# Group: paint - Dataset: paint_zfin

## SUMMARY

This report generated on 2024-12-19

  * Associations: 75981
  * Lines in file (incl headers): 76040
  * Lines skipped: 53
## Header From Original Association File

> !gaf-version: 2.2  
> !Created on Thu Nov 21 14:20:18 2024.  
> !generated-by: PANTHER  
> !date-generated: 2024-11-21  
> !PANTHER version: v.19.0.  
> !GO version: 2024-11-03.  

## Contents

[gorule-0000002](#gorule-0000002)

[gorule-0000005](#gorule-0000005)

[gorule-0000006](#gorule-0000006)

[gorule-0000007](#gorule-0000007)

[gorule-0000008](#gorule-0000008)

[gorule-0000011](#gorule-0000011)

[gorule-0000013](#gorule-0000013)

[gorule-0000015](#gorule-0000015)

[gorule-0000016](#gorule-0000016)

[gorule-0000017](#gorule-0000017)

[gorule-0000018](#gorule-0000018)

[gorule-0000020](#gorule-0000020)

[gorule-0000022](#gorule-0000022)

[gorule-0000027](#gorule-0000027)

[gorule-0000028](#gorule-0000028)

[gorule-0000029](#gorule-0000029)

[gorule-0000030](#gorule-0000030)

[gorule-0000037](#gorule-0000037)

[gorule-0000039](#gorule-0000039)

[gorule-0000042](#gorule-0000042)

[gorule-0000043](#gorule-0000043)

[gorule-0000046](#gorule-0000046)

[gorule-0000050](#gorule-0000050)

[gorule-0000055](#gorule-0000055)

[gorule-0000058](#gorule-0000058)

[gorule-0000061](#gorule-0000061)

[gorule-0000063](#gorule-0000063)

[gorule-0000064](#gorule-0000064)

[gorule-0000065](#gorule-0000065)

[other](#other)


## MESSAGES

### gorule-0000002

No 'NOT' annotations to binding ; GO:0005488 or 'protein binding ; GO:0005515'

* total: 0
### gorule-0000005

IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to to 'protein binding ; GO:0005515 or GO:0005488 binding''

* total: 0
### gorule-0000006

IEP and HEP usage is restricted to terms from the Biological Process ontology, except when assigned by GOC

* total: 0
### gorule-0000007

IPI should not be used with GO:0003824 catalytic activity or descendents

* total: 0
### gorule-0000008

No annotations should be made to uninformative high level terms

* total: 0
### gorule-0000011

ND evidence code should be to root nodes only, and no terms other than root nodes can have the evidence code ND

