{ "graphs" : [ { "id" : "http://purl.obolibrary.org/obo/go/subsets/gocheck_do_not_annotate.owl", "meta" : { "basicPropertyValues" : [ { "pred" : "http://www.w3.org/2002/07/owl#versionInfo", "val" : "2024-01-26" } ], "version" : "http://purl.obolibrary.org/obo/go/2024-01-26/subsets/gocheck_do_not_annotate.owl" }, "nodes" : [ { "id" : "http://purl.obolibrary.org/obo/BFO_0000050", "lbl" : "part of", "type" : "PROPERTY", "meta" : { "xrefs" : [ { "val" : "BFO:0000050" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "external" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand", "val" : "part_of" } ] } }, { "id" : "http://purl.obolibrary.org/obo/BFO_0000051", "lbl" : "has part", "type" : "PROPERTY", "meta" : { "xrefs" : [ { "val" : "BFO:0000051" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "external" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand", "val" : "has_part" } ] } }, { "id" : "http://purl.obolibrary.org/obo/BFO_0000062", "lbl" : "preceded by", "meta" : { "xrefs" : [ { "val" : "BFO:0000062" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "external" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand", "val" : "preceded_by" } ] } }, { "id" : "http://purl.obolibrary.org/obo/BFO_0000063", "lbl" : "precedes", "meta" : { "xrefs" : [ { "val" : "BFO:0000063" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "external" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand", "val" : "precedes" } ] } }, { "id" : "http://purl.obolibrary.org/obo/BFO_0000066", "lbl" : "occurs in", "type" : "PROPERTY", "meta" : { "xrefs" : [ { "val" : "BFO:0000066" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "external" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand", "val" : "occurs_in" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GOREL_0000040", "lbl" : "results in", "meta" : { "comments" : [ "This relation is currently used to connect two regulation processes p1 and p2, such that if r1 regulates p1 and r2 regulates p2, and r1 results_in r2 then the regulation of p1 is required for the regulation of p2. For an example of use, see GO:0035958 'regulation of glyoxylate cycle by regulation of transcription from RNA polymerase II promoter'. Note that a precise definition of this relation is under discussion. After it has been formalized it will be added to RO, where it will have a RO ID. Note that the existing identifier and label are subject to change." ], "xrefs" : [ { "val" : "GOREL:0000040" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "cjm" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2012-03-14T10:35:44Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "external" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand", "val" : "results_in" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GOREL_0001019", "lbl" : "results in division of", "meta" : { "comments" : [ "use occurs_in" ], "xrefs" : [ { "val" : "GOREL:0001019" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "external" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand", "val" : "results_in_division_of" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GOREL_0002003", "lbl" : "results in distribution of", "meta" : { "xrefs" : [ { "val" : "GOREL:0002003" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "external" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand", "val" : "results_in_distribution_of" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GOREL_0002004", "lbl" : "results in fission of", "meta" : { "xrefs" : [ { "val" : "GOREL:0002004" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "external" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand", "val" : "results_in_fission_of" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GOREL_0012006", "lbl" : "results in maintenance of", "meta" : { "xrefs" : [ { "val" : "GOREL:0012006" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "external" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#shorthand", "val" : "results_in_maintenance_of" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000027", "lbl" : "ribosomal large subunit assembly", "type" : "CLASS", "meta" : { "definition" : { "val" : "The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.", "xrefs" : [ "GOC:jl", "PMID:30467428" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "50S ribosomal subunit assembly", "xrefs" : [ "GOC:mah" ] }, { "pred" : "hasNarrowSynonym", "val" : "60S ribosomal subunit assembly", "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/23886" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000075", "lbl" : "cell cycle checkpoint signaling", "type" : "CLASS", "meta" : { "definition" : { "val" : "A signaling process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "This term should not be used in direct manual annotation as it should always be possible to minimally designate mitotic or meiotic checkpoint, and usually to additionally specify the checkpoint (i.e mitotic spindle assembly checkpoint, mitotic DNA damage checkpoint etc). Note also that the effector processes are not part of the checkpoint but are positively regulated by the checkpoint signaling and should not be annotated here." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell cycle checkpoint" }, { "pred" : "hasExactSynonym", "val" : "signal transduction involved in G2/M transition checkpoint" }, { "pred" : "hasExactSynonym", "val" : "signal transduction involved in cell cycle checkpoint" }, { "pred" : "hasNarrowSynonym", "val" : "G1/S checkpoint" }, { "pred" : "hasNarrowSynonym", "val" : "G1/S transition checkpoint" }, { "pred" : "hasNarrowSynonym", "val" : "G2/M checkpoint" }, { "pred" : "hasNarrowSynonym", "val" : "G2/M transition checkpoint" } ], "xrefs" : [ { "val" : "Wikipedia:Cell_cycle_checkpoint" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/20935" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0031576" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0071779" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0072395" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0072404" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0072407" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000079", "lbl" : "regulation of cyclin-dependent protein serine/threonine kinase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.", "xrefs" : [ "GOC:go_curators", "GOC:pr" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "regulation of cyclin-dependent protein kinase activity" }, { "pred" : "hasExactSynonym", "val" : "regulation of CDK activity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000080", "lbl" : "mitotic G1 phase", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by mitosis and the beginning of DNA synthesis.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "G1 phase of mitotic cell cycle" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000084", "lbl" : "mitotic S phase", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase, following G1, during which DNA synthesis takes place as part of a mitotic cell cycle.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "S phase of mitotic cell cycle" }, { "pred" : "hasExactSynonym", "val" : "S-phase of mitotic cell cycle" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000085", "lbl" : "mitotic G2 phase", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by mitosis.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "G2 phase of mitotic cell cycle" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000087", "lbl" : "mitotic M phase", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "M phase of mitotic cell cycle" }, { "pred" : "hasExactSynonym", "val" : "M-phase of mitotic cell cycle" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000088", "lbl" : "mitotic prophase", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase which is the first stage of M phase of mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000089", "lbl" : "mitotic metaphase", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase, following prophase, during which chromosomes become aligned on the equatorial plate of the cell as part of a mitotic cell cycle.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000090", "lbl" : "mitotic anaphase", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of a mitotic cell cycle.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000091", "lbl" : "mitotic anaphase A", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase during which the kinetochore microtubules shorten as chromosomes move toward the spindle poles as part of mitosis.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000092", "lbl" : "mitotic anaphase B", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase during which the polar microtubules elongate and the two poles of the spindle move farther apart as part of mitosis.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000093", "lbl" : "mitotic telophase", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase which follows anaphase during M phase of mitosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000236", "lbl" : "mitotic prometaphase", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase in higher eukaryotes which follows mitotic prophase and during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. Kinetochores mature on each centromere and attach to some of the spindle microtubules. Kinetochore microtubules begin the process of aligning chromosomes in one plane halfway between the poles.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/24374" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000237", "lbl" : "leptotene", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase which is the first stage of prophase I in meiosis, and during which the chromosomes first become visible.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "Wikipedia:Leptotene" }, { "val" : "Wikipedia:Meiosis#Leptotene" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000238", "lbl" : "zygotene", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase which follows leptotene during prophase I of meiosis, and during which each chromosome pairs with its homolog; the two become aligned and crossing over may occur.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "Wikipedia:Meiosis#Zygotene" }, { "val" : "Wikipedia:Zygotene" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000239", "lbl" : "pachytene", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase which follows zygotene during prophase I of meiosis, and during which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "Wikipedia:Meiosis#Pachytene" }, { "val" : "Wikipedia:Pachytene" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000240", "lbl" : "diplotene", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase which follows pachytene during prophase I of meiosis, during which the homologous chromosomes begin to separate and the synaptonemal complex dissolves.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "Wikipedia:Diplotene" }, { "val" : "Wikipedia:Meiosis#Diplotene" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000241", "lbl" : "diakinesis", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase which follows diplotene during prophase I of meiosis, the separation of homologous chromosomes is complete and crossing over has occurred.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "Wikipedia:Diakinesis" }, { "val" : "Wikipedia:Meiosis#Diakinesis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000279", "lbl" : "M phase", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "M-phase" } ], "xrefs" : [ { "val" : "Wikipedia:M_phase" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000413", "lbl" : "protein peptidyl-prolyl isomerization", "type" : "CLASS", "meta" : { "definition" : { "val" : "The modification of a protein by cis-trans isomerization of a proline residue.", "xrefs" : [ "GOC:krc", "PMID:16959570" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "protein proline isomerization" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0000422", "lbl" : "autophagy of mitochondrion", "type" : "CLASS", "meta" : { "definition" : { "val" : "The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions.", "xrefs" : [ "GOC:autophagy", "PMID:15798367", "PMID:19289147", "PMID:23065344" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "mitochondrion degradation" }, { "pred" : "hasBroadSynonym", "val" : "mitochondrion disassembly" }, { "pred" : "hasNarrowSynonym", "val" : "mitophagy" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/25541" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001816", "lbl" : "cytokine production", "type" : "CLASS", "meta" : { "definition" : { "val" : "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "cytokine biosynthetic process" }, { "pred" : "hasNarrowSynonym", "val" : "cytokine metabolic process" }, { "pred" : "hasNarrowSynonym", "val" : "cytokine secretion" }, { "pred" : "hasNarrowSynonym", "val" : "interferon production", "xrefs" : [ "GOC:add", "GOC:mah" ] }, { "pred" : "hasNarrowSynonym", "val" : "interferon secretion", "xrefs" : [ "GOC:add", "GOC:mah" ] }, { "pred" : "hasNarrowSynonym", "val" : "interleukin production", "xrefs" : [ "GOC:add", "GOC:mah", "http://wiki.geneontology.org/index.php/Why_isn%27t_interleukin_in_GO%3F" ] }, { "pred" : "hasNarrowSynonym", "val" : "interleukin secretion", "xrefs" : [ "GOC:add", "GOC:mah", "http://wiki.geneontology.org/index.php/Why_isn%27t_interleukin_in_GO%3F" ] } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/19116" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0042032" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0042089" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0042107" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0050663" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0001977", "lbl" : "renal system process involved in regulation of blood volume", "type" : "CLASS", "meta" : { "definition" : { "val" : "A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system.", "xrefs" : [ "GOC:dph", "GOC:tb", "ISBN:0721643949" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "renal blood volume control of blood pressure" }, { "pred" : "hasRelatedSynonym", "val" : "renal regulation of blood volume", "xrefs" : [ "GOC:dph", "GOC:tb" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002030", "lbl" : "inhibitory G protein-coupled receptor phosphorylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process that inhibits the signaling function of a G protein-coupled receptor by addition of a phosphate group to its third intracellular loop consensus site.", "xrefs" : [ "PMID:8396717" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "inhibitory G-protein coupled receptor phosphorylation" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_4751" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002032", "lbl" : "desensitization of G protein-coupled receptor signaling pathway by arrestin", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process that inhibits the signaling function of a G protein-coupled receptor by uncoupling the receptor from its downstream G proteins.", "xrefs" : [ "GOC:dph", "GOC:tb", "PMID:8396717" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "arrestin mediated desensitisation of G-protein coupled receptor protein signalling pathway" }, { "pred" : "hasExactSynonym", "val" : "arrestin mediated desensitization of G-protein coupled receptor protein signaling pathway", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, { "pred" : "hasExactSynonym", "val" : "arrestin-mediated desensitization of G-protein coupled receptor protein signaling pathway" }, { "pred" : "hasExactSynonym", "val" : "desensitization of G-protein coupled receptor protein signaling pathway by arrestin" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002084", "lbl" : "protein depalmitoylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The removal of palymitoyl groups from a lipoprotein.", "xrefs" : [ "GOC:hjd" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002367", "lbl" : "cytokine production involved in immune response", "type" : "CLASS", "meta" : { "definition" : { "val" : "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels.", "xrefs" : [ "GOC:add", "GO_REF:0000022", "ISBN:0781735149" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "cytokine biosynthetic process involved in immune response" }, { "pred" : "hasRelatedSynonym", "val" : "cytokine production during immune response", "xrefs" : [ "GOC:dph" ] }, { "pred" : "hasRelatedSynonym", "val" : "cytokine secretion during immune response", "xrefs" : [ "GOC:dph" ] }, { "pred" : "hasRelatedSynonym", "val" : "cytokine secretion involved in immune response" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0002374" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0002375" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002368", "lbl" : "B cell cytokine production", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that contributes to cytokine production by a B cell.", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "B lymphocyte cytokine production" }, { "pred" : "hasExactSynonym", "val" : "B-cell cytokine production" }, { "pred" : "hasExactSynonym", "val" : "B-lymphocyte cytokine production" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002369", "lbl" : "T cell cytokine production", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that contributes to cytokine production by a T cell.", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "T lymphocyte cytokine production" }, { "pred" : "hasExactSynonym", "val" : "T-cell cytokine production" }, { "pred" : "hasExactSynonym", "val" : "T-lymphocyte cytokine production" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002370", "lbl" : "natural killer cell cytokine production", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that contributes to cytokine production by a natural killer cell.", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "NK cell cytokine production" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002371", "lbl" : "dendritic cell cytokine production", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that contributes to cytokine production by a dendritic cell.", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002372", "lbl" : "myeloid dendritic cell cytokine production", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that contributes to cytokine production by a myeloid dendritic cell.", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002373", "lbl" : "plasmacytoid dendritic cell cytokine production", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that contributes to cytokine production by a plasmacytoid dendritic cell.", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002377", "lbl" : "immunoglobulin production", "type" : "CLASS", "meta" : { "definition" : { "val" : "The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "antibody production" }, { "pred" : "hasNarrowSynonym", "val" : "immunoglobulin biosynthetic process" }, { "pred" : "hasNarrowSynonym", "val" : "immunoglobulin secretion" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0002378" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0048305" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002381", "lbl" : "immunoglobulin production involved in immunoglobulin-mediated immune response", "type" : "CLASS", "meta" : { "definition" : { "val" : "The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels.", "xrefs" : [ "GOC:add", "ISBN:0781735149", "PMID:9185563" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "immunoglobulin production involved in immunoglobulin mediated immune response" }, { "pred" : "hasNarrowSynonym", "val" : "immunoglobulin biosynthetic process involved in immune response" }, { "pred" : "hasNarrowSynonym", "val" : "immunoglobulin secretion involved in immune response" }, { "pred" : "hasRelatedSynonym", "val" : "antibody production during immune response" }, { "pred" : "hasRelatedSynonym", "val" : "antibody secretion during immune response" }, { "pred" : "hasRelatedSynonym", "val" : "immunoglobulin production during immune response", "xrefs" : [ "GOC:dph" ] }, { "pred" : "hasRelatedSynonym", "val" : "immunoglobulin production involved in immune response", "xrefs" : [ "GOC:dph" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0002379" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0002380" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002426", "lbl" : "immunoglobulin production in mucosal tissue", "type" : "CLASS", "meta" : { "definition" : { "val" : "The synthesis and release of immunoglobulin in the mucosal tissue.", "xrefs" : [ "GOC:jal" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "antibody production in mucosal tissue" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002440", "lbl" : "production of molecular mediator of immune response", "type" : "CLASS", "meta" : { "definition" : { "val" : "The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels.", "xrefs" : [ "GOC:add", "GO_REF:0000022", "ISBN:0781735149" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "production of cellular mediator of immune response" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002534", "lbl" : "cytokine production involved in inflammatory response", "type" : "CLASS", "meta" : { "definition" : { "val" : "The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.", "xrefs" : [ "GOC:add", "ISBN:0781735149" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "cytokine production involved in acute