# GORULE violations assigned by AgBase

## SUMMARY

This report generated on 2026-05-21

## Contents

[gorule-0000002](#gorule-0000002)[No 'NOT' annotations to binding ; GO:0005488 or 'protein binding ; GO:0005515']{}

[gorule-0000005](#gorule-0000005)[IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations are not allowed for direct annotations to 'protein binding ; GO:0005515 or GO:0005488 binding'']{}

[gorule-0000008](#gorule-0000008)[No annotations should be made to uninformative high level terms]{}

[gorule-0000013](#gorule-0000013)[Taxon-appropriate annotation check]{}

[gorule-0000020](#gorule-0000020)[Automatic repair of annotations to merged or obsoleted terms]{}

[gorule-0000046](#gorule-0000046)[The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.]{}

[gorule-0000061](#gorule-0000061)[Allowed gene product to term relations (gp2term)]{}

[gorule-0000063](#gorule-0000063)[Annotations using ISS/ISA/ISO evidence should refer to a gene product (in the 'with' column)]{}

[gorule-0000065](#gorule-0000065)[Annotations to term that are candidates for obsoletion should be produce a warning]{}

## MESSAGES

###gorule-0000002

No 'NOT' annotations to binding ; GO:0005488 or 'protein binding ; GO:0005515'

* total: 2
#### Messages
* ERROR - Violates GO Rule:GORULE:0000002: No 'NOT' annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB	P63026	VAMP2	NOT|enables	GO:0005515	PMID:20702699	IPI	UniProtKB:F1N348	F	Vesicle-associated membrane protein 2	VAMP2|SYB2	protein	taxon:9913	20141106	AgBase		UniProtKB:P63026
`
* ERROR - Violates GO Rule:GORULE:0000002: No 'NOT' annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB	P63026	VAMP2	NOT|enables	GO:0005515	PMID:20702699	IPI	UniProtKB:P20488	F	Vesicle-associated membrane protein 2	VAMP2|SYB2	protein	taxon:9913	20141106	AgBase		UniProtKB:P63026
`

###gorule-0000005

IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations are not allowed for direct annotations to 'protein binding ; GO:0005515 or GO:0005488 binding''

* total: 6
#### Messages
* WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`MGI	MGI:98725	Tgfb1	enables	GO:0005515	GO_REF:0000024	ISS	UniProtKB:P01137	F	transforming growth factor, beta 1	TGF-beta 1|TGF-beta1|TGFbeta1|Tgfb|Tgfb-1	protein	NCBITaxon:10090	20141202	AgBase		MGI:MGI:98725
`
* WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`RGD	69051	Tgfb1	enables	GO:0005515	GO_REF:0000024	ISS	UniProtKB:P01137	F	transforming growth factor, beta 1		protein	NCBITaxon:10116	20141202	AgBase		RGD:69051
`
* WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB	P18341	TGFB1	enables	GO:0005515	GO_REF:0000024	ISS	UniProtKB:P01137	F	Transforming growth factor beta-1 proprotein	TGFB1	protein	taxon:9913	20141202	AgBase		UniProtKB:P18341
`
* WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB	P68399	CSNK2A1	enables	GO:0005515	GO_REF:0000024	ISS	UniProtKB:P68400	F	Casein kinase II subunit alpha	CSNK2A1|CK2A1	protein	taxon:9913	20070615	AgBase		UniProtKB:P68399
`
* WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB	Q5EA77	SNX17	enables	GO:0005515	GO_REF:0000024	ISS	UniProtKB:Q15036	F	Sorting nexin-17	SNX17	protein	taxon:9913	20070412	AgBase		UniProtKB:Q5EA77
`
* WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB	P54831	TGFB1	enables	GO:0005515	GO_REF:0000024	ISS	UniProtKB:P01137	F	Transforming growth factor beta-1 proprotein	TGFB1	protein	taxon:9615	20141202	AgBase		UniProtKB:P54831
`

