# GORULE violations assigned by DisProt

## SUMMARY

This report generated on 2026-05-21

## Contents

[gorule-0000006](#gorule-0000006)[IEP and HEP usage is restricted to terms from the Biological Process ontology]{}

[gorule-0000016](#gorule-0000016)[With/From: IC annotations require a With/From GO ID]{}

[gorule-0000020](#gorule-0000020)[Automatic repair of annotations to merged or obsoleted terms]{}

[gorule-0000027](#gorule-0000027)[Each identifier in GAF is valid]{}

[gorule-0000046](#gorule-0000046)[The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.]{}

[gorule-0000061](#gorule-0000061)[Allowed gene product to term relations (gp2term)]{}

[gorule-0000065](#gorule-0000065)[Annotations to term that are candidates for obsoletion should be produce a warning]{}

## MESSAGES

###gorule-0000006

IEP and HEP usage is restricted to terms from the Biological Process ontology

* total: 17
#### Messages
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`MGI	MGI:97769	Prnp	enables	GO:0140677	PMID:28945221	IEP		F	prion protein	CD230|PrP|PrPC|PrPSc|Prn-i|Prn-p|Sinc	protein	NCBITaxon:10090	20220214	DisProt		MGI:MGI:97769
`
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`SGD	S000001880	HSP12	is_active_in	GO:0005829	PMID:20797624	IEP		C	lipid-binding protein HSP12	GLP1|HOR5|YFL014W	protein	NCBITaxon:559292	20251014	DisProt		SGD:S000001880
`
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`SGD	S000001880	HSP12	is_active_in	GO:0016020	PMID:20797624	IEP		C	lipid-binding protein HSP12	GLP1|HOR5|YFL014W	protein	NCBITaxon:559292	20251014	DisProt		SGD:S000001880
`
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`SGD	S000007235	SEM1	enables	GO:0044183	PMID:22343721	IEP		F	proteasome regulatory particle lid subunit SEM1	DSS1|HOD1|YDR363W-A	protein	NCBITaxon:559292	20220214	DisProt		SGD:S000007235
`
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`SGD	S000007235	SEM1	enables	GO:0060090	PMID:24412063	IEP		F	proteasome regulatory particle lid subunit SEM1	DSS1|HOD1|YDR363W-A	protein	NCBITaxon:559292	20220214	DisProt		SGD:S000007235
`
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB	O14672	ADAM10	enables	GO:0042803	PMID:25349418	IEP		F	Disintegrin and metalloproteinase domain-containing protein 10	ADAM10|KUZ|MADM	protein	taxon:9606	20240130	DisProt	has_input(UniProtKB:O14672)	UniProtKB:O14672
`
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB	O75807	PPP1R15A	enables	GO:0019888	PMID:34847777	IEP		F	Protein phosphatase 1 regulatory subunit 15A	PPP1R15A|GADD34	protein	taxon:9606	20241112	DisProt	has_input(UniProtKB:P62136)	UniProtKB:O75807
`
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB	P01106	MYC	enables	GO:0140537	PMID:8755740	IEP		F	Myc proto-oncogene protein	MYC|BHLHE39	protein	taxon:9606	20220610	DisProt		UniProtKB:P01106-1
`
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB	P18564	ITGB6	enables	GO:0140677	PMID:11821050	IEP		F	Integrin beta-6	ITGB6	protein	taxon:9606	20220214	DisProt		UniProtKB:P18564
`
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB	P40337	VHL	enables	GO:0003714	PMID:11641274	IEP		F	von Hippel-Lindau disease tumor suppressor	VHL	protein	taxon:9606	20220214	DisProt		UniProtKB:P40337
`
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB	P46379	BAG6	enables	GO:0140677	PMID:25713138	IEP		F	Large proline-rich protein BAG6	BAG6|BAT3|G3	protein	taxon:9606	20220214	DisProt		UniProtKB:P46379
`
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB	Q06787	FMR1	enables	GO:0008143	PMID:10496225	IEP		F	Fragile X messenger ribonucleoprotein 1	FMR1	protein	taxon:9606	20230119	DisProt		UniProtKB:Q06787
`
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB	Q06787	FMR1	enables	GO:0008266	PMID:10496225	IEP		F	Fragile X messenger ribonucleoprotein 1	FMR1	protein	taxon:9606	20230119	DisProt		UniProtKB:Q06787
`
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB	Q06787	FMR1	enables	GO:0034046	PMID:10496225	IEP		F	Fragile X messenger ribonucleoprotein 1	FMR1	protein	taxon:9606	20230119	DisProt		UniProtKB:Q06787
`
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB	Q16236	NFE2L2	enables	GO:0031625	PMID:16888629	IEP		F	Nuclear factor erythroid 2-related factor 2	NFE2L2|NRF2	protein	taxon:9606	20220808	DisProt	has_input(UniProtKB:Q14145)	UniProtKB:Q16236
`
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB	Q5SWA1	PPP1R15B	enables	GO:0019888	PMID:34847777	IEP		F	Protein phosphatase 1 regulatory subunit 15B	PPP1R15B	protein	taxon:9606	20241112	DisProt	has_input(UniProtKB:P62136)	UniProtKB:Q5SWA1
`
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB	P06836	GAP43	enables	GO:0008289	PMID:1826685	IEP		F	Neuromodulin	GAP43	protein	taxon:9913	20220214	DisProt		UniProtKB:P06836
`