* total: 0
### gorule-0000013

Taxon-appropriate annotation check

* total: 30
#### Messages
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	A0A8M3BAY8	mark2b	enables	GO:0050321	GO_REF:0000033	IBA	PANTHER:PTN000680111|UniProtKB:P27448|FB:FBgn0260934|UniProtKB:Q7KZI7|RGD:708483|UniProtKB:Q96L34	F	non-specific serine_threonine protein kinase	UniProtKB:A0A8M3BAY8|PTN000680245	protein	taxon:7955	20200809	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `ZFIN	ZDB-GENE-090312-2	si:dkeyp-80c12.7	enables	GO:0050321	GO_REF:0000033	IBA	PANTHER:PTN002780427|RGD:70982|MGI:MGI:1861437|UniProtKB:P49841	F	[tau protein] kinase	UniProtKB:B8JIQ1|PTN000622168	protein	taxon:7955	20190426	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `ZFIN	ZDB-GENE-030515-7	nrarpb	is_active_in	GO:0009707	GO_REF:0000033	IBA	PANTHER:PTN002794166|TAIR:locus:2117607	C	Notch-regulated ankyrin repeat-containing protein B	UniProtKB:Q7T3X9|PTN000653918	protein	taxon:7955	20240206	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `ZFIN	ZDB-GENE-030515-6	nrarpa	is_active_in	GO:0009707	GO_REF:0000033	IBA	PANTHER:PTN002794166|TAIR:locus:2117607	C	Notch-regulated ankyrin repeat-containing protein A	UniProtKB:Q7T3Y0|PTN000653919	protein	taxon:7955	20240206	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	A0A8M2BCS1	mark4a	enables	GO:0050321	GO_REF:0000033	IBA	PANTHER:PTN000680111|UniProtKB:P27448|FB:FBgn0260934|UniProtKB:Q7KZI7|RGD:708483|UniProtKB:Q96L34	F	non-specific serine_threonine protein kinase	UniProtKB:A0A8M2BCS1|PTN001217909	protein	taxon:7955	20200809	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `ZFIN	ZDB-GENE-030131-3906	gpd1h	enables	GO:0047952	GO_REF:0000033	IBA	PANTHER:PTN000919759|MGI:MGI:95679|UniProtKB:C8VTT9|SGD:S000005420|SGD:S000002180	F	Glycerol-3-phosphate dehydrogenase [NAD(+)]	UniProtKB:Q7T1E0|PTN000198073	protein	taxon:7955	20241120	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `ZFIN	ZDB-GENE-110805-1	oxtrl	involved_in	GO:0007565	GO_REF:0000033	IBA	PANTHER:PTN002797428|RGD:3239	P	Isotocin receptor-like 1	UniProtKB:E4W698|PTN000662683	protein	taxon:7955	20200330	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	A0A8M2BLD7	LOC101885029	enables	GO:0050321	GO_REF:0000033	IBA	PANTHER:PTN000680111|UniProtKB:P27448|FB:FBgn0260934|UniProtKB:Q7KZI7|RGD:708483|UniProtKB:Q96L34	F	NUAK family SNF1-like kinase 1	UniProtKB:A0A8M2BLD7|PTN009091927	protein	taxon:7955	20200809	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	A0A8M9PIN5	LOC100333844	enables	GO:0050321	GO_REF:0000033	IBA	PANTHER:PTN000680111|UniProtKB:P27448|FB:FBgn0260934|UniProtKB:Q7KZI7|RGD:708483|UniProtKB:Q96L34	F	Serine_threonine-protein kinase NIM1-like	UniProtKB:A0A8M9PIN5|PTN009091888	protein	taxon:7955	20200809	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	A0A8M9PES1	ankrd6a	is_active_in	GO:0009707	GO_REF:0000033	IBA	PANTHER:PTN002794166|TAIR:locus:2117607	C	Ankyrin repeat domain-containing protein 6 isoform X1	UniProtKB:A0A8M9PES1|PTN009084737	protein	taxon:7955	20240206	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	A0A8M9PXN3	mark3a	enables	GO:0050321	GO_REF:0000033	IBA	PANTHER:PTN000680111|UniProtKB:P27448|FB:FBgn0260934|UniProtKB:Q7KZI7|RGD:708483|UniProtKB:Q96L34	F	non-specific serine_threonine protein kinase	UniProtKB:A0A8M9PXN3|PTN000680184	protein	taxon:7955	20200809	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `ZFIN	ZDB-GENE-140106-203	zgc:66101	enables	GO:0050321	GO_REF:0000033	IBA	PANTHER:PTN000680111|UniProtKB:P27448|FB:FBgn0260934|UniProtKB:Q7KZI7|RGD:708483|UniProtKB:Q96L34	F	Serine_threonine-protein kinase SIK3 homolog	UniProtKB:Q6NSM8|PTN001966396	protein	taxon:7955	20200809	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	A0A8M9P2G9	ankrd6b	is_active_in	GO:0009707	GO_REF:0000033	IBA	PANTHER:PTN002794166|TAIR:locus:2117607	C	Ankyrin repeat domain-containing protein 6 isoform X1	UniProtKB:A0A8M9P2G9|PTN000653960	protein	taxon:7955	20240206	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	A0A8M3B1F0	brsk2b	enables	GO:0050321	GO_REF:0000033	IBA	PANTHER:PTN000679673|MGI:MGI:2685946|UniProtKB:Q8TDC3|MGI:MGI:1923020|UniProtKB:Q8IWQ3	F	Serine_threonine-protein kinase BRSK2 isoform X1	UniProtKB:A0A8M3B1F0|PTN001217025	protein	taxon:7955	20230603	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `ZFIN	ZDB-GENE-100330-2	mark4b	enables	GO:0050321	GO_REF:0000033	IBA	PANTHER:PTN000680111|UniProtKB:P27448|FB:FBgn0260934|UniProtKB:Q7KZI7|RGD:708483|UniProtKB:Q96L34	