###gorule-0000008

No annotations should be made to uninformative high level terms

* total: 48
#### Messages
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	I3L8Q3	CSF2	involved_in	GO:0072651	PMID:16792532	IMP		P	Granulocyte-macrophage colony-stimulating factor	CSF2	protein	taxon:9823	20150530	AgBase	occurs_in(CL:1000274)	UniProtKB:I3L8Q3
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P17741	HMGB2	involved_in	GO:0043388	GO_REF:0000024	ISS	UniProtKB:P30681	P	High mobility group protein B2	HMGB2|HMG2	protein	taxon:9823	20150508	AgBase		UniProtKB:P17741
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q29118	CSF2	involved_in	GO:0072651	PMID:16792532	IMP		P	Granulocyte-macrophage colony-stimulating factor	CSF2	protein	taxon:9823	20150530	AgBase	occurs_in(CL:1000274)	UniProtKB:Q29118
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q4PLW0	PLIN2	located_in	GO:0005622	PMID:21420243	IDA		C	Perilipin-2	PLIN2|ADFP|ADRP	protein	taxon:9823	20150513	AgBase	part_of(CL:0000187),part_of(UBERON:0001381)	UniProtKB:Q4PLW0
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P05019	IGF1	involved_in	GO:2000679	PMID:15059951	IDA		P	Insulin-like growth factor 1	IGF1|IBP1|IGF-1	protein	taxon:9606	20150710	AgBase	has_input(UniProtKB:O97894)|has_input(UniProtKB:I3LUZ9)	UniProtKB:P05019
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	F1MHQ4	FABP4	involved_in	GO:0001816	GO_REF:0000024	ISS	UniProtKB:P04117	P	Cytosolic fatty-acid binding proteins domain-containing protein	FABP4	protein	taxon:9913	20160205	AgBase		UniProtKB:F1MHQ4
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P01239	PRL	involved_in	GO:0009058	PMID:6754783	IDA		P	Prolactin	PRL	protein	taxon:9913	20150522	AgBase	occurs_in(UBERON:0001911),happens_during(GO:0007595)	UniProtKB:P01239
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P04272	ANXA2	located_in	GO:0043231	PMID:18597635	IDA		C	Annexin A2	ANXA2|ANX2	protein	taxon:9913	20140514	AgBase		UniProtKB:P04272
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P11052	CSF2	involved_in	GO:0072651	GO_REF:0000024	ISS	UniProtKB:Q29118	P	Granulocyte-macrophage colony-stimulating factor	CSF2	protein	taxon:9913	20150530	AgBase		UniProtKB:P11052
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P18203	FKBP1A	involved_in	GO:0032092	PMID:11341768	ISA	UniProtKB:P62942	P	Peptidyl-prolyl cis-trans isomerase FKBP1A	FKBP1A|FKBP1	protein	taxon:9913	20090205	AgBase		UniProtKB:P18203
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P46282	IL12B	involved_in	GO:0032609	PMID:12133628	IDA		P	Interleukin-12 subunit beta	IL12B	protein	taxon:9913	20150131	AgBase		UniProtKB:P46282
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P48035	FABP4	involved_in	GO:0001816	GO_REF:0000024	ISS	UniProtKB:P04117	P	Fatty acid-binding protein, adipocyte	FABP4	protein	taxon:9913	20160205	AgBase		UniProtKB:P48035
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P54349	IL12A	involved_in	GO:0032609	PMID:12133628	IDA		P	Interleukin-12 subunit alpha	IL12A	protein	taxon:9913	20150131	AgBase		UniProtKB:P54349
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P68107	FKBP1B	located_in	GO:0043231	PMID:12508222	ISA	UniProtKB:P97534	C	Peptidyl-prolyl cis-trans isomerase FKBP1B	FKBP1B|FKBP12.6	protein	taxon:9913	20130311	AgBase		UniProtKB:P68107
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P81287	ANXA5	located_in	GO:0005622	GO_REF:0000024	ISS	UniProtKB:P08758	C	Annexin A5	ANXA5|ANX5	protein	taxon:9913	20061003	AgBase		UniProtKB:P81287
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q2HJ92	PRKRA	located_in	GO:0005622	GO_REF:0000024	ISS	UniProtKB:Q9WTX2	C	Interferon-inducible double-stranded RNA-dependent protein kinase activator A	PRKRA	protein	taxon:9913	20070616	AgBase		UniProtKB:Q2HJ92
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`Xenbase	XB-GENE-5836974	fkbp1a.L	acts_upstream_of_or_within	GO:0032092	PMID:11341768	ISA	UniProtKB:P62942	P	FKBP prolyl isomerase 1A L homeolog	fkbp1|fkbp 12|fkbp-12|pkc12|pkci2|ppiase|xfkbp1a	protein	taxon:8355	20090205	AgBase		
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	F1NBL0	MUC6	located_in	GO:0043231	PMID:6749856	IDA		C	Mucin-6	MUC6	protein	taxon:9031	20170210	AgBase		UniProtKB:F1NBL0
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	F1P4G3	HIPK2	involved_in	GO:0043388	GO_REF:0000024	ISS	UniProtKB:Q9QZR5	P	non-specific serine/threonine protein kinase	HIPK2	protein	taxon:9031	20061117	AgBase		UniProtKB:F1P4G3
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	O42391	O42391	involved_in	GO:0030031	PMID:16912080	IMP		P	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform		protein	taxon:9031	20160121	AgBase	occurs_in(UBERON:0006215)	UniProtKB:O42391
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	O42410	IKZF1	involved_in	GO:0002377	PMID:20602434	TAS		P	DNA-binding protein Ikaros	IKZF1|IK|IKAROS|ZNFN1A1	protein	taxon:9031	20120130	AgBase		UniProtKB:O42410
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	O42410	IKZF1	involved_in	GO:0016049	PMID:20602434	TAS		P	DNA-binding protein Ikaros	IKZF1|IK|IKAROS|ZNFN1A1	protein	taxon:9031	20120130	AgBase		UniProtKB:O42410
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	O73933	O73933	involved_in	GO:0043392	PMID:19247943	NAS		P	BHLH domain-containing protein		protein	taxon:9031	20130308	AgBase		UniProtKB:O73933
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P01012	SERPINB14	located_in	GO:0043231	PMID:6749856	IDA		C	Ovalbumin	SERPINB14	protein	taxon:9031	20170210	AgBase		UniProtKB:P01012
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P05153	PCK1	involved_in	GO:0019953	PMID:14653465	IMP		P	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	PCK1	protein	taxon:9031	20110602	AgBase		UniProtKB:P05153
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P09654	VIM	located_in	GO:0042995	PMID:25262821	IDA		C	Vimentin	VIM	protein	taxon:9031	20150721	AgBase		UniProtKB:P09654
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P30371	TGFB2	involved_in	GO:0008219	PMID:10401723	ISA	UniProtKB:P61812	P	Transforming growth factor beta-2 proprotein	TGFB2	protein	taxon:9031	20091203	AgBase		UniProtKB:P30371
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P63283	UBE2I	enables	GO:0008134	PMID:23382206	IPI	UniProtKB:P48434	F	SUMO-conjugating enzyme UBC9	UBE2I|UBC9|UBCE9	protein	taxon:9031	20140514	AgBase		UniProtKB:P63283
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P79760	CYP1A4	located_in	GO:0043231	PMID:20580800	IDA		C	Cytochrome P450 1A4	CYP1A4	protein	taxon:9031	20201224	AgBase	part_of(UBERON:0002107)	UniProtKB:P79760
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P79761	CYP1A5	located_in	GO:0043231	PMID:23474502	IDA		C	Cytochrome P450 1A5	CYP1A5	protein	taxon:9031	20201224	AgBase		UniProtKB:P79761
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q00649	HSPB1	located_in	GO:0005622	PMID:15135047	ISS	UniProtKB:P14602	C	Heat shock protein beta-1	HSPB1	protein	taxon:9031	20140201	AgBase		UniProtKB:Q00649
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q00944	PTK2	involved_in	GO:0032092	PMID:15340073	IMP		P	Focal adhesion kinase 1	PTK2|FAK|FAK1	protein	taxon:9031	20160113	AgBase		UniProtKB:Q00944
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q05423	FABP7	enables	GO:0008134	PMID:10090146	TAS		F	Fatty acid-binding protein, brain	FABP7	protein	taxon:9031	20100429	AgBase		UniProtKB:Q05423
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q06900	ChALK5	involved_in	GO:0043393	PMID:10885742	ISA	UniProtKB:Q64729	P	TGF-beta receptor type-1	ChALK5	protein	taxon:9031	20130311	AgBase		UniProtKB:Q06900
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q679P3	PDLIM7	enables	GO:0008134	PMID:15302601	IPI	UniProtKB:O93288	F	PDZ and LIM domain protein 7	PDLIM7|LMP|RCJMB04_14g20	protein	taxon:9031	20150408	AgBase		UniProtKB:Q679P3
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q679P3	PDLIM7	enables	GO:0008134	PMID:15302601	IPI	UniProtKB:Q9PWE8	F	PDZ and LIM domain protein 7	PDLIM7|LMP|RCJMB04_14g20	protein	taxon:9031	20150408	AgBase		UniProtKB:Q679P3
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q8QGW7	LITAF	involved_in	GO:0001816	PMID:18539728	TAS		P	Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog	LITAF|SIMPLE	protein	taxon:9031	20090716	AgBase		UniProtKB:Q8QGW7
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q8QGW7	LITAF	involved_in	GO:0019953	PMID:18539728	TAS		P	Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog	LITAF|SIMPLE	protein	taxon:9031	20090716	AgBase		UniProtKB:Q8QGW7
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q90694	CDC42	located_in	GO:0042995	GO_REF:0000024	ISS	UniProtKB:P60766	C	Cell division control protein 42 homolog	CDC42	protein	taxon:9031	20060411	AgBase		UniProtKB:Q90694
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q90998	Q90998	involved_in	GO:0016049	PMID:8167376	ISA	UniProtKB:P26342	P	ZP domain-containing protein		protein	taxon:9031	20091203	AgBase		UniProtKB:Q90998
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q90998	Q90998	involved_in	GO:0043393	PMID:8167376	ISA	UniProtKB:P26342	P	ZP domain-containing protein		protein	taxon:9031	20091203	AgBase		UniProtKB:Q90998
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q91035	SHH	involved_in	GO:0090269	PMID:10524628	IMP		P	Sonic hedgehog protein	SHH	protein	taxon:9031	20141202	AgBase		UniProtKB:Q91035
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q91035	SHH	involved_in	GO:0090269	PMID:9187149	IDA		P	Sonic hedgehog protein	SHH	protein	taxon:9031	20150522	AgBase		UniProtKB:Q91035
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q98UI9	MUC5B	located_in	GO:0043231	PMID:6749856	IDA		C	Mucin-5B	MUC5B	protein	taxon:9031	20170210	AgBase		UniProtKB:Q98UI9
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q9PRS8	Q9PRS8	enables	GO:0043167	PMID:15263013	TAS		F	Ovocleidin-17		protein	taxon:9031	20080730	AgBase		UniProtKB:Q9PRS8
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q9YGL6	PALM	located_in	GO:0005622	PMID:9813098	IDA		C	Paralemmin-1	PALM	protein	taxon:9031	20170202	AgBase	part_of(UBERON:0000955)	UniProtKB:Q9YGL6
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q9YGL6	PALM	located_in	GO:0005622	PMID:9813098	IDA		C	Paralemmin-1	PALM	protein	taxon:9031	20170202	AgBase	part_of(UBERON:0000955)	UniProtKB:Q9YGL6-2
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	Q9YGL6	PALM	located_in	GO:0005622	PMID:9813098	IDA		C	Paralemmin-1	PALM	protein	taxon:9031	20170202	AgBase	part_of(UBERON:0000955)	UniProtKB:Q9YGL6-3
`

