7KZI7	MARK2	enables	GO:0050321	GO_REF:0000033	IBA	PANTHER:PTN000680111|UniProtKB:P27448|FB:FBgn0260934|UniProtKB:Q7KZI7|RGD:708483|UniProtKB:Q96L34	F	Serine_threonine-protein kinase MARK2	UniProtKB:Q7KZI7|PTN002519164	protein	taxon:9606	20200809	GO_Central		
`
### gorule-0000015

Dual species taxon check

* total: 0
### gorule-0000016

With/From: IC annotations require a With/From GO ID

* total: 0
### gorule-0000017

IDA annotations must not have a With/From entry

* total: 0
### gorule-0000018

IPI annotations require a With/From entry

* total: 0
### gorule-0000020

Automatic repair of annotations to merged or obsoleted terms

* total: 66
#### Messages
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0006266) -- `UniProtKB	P18858	LIG1	involved_in	GO:0006266	GO_REF:0000033	IBA	PANTHER:PTN000048696|RGD:1309875|SGD:S000002323|UniProtKB:P49916	P	DNA ligase 1	UniProtKB:P18858|PTN002470869	protein	taxon:9606	20241121	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0006288) -- `UniProtKB	P49916	LIG3	involved_in	GO:0006288	GO_REF:0000033	IBA	PANTHER:PTN000825510|UniProtKB:P49916|RGD:1309875	P	DNA ligase 3	UniProtKB:P49916|PTN002470844	protein	taxon:9606	20220517	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0032508) -- `UniProtKB	A8MPP1	DDX11L8	involved_in	GO:0032508	GO_REF:0000033	IBA	PANTHER:PTN000158371|UniProtKB:Q96FC9	P	Putative ATP-dependent RNA helicase DDX11-like protein 8	UniProtKB:A8MPP1|PTN002479322	protein	taxon:9606	20200929	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0032508) -- `UniProtKB	Q92771	DDX12P	involved_in	GO:0032508	GO_REF:0000033	IBA	PANTHER:PTN000158371|UniProtKB:Q96FC9	P	Putative ATP-dependent RNA helicase DDX12	UniProtKB:Q92771|PTN002479321	protein	taxon:9606	20200929	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0032508) -- `UniProtKB	Q96FC9	DDX11	involved_in	GO:0032508	GO_REF:0000033	IBA	PANTHER:PTN000158371|UniProtKB:Q96FC9	P	ATP-dependent DNA helicase DDX11	UniProtKB:Q96FC9|PTN002479319	protein	taxon:9606	20200929	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0032508) -- `UniProtKB	Q92878	RAD50	involved_in	GO:0032508	GO_REF:0000033	IBA	PANTHER:PTN000429848|UniProtKB:Q92878	P	DNA repair protein RAD50	UniProtKB:Q92878|PTN002497981	protein	taxon:9606	20170228	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0032508) -- `UniProtKB	O60934	NBN	involved_in	GO:0032508	GO_REF:0000033	IBA	PANTHER:PTN000255549|UniProtKB:O60934	P	Nibrin	UniProtKB:O60934|PTN002486512	protein	taxon:9606	20170228	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0032508) -- `UniProtKB	Q9NZ71	RTEL1	involved_in	GO:0032508	GO_REF:0000033	IBA	PANTHER:PTN000158195|MGI:MGI:2139369	P	Regulator of telomere elongation helicase 1	UniProtKB:Q9NZ71|PTN002479334	protein	taxon:9606	20200929	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0042989) -- `UniProtKB	Q6IBS0	TWF2	involved_in	GO:0042989	GO_REF:0000033	IBA	PANTHER:PTN001011683|SGD:S000003312|MGI:MGI:1346078|MGI:MGI:1100520	P	Twinfilin-2	UniProtKB:Q6IBS0|PTN002492612	protein	taxon:9606	20170421	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0042989) -- `UniProtKB	A0A087X1C1	TMSB15B	involved_in	GO:0042989	GO_REF:0000033	IBA	PANTHER:PTN002280337|MGI:MGI:3843061|UniProtKB:P62328|UniProtKB:P62326	P	Thymosin beta 15B	UniProtKB:A0A087X1C1|PTN002634970	protein	taxon:9606	