###gorule-0000016

With/From: IC annotations require a With/From GO ID

* total: 1
#### Messages
* WARNING - Violates GO Rule:GORULE:0000016: All IC annotations should include a GO ID in the "With/From" column that is also different from the entry in the "GO ID" column--`PomBase	SPCC584.04	sup35	enables	GO:0000287	PMID:15099522	IC		F	cytoplasmic translation release factor class II, GTPase eRF3	erf3|sup9	protein	NCBITaxon:4896	20231211	DisProt	has_input(ChEBI:18420)	PomBase:SPCC584.04
`

###gorule-0000020

Automatic repair of annotations to merged or obsoleted terms

* total: 1
#### Messages
* ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`RGD	3803	Syt1	involved_in	GO:0048278	PMID:24001110	IMP		P	synaptotagmin 1		protein	NCBITaxon:10116	20240118	DisProt		RGD:3803
`

###gorule-0000027

Each identifier in GAF is valid

* total: 38
#### Messages
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`PomBase	SPBC19C7.10	bqt4	enables	GO:0008289	PMID:38825008	IDA		F	integral nuclear inner membrane protein Bqt4		protein	NCBITaxon:4896	20250617	DisProt	has_input(ChEBI:16337)	PomBase:SPBC19C7.10
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`PomBase	SPBC19C7.10	bqt4	enables	GO:0008289	PMID:38825008	IPI	ChEBI:16337,ChEBI:28494	F	integral nuclear inner membrane protein Bqt4		protein	NCBITaxon:4896	20250617	DisProt		PomBase:SPBC19C7.10
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`UniProtKB	O60568	PLOD3	enables	GO:0036094	PMID:30089812	EXP		F	Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3	PLOD3	protein	taxon:9606	20220214	DisProt	has_input(ChEBI:17659)	UniProtKB:O60568
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`SGD	S000001897	LOC1	enables	GO:0019843	PMID:39558160	IPI	ChEBI:18111	F		YFR001W	protein	NCBITaxon:559292	20250623	DisProt		SGD:S000001897
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`PomBase	SPCC584.04	sup35	enables	GO:0000287	PMID:15099522	IC		F	cytoplasmic translation release factor class II, GTPase eRF3	erf3|sup9	protein	NCBITaxon:4896	20231211	DisProt	has_input(ChEBI:18420)	PomBase:SPCC584.04
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`PomBase	SPBC19C7.10	bqt4	enables	GO:0008289	PMID:38825008	IPI	ChEBI:16337,ChEBI:28494	F	integral nuclear inner membrane protein Bqt4		protein	NCBITaxon:4896	20250617	DisProt		PomBase:SPBC19C7.10
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`SGD	S000006389	ATG13	enables	GO:0008289	PMID:31352862	IMP		F	serine/threonine protein kinase regulatory subunit ATG13	APG13|YPR185W	protein	NCBITaxon:559292	20220525	DisProt	has_input(ChEBI:28874)	SGD:S000006389
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`SGD	S000006389	ATG13	enables	GO:0008289	PMID:31352862	IPI	ChEBI:28874	F	serine/threonine protein kinase regulatory subunit ATG13	APG13|YPR185W	protein	NCBITaxon:559292	20220525	DisProt		SGD:S000006389
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`UniProtKB	O60568	PLOD3	enables	GO:0046872	PMID:30089812	EXP		F	Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3	PLOD3	protein	taxon:9606	20220214	DisProt	has_input(ChEBI:29033),has_input(ChEBI:29035)	UniProtKB:O60568
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`UniProtKB	O60568	PLOD3	enables	GO:0046872	PMID:30089812	EXP		F	Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3	PLOD3	protein	taxon:9606	20220214	DisProt	has_input(ChEBI:29033),has_input(ChEBI:29035)	UniProtKB:O60568
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`AGI_LocusCode	AT5G06760	LEA46	enables	GO:0005507	PMID:29892507	EXP		F	Late embryogenesis abundant protein 46	At5g06760|LEA4-5|LEA46|MPH15.12	protein	NCBITaxon:3702	20240201	DisProt	has_input(ChEBI:29036)	AGI_LocusCode:AT5G06760