F	MAP_microtubule affinity-regulating kinase 4 isoform X5	UniProtKB:R4GEN1|PTN000680159	protein	taxon:7955	20200809	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `ZFIN	ZDB-GENE-110805-2	oxtr	involved_in	GO:0007565	GO_REF:0000033	IBA	PANTHER:PTN002797428|RGD:3239	P	Isotocin receptor-like 2	UniProtKB:E4W699|PTN000662684	protein	taxon:7955	20200330	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `ZFIN	ZDB-GENE-040801-130	mettl16	enables	GO:0052907	GO_REF:0000033	IBA	PANTHER:PTN000333539|UniProtKB:P75782	F	RNA N6-adenosine-methyltransferase mettl16	UniProtKB:Q6DC64|PTN000333572	protein	taxon:7955	20170228	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	A0A8M3B4V1	mark2a	enables	GO:0050321	GO_REF:0000033	IBA	PANTHER:PTN000680111|UniProtKB:P27448|FB:FBgn0260934|UniProtKB:Q7KZI7|RGD:708483|UniProtKB:Q96L34	F	non-specific serine_threonine protein kinase	UniProtKB:A0A8M3B4V1|PTN001217933	protein	taxon:7955	20200809	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `ZFIN	ZDB-GENE-040426-700	ankrd10	is_active_in	GO:0009707	GO_REF:0000033	IBA	PANTHER:PTN002794166|TAIR:locus:2117607	C	Ankyrin repeat domain 10a	UniProtKB:Q803R0|PTN000653985	protein	taxon:7955	20240206	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `ZFIN	ZDB-GENE-120910-2	tnfrsf11a	involved_in	GO:0048535	GO_REF:0000033	IBA	PANTHER:PTN002932239|MGI:MGI:1314891	P	Tumor necrosis factor receptor superfamily member 11A isoform X1	UniProtKB:E7F027|PTN001133911	protein	taxon:7955	20200211	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `ZFIN	ZDB-GENE-120809-2	rlim	involved_in	GO:0060816	GO_REF:0000033	IBA	PANTHER:PTN002914536|MGI:MGI:1342291|UniProtKB:Q9NVW2	P	E3 ubiquitin-protein ligase RLIM	UniProtKB:E7FH41|PTN001020995	protein	taxon:7955	20200207	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `ZFIN	ZDB-GENE-030131-6313	fi45a07	involved_in	GO:1990810	GO_REF:0000033	IBA	PANTHER:PTN000416664|PomBase:SPBC32H8.09	P	WD repeat-containing protein WRAP73	UniProtKB:B8A4V4|PTN000416692	protein	taxon:7955	20200319	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `ZFIN	ZDB-GENE-990415-234	rag1	involved_in	GO:0002331	GO_REF:0000033	IBA	PANTHER:PTN002610391|MGI:MGI:97848	P	V(D)J recombination-activating protein 1	UniProtKB:O13033|PTN000166142	protein	taxon:7955	20190208	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	A0A8M2B3S3	si:dkey-31m14.7	enables	GO:0050321	GO_REF:0000033	IBA	PANTHER:PTN000680111|UniProtKB:P27448|FB:FBgn0260934|UniProtKB:Q7KZI7|RGD:708483|UniProtKB:Q96L34	F	non-specific serine_threonine protein kinase	UniProtKB:A0A8M2B3S3|PTN009091950	protein	taxon:7955	20200809	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	A0A8M3AVR7	gsk3b	enables	GO:0050321	GO_REF:0000033	IBA	PANTHER:PTN002780427|RGD:70982|MGI:MGI:1861437|UniProtKB:P49841	F	[tau protein] kinase	UniProtKB:A0A8M3AVR7|PTN000624353	protein	taxon:7955	20190426	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `ZFIN	ZDB-GENE-061013-49	si:ch211-235e18.4	is_active_in	GO:0009707	GO_REF:0000033	IBA	PANTHER:PTN002794166|TAIR:locus:2117607	C	Ankyrin repeat domain 10b	UniProtKB:Q08BM2|PTN000653984	protein	taxon:7955	20240206	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	A0A8M3AL25	mark3b	enables	GO:0050321	GO_REF:0000033	IBA	PANTHER:PTN000680111|UniProtKB:P27448|FB:FBgn0260934|UniProtKB:Q7KZI7|RGD:708483|UniProtKB:Q96L34	F	non-specific serine_threonine protein kinase	UniProtKB:A0A8M3AL25|PTN001217913	protein	taxon:7955	20200809	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `UniProtKB	A0A8M2B1T7	LOC559131	enables	GO:0050321	GO_REF:0000033	IBA	PANTHER:PTN000680111|UniProtKB:P27448|FB:FBgn0260934|UniProtKB:Q7KZI7|RGD:708483|UniProtKB:Q96L34	F	Serine_threonine-protein kinase NIM1-like isoform X1	UniProtKB:A0A8M2B1T7|PTN009091886	protein	taxon:7955	20200809	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `ZFIN	ZDB-GENE-050417-209	zgc:112197	enables	GO:0047952	GO_REF:0000033	IBA	PANTHER:PTN000919759|MGI:MGI:95679|UniProtKB:C8VTT9|SGD:S000005420|SGD:S000002180	F	Glycerol-3-phosphate dehydrogenase [NAD(+)]	UniProtKB:Q567A1|PTN000198072	protein	taxon:7955	20241120	GO_Central		
`
* ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- `ZFIN	ZDB-GENE-040426-2576	gpd1	enables	GO:0047952	GO_REF:0000033	IBA	PANTHER:PTN000919759|MGI:MGI:95679|UniProtKB:C8VTT9|SGD:S000005420|SGD:S000002180	F	Glycerol-3-phosphate dehydrogenase [NAD(+)]	UniProtKB:Q7T3H5|PTN000198048	protein	taxon:7955	20241120	GO_Central		
`
### gorule-0000015

