# GORULE violations assigned by BHF-UCL

## SUMMARY

This report generated on 2026-05-21

## Contents

[gorule-0000001](#gorule-0000001)[GAF lines are parsed according to GAF 2.2 specifications]{}

[gorule-0000005](#gorule-0000005)[IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations are not allowed for direct annotations to 'protein binding ; GO:0005515 or GO:0005488 binding'']{}

[gorule-0000008](#gorule-0000008)[No annotations should be made to uninformative high level terms]{}

[gorule-0000013](#gorule-0000013)[Taxon-appropriate annotation check]{}

[gorule-0000015](#gorule-0000015)[Dual species taxon check]{}

[gorule-0000016](#gorule-0000016)[With/From: IC annotations require a With/From GO ID]{}

[gorule-0000020](#gorule-0000020)[Automatic repair of annotations to merged or obsoleted terms]{}

[gorule-0000039](#gorule-0000039)[Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants]{}

[gorule-0000046](#gorule-0000046)[The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.]{}

[gorule-0000061](#gorule-0000061)[Allowed gene product to term relations (gp2term)]{}

[gorule-0000065](#gorule-0000065)[Annotations to term that are candidates for obsoletion should be produce a warning]{}

## MESSAGES

###gorule-0000001

GAF lines are parsed according to GAF 2.2 specifications

* total: 9
#### Messages
* WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral	URS000075C8FA_9606	URS000075C8FA_9606	contributes_to	GO:0003968	PMID:19701182	IDA		F	Homo sapiens (human) RNA component of mitochondrial RNA processing endoribonuclease (RMRP)		enzymatic_RNA	taxon:9606	20150218	BHF-UCL		`
* WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral	URS000075C8FA_9606	URS000075C8FA_9606	contributes_to	GO:0098680	PMID:19701182	IDA		F	Homo sapiens (human) RNA component of mitochondrial RNA processing endoribonuclease (RMRP)		enzymatic_RNA	taxon:9606	20170213	BHF-UCL		`
* WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral	URS000075C8FA_9606	URS000075C8FA_9606	enables	GO:0005515	PMID:19701182	IPI	UniProtKB:O14746	F	Homo sapiens (human) RNA component of mitochondrial RNA processing endoribonuclease (RMRP)		enzymatic_RNA	taxon:9606	20241115	BHF-UCL		`
* WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral	URS000075C8FA_9606	URS000075C8FA_9606	enables	GO:0070182	PMID:19701182	IPI	UniProtKB:O14746	F	Homo sapiens (human) RNA component of mitochondrial RNA processing endoribonuclease (RMRP)		enzymatic_RNA	taxon:9606	20151117	BHF-UCL		`
* WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral	URS000075C8FA_9606	URS000075C8FA_9606	involved_in	GO:0001172	PMID:19701182	IDA		P	Homo sapiens (human) RNA component of mitochondrial RNA processing endoribonuclease (RMRP)		enzymatic_RNA	taxon:9606	20150218	BHF-UCL		`
* WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral	URS000075C8FA_9606	URS000075C8FA_9606	involved_in	GO:0030422	PMID:19701182	IDA		P	Homo sapiens (human) RNA component of mitochondrial RNA processing endoribonuclease (RMRP)		enzymatic_RNA	taxon:9606	20150219	BHF-UCL		`
* WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral	URS000075C8FA_9606	URS000075C8FA_9606	involved_in	GO:0140745	PMID:19701182	IDA		P	Homo sapiens (human) RNA component of mitochondrial RNA processing endoribonuclease (RMRP)		enzymatic_RNA	taxon:9606	20220604	BHF-UCL		`
* WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral	URS000075C8FA_9606	URS000075C8FA_9606	located_in	GO:0005739	PMID:19701182	TAS		C	Homo sapiens (human) RNA component of mitochondrial RNA processing endoribonuclease (RMRP)		enzymatic_RNA	taxon:9606	20150219	BHF-UCL		`
* WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral	URS000075C8FA_9606	URS000075C8FA_9606	part_of	GO:1990572	PMID:19701182	IMP		C	Homo sapiens (human) RNA component of mitochondrial RNA processing endoribonuclease (RMRP)		enzymatic_RNA	taxon:9606	20150218	BHF-UCL		`

###gorule-0000005

IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations are not allowed for direct annotations to 'protein binding ; GO:0005515 or GO:0005488 binding''

