# GORULE violations assigned by CAFA

## SUMMARY

This report generated on 2026-05-21

## Contents

[gorule-0000005](#gorule-0000005)[IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations are not allowed for direct annotations to 'protein binding ; GO:0005515 or GO:0005488 binding'']{}

[gorule-0000020](#gorule-0000020)[Automatic repair of annotations to merged or obsoleted terms]{}

[gorule-0000046](#gorule-0000046)[The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.]{}

[gorule-0000061](#gorule-0000061)[Allowed gene product to term relations (gp2term)]{}

[gorule-0000065](#gorule-0000065)[Annotations to term that are candidates for obsoletion should be produce a warning]{}

## MESSAGES

###gorule-0000005

IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations are not allowed for direct annotations to 'protein binding ; GO:0005515 or GO:0005488 binding''

* total: 4
#### Messages
* WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`MGI	MGI:1891221	Crtap	enables	GO:0005515	GO_REF:0000024	ISS	UniProtKB:Q90830	F	cartilage associated protein	5730529N23Rik|CASP|Leprel3|P3h5	protein	NCBITaxon:10090	20180925	CAFA	has_input(UniProtKB:Q3V1T4),has_input(UniProtKB:P24369)	MGI:MGI:1891221
`
* WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`MGI	MGI:97750	Ppib	enables	GO:0005515	GO_REF:0000024	ISS	UniProtKB:P24367	F	peptidylprolyl isomerase B	Cphn-2|Cphn2|CyP-20b|cyclophilin B	protein	NCBITaxon:10090	20180925	CAFA	has_input(UniProtKB:Q9CYD3),has_input(UniProtKB:Q3V1T4)	MGI:MGI:97750
`
* WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`RGD	620312	Ppib	enables	GO:0005515	GO_REF:0000024	ISS	UniProtKB:P24367	F	peptidylprolyl isomerase B		protein	NCBITaxon:10116	20180925	CAFA		RGD:620312
`
* WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB	P23284	PPIB	enables	GO:0005515	GO_REF:0000024	ISS	UniProtKB:P24367	F	Peptidyl-prolyl cis-trans isomerase B	PPIB|CYPB	protein	taxon:9606	20180925	CAFA	has_input(UniProtKB:O75718),has_input(UniProtKB:Q32P28)	UniProtKB:P23284
`

###gorule-0000020

Automatic repair of annotations to merged or obsoleted terms

* total: 3
#### Messages
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`SGD	S000004490	TSA1	involved_in	GO:0034605	PMID:15163410	IMP		P	thioredoxin peroxidase TSA1	TPX1|YML028W|ZRG14	protein	NCBITaxon:559292	20160526	CAFA	causally_upstream_of(GO:0050821),regulates(GO:0051082)	SGD:S000004490
`
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB	Q04206	RELA	enables	GO:0000977	PMID:18045535	IMP		F	Transcription factor p65	RELA|NFKB3	protein	taxon:9606	20200214	CAFA	has_input(UniProtKB:P23396),part_of(GO:0051092)	UniProtKB:Q04206
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB	Q258K2	MYH9	involved_in	GO:0006903	PMID:18504258	IMP		P	Myosin-9	MYH9	protein	taxon:9615	20161201	CAFA		UniProtKB:Q258K2
`

