GORULE violations assigned by HGNC-UCL

Contents

gorule-0000008 No annotations should be made to uninformative high level terms

gorule-0000016 With/From: IC annotations require a With/From GO ID

gorule-0000020 Automatic repair of annotations to merged or obsoleted terms

gorule-0000046 The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

gorule-0000061 Allowed gene product to term relations (gp2term)

MESSAGES

gorule-0000008

No annotations should be made to uninformative high level terms

• total: 2

messages

• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:2384968 L2hgdh involved_in GO:0044281 GO_REF:0000024 ISS UniProtKB:Q9H9P8 P L-2-hydroxyglutarate dehydrogenase protein NCBITaxon:10090 20210921 HGNC-UCL MGI:MGI:2384968 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q9H9P8 L2HGDH involved_in GO:0044281 PMID:16005139 IDA P L-2-hydroxyglutarate dehydrogenase, mitochondrial L2HGDH|C14orf160 protein taxon:9606 20210921 HGNC-UCL UniProtKB:Q9H9P8 `

gorule-0000016

With/From: IC annotations require a With/From GO ID

• total: 1

messages

• WARNING - Violates GO Rule:GORULE:0000016: All IC annotations should include a GO ID in the "With/From" column that is also different from the entry in the "GO ID" column--`UniProtKB P60662 MYL6 enables GO:0000146 PMID:16953301 IC GO:0000146 F Myosin light polypeptide 6 MYL6 protein taxon:9823 20070416 HGNC-UCL UniProtKB:P60662 `

gorule-0000020

Automatic repair of annotations to merged or obsoleted terms

• total: 17

messages

• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI MGI:1927550 Ykt6 involved_in GO:0006904 PMID:9211930 ISS UniProtKB:O15498 P YKT6 v-SNARE homolog (S. cerevisiae) 0610042I15Rik|1810013M05Rik protein NCBITaxon:10090 20070906 HGNC-UCL MGI:MGI:1927550 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`RGD 70897 Ykt6 involved_in GO:0006904 PMID:9211930 ISS UniProtKB:O15498 P YKT6 vesicular SNARE protein protein NCBITaxon:10116 20070906 HGNC-UCL RGD:70897 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB O15498 YKT6 involved_in GO:0006904 PMID:9211930 IDA P Synaptobrevin homolog YKT6 YKT6 protein taxon:9606 20060707 HGNC-UCL UniProtKB:O15498 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`WB WBGene00015164 ykt-6 involved_in GO:0006904 PMID:9211930 ISS UniProtKB:O15498 P YKT6 (Yeast v-SNARE) homolog B0361.10|CELE_B0361.10|ykt-6 protein NCBITaxon:6239 20060707 HGNC-UCL WB:WBGene00015164 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q3T000 YKT6 involved_in GO:0006904 GO_REF:0000024 ISS UniProtKB:O15498 P Synaptobrevin homolog YKT6 YKT6 protein taxon:9913 20060707 HGNC-UCL UniProtKB:Q3T000 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`Xenbase XB-GENE-6254082 ykt6.L acts_upstream_of_or_within GO:0006904 GO_REF:0000024 ISS UniProtKB:O15498 P YKT6 v-SNARE homolog L homeolog snare1|xsnare1|ykt6-a|ykt6-b protein taxon:8355 20060707 HGNC-UCL `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`MGI MGI:1927550 Ykt6 involved_in GO:0006903 PMID:9211930 ISS UniProtKB:O15498 P YKT6 v-SNARE homolog (S. cerevisiae) 0610042I15Rik|1810013M05Rik protein NCBITaxon:10090 20070906 HGNC-UCL MGI:MGI:1927550 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`RGD 620970 Tmed10 involved_in GO:0006903 PMID:8663407 NAS P transmembrane p24 trafficking protein 10 protein NCBITaxon:10116 20050905 HGNC-UCL RGD:620970 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`RGD 69243 Tmed2 involved_in GO:0006903 PMID:8663407 NAS P transmembrane p24 trafficking protein 2 protein NCBITaxon:10116 20050905 HGNC-UCL RGD:69243 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`RGD 70897 Ykt6 involved_in GO:0006903 PMID:9211930 ISS UniProtKB:O15498 P YKT6 vesicular SNARE protein protein NCBITaxon:10116 20070906 HGNC-UCL RGD:70897 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB O15498 YKT6 involved_in GO:0006903 PMID:9211930 IDA P Synaptobrevin homolog YKT6 YKT6 protein taxon:9606 20060707 HGNC-UCL UniProtKB:O15498 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`WB WBGene00015164 ykt-6 involved_in GO:0006903 PMID:9211930 ISS UniProtKB:O15498 P YKT6 (Yeast v-SNARE) homolog B0361.10|CELE_B0361.10|ykt-6 protein NCBITaxon:6239 20060707 HGNC-UCL WB:WBGene00015164 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB Q3T000 YKT6 involved_in GO:0006903 GO_REF:0000024 ISS UniProtKB:O15498 P Synaptobrevin homolog YKT6 YKT6 protein taxon:9913 20060707 HGNC-UCL UniProtKB:Q3T000 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`Xenbase XB-GENE-6254082 ykt6.L acts_upstream_of_or_within GO:0006903 GO_REF:0000024 ISS UniProtKB:O15498 P YKT6 v-SNARE homolog L homeolog snare1|xsnare1|ykt6-a|ykt6-b protein taxon:8355 20060707 HGNC-UCL `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`MGI MGI:1915831 Tmed10 involved_in GO:0048199 PMID:17101722 IEP P transmembrane p24 trafficking protein 10 1110014C03Rik|p23|p24delta1 protein NCBITaxon:10090 20070412 HGNC-UCL MGI:MGI:1915831 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`RGD 620970 Tmed10 involved_in GO:0048199 PMID:17101722 IEP P transmembrane p24 trafficking protein 10 protein NCBITaxon:10116 20070412 HGNC-UCL RGD:620970 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB P49755 TMED10 involved_in GO:0048199 GO_REF:0000024 ISS UniProtKB:Q9D1D4 P Transmembrane emp24 domain-containing protein 10 TMED10|TMP21 protein taxon:9606 20070412 HGNC-UCL UniProtKB:P49755 `