* total: 8
#### Messages
* WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`MGI	MGI:1277959	Dlg4	enables	GO:0005515	GO_REF:0000024	ISS	UniProtKB:P31016	F	discs large MAGUK scaffold protein 4	Dlgh4|PSD-95|PSD95|SAP90|SAP90A	protein	NCBITaxon:10090	20131017	BHF-UCL		MGI:MGI:1277959
`
* WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`MGI	MGI:3613677	Shank1	enables	GO:0005515	GO_REF:0000024	ISS	UniProtKB:Q9WV48	F	SH3 and multiple ankyrin repeat domains 1		protein	NCBITaxon:10090	20131017	BHF-UCL		MGI:MGI:3613677
`
* WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB	Q92974	ARHGEF2	enables	GO:0005515	GO_REF:0000024	ISS	UniProtKB:Q865S3	F	Rho guanine nucleotide exchange factor 2	ARHGEF2|KIAA0651|LFP40	protein	taxon:9606	20210910	BHF-UCL		UniProtKB:Q92974
`
* WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB	Q9BYB0	SHANK3	enables	GO:0005515	GO_REF:0000024	ISS	UniProtKB:Q4ACU6	F	SH3 and multiple ankyrin repeat domains protein 3	SHANK3|KIAA1650|PROSAP2|PSAP2	protein	taxon:9606	20110218	BHF-UCL		UniProtKB:Q9BYB0
`
* WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB	Q9BYB0	SHANK3	enables	GO:0005515	GO_REF:0000024	ISS	UniProtKB:Q9JLU4	F	SH3 and multiple ankyrin repeat domains protein 3	SHANK3|KIAA1650|PROSAP2|PSAP2	protein	taxon:9606	20131017	BHF-UCL		UniProtKB:Q9BYB0
`
* WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB	Q9NQC8	IFT46	enables	GO:0005515	GO_REF:0000024	ISS	UniProtKB:A2T2X4	F	Intraflagellar transport protein 46 homolog	IFT46|C11orf2|C11orf60	protein	taxon:9606	20110314	BHF-UCL		UniProtKB:Q9NQC8
`
* WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB	Q9Y366	IFT52	enables	GO:0005515	GO_REF:0000024	ISS	UniProtKB:Q946G4	F	Intraflagellar transport protein 52 homolog	IFT52|C20orf9|NGD5|CGI-53	protein	taxon:9606	20110314	BHF-UCL		UniProtKB:Q9Y366
`
* WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB	Q9Y566	SHANK1	enables	GO:0005515	GO_REF:0000024	ISS	UniProtKB:Q9WV48	F	SH3 and multiple ankyrin repeat domains protein 1	SHANK1	protein	taxon:9606	20131017	BHF-UCL		UniProtKB:Q9Y566
`

###gorule-0000008

No annotations should be made to uninformative high level terms

* total: 9
#### Messages
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI	MGI:1858622	Vamp5	located_in	GO:0031090	PMID:9725904	IDA		C	vesicle-associated membrane protein 5	Camp	protein	NCBITaxon:10090	20140415	BHF-UCL	part_of(CL:0002372),part_of(GO:0031410)	MGI:MGI:1858622
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI	MGI:96612	Itgb3	involved_in	GO:0048858	PMID:16995821	IC	GO:0005178	P	integrin beta 3	CD61|platelet glycoprotein IIIa  (GP3A)	protein	NCBITaxon:10090	20110218	BHF-UCL		MGI:MGI:96612
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	O15530	PDPK1	located_in	GO:0042995	PMID:22454520	IDA		C	3-phosphoinositide-dependent protein kinase 1	PDPK1|PDK1	protein	taxon:9606	20140512	BHF-UCL		UniProtKB:O15530
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	O95183	VAMP5	located_in	GO:0031090	GO_REF:0000024	ISS	UniProtKB:Q9Z2P8	C	Vesicle-associated membrane protein 5	VAMP5|HSPC191	protein	taxon:9606	20140415	BHF-UCL	part_of(CL:0002372),part_of(GO:0031410)	UniProtKB:O95183
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P08567	PLEK	involved_in	GO:0030030	PMID:9060471	IDA		P	Pleckstrin	PLEK|P47	protein	taxon:9606	20090305	BHF-UCL		UniProtKB:P08567
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P12036	NEFH	involved_in	GO:0030031	PMID:17498690	TAS		P	Neurofilament heavy polypeptide	NEFH|KIAA0845|NFH	protein	taxon:9606	20140304	BHF-UCL	occurs_in(GO:0030424)	UniProtKB:P12036
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P14174	MIF	involved_in	GO:0019752	PMID:12782713	IDA		P	Macrophage migration inhibitory factor	MIF|GLIF|MMIF	protein	taxon:9606	20091216	BHF-UCL		UniProtKB:P14174
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P19174	PLCG1	located_in	GO:0042995	PMID:22454520	IDA		C	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	PLCG1|PLC1	protein	taxon:9606	20140512	BHF-UCL		UniProtKB:P19174
`
* WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB	P27708	CAD	located_in	GO:0042995	GO_REF:0000024	ISS	UniProtKB:A0A8I5ZMM2	C	Multifunctional protein CAD	CAD	protein	taxon:9606	20250718	BHF-UCL		UniProtKB:P27708
`

