# Group: unknown - Dataset: unknown

## SUMMARY

This report generated on 2026-05-21

  * Associations: 864
  * Lines in file (incl headers): 889
  * Lines skipped: 22
## Header From Original Association File

> !gpa-version: 1.2  
> !collation date: 2026-05-20  
> !collated from production models in https://github.com/geneontology/noctua-models/ where col1 matches xenbase; special rules for MGI (https://github.com/geneontology/pipeline/issues/313)  

## Contents

[gorule-0000001](#gorule-0000001)

[gorule-0000002](#gorule-0000002)

[gorule-0000005](#gorule-0000005)

[gorule-0000006](#gorule-0000006)

[gorule-0000007](#gorule-0000007)

[gorule-0000008](#gorule-0000008)

[gorule-0000011](#gorule-0000011)

[gorule-0000013](#gorule-0000013)

[gorule-0000015](#gorule-0000015)

[gorule-0000016](#gorule-0000016)

[gorule-0000017](#gorule-0000017)

[gorule-0000018](#gorule-0000018)

[gorule-0000020](#gorule-0000020)

[gorule-0000022](#gorule-0000022)

[gorule-0000026](#gorule-0000026)

[gorule-0000027](#gorule-0000027)

[gorule-0000029](#gorule-0000029)

[gorule-0000030](#gorule-0000030)

[gorule-0000037](#gorule-0000037)

[gorule-0000039](#gorule-0000039)

[gorule-0000042](#gorule-0000042)

[gorule-0000043](#gorule-0000043)

[gorule-0000046](#gorule-0000046)

[gorule-0000050](#gorule-0000050)

[gorule-0000055](#gorule-0000055)

[gorule-0000058](#gorule-0000058)

[gorule-0000061](#gorule-0000061)

[gorule-0000063](#gorule-0000063)

[gorule-0000064](#gorule-0000064)

[gorule-0000065](#gorule-0000065)

[other](#other)


## MESSAGES

### gorule-0000001

* total: 2
#### Messages
* ERROR - Invalid symbol: Problem parsing references (38499770) -- `Xenbase	XB-GENE-17333137	acts_upstream_of_or_within	GO:0001755	38499770	ECO:0007089			20240402	Xenbase		noctua-model-id=gomodel:6606056e00000416|model-state=production|contributor=https://orcid.org/0000-0001-5495-4588`
* ERROR - Invalid symbol: Problem parsing references (38499770) -- `Xenbase	XB-GENE-17333137	acts_upstream_of_or_within	GO:0016055	38499770	ECO:0007089			20240402	Xenbase		noctua-model-id=gomodel:6606056e00000416|model-state=production|contributor=https://orcid.org/0000-0001-5495-4588`
### gorule-0000002

* total: 0
### gorule-0000005

* total: 1
#### Messages
* WARNING - Violates GO Rule: GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515' -- `Xenbase	XB-GENE-5919104	enables	GO:0005515	PMID:26754771	ECO:0000250	UniProtKB:Q13501		20231023	Xenbase	has_input(Xenbase:XB-GENE-6251797)	noctua-model-id=gomodel:60418ffa00002271|model-state=production|contributor=https://orcid.org/0000-0003-1074-8103
`
### gorule-0000006

* total: 0
### gorule-0000007

* total: 0
### gorule-0000008

* total: 2
#### Messages
* WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- `Xenbase	XB-GENE-919827	acts_upstream_of_or_within	GO:0048856	PMID:32196547	ECO:0000315			20220118	Xenbase	results_in_development_of(XAO:0003029)	model-state=production|noctua-model-id=gomodel:61e0e55600000483|contributor=https://orcid.org/0000-0003-1074-8103
`
* WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- `Xenbase	XB-GENE-487200	enables	GO:0008134	PMID:32894225	ECO:0006051	Xenbase:XB-MORPHOLINO-17249330		20220613	Xenbase	part_of(GO:1904837)	noctua-model-id=gomodel:62900b6400001096|model-state=production|contributor=https://orcid.org/0000-0003-1074-8103
`
### gorule-0000011