inflammatory response" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002775", "lbl" : "antimicrobial peptide production", "type" : "CLASS", "meta" : { "definition" : { "val" : "The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.", "xrefs" : [ "GOC:add", "ISBN:0781735149", "PMID:11807545", "PMID:15638771" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002778", "lbl" : "antibacterial peptide production", "type" : "CLASS", "meta" : { "definition" : { "val" : "The synthesis or release of an antibacterial peptide during an immune response, resulting in an increase in intracellular or extracellular levels.", "xrefs" : [ "GOC:add", "ISBN:0781735149", "PMID:11807545", "PMID:15638771" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0002781", "lbl" : "antifungal peptide production", "type" : "CLASS", "meta" : { "definition" : { "val" : "The synthesis or release of an antifungal peptide during an immune response, resulting in an increase in intracellular or extracellular levels.", "xrefs" : [ "GOC:add", "ISBN:0781735149", "PMID:11807545", "PMID:15638771" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0003845", "lbl" : "11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD(P)+ = an 11-oxosteroid + NAD(P)H + H+.", "xrefs" : [ "PMID:15761036" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "beta-hydroxysteroid dehydrogenase" }, { "pred" : "hasRelatedSynonym", "val" : "11beta-hydroxy steroid dehydrogenase" }, { "pred" : "hasRelatedSynonym", "val" : "11beta-hydroxysteroid dehydrogenase" }, { "pred" : "hasRelatedSynonym", "val" : "corticosteroid 11-reductase" }, { "pred" : "hasRelatedSynonym", "val" : "corticosteroid 11beta-dehydrogenase" } ], "xrefs" : [ { "val" : "MetaCyc:11-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN" }, { "val" : "Reactome:R-HSA-194023" }, { "val" : "Wikipedia:11beta-hydroxysteroid_dehydrogenase" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/21915" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0004448", "lbl" : "isocitrate dehydrogenase [NAD(P)+] activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Catalysis of the reaction: isocitrate + NAD(P)+ = 2-oxoglutarate + CO2 + NAD(P)H.", "xrefs" : [ "GOC:curators" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "isocitrate dehydrogenase activity" }, { "pred" : "hasExactSynonym", "val" : "isocitric acid dehydrogenase activity" }, { "pred" : "hasExactSynonym", "val" : "isocitric dehydrogenase activity" }, { "pred" : "hasExactSynonym", "val" : "oxalosuccinate carboxylase activity" }, { "pred" : "hasExactSynonym", "val" : "oxalosuccinate decarboxylase activity" }, { "pred" : "hasExactSynonym", "val" : "oxalosuccinic decarboxylase activity" }, { "pred" : "hasRelatedSynonym", "val" : "IDH activity" }, { "pred" : "hasRelatedSynonym", "val" : "IDP activity" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/23235" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005215", "lbl" : "transporter activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.", "xrefs" : [ "GOC:ai", "GOC:dgf" ] }, "comments" : [ "Some transporters, such as certain members of the SLC family, are referred to as 'carriers'; however GO uses carrier with a different meaning: a carrier binds to and transports the substance (see GO:0140104 molecular carrier activity), whereas a transporter forms some pore that allows the passing of molecules." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "carrier" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0005478" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005488", "lbl" : "binding", "type" : "CLASS", "meta" : { "definition" : { "val" : "The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.", "xrefs" : [ "GOC:ceb", "GOC:mah", "ISBN:0198506732" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct, manual gene product annotation. Please choose a more specific child term, or request a new one if no suitable term is available. For ligands that bind to signal transducing receptors, consider the molecular function term 'receptor binding ; GO:0005102' and its children." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "ligand" } ], "xrefs" : [ { "val" : "Wikipedia:Binding_(molecular)" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005618", "lbl" : "cell wall", "type" : "CLASS", "meta" : { "definition" : { "val" : "The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.", "xrefs" : [ "GOC:giardia", "ISBN:0198547684", "PMID:15134259", "Wikipedia:Microbial_cyst" ] }, "comments" : [ "Not to be used for manual annotation. Please choose a more specific term: for bacteria, annotate to GO:0009274; peptidoglycan-based cell wall, for plants: annotate to GO:0009505 ; plant-type cell wall, for fungi: GO:0009277 ; fungal-type cell wall, and for archae, use GO:0030115 S-layer (see PMID:31214995)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "xrefs" : [ { "val" : "Wikipedia:Cell_wall" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/21669" }, { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_33208" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0005622", "lbl" : "intracellular anatomical structure", "type" : "CLASS", "meta" : { "definition" : { "val" : "A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm.", "xrefs" : [ "ISBN:0198506732" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "internal to cell" }, { "pred" : "hasExactSynonym", "val" : "intracellular" }, { "pred" : "hasExactSynonym", "val" : "protoplasm" }, { "pred" : "hasRelatedSynonym", "val" : "nucleocytoplasm", "xrefs" : [ "GOC:mah" ] }, { "pred" : "hasRelatedSynonym", "val" : "protoplast", "xrefs" : [ "GOC:mah" ] } ], "xrefs" : [ { "val" : "Wikipedia:Intracellular" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/17776" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006468", "lbl" : "protein phosphorylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process of introducing a phosphate group on to a protein.", "xrefs" : [ "GOC:hb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "protein amino acid phosphorylation", "xrefs" : [ "GOC:bf" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006469", "lbl" : "negative regulation of protein kinase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.", "xrefs" : [ "GOC:go_curators" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "down regulation of protein kinase activity" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of protein kinase activity" }, { "pred" : "hasExactSynonym", "val" : "downregulation of protein kinase activity" }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of protein kinase activity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006470", "lbl" : "protein dephosphorylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process of removing one or more phosphoric residues from a protein.", "xrefs" : [ "GOC:hb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "protein amino acid dephosphorylation", "xrefs" : [ "GOC:bf" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006473", "lbl" : "protein acetylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "protein amino acid acetylation", "xrefs" : [ "GOC:bf" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006474", "lbl" : "N-terminal protein amino acid acetylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The acetylation of the N-terminal amino acid of proteins.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "N(alpha)-terminal acetylation", "xrefs" : [ "PMID:11013267" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006475", "lbl" : "internal protein amino acid acetylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The addition of an acetyl group to a non-terminal amino acid in a protein.", "xrefs" : [ "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006476", "lbl" : "protein deacetylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "protein amino acid deacetylation", "xrefs" : [ "GOC:bf" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006477", "lbl" : "protein sulfation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The addition of a sulfate group as an ester to a protein amino acid.", "xrefs" : [ "GOC:curators" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "protein amino acid sulfation", "xrefs" : [ "GOC:bf" ] }, { "pred" : "hasExactSynonym", "val" : "protein amino acid sulphation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006478", "lbl" : "peptidyl-tyrosine sulfation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The sulfation of peptidyl-tyrosine residues to form peptidyl-O4'-sulfo-L-tyrosine.", "xrefs" : [ "RESID:AA0172" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "peptidyl-tyrosine sulphation" } ], "xrefs" : [ { "val" : "RESID:AA0172" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006479", "lbl" : "protein methylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "protein amino acid methylation", "xrefs" : [ "GOC:bf" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006480", "lbl" : "N-terminal protein amino acid methylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The methylation of the N-terminal amino acid of a protein.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006481", "lbl" : "C-terminal protein methylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The methylation of the C-terminal amino acid of a protein.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "C-terminal protein amino acid methylation", "xrefs" : [ "GOC:bf" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006482", "lbl" : "protein demethylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The removal of a methyl group, from a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.", "xrefs" : [ "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "protein amino acid demethylation", "xrefs" : [ "GOC:bf" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006497", "lbl" : "protein lipidation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The covalent attachment of lipid groups to an amino acid in a protein.", "xrefs" : [ "GOC:jl" ] }, "comments" : [ "For non-covalent interactions with a lipid, consider instead the term 'lipid binding ; GO:0008289' and its children." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "lipid:protein modification" }, { "pred" : "hasExactSynonym", "val" : "protein amino acid lipidation", "xrefs" : [ "GOC:bf" ] } ], "xrefs" : [ { "val" : "RESID:AA0059" }, { "val" : "RESID:AA0060" }, { "val" : "RESID:AA0077" }, { "val" : "RESID:AA0078" }, { "val" : "RESID:AA0079" }, { "val" : "RESID:AA0080" }, { "val" : "RESID:AA0102" }, { "val" : "RESID:AA0103" }, { "val" : "RESID:AA0104" }, { "val" : "RESID:AA0106" }, { "val" : "RESID:AA0107" }, { "val" : "RESID:AA0158" }, { "val" : "RESID:AA0159" }, { "val" : "RESID:AA0160" }, { "val" : "RESID:AA0161" }, { "val" : "RESID:AA0162" }, { "val" : "RESID:AA0163" }, { "val" : "RESID:AA0166" }, { "val" : "RESID:AA0223" }, { "val" : "RESID:AA0290" }, { "val" : "RESID:AA0307" }, { "val" : "RESID:AA0308" }, { "val" : "RESID:AA0309" }, { "val" : "RESID:AA0316" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0042050" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006498", "lbl" : "N-terminal protein lipidation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The covalent attachment of a lipid group to the amino terminus of a protein.", "xrefs" : [ "GOC:jl" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006499", "lbl" : "N-terminal protein myristoylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The covalent attachment of a myristoyl group to the N-terminal amino acid residue of a protein.", "xrefs" : [ "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006500", "lbl" : "N-terminal protein palmitoylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein.", "xrefs" : [ "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006501", "lbl" : "C-terminal protein lipidation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The covalent attachment of a lipid group to the carboxy-terminus of a protein.", "xrefs" : [ "GOC:jl" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006517", "lbl" : "protein deglycosylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The removal of sugar residues from a glycosylated protein.", "xrefs" : [ "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "glycoprotein deglycosylation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006807", "lbl" : "nitrogen compound metabolic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.", "xrefs" : [ "GOC:jl", "ISBN:0198506732" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "nitrogen compound metabolism" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/26424" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006810", "lbl" : "transport", "type" : "CLASS", "meta" : { "definition" : { "val" : "The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein.", "xrefs" : [ "GOC:dos", "GOC:dph", "GOC:jl", "GOC:mah" ] }, "comments" : [ "Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "single-organism transport" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/20292" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "jl" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2012-12-13T16:25:32Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0015457" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0015460" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0044765" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0006919", "lbl" : "activation of cysteine-type endopeptidase activity involved in apoptotic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process.", "xrefs" : [ "GOC:al", "GOC:dph", "GOC:jl", "GOC:mtg_apoptosis", "GOC:tb", "PMID:14744432", "PMID:18328827", "Wikipedia:Caspase" ] }, "comments" : [ "This term should be used when the annotation refers to a process that occurs in a context of apoptotic cell death. To annotate gene products involved in activation of cysteine-type endopeptidases in other cellular process (e.g., cell cycle arrest) that do not necessarily develop into an apoptotic process, please use the more general parent term GO:0097202. Examples of 'activation of cysteine-type endopeptidase activity involved in apoptotic process' are cytochrome c and Apaf1. When cytochrome c is released from mitochondria and forms a complex with Apaf1, they form a scaffolding platform in which the pro-caspase 9 is bound (the 'apoptosome'). The caspase is then cleaved and activated. Cytochrome c and Apaf1 are therefore involved in the conversion of the zymogen procaspase 9 to the active form of the caspase." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "caspase activation", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of caspase activity" }, { "pred" : "hasNarrowSynonym", "val" : "activation of metacaspase activity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007093", "lbl" : "mitotic cell cycle checkpoint signaling", "type" : "CLASS", "meta" : { "definition" : { "val" : "A signaling process that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "mitotic cell cycle checkpoint" }, { "pred" : "hasExactSynonym", "val" : "signal transduction involved in mitotic cell cycle checkpoint" }, { "pred" : "hasNarrowSynonym", "val" : "signal transduction involved in mitotic G2/M transition checkpoint" }, { "pred" : "hasNarrowSynonym", "val" : "signal transduction involved in mitotic cell cycle G1/S checkpoint" }, { "pred" : "hasRelatedSynonym", "val" : "mitotic checkpoint" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/20935" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0031575" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0071780" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0072413" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0072456" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0072474" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007128", "lbl" : "meiotic prophase I", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase which is the first stage of meiosis I and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007132", "lbl" : "meiotic metaphase I", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase, following prophase I, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis I.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/25408" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007133", "lbl" : "meiotic anaphase I", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis I.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/25408" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007134", "lbl" : "meiotic telophase I", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007136", "lbl" : "meiotic prophase II", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase which is the first stage of meiosis II and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007137", "lbl" : "meiotic metaphase II", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase, following prophase II, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis II.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/25408" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007138", "lbl" : "meiotic anaphase II", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis II.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/25408" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007139", "lbl" : "meiotic telophase II", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase which follows anaphase II of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007171", "lbl" : "activation of transmembrane receptor protein tyrosine kinase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity.", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "transmembrane receptor protein tyrosine kinase activation", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, { "pred" : "hasRelatedSynonym", "val" : "transmembrane receptor protein tyrosine kinase dimerization", "xrefs" : [ "GOC:dph", "GOC:mtg_lung" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007175", "lbl" : "negative regulation of epidermal growth factor-activated receptor activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops, prevents, or reduces the frequency, rate or extent of EGF-activated receptor activity.", "xrefs" : [ "GOC:go_curators" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "EGF receptor downregulation" }, { "pred" : "hasExactSynonym", "val" : "down regulation of epidermal growth factor receptor activity" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of epidermal growth factor receptor activity" }, { "pred" : "hasExactSynonym", "val" : "downregulation of epidermal growth factor receptor activity" }, { "pred" : "hasExactSynonym", "val" : "negative regulation of EGF receptor activity" }, { "pred" : "hasExactSynonym", "val" : "negative regulation of EGFR activity" }, { "pred" : "hasExactSynonym", "val" : "negative regulation of epidermal growth factor receptor activity", "xrefs" : [ "GOC:bf", "GOC:signaling" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of epidermal growth factor receptor activity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0007177" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007176", "lbl" : "regulation of epidermal growth factor-activated receptor activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of EGF-activated receptor activity.", "xrefs" : [ "GOC:dph", "GOC:go_curators" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "regulation of EGF receptor activity" }, { "pred" : "hasExactSynonym", "val" : "regulation of EGFR activity" }, { "pred" : "hasExactSynonym", "val" : "regulation of epidermal growth factor receptor activity", "xrefs" : [ "GOC:bf", "GOC:signaling" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007190", "lbl" : "activation of adenylate cyclase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that initiates the activity of the inactive enzyme adenylate cyclase.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "adenylate cyclase activation", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, { "pred" : "hasExactSynonym", "val" : "adenylyl cyclase activation" }, { "pred" : "hasRelatedSynonym", "val" : "adenylate cyclase activator" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007194", "lbl" : "negative regulation of adenylate cyclase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity.", "xrefs" : [ "GOC:go_curators" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "down regulation of adenylate cyclase activity" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of adenylate cyclase activity" }, { "pred" : "hasExactSynonym", "val" : "downregulation of adenylate cyclase activity" }, { "pred" : "hasExactSynonym", "val" : "negative regulation of adenylyl cyclase activity" }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of adenylate cyclase activity" }, { "pred" : "hasRelatedSynonym", "val" : "adenylate cyclase inhibitor" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007202", "lbl" : "activation of phospholipase C activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "The initiation of the activity of the inactive enzyme phospolipase C as the result of The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand.", "xrefs" : [ "GOC:dph", "GOC:mah", "GOC:tb", "PMID:8280098" ] }, "comments" : [ "Note that this term refers to a signaling pathway, and should not be confused with function terms such as 'phospholipase activator activity ; GO:0016004'." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "phospholipase C activation", "xrefs" : [ "GOC:dph", "GOC:tb" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007250", "lbl" : "activation of NF-kappaB-inducing kinase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues.", "xrefs" : [ "GOC:jl", "PMID:12773372" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "positive regulation of NF-kappaB-inducing kinase activity" }, { "pred" : "hasExactSynonym", "val" : "activation of NIK activity", "xrefs" : [ "GOC:bf" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007252", "lbl" : "I-kappaB phosphorylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.", "xrefs" : [ "GOC:bf", "GOC:jl", "PMID:21772278", "PMID:7594468" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "IKB phosphorylation", "xrefs" : [ "GOC:bf" ] }, { "pred" : "hasExactSynonym", "val" : "IkappaB phosphorylation", "xrefs" : [ "GOC:bf" ] }, { "pred" : "hasExactSynonym", "val" : "inhibitor of NF-kappaB phosphorylation", "xrefs" : [ "GOC:bf" ] }, { "pred" : "hasExactSynonym", "val" : "inhibitor of kappaB phosphorylation", "xrefs" : [ "GOC:bf" ] } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_4751" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007253", "lbl" : "cytoplasmic sequestering of NF-kappaB", "type" : "CLASS", "meta" : { "definition" : { "val" : "The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus.", "xrefs" : [ "GOC:jl" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cytoplasmic NF-kappaB retention" }, { "pred" : "hasExactSynonym", "val" : "cytoplasmic NF-kappaB sequestration" }, { "pred" : "hasExactSynonym", "val" : "cytoplasmic NF-kappaB storage" }, { "pred" : "hasExactSynonym", "val" : "cytoplasmic retention of NF-kappaB" }, { "pred" : "hasExactSynonym", "val" : "cytoplasmic sequestration of NF-kappaB" }, { "pred" : "hasExactSynonym", "val" : "cytoplasmic storage of NF-kappaB" }, { "pred" : "hasExactSynonym", "val" : "maintenance of NF-kappaB location in cytoplasm", "xrefs" : [ "GOC:dph", "GOC:tb" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007258", "lbl" : "JUN phosphorylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process of introducing a phosphate group into a JUN protein.", "xrefs" : [ "GOC:jl" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/RO_0002161", "val" : "http://purl.obolibrary.org/obo/NCBITaxon_4895" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007260", "lbl" : "tyrosine phosphorylation of STAT protein", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process of introducing a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.", "xrefs" : [ "GOC:jl", "PMID:10918594" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "tyrosine phosphorylation of Stat1 protein" }, { "pred" : "hasNarrowSynonym", "val" : "tyrosine phosphorylation of Stat2 protein" }, { "pred" : "hasNarrowSynonym", "val" : "tyrosine phosphorylation of Stat3 protein" }, { "pred" : "hasNarrowSynonym", "val" : "tyrosine phosphorylation of Stat4 protein" }, { "pred" : "hasNarrowSynonym", "val" : "tyrosine phosphorylation of Stat5 protein" }, { "pred" : "hasNarrowSynonym", "val" : "tyrosine phosphorylation of Stat6 protein" }, { "pred" : "hasNarrowSynonym", "val" : "tyrosine phosphorylation of Stat7 protein" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0042502" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0042503" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0042504" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0042505" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0042506" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0042507" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0042508" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007275", "lbl" : "multicellular organism development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).", "xrefs" : [ "GOC:dph", "GOC:ems", "GOC:isa_complete", "GOC:tb" ] }, "comments" : [ "Note that this term was 'developmental process'." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/21234" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0007588", "lbl" : "excretion", "type" : "CLASS", "meta" : { "definition" : { "val" : "The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.", "xrefs" : [ "ISBN:0192801023" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "xrefs" : [ { "val" : "Wikipedia:Excretion" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/22368" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0008134", "lbl" : "transcription factor binding", "type" : "CLASS", "meta" : { "definition" : { "val" : "Binding to a transcription factor, a protein required to initiate or regulate transcription.", "xrefs" : [ "ISBN:0198506732" ] }, "comments" : [ "Note that this term should not be used for direct annotation. Please consier one of the more specific descendants, GO:0140297 ; DNA-binding transcription factor binding, GO:0140296 ; general transcription initiation factor binding or GO:0001221 ; transcription coregulator binding." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_metagenomics", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "TF binding" }, { "pred" : "hasRelatedSynonym", "val" : "transcription regulator binding" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/19354" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0008213", "lbl" : "protein alkylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The addition of an alkyl group to a protein amino acid. Alkyl groups are derived from alkanes by removal of one hydrogen atom.", "xrefs" : [ "GOC:ma" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "protein amino acid alkylation", "xrefs" : [ "GOC:bf" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0008214", "lbl" : "protein dealkylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The removal of an alkyl group from a protein amino acid. Alkyl groups are derived from alkanes by removal of one hydrogen atom.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "protein amino acid dealkylation", "xrefs" : [ "GOC:bf" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0008219", "lbl" : "cell death", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).", "xrefs" : [ "GOC:mah", "GOC:mtg_apoptosis", "PMID:25236395" ] }, "comments" : [ "This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "accidental cell death" }, { "pred" : "hasRelatedSynonym", "val" : "necrosis" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/24680" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0008612", "lbl" : "peptidyl-lysine modification to peptidyl-hypusine", "type" : "CLASS", "meta" : { "definition" : { "val" : "The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.", "xrefs" : [ "GOC:ma", "ISBN:0198547684", "RESID:AA0116" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "hypusine anabolism" }, { "pred" : "hasExactSynonym", "val" : "hypusine anabolism from peptidyl-lysine" }, { "pred" : "hasExactSynonym", "val" : "hypusine biosynthesis" }, { "pred" : "hasExactSynonym", "val" : "hypusine biosynthetic process" }, { "pred" : "hasExactSynonym", "val" : "hypusine biosynthetic process from peptidyl-lysine" }, { "pred" : "hasExactSynonym", "val" : "hypusine formation" }, { "pred" : "hasExactSynonym", "val" : "hypusine formation from peptidyl-lysine" }, { "pred" : "hasExactSynonym", "val" : "hypusine synthesis" }, { "pred" : "hasExactSynonym", "val" : "hypusine synthesis from peptidyl-lysine" }, { "pred" : "hasExactSynonym", "val" : "hypusinylation" }, { "pred" : "hasExactSynonym", "val" : "protein hypusination" } ], "xrefs" : [ { "val" : "RESID:AA0116" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0046515" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0008635", "lbl" : "activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process and is mediated by cytochrome c.", "xrefs" : [ "GOC:dph", "GOC:jl", "GOC:mtg_apoptosis", "GOC:tb", "PMID:14744432", "Wikipedia:Caspase" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "caspase activation via cytochrome c", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of caspase activity by cytochrome c" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0008937", "lbl" : "ferredoxin-NAD(P) reductase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Catalysis of the reaction: reduced ferredoxin + NAD(P)+ = oxidized ferredoxin + NAD(P)H + H+.", "xrefs" : [ "GOC:curators" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "ferredoxin reductase activity" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/21649" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0009249", "lbl" : "protein lipoylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The lipoylation of peptidyl-lysine to form peptidyl-N6-lipoyl-L-lysine.", "xrefs" : [ "RESID:AA0118" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "peptidyl-lysine lipoylation" }, { "pred" : "hasExactSynonym", "val" : "protein-lipoic acid cofactor linkage" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0018055" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0009987", "lbl" : "cellular process", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.", "xrefs" : [ "GOC:go_curators", "GOC:isa_complete" ] }, "comments" : [ "This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cell physiology" }, { "pred" : "hasExactSynonym", "val" : "cellular physiological process" }, { "pred" : "hasNarrowSynonym", "val" : "cell growth and/or maintenance" }, { "pred" : "hasRelatedSynonym", "val" : "single-organism cellular process" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "jl" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2012-12-11T16:56:55Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0008151" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0044763" }, { "pred" : 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Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0010924", "lbl" : "regulation of inositol-polyphosphate 5-phosphatase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0010925", "lbl" : "positive regulation of inositol-polyphosphate 5-phosphatase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that increases the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0010934", "lbl" : "macrophage cytokine production", "type" : "CLASS", "meta" : { "definition" : { "val" : "The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:rl", "GOC:tb" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0010950", "lbl" : "positive regulation of endopeptidase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that increases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-04-27T11:45:39Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0010951", "lbl" : "negative regulation of endopeptidase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_chembl" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-04-27T11:47:01Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0010952", "lbl" : "positive regulation of peptidase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-04-27T11:54:32Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0010956", "lbl" : "negative regulation of calcidiol 1-monooxygenase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that decreases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-05-06T11:21:34Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0010979", "lbl" : "regulation of vitamin D 24-hydroxylase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-06-01T11:44:54Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0010980", "lbl" : "positive regulation of vitamin D 24-hydroxylase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that increases the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-06-01T11:47:19Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0010998", "lbl" : "regulation of translational initiation by eIF2 alpha phosphorylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:hjd", "GOC:tb" ] }, "comments" : [ "Consider also annotating to 'eukaryotic translation initiation factor 2alpha kinase activity ; GO:0004694'." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "eIF2 alpha phosphorylation in response to stress", "xrefs" : [ "GOC:bf" ] }, { "pred" : "hasExactSynonym", "val" : "regulation of translational initiation by eIF2 alpha phosphorylation in response to stress", "xrefs" : [ "GOC:bf" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-06-10T11:27:47Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0015013", "lbl" : "heparan sulfate proteoglycan biosynthetic process, linkage to polypeptide", "type" : "CLASS", "meta" : { "definition" : { "val" : "The polymerization of one or more heparan sulfate chains via a xylose link onto serine residues in the core protein of a proteoglycan.", "xrefs" : [ "ISBN:0815316194" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "heparan sulfate proteoglycan anabolism, linkage to polypeptide" }, { "pred" : "hasExactSynonym", "val" : "heparan sulfate proteoglycan formation, linkage to polypeptide" }, { "pred" : "hasExactSynonym", "val" : "heparan sulfate proteoglycan synthesis, linkage to polypeptide" }, { "pred" : "hasExactSynonym", "val" : "heparan sulphate proteoglycan biosynthesis, linkage to polypeptide" }, { "pred" : "hasExactSynonym", "val" : "heparan sulphate proteoglycan biosynthetic process, linkage to polypeptide" }, { "pred" : "hasRelatedSynonym", "val" : "heparin proteoglycan biosynthetic process, linkage to polypeptide" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0015318", "lbl" : "inorganic molecular entity transmembrane transporter activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon.", "xrefs" : [ "GOC:mtg_transport", "ISBN:0815340729" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "inorganic solute uptake transmembrane transporter activity" }, { "pred" : "hasExactSynonym", "val" : "inorganic uptake permease activity" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/14372" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0016049", "lbl" : "cell growth", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_pir", "http://purl.obolibrary.org/obo/go#goslim_plant" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cellular growth" }, { "pred" : "hasExactSynonym", "val" : "growth of cell" }, { "pred" : "hasRelatedSynonym", "val" : "cell expansion" }, { "pred" : "hasRelatedSynonym", "val" : "metabolic process resulting in cell growth" }, { "pred" : "hasRelatedSynonym", "val" : "metabolism resulting in cell growth" }, { "pred" : "hasRelatedSynonym", "val" : "non-developmental cell growth", "xrefs" : [ "GOC:mah" ] }, { "pred" : "hasRelatedSynonym", "val" : "non-developmental growth of a unicellular organism", "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0048591" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0016061", "lbl" : "regulation of light-activated channel activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of light-activated channel activity.", "xrefs" : [ "GOC:go_curators" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0016267", "lbl" : "O-glycan processing, core 1", "type" : "CLASS", "meta" : { "definition" : { "val" : "The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 1 O-glycan structure, Gal-beta-(1->3)-GalNAc.", "xrefs" : [ "GOC:mah", "GOC:pr", "PMID:10580130" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0016268", "lbl" : "O-glycan processing, core 2", "type" : "CLASS", "meta" : { "definition" : { "val" : "The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 2 O-glycan structure, GlcNAc-beta-(1->6)[Gal-beta-(1->3)]-GalNAc.", "xrefs" : [ "GOC:mah", "GOC:pr", "PMID:10580130" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0016269", "lbl" : "O-glycan processing, core 3", "type" : "CLASS", "meta" : { "definition" : { "val" : "The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 3 O-glycan structure, GlcNAc-beta-(1->3)-GalNAc.", "xrefs" : [ "GOC:mah", "GOC:pr", "PMID:10580130" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0016270", "lbl" : "O-glycan processing, core 4", "type" : "CLASS", "meta" : { "definition" : { "val" : "The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 4 O-glycan structure, GlcNAc-beta-(1->6)[GalNAc-beta-(1->3)]-GalNAc.", "xrefs" : [ "GOC:mah", "GOC:pr", "PMID:10580130" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0016579", "lbl" : "protein deubiquitination", "type" : "CLASS", "meta" : { "definition" : { "val" : "The removal of one or more ubiquitin groups from a protein.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "deubiquitination" }, { "pred" : "hasExactSynonym", "val" : "protein deubiquitinylation" }, { "pred" : "hasExactSynonym", "val" : "protein deubiquitylation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0006514" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0016598", "lbl" : "protein arginylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The conjugation of arginine to the N-terminal aspartate or glutamate of a protein; required for the degradation of the protein via the ubiquitin pathway.", "xrefs" : [ "PMID:17896865" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "protein amino acid arginylation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0019130" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0017003", "lbl" : "protein-heme linkage", "type" : "CLASS", "meta" : { "definition" : { "val" : "The covalent linkage of heme and a protein.", "xrefs" : [ "GOC:ma" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "protein-haem 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"biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0017008", "lbl" : "protein-phycobiliviolin linkage", "type" : "CLASS", "meta" : { "definition" : { "val" : "The linkage of the chromophore phycobiliviolin to phycoerythrocyanin.", "xrefs" : [ "RESID:AA0258" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "RESID:AA0258" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0017009", "lbl" : "protein-phycocyanobilin linkage", "type" : "CLASS", "meta" : { "definition" : { "val" : "The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin.", "xrefs" : [ "RESID:AA0131" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "RESID:AA0131" } ], "basicPropertyValues" : [ { "pred" : 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"peptidyl-S-12-hydroxyfarnesyl-L-cysteine synthesis from peptidyl-cysteine" } ], "xrefs" : [ { "val" : "RESID:AA0103" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0018228", "lbl" : "peptidyl-S-geranylgeranyl-L-cysteine biosynthetic process from peptidyl-cysteine", "type" : "CLASS", "meta" : { "definition" : { "val" : "The modification of peptidyl-cysteine to form peptidyl-S-geranylgeranylcysteine; formation of S-geranylgeranyl-L-cysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CAAX motif and methyl esterification of the geranylgeranylated cysteine; methyl esterification but not cleavage occurs for the CXC motif. For the type II geranylgeranyltransferase the residue may be found at the first and final positions in the sequence motif C-X-C* or at the final position in the sequence motif C-C*. These motifs are necessary but not sufficient for modification.", "xrefs" : [ "RESID:AA0104" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "peptidyl-S-geranylgeranyl-L-cysteine anabolism from peptidyl-cysteine" }, { "pred" : "hasExactSynonym", "val" : "peptidyl-S-geranylgeranyl-L-cysteine formation from peptidyl-cysteine" }, { "pred" : "hasExactSynonym", "val" : "peptidyl-S-geranylgeranyl-L-cysteine synthesis from peptidyl-cysteine" } ], "xrefs" : [ { "val" : "RESID:AA0104" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0018230", "lbl" : "peptidyl-L-cysteine S-palmitoylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form 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coupled with the formation of 5-imidazolinone by the two neighboring residues, produces an 4-methylidene-imidazole-5-one active site of some amino acid ammonia-lyases; the 4-methylidene-imidazole-5-one, is formed autocatalytically by cyclization and dehydration of the sequence ASG.", "xrefs" : [ "RESID:AA0181" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "peptidyl-dehydroalanine anabolism from peptidyl-tyrosine or peptidyl-serine" }, { "pred" : "hasExactSynonym", "val" : "peptidyl-dehydroalanine formation from peptidyl-tyrosine or peptidyl-serine" }, { "pred" : "hasExactSynonym", "val" : "peptidyl-dehydroalanine synthesis from peptidyl-tyrosine or peptidyl-serine" } ], "xrefs" : [ { "val" : "RESID:AA0181" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : 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"http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0042075", "lbl" : "nickel incorporation into nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide", "type" : "CLASS", "meta" : { "definition" : { "val" : "The incorporation of nickel into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase.", "xrefs" : [ "RESID:AA0310" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "nickel incorporation into nickel-iron-sulphur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulphide" } ], "xrefs" : [ { "val" : "RESID:AA0310" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0042077", "lbl" : "protein phosphate-linked glycosylation via serine", "type" : "CLASS", "meta" : { "definition" : { "val" : "The glycosylation of peptidyl-serine through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues.", "xrefs" : [ "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "protein amino acid phosphate-linked glycosylation via serine", "xrefs" : [ "GOC:bf" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0042082", "lbl" : "GSI anchor biosynthetic