###gorule-0000013

Taxon-appropriate annotation check

* total: 3
#### Messages
* ERROR - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	F1NNP2	TGFB2	involved_in	GO:0051795	GO_REF:0000024	ISS	UniProtKB:P61812	P	Transforming growth factor beta	TGFB2	protein	taxon:9031	20141202	AgBase		UniProtKB:F1NNP2
`
* WARNING - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	P63026	VAMP2	enables	GO:0019905	PMID:21926345	IPI	UniProtKB:Q3SWZ3	F	Vesicle-associated membrane protein 2	VAMP2|SYB2	protein	taxon:9913	20140516	AgBase		UniProtKB:P63026
`
* WARNING - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	P08998	GH	involved_in	GO:0035846	PMID:24744268	IDA		P	Somatotropin	GH	protein	taxon:9031	20150219	AgBase		UniProtKB:P08998
`

###gorule-0000020

Automatic repair of annotations to merged or obsoleted terms

* total: 2
#### Messages
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	P38529	HSF1	involved_in	GO:0010628	PMID:11387221	IMP		P	Heat shock factor protein 1	HSF1	protein	taxon:9031	20151218	AgBase	part_of(GO:0034605)|part_of(GO:1903936)|part_of(GO:0071417)|has_input(UniProtKB:P11501)	UniProtKB:P38529
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	P38531	HSF3	involved_in	GO:0010628	PMID:11387221	IMP		P	Heat shock factor protein 3	HSF3	protein	taxon:9031	20151218	AgBase	part_of(GO:0034605)|part_of(GO:1903936)|part_of(GO:0071417)|has_input(UniProtKB:P11501)	UniProtKB:P38531
`