20221007	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0042989) -- `UniProtKB	P62328	TMSB4X	involved_in	GO:0042989	GO_REF:0000033	IBA	PANTHER:PTN002280337|MGI:MGI:3843061|UniProtKB:P62328|UniProtKB:P62326	P	Thymosin beta-4	UniProtKB:P62328|PTN002485910	protein	taxon:9606	20221007	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0042989) -- `UniProtKB	P0CG35	TMSB15B	involved_in	GO:0042989	GO_REF:0000033	IBA	PANTHER:PTN002280337|MGI:MGI:3843061|UniProtKB:P62328|UniProtKB:P62326	P	Thymosin beta-15B	UniProtKB:P0CG35|PTN002485908	protein	taxon:9606	20221007	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0042989) -- `UniProtKB	P0CG34	TMSB15A	involved_in	GO:0042989	GO_REF:0000033	IBA	PANTHER:PTN002280337|MGI:MGI:3843061|UniProtKB:P62328|UniProtKB:P62326	P	Thymosin beta-15A	UniProtKB:P0CG34|PTN002485907	protein	taxon:9606	20221007	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0042989) -- `UniProtKB	O14604	TMSB4Y	involved_in	GO:0042989	GO_REF:0000033	IBA	PANTHER:PTN002280337|MGI:MGI:3843061|UniProtKB:P62328|UniProtKB:P62326	P	Thymosin beta-4, Y-chromosomal	UniProtKB:O14604|PTN002485909	protein	taxon:9606	20221007	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0042989) -- `UniProtKB	Q12792	TWF1	involved_in	GO:0042989	GO_REF:0000033	IBA	PANTHER:PTN001011683|SGD:S000003312|MGI:MGI:1346078|MGI:MGI:1100520	P	Twinfilin-1	UniProtKB:Q12792|PTN002492611	protein	taxon:9606	20170421	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0042989) -- `UniProtKB	P63313	TMSB10	involved_in	GO:0042989	GO_REF:0000033	IBA	PANTHER:PTN002280337|MGI:MGI:3843061|UniProtKB:P62328|UniProtKB:P62326	P	Thymosin beta-10	UniProtKB:P63313|PTN002485911	protein	taxon:9606	20221007	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0042989) -- `UniProtKB	Q8NHR9	PFN4	involved_in	GO:0042989	GO_REF:0000033	IBA	PANTHER:PTN000176159|SGD:S000005648|UniProtKB:P35081|UniProtKB:O22655|UniProtKB:Q8I2J4|UniProtKB:Q9FR39	P	Profilin-4	UniProtKB:Q8NHR9|PTN002480854	protein	taxon:9606	20230110	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0044806) -- `UniProtKB	Q14191	WRN	involved_in	GO:0044806	GO_REF:0000033	IBA	PANTHER:PTN002492232|UniProtKB:Q14191|MGI:MGI:109635	P	Bifunctional 3'-5' exonuclease_ATP-dependent helicase WRN	UniProtKB:Q14191|PTN002492235	protein	taxon:9606	20190113	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0044806) -- `UniProtKB	P54132	BLM	involved_in	GO:0044806	GO_REF:0000033	IBA	PANTHER:PTN002672422|MGI:MGI:1328362|UniProtKB:P54132	P	RecQ-like DNA helicase BLM	UniProtKB:P54132|PTN002492240	protein	taxon:9606	20190319	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0051103) -- `UniProtKB	Q13426	XRCC4	involved_in	GO:0051103	GO_REF:0000033	IBA	PANTHER:PTN002004633|UniProtKB:Q13426	P	DNA repair protein XRCC4	UniProtKB:Q13426|PTN002523890	protein	taxon:9606	20190520	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0051220) -- `UniProtKB	Q16643	DBN1	involved_in	GO:0051220	GO_REF:0000033	IBA	PANTHER:PTN002866991|UniProtKB:Q16643	P	Drebrin	UniProtKB:Q16643|PTN002474320	protein	taxon:9606	20230720	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0052695) -- `UniProtKB	P36537	UGT2B10	involved_in	GO:0052695	GO_REF:0000033	IBA	PANTHER:PTN002484653|UniProtKB:O75310|UniProtKB:P06133|UniProtKB:Q9BY64|UniProtKB:P16662	P	UDP-glucuronosyltransferase 2B10	