Dual species taxon check

* total: 0
### gorule-0000016

With/From: IC annotations require a With/From GO ID

* total: 0
### gorule-0000017

IDA annotations must not have a With/From entry

* total: 0
### gorule-0000018

IPI annotations require a With/From entry

* total: 0
### gorule-0000020

Automatic repair of annotations to merged or obsoleted terms

* total: 56
#### Messages
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0006266) -- `ZFIN	ZDB-GENE-110404-2	si:dkeyp-35b8.5	involved_in	GO:0006266	GO_REF:0000033	IBA	PANTHER:PTN000048696|RGD:1309875|SGD:S000002323|UniProtKB:P49916	P	DNA ligase	UniProtKB:B0S533|PTN002470870	protein	taxon:7955	20241121	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0006288) -- `ZFIN	ZDB-GENE-030131-8453	im:7139055	involved_in	GO:0006288	GO_REF:0000033	IBA	PANTHER:PTN000825510|UniProtKB:P49916|RGD:1309875	P	DNA ligase	UniProtKB:F1QJL4|PTN002470845	protein	taxon:7955	20220517	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0032508) -- `ZFIN	ZDB-GENE-050506-110	rad50	involved_in	GO:0032508	GO_REF:0000033	IBA	PANTHER:PTN000429848|UniProtKB:Q92878	P	DNA repair protein RAD50	UniProtKB:A0A8N7UW22|PTN001051189	protein	taxon:7955	20170228	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0032508) -- `ZFIN	ZDB-GENE-041114-191	ddx11	involved_in	GO:0032508	GO_REF:0000033	IBA	PANTHER:PTN000158371|UniProtKB:Q96FC9	P	ATP-dependent DNA helicase DDX11	UniProtKB:F1R345|PTN000158406	protein	taxon:7955	20200929	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0032508) -- `ZFIN	ZDB-GENE-050306-11	rtel1	involved_in	GO:0032508	GO_REF:0000033	IBA	PANTHER:PTN000158195|MGI:MGI:2139369	P	Regulator of telomere elongation helicase 1	UniProtKB:P0C928|PTN000158405	protein	taxon:7955	20200929	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0032508) -- `ZFIN	ZDB-GENE-041008-35	nbn	involved_in	GO:0032508	GO_REF:0000033	IBA	PANTHER:PTN000255549|UniProtKB:O60934	P	Nibrin	UniProtKB:Q5I2W8|PTN000255580	protein	taxon:7955	20170228	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0042989) -- `ZFIN	ZDB-GENE-040711-3	zgc:92472	involved_in	GO:0042989	GO_REF:0000033	IBA	PANTHER:PTN001011683|SGD:S000003312|MGI:MGI:1346078|MGI:MGI:1100520	P	Twf1b protein	UniProtKB:Q6DKF4|PTN002300973	protein	taxon:7955	20170421	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0042989) -- `ZFIN	ZDB-GENE-050307-5	tmsb	involved_in	GO:0042989	GO_REF:0000033	IBA	PANTHER:PTN002280337|MGI:MGI:3843061|UniProtKB:P62328|UniProtKB:P62326	P	Thymosin beta	UniProtKB:Q9W7M8|PTN000246253	protein	taxon:7955	20221007	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0042989) -- `ZFIN	ZDB-GENE-050522-238	si:ch211-14i3.4	involved_in	GO:0042989	GO_REF:0000033	IBA	PANTHER:PTN001011683|SGD:S000003312|MGI:MGI:1346078|MGI:MGI:1100520	P	Twinfilin actin-binding protein 2b	UniProtKB:E7F2D6|PTN000349084	protein	taxon:7955	20170421	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0042989) -- `ZFIN	ZDB-GENE-131121-583	si:ch211-175f11.5	involved_in	GO:0042989	GO_REF:0000033	IBA	PANTHER:PTN000176159|SGD:S000005648|UniProtKB:P35081|UniProtKB:O22655|UniProtKB:Q8I2J4|UniProtKB:Q9FR39	P	Profilin	UniProtKB:X1WCU6|PTN002266716	protein	taxon:7955	20230110	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0042989) -- `ZFIN	ZDB-GENE-030131-4402	wu:fd02b03	involved_in	GO:0042989	GO_REF:0000033	IBA	PANTHER:PTN001011683|SGD:S000003312|MGI:MGI:1346078|MGI:MGI:1100520	P	Twinfilin, actin-binding protein, homolog 1a	UniProtKB:Q6PEI5|PTN007622610	protein	taxon:7955	20170421	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0042989) -- `ZFIN	ZDB-GENE-030131-8304	Tbeta11	involved_in	GO:0042989	GO_REF:0000033	IBA	PANTHER:PTN002280337|MGI:MGI:3843061|UniProtKB:P62328|UniProtKB:P62326	P	Thymosin beta	UniProtKB:Q45QT2|PTN000246254	protein	taxon:7955	20221007	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0042989) -- `ZFIN	ZDB-GENE-030131-8575	Tbeta-a	involved_in	GO:0042989	GO_REF:0000033	IBA	PANTHER:PTN002280337|MGI:MGI:3843061|UniProtKB:P62328|UniProtKB:P62326	P	Thymosin beta	UniProtKB:A0A097|PTN002635005	protein	taxon:7955	20221007	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0042989) -- `ZFIN	ZDB-GENE-030131-7638	twf2	involved_in	GO:0042989	GO_REF:0000033	IBA	PANTHER:PTN001011683|SGD:S000003312|MGI:MGI:1346078|MGI:MGI:1100520	P	Twinfilin-2	UniProtKB:Q6GMH3|PTN001011695	protein	taxon:7955	20170421	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0044806) -- `ZFIN	ZDB-GENE-070702-2	wrn	involved_in	GO:0044806	GO_REF:0000033	IBA	PANTHER:PTN002492232|UniProtKB:Q14191|MGI:MGI:109635	P	DNA helicase	UniProtKB:A0A0R4IT14|PTN001009185	protein	taxon:7955	20190113	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0044806) -- `UniProtKB	A0A8M6YUA3	blm	involved_in	GO:0044806	GO_REF:0000033	IBA	PANTHER:PTN002672422|MGI:MGI:1328362|UniProtKB:P54132	P	DNA helicase	UniProtKB:A0A8M6YUA3|PTN001009196	protein	taxon:7955	20190319	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0051103) -- `ZFIN	ZDB-GENE-040426-1755	zgc:73312	involved_in	GO:0051103	GO_REF:0000033	IBA	PANTHER:PTN002004633|UniProtKB:Q13426	P	DNA repair protein XRCC4 isoform X1	UniProtKB:A0A2R8RHK7|PTN002004644	protein	taxon:7955	20190520	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0051220) -- `ZFIN	ZDB-GENE-131127-646	si:ch73-193c12.2	involved_in	GO:0051220	GO_REF:0000033	IBA	PANTHER:PTN002866991|UniProtKB:Q16643	P	Si:ch73-193c12.2	UniProtKB:E7FBI6|PTN002214946	