* total: 0
### gorule-0000013

* total: 0
### gorule-0000015

* total: 0
### gorule-0000016

* total: 0
### gorule-0000017

* total: 0
### gorule-0000018

* total: 0
### gorule-0000020

* total: 3
#### Messages
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0060725) -- `Xenbase	XB-GENE-17337757	enables	GO:0060725	PMID:20858598	ECO:0006063			20231219	Xenbase		noctua-model-id=gomodel:62b4ffe300003420|model-state=production|contributor=https://orcid.org/0000-0003-1074-8103
`
* ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:1904929) -- `Xenbase	XB-GENE-5846983	enables	GO:1904929	PMID:28427856	ECO:0007752			20230302	Xenbase		model-state=production|contributor=https://orcid.org/0000-0003-1074-8103|noctua-model-id=gomodel:5fadbcf000000317
`
* WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0097711) -- `Xenbase	XB-GENE-977569	acts_upstream_of_or_within	GO:0097711	PMID:39864486	ECO:0006051	Xenbase:XB-MORPHOLINO-29231311|Xenbase:XB-MORPHOLINO-29231312		20260406	Xenbase		noctua-model-id=gomodel:69c59f8a00002601|model-state=production|contributor=https://orcid.org/0000-0001-5495-4588
`
### gorule-0000022

* total: 0
### gorule-0000026

* total: 12
#### Messages
* ERROR - Violates GO Rule: GORULE:0000026: IBA evidence codes should be filtered from main MOD gaf sources -- `Xenbase	XB-GENE-6251681	enables	GO:0001968	GO_REF:0000033	ECO:0000318	UniProtKB:P34901		20201118	Xenbase		model-state=production|contributor=https://orcid.org/0000-0003-1074-8103|noctua-model-id=gomodel:5fadbcf000000317
`
* ERROR - Violates GO Rule: GORULE:0000026: IBA evidence codes should be filtered from main MOD gaf sources -- `Xenbase	XB-GENE-489012	enables	GO:0003924	GO_REF:0000033	ECO:0000318	PANTHER:PTN000632671		20201118	Xenbase		model-state=production|contributor=https://orcid.org/0000-0003-1074-8103|noctua-model-id=gomodel:5fadbcf000000317
`
* ERROR - Violates GO Rule: GORULE:0000026: IBA evidence codes should be filtered from main MOD gaf sources -- `Xenbase	XB-GENE-17331921	enables	GO:0005109	GO_REF:0000033	ECO:0000318	PANTHER:PTN000246517		20201118	Xenbase		model-state=production|contributor=https://orcid.org/0000-0003-1074-8103|noctua-model-id=gomodel:5fadbcf000000317
`
* ERROR - Violates GO Rule: GORULE:0000026: IBA evidence codes should be filtered from main MOD gaf sources -- `Xenbase	XB-GENE-483735	enables	GO:0042813	GO_REF:0000033	ECO:0000318	PANTHER:PTN000139394		20201118	Xenbase		model-state=production|contributor=https://orcid.org/0000-0003-1074-8103|noctua-model-id=gomodel:5fadbcf000000317
`
* ERROR - Violates GO Rule: GORULE:0000026: IBA evidence codes should be filtered from main MOD gaf sources -- `Xenbase	XB-GENE-865024	enables	GO:0005109	GO_REF:0000033	ECO:0000318	PANTHER:PTN000093831		20201118	Xenbase		model-state=production|contributor=https://orcid.org/0000-0003-1074-8103|noctua-model-id=gomodel:5fadbcf000000317
`
* ERROR - Violates GO Rule: GORULE:0000026: IBA evidence codes should be filtered from main MOD gaf sources -- `Xenbase	XB-GENE-17331693	enables	GO:0003723	GO_REF:0000033	ECO:0000318	PANTHER:PTN000259535		20201116	Xenbase		model-state=production|contributor=https://orcid.org/0000-0003-1074-8103|noctua-model-id=gomodel:5fadbcf000000317
`
* ERROR - Violates GO Rule: GORULE:0000026: IBA evidence codes should be filtered from main MOD gaf sources -- `Xenbase	XB-GENE-483735	enables	GO:0017147	GO_REF:0000033	ECO:0000318	PANTHER:PTN000139394		20201118	Xenbase		model-state=production|contributor=https://orcid.org/0000-0003-1074-8103|noctua-model-id=gomodel:5fadbcf000000317
`
* ERROR - Violates GO Rule: GORULE:0000026: IBA evidence codes should be filtered from main MOD gaf sources -- `Xenbase	XB-GENE-852934	enables	GO:0005096	GO_REF:0000033	ECO:0000318	PANTHER:PTN001141948		20201119	Xenbase		model-state=production|contributor=https://orcid.org/0000-0003-1074-8103|noctua-model-id=gomodel:5fadbcf000000317
`
* ERROR - Violates GO Rule: GORULE:0000026: IBA evidence codes should be filtered from main MOD gaf sources -- `Xenbase	XB-GENE-17336014	enables	GO:0072518	GO_REF:0000033	ECO:0000318	PANTHER:PTN000542090		20201119	Xenbase		model-state=production|contributor=https://orcid.org/0000-0003-1074-8103|noctua-model-id=gomodel:5fadbcf000000317
`
* ERROR - Violates GO Rule: GORULE:0000026: IBA evidence codes should be filtered from main MOD gaf sources -- `Xenbase	XB-GENE-1217556	enables	GO:0004705	GO_REF:0000033	ECO:0000318	PANTHER:PTN001171982		20201119	Xenbase		model-state=production|contributor=https://orcid.org/0000-0003-1074-8103|noctua-model-id=gomodel:5fadbcf000000317
`
* ERROR - Violates GO Rule: GORULE:0000026: IBA evidence codes should be filtered from main MOD gaf sources -- `Xenbase	XB-GENE-865070	enables	GO:0042813	GO_REF:0000033	ECO:0000318	PANTHER:PTN000139394		20201116	Xenbase		model-state=production|contributor=https://orcid.org/0000-0003-1074-8103|noctua-model-id=gomodel:5fadbcf000000317
`
* ERROR - Violates GO Rule: GORULE:0000026: IBA evidence codes should be filtered from main MOD gaf sources -- `Xenbase	XB-GENE-865846	enables	GO:0019901	GO_REF:0000033	ECO:0000318	PANTHER:PTN001530052		20201118	Xenbase		model-state=production|contributor=https://orcid.org/0000-0003-1074-8103|noctua-model-id=gomodel:5fadbcf000000317
`
### gorule-0000027