###gorule-0000013

Taxon-appropriate annotation check

* total: 3
#### Messages
* ERROR - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	Q5T5C0	STXBP5	enables	GO:0017075	GO_REF:0000024	ISS	UniProtKB:Q8K400	F	Syntaxin-binding protein 5	STXBP5|LLGL3	protein	taxon:9606	20110401	BHF-UCL		UniProtKB:Q5T5C0
`
* WARNING - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	O95477	ABCA1	enables	GO:0019905	PMID:15469992	IPI	UniProtKB:Q86Y82	F	Phospholipid-transporting ATPase ABCA1	ABCA1|ABC1|CERP	protein	taxon:9606	20120102	BHF-UCL		UniProtKB:O95477
`
* WARNING - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`UniProtKB	Q5T7P8	SYT6	enables	GO:0019905	PMID:7791877	IDA		F	Synaptotagmin-6	SYT6	protein	taxon:9606	20110623	BHF-UCL		UniProtKB:Q5T7P8
`

###gorule-0000015

Dual species taxon check

* total: 2
#### Messages
* WARNING - Violates GO Rule:GORULE:0000015: Dual species taxon check--`UniProtKB	P46934	NEDD4	acts_upstream_of	GO:0046755	PMID:15126635	IMP		P	E3 ubiquitin-protein ligase NEDD4	NEDD4|KIAA0093|NEDD4-1|RPF1|PIG53	protein	taxon:9606|taxon:11926	20200203	BHF-UCL		UniProtKB:P46934
`
* WARNING - Violates GO Rule:GORULE:0000015: Dual species taxon check--`UniProtKB	Q92692	NECTIN2	involved_in	GO:0019064	PMID:12915581	IDA		P	Nectin-2	NECTIN2|HVEB|PRR2|PVRL2	protein	taxon:9606|taxon:10310	20081128	BHF-UCL		UniProtKB:Q92692
`

###gorule-0000016

With/From: IC annotations require a With/From GO ID

* total: 5
#### Messages
* WARNING - Violates GO Rule:GORULE:0000016: All IC annotations should include a GO ID in the "With/From" column that is also different from the entry in the "GO ID" column--`MGI	MGI:97362	Nos3	located_in	GO:0005737	PMID:11732991	IC	GO:0005737	C	nitric oxide synthase 3, endothelial cell	2310065A03Rik|Nos-3|eNOS|ecNOS	protein	NCBITaxon:10090	20180821	BHF-UCL	part_of(CL:0000115),part_of(UBERON:0011742),existence_overlaps(GO:0003180)	MGI:MGI:97362
`
* WARNING - Violates GO Rule:GORULE:0000016: All IC annotations should include a GO ID in the "With/From" column that is also different from the entry in the "GO ID" column--`UniProtKB	P14859	POU2F1	enables	GO:0001228	PMID:25802280	IC		F	POU domain, class 2, transcription factor 1	POU2F1|OCT1|OTF1	protein	taxon:9606	20220817	BHF-UCL	part_of(GO:1902895),has_input(RNAcentral:URS00001DC04F_9606)	UniProtKB:P14859
`
* WARNING - Violates GO Rule:GORULE:0000016: All IC annotations should include a GO ID in the "With/From" column that is also different from the entry in the "GO ID" column--`UniProtKB	P14859	POU2F1	involved_in	GO:1902895	PMID:25802280	IC		P	POU domain, class 2, transcription factor 1	POU2F1|OCT1|OTF1	protein	taxon:9606	20220817	BHF-UCL	has_input(RNAcentral:URS00001DC04F_9606)	UniProtKB:P14859
`
* WARNING - Violates GO Rule:GORULE:0000016: All IC annotations should include a GO ID in the "With/From" column that is also different from the entry in the "GO ID" column--`UniProtKB	P55317	FOXA1	enables	GO:0001228	PMID:25802280	IC		F	Hepatocyte nuclear factor 3-alpha	FOXA1|HNF3A|TCF3A	protein	taxon:9606	20220817	BHF-UCL	has_input(RNAcentral:URS00001DC04F_9606),part_of(GO:1902895)	UniProtKB:P55317
`
* WARNING - Violates GO Rule:GORULE:0000016: All IC annotations should include a GO ID in the "With/From" column that is also different from the entry in the "GO ID" column--`UniProtKB	P55317	FOXA1	involved_in	GO:1902895	PMID:25802280	IC		P	Hepatocyte nuclear factor 3-alpha	FOXA1|HNF3A|TCF3A	protein	taxon:9606	20220817	BHF-UCL	has_input(RNAcentral:URS00001DC04F_9606)	UniProtKB:P55317
`