protein	taxon:7955	20230720	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0051220) -- `ZFIN	ZDB-GENE-030131-2059	fb95f07	involved_in	GO:0051220	GO_REF:0000033	IBA	PANTHER:PTN002866991|UniProtKB:Q16643	P	Uncharacterized protein LOC562056	UniProtKB:A8KB19|PTN002214951	protein	taxon:7955	20230720	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0051220) -- `UniProtKB	A0A8M3AWK6	LOC103911722	involved_in	GO:0051220	GO_REF:0000033	IBA	PANTHER:PTN002866991|UniProtKB:Q16643	P	Interaptin-like	UniProtKB:A0A8M3AWK6|PTN009162934	protein	taxon:7955	20230720	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0051220) -- `ZFIN	ZDB-GENE-081104-62	si:dkeyp-38g8.5	involved_in	GO:0051220	GO_REF:0000033	IBA	PANTHER:PTN002866991|UniProtKB:Q16643	P	Si:dkeyp-38g8.5	UniProtKB:B0S5X1|PTN002214952	protein	taxon:7955	20230720	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0051220) -- `ZFIN	ZDB-GENE-050913-149	zgc:113426	involved_in	GO:0051220	GO_REF:0000033	IBA	PANTHER:PTN002866991|UniProtKB:Q16643	P	Uncharacterized protein LOC562128	UniProtKB:F6P8H4|PTN002446114	protein	taxon:7955	20230720	GO_Central		
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0070643) -- `ZFIN	ZDB-GENE-060825-1	cyp24a1l	enables	GO:0070643	GO_REF:0000033	IBA	PANTHER:PTN002801018|RGD:2462|UniProtKB:Q07973	F	1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	UniProtKB:A3KNB0|PTN000669381	protein	taxon:7955	20200206	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `ZFIN	ZDB-GENE-050417-340	ssbp1	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000033807|FB:FBgn0010438|UniProtKB:Q04837	P	Single-stranded DNA-binding protein, mitochondrial	UniProtKB:B8A5I7|PTN000033835	protein	taxon:7955	20240820	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `UniProtKB	A0A8M6YUA3	blm	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000344874|SGD:S000004802	P	DNA helicase	UniProtKB:A0A8M6YUA3|PTN001009196	protein	taxon:7955	20190319	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `ZFIN	ZDB-GENE-070702-2	wrn	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000344874|SGD:S000004802	P	DNA helicase	UniProtKB:A0A0R4IT14|PTN001009185	protein	taxon:7955	20190319	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `ZFIN	ZDB-GENE-020419-27	sr:nyz175	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000180038|MGI:MGI:1298398|UniProtKB:P33993|SGD:S000000406	P	DNA replication licensing factor MCM7	UniProtKB:Q7ZVL6|PTN000908136	protein	taxon:7955	20211215	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `ZFIN	ZDB-GENE-091112-2	recql4	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000344874|SGD:S000004802	P	ATP-dependent DNA helicase Q4	UniProtKB:E7F2M7|PTN001009523	protein	taxon:7955	20190319	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `ZFIN	ZDB-GENE-030131-9544	cb1025	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000179968|SGD:S000006223|UniProtKB:P33991|MGI:MGI:103199	P	DNA replication licensing factor MCM4	UniProtKB:Q6NZV2|PTN000180003	protein	taxon:7955	20211215	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `ZFIN	ZDB-GENE-071214-1	recql5	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000344874|SGD:S000004802	P	ATP-dependent DNA helicase	UniProtKB:X1WCM8|PTN000344991	protein	taxon:7955	20190319	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `ZFIN	ZDB-GENE-030912-3	rpa1	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000588618|SGD:S000000065	P	Replication protein A 70 kDa DNA-binding subunit	UniProtKB:Q6NY74|PTN000588651	protein	taxon:7955	20210531	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `ZFIN	ZDB-GENE-030909-6	im:7140796	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000180096|MGI:MGI:1298227|UniProtKB:Q14566|SGD:S000003169	P	DNA replication licensing factor MCM6	UniProtKB:A3KMS0|PTN000180130	protein	taxon:7955	20211215	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `ZFIN	ZDB-GENE-050913-141	MCM6m	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000180096|MGI:MGI:1298227|UniProtKB:Q14566|SGD:S000003169	P	DNA replication licensing factor MCM6	UniProtKB:Q4V9J1|PTN000180129	protein	taxon:7955	20211215	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `ZFIN	ZDB-GENE-020419-24	cb737	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000179907|UniProtKB:Q2R482|MGI:MGI:105380|UniProtKB:P49736	P	DNA replication licensing factor MCM2	UniProtKB:A0A0R4IF65|PTN001360276	protein	taxon:7955	20211215	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006268) -- `UniProtKB	A0A8M9PHB7	recql	involved_in	GO:0006268	GO_REF:0000033	IBA	PANTHER:PTN000344874|SGD:S000004802	P	ATP-dependent DNA helicase	UniProtKB:A0A8M9PHB7|PTN009012115	protein	taxon:7955	20190319	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006977) -- `ZFIN	ZDB-GENE-041010-168	zgc:101717	involved_in	GO:0006977	GO_REF:0000033	IBA	PANTHER:PTN008354075|UniProtKB:P78560	P	CASP2 and RIPK1 domain-containing adaptor with death domain	UniProtKB:Q5XJP2|PTN000385774	protein	taxon:7955	20240924	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006977) -- `ZFIN	ZDB-GENE-131127-252	si:dkey-29h14.10	involved_in	GO:0006977	GO_REF:0000033	IBA	PANTHER:PTN008354075|UniProtKB:P78560	P	Si:dkey-29h14.10	UniProtKB:A0A0R4ISE6|PTN008557661	protein	taxon:7955	20240924	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006978) -- `ZFIN	ZDB-GENE-030131-9616	rps6ka6	involved_in	GO:0006978	GO_REF:0000033	