Table of contents

Summary

GAF summary

Found 122418 annotations in 122437 lines.

GAF Validation Summary Errors are reported first.

For rule GO_AR:0000005 (http://www.geneontology.org/GO.annotation_qc.shtml#GO_AR:0000005) No ISS or ISS-related annotations to 'protein binding ; GO:0005515', there are 7 violations with type Error.

For rule GO_AR:0000014 (http://www.geneontology.org/GO.annotation_qc.shtml#GO_AR:0000014) Valid GO term ID, there are 13 violations with type Error.

For rule GO_AR:0000003 (http://www.geneontology.org/GO.annotation_qc.shtml#GO_AR:0000003) Annotations to 'binding ; GO:0005488' and 'protein binding ; GO:0005515' should be made with IPI and an interactor in the 'with' field, there are 8 violations with type Warning.

For rule GO_AR:0000008 (http://www.geneontology.org/GO.annotation_qc.shtml#GO_AR:0000008) No annotations should be made to uninformative high level terms, there are 2 violations with type Warning.

GAF Prediction Summary

Found 140 predictions, see prediction file for details.

Used Ontology Summary

go/extensions/go-gaf    go/releases/2019-08-16/extensions/go-gaf.owl

Report

Group: goa - Dataset: goa_cow

SUMMARY

This report generated on 2019-08-20

Header From Original Association File

!gaf-version: 2.1
!
!The set of protein accessions included in this file is based on UniProt reference proteomes, which provide one protein per gene.
!They include the protein sequences annotated in Swiss-Prot or the longest TrEMBL transcript if there is no Swiss-Prot record.
!If a particular protein accession is not annotated with GO, then it will not appear in this file.
!
!Note that the annotation set in this file is filtered in order to reduce redundancy; the full, unfiltered set can be found in
!ftp://ftp.ebi.ac.uk/pub/databases/GO/goa/UNIPROT/goa_uniprot_all.gz
!
!Generated: 2019-07-29 13:51
!GO-version: http://purl.obolibrary.org/obo/go/releases/2019-07-17/extensions/go-plus.owl
!

Contents

gorule-0000008

gorule-0000033

other

MESSAGES

gorule-0000008

No annotations should be made to uninformative high level terms

Messages

gorule-0000033

Public Reference IDs (PMID, PMC, doi, or GO_REF) should be preferred over group specific Reference IDs