###gorule-0000046

The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

* total: 39
#### Messages
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:1332235	Nrf1	enables	GO:0042803	GO_REF:0000024	ISS	UniProtKB:Q90979	F	nuclear respiratory factor 1	D6Ertd415e	protein	NCBITaxon:10090	20150422	AgBase		MGI:MGI:1332235
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P32394	HMOX1	enables	GO:0042803	GO_REF:0000024	ISS	UniProtKB:P09601	F	Heme oxygenase 1	HMOX1	protein	taxon:9823	20160106	AgBase		UniProtKB:P32394
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q16656	NRF1	enables	GO:0042803	GO_REF:0000024	ISS	UniProtKB:Q90979	F	Nuclear respiratory factor 1	NRF1	protein	taxon:9606	20150422	AgBase		UniProtKB:Q16656
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q16656	NRF1	enables	GO:0042803	GO_REF:0000024	ISS	UniProtKB:Q90979	F	Nuclear respiratory factor 1	NRF1	protein	taxon:9606	20150422	AgBase		UniProtKB:Q16656-4
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	A4FUX1	CIDEA	enables	GO:0042803	GO_REF:0000024	ISS	UniProtKB:O70302	F	Lipid transferase CIDEA	CIDEA	protein	taxon:9913	20160205	AgBase		UniProtKB:A4FUX1
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P00257	FDX1	enables	GO:0042803	PMID:12069587	IDA		F	Adrenodoxin, mitochondrial	FDX1|ADX	protein	taxon:9913	20060308	AgBase		UniProtKB:P00257
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P02663	CSN1S2	enables	GO:0042803	PMID:8186264	IDA		F	Alpha-S2-casein	CSN1S2	protein	taxon:9913	20150522	AgBase		UniProtKB:P02663
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P02666	CSN2	enables	GO:0042803	PMID:8186264	IDA		F	Beta-casein	CSN2	protein	taxon:9913	20150522	AgBase		UniProtKB:P02666
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P18203	FKBP1A	enables	GO:0042803	PMID:11341768	ISA	UniProtKB:P26883	F	Peptidyl-prolyl cis-trans isomerase FKBP1A	FKBP1A|FKBP1	protein	taxon:9913	20140902	AgBase		UniProtKB:P18203
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P21214	TGFB2	enables	GO:0042803	GO_REF:0000024	ISS	UniProtKB:P61812	F	Transforming growth factor beta-2 proprotein	TGFB2	protein	taxon:9913	20141202	AgBase		UniProtKB:P21214
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P41541	USO1	involved_in	GO:0051260	PMID:1512287	IDA		P	General vesicular transport factor p115	USO1|VDP	protein	taxon:9913	20150201	AgBase		UniProtKB:P41541
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P42917	INHBB	enables	GO:0042803	GO_REF:0000024	ISS	UniProtKB:P09529	F	Inhibin beta B chain	INHBB	protein	taxon:9913	20070131	AgBase		UniProtKB:P42917
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q28204	KCNMA1	involved_in	GO:0051260	PMID:8973172	ISA	UniProtKB:Q08460	P	Calcium-activated potassium channel subunit alpha-1	KCNMA1|KCNMA	protein	taxon:9913	20090416	AgBase		UniProtKB:Q28204
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q2KJ63	KLKB1	enables	GO:0042803	PMID:8186264	IDA		F	Plasma kallikrein	KLKB1	protein	taxon:9913	20150522	AgBase		UniProtKB:Q2KJ63
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q3B7N2	ACTN1	enables	GO:0042803	GO_REF:0000024	ISS	UniProtKB:P05094-2	F	Alpha-actinin-1	ACTN1	protein	taxon:9913	20150407	AgBase		UniProtKB:Q3B7N2
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q76LV2	HSP90AA1	enables	GO:0042803	GO_REF:0000024	ISS	UniProtKB:P07901	F	Heat shock protein HSP 90-alpha	HSP90AA1|HSP90A|HSPCA	protein	taxon:9913	20061006	AgBase		UniProtKB:Q76LV2
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	F1NNP2	TGFB2	enables	GO:0042803	GO_REF:0000024	ISS	UniProtKB:P61812	F	Transforming growth factor beta	TGFB2	protein	taxon:9031	20141202	AgBase		UniProtKB:F1NNP2
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	F1P0N0	SKIL	enables	GO:0042803	PMID:9927733	IMP		F	c-SKI SMAD4-binding domain-containing protein	SKIL	protein	taxon:9031	20150414	AgBase		UniProtKB:F1P0N0
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	F1P3Y2	RHO	enables	GO:0042803	PMID:2605226	IDA		F	Rhodopsin	RHO	protein	taxon:9031	20150604	AgBase		UniProtKB:F1P3Y2
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P02504	CRYAA	involved_in	GO:0051260	PMID:15135047	ISS	UniProtKB:P02489	P	Alpha-crystallin A chain	CRYAA	protein	taxon:9031	20140201	AgBase		UniProtKB:P02504
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P05094	ACTN1	enables	GO:0042803	PMID:8037676	IDA		F	Alpha-actinin-1	ACTN1	protein	taxon:9031	20150407	AgBase		UniProtKB:P05094
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P05094	ACTN1	enables	GO:0042803	PMID:8037676	IDA		F	Alpha-actinin-1	ACTN1	protein	taxon:9031	20150407	AgBase		UniProtKB:P05094-2
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P12003	VCL	enables	GO:0042803	PMID:8037676	IDA		F	Vinculin	VCL|VINC1	protein	taxon:9031	20150407	AgBase		UniProtKB:P12003
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P22328	RHO	enables	GO:0042803	PMID:2605226	IDA		F	Rhodopsin	RHO	protein	taxon:9031	20150604	AgBase		UniProtKB:P22328
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P22328	RHO	involved_in	GO:0070207	PMID:2605226	IDA		P	Rhodopsin	RHO	protein	taxon:9031	20150604	AgBase		UniProtKB:P22328
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P22329	P22329	enables	GO:0042803	PMID:2605226	IDA		F	Red-sensitive opsin		protein	taxon:9031	20150604	AgBase		UniProtKB:P22329
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P22329	P22329	involved_in	GO:0070207	PMID:2605226	IDA		P	Red-sensitive opsin		protein	taxon:9031	20150604	AgBase		UniProtKB:P22329
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P30371	TGFB2	enables	GO:0042803	PMID:10401723	ISA	UniProtKB:P61812	F	Transforming growth factor beta-2 proprotein	TGFB2	protein	taxon:9031	20090424	AgBase		UniProtKB:P30371
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P38529	HSF1	enables	GO:0042803	PMID:9716376	IDA		F	Heat shock factor protein 1	HSF1	protein	taxon:9031	20151228	AgBase		UniProtKB:P38529
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P38530	HSF2	enables	GO:0042803	PMID:9716376	IDA		F	Heat shock factor protein 2	HSF2	protein	taxon:9031	20151228	AgBase		UniProtKB:P38530
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P38531	HSF3	enables	GO:0042803	PMID:21813737	IDA		F	Heat shock factor protein 3	HSF3	protein	taxon:9031	20151224	AgBase		UniProtKB:P38531
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P38531	HSF3	enables	GO:0042803	PMID:9716376	IDA		F	Heat shock factor protein 3	HSF3	protein	taxon:9031	20151228	AgBase		UniProtKB:P38531
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P38531	HSF3	involved_in	GO:0070207	PMID:21813737	IDA		P	Heat shock factor protein 3	HSF3	protein	taxon:9031	20151224	AgBase		UniProtKB:P38531
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P49140	SKI	enables	GO:0042803	PMID:9927733	IMP		F	Ski oncogene	SKI	protein	taxon:9031	20150414	AgBase		UniProtKB:P49140
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q90ZK6	ACVR1	enables	GO:0042803	PMID:10885742	ISA	UniProtKB:Q04771	F	Activin receptor type-1	ACVR1	protein	taxon:9031	20090113	AgBase		UniProtKB:Q90ZK6
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q98953	S100A6	enables	GO:0042803	PMID:8925441	IDA		F	Protein S100-A6	S100A6	protein	taxon:9031	20150421	AgBase		UniProtKB:Q98953
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q9DG23	POPDC1	involved_in	GO:0051260	PMID:12815060	IDA		P	Popeye domain-containing protein 1	POPDC1|BVES|POP1	protein	taxon:9031	20150402	AgBase		UniProtKB:Q9DG23
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q9IA05	FZD4	enables	GO:0042803	PMID:11044615	ISO	UniProtKB:Q9ULV1	F	Frizzled-4	FZD4|FZ4	protein	taxon:9031	20120809	AgBase		UniProtKB:Q9IA05
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q28265	KCNMA1	involved_in	GO:0051260	PMID:8973172	ISA	UniProtKB:Q08460	P	Calcium-activated potassium channel subunit alpha-1	KCNMA1|KCNMA	protein	taxon:9615	20090416	AgBase		UniProtKB:Q28265
`

###gorule-0000061

Allowed gene product to term relations (gp2term)

* total: 1
#### Messages
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002325 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB	P67881	CYC	colocalizes_with	GO:0043293	PMID:12220121	IDA		C	Cytochrome c	CYC	protein	taxon:9031	20110427	AgBase		UniProtKB:P67881
`

###gorule-0000063

Annotations using ISS/ISA/ISO evidence should refer to a gene product (in the 'with' column)

* total: 1
#### Messages
* WARNING - Violates GO Rule:GORULE:0000063: Annotations using ISS/ISA/ISO evidence should refer to a gene product (in the 'with' column)--`UniProtKB	P31043	CD28	located_in	GO:0005886	PMID:19013189	ISS		C	T-cell-specific surface glycoprotein CD28 homolog	CD28	protein	taxon:9031	20140515	AgBase		UniProtKB:P31043
`