IBA	PANTHER:PTN002806567|UniProtKB:Q9UK32	P	Ribosomal protein S6 kinase alpha-6	UniProtKB:Q6PFQ0|PTN001219221	protein	taxon:7955	20200917	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006978) -- `UniProtKB	A0A8M3B8E3	rps6kal	involved_in	GO:0006978	GO_REF:0000033	IBA	PANTHER:PTN002806567|UniProtKB:Q9UK32	P	non-specific serine_threonine protein kinase	UniProtKB:A0A8M3B8E3|PTN009093216	protein	taxon:7955	20200917	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	A0A8M9PVT8	LOC110440113	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000399017|UniProtKB:Q86YN6|UniProtKB:Q9UBK2	F	Peroxisome proliferator-activated receptor gamma coactivator-related protein 1-like	UniProtKB:A0A8M9PVT8|PTN009025817	protein	taxon:7955	20170228	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	E7FGS2	LOC792958	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN002763768|UniProtKB:Q8NI08	F	Nuclear receptor coactivator 7-like	UniProtKB:E7FGS2|PTN001156520	protein	taxon:7955	20200203	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `ZFIN	ZDB-GENE-070410-27	sfr1	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN002008993|UniProtKB:Q86XK3	F	Swi5-dependent recombination DNA repair protein 1 homolog	UniProtKB:B7ZD04|PTN002009005	protein	taxon:7955	20171117	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `ZFIN	ZDB-GENE-080403-12	ncoa6	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000403110|UniProtKB:Q14686	F	Nuclear receptor coactivator 6	UniProtKB:F1R869|PTN001038596	protein	taxon:7955	20170228	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	A0A8M2BFX4	dcaf6	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000400123|UniProtKB:Q58WW2	F	DDB1- and CUL4-associated factor 6 isoform X1	UniProtKB:A0A8M2BFX4|PTN009026096	protein	taxon:7955	20190726	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	A0A8M2B372	zmiz1a	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000081664|UniProtKB:Q8NF64	F	Zinc finger MIZ domain-containing protein 1 isoform X1	UniProtKB:A0A8M2B372|PTN000845890	protein	taxon:7955	20190426	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `ZFIN	ZDB-GENE-090313-285	zmiz2	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000081664|UniProtKB:Q8NF64	F	Zinc finger MIZ domain-containing protein 2 isoform X1	UniProtKB:A0A8M2B1Q3|PTN000845882	protein	taxon:7955	20190426	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	A0A8M2BL77	sra1	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN001050482|RGD:621148	F	Steroid receptor RNA activator 1 isoform X1	UniProtKB:A0A8M2BL77|PTN000428450	protein	taxon:7955	20241120	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	A0A8M6Z3G5	LOC569262	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN002763768|UniProtKB:Q8NI08	F	Nuclear receptor coactivator 7-like isoform X1	UniProtKB:A0A8M6Z3G5|PTN009071393	protein	taxon:7955	20200203	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	A0A8M6Z7F8	ppargc1a	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000399017|UniProtKB:Q86YN6|UniProtKB:Q9UBK2	F	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1	UniProtKB:A0A8M6Z7F8|PTN001036567	protein	taxon:7955	20170228	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	A0A8M1P1P0	si:dkey-93h22.8	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000399017|UniProtKB:Q86YN6|UniProtKB:Q9UBK2	F	Uncharacterized protein LOC449943	UniProtKB:A0A8M1P1P0|PTN002496182	protein	taxon:7955	20170228	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	A0A8M3AP47	ppargc1b	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000399017|UniProtKB:Q86YN6|UniProtKB:Q9UBK2	F	Peroxisome proliferator-activated receptor gamma coactivator 1-beta	UniProtKB:A0A8M3AP47|PTN002311055	protein	taxon:7955	20170228	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `ZFIN	ZDB-GENE-041001-175	ncoa1	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000074430|UniProtKB:Q15788|RGD:620109|FB:FBgn0041092|MGI:MGI:1276535|UniProtKB:Q9Y6Q9|UniProtKB:Q15596|MGI:MGI:1276533	F	Nuclear receptor coactivator 1	UniProtKB:A0A8M9PTD7|PTN000841420	protein	taxon:7955	20241119	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `ZFIN	ZDB-GENE-010406-3	ncoa2	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000074430|UniProtKB:Q15788|RGD:620109|FB:FBgn0041092|MGI:MGI:1276535|UniProtKB:Q9Y6Q9|UniProtKB:Q15596|MGI:MGI:1276533	F	Nuclear receptor coactivator 2	UniProtKB:Q98TW1|PTN000074493	protein	taxon:7955	20241119	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	A0A8M2B4Y3	si:ch211-15d5.11	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN002763768|UniProtKB:Q8NI08	F	Oxidation resistance protein 1-like isoform X1	UniProtKB:A0A8M2B4Y3|PTN002360767	protein	taxon:7955	20200203	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `UniProtKB	A0A8M9QDK0	ncoa3	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000074430|UniProtKB:Q15788|RGD:620109|FB:FBgn0041092|MGI:MGI:1276535|UniProtKB:Q9Y6Q9|UniProtKB:Q15596|MGI:MGI:1276533	F	Nuclear receptor coactivator 3 isoform X1	UniProtKB:A0A8M9QDK0|PTN002473104	protein	taxon:7955	20241119	GO_Central		
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0030374) -- `ZFIN	ZDB-GENE-030131-9858	pprc1	enables	GO:0030374	GO_REF:0000033	IBA	PANTHER:PTN000399017|UniProtKB:Q86YN6|UniProtKB:Q9UBK2	F	PPARG-related coactivator 1	UniProtKB:E7F4W0|PTN001036574	protein	taxon:7955	20170228	GO_Central		
`
### gorule-0000022