UniProtKB:P36537|PTN002484655	protein	taxon:9606	20221010	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0052695) -- `UniProtKB	Q9HAW7	UGT1A7	involved_in	GO:0052695	GO_REF:0000033	IBA	PANTHER:PTN002630028|UniProtKB:P19224|UniProtKB:O60656|UniProtKB:P35503|UniProtKB:Q9HAW9|UniProtKB:P22310|UniProtKB:Q9HAW8|RGD:3935|UniProtKB:P22309|UniProtKB:Q9HAW7	P	UDP-glucuronosyltransferase 1A7	UniProtKB:Q9HAW7|PTN002484638	protein	taxon:9606	20241121	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0052695) -- `UniProtKB	O75310	UGT2B11	involved_in	GO:0052695	GO_REF:0000033	IBA	PANTHER:PTN002484653|UniProtKB:O75310|UniProtKB:P06133|UniProtKB:Q9BY64|UniProtKB:P16662	P	UDP-glucuronosyltransferase 2B11	UniProtKB:O75310|PTN002484660	protein	taxon:9606	20221010	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0052695) -- `UniProtKB	P22310	UGT1A4	involved_in	GO:0052695	GO_REF:0000033	IBA	PANTHER:PTN002630028|UniProtKB:P19224|UniProtKB:O60656|UniProtKB:P35503|UniProtKB:Q9HAW9|UniProtKB:P22310|UniProtKB:Q9HAW8|RGD:3935|UniProtKB:P22309|UniProtKB:Q9HAW7	P	UDP-glucuronosyltransferase 1A4	UniProtKB:P22310|PTN002484647	protein	taxon:9606	20241121	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0052695) -- `UniProtKB	Q9BY64	UGT2B28	involved_in	GO:0052695	GO_REF:0000033	IBA	PANTHER:PTN002484653|UniProtKB:O75310|UniProtKB:P06133|UniProtKB:Q9BY64|UniProtKB:P16662	P	UDP-glucuronosyltransferase 2B28	UniProtKB:Q9BY64|PTN002484659	protein	taxon:9606	20221010	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0052695) -- `UniProtKB	P0DTE4	UGT2A1	involved_in	GO:0052695	GO_REF:0000033	IBA	PANTHER:PTN000938772|UniProtKB:P0DTE4	P	UDP-glucuronosyltransferase 2A1	UniProtKB:P0DTE4|PTN002484678	protein	taxon:9606	20220121	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0052695) -- `UniProtKB	P16662	UGT2B7	involved_in	GO:0052695	GO_REF:0000033	IBA	PANTHER:PTN002484653|UniProtKB:O75310|UniProtKB:P06133|UniProtKB:Q9BY64|UniProtKB:P16662	P	UDP-glucuronosyltransferase 2B7	UniProtKB:P16662|PTN002484661	protein	taxon:9606	20221010	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0052695) -- `UniProtKB	P35504	UGT1A5	involved_in	GO:0052695	GO_REF:0000033	IBA	PANTHER:PTN002630028|UniProtKB:P19224|UniProtKB:O60656|UniProtKB:P35503|UniProtKB:Q9HAW9|UniProtKB:P22310|UniProtKB:Q9HAW8|RGD:3935|UniProtKB:P22309|UniProtKB:Q9HAW7	P	UDP-glucuronosyltransferase 1A5	UniProtKB:P35504|PTN002484648	protein	taxon:9606	20241121	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0052695) -- `UniProtKB	P06133	UGT2B4	involved_in	GO:0052695	GO_REF:0000033	IBA	PANTHER:PTN002484653|UniProtKB:O75310|UniProtKB:P06133|UniProtKB:Q9BY64|UniProtKB:P16662	P	UDP-glucuronosyltransferase 2B4	UniProtKB:P06133|PTN002484662	protein	taxon:9606	20221010	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0052695) -- `UniProtKB	O60656	UGT1A9	involved_in	GO:0052695	GO_REF:0000033	IBA	PANTHER:PTN002630028|UniProtKB:P19224|UniProtKB:O60656|UniProtKB:P35503|UniProtKB:Q9HAW9|UniProtKB:P22310|UniProtKB:Q9HAW8|RGD:3935|UniProtKB:P22309|UniProtKB:Q9HAW7	P	UDP-glucuronosyltransferase 1A9	UniProtKB:O60656|PTN002484636	protein	taxon:9606	20241121	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0052695) -- `UniProtKB	Q9HAW9	UGT1A8	involved_in	GO:0052695	GO_REF:0000033	IBA	