gorule-0000046

The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

• total: 16

messages

• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1891731 Stub1 enables GO:0042803 PMID:16307917 IPI UniProtKB:Q9WUD1 F STIP1 homology and U-Box containing protein 1 0610033N24Rik|2210017D18Rik|2310040B03Rik|CHIP protein NCBITaxon:10090 20230221 HGNC-UCL MGI:MGI:1891731 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1926483 Nectin1 enables GO:0042803 PMID:12826663 IPI UniProtKB:Q9JKF6 F nectin cell adhesion molecule 1 Cd111|HIgR|HveC|PRR|PRR1|Pvrl1|nectin-1 protein NCBITaxon:10090 20230221 HGNC-UCL MGI:MGI:1926483 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1930171 Nectin3 enables GO:0042803 PMID:12826663 IPI UniProtKB:Q9JLB9 F nectin cell adhesion molecule 3 2610301B19Rik|3000002N23Rik|4921513D19Rik|Pvrl3|nectin-3 protein NCBITaxon:10090 20230221 HGNC-UCL MGI:MGI:1930171 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:2137858 Cadm3 enables GO:0042803 PMID:12826663 IPI UniProtKB:Q99N28 F cell adhesion molecule 3 BIgR|Igsf4b|Necl-1|Necl1|SynCAM3|Tsll1 protein NCBITaxon:10090 20230221 HGNC-UCL MGI:MGI:2137858 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:97822 Nectin2 enables GO:0042803 PMID:12826663 IPI UniProtKB:P32507 F nectin cell adhesion molecule 2 Cd112|MPH|Pvrl2|Pvs|nectin-2 protein NCBITaxon:10090 20230221 HGNC-UCL MGI:MGI:97822 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P13945 ADRB3 enables GO:0042803 PMID:15123695 IDA F Beta-3 adrenergic receptor ADRB3|ADRB3R|B3AR protein taxon:9606 20060628 HGNC-UCL UniProtKB:P13945 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P20585 MSH3 NOT|enables GO:0042803 PMID:8942985 IDA F DNA mismatch repair protein Msh3 MSH3|DUC1|DUG protein taxon:9606 20060905 HGNC-UCL UniProtKB:P20585 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P21549 AGXT enables GO:0042803 PMID:12899834 IDA F Alanine--glyoxylate aminotransferase AGXT|AGT1|SPAT protein taxon:9606 20060810 HGNC-UCL UniProtKB:P21549 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P43246 MSH2 enables GO:0042803 PMID:8942985 IDA F DNA mismatch repair protein Msh2 MSH2 protein taxon:9606 20060905 HGNC-UCL UniProtKB:P43246 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q07812 BAX enables GO:0042803 PMID:16608847 IDA F Apoptosis regulator BAX BAX|BCL2L4 protein taxon:9606 20070301 HGNC-UCL UniProtKB:Q07812 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q12904 AIMP1 enables GO:0042803 PMID:11306575 IDA F Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 AIMP1|EMAP2|SCYE1 protein taxon:9606 20071018 HGNC-UCL UniProtKB:Q12904 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q15257 PTPA enables GO:0042803 PMID:16916641 IDA F Serine/threonine-protein phosphatase 2A activator PTPA|PPP2R4 protein taxon:9606 20070426 HGNC-UCL UniProtKB:Q15257 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q9NPP4 NLRC4 enables GO:0042803 PMID:15107016 IDA F NLR family CARD domain-containing protein 4 NLRC4|CARD12|CLAN|CLAN1|IPAF|UNQ6189/PRO20215 protein taxon:9606 20060524 HGNC-UCL UniProtKB:Q9NPP4 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q9ULZ3 PYCARD enables GO:0042803 PMID:15030775 IDA F Apoptosis-associated speck-like protein containing a CARD PYCARD|ASC|CARD5|TMS1 protein taxon:9606 20060525 HGNC-UCL UniProtKB:Q9ULZ3 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q9Y2G2 CARD8 enables GO:0042803 PMID:15030775 IDA F Caspase recruitment domain-containing protein 8 CARD8|DACAR|KIAA0955|NDPP1 protein taxon:9606 20060525 HGNC-UCL UniProtKB:Q9Y2G2 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q9Y697 NFS1 enables GO:0042803 PMID:16527810 IDA F Cysteine desulfurase NFS1|NIFS|HUSSY-08 protein taxon:9606 20071022 HGNC-UCL UniProtKB:Q9Y697 `

gorule-0000061

Allowed gene product to term relations (gp2term)

• total: 2

messages

• WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB P12883 MYH7 is_active_in GO:0016459 PMID:12933792 TAS C Myosin-7 MYH7|MYHCB protein taxon:9606 20240214 HGNC-UCL UniProtKB:P12883 `
• WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB P13533 MYH6 is_active_in GO:0016459 PMID:12933792 TAS C Myosin-6 MYH6|MYHCA protein taxon:9606 20240214 HGNC-UCL UniProtKB:P13533 `