###gorule-0000046

The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

* total: 61
#### Messages
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:88005	Amelx	enables	GO:0042803	PMID:19086270	IDA		F	amelogenin, X-linked	Amel|Amg|M100888|Rgsc888	protein	NCBITaxon:10090	20161125	CAFA		MGI:MGI:88005
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:98181	Rrm2	enables	GO:0042803	PMID:8876648	IDA		F	ribonucleotide reductase M2	R2	protein	NCBITaxon:10090	20161103	CAFA		MGI:MGI:98181
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`EcoCyc	BIOTINLIG-MONOMER	BirA	enables	GO:0042803	PMID:11124029	IMP		F	DNA-binding transcriptional repressor/biotin-[acetyl-CoA-carboxylase] ligase BirA		protein	NCBITaxon:83333	20161020	CAFA		EcoCyc:BIOTINLIG-MONOMER
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`EcoCyc	E1P-MONOMER	AceE	enables	GO:0042803	PMID:11955070	IDA		F	pyruvate dehydrogenase E1 component		protein	NCBITaxon:83333	20161031	CAFA		EcoCyc:E1P-MONOMER
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`EcoCyc	EG10416-MONOMER	GrpE	enables	GO:0042803	PMID:9103205	IDA		F	nucleotide exchange factor GrpE		protein	NCBITaxon:83333	20160926	CAFA		EcoCyc:EG10416-MONOMER
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`EcoCyc	EG10571-MONOMER	MazE	enables	GO:0042803	PMID:12718874	IDA		F	antitoxin of the MazF-MazE toxin-antitoxin system MazE		protein	NCBITaxon:83333	20161017	CAFA		EcoCyc:EG10571-MONOMER
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`EcoCyc	EG10571-MONOMER	MazE	enables	GO:0042803	PMID:12743116	IDA		F	antitoxin of the MazF-MazE toxin-antitoxin system MazE		protein	NCBITaxon:83333	20161017	CAFA		EcoCyc:EG10571-MONOMER
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`EcoCyc	EG10571-MONOMER	MazE	enables	GO:0042803	PMID:15735309	IDA		F	antitoxin of the MazF-MazE toxin-antitoxin system MazE		protein	NCBITaxon:83333	20161017	CAFA		EcoCyc:EG10571-MONOMER
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`EcoCyc	EG10873-MONOMER	RplL	enables	GO:0042803	PMID:10747797	IDA		F	50S ribosomal subunit protein L12		protein	NCBITaxon:83333	20160630	CAFA		EcoCyc:EG10873-MONOMER
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`EcoCyc	EG10978-MONOMER	SspB	enables	GO:0042803	PMID:14536075	IMP		F	ClpXP protease specificity-enhancing factor		protein	NCBITaxon:83333	20160930	CAFA		EcoCyc:EG10978-MONOMER
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`EcoCyc	EG11249-MONOMER	MazF	enables	GO:0042803	PMID:12718874	IDA		F	endoribonuclease toxin MazF		protein	NCBITaxon:83333	20161017	CAFA		EcoCyc:EG11249-MONOMER
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`EcoCyc	PD00196	Fis	enables	GO:0042803	PMID:11183780	IMP		F	DNA-binding transcriptional dual regulator Fis		protein	NCBITaxon:83333	20161028	CAFA		EcoCyc:PD00196
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`EcoCyc	PD00196	Fis	enables	GO:0042803	PMID:1619650	IDA		F	DNA-binding transcriptional dual regulator Fis		protein	NCBITaxon:83333	20161028	CAFA		EcoCyc:PD00196
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`EcoCyc	PD00196	Fis	enables	GO:0042803	PMID:1946369	IMP		F	DNA-binding transcriptional dual regulator Fis		protein	NCBITaxon:83333	20161028	CAFA		EcoCyc:PD00196
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`EcoCyc	PD00196	Fis	enables	GO:0042803	PMID:9362499	IMP		F	DNA-binding transcriptional dual regulator Fis		protein	NCBITaxon:83333	20161028	CAFA		EcoCyc:PD00196