* total: 6
#### Messages
* ERROR - Invalid identifier: GORULE:0000027: contains non letter, non number character, or spaces (XENBASE:XB-gRNA-23659462;XB-gRNA-25874518) -- `Xenbase	XB-GENE-480717	acts_upstream_of_or_within	GO:1904888	PMID:34664392	ECO:0007089	XENBASE:XB-gRNA-23659462;XB-gRNA-25874518		20220106	Xenbase	part_of(GO:0071599)	noctua-model-id=gomodel:61bcf0b700000339|model-state=production|contributor=https://orcid.org/0000-0001-5495-4588
`
* ERROR - Invalid identifier: GORULE:0000027: contains non letter, non number character, or spaces (Xenbase:XB-MORPHOLINO-18375548;) -- `Xenbase	XB-GENE-6254887	involved_in	GO:0021505	PMID:38388461	ECO:0007089	Xenbase:XB-MORPHOLINO-18375548;		20240322	Xenbase	part_of(GO:0001843)	model-state=production|noctua-model-id=gomodel:65f3ae5c00000062|contributor=https://orcid.org/0000-0001-5495-4588
`
* ERROR - Invalid identifier: GORULE:0000027: contains non letter, non number character, or spaces (Xenbase:XB-MORPHOLINO-18375548;) -- `Xenbase	XB-GENE-6254887	enables	GO:0141147	PMID:38388461	ECO:0007089	Xenbase:XB-MORPHOLINO-18375548;		20240322	Xenbase	part_of(GO:0001843),part_of(GO:0021505)	model-state=production|noctua-model-id=gomodel:65f3ae5c00000062|contributor=https://orcid.org/0000-0001-5495-4588
`
* ERROR - Invalid identifier: GORULE:0000027: contains non letter, non number character, or spaces (Xenbase:XB-MORPHOLINO-18375548;) -- `Xenbase	XB-GENE-6254887	involved_in	GO:0001843	PMID:38388461	ECO:0007089	Xenbase:XB-MORPHOLINO-18375548;		20240322	Xenbase		model-state=production|noctua-model-id=gomodel:65f3ae5c00000062|contributor=https://orcid.org/0000-0001-5495-4588
`
* ERROR - Invalid identifier: GORULE:0000027: contains non letter, non number character, or spaces (Xenbase:XB-MORPHOLINO-22249065;Xenbase:XB-MORPHOLINO-29212937) -- `Xenbase	XB-GENE-17333851	acts_upstream_of_or_within	GO:0055010	PMID:38501224	ECO:0007089	Xenbase:XB-MORPHOLINO-22249065;Xenbase:XB-MORPHOLINO-29212937		20240620	Xenbase	part_of(GO:0007507)	model-state=production|noctua-model-id=gomodel:666b894f00001795|contributor=https://orcid.org/0000-0001-5495-4588
`
* ERROR - Invalid identifier: GORULE:0000027: contains non letter, non number character, or spaces (Xenbase:XB-MORPHOLINO-29212947;Xenbase:XB-MORPHOLINO-29212948) -- `Xenbase	XB-GENE-17330203	acts_upstream_of_or_within	GO:0120221	PMID:30665704	ECO:0007089	Xenbase:XB-MORPHOLINO-29212947;Xenbase:XB-MORPHOLINO-29212948		20240627	Xenbase	occurs_in(GO:0005929),occurs_in(XAO:0005179)	model-state=production|noctua-model-id=gomodel:666b894f00002553|contributor=https://orcid.org/0000-0001-5495-4588
`
### gorule-0000029