###gorule-0000065

Annotations to term that are candidates for obsoletion should be produce a warning

* total: 98
#### Messages
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1341830	Eif2ak3	involved_in	GO:0046777	PMID:12610133	IDA		P	eukaryotic translation initiation factor 2 alpha kinase 3	PERK	protein	NCBITaxon:10090	20141207	AgBase		MGI:MGI:1341830
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	A4L7N3	FOXO1	involved_in	GO:0018105	PMID:24280217	IDA		P	Forkhead box protein O1	FOXO1|FOXO1A	protein	taxon:9823	20141226	AgBase		UniProtKB:A4L7N3
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	A4L7N3	FOXO1	involved_in	GO:0018107	PMID:24280217	IDA		P	Forkhead box protein O1	FOXO1|FOXO1A	protein	taxon:9823	20141226	AgBase		UniProtKB:A4L7N3
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	A7LKB1	SIRT1	involved_in	GO:1901984	PMID:23313858	IMP		P	protein acetyllysine N-acetyltransferase	SIRT1	protein	taxon:9823	20151023	AgBase	occurs_in(CL:0002334),has_input(UniProtKB:Q9TUB2)	UniProtKB:A7LKB1
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	B2DCZ9	ARHGEF2	involved_in	GO:1904685	PMID:23389627	IMP		P	Rho guanine nucleotide exchange factor 2	ARHGEF2	protein	taxon:9823	20160116	AgBase	has_input(UniProtKB:O77636)	UniProtKB:B2DCZ9
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	F1RIT1	TRPV4	involved_in	GO:0001934	PMID:25681460	IMP		P	Ion transport domain-containing protein	TRPV4	protein	taxon:9823	20150730	AgBase	occurs_in(CL:0000706)	UniProtKB:F1RIT1
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	F1RIT1	TRPV4	involved_in	GO:0061098	PMID:22492652	IMP		P	Ion transport domain-containing protein	TRPV4	protein	taxon:9823	20150728	AgBase	occurs_in(UBERON:0001803),happens_during(GO:0071476)	UniProtKB:F1RIT1
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	F1RIT1	TRPV4	involved_in	GO:1903408	PMID:22492652	IMP		P	Ion transport domain-containing protein	TRPV4	protein	taxon:9823	20150728	AgBase	occurs_in(UBERON:0001803),happens_during(GO:0071476)	UniProtKB:F1RIT1
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	F1RME6	FOXO1	involved_in	GO:0018105	PMID:24280217	IDA		P	Forkhead box protein O1	FOXO1	protein	taxon:9823	20141226	AgBase		UniProtKB:F1RME6
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	F1RME6	FOXO1	involved_in	GO:0018107	PMID:24280217	IDA		P	Forkhead box protein O1	FOXO1	protein	taxon:9823	20141226	AgBase		UniProtKB:F1RME6
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	I3LVS7	RHOA	involved_in	GO:0060193	GO_REF:0000024	ISS	UniProtKB:P61586	P	Ras homolog family member A	RHOA	protein	taxon:9823	20150916	AgBase		UniProtKB:I3LVS7
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05207	PRKAR2A	involved_in	GO:2000480	PMID:22674394	IMP		P	cAMP-dependent protein kinase type II-alpha regulatory subunit	PRKAR2A	protein	taxon:9823	20150411	AgBase	occurs_in(CL:0000654)	UniProtKB:P05207
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q04745	IL4	involved_in	GO:0001934	PMID:24280217	IMP		P	Interleukin-4	IL4	protein	taxon:9823	20141226	AgBase	has_input(UniProtKB:A4L7N3)	UniProtKB:Q04745
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q6GUA6	Q6GUA6	involved_in	GO:0043406	PMID:24313324	IMP		P	Growth/differentiation factor 9		protein	taxon:9823	20141117	AgBase		UniProtKB:Q6GUA6
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q6GUA6	Q6GUA6	involved_in	GO:0045737	PMID:24313324	IMP		P	Growth/differentiation factor 9		protein	taxon:9823	20141117	AgBase		UniProtKB:Q6GUA6
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P08134	RHOC	involved_in	GO:0060193	PMID:19887681	IDA		P	Rho-related GTP-binding protein RhoC	RHOC|ARH9|ARHC	protein	taxon:9606	20150330	AgBase	has_input(UniProtKB:Q9FD10)	UniProtKB:P08134
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P61586	RHOA	involved_in	GO:0060193	PMID:19887681	IDA		P	Transforming protein RhoA	RHOA|ARH12|ARHA|RHO12	protein	taxon:9606	20150330	AgBase	has_input(UniProtKB:Q9FD10)	UniProtKB:P61586
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P61586	RHOA	involved_in	GO:0060193	PMID:22740689	IMP		P	Transforming protein RhoA	RHOA|ARH12|ARHA|RHO12	protein	taxon:9606	20150626	AgBase	has_input(UniProtKB:Q9FD10)	UniProtKB:P61586
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q14240	EIF4A2	involved_in	GO:1900260	PMID:11922617	IDA		P	Eukaryotic initiation factor 4A-II	EIF4A2|DDX2B|EIF4F	protein	taxon:9606	20141112	AgBase	has_input(UniProtKB:P27958-PRO_0000037577)	UniProtKB:Q14240
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9UBS4	DNAJB11	involved_in	GO:0032781	PMID:20335166	IDA		P	DnaJ homolog subfamily B member 11	DNAJB11|EDJ|ERJ3|HDJ9|PSEC0121|UNQ537/PRO1080	protein	taxon:9606	20150811	AgBase	has_input(UniProtKB:P11021)	UniProtKB:Q9UBS4
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	F1MHQ4	FABP4	involved_in	GO:0006469	GO_REF:0000024	ISS	UniProtKB:P04117	P	Cytosolic fatty-acid binding proteins domain-containing protein	FABP4	protein	taxon:9913	20160205	AgBase		UniProtKB:F1MHQ4
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	F1MNI5	PTGS2	involved_in	GO:0001934	PMID:21293029	IMP		P	Prostaglandin G/H synthase 2	PTGS2	protein	taxon:9913	20150915	AgBase	has_input(UniProtKB:P46196)|has_input(UniProtKB:E1B8P9)	UniProtKB:F1MNI5
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O62698	PTGS2	involved_in	GO:0001934	PMID:21293029	IMP		P	Prostaglandin G/H synthase 2	PTGS2|COX2	protein	taxon:9913	20150915	AgBase	has_input(UniProtKB:P46196)|has_input(UniProtKB:E1B8P9)	UniProtKB:O62698
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O62829	PPM1A	involved_in	GO:0006470	GO_REF:0000024	ISS	UniProtKB:P49443	P	Protein phosphatase 1A	PPM1A	protein	taxon:9913	20080103	AgBase		UniProtKB:O62829