process", "type" : "CLASS", "meta" : { "definition" : { "val" : "The chemical reactions and pathways resulting in the formation of a glycosylsphingolipidinositol (GSI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The sphingolipid group is linked, via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via a ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GSI anchors have variants on this canonical linkage.", "xrefs" : [ "GOC:go_curators", "GOC:jsg" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "GPI/GSI anchor biosynthesis" }, { "pred" : "hasBroadSynonym", "val" : "GPI/GSI anchor biosynthetic process" }, { "pred" : "hasExactSynonym", "val" : "GSI anchor anabolism" }, { "pred" : "hasExactSynonym", "val" : "GSI anchor biosynthesis" }, { "pred" : "hasExactSynonym", "val" : "GSI anchor formation" }, { "pred" : "hasExactSynonym", "val" : "GSI anchor synthesis" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0042258", "lbl" : "molybdenum incorporation via L-serinyl molybdopterin guanine dinucleotide", "type" : "CLASS", "meta" : { "definition" : { "val" : "The incorporation of molybdenum into a protein via L-serinyl molybdopterin guanine dinucleotide.", "xrefs" : [ "PDB:1EU1", "PMID:8658132", "RESID:AA0319" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "RESID:AA0319" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0042264", "lbl" : "peptidyl-aspartic acid hydroxylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The hydroxylation of peptidyl-aspartic acid to form peptidyl-hydroxyaspartic acid.", "xrefs" : [ "GOC:mah" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "peptidyl-aspartic acid/asparagine hydroxylation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0042501", "lbl" : "serine phosphorylation of STAT protein", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process of introducing a phosphate group to a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.", "xrefs" : [ "GOC:jl", "PMID:10918594" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "serine phosphorylation of STAT3 protein" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0033136" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0042637", "lbl" : "catagen", "type" : "CLASS", "meta" : { "definition" : { "val" : "The regression phase of the hair cycle during which cell proliferation ceases, the hair follicle shortens, and an anchored club hair is produced.", "xrefs" : [ "PMID:12535193" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "hair regression" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0042638", "lbl" : "exogen", "type" : "CLASS", "meta" : { "definition" : { "val" : "The shedding phase of the hair cycle.", "xrefs" : [ "PMID:12230507" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "hair shedding" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0042639", "lbl" : "telogen", "type" : "CLASS", "meta" : { "definition" : { "val" : "The resting phase of hair cycle.", "xrefs" : [ "PMID:12230507" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "hair resting phase" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0042640", "lbl" : "anagen", "type" : "CLASS", "meta" : { "definition" : { "val" : "The growth phase of the hair cycle. Lasts, for example, about 3 to 6 years for human scalp hair.", "xrefs" : [ "PMID:12230507" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "hair growth" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0042696", "lbl" : "menarche", "type" : "CLASS", "meta" : { "definition" : { "val" : "The beginning of the menstrual cycle; the first menstrual cycle in an individual.", "xrefs" : [ "GOC:curators", "PMID:16311040" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "Wikipedia:Menarche" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0042697", "lbl" : "menopause", "type" : "CLASS", "meta" : { "definition" : { "val" : "Cessation of menstruation, occurring in (e.g.) the human female usually around the age of 50.", "xrefs" : [ "GOC:curators", "PMID:18495681" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "Wikipedia:Menopause" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0042703", "lbl" : "menstruation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cyclic, physiologic discharge through the vagina of blood and endometrial tissues from the nonpregnant uterus.", "xrefs" : [ "GOC:curators", "PMID:8693059" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "Wikipedia:Menstruation" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0042710", "lbl" : "biofilm formation", "type" : "CLASS", "meta" : { "definition" : { "val" : "A process in which planktonically growing microorganisms grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.", "xrefs" : [ "GOC:di", "PMID:11932229" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate", "http://purl.obolibrary.org/obo/go#goslim_candida", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/17727" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0042902", "lbl" : "peptidoglycan-protein cross-linking via L-threonyl-pentaglycyl-murein", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process of linking a protein to peptidoglycan via a carboxy terminal threonine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan.", "xrefs" : [ "RESID:AA0345" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "RESID:AA0345" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0042976", "lbl" : "activation of Janus kinase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.", "xrefs" : [ "GOC:jl", "PMID:12479803" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "activation of JAK protein", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, { "pred" : "hasExactSynonym", "val" : "activation of JAK protein by tyrosine phosphorylation" }, { "pred" : "hasExactSynonym", "val" : "positive regulation of JAK protein activity by tyrosine phosphorylation" }, { "pred" : "hasExactSynonym", "val" : "tyrosine phosphorylation of JAK protein" }, { "pred" : "hasNarrowSynonym", "val" : "activation of JAK1 kinase activity" }, { "pred" : "hasNarrowSynonym", "val" : "activation of JAK1 protein", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of JAK2 kinase activity" }, { "pred" : "hasNarrowSynonym", "val" : "activation of JAK2 protein", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, { "pred" : "hasNarrowSynonym", "val" : "tyrosine phosphorylation of JAK1 protein", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, { "pred" : "hasNarrowSynonym", "val" : "tyrosine phosphorylation of JAK2 protein" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0010531" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0042977" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0042994", "lbl" : "cytoplasmic sequestering of transcription factor", "type" : "CLASS", "meta" : { "definition" : { "val" : "The selective interaction of a transcription factor with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus.", "xrefs" : [ "GOC:jl" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cytoplasmic retention of transcription factor" }, { "pred" : "hasExactSynonym", "val" : "cytoplasmic sequestration of transcription factor" }, { "pred" : "hasExactSynonym", "val" : "cytoplasmic storage of transcription factor" }, { "pred" : "hasExactSynonym", "val" : "maintenance of transcription factor protein location in cytoplasm", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, { "pred" : "hasExactSynonym", "val" : "retention of transcription factor in cytoplasm" }, { "pred" : "hasExactSynonym", "val" : "sequestering of transcription 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"hasExactSynonym", "val" : "up regulation of enzyme activity" }, { "pred" : "hasExactSynonym", "val" : "up-regulation of enzyme activity" }, { "pred" : "hasExactSynonym", "val" : "upregulation of enzyme activity" }, { "pred" : "hasNarrowSynonym", "val" : "activation of enzyme activity" }, { "pred" : "hasNarrowSynonym", "val" : "activation of metalloenzyme activity" }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of metalloenzyme activity" }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of enzyme activity" }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of metalloenzyme activity" }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of metalloenzyme activity" }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of metalloenzyme activity" }, { "pred" : "hasNarrowSynonym", "val" : "upregulation of metalloenzyme activity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0048554" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0043086", "lbl" : "negative regulation of catalytic activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops or reduces the activity of an enzyme.", "xrefs" : [ "GOC:ebc", "GOC:jl", "GOC:tb", "GOC:vw" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "down regulation of enzyme activity" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of enzyme activity" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of metalloenzyme activity" }, { "pred" : "hasExactSynonym", "val" : "downregulation of enzyme activity" }, { "pred" : "hasExactSynonym", "val" : "negative regulation of enzyme activity", "xrefs" : [ "GOC:tb" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of metalloenzyme activity" }, { 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] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051217", "lbl" : "molybdenum incorporation via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide)", "type" : "CLASS", "meta" : { "definition" : { "val" : "The incorporation of molybdenum into a protein via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide).", "xrefs" : [ "PDB:1Q16", "PMID:12910261", "RESID:AA0375" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "RESID:AA0375" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051218", "lbl" : "tungsten incorporation via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide)", "type" : "CLASS", "meta" : { "definition" : { "val" : "The incorporation of tungsten into a protein via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide).", "xrefs" : [ "PDB:1HOH", "PMID:12220497", "RESID:AA0376" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "RESID:AA0376" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051221", "lbl" : "tungsten incorporation into metallo-sulfur cluster", "type" : "CLASS", "meta" : { "definition" : { "val" : "The incorporation of tungsten into a metallo-sulfur cluster.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "tungsten incorporation into metallo-sulphur cluster" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051234", "lbl" : "establishment of localization", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.", "xrefs" : [ "GOC:ai", "GOC:dos" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_agr", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_mouse", "http://purl.obolibrary.org/obo/go#goslim_pir" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "establishment of localisation", "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/24200" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051318", "lbl" : "G1 phase", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle 'gap' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "Wikipedia:G1_phase" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051319", "lbl" : "G2 phase", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis).", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "Wikipedia:G2_phase" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051320", "lbl" : "S phase", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase, following G1, during which DNA synthesis takes place.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "S-phase" } ], "xrefs" : [ { "val" : "Wikipedia:S_phase" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051322", "lbl" : "anaphase", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase, following metaphase, during which the chromosomes separate and migrate towards the poles of the spindle.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "Wikipedia:Anaphase" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051323", "lbl" : "metaphase", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase, following prophase or prometaphase in higher eukaryotes, during which chromosomes become aligned on the equatorial plate of the cell.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "Wikipedia:Metaphase" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051324", "lbl" : "prophase", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase which is the first stage of M phase of meiosis and mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "Wikipedia:Prophase" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051325", "lbl" : "interphase", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "resting phase" }, { "pred" : "hasExactSynonym", "val" : "karyostasis" } ], "xrefs" : [ { "val" : "Wikipedia:Interphase" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051326", "lbl" : "telophase", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "note that this term should not be used for direct annotation. if you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic s-phase). to capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "Wikipedia:Telophase" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051327", "lbl" : "meiotic M phase", "type" : "CLASS", "meta" : { "definition" : { "val" : "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "M phase of meiotic cell cycle" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051328", "lbl" : "meiotic interphase", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. Meiotic cells have an interphase after each meiotic division, but only interphase I involves replication of the cell's DNA.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "interphase of meiotic cell cycle" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051329", "lbl" : "mitotic interphase", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "interphase of mitotic cell cycle" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051330", "lbl" : "meiotic G1 phase", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by meiosis and the beginning of DNA synthesis.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "G1 phase of meiotic cell cycle" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051331", "lbl" : "meiotic G2 phase", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by meiosis.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "G2 phase of meiotic cell cycle" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051332", "lbl" : "meiotic S phase", "type" : "CLASS", "meta" : { "definition" : { "val" : "The cell cycle phase, following G1, during which DNA synthesis takes place as part of a meiotic cell cycle.", "xrefs" : [ "GOC:mtg_cell_cycle" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "S phase of meiotic cell cycle" }, { "pred" : "hasExactSynonym", "val" : "S-phase of meiotic cell cycle" }, { "pred" : "hasExactSynonym", "val" : "premeiotic S-phase" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051336", "lbl" : "regulation of hydrolase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "hydrolase regulator" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051338", "lbl" : "regulation of transferase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.", "xrefs" : [ "GOC:ai" ] }, "comments" : [ "This term is useful for grouping, but is too general for manual annotation. Please use a child term instead." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "transferase regulator" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051339", "lbl" : "regulation of lyase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "lyase regulator" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051340", "lbl" : "regulation of ligase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "ligase regulator" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051341", "lbl" : "regulation of oxidoreductase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "oxidoreductase regulator" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051342", "lbl" : "regulation of cyclic-nucleotide phosphodiesterase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.", "xrefs" : [ "EC:3.1.4.17", "GOC:ai", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "3',5' cyclic nucleotide phosphodiesterase regulator" }, { "pred" : "hasExactSynonym", "val" : "regulation of 3',5' cyclic nucleotide phosphodiesterase activity" }, { "pred" : "hasExactSynonym", "val" : "regulation of cyclic nucleotide phosphodiesterase activity", "xrefs" : [ "GOC:tb" ] }, { "pred" : "hasNarrowSynonym", "val" : "3',5'-cyclic-AMP phosphodiesterase regulator" }, { "pred" : "hasNarrowSynonym", "val" : "cAMP phosphodiesterase regulator" }, { "pred" : "hasNarrowSynonym", "val" : "regulation of 3',5'-cyclic-AMP phosphodiesterase activity" }, { "pred" : "hasNarrowSynonym", "val" : "regulation of cAMP phosphodiesterase activity" }, { "pred" : "hasNarrowSynonym", "val" : "regulation of cGMP phosphodiesterase activity", "xrefs" : [ "GOC:tb" ] }, { "pred" : "hasRelatedSynonym", "val" : "phosphodiesterase regulator" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051343", "lbl" : "positive regulation of cyclic-nucleotide phosphodiesterase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.", "xrefs" : [ "GOC:ai", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "3',5' cyclic nucleotide phosphodiesterase activator" }, { "pred" : "hasExactSynonym", "val" : "positive regulation of 3',5' cyclic nucleotide phosphodiesterase activity" }, { "pred" : "hasExactSynonym", "val" : "positive regulation of cyclic nucleotide phosphodiesterase activity", "xrefs" : [ "GOC:tb" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of cyclic nucleotide phosphodiesterase activity" }, { "pred" : "hasExactSynonym", "val" : "up-regulation of cyclic nucleotide phosphodiesterase activity" }, { "pred" : "hasExactSynonym", "val" : "upregulation of cyclic nucleotide phosphodiesterase activity" }, { "pred" : "hasNarrowSynonym", "val" : "3',5'-cyclic-AMP phosphodiesterase activator" }, { "pred" : "hasNarrowSynonym", "val" : "activation of cyclic nucleotide phosphodiesterase activity" }, { "pred" : "hasNarrowSynonym", "val" : "cAMP phosphodiesterase activator" }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of 3',5'-cyclic-AMP phosphodiesterase activity" }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of cAMP phosphodiesterase activity" }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of cGMP phosphodiesterase activity", "xrefs" : [ "GOC:tb" ] }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of cyclic nucleotide phosphodiesterase activity" }, { "pred" : "hasRelatedSynonym", "val" : "phosphodiesterase activator" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051344", "lbl" : "negative regulation of cyclic-nucleotide phosphodiesterase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops or reduces the rate of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.", "xrefs" : [ "GOC:ai", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "3',5' cyclic nucleotide phosphodiesterase inhibitor" }, { "pred" : "hasExactSynonym", "val" : "down regulation of cyclic nucleotide phosphodiesterase activity" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of cyclic nucleotide phosphodiesterase activity" }, { "pred" : "hasExactSynonym", "val" : "downregulation of cyclic nucleotide phosphodiesterase activity" }, { "pred" : "hasExactSynonym", "val" : "negative regulation of 3',5' cyclic nucleotide phosphodiesterase activity" }, { "pred" : "hasExactSynonym", "val" : "negative regulation of cyclic nucleotide phosphodiesterase activity", "xrefs" : [ "GOC:tb" ] }, { "pred" : "hasNarrowSynonym", "val" : "3',5'-cyclic-AMP phosphodiesterase inhibitor" }, { "pred" : "hasNarrowSynonym", "val" : "cAMP phosphodiesterase inhibitor" }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of cyclic nucleotide phosphodiesterase activity" }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of 3',5'-cyclic-AMP phosphodiesterase activity" }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of cAMP phosphodiesterase activity" }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of cGMP phosphodiesterase activity", "xrefs" : [ "GOC:tb" ] }, { "pred" : "hasRelatedSynonym", "val" : "phosphodiesterase inhibitor" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051345", "lbl" : "positive regulation of hydrolase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "hydrolase activator" }, { "pred" : "hasExactSynonym", "val" : "up regulation of hydrolase activity" }, { "pred" : "hasExactSynonym", "val" : "up-regulation of hydrolase activity" }, { "pred" : "hasExactSynonym", "val" : "upregulation of hydrolase activity" }, { "pred" : "hasNarrowSynonym", "val" : "activation of hydrolase activity" }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of hydrolase activity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051346", "lbl" : "negative regulation of hydrolase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "down regulation of hydrolase activity" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of hydrolase activity" }, { "pred" : "hasExactSynonym", "val" : "downregulation of hydrolase activity" }, { "pred" : "hasExactSynonym", "val" : "hydrolase inhibitor" }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of hydrolase activity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051347", "lbl" : "positive regulation of transferase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.", "xrefs" : [ "GOC:ai" ] }, "comments" : [ "This term is useful for grouping, but is too general for manual annotation. Please use a child term instead." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "transferase activator" }, { "pred" : "hasExactSynonym", "val" : "up regulation of transferase activity" }, { "pred" : "hasExactSynonym", "val" : "up-regulation of transferase activity" }, { "pred" : "hasExactSynonym", "val" : "upregulation of transferase activity" }, { "pred" : "hasNarrowSynonym", "val" : "activation of transferase activity" }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of transferase activity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051348", "lbl" : "negative regulation of transferase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.", "xrefs" : [ "GOC:ai" ] }, "comments" : [ "This term is useful for grouping, but is too general for manual annotation. Please use a child term instead." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#gocheck_do_not_manually_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "down regulation of transferase activity" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of transferase activity" }, { "pred" : "hasExactSynonym", "val" : "downregulation of transferase activity" }, { "pred" : "hasExactSynonym", "val" : "transferase inhibitor" }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of transferase activity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051349", "lbl" : "positive regulation of lyase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "lyase activator" }, { "pred" : "hasExactSynonym", "val" : "up regulation of lyase activity" }, { "pred" : "hasExactSynonym", "val" : "up-regulation of lyase activity" }, { "pred" : "hasExactSynonym", "val" : "upregulation of lyase activity" }, { "pred" : "hasNarrowSynonym", "val" : "activation of lyase activity" }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of lyase activity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051350", "lbl" : "negative regulation of lyase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "down regulation of lyase activity" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of lyase activity" }, { "pred" : "hasExactSynonym", "val" : "downregulation of lyase activity" }, { "pred" : "hasExactSynonym", "val" : "lyase inhibitor" }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of lyase activity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051351", "lbl" : "positive regulation of ligase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "ligase activator" }, { "pred" : "hasExactSynonym", "val" : "up regulation of ligase activity" }, { "pred" : "hasExactSynonym", "val" : "up-regulation of ligase activity" }, { "pred" : "hasExactSynonym", "val" : "upregulation of ligase activity" }, { "pred" : "hasNarrowSynonym", "val" : "activation of ligase activity" }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of ligase activity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051352", "lbl" : "negative regulation of ligase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "down regulation of ligase activity" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of ligase activity" }, { "pred" : "hasExactSynonym", "val" : "downregulation of ligase activity" }, { "pred" : "hasExactSynonym", "val" : "ligase inhibitor" }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of ligase activity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051353", "lbl" : "positive regulation of oxidoreductase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "oxidoreductase activator" }, { "pred" : "hasExactSynonym", "val" : "up regulation of oxidoreductase activity" }, { "pred" : "hasExactSynonym", "val" : "up-regulation of oxidoreductase activity" }, { "pred" : "hasExactSynonym", "val" : "upregulation of oxidoreductase activity" }, { "pred" : "hasNarrowSynonym", "val" : "activation of oxidoreductase activity" }, { "pred" : "hasNarrowSynonym", "val" : "ribonucleotide reductase activating enzyme activity" }, { "pred" : "hasNarrowSynonym", "val" : "stimulation of oxidoreductase activity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0009391" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051354", "lbl" : "negative regulation of oxidoreductase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.", "xrefs" : [ "GOC:ai" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "down regulation of oxidoreductase activity" }, { "pred" : "hasExactSynonym", "val" : "down-regulation of oxidoreductase activity" }, { "pred" : "hasExactSynonym", "val" : "downregulation of oxidoreductase activity" }, { "pred" : "hasExactSynonym", "val" : "oxidoreductase inhibitor" }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of oxidoreductase activity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051363", "lbl" : "peptidoglycan-protein cross-linking via L-alanyl-pentaglycyl-murein", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process of linking a protein to peptidoglycan via a carboxy terminal alanine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan.", "xrefs" : [ "PMID:8163519", "PMID:9086265", "RESID:AA0383" ] }, "comments" : [ "Note that this modification may be unique to the species Finegoldia (Peptostreptococcus) magnus." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "RESID:AA0383" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051364", "lbl" : "N-terminal peptidyl-proline N-formylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The formylation of the N-terminal proline of proteins to form the derivative N-formylproline.", "xrefs" : [ "PMID:12051774", "PMID:5464655", "RESID:AA0384" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "RESID:AA0384" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051366", "lbl" : "protein decanoylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The modification of a protein amino acid by formation of an ester or amide with decanoic acid.", 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"peptidyl-threonine octanoylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The octanoylation of peptidyl-threonine to form peptidyl-O3-octanoyl-L-threonine, typical of the protein ghrelin.", "xrefs" : [ "GOC:jsg", "PMID:11546772", "RESID:AA0387" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "RESID:AA0386" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0051369", "lbl" : "peptidyl-threonine decanoylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The decanoylation of peptidyl-threonine to form peptidyl-O3-decanoyl-L-threonine, typical of the protein ghrelin.", "xrefs" : [ "GOC:jsg", "PMID:11546772", "RESID:AA0387" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "RESID:AA0387" } ], "basicPropertyValues" : [ { 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To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "oestrus" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0060210", "lbl" : "metestrus", "type" : "CLASS", "meta" : { "definition" : { "val" : "The estrous cycle phase in which there is subsiding follicular function.", "xrefs" : [ "GOC:dph", "ISBN:0721662544" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0060300", "lbl" : "regulation of cytokine activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0060301", "lbl" : "positive regulation of cytokine activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that increases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0060302", "lbl" : "negative regulation of cytokine activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that decreases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0060314", "lbl" : "regulation of ryanodine-sensitive calcium-release channel activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0060315", "lbl" : "negative regulation of ryanodine-sensitive calcium-release channel activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that decreases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0060316", "lbl" : "positive regulation of ryanodine-sensitive calcium-release channel activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that increases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0060380", "lbl" : "regulation of single-stranded telomeric DNA binding", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of binding to single-stranded telomeric DNA.", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "regulation of telomeric ssDNA binding", "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0060381", "lbl" : "positive regulation of single-stranded telomeric DNA binding", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that increases the frequency, rate or extent of single-stranded telomeric DNA binding.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "positive regulation of telomeric ssDNA binding", "xrefs" : [ "GOC:mah" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0060549", "lbl" : "regulation of fructose 1,6-bisphosphate 1-phosphatase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-04-13T02:07:32Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0060550", "lbl" : "positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-04-13T02:12:33Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0060558", "lbl" : "regulation of calcidiol 1-monooxygenase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-04-13T02:52:18Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0060559", "lbl" : "positive regulation of calcidiol 1-monooxygenase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that increases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-04-13T02:57:28Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0060584", "lbl" : "regulation of prostaglandin-endoperoxide synthase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the rate, frequency or prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "regulation of (PG)H synthase activity", "xrefs" : [ "EC:1.14.99.1" ] }, { "pred" : "hasRelatedSynonym", "val" : "regulation of PG synthetase activity", "xrefs" : [ "EC:1.14.99.1" ] }, { "pred" : "hasRelatedSynonym", "val" : "regulation of fatty acid cyclooxygenase activity", "xrefs" : [ "EC:1.14.99.1" ] }, { "pred" : "hasRelatedSynonym", "val" : "regulation of prostaglandin synthetase activity", "xrefs" : [ "EC:1.14.99.1" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-05-08T02:08:37Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0060585", "lbl" : "positive regulation of prostaglandin-endoperoxide synthase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that increases the rate, frequency or extent of prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasRelatedSynonym", "val" : "positive regulation of (PG)H synthase activity", "xrefs" : [ "EC:1.14.99.1" ] }, { "pred" : "hasRelatedSynonym", "val" : "positive regulation of PG synthetase activity", "xrefs" : [ "EC:1.14.99.1" ] }, { "pred" : "hasRelatedSynonym", "val" : "positive regulation of fatty acid cyclooxygenase activity", "xrefs" : [ "EC:1.14.99.1" ] }, { "pred" : "hasRelatedSynonym", "val" : "positive regulation of prostaglandin synthetase activity", "xrefs" : [ "EC:1.14.99.1" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-05-08T02:12:34Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0060694", "lbl" : "regulation of cholesterol transporter activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the rate, frequency, or extent of cholesterol transporter activity.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-06-08T02:05:27Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0060695", "lbl" : "negative regulation of cholesterol transporter activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that decreases the rate, frequency, or extent of cholesterol transporter activity.", "xrefs" : [ "GOC:BHF", "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-06-08T02:08:34Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0060699", "lbl" : "regulation of endoribonuclease activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-06-08T02:43:10Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0060700", "lbl" : "regulation of ribonuclease activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : 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"http://purl.obolibrary.org/obo/GO_0060702", "lbl" : "negative regulation of endoribonuclease activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that decreases the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-06-08T02:52:27Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0060725", "lbl" : "regulation of coreceptor activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the rate or frequency of coreceptor activity, combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity.", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-06-12T01:20:11Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0061082", "lbl" : "myeloid leukocyte cytokine production", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that contributes to cytokine production by a myeloid cell.", "xrefs" : [ "GOC:dph" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-04-13T11:29:42Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0061097", "lbl" : "regulation of protein tyrosine kinase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity.", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dph" }, { "pred" : 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"basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-08-03T12:00:14Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0090073", "lbl" : "positive regulation of protein homodimerization activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that increases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-09-11T11:15:40Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0090074", "lbl" : "negative regulation of protein homodimerization activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that decreases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2009-09-11T11:15:40Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0090218", "lbl" : "positive regulation of lipid kinase 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"http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-02-05T02:33:33Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0090323", "lbl" : "prostaglandin secretion involved in immune response", "type" : "CLASS", "meta" : { "definition" : { "val" : "The regulated release of a prostaglandin that contributes to the immune response. Prostaglandins are a group of biologically active metabolites which contain a cyclopentane ring.", "xrefs" : [ "GOC:dph", "GOC:tb" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-05-12T10:41:04Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0090360", "lbl" : "platelet-derived growth factor production", "type" : "CLASS", "meta" : { "definition" : { "val" : "The appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.", "xrefs" : [ "GOC:BHF" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2010-07-12T10:32:27Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0090593", "lbl" : "peptidyl-histidine autophosphorylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The phosphorylation by a protein of one or more of its own histidine residues, or a histidine residue on an identical protein.", "xrefs" : [ "PMID:15947782", "PMID:8962061" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { 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"2011-06-23T11:31:10Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0150154" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0097088", "lbl" : "interleukin-17F production", "type" : "CLASS", "meta" : { "definition" : { "val" : "The appearance of interleukin-17F due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.", "xrefs" : [ "GOC:rv", "Wikipedia:Interleukin_17" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "IL-17F production" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "pr" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-06-23T11:32:59Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0097202", "lbl" : "activation of cysteine-type endopeptidase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase.", "xrefs" : [ "GOC:mtg_apoptosis", "PMID:21726810" ] }, "comments" : [ "This term should be used to annotate gene products within the context of cellular processes other than apoptotic cell death (e.g., cell cycle arrest). To annotate gene products involved in activation of cysteine-type endopeptidases where the activation results in apoptotic process, please use the more granular term GO:0006919." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "activation of caspase activity" }, { "pred" : "hasRelatedSynonym", "val" : "activation of metacaspase activity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "pr" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2011-12-19T02:44:04Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0097296", "lbl" : "activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the apoptotic signaling pathway.", "xrefs" : [ "GOC:mtg_apoptosis" ] }, "comments" : [ "Components of the DISC (death-inducing signaling complex) may be annotated to this term. These include ligand-bound receptors such as FAS/CD95 (though care should be taken because FAS can also act as a non-apoptotic signal transducer), and signaling molecules such as FADD (FAS-associated protein with a death domain), cIAPs (cellular inhibitor of apoptosis proteins), c-FLIPs and caspases 8 and 10. Note that GO:0097296 should only be used to annotate gene products directly involved in the initiation or start up of an inactive cysteine-type endopeptidase activity involved in the apoptotic signaling pathway (also known as an initiator caspase). If the evidence provided is not sufficient to account for direct activation of this enzymatic activity, consider using the more generic terms GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway or GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "activation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway" }, { "pred" : "hasNarrowSynonym", "val" : "activation of initiator caspase activity" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "pr" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2012-05-02T03:19:35Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } 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"http://purl.obolibrary.org/obo/GO_0097388", "lbl" : "chemokine (C-C motif) ligand 19 production", "type" : "CLASS", "meta" : { "definition" : { "val" : "The appearance of chemokine (C-C motif) ligand 19 (CCL19) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.", "xrefs" : [ "GOC:rv" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "CCL19 production" }, { "pred" : "hasExactSynonym", "val" : "EBI1 ligand chemokine production" }, { "pred" : "hasExactSynonym", "val" : "ELC production" }, { "pred" : "hasExactSynonym", "val" : "MIP-3-beta production" }, { "pred" : "hasExactSynonym", "val" : "macrophage inflammatory protein-3-beta production" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "pr" }, { "pred" : 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"http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0097390", "lbl" : "chemokine (C-X-C motif) ligand 12 production", "type" : "CLASS", "meta" : { "definition" : { "val" : "The appearance of chemokine (C-X-C motif) ligand 12 (CXCL12) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.", "xrefs" : [ "GOC:rv" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "CXCL12 production" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "pr" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2012-10-23T07:57:28Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0097391", "lbl" : "chemokine (C-X-C motif) ligand 13 production", "type" : "CLASS", "meta" : { "definition" : { "val" : "The appearance of chemokine (C-X-C motif) ligand 13 (CXCL13) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.", "xrefs" : [ "GOC:rv" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "CXCL13 production" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "pr" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2012-10-23T07:58:28Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0097392", "lbl" : "chemokine (C-X-C motif) ligand 16 production", "type" : "CLASS", "meta" : { "definition" : { "val" : "The appearance of chemokine (C-X-C motif) ligand 16 (CXCL16) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.", "xrefs" : [ "GOC:rv" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "CXCL16 production" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "pr" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2012-10-23T07:59:43Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0097722", "lbl" : "sperm motility", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process involved in the controlled movement of a sperm cell.", "xrefs" : [ "GOC:cilia", "GOC:krc" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "sperm movement" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "pr" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2016-09-01T12:00:45Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098628", "lbl" : "peptidyl-N-phospho-arginine dephosphorylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The removal of phosphate residues from peptidyl-N-phospho-arginine to form peptidyl-arginine.", "xrefs" : [ "PMID:23770242" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "dos" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2014-04-17T18:03:31Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098751", "lbl" : "bone cell development", "type" : "CLASS", "meta" : { "definition" : { "val" : "The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.", "xrefs" : [ "GOC:dos" ] }, "comments" : [ "Not to be used for manual annotation. Please choose a more specific cell development term or if not possible, bone or bone tissue development." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098762", "lbl" : "meiotic cell cycle phase", "type" : "CLASS", "meta" : { "definition" : { "val" : "One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.", "xrefs" : [ "GOC:dos" ] }, "comments" : [ "This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098763", "lbl" : "mitotic cell cycle phase", "type" : "CLASS", "meta" : { "definition" : { "val" : "One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.", "xrefs" : [ "GOC:dos" ] }, "comments" : [ "This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098764", "lbl" : "meiosis I cell cycle phase", "type" : "CLASS", "meta" : { "definition" : { "val" : "A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs.", "xrefs" : [ "GOC:dos" ] }, "comments" : [ "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098765", "lbl" : "meiosis II cell cycle phase", "type" : "CLASS", "meta" : { "definition" : { "val" : "A meiotic cell cycle phase that occurs after meiosis I (the first meiotic nuclear division).", "xrefs" : [ "GOC:dos" ] }, "comments" : [ "This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098768", "lbl" : "meiotic prometaphase I", "type" : "CLASS", "meta" : { "definition" : { "val" : "The meiotic cell cycle phase in eukaryotes between meiotic prophase I and meiotic metaphase I. During meiotic prometaphase I, the nuclear envelope breaks down and one kinetochore forms per chromosome. Chromosomes attach to spindle microtubules and begin to move towards the metaphase plate.", "xrefs" : [ "PMID:16012859" ] }, "comments" : [ "This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/24374" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098772", "lbl" : "molecular function regulator activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.", "xrefs" : [ "GOC:dos", "GOC:pt" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_flybase_ribbon", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "molecular function regulator" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/20854" }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/20862" }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/25165" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098822", "lbl" : "peptidyl-cysteine modification to L-cysteine persulfide", "type" : "CLASS", "meta" : { "definition" : { "val" : "The modification of peptidyl-cysteine to form peptidyl-L-cysteine persulfide.", "xrefs" : [ "PMID:11592406" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "RESID:AA0269" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098823", "lbl" : "peptidyl-cysteine modification to S-amindino-L-cysteine", "type" : "CLASS", "meta" : { "definition" : { "val" : "The amidinylation of peptidyl-cysteine to form peptidyl-S-amidino-L-cysteine.", "xrefs" : [ "RESID:AA0335" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "RESID:AA0335" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098824", "lbl" : "peptidyl-cysteine sulfation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The sulfation of peptidyl-cysteine to form S-sulfo-L-cysteine.", "xrefs" : [ "RESID:AA0171" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "RESID:AA0171" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098825", "lbl" : "peptidyl-histidine guanylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The guanylylation of peptidyl-histidine to form (phospho-5'-guanosine)-L-histidine.", "xrefs" : [ "RESID:AA0325" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "xrefs" : [ { "val" : "RESID:AA0325" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0098962", "lbl" : "regulation of postsynaptic neurotransmitter receptor activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity involved in synaptic transmission. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors.", "xrefs" : [ "GOC:dos" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_synapse" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0099522", "lbl" : "cytosolic region", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol.", "xrefs" : [ "GOC:dos" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "region of cytosol" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0099531", "lbl" : "presynaptic process involved in chemical synaptic transmission", "type" : "CLASS", "meta" : { "definition" : { "val" : "The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission.", "xrefs" : [ "GOC:dos" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_synapse" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0099568", "lbl" : "cytoplasmic region", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm.", "xrefs" : [ "GOC:dos" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0099601", "lbl" : "regulation of neurotransmitter receptor activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors.", "xrefs" : [ "GOC:dos" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_synapse" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0099738", "lbl" : "cell cortex region", "type" : "CLASS", "meta" : { "definition" : { "val" : "The complete extent of cell cortex that underlies some some region of the plasma membrane.", "xrefs" : [ "GOC:dos" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "perimembrane region" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0106040", "lbl" : "regulation of GABA-A receptor activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of GABA-A receptor activity.", "xrefs" : [ "PMID:24044036" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "hjd" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2017-07-27T18:47:02Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0106041", "lbl" : "positive regulation of GABA-A receptor activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate or extent of GABA-A receptor activity.", "xrefs" : [ "PMID:24044036" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "hjd" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2017-07-27T18:51:30Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0106042", "lbl" : "negative regulation of GABA-A receptor activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops, prevents or reduces the frequency, rate or extent of GABA-A receptor activity.", "xrefs" : [ "PMID:24044036" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "hjd" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2017-07-27T18:55:03Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0106077", "lbl" : "histone succinylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The modification of a histone by the addition of an succinyl group.", "xrefs" : [ "PMID:29211711" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "hjd" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2017-12-15T18:27:16Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0106225", "lbl" : "peptidyl-lysine 2-hydroxyisobutyrylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The 2-hydroxyisobutyrylation of a lysine residue in a protein.", 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The cargo can be either a RNA or a protein.", "xrefs" : [ "GOC:pg" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "nucleocytoplasmic importin/exportin activity" }, { "pred" : "hasNarrowSynonym", "val" : "miRNA transporter activity" }, { "pred" : "hasNarrowSynonym", "val" : "pre-miRNA transporter activity" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/14336" }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/17399" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "pg" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2017-12-06T13:40:40Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0061717" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasAlternativeId", "val" : "GO:0090631" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0140290", "lbl" : "peptidyl-serine ADP-deribosylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The removal of ADP-ribose from ADP-ribosylserine.", "xrefs" : [ "PMID:28650317", "PMID:29234005" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "pg" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2018-11-22T14:32:30Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0140291", "lbl" : "peptidyl-glutamate ADP-deribosylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The removal of ADP-ribose from ADP-ribosylglutamate.", "xrefs" : [ "PMID:23481255" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "pg" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2018-11-22T14:34:24Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0140438", "lbl" : "protein stearoylation", "type" : "CLASS", "meta" : { "definition" : { "val" : "The covalent attachment of a stearoyl group to an amino acid in a protein.", "xrefs" : [ "PMID:26214738" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/18882" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "pg" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2020-03-11T07:54:48Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0140513", "lbl" : "nuclear protein-containing complex", "type" : "CLASS", "meta" : { "definition" : { "val" : "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus.", "xrefs" : [ "GOC:pg" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "nuclear complex" } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "pg" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2020-09-09T05:12:38Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "cellular_component" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0140657", "lbl" : "ATP-dependent activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient.", "xrefs" : [ "PMID:24878343", "PMID:25750732", "PMID:32933017", "PMID:33818025", "PMID:33873056", "PMID:33988324" ] }, "comments" : [ "Note that this term represents a grouping class that includes all proteins that use ATP hydrolysis to drive a reaction; it is not meant to capture the ATP hydrolysis reaction itself. To annotate ATP hydrolysis, please use 'ATP hydrolysis activity ; GO:0016887'." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate", "http://purl.obolibrary.org/obo/go#goslim_chembl", "http://purl.obolibrary.org/obo/go#goslim_drosophila", "http://purl.obolibrary.org/obo/go#goslim_generic", "http://purl.obolibrary.org/obo/go#goslim_prokaryote", "http://purl.obolibrary.org/obo/go#goslim_yeast" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "ATP hydrolysis-dependent activity" }, { "pred" : "hasExactSynonym", "val" : "ATPase activity" }, { "pred" : "hasExactSynonym", "val" : "ATPase activity, coupled" }, { "pred" : "hasExactSynonym", "val" : "ATPase-dependent activity" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/21612" }, { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/22371" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "pg" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2021-06-15T07:35:06Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0140699", "lbl" : "cyclic GMP-AMP synthase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic GMP-AMP.", "xrefs" : [ "PMID:23258413" ] }, "comments" : [ "Note that this term should not be used for direct annotation. It should be possible to annotate to a more specific child term that descibes the position of the phosphate group on the cGAMP molecule." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "cyclic-GMP-AMP synthase activity" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/21980" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "pg" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2021-08-27T05:05:37Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0140702", "lbl" : "cyclic GMP-AMP binding", "type" : "CLASS", "meta" : { "definition" : { "val" : "Binding to cyclic GMP-AMP (cGAMP) nucleotide.", "xrefs" : [ "PMID:23258412" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/21980" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "pg" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2021-08-27T05:39:31Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "molecular_function" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0140730", "lbl" : "amphiregulin production", "type" : "CLASS", "meta" : { "definition" : { "val" : "The appearance of amphiregulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. 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Instead, select one of the 'regulation' children terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "AREG production" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/21878" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "pg" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2021-11-24T07:09:44Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0140779", "lbl" : "XCL1 production", "type" : "CLASS", "meta" : { "definition" : { "val" : "The appearance of XCL1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.", "xrefs" : [ "PMID:7973732" ] }, "comments" : [ "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "lymphotactin production" } ], "xrefs" : [ { "val" : "Wikipedia:XCL1" } ], "basicPropertyValues" : [ { "pred" : "http://purl.obolibrary.org/obo/IAO_0000233", "val" : "https://github.com/geneontology/go-ontology/issues/23071" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "pg" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2022-03-24T07:11:34Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_0150065", "lbl" : "regulation of deacetylase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of deacetylase activity.", "xrefs" : [ "GOC:aruk", "GOC:bc", 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}, { "pred" : "hasRelatedSynonym", "val" : "up regulation of RNA synthetase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "up regulation of polymerase L", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "up regulation of ribonucleic synthetase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "up-regulation of PB1 proteins", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "up-regulation of PB2 proteins", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "up-regulation of RDRP", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "up-regulation of RNA synthetase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "up-regulation of polymerase L", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "up-regulation of ribonucleic synthetase activity", "xrefs" : [ 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] } }, { "id" : "http://purl.obolibrary.org/obo/GO_1900262", "lbl" : "regulation of DNA-directed DNA polymerase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of DNA-directed DNA polymerase activity.", "xrefs" : [ "GOC:TermGenie" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "regulation of duplicase", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "regulation of DNA duplicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "regulation of DNA nucleotidyltransferase (DNA-directed) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "regulation of DNA replicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "regulation of DNA-dependent DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : 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"regulation of deoxyribonucleic polymerase I", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of epsilon DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of eta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of gamma DNA-directed DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of iota DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of kappa DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of lambda DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of mu DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of nu DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of sigma DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of theta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of zeta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "regulation of sequenase", "xrefs" : [ "GOC:TermGenie" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2012-04-03T11:07:08Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_1900263", "lbl" : "negative regulation of DNA-directed DNA polymerase activity", "type" : "CLASS", "meta" : { "definition" 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duplicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of DNA nucleotidyltransferase (DNA-directed) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of DNA replicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of DNA-dependent DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of DNA-directed DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of deoxyribonucleic acid duplicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of deoxyribonucleic duplicase activity", "xrefs" : [ 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"GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of DNA polymerase I", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of DNA polymerase II", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of DNA polymerase III", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of DNA polymerase V activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of DNA polymerase alpha", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of DNA polymerase beta", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of DNA polymerase gamma", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of Klenow fragment", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of Taq DNA 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] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of gamma DNA-directed DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of iota DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of kappa DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of lambda DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of mu DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of nu DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of sigma DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of theta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of zeta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of DNA polymerase I", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of DNA polymerase II", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of DNA polymerase III", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of DNA polymerase V activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of DNA polymerase alpha", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of DNA polymerase beta", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of DNA polymerase gamma", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of Klenow fragment", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of Taq DNA polymerase", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of Taq Pol I", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of Tca DNA polymerase", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of alpha DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of beta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of delta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of deoxyribonucleic polymerase I", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of epsilon DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of eta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of gamma DNA-directed DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of iota DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of kappa DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of lambda DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of mu DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of nu DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of sigma DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of theta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of zeta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of DNA polymerase I", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of DNA polymerase II", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of DNA polymerase III", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of DNA polymerase V activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of DNA polymerase alpha", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of DNA polymerase beta", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of DNA polymerase gamma", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of DNA-directed DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of Klenow fragment", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of Taq DNA polymerase", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of Taq Pol I", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of Tca DNA polymerase", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of alpha DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of beta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of delta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of deoxyribonucleic polymerase I", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of epsilon DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of eta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of gamma DNA-directed DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of iota DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of kappa DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of lambda DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of mu DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of nu DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of sigma DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of theta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of zeta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of DNA polymerase I", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of DNA polymerase II", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of DNA polymerase III", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of DNA polymerase V activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of DNA polymerase alpha", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of DNA polymerase beta", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of DNA polymerase gamma", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of Klenow fragment", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of Taq DNA polymerase", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of Taq Pol I", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of Tca DNA polymerase", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of alpha DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of beta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of delta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of deoxyribonucleic polymerase I", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of epsilon DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of eta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of gamma DNA-directed DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of iota DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of kappa DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of lambda DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of mu DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of nu DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of sigma DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of theta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of zeta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "down regulation of sequenase", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "down-regulation of sequenase", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "downregulation of sequenase", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "inhibition of sequenase", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "negative regulation of sequenase", "xrefs" : [ "GOC:TermGenie" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "tb" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2012-04-03T11:07:18Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_1900264", "lbl" : "positive regulation of DNA-directed DNA polymerase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate or extent of DNA-directed DNA polymerase activity.", "xrefs" : [ "GOC:TermGenie" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasBroadSynonym", "val" : "activation of duplicase", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasBroadSynonym", "val" : "positive regulation of duplicase", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasBroadSynonym", "val" : "up regulation of duplicase", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasBroadSynonym", "val" : "up-regulation of duplicase", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasBroadSynonym", "val" : "upregulation of duplicase", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "activation of DNA duplicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "activation of DNA nucleotidyltransferase (DNA-directed) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "activation of DNA replicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "activation of DNA-dependent DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "activation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "activation of deoxyribonucleic acid duplicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "activation of deoxyribonucleic duplicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of DNA duplicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of DNA nucleotidyltransferase (DNA-directed) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of DNA replicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of DNA-dependent DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of deoxyribonucleic acid duplicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of deoxyribonucleic duplicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of DNA duplicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of DNA nucleotidyltransferase (DNA-directed) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of DNA replicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of DNA-dependent DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of DNA-directed DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of deoxyribonucleic acid duplicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of deoxyribonucleic duplicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of DNA duplicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of DNA nucleotidyltransferase (DNA-directed) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of DNA replicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of DNA-dependent DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of DNA-directed DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of deoxyribonucleic acid duplicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of deoxyribonucleic duplicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of DNA duplicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of DNA nucleotidyltransferase (DNA-directed) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of DNA replicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of DNA-dependent DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of DNA-directed DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of deoxyribonucleic acid duplicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of deoxyribonucleic duplicase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of DNA polymerase I", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of DNA polymerase II", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of DNA polymerase III", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of DNA polymerase V activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of DNA polymerase alpha", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of DNA polymerase beta", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of DNA polymerase gamma", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of DNA-directed DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of Klenow fragment", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of Taq DNA polymerase", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of Taq Pol I", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of Tca DNA polymerase", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of alpha DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of beta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of delta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of deoxyribonucleic polymerase I", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of epsilon DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of eta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of gamma DNA-directed DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of iota DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of kappa DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of lambda DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of mu DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of nu DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of sigma DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of theta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of zeta DNA polymerase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of DNA polymerase I", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of DNA polymerase II", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of DNA polymerase III", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of DNA polymerase V activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of DNA polymerase alpha", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of DNA polymerase beta", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of DNA polymerase gamma", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of Klenow fragment", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of Taq DNA polymerase", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of Taq Pol I", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of Tca DNA polymerase", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of alpha DNA polymerase activity", "xrefs" 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"GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of N5,10-methylenetetrahydrofolate reductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of N5,N10-methylenetetrahydrofolate 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"hasNarrowSynonym", "val" : "inhibition of 5,10-methylenetetrahydrofolate reductase (NADPH) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of 5,10-methylenetetrahydropteroylglutamate reductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of 5-methyltetrahydrofolate:NAD oxidoreductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity", "xrefs" : [ 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"val" : "negative regulation of methylenetetrahydrofolate reductase [NAD(P)H]", "xrefs" : [ "GOC:TermGenie" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "rph" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2015-02-05T13:26:25Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_1903870", "lbl" : "positive regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity.", "xrefs" : [ "GOC:BHF", "GOC:TermGenie", "GOC:rph", "GO_REF:0000059", "PMID:24769206" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "positive regulation of 5,10-CH(2)-H(4)folate reductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of 5,10-CH2-H4folate reductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity", "xrefs" : [ 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"hasExactSynonym", "val" : "up-regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of N5,10-methylenetetrahydrofolate reductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of N5,N10-methylenetetrahydrofolate reductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of methylenetetrahydrofolate reductase (NADPH2)", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of 5,10-CH(2)-H(4)folate reductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of 5,10-CH2-H4folate reductase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of 5,10-methylenetetrahydrofolate reductase (NADPH) 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acyltransferase decarboxylating", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "upregulation of SPT", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "upregulation of acyl-CoA:serine C-2 acyltransferase decarboxylating", "xrefs" : [ "GOC:TermGenie" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "rl" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2015-05-15T08:27:45Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_1904223", "lbl" : "regulation of glucuronosyltransferase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that modulates the frequency, rate or extent of glucuronosyltransferase activity.", "xrefs" : [ "GOC:BHF", "GOC:TermGenie", "GOC:rl", "GO_REF:0000059", "PMID:20610558" ] }, 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"pred" : "hasExactSynonym", "val" : "regulation of UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "regulation of UDPGA transferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "regulation of UDPGA-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "regulation of UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "regulation of uridine 5'-diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "regulation of uridine diphosphate glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "regulation of uridine diphosphoglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "regulation of uridine diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of 1-naphthol glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of 1-naphthol-UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of 17-OH steroid UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of 3-OH androgenic UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of 4-nitrophenol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of 4-nitrophenol UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of UDP glucuronate-estriol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of bilirubin UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of bilirubin UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of bilirubin glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of bilirubin monoglucuronide glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of bilirubin uridine diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of ciramadol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of estriol UDPglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of estrone UDPglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of morphine glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of p-nitrophenol UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of p-nitrophenol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of p-nitrophenylglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of p-phenylphenol glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of phenyl-UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of pnp-UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "regulation of PNP-UDPGT", "xrefs" : [ "GOC:TermGenie" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "rl" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2015-05-15T08:44:20Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_1904224", "lbl" : "negative regulation of glucuronosyltransferase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that stops, prevents or reduces the frequency, rate or extent of glucuronosyltransferase activity.", "xrefs" : [ "GOC:BHF", "GOC:TermGenie", "GOC:rl", "GO_REF:0000059", "PMID:20610558" ] }, "comments" : [ "i2 UDP-glucuronosyltransferase splice species alter glucuronidation activity of i1 UDP-glucuronosyltransferase splice species" ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "down regulation of GT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down regulation of UDP glucuronic acid transferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down regulation of UDP glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down regulation of UDP glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down regulation of UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down regulation of UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down regulation of UDPGA transferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down regulation of UDPGA-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down regulation of UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down regulation of glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down regulation of uridine 5'-diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down regulation of uridine diphosphate glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down regulation of uridine diphosphoglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down regulation of uridine diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down-regulation of GT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down-regulation of UDP glucuronic acid transferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down-regulation of UDP glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down-regulation of UDP glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down-regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down-regulation of UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down-regulation of UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down-regulation of UDPGA transferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down-regulation of UDPGA-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down-regulation of UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down-regulation of glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down-regulation of uridine 5'-diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down-regulation of uridine diphosphate glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down-regulation of uridine diphosphoglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "down-regulation of uridine diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of GT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of UDP glucuronic acid transferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of UDP glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of UDP glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of UDPGA transferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of UDPGA-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of uridine 5'-diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of uridine diphosphate glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of uridine diphosphoglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "downregulation of uridine diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "negative regulation of GT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "negative regulation of UDP glucuronic acid transferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "negative regulation of UDP glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "negative regulation of UDP glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "negative regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "negative regulation of UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "negative regulation of UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "negative regulation of UDPGA transferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "negative regulation of UDPGA-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "negative regulation of UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "negative regulation of uridine 5'-diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "negative regulation of uridine diphosphate glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "negative regulation of uridine diphosphoglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "negative regulation of uridine diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of 1-naphthol glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of 1-naphthol-UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of 17-OH steroid UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of 3-OH androgenic UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of 4-nitrophenol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of 4-nitrophenol UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of UDP glucuronate-estriol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of bilirubin UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of bilirubin UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of bilirubin glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of bilirubin monoglucuronide glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of bilirubin uridine diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of ciramadol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of estriol UDPglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of estrone UDPglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of morphine glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of p-nitrophenol UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of p-nitrophenol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of p-nitrophenylglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of p-phenylphenol glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of phenyl-UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of pnp-UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of 1-naphthol glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of 1-naphthol-UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of 17-OH steroid UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of 3-OH androgenic UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of 4-nitrophenol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of 4-nitrophenol UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of UDP glucuronate-estriol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of bilirubin UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of bilirubin UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of bilirubin glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of bilirubin monoglucuronide glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of bilirubin uridine diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of ciramadol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of estriol UDPglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of estrone UDPglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of morphine glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of p-nitrophenol UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of p-nitrophenol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of p-nitrophenylglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of p-phenylphenol glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of phenyl-UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of pnp-UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of 1-naphthol glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of 1-naphthol-UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of 17-OH steroid UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of 3-OH androgenic UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of 4-nitrophenol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of 4-nitrophenol UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of UDP glucuronate-estradiol-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of UDP glucuronate-estriol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of UDP-glucuronate-bilirubin glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of bilirubin UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of bilirubin UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of bilirubin glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of bilirubin monoglucuronide glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of bilirubin uridine diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of ciramadol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of estriol UDPglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of estrone UDPglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of morphine glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of p-hydroxybiphenyl UDP glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of p-nitrophenol UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of p-nitrophenol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of p-nitrophenylglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of p-phenylphenol glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of phenyl-UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of pnp-UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "downregulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of 1-naphthol glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of 1-naphthol-UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of 17-OH steroid UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of 3-OH androgenic UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of 4-methylumbelliferone UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of 4-nitrophenol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of 4-nitrophenol UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of GT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of UDP glucuronate-estradiol-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of UDP glucuronate-estriol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of UDP glucuronic acid transferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of UDP glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of UDP glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of UDP-glucuronate-bilirubin glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of UDPGA transferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of UDPGA-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of bilirubin UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of bilirubin UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of bilirubin glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of bilirubin monoglucuronide glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of bilirubin uridine diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of ciramadol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of estriol UDPglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of estrone UDPglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of morphine glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of p-hydroxybiphenyl UDP glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of p-nitrophenol UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of p-nitrophenol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of p-nitrophenylglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of p-phenylphenol glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of phenyl-UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of pnp-UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of uridine 5'-diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of uridine diphosphate glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of uridine diphosphoglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "inhibition of uridine diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of 1-naphthol glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of 1-naphthol-UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of 17-OH steroid UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of 3-OH androgenic UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of 4-nitrophenol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of 4-nitrophenol UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of UDP glucuronate-estriol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of bilirubin UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of bilirubin UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of bilirubin glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of bilirubin monoglucuronide glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of bilirubin uridine diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of ciramadol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of estriol UDPglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of estrone UDPglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of morphine glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of p-nitrophenol UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of p-nitrophenol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of p-nitrophenylglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of p-phenylphenol glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of phenyl-UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of pnp-UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "negative regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "down regulation of PNP-UDPGT", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "down-regulation of PNP-UDPGT", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "downregulation of PNP-UDPGT", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "inhibition of PNP-UDPGT", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasRelatedSynonym", "val" : "negative regulation of PNP-UDPGT", "xrefs" : [ "GOC:TermGenie" ] } ], "basicPropertyValues" : [ { "pred" : "http://www.geneontology.org/formats/oboInOwl#created_by", "val" : "rl" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#creation_date", "val" : "2015-05-15T08:44:26Z" }, { "pred" : "http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_1904225", "lbl" : "positive regulation of glucuronosyltransferase activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate or extent of glucuronosyltransferase activity.", "xrefs" : [ "GOC:BHF", "GOC:TermGenie", "GOC:rl", "GO_REF:0000059", "PMID:20610558" ] }, "comments" : [ "i2 UDP-glucuronosyltransferase splice species alter glucuronidation activity of i1 UDP-glucuronosyltransferase splice species" ], "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasExactSynonym", "val" : "positive regulation of GT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of UDP glucuronic acid transferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of UDP glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of UDP glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of UDPGA transferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of UDPGA-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of uridine 5'-diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of uridine diphosphate glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of uridine diphosphoglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "positive regulation of uridine diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of GT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of UDP glucuronic acid transferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of UDP glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of UDP glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of UDPGA transferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of UDPGA-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of uridine 5'-diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of uridine diphosphate glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of uridine diphosphoglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up regulation of uridine diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of GT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of UDP glucuronic acid transferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of UDP glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of UDP glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of UDPGA transferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of UDPGA-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of uridine 5'-diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of uridine diphosphate glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of uridine diphosphoglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "up-regulation of uridine diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of GT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of UDP glucuronic acid transferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of UDP glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of UDP glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of UDPGA transferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of UDPGA-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of uridine 5'-diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of uridine diphosphate glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of uridine diphosphoglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasExactSynonym", "val" : "upregulation of uridine diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of 1-naphthol glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of 1-naphthol-UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of 17-OH steroid UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of 3-OH androgenic UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of 4-methylumbelliferone UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of 4-nitrophenol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of 4-nitrophenol UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of GT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of UDP glucuronate-estradiol-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of UDP glucuronate-estriol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of UDP glucuronic acid transferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of UDP glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of UDP glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of UDP-glucuronate-bilirubin glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of UDPGA transferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of UDPGA-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of bilirubin UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of bilirubin UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of bilirubin glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of bilirubin monoglucuronide glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of bilirubin uridine diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of ciramadol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of estriol UDPglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of estrone UDPglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of morphine glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of p-hydroxybiphenyl UDP glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of p-nitrophenol UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of p-nitrophenol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of p-nitrophenylglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of p-phenylphenol glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of phenyl-UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of pnp-UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of uridine 5'-diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of uridine diphosphate glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of uridine diphosphoglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of uridine diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of 1-naphthol glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of 1-naphthol-UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of 17-OH steroid UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of 3-OH androgenic UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of 4-nitrophenol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of 4-nitrophenol UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of UDP glucuronate-estriol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of bilirubin UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of bilirubin UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of bilirubin glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of bilirubin monoglucuronide glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of bilirubin uridine diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of ciramadol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of estriol UDPglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of estrone UDPglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of morphine glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of p-nitrophenol UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of p-nitrophenol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of p-nitrophenylglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of p-phenylphenol glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of phenyl-UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of pnp-UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "positive regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of 1-naphthol glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of 1-naphthol-UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of 17-OH steroid UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of 3-OH androgenic UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of 4-nitrophenol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of 4-nitrophenol UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of UDP glucuronate-estriol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of bilirubin UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of bilirubin UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of bilirubin glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of bilirubin monoglucuronide glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of bilirubin uridine diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of ciramadol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of estriol UDPglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of estrone UDPglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of morphine glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of p-nitrophenol UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of p-nitrophenol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of p-nitrophenylglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of p-phenylphenol glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of phenyl-UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of pnp-UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of 1-naphthol glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of 1-naphthol-UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of 17-OH steroid UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of 3-OH androgenic UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of 4-nitrophenol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of 4-nitrophenol UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of UDP glucuronate-estriol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of bilirubin UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of bilirubin UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of bilirubin glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of bilirubin monoglucuronide glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of bilirubin uridine diphosphoglucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of ciramadol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of estriol UDPglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of estrone UDPglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of morphine glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of p-nitrophenol UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of p-nitrophenol UDP-glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of p-nitrophenylglucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of p-phenylphenol glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of phenyl-UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of pnp-UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "up-regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "upregulation of 1-naphthol glucuronyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "upregulation of 1-naphthol-UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "upregulation of 17-OH steroid UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "upregulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "upregulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "upregulation of 3-OH androgenic UDPGT activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "upregulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "upregulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "upregulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "upregulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity", "xrefs" : 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"pred" : "hasNarrowSynonym", "val" : "down regulation of azurin", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of bacterial-type ferredoxin", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of chloroplast-type ferredoxin", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of copper electron carrier", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of dicluster bacterial-type ferredoxin", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of electron acceptor activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of electron donor activity", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down regulation of electron transfer flavoprotein", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down 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"down-regulation of electron transfer flavoprotein, group II", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of high-potential iron-sulfur carrier", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of iron-sulfur electron transfer carrier", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of monocluster bacterial-type ferredoxin", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of mononuclear iron electron carrier", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of polyferredoxin", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of redox-active disulfide bond electron carrier", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "down-regulation of rubredoxin", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", 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"http://www.geneontology.org/formats/oboInOwl#hasOBONamespace", "val" : "biological_process" } ] } }, { "id" : "http://purl.obolibrary.org/obo/GO_1904734", "lbl" : "positive regulation of electron transfer activity", "type" : "CLASS", "meta" : { "definition" : { "val" : "Any process that activates or increases the frequency, rate or extent of electron transfer activity.", "xrefs" : [ "GOC:TermGenie", "GO_REF:0000059", "PMID:25416781" ] }, "subsets" : [ "http://purl.obolibrary.org/obo/go#gocheck_do_not_annotate" ], "synonyms" : [ { "pred" : "hasNarrowSynonym", "val" : "activation of 2Fe-2S electron transfer carrier", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of 3Fe-4S/4Fe-4S electron transfer carrier", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of adrenodoxin-type ferredoxin", "xrefs" : [ "GOC:TermGenie" ] }, { "pred" : "hasNarrowSynonym", "val" : "activation of amicyanin", "xrefs" : [ "GOC:TermGenie" ] 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