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`EcoCyc	PDXH-MONOMER	PdxH	enables	GO:0042803	PMID:15858270	IDA		F	pyridoxine/pyridoxamine 5'-phosphate oxidase		protein	NCBITaxon:83333	20160927	CAFA		EcoCyc:PDXH-MONOMER
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`EcoCyc	TAR-MONOMER	Tar	enables	GO:0042803	PMID:15916610	IMP		F	methyl-accepting chemotaxis protein Tar		protein	NCBITaxon:83333	20161017	CAFA		EcoCyc:TAR-MONOMER
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`EcoCyc	TRG-MONOMER	Trg	enables	GO:0042803	PMID:15916610	IMP		F	methyl-accepting chemotaxis protein Trg		protein	NCBITaxon:83333	20161017	CAFA		EcoCyc:TRG-MONOMER
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`RGD	1359514	Scly	enables	GO:0042803	PMID:20164179	IDA		F	selenocysteine lyase		protein	NCBITaxon:10116	20161117	CAFA		RGD:1359514
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`RGD	2553	Eno1	enables	GO:0042803	PMID:7964722	IDA		F	enolase 1		protein	NCBITaxon:10116	20160720	CAFA	occurs_in(GO:0005886)	RGD:2553
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`RGD	2677	Gdnf	enables	GO:0042803	PMID:9187648	IDA		F	glial cell derived neurotrophic factor		protein	NCBITaxon:10116	20160913	CAFA		RGD:2677
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`RGD	2754	Gsta2	enables	GO:0042803	PMID:15152091	IDA		F	glutathione S-transferase alpha 2		protein	NCBITaxon:10116	20161020	CAFA		RGD:2754
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`RGD	3222	Ocm	enables	GO:0042803	PMID:2231727	IDA		F	oncomodulin		protein	NCBITaxon:10116	20161020	CAFA		RGD:3222
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`RGD	3222	Ocm	enables	GO:0042803	PMID:8487302	IDA		F	oncomodulin		protein	NCBITaxon:10116	20161020	CAFA		RGD:3222
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`SGD	S000005299	ACC1	enables	GO:0042803	PMID:15341732	IMP		F	acetyl-CoA carboxylase ACC1	ABP2|FAS3|MTR7|YNR016C	protein	NCBITaxon:559292	20161111	CAFA		SGD:S000005299
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P52477	mexA	involved_in	GO:0051260	PMID:15226509	IMP		P	Multidrug resistance protein MexA	mexA|PA0425	protein	taxon:208964	20161026	CAFA		UniProtKB:P52477
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`FB	FBgn0000024	Ace	enables	GO:0042803	PMID:10892800	IDA		F	Acetylcholine esterase	CG17907	protein	NCBITaxon:7227	20161019	CAFA		FB:FBgn0000024
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`FB	FBgn0000546	EcR	enables	GO:0042803	PMID:22628309	IMP		F	Ecdysone receptor	CG1765	protein	NCBITaxon:7227	20161115	CAFA		FB:FBgn0000546
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`FB	FBgn0011760	ctp	enables	GO:0042803	PMID:15051340	IMP		F	cut up	CG6998	protein	NCBITaxon:7227	20161115	CAFA		FB:FBgn0011760
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`FB	FBgn0011760	ctp	enables	GO:0042803	PMID:15581372	IMP		F	cut up	CG6998	protein	NCBITaxon:7227	20161115	CAFA		FB:FBgn0011760
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`FB	FBgn0011760	ctp	enables	GO:0042803	PMID:19759397	IDA		F	cut up	CG6998	protein	NCBITaxon:7227	20161115	CAFA		FB:FBgn0011760
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`FB	FBgn0024432	Dlc90F	enables	GO:0042803	PMID:19759397	IDA		F	Dynein light chain 90F	CG12363	protein	NCBITaxon:7227	20161115	CAFA		FB:FBgn0024432
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P06733	ENO1	enables	GO:0042803	PMID:3529090	IDA		F	Alpha-enolase	ENO1|ENO1L1|MBPB1|MPB1	protein	taxon:9606	20160718	CAFA		UniProtKB:P06733