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P05307	P4HB	involved_in	GO:0018401	GO_REF:0000024	ISS	UniProtKB:P07237	P	Protein disulfide-isomerase	P4HB|PDIA1	protein	taxon:9913	20061002	AgBase		UniProtKB:P05307
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P07455	IGF1	involved_in	GO:1903407	PMID:8713639	IMP		P	Insulin-like growth factor 1	IGF1|IGF-1	protein	taxon:9913	20150522	AgBase		UniProtKB:P07455
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P07455	IGF1	involved_in	GO:1903408	PMID:8713639	IMP		P	Insulin-like growth factor 1	IGF1|IGF-1	protein	taxon:9913	20160310	AgBase		UniProtKB:P07455
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P18203	FKBP1A	involved_in	GO:0000413	PMID:11341768	ISA	UniProtKB:P62942	P	Peptidyl-prolyl cis-trans isomerase FKBP1A	FKBP1A|FKBP1	protein	taxon:9913	20130311	AgBase		UniProtKB:P18203
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P18203	FKBP1A	involved_in	GO:0001933	PMID:11341768	ISA	UniProtKB:P26883	P	Peptidyl-prolyl cis-trans isomerase FKBP1A	FKBP1A|FKBP1	protein	taxon:9913	20090205	AgBase		UniProtKB:P18203
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P18203	FKBP1A	involved_in	GO:0060314	PMID:11341768	ISA	UniProtKB:P26883	P	Peptidyl-prolyl cis-trans isomerase FKBP1A	FKBP1A|FKBP1	protein	taxon:9913	20090205	AgBase		UniProtKB:P18203
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P18203	FKBP1A	involved_in	GO:0060314	PMID:11341768	ISA	UniProtKB:P62942	P	Peptidyl-prolyl cis-trans isomerase FKBP1A	FKBP1A|FKBP1	protein	taxon:9913	20090205	AgBase		UniProtKB:P18203
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P18203	FKBP1A	involved_in	GO:0060315	PMID:11341768	ISA	UniProtKB:P62942	P	Peptidyl-prolyl cis-trans isomerase FKBP1A	FKBP1A|FKBP1	protein	taxon:9913	20130311	AgBase		UniProtKB:P18203
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P20427	CSNK2A2	involved_in	GO:0006468	GO_REF:0000024	ISS	UniProtKB:O54833	P	Casein kinase II subunit alpha'	CSNK2A2	protein	taxon:9913	20070403	AgBase		UniProtKB:P20427
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P35507	CSNK1B	involved_in	GO:0018105	PMID:6952938	IDA		P	Casein kinase I isoform beta	CSNK1B	protein	taxon:9913	20150616	AgBase	occurs_in(UBERON:0001911),happens_during(GO:0007595)	UniProtKB:P35507
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P35508	CSNK1D	involved_in	GO:0018105	PMID:6952938	IDA		P	Casein kinase I isoform delta	CSNK1D|HCKID	protein	taxon:9913	20150616	AgBase	occurs_in(UBERON:0001911),happens_during(GO:0007595)	UniProtKB:P35508
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P45478	PPT1	involved_in	GO:0002084	GO_REF:0000024	ISS	UniProtKB:P50897	P	Palmitoyl-protein thioesterase 1	PPT1|CLN1|PPT	protein	taxon:9913	20070126	AgBase		UniProtKB:P45478
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P48035	FABP4	involved_in	GO:0006469	GO_REF:0000024	ISS	UniProtKB:P04117	P	Fatty acid-binding protein, adipocyte	FABP4	protein	taxon:9913	20160205	AgBase		UniProtKB:P48035
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P67827	CSNK1A1	involved_in	GO:0018105	PMID:6952938	IDA		P	Casein kinase I isoform alpha	CSNK1A1	protein	taxon:9913	20150616	AgBase	occurs_in(UBERON:0001911),happens_during(GO:0007595)	UniProtKB:P67827
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P67868	CSNK2B	involved_in	GO:0042325	PMID:19692545	IDA		P	Casein kinase II subunit beta	CSNK2B|CK2N	protein	taxon:9913	20160126	AgBase	has_input(UniProtKB:Q4VW77)	UniProtKB:P67868
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P68107	FKBP1B	NOT|involved_in	GO:0060314	PMID:12508222	ISA	UniProtKB:P68106	P	Peptidyl-prolyl cis-trans isomerase FKBP1B	FKBP1B|FKBP12.6	protein	taxon:9913	20090204	AgBase		UniProtKB:P68107
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P68107	FKBP1B	involved_in	GO:0000413	PMID:12508222	ISA	UniProtKB:P68106	P	Peptidyl-prolyl cis-trans isomerase FKBP1B	FKBP1B|FKBP12.6	protein	taxon:9913	20130311	AgBase		UniProtKB:P68107
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P68107	FKBP1B	involved_in	GO:0000413	PMID:12508222	ISA	UniProtKB:Q9Z2I2	P	Peptidyl-prolyl cis-trans isomerase FKBP1B	FKBP1B|FKBP12.6	protein	taxon:9913	20141103	AgBase		UniProtKB:P68107
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P68107	FKBP1B	involved_in	GO:0060314	PMID:12508222	ISA	UniProtKB:Q9Z2I2	P	Peptidyl-prolyl cis-trans isomerase FKBP1B	FKBP1B|FKBP12.6	protein	taxon:9913	20130311	AgBase		UniProtKB:P68107
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P68107	FKBP1B	involved_in	GO:0060315	PMID:12508222	ISA	UniProtKB:P68106	P	Peptidyl-prolyl cis-trans isomerase FKBP1B	FKBP1B|FKBP12.6	protein	taxon:9913	20130311	AgBase		UniProtKB:P68107
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q0VC49	CSNK1E	involved_in	GO:0018105	PMID:6952938	IDA		P	non-specific serine/threonine protein kinase	CSNK1E	protein	taxon:9913	20150616	AgBase	occurs_in(UBERON:0001911),happens_during(GO:0007595)	UniProtKB:Q0VC49
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q2HJ92	PRKRA	involved_in	GO:0006468	GO_REF:0000024	ISS	UniProtKB:Q9WTX2	P	Interferon-inducible double-stranded RNA-dependent protein kinase activator A	PRKRA	protein	taxon:9913	20070616	AgBase		UniProtKB:Q2HJ92
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q32PI1	VRK1	involved_in	GO:0006468	GO_REF:0000024	ISS	UniProtKB:Q80X41	P	Serine/threonine-protein kinase VRK1	VRK1	protein	taxon:9913	20061011	AgBase		UniProtKB:Q32PI1
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q32PI1	VRK1	involved_in	GO:0046777	GO_REF:0000024	ISS	UniProtKB:Q80X41	P	Serine/threonine-protein kinase VRK1	VRK1	protein	taxon:9913	20061011	AgBase		UniProtKB:Q32PI1
