GORULE violations assigned by ParkinsonsUK-UCL

Contents

gorule-0000008 No annotations should be made to uninformative high level terms

gorule-0000020 Automatic repair of annotations to merged or obsoleted terms

gorule-0000046 The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

MESSAGES

gorule-0000008

No annotations should be made to uninformative high level terms

• total: 40

messages

• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1922022 Atp13a2 involved_in GO:1905123 MGI:MGI:5780535|PMID:24334770 IMP P ATPase type 13A2 1110012E06Rik protein_coding_gene taxon:10090 20160419 ParkinsonsUK-UCL occurs_in(CL:0010012),occurs_in(GO:0005764) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:109531 Cdc37 involved_in GO:0045859 MGI:MGI:5607224|PMID:21855797 IDA P cell division cycle 37 p50Cdc37 protein_coding_gene taxon:10090 20151102 ParkinsonsUK-UCL has_input(UniProtKB:O70405) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:99441 Ckmt1 involved_in GO:0032091 MGI:MGI:5448520|PMID:21370995 IDA P creatine kinase, mitochondrial 1, ubiquitous mi-CK|Mt-CK|UbCKmit protein_coding_gene taxon:10090 20140728 ParkinsonsUK-UCL has_input(UniProtKB:P21796),has_input(UniProtKB:P12236) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1355272 Csnk1d involved_in GO:0006468 MGI:MGI:5705223|PMID:17027228 IGI UniProtKB:Q9JMK2 P casein kinase 1, delta 1200006A05Rik protein_coding_gene taxon:10090 20151221 ParkinsonsUK-UCL has_input(UniProtKB:Q60838),part_of(GO:0030177),occurs_in(CL:0000700) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1351660 Csnk1e involved_in GO:0006468 MGI:MGI:5705223|PMID:17027228 IGI UniProtKB:Q9DC28 P casein kinase 1, epsilon CK1epsilon|CKIepsilon|CKI epsilon|KC1epsilon|tau protein_coding_gene taxon:10090 20151221 ParkinsonsUK-UCL has_input(UniProtKB:Q60838),part_of(GO:0030177),occurs_in(CL:0000700) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:106613 Dvl2 involved_in GO:0043547 MGI:MGI:5466648|PMID:23109420 IDA P dishevelled segment polarity protein 2 protein_coding_gene taxon:10090 20151208 ParkinsonsUK-UCL has_input(UniProtKB:P63001) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:2180139 Edem1 involved_in GO:0036510 MGI:MGI:5645205|PMID:20065073 IMP P ER degradation enhancer, mannosidase alpha-like 1 A130059K23Rik protein_coding_gene taxon:10090 20150623 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1341830 Eif2ak3 involved_in GO:0010998 MGI:MGI:1858648|PMID:10882126 IMP P eukaryotic translation initiation factor 2 alpha kinase 3 PERK protein_coding_gene taxon:10090 20141110 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1341830 Eif2ak3 involved_in GO:0010998 MGI:MGI:5613478|PMID:14676213 IDA P eukaryotic translation initiation factor 2 alpha kinase 3 PERK protein_coding_gene taxon:10090 20141127 ParkinsonsUK-UCL has_input(UniProtKB:Q6ZWX6) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1341830 Eif2ak3 involved_in GO:0018105 MGI:MGI:5613478|PMID:14676213 IDA P eukaryotic translation initiation factor 2 alpha kinase 3 PERK protein_coding_gene taxon:10090 20141127 ParkinsonsUK-UCL has_input(UniProtKB:Q6ZWX6) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1341830 Eif2ak3 involved_in GO:0018105 MGI:MGI:1333015|PMID:9930704 IDA P eukaryotic translation initiation factor 2 alpha kinase 3 PERK protein_coding_gene taxon:10090 20141027 ParkinsonsUK-UCL has_input(UniProtKB:Q6ZWX6),part_of(GO:0017148) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1930134 Ern1 involved_in GO:0043507 MGI:MGI:3777353|PMID:10650002 IMP P endoplasmic reticulum to nucleus signalling 1 9030414B18Rik|Ire1a|Ire1alpha|Ire1p protein_coding_gene taxon:10090 20210421 ParkinsonsUK-UCL part_of(GO:0034976) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1349436 Ern2 involved_in GO:0043507 MGI:MGI:3777353|PMID:10650002 IDA P endoplasmic reticulum to nucleus signalling 2 Ire1b protein_coding_gene taxon:10090 20210421 ParkinsonsUK-UCL