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P07602	PSAP	enables	GO:0042803	PMID:18462685	IDA		F	Prosaposin	PSAP|GLBA|SAP1	protein	taxon:9606	20161018	CAFA		UniProtKB:P07602
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P08238	HSP90AB1	enables	GO:0042803	PMID:10811660	IDA		F	Heat shock protein HSP 90-beta	HSP90AB1|HSP90B|HSPC2|HSPC3|HSPCB	protein	taxon:9606	20170110	CAFA		UniProtKB:P08238
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P10912	GHR	enables	GO:0042803	PMID:8943276	IDA		F	Growth hormone receptor	GHR	protein	taxon:9606	20160817	CAFA		UniProtKB:P10912
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P15309	ACP3	enables	GO:0042803	PMID:10639192	IDA		F	Prostatic acid phosphatase	ACP3|ACPP	protein	taxon:9606	20170112	CAFA		UniProtKB:P15309
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P17342	NPR3	enables	GO:0042803	PMID:16870210	IDA		F	Atrial natriuretic peptide receptor 3	NPR3|ANPRC|C5orf23|NPRC	protein	taxon:9606	20161014	CAFA		UniProtKB:P17342
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P19971	TYMP	enables	GO:0042803	PMID:1590793	IDA		F	Thymidine phosphorylase	TYMP|ECGF1	protein	taxon:9606	20160722	CAFA		UniProtKB:P19971
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P23381	WARS1	enables	GO:0042803	PMID:22504299	IDA		F	Tryptophan--tRNA ligase, cytoplasmic	WARS1|IFI53|WARS|WRS	protein	taxon:9606	20170124	CAFA		UniProtKB:P23381
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P24522	GADD45A	enables	GO:0042803	PMID:20460379	IDA		F	Growth arrest and DNA damage-inducible protein GADD45 alpha	GADD45A|DDIT1|GADD45	protein	taxon:9606	20161124	CAFA		UniProtKB:P24522
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P32455	GBP1	enables	GO:0042803	PMID:10676968	IDA		F	Guanylate-binding protein 1	GBP1	protein	taxon:9606	20161215	CAFA		UniProtKB:P32455
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P35638	DDIT3	enables	GO:0042803	PMID:18534616	IDA		F	DNA damage-inducible transcript 3 protein	DDIT3|CHOP|CHOP10|GADD153	protein	taxon:9606	20170113	CAFA		UniProtKB:P35638
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P78356	PIP4K2B	enables	GO:0042803	PMID:9753329	IDA		F	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	PIP4K2B|PIP5K2B	protein	taxon:9606	20160816	CAFA		UniProtKB:P78356
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q04206	RELA	enables	GO:0042803	PMID:18045535	IDA		F	Transcription factor p65	RELA|NFKB3	protein	taxon:9606	20160512	CAFA		UniProtKB:Q04206
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q6PI77	GPRASP3	enables	GO:0042803	GO_REF:0000024	ISS	UniProtKB:Q6PB60	F	G protein-coupled receptor associated sorting protein 3	GPRASP3|BHLHB9|KIAA1701	protein	taxon:9606	20131008	CAFA		UniProtKB:Q6PI77
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q92886	NEUROG1	enables	GO:0042803	PMID:20102160	IDA		F	Neurogenin-1	NEUROG1|BHLHA6|NEUROD3|NGN|NGN1	protein	taxon:9606	20161208	CAFA		UniProtKB:Q92886
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q9H2S9	IKZF4	involved_in	GO:0051260	PMID:15491138	IMP		P	Zinc finger protein Eos	IKZF4|KIAA1782|ZNFN1A4	protein	taxon:9606	20170111	CAFA		UniProtKB:Q9H2S9
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q9NVS9	PNPO	enables	GO:0042803	PMID:12824491	IDA		F	Pyridoxine-5'-phosphate oxidase	PNPO	protein	taxon:9606	20161020	CAFA		UniProtKB:Q9NVS9
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q9Y3M2	CBY1	enables	GO:0042803	PMID:21182262	IDA		F	Protein chibby homolog 1	CBY1|ARB1|C22orf2|CBY|PGEA1|HRIHFB2025	protein	taxon:9606	20161110	CAFA		UniProtKB:Q9Y3M2