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`AGI_LocusCode	AT5G06760	LEA46	enables	GO:0005507	PMID:29892507	IPI	ChEBI:29036	F	Late embryogenesis abundant protein 46	At5g06760|LEA4-5|LEA46|MPH15.12	protein	NCBITaxon:3702	20240201	DisProt		AGI_LocusCode:AT5G06760
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`AGI_LocusCode	AT5G66400	RAB18	enables	GO:0046872	PMID:11049741	IPI	ChEBI:29036,ChEBI:49786	F	Dehydrin Rab18	At5g66400|K1F13.5|RAB18	protein	NCBITaxon:3702	20240409	DisProt		AGI_LocusCode:AT5G66400
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`AGI_LocusCode	AT5G06760	LEA46	enables	GO:0008270	PMID:29892507	IPI	ChEBI:29105	F	Late embryogenesis abundant protein 46	At5g06760|LEA4-5|LEA46|MPH15.12	protein	NCBITaxon:3702	20240201	DisProt		AGI_LocusCode:AT5G06760
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`PomBase	SPAC3G6.02	dss1	enables	GO:0005509	PMID:34439840	EXP		F	proteasome receptor/ubiquitin ligase adaptor Dss1	rpn15|sem1	protein	NCBITaxon:4896	20220214	DisProt	has_input(ChEBI:3312)	PomBase:SPAC3G6.02
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`AGI_LocusCode	AT3G04060	NAC046	enables	GO:0005509	PMID:34439840	EXP		F	NAC domain-containing protein 46	At3g04060|NAC046|T11I18.17	protein	NCBITaxon:3702	20220214	DisProt	has_input(ChEBI:3312)	AGI_LocusCode:AT3G04060
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`SGD	S000001897	LOC1	enables	GO:0140693	PMID:39558160	IDA		F		YFR001W	protein	NCBITaxon:559292	20250623	DisProt	has_input(ChEBI:33697)	SGD:S000001897
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`UniProtKB	A0A1D5PXA5	TRPV4	enables	GO:0008289	PMID:37443299	EXP		F	Transient receptor potential cation channel subfamily V member 4	TRPV4	protein	taxon:9031	20230826	DisProt	has_input(ChEBI:34080)	UniProtKB:A0A1D5PXA5
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`UniProtKB	A0A1D5PXA5	TRPV4	enables	GO:0008289	PMID:37443299	IPI	ChEBI:34080,ChEBI:73001	F	Transient receptor potential cation channel subfamily V member 4	TRPV4	protein	taxon:9031	20230826	DisProt		UniProtKB:A0A1D5PXA5
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`UniProtKB	O15431	SLC31A1	enables	GO:0005507	PMID:36409899	EXP		F	High affinity copper uptake protein 1	SLC31A1|COPT1|CTR1	protein	taxon:9606	20240917	DisProt	has_input(ChEBI:49552)	UniProtKB:O15431
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`AGI_LocusCode	AT5G06760	LEA46	enables	GO:0016151	PMID:29892507	IPI	ChEBI:49786	F	Late embryogenesis abundant protein 46	At5g06760|LEA4-5|LEA46|MPH15.12	protein	NCBITaxon:3702	20240201	DisProt		AGI_LocusCode:AT5G06760
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`AGI_LocusCode	AT5G66400	RAB18	enables	GO:0046872	PMID:11049741	IPI	ChEBI:29036,ChEBI:49786	F	Dehydrin Rab18	At5g66400|K1F13.5|RAB18	protein	NCBITaxon:3702	20240409	DisProt		AGI_LocusCode:AT5G66400
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`MGI	MGI:104727	Cplx1	enables	GO:0008289	PMID:35777466	EXP		F	complexin 1	921-S	protein	NCBITaxon:10090	20230411	DisProt	has_input(ChEBI:78018),has_input(ChEBI:52360)|has_input(ChEBI:60285),has_input(ChEBI:60568)	MGI:MGI:104727
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`AGI_LocusCode	AT3G50970	XERO2	enables	GO:0008289	PMID:27208263	EXP		F	Dehydrin Xero 2	At3g50970|F24M12.10|LTI30|XERO2	protein	NCBITaxon:3702	20251015	DisProt	has_input(ChEBI:60426),has_input(ChEBI:52360)	AGI_LocusCode:AT3G50970