###gorule-0000020

Automatic repair of annotations to merged or obsoleted terms

* total: 11
#### Messages
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	Q9NQR4	NIT2	involved_in	GO:0006528	PMID:22674578	IDA		P	Omega-amidase NIT2	NIT2|CUA002	protein	taxon:9606	20140516	BHF-UCL		UniProtKB:Q9NQR4
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI	MGI:1860485	Plek	involved_in	GO:0006904	PMID:19190246	IMP		P	pleckstrin	2010300B13Rik	protein	NCBITaxon:10090	20090325	BHF-UCL		MGI:MGI:1860485
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	P08567	PLEK	involved_in	GO:0006904	GO_REF:0000024	ISS	UniProtKB:Q9JHK5	P	Pleckstrin	PLEK|P47	protein	taxon:9606	20090325	BHF-UCL		UniProtKB:P08567
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	P61006	RAB8A	involved_in	GO:0006904	PMID:17574030	IDA		P	Ras-related protein Rab-8A	RAB8A|MEL|RAB8	protein	taxon:9606	20080521	BHF-UCL		UniProtKB:P61006
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI	MGI:1346013	Popdc1	involved_in	GO:0048278	PMID:24048452	IMP		P	popeye domain cAMP effector 1	Bves|popeye 1	protein	NCBITaxon:10090	20141128	BHF-UCL	occurs_in(UBERON:0002348)	MGI:MGI:1346013
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI	MGI:2384590	Ndrg4	involved_in	GO:0048278	PMID:24048452	IMP		P	N-myc downstream regulated gene 4	D8Bwg1337e|Ndr1-rs|Ndr4|SMAP-8	protein	NCBITaxon:10090	20141128	BHF-UCL	occurs_in(UBERON:0002348)	MGI:MGI:2384590
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	P51636	CAV2	involved_in	GO:0048278	PMID:12743374	IDA		P	Caveolin-2	CAV2	protein	taxon:9606	20080214	BHF-UCL		UniProtKB:P51636
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI	MGI:1352464	Nr1h4	enables	GO:0001228	PMID:21757002	IDA		F	nuclear receptor subfamily 1, group H, member 4	FXR|Fxr|HRR1|RIP14|Rxrip14	protein	NCBITaxon:10090	20250924	BHF-UCL	has_input(UniProtKB:Q8R4H7),causally_upstream_of(GO:0019627),part_of(GO:1903413),part_of(GO:2000211)	MGI:MGI:1352464
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	Q96RI1	NR1H4	enables	GO:0001228	PMID:21757002	IDA		F	Bile acid receptor	NR1H4|BAR|FXR|HRR1|RIP14	protein	taxon:9606	20250924	BHF-UCL	has_input(UniProtKB:Q8N159),causally_upstream_of(GO:0019627),part_of(GO:1903413),part_of(GO:2000211)	UniProtKB:Q96RI1
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`RGD	3267	Pck1	involved_in	GO:0046327	PMID:4186849	IDA		P	phosphoenolpyruvate carboxykinase 1		protein	NCBITaxon:10116	20080424	BHF-UCL		RGD:3267
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB	P35558	PCK1	involved_in	GO:0046327	GO_REF:0000024	ISS	UniProtKB:P07379	P	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	PCK1|PEPCK1	protein	taxon:9606	20080424	BHF-UCL		UniProtKB:P35558
`

###gorule-0000039

Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants

* total: 1
#### Messages
* ERROR - Violates GO Rule:GORULE:0000039: Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants--`ComplexPortal	CPX-19	tert-terc_mouse	part_of	GO:0000333	PMID:16037417	IMP		C	Telomerase catalytic core complex	2xTert:2xTerc	protein_complex	taxon:10090	20150217	BHF-UCL		
`