PANTHER:PTN002630028|UniProtKB:P19224|UniProtKB:O60656|UniProtKB:P35503|UniProtKB:Q9HAW9|UniProtKB:P22310|UniProtKB:Q9HAW8|RGD:3935|UniProtKB:P22309|UniProtKB:Q9HAW7	P	UDP-glucuronosyltransferase 1A8	UniProtKB:Q9HAW9|PTN002484639	protein	taxon:9606	20241121	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0052695) -- `UniProtKB	Q6UWM9	UGT2A3	involved_in	GO:0052695	GO_REF:0000033	IBA	PANTHER:PTN000230675|UniProtKB:Q6UWM9	P	UDP-glucuronosyltransferase 2A3	UniProtKB:Q6UWM9|PTN002484674	protein	taxon:9606	20221010	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0052695) -- `UniProtKB	P19224	UGT1A6	involved_in	GO:0052695	GO_REF:0000033	IBA	PANTHER:PTN002630028|UniProtKB:P19224|UniProtKB:O60656|UniProtKB:P35503|UniProtKB:Q9HAW9|UniProtKB:P22310|UniProtKB:Q9HAW8|RGD:3935|UniProtKB:P22309|UniProtKB:Q9HAW7	P	UDP-glucuronosyltransferase 1-6	UniProtKB:P19224|PTN002484637	protein	taxon:9606	20241121	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0052695) -- `UniProtKB	P22309	UGT1A1	involved_in	GO:0052695	GO_REF:0000033	IBA	PANTHER:PTN002630028|UniProtKB:P19224|UniProtKB:O60656|UniProtKB:P35503|UniProtKB:Q9HAW9|UniProtKB:P22310|UniProtKB:Q9HAW8|RGD:3935|UniProtKB:P22309|UniProtKB:Q9HAW7	P	UDP-glucuronosyltransferase 1A1	UniProtKB:P22309|PTN002484643	protein	taxon:9606	20241121	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0052695) -- `UniProtKB	Q9HAW8	UGT1A10	involved_in	GO:0052695	GO_REF:0000033	IBA	PANTHER:PTN002630028|UniProtKB:P19224|UniProtKB:O60656|UniProtKB:P35503|UniProtKB:Q9HAW9|UniProtKB:P22310|UniProtKB:Q9HAW8|RGD:3935|UniProtKB:P22309|UniProtKB:Q9HAW7	P	UDP-glucuronosyltransferase 1A10	UniProtKB:Q9HAW8|PTN002484640	protein	taxon:9606	20241121	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0052695) -- `UniProtKB	O75795	UGT2B17	involved_in	GO:0052695	GO_REF:0000033	IBA	PANTHER:PTN000230597|UniProtKB:O75795|UniProtKB:P54855	P	UDP-glucuronosyltransferase 2B17	UniProtKB:O75795|PTN002484663	protein	taxon:9606	20221010	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0052695) -- `UniProtKB	P35503	UGT1A3	involved_in	GO:0052695	GO_REF:0000033	IBA	PANTHER:PTN002630028|UniProtKB:P19224|UniProtKB:O60656|UniProtKB:P35503|UniProtKB:Q9HAW9|UniProtKB:P22310|UniProtKB:Q9HAW8|RGD:3935|UniProtKB:P22309|UniProtKB:Q9HAW7	P	UDP-glucuronosyltransferase 1A3	UniProtKB:P35503|PTN002484646	protein	taxon:9606	20241121	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0052695) -- `UniProtKB	P54855	UGT2B15	involved_in	GO:0052695	GO_REF:0000033	IBA	PANTHER:PTN000230597|UniProtKB:O75795|UniProtKB:P54855	P	UDP-glucuronosyltransferase 2B15	UniProtKB:P54855|PTN002484664	protein	taxon:9606	20221010	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0070643) -- `UniProtKB	Q07973	CYP24A1	enables	GO:0070643	GO_REF:0000033	IBA	PANTHER:PTN002801018|RGD:2462|UniProtKB:Q07973	F	1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	UniProtKB:Q07973|PTN002518061	protein	taxon:9606	20200206	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `UniProtKB	O94761	RECQL4	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000344874|SGD:S000004802	P	ATP-dependent DNA helicase Q4	UniProtKB:O94761|PTN002492211	protein	taxon:9606	20190319	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `UniProtKB	Q04837	SSBP1	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000033807|FB:FBgn0010438|UniProtKB:Q04837	P	Single-stranded DNA-binding