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q3ZBH9	MCM7	involved_in	GO:0042325	GO_REF:0000024	ISS	UniProtKB:P33993	P	DNA replication licensing factor MCM7	MCM7	protein	taxon:9913	20080201	AgBase		UniProtKB:Q3ZBH9
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q58CP9	STIM1	involved_in	GO:0032237	GO_REF:0000024	ISS	UniProtKB:Q13586	P	Stromal interaction molecule 1	STIM1	protein	taxon:9913	20070226	AgBase		UniProtKB:Q58CP9
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q5E9Y0	CDK2	involved_in	GO:0006468	GO_REF:0000024	ISS	UniProtKB:P97377	P	Cyclin-dependent kinase 2	CDK2|CDKN2	protein	taxon:9913	20071004	AgBase		UniProtKB:Q5E9Y0
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`Xenbase	XB-GENE-17341940	fkbp1b.S	acts_upstream_of_or_within	GO:0060314	PMID:9857007	IMP		P	FKBP prolyl isomerase 1B S homeolog	fkbp12.6|fkbp1l|otk4|pkbp1l|PPIase|xfkbp1b	protein	taxon:8355	20090311	AgBase		
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`Xenbase	XB-GENE-5836974	fkbp1a.L	acts_upstream_of_or_within	GO:0000413	PMID:11341768	ISA	UniProtKB:P18203	P	FKBP prolyl isomerase 1A L homeolog	fkbp1|fkbp 12|fkbp-12|pkc12|pkci2|ppiase|xfkbp1a	protein	taxon:8355	20130311	AgBase		
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`Xenbase	XB-GENE-5836974	fkbp1a.L	acts_upstream_of_or_within	GO:0000413	PMID:11341768	ISA	UniProtKB:P62942	P	FKBP prolyl isomerase 1A L homeolog	fkbp1|fkbp 12|fkbp-12|pkc12|pkci2|ppiase|xfkbp1a	protein	taxon:8355	20130311	AgBase		
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`Xenbase	XB-GENE-5836974	fkbp1a.L	acts_upstream_of_or_within	GO:0001933	PMID:11341768	ISA	UniProtKB:P26883	P	FKBP prolyl isomerase 1A L homeolog	fkbp1|fkbp 12|fkbp-12|pkc12|pkci2|ppiase|xfkbp1a	protein	taxon:8355	20090205	AgBase		
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`Xenbase	XB-GENE-5836974	fkbp1a.L	acts_upstream_of_or_within	GO:0060314	PMID:11341768	ISA	UniProtKB:P26883	P	FKBP prolyl isomerase 1A L homeolog	fkbp1|fkbp 12|fkbp-12|pkc12|pkci2|ppiase|xfkbp1a	protein	taxon:8355	20090205	AgBase		
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`Xenbase	XB-GENE-5836974	fkbp1a.L	acts_upstream_of_or_within	GO:0060314	PMID:11341768	ISA	UniProtKB:P62942	P	FKBP prolyl isomerase 1A L homeolog	fkbp1|fkbp 12|fkbp-12|pkc12|pkci2|ppiase|xfkbp1a	protein	taxon:8355	20090205	AgBase		
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`Xenbase	XB-GENE-5836974	fkbp1a.L	acts_upstream_of_or_within	GO:0060314	PMID:9857007	IMP		P	FKBP prolyl isomerase 1A L homeolog	fkbp1|fkbp 12|fkbp-12|pkc12|pkci2|ppiase|xfkbp1a	protein	taxon:8355	20090311	AgBase		
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`Xenbase	XB-GENE-5836974	fkbp1a.L	acts_upstream_of_or_within	GO:0060315	PMID:11341768	ISA	UniProtKB:P62942	P	FKBP prolyl isomerase 1A L homeolog	fkbp1|fkbp 12|fkbp-12|pkc12|pkci2|ppiase|xfkbp1a	protein	taxon:8355	20130311	AgBase		
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`Xenbase	XB-GENE-865153	fzd4.S	acts_upstream_of_or_within	GO:0043507	PMID:11044615	ISO	UniProtKB:Q61088	P	frizzled class receptor 4 S homeolog	frizzled 4|frizzled-4|frizzled4|Fz-4|Fz4|LOC108708760|Xfz4	protein	taxon:8355	20120809	AgBase		
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	F1N9Y5	SYK	involved_in	GO:0018108	PMID:11434777	IMP		P	Tyrosine-protein kinase SYK	SYK|RCJMB04_19o18	protein	taxon:9031	20110407	AgBase		UniProtKB:F1N9Y5
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	F1NHL2	CAND1	involved_in	GO:0043086	GO_REF:0000024	ISS	UniProtKB:Q86VP6	P	TATA-binding protein interacting (TIP20) domain-containing protein	CAND1	protein	taxon:9031	20080204	AgBase		UniProtKB:F1NHL2
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	F1P4G3	HIPK2	involved_in	GO:0006468	GO_REF:0000024	ISS	UniProtKB:Q9QZR5	P	non-specific serine/threonine protein kinase	HIPK2	protein	taxon:9031	20061117	AgBase		UniProtKB:F1P4G3
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O42422	EPHA7	involved_in	GO:0016310	GO_REF:0000024	ISS	UniProtKB:P54759	P	Ephrin type-A receptor 7	EPHA7|CEK11	protein	taxon:9031	20060411	AgBase		UniProtKB:O42422
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P07341	ALDOB	involved_in	GO:0032781	PMID:2985560	ISA	UniProtKB:P05062	P	Fructose-bisphosphate aldolase B	ALDOB	protein	taxon:9031	20090306	AgBase		UniProtKB:P07341
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P12957	CALD1	involved_in	GO:1903611	PMID:8925441	IMP		P	Caldesmon	CALD1|CAD	protein	taxon:9031	20150421	AgBase		UniProtKB:P12957
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P30371	TGFB2	involved_in	GO:0006468	PMID:10401723	ISA	UniProtKB:P61812	P	Transforming growth factor beta-2 proprotein	TGFB2	protein	taxon:9031	20091203	AgBase		UniProtKB:P30371
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P30371	TGFB2	involved_in	GO:0032147	PMID:10401723	ISA	UniProtKB:P61812	P	Transforming growth factor beta-2 proprotein	TGFB2	protein	taxon:9031	20090424	AgBase		UniProtKB:P30371
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P49416	SDC4	involved_in	GO:0061098	GO_REF:0000024	ISS	UniProtKB:G3UNU3	P	Syndecan-4	SDC4	protein	taxon:9031	20150616	AgBase		UniProtKB:P49416
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P49416	SDC4	involved_in	GO:0061098	GO_REF:0000024	ISS	UniProtKB:Q5I5K4	P	Syndecan-4	SDC4	protein	taxon:9031	20150616	AgBase		UniProtKB:P49416
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P49416	SDC4	involved_in	GO:0090630	GO_REF:0000024	ISS	UniProtKB:G3UNU3	P	Syndecan-4	SDC4	protein	taxon:9031	20141211	AgBase		UniProtKB:P49416
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P49416	SDC4	involved_in	GO:0090630	GO_REF:0000024	ISS	UniProtKB:Q5I5K4	P	Syndecan-4	SDC4	protein	taxon:9031	20141211	AgBase		UniProtKB:P49416