* total: 0
### gorule-0000030

* total: 0
### gorule-0000037

* total: 0
### gorule-0000039

* total: 0
### gorule-0000042

* total: 0
### gorule-0000043

* total: 0
### gorule-0000046

* total: 0
### gorule-0000050

* total: 0
### gorule-0000055

* total: 0
### gorule-0000058

* total: 0
### gorule-0000061

* total: 5
#### Messages
* WARNING - Violates GO Rule: GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: BFO:0000050 should be one of RO:0002325, RO:0001025, RO:0002432. Repaired to RO:0001025 -- `Xenbase	XB-GENE-5752726	part_of	GO:0031514	PMID:33504787	ECO:0001249			20210210	Xenbase	part_of(XAO:0005179)	noctua-model-id=gomodel:600ced8500001415|model-state=production|contributor=https://orcid.org/0000-0001-5495-4588
`
* WARNING - Violates GO Rule: GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: BFO:0000050 should be one of RO:0002325, RO:0001025, RO:0002432. Repaired to RO:0001025 -- `Xenbase	XB-GENE-5752726	part_of	GO:0036064	PMID:33504787	ECO:0001249			20260313	Xenbase	part_of(GO:0031514),part_of(XAO:0005179)	noctua-model-id=gomodel:600ced8500001415|model-state=production|contributor=https://orcid.org/0000-0003-1074-8103
`
* WARNING - Violates GO Rule: GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0004032 should be one of RO:0002326, RO:0002327. Repaired to RO:0002327 -- `Xenbase	XB-GENE-17337757	acts_upstream_of_or_within_positive_effect	GO:0003700	PMID:20858598	ECO:0006063			20231219	Xenbase		noctua-model-id=gomodel:62b4ffe300003420|model-state=production|contributor=https://orcid.org/0000-0003-1074-8103
`
* WARNING - Violates GO Rule: GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0001025 should be one of BFO:0000050. Repaired to BFO:0000050 -- `Xenbase	XB-GENE-977569	located_in	GO:0120103	PMID:39864486	ECO:0007106			20260406	Xenbase		noctua-model-id=gomodel:69c59f8a00002601|model-state=production|contributor=https://orcid.org/0000-0001-5495-4588
`
* WARNING - Violates GO Rule: GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0001025 should be one of BFO:0000050. Repaired to BFO:0000050 -- `Xenbase	XB-GENE-977569	located_in	GO:0120103	PMID:39864486	ECO:0005601			20260406	Xenbase		noctua-model-id=gomodel:69c59f8a00002601|model-state=production|contributor=https://orcid.org/0000-0001-5495-4588
`
### gorule-0000063