part_of(GO:0034976) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1920431 Nfatc4 involved_in GO:0032091 MGI:MGI:5295911|PMID:21880741 IDA P nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4 3110041H08Rik protein_coding_gene taxon:10090 20170410 ParkinsonsUK-UCL has_input(UniProtKB:Q61062),occurs_in(GO:0005634),part_of(GO:0030178)|has_input(UniProtKB:Q02248),occurs_in(GO:0005634),part_of(GO:0030178) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1920431 Nfatc4 involved_in GO:0032091 MGI:MGI:5295911|PMID:21880741 IDA P nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4 3110041H08Rik protein_coding_gene taxon:10090 20151214 ParkinsonsUK-UCL has_input(UniProtKB:P51141),has_input(UniProtKB:Q02248),part_of(GO:0030178) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1917378 Oxsr1 involved_in GO:0018107 MGI:MGI:5574433|PMID:24393035 IGI UniProtKB:Q9Z1W9 P oxidative-stress responsive 1 2210022N24Rik|2810422B09Rik|Osr1 protein_coding_gene taxon:10090 20141006 ParkinsonsUK-UCL has_input(UniProtKB:Q91V14-1)|has_input(UniProtKB:Q924N4-1)|has_input(UniProtKB:Q9WVL3) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1917378 Oxsr1 involved_in GO:1901017 MGI:MGI:5574433|PMID:24393035 IGI UniProtKB:Q9Z1W9 P oxidative-stress responsive 1 2210022N24Rik|2810422B09Rik|Osr1 protein_coding_gene taxon:10090 20141006 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:2135637 Park7 involved_in GO:0051444 MGI:MGI:5575789|PMID:24899725 IC GO:0031397 P Parkinson disease (autosomal recessive, early onset) 7 DJ-1 protein_coding_gene taxon:10090 20140710 ParkinsonsUK-UCL has_input(UniProtKB:P40338) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1916193 Pink1 involved_in GO:0051091 MGI:MGI:5558956|PMID:24553947 IMP P PTEN induced putative kinase 1 1190006F07Rik|brpk protein_coding_gene taxon:10090 20140908 ParkinsonsUK-UCL has_input(UniProtKB:Q61221) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:97805 Ptpn1 acts_upstream_of GO:0043507 MGI:MGI:5616322|PMID:15465829 IMP P protein tyrosine phosphatase, non-receptor type 1 PTP1B|PTP-1B protein_coding_gene taxon:10090 20210421 ParkinsonsUK-UCL part_of(GO:0034976) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:97806 Ptpn2 involved_in GO:0061099 MGI:MGI:5619464|PMID:21216966 IMP P protein tyrosine phosphatase, non-receptor type 2 Ptpt|TC-PTP protein_coding_gene taxon:10090 20150226 ParkinsonsUK-UCL part_of(GO:0034976),has_input(PR:000002997),occurs_in(EMAPA:17503) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:2445001 Rab3gap1 involved_in GO:0043547 MGI:MGI:3652690|PMID:16782817 IMP P RAB3 GTPase activating protein subunit 1 1700003B17Rik|4732493F09Rik|p130 protein_coding_gene taxon:10090 20140731 ParkinsonsUK-UCL occurs_in(EMAPA:16894),has_input(UniProtKB:P63011) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1196458 Scarb2 involved_in GO:1905123 MGI:MGI:5609206|PMID:25316793 IMP P scavenger receptor class B, member 2 9330185J12Rik|Cd36l2|LGP85|LIMP-2|LIMP II protein_coding_gene taxon:10090 20161025 ParkinsonsUK-UCL occurs_in(EMAPA:17563)|occurs_in(EMAPA:16974) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:2135607 Sirt1 involved_in GO:0043433 MGI:MGI:5607229|PMID:20955178 IMP P sirtuin 1 Sir2|Sir2alpha protein_coding_gene taxon:10090 20150121 ParkinsonsUK-UCL has_input(UniProtKB:O35426) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1858416 Stk39 involved_in GO:0018107 MGI:MGI:5574433|PMID:24393035 IGI UniProtKB:Q6P9R2 P serine/threonine kinase 39 DCHT|RF005|Rnl5|SPAK protein_coding_gene taxon:10090 20141006 ParkinsonsUK-UCL has_input(UniProtKB:Q91V14-1)|has_input(UniProtKB:Q924N4-1)|has_input(UniProtKB:Q9WVL3) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1858416 Stk39 involved_in GO:1901017 MGI:MGI:5574433|PMID:24393035 IGI UniProtKB:Q6P9R2 P serine/threonine kinase 39 DCHT|RF005|Rnl5|SPAK protein_coding_gene taxon:10090 20141006 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1891731 Stub1 involved_in GO:0032091 MGI:MGI:5582182|PMID:12150907 