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q00649	HSPB1	involved_in	GO:0006469	PMID:15135047	ISS	UniProtKB:P14602	P	Heat shock protein beta-1	HSPB1	protein	taxon:9031	20140201	AgBase		UniProtKB:Q00649
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q00649	HSPB1	involved_in	GO:0071901	PMID:15135047	ISS	UniProtKB:P14602	P	Heat shock protein beta-1	HSPB1	protein	taxon:9031	20140201	AgBase		UniProtKB:Q00649
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q00944	PTK2	involved_in	GO:0031953	PMID:23393139	IMP		P	Focal adhesion kinase 1	PTK2|FAK|FAK1	protein	taxon:9031	20160114	AgBase		UniProtKB:Q00944
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q00944	PTK2	involved_in	GO:0046777	PMID:10409118	IDA		P	Focal adhesion kinase 1	PTK2|FAK|FAK1	protein	taxon:9031	20160114	AgBase	occurs_in(UBERON:0001112),occurs_in(CL:0000187)|occurs_in(CL:0002372),occurs_in(CL:0000515)	UniProtKB:Q00944
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q00944	PTK2	involved_in	GO:0061098	PMID:15340073	IMP		P	Focal adhesion kinase 1	PTK2|FAK|FAK1	protein	taxon:9031	20160113	AgBase		UniProtKB:Q00944
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q05876	FYN	involved_in	GO:0018108	GO_REF:0000024	ISS	UniProtKB:Q62844	P	Tyrosine-protein kinase Fyn	FYN	protein	taxon:9031	20061003	AgBase		UniProtKB:Q05876
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q06900	ChALK5	involved_in	GO:0006468	PMID:10885742	ISA	UniProtKB:P36897	P	TGF-beta receptor type-1	ChALK5	protein	taxon:9031	20091203	AgBase		UniProtKB:Q06900
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q06900	ChALK5	involved_in	GO:0018105	PMID:10885742	ISA	UniProtKB:P36897	P	TGF-beta receptor type-1	ChALK5	protein	taxon:9031	20130311	AgBase		UniProtKB:Q06900
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q06900	ChALK5	involved_in	GO:0018107	PMID:10885742	ISA	UniProtKB:P36897	P	TGF-beta receptor type-1	ChALK5	protein	taxon:9031	20130311	AgBase		UniProtKB:Q06900
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q5ZK05	TOLLIP	involved_in	GO:0016310	GO_REF:0000024	ISS	UniProtKB:Q9H0E2	P	Toll-interacting protein	TOLLIP|RCJMB04_14a3	protein	taxon:9031	20060524	AgBase		UniProtKB:Q5ZK05
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q5ZK05	TOLLIP	involved_in	GO:0016310	PMID:12814703	ISA	UniProtKB:Q9H0E2	P	Toll-interacting protein	TOLLIP|RCJMB04_14a3	protein	taxon:9031	20111007	AgBase		UniProtKB:Q5ZK05
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q703P0	CRH	NOT|involved_in	GO:0051341	PMID:18786646	IDA		P	Corticotropin-releasing factor domain-containing protein	CRH	protein	taxon:9031	20130312	AgBase		UniProtKB:Q703P0
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q703P0	CRH	NOT|involved_in	GO:2000983	PMID:18786646	IDA		P	Corticotropin-releasing factor domain-containing protein	CRH	protein	taxon:9031	20130312	AgBase		UniProtKB:Q703P0
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q90611	MMP2	involved_in	GO:0001933	PMID:17604018	IMP		P	72 kDa type IV collagenase	MMP2	protein	taxon:9031	20160129	AgBase	occurs_in(CL:0000134)	UniProtKB:Q90611
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q90694	CDC42	involved_in	GO:0045860	GO_REF:0000024	ISS	UniProtKB:P40793	P	Cell division control protein 42 homolog	CDC42	protein	taxon:9031	20060411	AgBase		UniProtKB:Q90694
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q90738	AFAP1	involved_in	GO:0018108	PMID:15485829	IGI	UniProtKB:P00523	P	Actin filament-associated protein 1	AFAP1	protein	taxon:9031	20100802	AgBase		UniProtKB:Q90738
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q90738	AFAP1	involved_in	GO:0018109	PMID:15485829	IMP		P	Actin filament-associated protein 1	AFAP1	protein	taxon:9031	20100802	AgBase		UniProtKB:Q90738
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q90999	TGFBR2	involved_in	GO:0006468	PMID:8167376	ISA	UniProtKB:P37173	P	TGF-beta receptor type-2	TGFBR2	protein	taxon:9031	20130311	AgBase		UniProtKB:Q90999
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q90ZK6	ACVR1	involved_in	GO:0006468	PMID:10885742	ISA	UniProtKB:Q04771	P	Activin receptor type-1	ACVR1	protein	taxon:9031	20090113	AgBase		UniProtKB:Q90ZK6
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q90ZK6	ACVR1	involved_in	GO:0018107	PMID:10885742	ISA	UniProtKB:Q04771	P	Activin receptor type-1	ACVR1	protein	taxon:9031	20130311	AgBase		UniProtKB:Q90ZK6
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q91035	SHH	involved_in	GO:0010694	PMID:9268735	IDA		P	Sonic hedgehog protein	SHH	protein	taxon:9031	20150522	AgBase		UniProtKB:Q91035-PRO_0000013218
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q98938	IHH	involved_in	GO:0010694	PMID:19252479	IMP		P	Indian hedgehog protein	IHH	protein	taxon:9031	20150522	AgBase	occurs_in(UBERON:0010328)	UniProtKB:Q98938
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q98938	IHH	involved_in	GO:0010694	PMID:9268735	IDA		P	Indian hedgehog protein	IHH	protein	taxon:9031	20150522	AgBase		UniProtKB:Q98938
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9IA05	FZD4	involved_in	GO:0043507	PMID:11044615	ISO	UniProtKB:Q61088	P	Frizzled-4	FZD4|FZ4	protein	taxon:9031	20120809	AgBase		UniProtKB:Q9IA05
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9YGL6	PALM	involved_in	GO:0007194	PMID:9813098	ISS	UniProtKB:Q9Z0P4	P	Paralemmin-1	PALM	protein	taxon:9031	20140201	AgBase		UniProtKB:Q9YGL6
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O02812	MAPK14	involved_in	GO:0016310	PMID:9688607	IDA		P	Mitogen-activated protein kinase 14	MAPK14|CSBP1|CSBP2	protein	taxon:9615	20080711	AgBase		UniProtKB:O02812
`