protein, mitochondrial	UniProtKB:Q04837|PTN002469826	protein	taxon:9606	20240820	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `UniProtKB	P49736	MCM2	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000179907|UniProtKB:Q2R482|MGI:MGI:105380|UniProtKB:P49736	P	DNA replication licensing factor MCM2	UniProtKB:P49736|PTN002481144	protein	taxon:9606	20211215	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `UniProtKB	P33991	MCM4	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000179968|SGD:S000006223|UniProtKB:P33991|MGI:MGI:103199	P	DNA replication licensing factor MCM4	UniProtKB:P33991|PTN002481158	protein	taxon:9606	20211215	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `UniProtKB	Q14566	MCM6	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000180096|MGI:MGI:1298227|UniProtKB:Q14566|SGD:S000003169	P	DNA replication licensing factor MCM6	UniProtKB:Q14566|PTN002481146	protein	taxon:9606	20211215	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `UniProtKB	P54132	BLM	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000344874|SGD:S000004802	P	RecQ-like DNA helicase BLM	UniProtKB:P54132|PTN002492240	protein	taxon:9606	20190319	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `UniProtKB	P46063	RECQL	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000344874|SGD:S000004802	P	ATP-dependent DNA helicase Q1	UniProtKB:P46063|PTN002492223	protein	taxon:9606	20190319	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `UniProtKB	Q14191	WRN	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000344874|SGD:S000004802	P	Bifunctional 3'-5' exonuclease_ATP-dependent helicase WRN	UniProtKB:Q14191|PTN002492235	protein	taxon:9606	20190319	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `UniProtKB	P27694	RPA1	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000588618|SGD:S000000065	P	Replication protein A 70 kDa DNA-binding subunit	UniProtKB:P27694|PTN002510702	protein	taxon:9606	20210531	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `UniProtKB	P33993	MCM7	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000180038|MGI:MGI:1298398|UniProtKB:P33993|SGD:S000000406	P	DNA replication licensing factor MCM7	UniProtKB:P33993|PTN002481149	protein	taxon:9606	20211215	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `UniProtKB	O94762	RECQL5	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000344874|SGD:S000004802	P	ATP-dependent DNA helicase Q5	UniProtKB:O94762|PTN002492237	protein	taxon:9606	20190319	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006977) -- `UniProtKB	P78560	CRADD	involved_in	GO:0006977	GO_REF:0000033	IBA	PANTHER:PTN008354075|UniProtKB:P78560	P	Death domain-containing protein CRADD	UniProtKB:P78560|PTN002495384	protein	taxon:9606	20240924	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006978) -- `UniProtKB	Q9UK32	RPS6KA6	involved_in	GO:0006978	GO_REF:0000033	IBA	PANTHER:PTN002806567|UniProtKB:Q9UK32	P	Ribosomal protein S6 kinase alpha-6	UniProtKB:Q9UK32|PTN002519333	protein	taxon:9606	20200917	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	Q9HD15	SRA1	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN001050482|RGD:621148	F	Steroid receptor RNA activator 1	UniProtKB:Q9HD15|PTN002497917	protein	taxon:9606	20241120	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	Q15596	NCOA2	