###gorule-0000046

The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

* total: 71
#### Messages
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:103577	Hand1	enables	GO:0042803	PMID:10924525	IPI	UniProtKB:Q64279	F	heart and neural crest derivatives expressed 1	Ehand1|Hxt|Th1|Thing1|bHLHa27|eHAND	protein	NCBITaxon:10090	20090826	BHF-UCL		MGI:MGI:103577
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:103580	Hand2	enables	GO:0042803	PMID:11812799	IPI	UniProtKB:Q61039	F	heart and neural crest derivatives expressed 2	Ehand2|Hed|Thing2|bHLHa26|dHAND	protein	NCBITaxon:10090	20090827	BHF-UCL		MGI:MGI:103580
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:108050	Ext2	enables	GO:0042803	PMID:10639137	IDA		F	exostosin glycosyltransferase 2		protein	NCBITaxon:10090	20080228	BHF-UCL		MGI:MGI:108050
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:1195972	Terf2	enables	GO:0042803	PMID:9326950	IPI	UniProtKB:O35144	F	telomeric repeat binding factor 2	TRF2	protein	NCBITaxon:10090	20081216	BHF-UCL		MGI:MGI:1195972
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:1201414	Cer1	enables	GO:0042803	PMID:10748465	IDA		F	cerberus 1, DAN family BMP antagonist	Cerberus-like|Cerl|Cerl1|Cerr1|cer-1	protein	NCBITaxon:10090	20120213	BHF-UCL		MGI:MGI:1201414
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:1270845	Cidea	enables	GO:0042803	PMID:17080483	IDA		F	cell death-inducing DNA fragmentation factor, alpha subunit-like effector A		protein	NCBITaxon:10090	20071212	BHF-UCL		MGI:MGI:1270845
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:1277234	Tbx15	enables	GO:0042803	PMID:17584735	IPI	UniProtKB:O70306	F	T-box 15	Tbx14|Tbx8|de	protein	NCBITaxon:10090	20191030	BHF-UCL		MGI:MGI:1277234
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:1339753	Csf1	enables	GO:0042803	PMID:19017797	IPI	UniProtKB:P07141	F	colony stimulating factor 1 (macrophage)	BAP025|CSF-1|Csfm|M-CSF|colony-stimulating factor-1	protein	NCBITaxon:10090	20100311	BHF-UCL		MGI:MGI:1339753
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:1339758	Csf1r	enables	GO:0042803	PMID:19017797	IPI	UniProtKB:P09581	F	colony stimulating factor 1 receptor	CD115|CSF-1R|Csfmr|Fim-2|Fim2|Fms|M-CSFR	protein	NCBITaxon:10090	20090115	BHF-UCL		MGI:MGI:1339758
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:1351322	Mixl1	enables	GO:0042803	PMID:22164283	IPI	UniProtKB:Q9WUI0	F	Mix paired-like homeobox	Mml	protein	NCBITaxon:10090	20121029	BHF-UCL		MGI:MGI:1351322
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:1859544	Syt6	enables	GO:0042803	PMID:10531343	IDA		F	synaptotagmin VI	3110037A08Rik	protein	NCBITaxon:10090	20110630	BHF-UCL		MGI:MGI:1859544
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:1859546	Syt10	enables	GO:0042803	PMID:10531343	IDA		F	synaptotagmin X		protein	NCBITaxon:10090	20110630	BHF-UCL		MGI:MGI:1859546
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:1915050	Dgat2	enables	GO:0042803	PMID:21680734	IPI	UniProtKB:Q9DCV3	F	diacylglycerol O-acyltransferase 2	0610010B06Rik	protein	NCBITaxon:10090	20111130	BHF-UCL		MGI:MGI:1915050
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:1923615	Tbx18	enables	GO:0042803	PMID:17584735	IPI	UniProtKB:Q9EPZ6	F	T-box18	2810012F10Rik|2810404D13Rik	protein	NCBITaxon:10090	20191030	BHF-UCL		MGI:MGI:1923615
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:1930704	Bhlhe41	enables	GO:0042803	PMID:17487425	IPI	UniProtKB:Q99PV5	F	basic helix-loop-helix family, member e41	6430520M22Rik|Bhlhb3|DEC2|Sharp1	protein	NCBITaxon:10090	20111216	BHF-UCL		MGI:MGI:1930704
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:2149946	Gopc	enables	GO:0042803	PMID:11520064	IPI	UniProtKB:Q8BH60	F	golgi associated PDZ and coiled-coil motif containing	2210402P09Rik|GOPC1	protein	NCBITaxon:10090	20110330	BHF-UCL		MGI:MGI:2149946
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:2180781	Slc8b1	enables	GO:0042803	PMID:20018762	IPI	UniProtKB:Q925Q3	F	solute carrier family 8 (sodium/lithium/calcium exchanger), member B1	NCKX6|NCLX|Slc24a6	protein	NCBITaxon:10090	20140904	BHF-UCL	occurs_in(UBERON:0000948)|occurs_in(UBERON:0000955)	MGI:MGI:2180781
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:2442682	Slc30a8	enables	GO:0042803	PMID:19095428	IPI	UniProtKB:Q8BGG0	F	solute carrier family 30 (zinc transporter), member 8	C820002P14Rik|ZnT-8|ZnT8	protein	NCBITaxon:10090	20100128	BHF-UCL		MGI:MGI:2442682
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:95392	Eng	enables	GO:0042803	PMID:8194490	IPI	UniProtKB:Q63961	F	endoglin	CD105|Endo	protein	NCBITaxon:10090	20081107	BHF-UCL		MGI:MGI:95392
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:97361	Nos2	enables	GO:0042803	PMID:9271491	IDA		F	nitric oxide synthase 2, inducible	NOS-II|Nos-2|Nos2a|iNOS	protein	NCBITaxon:10090	20080725	BHF-UCL		MGI:MGI:97361
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:99665	Syt3	enables	GO:0042803	PMID:10531343	IDA		F	synaptotagmin III		protein	NCBITaxon:10090	20110630	BHF-UCL		MGI:MGI:99665
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`RGD	1565818	Slc8b1	enables	GO:0042803	PMID:20018762	IPI	UniProtKB:Q6AXS0	F	solute carrier family 8 member B1		protein	NCBITaxon:10116	20140904	BHF-UCL	occurs_in(UBERON:0000948)	RGD:1565818