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`AGI_LocusCode	AT3G50970	XERO2	enables	GO:0008289	PMID:27208263	IDA		F	Dehydrin Xero 2	At3g50970|F24M12.10|LTI30|XERO2	protein	NCBITaxon:3702	20251015	DisProt	has_input(ChEBI:60426),has_input(ChEBI:52360)	AGI_LocusCode:AT3G50970
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`MGI	MGI:104727	Cplx1	enables	GO:0008289	PMID:35777466	EXP		F	complexin 1	921-S	protein	NCBITaxon:10090	20230411	DisProt	has_input(ChEBI:78018),has_input(ChEBI:52360)|has_input(ChEBI:60285),has_input(ChEBI:60568)	MGI:MGI:104727
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`AGI_LocusCode	AT3G50970	XERO2	enables	GO:0008289	PMID:27208263	EXP		F	Dehydrin Xero 2	At3g50970|F24M12.10|LTI30|XERO2	protein	NCBITaxon:3702	20251015	DisProt	has_input(ChEBI:60426),has_input(ChEBI:52360)	AGI_LocusCode:AT3G50970
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`AGI_LocusCode	AT3G50970	XERO2	enables	GO:0008289	PMID:27208263	IDA		F	Dehydrin Xero 2	At3g50970|F24M12.10|LTI30|XERO2	protein	NCBITaxon:3702	20251015	DisProt	has_input(ChEBI:60426),has_input(ChEBI:52360)	AGI_LocusCode:AT3G50970
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`MGI	MGI:104727	Cplx1	enables	GO:0008289	PMID:35777466	EXP		F	complexin 1	921-S	protein	NCBITaxon:10090	20230411	DisProt	has_input(ChEBI:78018),has_input(ChEBI:52360)|has_input(ChEBI:60285),has_input(ChEBI:60568)	MGI:MGI:104727
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`SGD	S000001880	HSP12	enables	GO:0008289	PMID:20797624	EXP		F	lipid-binding protein HSP12	GLP1|HOR5|YFL014W	protein	NCBITaxon:559292	20251014	DisProt	has_input(ChEBI:60723)	SGD:S000001880
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`SGD	S000001880	HSP12	enables	GO:0008289	PMID:33485946	IDA		F	lipid-binding protein HSP12	GLP1|HOR5|YFL014W	protein	NCBITaxon:559292	20220308	DisProt	has_input(ChEBI:72999)	SGD:S000001880
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`UniProtKB	A0A1D5PXA5	TRPV4	enables	GO:0008289	PMID:37443299	IPI	ChEBI:34080,ChEBI:73001	F	Transient receptor potential cation channel subfamily V member 4	TRPV4	protein	taxon:9031	20230826	DisProt		UniProtKB:A0A1D5PXA5
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`MGI	MGI:104727	Cplx1	enables	GO:0008289	PMID:35777466	EXP		F	complexin 1	921-S	protein	NCBITaxon:10090	20230411	DisProt	has_input(ChEBI:78018),has_input(ChEBI:52360)|has_input(ChEBI:60285),has_input(ChEBI:60568)	MGI:MGI:104727
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`UniProtKB	O00499	BIN1	enables	GO:0008289	PMID:18658220	EXP		F	Myc box-dependent-interacting protein 1	BIN1|AMPHL	protein	taxon:9606	20240319	DisProt	has_input(ChEBI:78018)	UniProtKB:O00499
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`UniProtKB	P01730	CD4	enables	GO:0008289	PMID:19781520	EXP		F	T-cell surface glycoprotein CD4	CD4	protein	taxon:9606	20220214	DisProt	has_input(ChEBI:78018)	UniProtKB:P01730
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`UniProtKB	P02686	MBP	enables	GO:0008289	PMID:16420483	EXP		F	Myelin basic protein	MBP	protein	taxon:9606	20250321	DisProt	has_input(ChEBI:78018)	UniProtKB:P02686
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`UniProtKB	P02686	MBP	enables	GO:0008289	PMID:16420483	EXP		F	Myelin basic protein	MBP	protein	taxon:9606	20250321	DisProt	has_input(ChEBI:78018)	UniProtKB:P02686-5
`
* WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`UniProtKB	P05455	SSB	enables	GO:0008266	PMID:12842046	IPI	ChEBI:8758	F	Lupus La protein	SSB	protein	taxon:9606	20230711	DisProt		UniProtKB:P05455
`