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000074430|UniProtKB:Q15788|RGD:620109|FB:FBgn0041092|MGI:MGI:1276535|UniProtKB:Q9Y6Q9|UniProtKB:Q15596|MGI:MGI:1276533	F	Nuclear receptor coactivator 2	UniProtKB:Q15596|PTN002473106	protein	taxon:9606	20241119	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	Q8NF64	ZMIZ2	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000081664|UniProtKB:Q8NF64	F	Zinc finger MIZ domain-containing protein 2	UniProtKB:Q8NF64|PTN002473585	protein	taxon:9606	20190426	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	Q9Y6Q9	NCOA3	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000074430|UniProtKB:Q15788|RGD:620109|FB:FBgn0041092|MGI:MGI:1276535|UniProtKB:Q9Y6Q9|UniProtKB:Q15596|MGI:MGI:1276533	F	Nuclear receptor coactivator 3	UniProtKB:Q9Y6Q9|PTN002473103	protein	taxon:9606	20241119	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	Q58WW2	DCAF6	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000400123|UniProtKB:Q58WW2	F	DDB1- and CUL4-associated factor 6	UniProtKB:Q58WW2|PTN002496245	protein	taxon:9606	20190726	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	Q15788	NCOA1	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000074430|UniProtKB:Q15788|RGD:620109|FB:FBgn0041092|MGI:MGI:1276535|UniProtKB:Q9Y6Q9|UniProtKB:Q15596|MGI:MGI:1276533	F	Nuclear receptor coactivator 1	UniProtKB:Q15788|PTN002473105	protein	taxon:9606	20241119	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	Q86XK3	SFR1	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN002008993|UniProtKB:Q86XK3	F	Swi5-dependent recombination DNA repair protein 1 homolog	UniProtKB:Q86XK3|PTN002524030	protein	taxon:9606	20171117	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	Q5VV67	PPRC1	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000399017|UniProtKB:Q86YN6|UniProtKB:Q9UBK2	F	Peroxisome proliferator-activated receptor gamma coactivator-related protein 1	UniProtKB:Q5VV67|PTN002496180	protein	taxon:9606	20170228	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	Q86YN6	PPARGC1B	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000399017|UniProtKB:Q86YN6|UniProtKB:Q9UBK2	F	Peroxisome proliferator-activated receptor gamma coactivator 1-beta	UniProtKB:Q86YN6|PTN002496177	protein	taxon:9606	20170228	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	Q9UBK2	PPARGC1A	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000399017|UniProtKB:Q86YN6|UniProtKB:Q9UBK2	F	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha	UniProtKB:Q9UBK2|PTN002496178	protein	taxon:9606	20170228	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	Q9ULJ6	ZMIZ1	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000081664|UniProtKB:Q8NF64	F	Zinc finger MIZ domain-containing protein 1	UniProtKB:Q9ULJ6|PTN002473586	protein	taxon:9606	20190426	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	Q8NI08	NCOA7	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN002763768|UniProtKB:Q8NI08	F	Nuclear receptor coactivator 7	UniProtKB:Q8NI08|PTN002511601	protein	taxon:9606	20200203	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	Q14686	NCOA6	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000403110|UniProtKB:Q14686	F	Nuclear receptor coactivator 6	UniProtKB:Q14686|PTN002496398	protein	taxon:9606	20170228	GO_Central		
`
### gorule-0000022