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`RGD	2276	Casq2	enables	GO:0042803	PMID:20353949	IDA		F	calsequestrin 2		protein	NCBITaxon:10116	20120620	BHF-UCL		RGD:2276
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`RGD	61916	Fzd1	enables	GO:0042803	PMID:14688793	IPI	UniProtKB:Q08463	F	frizzled class receptor 1		protein	NCBITaxon:10116	20100803	BHF-UCL		RGD:61916
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	O14503	BHLHE40	enables	GO:0042803	PMID:15560782	IDA		F	Class E basic helix-loop-helix protein 40	BHLHE40|BHLHB2|DEC1|SHARP2|STRA13	protein	taxon:9606	20111114	BHF-UCL		UniProtKB:O14503
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	O14746	TERT	enables	GO:0042803	PMID:11432839	IDA		F	Telomerase reverse transcriptase	TERT|EST2|TCS1|TRT	protein	taxon:9606	20081219	BHF-UCL		UniProtKB:O14746
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	O43353	RIPK2	enables	GO:0042803	PMID:19337385	IDA		F	Receptor-interacting serine/threonine-protein kinase 2	RIPK2|CARDIAK|RICK|RIP2|UNQ277/PRO314/PRO34092	protein	taxon:9606	20110124	BHF-UCL		UniProtKB:O43353
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P01127	PDGFB	enables	GO:0042803	PMID:2836953	IDA		F	Platelet-derived growth factor subunit B	PDGFB|PDGF2|SIS	protein	taxon:9606	20080428	BHF-UCL		UniProtKB:P01127
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P02652	APOA2	enables	GO:0042803	PMID:17264082	IDA		F	Apolipoprotein A-II	APOA2	protein	taxon:9606	20080104	BHF-UCL		UniProtKB:P02652
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P04085	PDGFA	enables	GO:0042803	PMID:2836953	IDA		F	Platelet-derived growth factor subunit A	PDGFA|PDGF1	protein	taxon:9606	20080428	BHF-UCL		UniProtKB:P04085
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P04085	PDGFA	enables	GO:0042803	PMID:3754619	IDA		F	Platelet-derived growth factor subunit A	PDGFA|PDGF1	protein	taxon:9606	20080428	BHF-UCL		UniProtKB:P04085
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P06727	APOA4	enables	GO:0042803	PMID:1935934	IDA		F	Apolipoprotein A-IV	APOA4	protein	taxon:9606	20080107	BHF-UCL		UniProtKB:P06727
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P08567	PLEK	enables	GO:0042803	PMID:8694752	IDA		F	Pleckstrin	PLEK|P47	protein	taxon:9606	20090305	BHF-UCL		UniProtKB:P08567
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P08913	ADRA2A	enables	GO:0042803	PMID:16605244	IDA		F	Alpha-2A adrenergic receptor	ADRA2A|ADRA2R|ADRAR	protein	taxon:9606	20100630	BHF-UCL		UniProtKB:P08913
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P09603	CSF1	enables	GO:0042803	PMID:3264878	IDA		F	Macrophage colony-stimulating factor 1	CSF1	protein	taxon:9606	20090115	BHF-UCL		UniProtKB:P09603
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P10912	GHR	enables	GO:0042803	PMID:1549776	IDA		F	Growth hormone receptor	GHR	protein	taxon:9606	20081205	BHF-UCL		UniProtKB:P10912
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P10912	GHR	enables	GO:0042803	PMID:8137822	IDA		F	Growth hormone receptor	GHR	protein	taxon:9606	20081205	BHF-UCL		UniProtKB:P10912
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P16234	PDGFRA	enables	GO:0042803	PMID:2542288	IDA		F	Platelet-derived growth factor receptor alpha	PDGFRA|PDGFR2|RHEPDGFRA	protein	taxon:9606	20080429	BHF-UCL		UniProtKB:P16234
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P17813	ENG	enables	GO:0042803	PMID:8370410	IPI	UniProtKB:P17813-2	F	Endoglin	ENG|END	protein	taxon:9606	20081109	BHF-UCL		UniProtKB:P17813-2
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P18825	ADRA2C	enables	GO:0042803	PMID:16605244	IDA		F	Alpha-2C adrenergic receptor	ADRA2C|ADRA2L2|ADRA2RL2	protein	taxon:9606	20100630	BHF-UCL		UniProtKB:P18825
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P21333	FLNA	enables	GO:0042803	PMID:2391361	IDA		F	Filamin-A	FLNA|FLN|FLN1	protein	taxon:9606	20080914	BHF-UCL		UniProtKB:P21333
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P22413	ENPP1	enables	GO:0042803	PMID:7830796	IDA		F	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1	ENPP1|M6S1|NPPS|PC1|PDNP1	protein	taxon:9606	20080225	BHF-UCL		UniProtKB:P22413
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P23497	SP100	enables	GO:0042803	PMID:9636146	IPI	UniProtKB:P23497-1	F	Nuclear autoantigen Sp-100	SP100	protein	taxon:9606	20100311	BHF-UCL		UniProtKB:P23497-1
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P23497	SP100	enables	GO:0042803	PMID:9636146	IPI	UniProtKB:P23497-2	F	Nuclear autoantigen Sp-100	SP100	protein	taxon:9606	20081022	BHF-UCL		UniProtKB:P23497-2
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P36894	BMPR1A	enables	GO:0042803	PMID:18436533	IDA		F	Bone morphogenetic protein receptor type-1A	BMPR1A|ACVRLK3|ALK3	protein	taxon:9606	20080613	BHF-UCL		UniProtKB:P36894
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P41235	HNF4A	enables	GO:0042803	PMID:12220494	IDA		F	Hepatocyte nuclear factor 4-alpha	HNF4A|HNF4|NR2A1|TCF14	protein	taxon:9606	20080421	BHF-UCL		UniProtKB:P41235
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P45844	ABCG1	enables	GO:0042803	PMID:16870176	IDA		F	ATP-binding cassette sub-family G member 1	ABCG1|ABC8|WHT1	protein	taxon:9606	20071206	BHF-UCL		UniProtKB:P45844