###gorule-0000046

The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

* total: 8
#### Messages
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:107376	Msi1	enables	GO:0042803	PMID:32225071	IDA		F	musashi RNA-binding protein 1	Msi1|Msi1h|Musahi1|m-Msi-1	protein	NCBITaxon:10090	20240506	DisProt	has_input(UniProtKB:Q61474)	MGI:MGI:107376
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:1925662	Cyren	involved_in	GO:0051260	PMID:30017584	EXP		P	cell cycle regulator of NHEJ	3110062M04Rik	protein	NCBITaxon:10090	20240219	DisProt		MGI:MGI:1925662
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI	MGI:1929258	Kcnip3	enables	GO:0042803	PMID:15746104	EXP		F	Kv channel interacting protein 3, calsenilin	4933407H12Rik|Csen|DREAM|KChIP3|R74849	protein	NCBITaxon:10090	20240313	DisProt	has_input(UniProtKB:Q9QXT8)	MGI:MGI:1929258
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`FB	FBgn0032979	Clamp	enables	GO:0042803	PMID:35409222	EXP		F	Chromatin-linked adaptor for MSL proteins	CG1832	protein	NCBITaxon:7227	20220602	DisProt	has_input(UniProtKB:Q8IGP5)	FB:FBgn0032979
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`FB	FBgn0032979	Clamp	enables	GO:0042803	PMID:35409222	IPI	UniProtKB:Q9V9N4	F	Chromatin-linked adaptor for MSL proteins	CG1832	protein	NCBITaxon:7227	20240513	DisProt		FB:FBgn0032979
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	P80723	BASP1	involved_in	GO:0051260	PMID:32750402	IDA		P	Brain acid soluble protein 1	BASP1|NAP22	protein	taxon:9606	20231127	DisProt		UniProtKB:P80723
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB	Q86VY4	TSPYL5	involved_in	GO:0051260	PMID:40260937	EXP		P	Testis-specific Y-encoded-like protein 5	TSPYL5|KIAA1750	protein	taxon:9606	20250430	DisProt		UniProtKB:Q86VY4
`
* WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`AGI_LocusCode	AT5G06760	LEA46	involved_in	GO:0051260	PMID:29892507	EXP		P	Late embryogenesis abundant protein 46	At5g06760|LEA4-5|LEA46|MPH15.12	protein	NCBITaxon:3702	20240201	DisProt		AGI_LocusCode:AT5G06760
`

###gorule-0000061

Allowed gene product to term relations (gp2term)