Check for, and filter, annotations made to retracted publications

* total: 0
### gorule-0000027

Each identifier in GAF is valid

* total: 8
#### Messages
* WARNING - Invalid identifier: GORULE:0000027: 41131609 does not match any id_syntax patterns for RGD in dbxrefs (RGD:41131609) -- `UniProtKB	P19961	AMY2B	enables	GO:0004556	GO_REF:0000033	IBA	PANTHER:PTN008108699|RGD:1593187|FB:FBgn0020506|UniProtKB:P04746|UniProtKB:P0DUB6|UniProtKB:P0DTE7|FB:FBgn0000079|UniProtKB:P0DTE8|RGD:41131609	F	Alpha-amylase 2B	UniProtKB:P19961|PTN002535489	protein	taxon:9606	20240920	GO_Central		
`
* WARNING - Invalid identifier: GORULE:0000027: 15003269 does not match any id_syntax patterns for RGD in dbxrefs (RGD:15003269) -- `UniProtKB	Q93100	PHKB	part_of	GO:0005964	GO_REF:0000033	IBA	PANTHER:PTN000844181|RGD:620186|RGD:15003269|RGD:621522	C	Phosphorylase b kinase regulatory subunit beta	UniProtKB:Q93100|PTN002473396	protein	taxon:9606	20240918	GO_Central		
`
* WARNING - Invalid identifier: GORULE:0000027: 41131609 does not match any id_syntax patterns for RGD in dbxrefs (RGD:41131609) -- `UniProtKB	P0DUB6	AMY1A	enables	GO:0004556	GO_REF:0000033	IBA	PANTHER:PTN008108699|RGD:1593187|FB:FBgn0020506|UniProtKB:P04746|UniProtKB:P0DUB6|UniProtKB:P0DTE7|FB:FBgn0000079|UniProtKB:P0DTE8|RGD:41131609	F	Alpha-amylase 1A	UniProtKB:P0DUB6|PTN002535487	protein	taxon:9606	20240920	GO_Central		
`
* WARNING - Invalid identifier: GORULE:0000027: 15003269 does not match any id_syntax patterns for RGD in dbxrefs (RGD:15003269) -- `UniProtKB	P46019	PHKA2	part_of	GO:0005964	GO_REF:0000033	IBA	PANTHER:PTN000844181|RGD:620186|RGD:15003269|RGD:621522	C	Phosphorylase b kinase regulatory subunit alpha, liver isoform	UniProtKB:P46019|PTN002473398	protein	taxon:9606	20240918	GO_Central		
`
* WARNING - Invalid identifier: GORULE:0000027: 41131609 does not match any id_syntax patterns for RGD in dbxrefs (RGD:41131609) -- `UniProtKB	P04746	AMY2A	enables	GO:0004556	GO_REF:0000033	IBA	PANTHER:PTN008108699|RGD:1593187|FB:FBgn0020506|UniProtKB:P04746|UniProtKB:P0DUB6|UniProtKB:P0DTE7|FB:FBgn0000079|UniProtKB:P0DTE8|RGD:41131609	F	Pancreatic alpha-amylase	UniProtKB:P04746|PTN002535488	protein	taxon:9606	20240920	GO_Central		
`
* WARNING - Invalid identifier: GORULE:0000027: 41131609 does not match any id_syntax patterns for RGD in dbxrefs (RGD:41131609) -- `UniProtKB	P0DTE8	AMY1C	enables	GO:0004556	GO_REF:0000033	IBA	PANTHER:PTN008108699|RGD:1593187|FB:FBgn0020506|UniProtKB:P04746|UniProtKB:P0DUB6|UniProtKB:P0DTE7|FB:FBgn0000079|UniProtKB:P0DTE8|RGD:41131609	F	Alpha-amylase 1C	UniProtKB:P0DTE8|PTN008681860	protein	taxon:9606	20240920	GO_Central		
`
* WARNING - Invalid identifier: GORULE:0000027: 41131609 does not match any id_syntax patterns for RGD in dbxrefs (RGD:41131609) -- `UniProtKB	P0DTE7	AMY1B	enables	GO:0004556	GO_REF:0000033	IBA	PANTHER:PTN008108699|RGD:1593187|FB:FBgn0020506|UniProtKB:P04746|UniProtKB:P0DUB6|UniProtKB:P0DTE7|FB:FBgn0000079|UniProtKB:P0DTE8|RGD:41131609	F	Alpha-amylase 1B	UniProtKB:P0DTE7|PTN008681859	protein	taxon:9606	20240920	GO_Central		
`
* WARNING - Invalid identifier: GORULE:0000027: 15003269 does not match any id_syntax patterns for RGD in dbxrefs (RGD:15003269) -- `UniProtKB	P46020	PHKA1	part_of	GO:0005964	GO_REF:0000033	IBA	PANTHER:PTN000844181|RGD:620186|RGD:15003269|RGD:621522	C	Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform	UniProtKB:P46020|PTN002473399	protein	taxon:9606	20240918	GO_Central		
`
### gorule-0000028

GO aspect should match the term's namespace; otherwise it is repaired to the appropriate aspect

* total: 0
### gorule-0000029

IEAs should be less than one year old.

* total: 0
### gorule-0000030

Obsolete GO_REFs are not allowed

* total: 0
### gorule-0000037

IBA annotations should ONLY be assigned_by GO_Central and have GO_REF:0000033 as a reference