IDA P STIP1 homology and U-Box containing protein 1 0610033N24Rik|2210017D18Rik|2310040B03Rik|CHIP protein_coding_gene taxon:10090 20140813 ParkinsonsUK-UCL part_of(GO:0031398) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1891731 Stub1 involved_in GO:0051443 MGI:MGI:5582182|PMID:12150907 IDA P STIP1 homology and U-Box containing protein 1 0610033N24Rik|2210017D18Rik|2310040B03Rik|CHIP protein_coding_gene taxon:10090 20140813 ParkinsonsUK-UCL has_input(UniProtKB:Q9WVS6) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1929658 Tbk1 involved_in GO:0018105 MGI:MGI:5645201|PMID:21617041 IDA P TANK-binding kinase 1 1200008B05Rik protein_coding_gene taxon:10090 20150629 ParkinsonsUK-UCL has_input(UniProtKB:Q8K3K8) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:103306 Tiam1 involved_in GO:0090630 MGI:MGI:5466648|PMID:23109420 IMP P T cell lymphoma invasion and metastasis 1 D16Ium10|D16Ium10e protein_coding_gene taxon:10090 20151208 ParkinsonsUK-UCL has_input(UniProtKB:P63001),occurs_in(CL:0000700),part_of(GO:2000050) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:99682 Tmbim6 involved_in GO:0060702 MGI:MGI:3840374|PMID:19328063 IMP P transmembrane BAX inhibitor motif containing 6 Bax inhibitor 1|Tegt protein_coding_gene taxon:10090 20151008 ParkinsonsUK-UCL has_input(UniProtKB:Q9EQY0) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1914740 Ufl1 involved_in GO:0032092 MGI:MGI:5613470|PMID:21494687 TAS P UFM1 specific ligase 1 1810074P20Rik|Maxer|Rcad protein_coding_gene taxon:10090 20161103 ParkinsonsUK-UCL has_input(UniProtKB:P61961),has_input(UniProtKB:Q80WW9) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1270126 Ulk1 involved_in GO:0018105 MGI:MGI:5607224|PMID:21855797 IDA P unc-51 like kinase 1 Unc51.1 protein_coding_gene taxon:10090 20141201 ParkinsonsUK-UCL has_input(UniProtKB:Q91YI1) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1918722 Usp19 involved_in GO:0071108 MGI:MGI:5614537|PMID:25088257 IDA P ubiquitin specific peptidase 19 8430421I07Rik protein_coding_gene taxon:10090 20150727 ParkinsonsUK-UCL has_input(UniProtKB:Q6ZQ89),part_of(GO:0050821) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:98958 Wnt5a involved_in GO:0032092 MGI:MGI:5466648|PMID:23109420 IDA P wingless-type MMTV integration site family, member 5A 8030457G12Rik|Wnt-5a protein_coding_gene taxon:10090 20170410 ParkinsonsUK-UCL has_input(UniProtKB:Q13009),part_of(GO:0016055),occurs_in(CL:0000700)|has_input(UniProtKB:Q92997),part_of(GO:0016055),occurs_in(CL:0000700) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:98958 Wnt5a involved_in GO:0043547 MGI:MGI:5466648|PMID:23109420 IDA P wingless-type MMTV integration site family, member 5A 8030457G12Rik|Wnt-5a protein_coding_gene taxon:10090 20151208 ParkinsonsUK-UCL has_input(UniProtKB:P63001),occurs_in(CL:0000700) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:98958 Wnt5a involved_in GO:0090630 MGI:MGI:3829860|PMID:18953410 IDA P wingless-type MMTV integration site family, member 5A 8030457G12Rik|Wnt-5a protein_coding_gene taxon:10090 20151126 ParkinsonsUK-UCL has_input(UniProtKB:P63001),part_of(GO:0071542) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB H3BPP0 CHRFAM7A involved_in GO:1903049 PMID:21718690 IDA P Neurotransmitter-gated ion-channel ligand-binding domain-containing protein CHRFAM7A protein taxon:9606 20140609 ParkinsonsUK-UCL has_input(UniProtKB:P36544) UniProtKB:H3BPP0 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB O75928 PIAS2 involved_in GO:0043433 PMID:20408817 IDA P E3 SUMO-protein ligase PIAS2 PIAS2|PIASX protein taxon:9606 20160202 ParkinsonsUK-UCL has_input(UniProtKB:P17861-2) UniProtKB:O75928-1 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q8N726 CDKN2A involved_in GO:0000422 PMID:25217637 IMP P Tumor suppressor ARF CDKN2A|CDKN2|MLM protein taxon:9606 20150310 ParkinsonsUK-UCL has_input(UniProtKB:O60260),has_input(UniProtKB:Q9BXM7),occurs_in(CL:0002608) UniProtKB:Q8N726-2 `