* total: 4
#### Messages
* WARNING - Violates GO Rule: GORULE:0000063: Annotations using ISS/ISA/ISO evidence should refer to a gene product (in the 'with' column) -- `Xenbase	XB-GENE-17339046	enables	GO:0004521	PMID:24683410	ECO:0000266			20200727	Xenbase	part_of(GO:0031016),part_of(GO:0048557),occurs_in(GO:0005737),has_input(Xenbase:XB-GENE-487128)	model-state=production|noctua-model-id=gomodel:5ee8120100002365|contributor=https://orcid.org/0000-0001-5495-4588
`
* WARNING - Violates GO Rule: GORULE:0000063: Annotations using ISS/ISA/ISO evidence should refer to a gene product (in the 'with' column) -- `Xenbase	XB-GENE-996950	acts_upstream_of_or_within	GO:0000380	PMID:33230114	ECO:0000266			20210112	Xenbase	part_of(GO:0001843),occurs_in(GO:0005634),has_input(Xenbase:XB-GENE-6041676)	model-state=production|noctua-model-id=gomodel:5fce9b7300000409|contributor=https://orcid.org/0000-0001-5495-4588
`
* WARNING - Violates GO Rule: GORULE:0000063: Annotations using ISS/ISA/ISO evidence should refer to a gene product (in the 'with' column) -- `Xenbase	XB-GENE-5782073	is_active_in	GO:0000785	PMID:31936777	ECO:0000266			20210909	Xenbase		noctua-model-id=gomodel:61283a3000000756|model-state=production|contributor=https://orcid.org/0000-0001-5495-4588
`
* WARNING - Violates GO Rule: GORULE:0000063: Annotations using ISS/ISA/ISO evidence should refer to a gene product (in the 'with' column) -- `Xenbase	XB-GENE-5782073	enables	GO:0003682	PMID:31936777	ECO:0000266			20210909	Xenbase	occurs_in(GO:0000785)	noctua-model-id=gomodel:61283a3000000756|model-state=production|contributor=https://orcid.org/0000-0001-5495-4588
`
### gorule-0000064

* total: 0
### gorule-0000065

* total: 3
#### Messages
* WARNING - Violates GO Rule: GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed -- `Xenbase	XB-GENE-483735	acts_upstream_of_or_within	GO:0007258	PMID:16026968	ECO:0006063			20190411	Xenbase		noctua-model-id=gomodel:5a7e68a100000628|model-state=production|contributor=https://orcid.org/0000-0003-1074-8103
`
* WARNING - Violates GO Rule: GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed -- `Xenbase	XB-GENE-17340943	acts_upstream_of_or_within	GO:0007258	PMID:16026968	ECO:0006063			20181026	Xenbase		noctua-model-id=gomodel:5a7e68a100000628|model-state=production|contributor=https://orcid.org/0000-0003-1074-8103
`
* WARNING - Violates GO Rule: GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed -- `Xenbase	XB-GENE-6488002	acts_upstream_of_or_within_negative_effect	GO:0006468	PMID:32859582	ECO:0000314			20230711	Xenbase	has_input(Xenbase:XB-GENE-17332607)	model-state=production|contributor=https://orcid.org/0000-0003-1074-8103|noctua-model-id=gomodel:62900b6400002070
`
### other

* total: 0