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P47992	XCL1	enables	GO:0042803	PMID:11889129	IDA		F	Lymphotactin	XCL1|LTN|SCYC1	protein	taxon:9606	20110315	BHF-UCL		UniProtKB:P47992
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P63316	TNNC1	enables	GO:0042803	PMID:18092822	IDA		F	Troponin C, slow skeletal and cardiac muscles	TNNC1|TNNC	protein	taxon:9606	20080512	BHF-UCL		UniProtKB:P63316
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q04771	ACVR1	enables	GO:0042803	PMID:18436533	IDA		F	Activin receptor type-1	ACVR1|ACVRLK2	protein	taxon:9606	20080613	BHF-UCL		UniProtKB:Q04771
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q13253	NOG	enables	GO:0042803	PMID:11562478	IDA		F	Noggin	NOG	protein	taxon:9606	20080711	BHF-UCL		UniProtKB:Q13253
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q13563	PKD2	enables	GO:0042803	PMID:9192675	IDA		F	Polycystin-2	PKD2|TRPP1|TRPP2	protein	taxon:9606	20120112	BHF-UCL		UniProtKB:Q13563
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q16394	EXT1	enables	GO:0042803	PMID:12907669	IDA		F	Exostosin-1	EXT1	protein	taxon:9606	20080228	BHF-UCL		UniProtKB:Q16394
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q6UB35	MTHFD1L	enables	GO:0042803	PMID:16171773	IDA		F	Monofunctional C1-tetrahydrofolate synthase, mitochondrial	MTHFD1L|FTHFSDC1	protein	taxon:9606	20090720	BHF-UCL		UniProtKB:Q6UB35
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q86XE5	HOGA1	enables	GO:0042803	PMID:21998747	IDA		F	4-hydroxy-2-oxoglutarate aldolase, mitochondrial	HOGA1|C10orf65|DHDPSL	protein	taxon:9606	20120710	BHF-UCL		UniProtKB:Q86XE5
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q8IW40	DNAAF19	enables	GO:0042803	PMID:22581229	IDA		F	Dynein axonemal assembly factor 19	DNAAF19|CCDC103	protein	taxon:9606	20120726	BHF-UCL	occurs_in(CL:0002368)	UniProtKB:Q8IW40
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q8WYQ5	DGCR8	enables	GO:0042803	PMID:15574589	IDA		F	Microprocessor complex subunit DGCR8	DGCR8|C22orf12|DGCRK6|LP4941	protein	taxon:9606	20150115	BHF-UCL		UniProtKB:Q8WYQ5
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q92600	CNOT9	enables	GO:0042803	PMID:24768540	IDA		F	CCR4-NOT transcription complex subunit 9	CNOT9|RCD1|RQCD1	protein	taxon:9606	20141222	BHF-UCL		UniProtKB:Q92600
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q92692	NECTIN2	enables	GO:0042803	PMID:9845526	IPI	UniProtKB:Q92692-1	F	Nectin-2	NECTIN2|HVEB|PRR2|PVRL2	protein	taxon:9606	20081128	BHF-UCL		UniProtKB:Q92692-1
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q92692	NECTIN2	enables	GO:0042803	PMID:9845526	IPI	UniProtKB:Q92692-2	F	Nectin-2	NECTIN2|HVEB|PRR2|PVRL2	protein	taxon:9606	20081128	BHF-UCL		UniProtKB:Q92692-2
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q93063	EXT2	NOT|enables	GO:0042803	PMID:12907669	IDA		F	Exostosin-2	EXT2	protein	taxon:9606	20080228	BHF-UCL		UniProtKB:Q93063
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q96BF6	NACC2	enables	GO:0042803	PMID:22926524	IDA		F	Nucleus accumbens-associated protein 2	NACC2|BTBD14A|NAC2|RBB	protein	taxon:9606	20121129	BHF-UCL		UniProtKB:Q96BF6
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q99697	PITX2	enables	GO:0042803	PMID:12612071	IPI	UniProtKB:Q99697-3	F	Pituitary homeobox 2	PITX2|ARP1|RGS|RIEG|RIEG1	protein	taxon:9606	20110922	BHF-UCL		UniProtKB:Q99697-3
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q99697	PITX2	enables	GO:0042803	PMID:19174163	IPI	UniProtKB:Q99697-2	F	Pituitary homeobox 2	PITX2|ARP1|RGS|RIEG|RIEG1	protein	taxon:9606	20111012	BHF-UCL		UniProtKB:Q99697-2
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q9H172	ABCG4	enables	GO:0042803	PMID:16870176	IDA		F	ATP-binding cassette sub-family G member 4	ABCG4|WHITE2	protein	taxon:9606	20071206	BHF-UCL		UniProtKB:Q9H172
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q9H816	DCLRE1B	enables	GO:0042803	PMID:20479256	IDA		F	5' exonuclease Apollo	DCLRE1B|SNM1B	protein	taxon:9606	20161212	BHF-UCL		UniProtKB:Q9H816
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q9NP71	MLXIPL	NOT|enables	GO:0042803	PMID:11230181	IDA		F	Carbohydrate-responsive element-binding protein	MLXIPL|BHLHD14|MIO|WBSCR14	protein	taxon:9606	20080307	BHF-UCL		UniProtKB:Q9NP71
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q9NRR4	DROSHA	enables	GO:0042803	PMID:15574589	IDA		F	Ribonuclease 3	DROSHA|RN3|RNASE3L|RNASEN	protein	taxon:9606	20150115	BHF-UCL		UniProtKB:Q9NRR4
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q9UNQ0	ABCG2	enables	GO:0042803	PMID:16870176	IDA		F	Broad substrate specificity ATP-binding cassette transporter ABCG2	ABCG2|ABCP|BCRP|BCRP1|MXR	protein	taxon:9606	20071206	BHF-UCL		UniProtKB:Q9UNQ0
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q9Y2Z4	YARS2	enables	GO:0042803	PMID:15779907	IPI	UniProtKB:Q6PI48	F	Tyrosine--tRNA ligase, mitochondrial	YARS2|CGI-04	protein	taxon:9606	20110718	BHF-UCL		UniProtKB:Q9Y2Z4
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P15691	VEGFA	enables	GO:0042803	PMID:2798412	IDA		F	Vascular endothelial growth factor A	VEGFA|VEGF	protein	taxon:9913	20080731	BHF-UCL		UniProtKB:P15691
`