* total: 14
#### Messages
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`MGI	MGI:1925662	Cyren	is_active_in	GO:1990391	PMID:30017584	IPI	UniProtKB:P23475|UniProtKB:P70388|UniProtKB:P97313|UniProtKB:Q3KNJ2,UniProtKB:Q8K0Y7|UniProtKB:Q61216|UniProtKB:Q62388|UniProtKB:Q9R207	C	cell cycle regulator of NHEJ	3110062M04Rik	protein	NCBITaxon:10090	20240219	DisProt		MGI:MGI:1925662
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`SGD	S000004802	SGS1	is_active_in	GO:0031422	PMID:24038467	IMP		C	ATP-dependent DNA helicase SGS1	YMR190C	protein	NCBITaxon:559292	20241021	DisProt		SGD:S000004802
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`SGD	S000006389	ATG13	is_active_in	GO:0070772	PMID:27404361	IDA		C	serine/threonine protein kinase regulatory subunit ATG13	APG13|YPR185W	protein	NCBITaxon:559292	20220526	DisProt	has_input(UniProtKB:Q06410),has_input(UniProtKB:Q12142)	SGD:S000006389
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`SGD	S000006389	ATG13	is_active_in	GO:1990316	PMID:27404361	EXP		C	serine/threonine protein kinase regulatory subunit ATG13	APG13|YPR185W	protein	NCBITaxon:559292	20220526	DisProt		SGD:S000006389
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB	O15234	CASC3	is_active_in	GO:0035145	PMID:16931718	EXP		C	Protein CASC3	CASC3|MLN51	protein	taxon:9606	20251124	DisProt		UniProtKB:O15234
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB	O43561	LAT	is_active_in	GO:0036398	PMID:33080222	IDA		C	Linker for activation of T-cells family member 1	LAT	protein	taxon:9606	20231128	DisProt		UniProtKB:O43561-2
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB	O75807	PPP1R15A	is_active_in	GO:0000164	PMID:34847777	IPI	UniProtKB:P62136,UniProtKB:Q9BY44	C	Protein phosphatase 1 regulatory subunit 15A	PPP1R15A|GADD34	protein	taxon:9606	20241112	DisProt		UniProtKB:O75807
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB	P38936	CDKN1A	is_active_in	GO:0070557	PMID:11463845	IPI	UniProtKB:P12004	C	Cyclin-dependent kinase inhibitor 1	CDKN1A|CAP20|CDKN1|CIP1|MDA6|PIC1|SDI1|WAF1	protein	taxon:9606	20240430	DisProt		UniProtKB:P38936
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB	P61244	MAX	is_active_in	GO:0071943	PMID:36174765	EXP		C	Protein max	MAX|BHLHD4	protein	taxon:9606	20250203	DisProt		UniProtKB:P61244
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB	Q16236	NFE2L2	is_active_in	GO:0016592	PMID:32727915	EXP		C	Nuclear factor erythroid 2-related factor 2	NFE2L2|NRF2	protein	taxon:9606	20231122	DisProt		UniProtKB:Q16236
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB	Q5SWA1	PPP1R15B	is_active_in	GO:0000164	PMID:34847777	IPI	UniProtKB:P62136,UniProtKB:Q9BY44	C	Protein phosphatase 1 regulatory subunit 15B	PPP1R15B	protein	taxon:9606	20241112	DisProt		UniProtKB:Q5SWA1
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB	Q5SWA1	PPP1R15B	is_active_in	GO:0000164	PMID:38159565	IPI	UniProtKB:P62136,UniProtKB:Q9BY44	C	Protein phosphatase 1 regulatory subunit 15B	PPP1R15B	protein	taxon:9606	20241112	DisProt		UniProtKB:Q5SWA1
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB	Q92574	TSC1	is_active_in	GO:0033596	PMID:26893383	EXP		C	Hamartin	TSC1|KIAA0243|TSC	protein	taxon:9606	20220616	DisProt		UniProtKB:Q92574
`
* WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB	Q9Y572	RIPK3	is_active_in	GO:0097342	PMID:29681455	EXP		C	Receptor-interacting serine/threonine-protein kinase 3	RIPK3|RIP3	protein	taxon:9606	20241119	DisProt		UniProtKB:Q9Y572
`

