# GORULE violations assigned by xenbase

## SUMMARY

This report generated on 2026-05-21

## Contents

[gorule-0000006](#gorule-0000006)[IEP and HEP usage is restricted to terms from the Biological Process ontology]{}

[gorule-0000013](#gorule-0000013)[Taxon-appropriate annotation check]{}

[gorule-0000020](#gorule-0000020)[Automatic repair of annotations to merged or obsoleted terms]{}

[gorule-0000065](#gorule-0000065)[Annotations to term that are candidates for obsoletion should be produce a warning]{}

## MESSAGES

###gorule-0000006

IEP and HEP usage is restricted to terms from the Biological Process ontology

* total: 5
#### Messages
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`Xenbase	XB-GENE-1017281	trim36	is_active_in	GO:0005938	PMID:23615278	IEP		C	tripartite motif containing 36	Haprin	protein	taxon:8364	20220222	Xenbase		
`
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`Xenbase	XB-GENE-1034769	sox9	enables	GO:0003714	PMID:22927467	IEP		F	SRY-box 9	cmd1|cmpd1|sox-9|sox9-a|sox9-b|sra1	protein	taxon:8364	20220222	Xenbase	part_of(GO:0014029)	
`
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`Xenbase	XB-GENE-1034769	sox9	enables	GO:0003714	PMID:22927467	IEP		F	SRY-box 9	cmd1|cmpd1|sox-9|sox9-a|sox9-b|sra1	protein	taxon:8364	20220222	Xenbase	part_of(GO:0048839)	
`
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`Xenbase	XB-GENE-6486303	kmt2d.L	is_active_in	GO:0005737	PMID:31813957	IEP		C	lysine methyltransferase 2D L homeolog	mll2	protein	taxon:8355	20200626	Xenbase		
`
* ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`Xenbase	XB-GENE-866460	aurka.L	located_in	GO:0005813	PMID:39344321	IEP		C	aurora kinase A L homeolog	aik|ark1|aur-a|aura|aurora2|Aurora A|Aurora-A|btak|Eg2|pEg2|stk15|stk6|stk7	protein	taxon:8355	20260410	Xenbase		
`

###gorule-0000013

Taxon-appropriate annotation check

* total: 1
#### Messages
* WARNING - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`Xenbase	XB-GENE-17342057	notch1.L	acts_upstream_of_or_within	GO:1905275	PMID:31899211	IMP		P	notch 1 receptor L homeolog	notch|notch-1|xnotch|x-notch-1|xnotch1|xotch	protein	taxon:8355	20200626	Xenbase		
`

###gorule-0000020

Automatic repair of annotations to merged or obsoleted terms

* total: 2
#### Messages
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`Xenbase	XB-GENE-856300	foxj1.L	acts_upstream_of_or_within_positive_effect	GO:0097711	PMID:24048590	NAS		P	forkhead box J1 L homeolog	foxj1.1|foxj1-a|foxj1-b|hfh-4|hfh4|xfoxj1	protein	taxon:8355	20220509	Xenbase		
`
* WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`Xenbase	XB-GENE-977569	odf2.L	acts_upstream_of_or_within	GO:0097711	PMID:39864486	IMP	Xenbase:XB-MORPHOLINO-29231311|Xenbase:XB-MORPHOLINO-29231312	P	outer dense fiber of sperm tails 2 L homeolog	cenexin	protein	taxon:8355	20260406	Xenbase		
`

###gorule-0000065

Annotations to term that are candidates for obsoletion should be produce a warning

* total: 3
#### Messages
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`Xenbase	XB-GENE-17340943	ccdc88c.L	acts_upstream_of_or_within	GO:0007258	PMID:16026968	IMP		P	coiled-coil domain containing 88C L homeolog	daple|LOC108698716|LOC108699825|XDal	protein	taxon:8355	20181026	Xenbase		
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`Xenbase	XB-GENE-483735	fzd7.L	acts_upstream_of_or_within	GO:0007258	PMID:16026968	IMP		P	frizzled class receptor 7 L homeolog	frizzled 7|frizzled-7|frizzled7|frz-7|frz7|fz7|Fz-7|Xfz7	protein	taxon:8355	20190411	Xenbase		
`
* WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`Xenbase	XB-GENE-6488002	pnhd.L	acts_upstream_of_or_within_negative_effect	GO:0006468	PMID:32859582	IDA		P	pinhead L homeolog	pinhead	protein	taxon:8355	20230711	Xenbase	has_input(Xenbase:XB-GENE-17332607)	
`