###gorule-0000061

Allowed gene product to term relations (gp2term)

* total: 5
#### Messages
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: BFO:0000050 should be one of RO:0001025, RO:0002325, RO:0002432. Repaired to RO:0001025--`UniProtKB	O60716	CTNND1	part_of	GO:0005912	PMID:20123964	IDA		C	Catenin delta-1	CTNND1|KIAA0384	protein	taxon:9606	20241217	BHF-UCL	part_of(CL:0000115)	UniProtKB:O60716
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0001025 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB	P25686	DNAJB2	located_in	GO:0000502	PMID:15936278	IDA		C	DnaJ homolog subfamily B member 2	DNAJB2|HSJ1|HSPF3	protein	taxon:9606	20231121	BHF-UCL		UniProtKB:P25686-2
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: BFO:0000050 should be one of RO:0001025, RO:0002325, RO:0002432. Repaired to RO:0001025--`UniProtKB	P35222	CTNNB1	part_of	GO:0005829	PMID:20123964	IDA		C	Catenin beta-1	CTNNB1|CTNNB|OK/SW-cl.35|PRO2286	protein	taxon:9606	20241217	BHF-UCL	part_of(CL:0000115)	UniProtKB:P35222
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: BFO:0000050 should be one of RO:0001025, RO:0002325, RO:0002432. Repaired to RO:0001025--`UniProtKB	Q15848	ADIPOQ	part_of	GO:0005576	PMID:11222466	IDA		C	Adiponectin	ADIPOQ|ACDC|ACRP30|APM1|GBP28	protein	taxon:9606	20241115	BHF-UCL		UniProtKB:Q15848
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB	Q7KZN9	COX15	is_active_in	GO:0070069	PMID:12474143	IDA		C	Heme A synthase COX15	COX15	protein	taxon:9606	20240209	BHF-UCL		UniProtKB:Q7KZN9
`

###gorule-0000065

Annotations to term that are candidates for obsoletion should be produce a warning

* total: 1
#### Messages
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI	MGI:1316652	Prmt2	involved_in	GO:0032259	PMID:20798359	NAS		P	protein arginine N-methyltransferase 2	Hrmt1l1	protein	NCBITaxon:10090	20110403	BHF-UCL		MGI:MGI:1316652
`