Check for, and filter, annotations made to retracted publications

* total: 0
### gorule-0000027

Each identifier in GAF is valid

* total: 6
#### Messages
* WARNING - Invalid identifier: GORULE:0000027: 15003269 does not match any id_syntax patterns for RGD in dbxrefs (RGD:15003269) -- `ZFIN	ZDB-GENE-091204-81	phka1b	part_of	GO:0005964	GO_REF:0000033	IBA	PANTHER:PTN000844181|RGD:620186|RGD:15003269|RGD:621522	C	Phosphorylase b kinase regulatory subunit	UniProtKB:A0A286YBM7|PTN000844209	protein	taxon:7955	20240918	GO_Central		
`
* WARNING - Invalid identifier: GORULE:0000027: 41131609 does not match any id_syntax patterns for RGD in dbxrefs (RGD:41131609) -- `ZFIN	ZDB-GENE-040801-179	amy2al2	enables	GO:0004556	GO_REF:0000033	IBA	PANTHER:PTN008108699|RGD:1593187|FB:FBgn0020506|UniProtKB:P04746|UniProtKB:P0DUB6|UniProtKB:P0DTE7|FB:FBgn0000079|UniProtKB:P0DTE8|RGD:41131609	F	Alpha-amylase	UniProtKB:Q6DHR7|PTN000039925	protein	taxon:7955	20240920	GO_Central		
`
* WARNING - Invalid identifier: GORULE:0000027: 41131609 does not match any id_syntax patterns for RGD in dbxrefs (RGD:41131609) -- `ZFIN	ZDB-GENE-040426-2393	amy3	enables	GO:0004556	GO_REF:0000033	IBA	PANTHER:PTN008108699|RGD:1593187|FB:FBgn0020506|UniProtKB:P04746|UniProtKB:P0DUB6|UniProtKB:P0DTE7|FB:FBgn0000079|UniProtKB:P0DTE8|RGD:41131609	F	Alpha-amylase	UniProtKB:Q6P5J0|PTN000039926	protein	taxon:7955	20240920	GO_Central		
`
* WARNING - Invalid identifier: GORULE:0000027: 15003269 does not match any id_syntax patterns for RGD in dbxrefs (RGD:15003269) -- `UniProtKB	A0A8M9QI67	phka2	part_of	GO:0005964	GO_REF:0000033	IBA	PANTHER:PTN000844181|RGD:620186|RGD:15003269|RGD:621522	C	Phosphorylase b kinase regulatory subunit	UniProtKB:A0A8M9QI67|PTN000079035	protein	taxon:7955	20240918	GO_Central		
`
* WARNING - Invalid identifier: GORULE:0000027: 15003269 does not match any id_syntax patterns for RGD in dbxrefs (RGD:15003269) -- `ZFIN	ZDB-GENE-110411-149	phkb	part_of	GO:0005964	GO_REF:0000033	IBA	PANTHER:PTN000844181|RGD:620186|RGD:15003269|RGD:621522	C	Phosphorylase b kinase regulatory subunit	UniProtKB:F1Q6F0|PTN000844185	protein	taxon:7955	20240918	GO_Central		
`
* WARNING - Invalid identifier: GORULE:0000027: 41131609 does not match any id_syntax patterns for RGD in dbxrefs (RGD:41131609) -- `ZFIN	ZDB-GENE-040426-1606	zgc:66313	enables	GO:0004556	GO_REF:0000033	IBA	PANTHER:PTN008108699|RGD:1593187|FB:FBgn0020506|UniProtKB:P04746|UniProtKB:P0DUB6|UniProtKB:P0DTE7|FB:FBgn0000079|UniProtKB:P0DTE8|RGD:41131609	F	Alpha-amylase	UniProtKB:A0A8M2B5V6|PTN000039924	protein	taxon:7955	20240920	GO_Central		
`
### gorule-0000028

GO aspect should match the term's namespace; otherwise it is repaired to the appropriate aspect

* total: 0
### gorule-0000029

IEAs should be less than one year old.

* total: 0
### gorule-0000030

Obsolete GO_REFs are not allowed

* total: 0
### gorule-0000037

IBA annotations should ONLY be assigned_by GO_Central and have GO_REF:0000033 as a reference