gorule-0000020

Automatic repair of annotations to merged or obsoleted terms

• total: 3

messages

• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI MGI:1355296 Prkn involved_in GO:0032436 MGI:MGI:5543313|PMID:23858059 IMP P parkin RBR E3 ubiquitin protein ligase Park2|Parkin|PRKN protein_coding_gene taxon:10090 20140729 ParkinsonsUK-UCL has_input(UniProtKB:Q8VBV4),part_of(GO:1903204),occurs_in(CL:0000530),occurs_in(EMAPA:16894) `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI MGI:98953 Wnt1 involved_in GO:0036520 MGI:MGI:5770063|PMID:21752258 IMP P wingless-type MMTV integration site family, member 1 Int-1|Wnt-1 protein_coding_gene taxon:10090 20190918 ParkinsonsUK-UCL occurs_in(EMAPA:16974),causally_upstream_of(GO:1903204) `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI MGI:98953 Wnt1 enables GO:0048018 MGI:MGI:5770063|PMID:21752258 IC GO:1903204 F wingless-type MMTV integration site family, member 1 Int-1|Wnt-1 protein_coding_gene taxon:10090 20160914 ParkinsonsUK-UCL has_input(UniProtKB:O70421),part_of(GO:0060070) `

gorule-0000046

The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

• total: 4

messages

• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1921256 Dnm1l enables GO:0042803 MGI:MGI:4459561|PMID:20585624 IPI UniProtKB:Q8K1M6 F dynamin 1-like 6330417M19Rik|Dnmlp1|Drp1|python protein_coding_gene taxon:10090 20230309 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1352504 Hip1r enables GO:0042803 MGI:MGI:5805370|PMID:11564758 IPI UniProtKB:Q9JKY5 F huntingtin interacting protein 1 related protein_coding_gene taxon:10090 20230309 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1352504 Hip1r enables GO:0042803 MGI:MGI:5805365|PMID:18790740 IPI UniProtKB:Q9JKY5 F huntingtin interacting protein 1 related protein_coding_gene taxon:10090 20230309 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1352504 Hip1r enables GO:0042803 MGI:MGI:5763378|PMID:15533940 IPI UniProtKB:Q9JKY5 F huntingtin interacting protein 1 related protein_coding_gene taxon:10090 20230309 ParkinsonsUK-UCL `