* total: 0
### gorule-0000039

Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants

* total: 0
### gorule-0000042

Qualifier: IKR evidence code requires a NOT qualifier

* total: 0
### gorule-0000043

Check for valid combination of evidence code and GO_REF

* total: 0
### gorule-0000046

The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

* total: 5
#### Messages
* WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- `UniProtKB	Q9NT68	TENM2	enables	GO:0042803	GO_REF:0000033	IBA	PANTHER:PTN000131466|MGI:MGI:1345184|MGI:MGI:2447063|MGI:MGI:1345185	F	Teneurin-2	UniProtKB:Q9NT68|PTN002477321	protein	taxon:9606	20200807	GO_Central		
`
* WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- `UniProtKB	Q9UKZ4	TENM1	enables	GO:0042803	GO_REF:0000033	IBA	PANTHER:PTN000131466|MGI:MGI:1345184|MGI:MGI:2447063|MGI:MGI:1345185	F	Teneurin-1	UniProtKB:Q9UKZ4|PTN002477330	protein	taxon:9606	20200807	GO_Central		
`
* WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- `UniProtKB	Q9P273	TENM3	enables	GO:0042803	GO_REF:0000033	IBA	PANTHER:PTN000131466|MGI:MGI:1345184|MGI:MGI:2447063|MGI:MGI:1345185	F	Teneurin-3	UniProtKB:Q9P273|PTN002477326	protein	taxon:9606	20200807	GO_Central		
`
* WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- `UniProtKB	Q9ULX5	RNF112	involved_in	GO:0051260	GO_REF:0000033	IBA	PANTHER:PTN000844237|FB:FBgn0039213|UniProtKB:Q8WXF7|UniProtKB:Q6DD88|UniProtKB:Q8NHH9	P	RING finger protein 112	UniProtKB:Q9ULX5|PTN002473427	protein	taxon:9606	20190207	GO_Central		
`
* WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- `UniProtKB	Q6N022	TENM4	enables	GO:0042803	GO_REF:0000033	IBA	PANTHER:PTN000131466|MGI:MGI:1345184|MGI:MGI:2447063|MGI:MGI:1345185	F	Teneurin-4	UniProtKB:Q6N022|PTN002477336	protein	taxon:9606	20200807	GO_Central		
`
### gorule-0000050

Annotations to ISS, ISA and ISO should not be self-referential

* total: 0
### gorule-0000055

References should have only one ID per ID space

* total: 0
### gorule-0000058

Object extensions should conform to the extensions-patterns.yaml file in metadata

* total: 0
### gorule-0000061

Allowed gene product to term relations (gp2term)

* total: 0
### gorule-0000063

Annotations using ISS/ISA/ISO evidence should refer to a gene product (in the 'with' column)

* total: 0
### gorule-0000064

TreeGrafter IEAs should be filtered for GO reference species

* total: 0
### gorule-0000065

Annotations to term that are candidates for obsoletion should be removed

* total: 5
#### Messages
* WARNING - Violates GO Rule: GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed -- `UniProtKB	Q9NYY1	IL20	involved_in	GO:2000273	GO_REF:0000033	IBA	PANTHER:PTN009232391|UniProtKB:P22301	P	Interleukin-20	UniProtKB:Q9NYY1|PTN009232403	protein	taxon:9606	20241010	GO_Central		
`
* WARNING - Violates GO Rule: GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed -- `UniProtKB	Q9UHD0	IL19	involved_in	GO:2000273	GO_REF:0000033	IBA	PANTHER:PTN009232391|UniProtKB:P22301	P	Interleukin-19	UniProtKB:Q9UHD0|PTN009232450	protein	taxon:9606	20241010	GO_Central		
`
* WARNING - Violates GO Rule: GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed -- `UniProtKB	Q9NPH9	IL26	involved_in	GO:2000273	GO_REF:0000033	IBA	PANTHER:PTN009232391|UniProtKB:P22301	P	Interleukin-26	UniProtKB:Q9NPH9|PTN009232491	protein	taxon:9606	20241010	GO_Central		
`
* WARNING - Violates GO Rule: GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed -- `UniProtKB	P22301	IL10	involved_in	GO:2000273	GO_REF:0000033	IBA	PANTHER:PTN009232391|UniProtKB:P22301	P	Interleukin-10	UniProtKB:P22301|PTN009232513	protein	taxon:9606	20241010	GO_Central		
`
* WARNING - Violates GO Rule: GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed -- `UniProtKB	Q13007	IL24	involved_in	GO:2000273	GO_REF:0000033	IBA	PANTHER:PTN009232391|UniProtKB:P22301	P	Interleukin-24	UniProtKB:Q13007|PTN009232429	protein	taxon:9606	20241010	GO_Central		
`
### other

* total: 0