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q9Y3M2	CBY1	involved_in	GO:0051289	PMID:21182262	IDA		P	Protein chibby homolog 1	CBY1|ARB1|C22orf2|CBY|PGEA1|HRIHFB2025	protein	taxon:9606	20161110	CAFA		UniProtKB:Q9Y3M2
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P21758	MSR1	involved_in	GO:0070207	PMID:11785981	IMP		P	Macrophage scavenger receptor types I and II	MSR1	protein	taxon:9913	20161011	CAFA		UniProtKB:P21758
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P21793	DCN	enables	GO:0042803	PMID:15501918	IDA		F	Decorin	DCN	protein	taxon:9913	20161104	CAFA		UniProtKB:P21793
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P80457	XDH	enables	GO:0042803	PMID:11005854	IDA		F	Xanthine dehydrogenase/oxidase	XDH	protein	taxon:9913	20161101	CAFA		UniProtKB:P80457
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q28181	CNGB1	enables	GO:0042803	PMID:16280326	IDA		F	Cyclic nucleotide-gated channel beta-1	CNGB1|CNCG4	protein	taxon:9913	20161101	CAFA		UniProtKB:Q28181
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`AGI_LocusCode	AT1G32060	At1g32060	enables	GO:0042803	PMID:16258009	IDA		F	Phosphoribulokinase, chloroplastic	At1g32060|T12O21.4	protein	NCBITaxon:3702	20161110	CAFA		AGI_LocusCode:AT1G32060
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`AGI_LocusCode	AT1G32060	At1g32060	enables	GO:0042803	PMID:17947231	IDA		F	Phosphoribulokinase, chloroplastic	At1g32060|T12O21.4	protein	NCBITaxon:3702	20161110	CAFA		AGI_LocusCode:AT1G32060
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`AGI_LocusCode	AT3G26650	GAPA1	enables	GO:0042803	PMID:22514274	IDA		F	Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic	At3g26650|GAPA|GAPA1|MLJ15.4|MLJ15_5	protein	NCBITaxon:3702	20161110	CAFA		AGI_LocusCode:AT3G26650
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`AGI_LocusCode	AT3G26650	GAPA1	involved_in	GO:0051289	PMID:16258009	IDA		P	Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic	At3g26650|GAPA|GAPA1|MLJ15.4|MLJ15_5	protein	NCBITaxon:3702	20161110	CAFA		AGI_LocusCode:AT3G26650
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`AGI_LocusCode	AT3G26650	GAPA1	involved_in	GO:0051289	PMID:17947231	IDA		P	Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic	At3g26650|GAPA|GAPA1|MLJ15.4|MLJ15_5	protein	NCBITaxon:3702	20161110	CAFA		AGI_LocusCode:AT3G26650
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`AGI_LocusCode	AT3G26650	GAPA1	involved_in	GO:0051289	PMID:22514274	IDA		P	Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic	At3g26650|GAPA|GAPA1|MLJ15.4|MLJ15_5	protein	NCBITaxon:3702	20161110	CAFA		AGI_LocusCode:AT3G26650
`

###gorule-0000061

Allowed gene product to term relations (gp2term)

* total: 1
#### Messages
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002331 should be one of RO:0002326, RO:0002327. Repaired to RO:0002327--`UniProtKB	O00469	PLOD2	involved_in	GO:0008475	PMID:10934207	IDA		F	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2	PLOD2	protein	taxon:9606	20160603	CAFA		UniProtKB:O00469
`

###gorule-0000065

Annotations to term that are candidates for obsoletion should be produce a warning

* total: 1
#### Messages
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q14318	FKBP8	involved_in	GO:0001933	PMID:15733859	IMP		P	Peptidyl-prolyl cis-trans isomerase FKBP8	FKBP8|FKBP38	protein	taxon:9606	20161213	CAFA		UniProtKB:Q14318
`