* total: 0
### gorule-0000039

Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants

* total: 0
### gorule-0000042

Qualifier: IKR evidence code requires a NOT qualifier

* total: 0
### gorule-0000043

Check for valid combination of evidence code and GO_REF

* total: 0
### gorule-0000046

The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

* total: 13
#### Messages
* WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- `ZFIN	ZDB-GENE-030131-6505	wu:fc06e01	involved_in	GO:0051260	GO_REF:0000033	IBA	PANTHER:PTN000844237|FB:FBgn0039213|UniProtKB:Q8WXF7|UniProtKB:Q6DD88|UniProtKB:Q8NHH9	P	Atl2 protein	UniProtKB:A8KAZ3|PTN002243344	protein	taxon:7955	20190207	GO_Central		
`
* WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- `ZFIN	ZDB-GENE-040227-1	gnmt	involved_in	GO:0051289	GO_REF:0000033	IBA	PANTHER:PTN001046627|RGD:2719|UniProtKB:Q14749|MGI:MGI:1202304	P	Glycine N-methyltransferase	UniProtKB:Q6P607|PTN000420025	protein	taxon:7955	20180916	GO_Central		
`
* WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- `ZFIN	ZDB-GENE-050506-30	vps25	enables	GO:0042803	GO_REF:0000033	IBA	PANTHER:PTN000322234|UniProtKB:Q9BRG1	F	Vacuolar protein-sorting-associated protein 25	UniProtKB:Q6NWF4|PTN000322263	protein	taxon:7955	20170228	GO_Central		
`
* WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- `UniProtKB	A0A8M9PCP4	pde2a	enables	GO:0042803	GO_REF:0000033	IBA	PANTHER:PTN000886790|UniProtKB:O00408|MGI:MGI:2446107	F	Phosphodiesterase	UniProtKB:A0A8M9PCP4|PTN008965914	protein	taxon:7955	20180916	GO_Central		
`
* WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- `UniProtKB	A0A8M9QGV6	si:dkey-237h12.3	enables	GO:0042803	GO_REF:0000033	IBA	PANTHER:PTN000131466|MGI:MGI:1345184|MGI:MGI:2447063|MGI:MGI:1345185	F	Teneurin-3 isoform X1	UniProtKB:A0A8M9QGV6|PTN000880707	protein	taxon:7955	20200807	GO_Central		
`
* WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- `ZFIN	ZDB-GENE-041010-109	im:6911985	involved_in	GO:0051260	GO_REF:0000033	IBA	PANTHER:PTN000844237|FB:FBgn0039213|UniProtKB:Q8WXF7|UniProtKB:Q6DD88|UniProtKB:Q8NHH9	P	Atlastin 3	UniProtKB:A2CEM4|PTN000079145	protein	taxon:7955	20190207	GO_Central		
`
* WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- `UniProtKB	A0A8M9QKX8	si:dkey-34l15.2	enables	GO:0042803	GO_REF:0000033	IBA	PANTHER:PTN000131466|MGI:MGI:1345184|MGI:MGI:2447063|MGI:MGI:1345185	F	Teneurin-2 isoform X1	UniProtKB:A0A8M9QKX8|PTN002477323	protein	taxon:7955	20200807	GO_Central		
`
* WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- `ZFIN	ZDB-GENE-030131-8003	fj46c01	involved_in	GO:0051260	GO_REF:0000033	IBA	PANTHER:PTN000844237|FB:FBgn0039213|UniProtKB:Q8WXF7|UniProtKB:Q6DD88|UniProtKB:Q8NHH9	P	Atlastin GTPase 1	UniProtKB:E9QGX9|PTN000079170	protein	taxon:7955	20190207	GO_Central		
`
* WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- `ZFIN	ZDB-GENE-070112-1442	zgc:158270	involved_in	GO:0051260	GO_REF:0000033	IBA	PANTHER:PTN000844237|FB:FBgn0039213|UniProtKB:Q8WXF7|UniProtKB:Q6DD88|UniProtKB:Q8NHH9	P	Uncharacterized protein LOC791213	UniProtKB:A1L1R4|PTN008952536	protein	taxon:7955	20190207	GO_Central		
`
* WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- `UniProtKB	A0A8N7UV98	tenm1	enables	GO:0042803	GO_REF:0000033	IBA	PANTHER:PTN000131466|MGI:MGI:1345184|MGI:MGI:2447063|MGI:MGI:1345185	F	Teneurin-1 isoform X1	UniProtKB:A0A8N7UV98|PTN000880701	protein	taxon:7955	20200807	GO_Central		
`
* WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- `UniProtKB	A0A8M9PRF5	si:ch211-12m10.1	enables	GO:0042803	GO_REF:0000033	IBA	PANTHER:PTN000131466|MGI:MGI:1345184|MGI:MGI:2447063|MGI:MGI:1345185	F	Teneurin-2 isoform X1	UniProtKB:A0A8M9PRF5|PTN000198589	protein	taxon:7955	20200807	GO_Central		
`
* WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- `ZFIN	ZDB-GENE-990714-19	tenm3	enables	GO:0042803	GO_REF:0000033	IBA	PANTHER:PTN000131466|MGI:MGI:1345184|MGI:MGI:2447063|MGI:MGI:1345185	F	Teneurin-3	UniProtKB:Q9W7R4|PTN000880708	protein	taxon:7955	20200807	GO_Central		
`
* WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- `ZFIN	ZDB-GENE-990714-20	tenm4	enables	GO:0042803	GO_REF:0000033	IBA	PANTHER:PTN000131466|MGI:MGI:1345184|MGI:MGI:2447063|MGI:MGI:1345185	F	Teneurin-4	UniProtKB:Q9W7R3|PTN000131519	protein	taxon:7955	20200807	GO_Central		
`
### gorule-0000050

Annotations to ISS, ISA and ISO should not be self-referential

* total: 0
### gorule-0000055

References should have only one ID per ID space

* total: 0
### gorule-0000058

Object extensions should conform to the extensions-patterns.yaml file in metadata

* total: 0
### gorule-0000061

Allowed gene product to term relations (gp2term)

* total: 0
### gorule-0000063

Annotations using ISS/ISA/ISO evidence should refer to a gene product (in the 'with' column)

* total: 0
### gorule-0000064

TreeGrafter IEAs should be filtered for GO reference species

* total: 0
### gorule-0000065

Annotations to term that are candidates for obsoletion should be removed

* total: 2
#### Messages
* WARNING - Violates GO Rule: GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed -- `ZFIN	ZDB-GENE-051111-1	zgc:194510	involved_in	GO:2000273	GO_REF:0000033	IBA	PANTHER:PTN009232391|UniProtKB:P22301	P	Interleukin family protein	UniProtKB:Q5EFQ8|PTN009232552	protein	taxon:7955	20241010	GO_Central		
`
* WARNING - Violates GO Rule: GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed -- `ZFIN	ZDB-GENE-071121-1	il19l	involved_in	GO:2000273	GO_REF:0000033	IBA	PANTHER:PTN009232391|UniProtKB:P22301	P	Interleukin family protein	UniProtKB:Q4LDR4|PTN009232477	protein	taxon:7955	20241010	GO_Central		
`
### other

* total: 0