###gorule-0000065

Annotations to term that are candidates for obsoletion should be produce a warning

* total: 15
#### Messages
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`EcoCyc	EG10859-MONOMER	Rne	involved_in	GO:0032781	PMID:15236960	IDA		P	ribonuclease E		protein	NCBITaxon:83333	20230223	DisProt		EcoCyc:EG10859-MONOMER
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`EcoCyc	EG10978-MONOMER	SspB	involved_in	GO:0032781	PMID:14536075	EXP		P	ClpXP protease specificity-enhancing factor		protein	NCBITaxon:83333	20230131	DisProt		EcoCyc:EG10978-MONOMER
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`EcoCyc	EG10978-MONOMER	SspB	involved_in	GO:0032781	PMID:14536075	IDA		P	ClpXP protease specificity-enhancing factor		protein	NCBITaxon:83333	20230223	DisProt		EcoCyc:EG10978-MONOMER
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`SGD	S000000453	ARO4	involved_in	GO:0043085	PMID:12540830	IMP		P	3-deoxy-7-phosphoheptulonate synthase ARO4	YBR249C	protein	NCBITaxon:559292	20221008	DisProt		SGD:S000000453
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	O15234	CASC3	involved_in	GO:1902280	PMID:16170325	IDA		P	Protein CASC3	CASC3|MLN51	protein	taxon:9606	20251124	DisProt		UniProtKB:O15234
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P06401	PGR	involved_in	GO:0042326	PMID:20861224	IEP		P	Progesterone receptor	PGR|NR3C3	protein	taxon:9606	20231205	DisProt		UniProtKB:P06401
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P23443	RPS6KB1	involved_in	GO:0043549	PMID:19864428	IDA		P	Ribosomal protein S6 kinase beta-1	RPS6KB1|STK14A	protein	taxon:9606	20250203	DisProt		UniProtKB:P23443
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P38936	CDKN1A	involved_in	GO:0001933	PMID:7958916	IEP		P	Cyclin-dependent kinase inhibitor 1	CDKN1A|CAP20|CDKN1|CIP1|MDA6|PIC1|SDI1|WAF1	protein	taxon:9606	20220214	DisProt		UniProtKB:P38936
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P38936	CDKN1A	involved_in	GO:0001934	PMID:22869755	IEP		P	Cyclin-dependent kinase inhibitor 1	CDKN1A|CAP20|CDKN1|CIP1|MDA6|PIC1|SDI1|WAF1	protein	taxon:9606	20220214	DisProt		UniProtKB:P38936
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P40205	MYCNOS	involved_in	GO:0006469	PMID:24391509	IDA		P	N-cym protein	MYCNOS|CYMN|NCYM	protein	taxon:9606	20240920	DisProt		UniProtKB:P40205
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	P53355	DAPK1	involved_in	GO:0033673	PMID:20103772	IDA		P	Death-associated protein kinase 1	DAPK1|DAPK	protein	taxon:9606	20240829	DisProt		UniProtKB:P53355
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q13546	RIPK1	involved_in	GO:0032147	PMID:22817896	IMP		P	Receptor-interacting serine/threonine-protein kinase 1	RIPK1|RIP|RIP1	protein	taxon:9606	20241120	DisProt		UniProtKB:Q13546
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q8N726	CDKN2A	involved_in	GO:1904666	PMID:10801444	IPI	UniProtKB:Q00987	P	Tumor suppressor ARF	CDKN2A|CDKN2|MLM	protein	taxon:9606	20220726	DisProt		UniProtKB:Q8N726-1
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q8TDX7	NEK7	involved_in	GO:0043549	PMID:12840024	IDA		P	Serine/threonine-protein kinase Nek7	NEK7	protein	taxon:9606	20250625	DisProt		UniProtKB:Q8TDX7
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB	Q9Y572	RIPK3	involved_in	GO:0032147	PMID:22817896	IMP		P	Receptor-interacting serine/threonine-protein kinase 3	RIPK3|RIP3	protein	taxon:9606	20241120	DisProt		UniProtKB:Q9Y572
`