Messages

other

OWLTools check

#Line number RuleID ViolationType Message Line
#------------
#------------
# Validation for #122418 annotations in 122437 lines
#------------
#Line number RuleID ViolationType Message Line
#------------
# GO_AR:0000005 No ISS or ISS-related annotations to 'protein binding ; GO:0005515' Error count: 7
38589 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB E1BJ75 CRTAP GO:0005515 GO_REF:0000024 ISS UniProtKB:Q90830 F Cartilage associated protein CRTAP protein taxon:9913 20180925 UniProt
81225 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB P08169 IGF2R GO:0005515 GO_REF:0000024 ISS UniProtKB:P11717 F Cation-independent mannose-6-phosphate receptor IGF2R|M6P protein taxon:9913 20091210 UniProt
82842 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB P18341 TGFB1 GO:0005515 GO_REF:0000024 ISS UniProtKB:P01137 F Transforming growth factor beta-1 proprotein TGFB1 protein taxon:9913 20141202 AgBase
88795 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB P80012 VWF GO:0005515 GO_REF:0000024 ISS UniProtKB:P04275 F von Willebrand factor VWF|F8VWF protein taxon:9913 20070328 UniProt
88901 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB P80311 PPIB GO:0005515 GO_REF:0000024 ISS UniProtKB:P24367 F Peptidyl-prolyl cis-trans isomerase B PPIB protein taxon:9913 20180925 UniProt
108435 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB Q3MHX6 OS9 GO:0005515 GO_REF:0000024 ISS UniProtKB:Q13438 F Protein OS-9 OS9 protein taxon:9913 20090907 UniProt
108895 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB Q3SX24 FBXO6 GO:0005515 GO_REF:0000024 ISS UniProtKB:Q9QZN4 F F-box only protein 6 FBXO6|FBS2|FBX6 protein taxon:9913 20090903 UniProt
#------------
# GO_AR:0000014 Valid GO term ID Error count: 13
79647 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0010867 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911)
79647 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0010867 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911)
79657 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045542 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911)
79657 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045542 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911)
79659 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045723 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001911),has_agent(UBERON:0002107),occurs_in(UBERON:0001013)
79659 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045723 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001911),has_agent(UBERON:0002107),occurs_in(UBERON:0001013)
79660 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045723 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911)
79660 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045723 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911)
79665 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0071073 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001911),has_agent(UBERON:0002107),occurs_in(UBERON:0001013)
79665 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0071073 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001911),has_agent(UBERON:0002107),occurs_in(UBERON:0001013)
79666 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:1900482 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911)
79666 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:1900482 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911)
97191 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB Q17R14 MYO1D GO:0061502 GO_REF:0000024 ISS UniProtKB:F1PRN2 P Unconventional myosin-Id MYO1D protein taxon:9913 20140311 UniProt has_agent(GO:0005884)
#------------
# GO_AR:0000003 Annotations to 'binding ; GO:0005488' and 'protein binding ; GO:0005515' should be made with IPI and an interactor in the 'with' field Warning count: 8
38589 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB E1BJ75 CRTAP GO:0005515 GO_REF:0000024 ISS UniProtKB:Q90830 F Cartilage associated protein CRTAP protein taxon:9913 20180925 UniProt
80418 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB P04272 ANXA2 GO:0005515 PMID:18597635 TAS F Annexin A2 ANXA2|ANX2 protein taxon:9913 20140514 AgBase
81225 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB P08169 IGF2R GO:0005515 GO_REF:0000024 ISS UniProtKB:P11717 F Cation-independent mannose-6-phosphate receptor IGF2R|M6P protein taxon:9913 20091210 UniProt
82842 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB P18341 TGFB1 GO:0005515 GO_REF:0000024 ISS UniProtKB:P01137 F Transforming growth factor beta-1 proprotein TGFB1 protein taxon:9913 20141202 AgBase
88795 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB P80012 VWF GO:0005515 GO_REF:0000024 ISS UniProtKB:P04275 F von Willebrand factor VWF|F8VWF protein taxon:9913 20070328 UniProt
88901 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB P80311 PPIB GO:0005515 GO_REF:0000024 ISS UniProtKB:P24367 F Peptidyl-prolyl cis-trans isomerase B PPIB protein taxon:9913 20180925 UniProt
108435 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB Q3MHX6 OS9 GO:0005515 GO_REF:0000024 ISS UniProtKB:Q13438 F Protein OS-9 OS9 protein taxon:9913 20090907 UniProt
108895 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB Q3SX24 FBXO6 GO:0005515 GO_REF:0000024 ISS UniProtKB:Q9QZN4 F F-box only protein 6 FBXO6|FBS2|FBX6 protein taxon:9913 20090903 UniProt
#------------
# GO_AR:0000008 No annotations should be made to uninformative high level terms Warning count: 2
89023 GO_AR:0000008 Warning Do not annotate to: GO:0005622 'intracellular' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB P81287 ANXA5 GO:0005622 GO_REF:0000024 ISS UniProtKB:P08758 C Annexin A5 ANXA5|ANX5 protein taxon:9913 20061003 AgBase
101300 GO_AR:0000008 Warning Do not annotate to: GO:0005622 'intracellular' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB Q2HJ92 PRKRA GO:0005622 GO_REF:0000024 ISS UniProtKB:Q9WTX2 C Interferon-inducible double-stranded RNA-dependent protein kinase activator A PRKRA protein taxon:9913 20070616 AgBase
#------------

Predictions

GO:0005623 cell AnnotationPropagation C GO:0090110 COPII-coated vesicle cargo loading ISS
GO:0016020 membrane AnnotationPropagation C GO:0090110 COPII-coated vesicle cargo loading ISS
GO:0005623 cell AnnotationPropagation C GO:1990126 retrograde transport, endosome to plasma membrane ISS
GO:0005623 cell AnnotationPropagation C GO:0035751 regulation of lysosomal lumen pH ISS
GO:0098734 macromolecule depalmitoylation AnnotationPropagation P GO:0008474 palmitoyl-(protein) hydrolase activity ISS
GO:0005623 cell AnnotationPropagation C GO:0035356 cellular triglyceride homeostasis ISS
GO:0006897 endocytosis AnnotationPropagation P GO:0070287 ferritin receptor activity ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:1990180 mitochondrial tRNA 3'-end processing ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0070901 mitochondrial tRNA methylation ISS
GO:0005623 cell AnnotationPropagation C GO:1903445 protein transport from ciliary membrane to plasma membrane ISS
GO:0016020 membrane AnnotationPropagation C GO:1903445 protein transport from ciliary membrane to plasma membrane ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0070126 mitochondrial translational termination ISS
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0070915 lysophosphatidic acid receptor activity ISS
GO:0005623 cell AnnotationPropagation C GO:0090110 COPII-coated vesicle cargo loading ISS
GO:0016020 membrane AnnotationPropagation C GO:0090110 COPII-coated vesicle cargo loading ISS
GO:0005623 cell AnnotationPropagation C GO:0061015 snRNA import into nucleus ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0070330 aromatase activity ISS
GO:0016310 phosphorylation AnnotationPropagation P GO:0008887 glycerate kinase activity ISS
GO:0007268 chemical synaptic transmission AnnotationPropagation P GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential IMP
GO:0034220 ion transmembrane transport AnnotationPropagation P GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential IMP
GO:0060078 regulation of postsynaptic membrane potential AnnotationPropagation P GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential IMP
GO:0005623 cell AnnotationPropagation C GO:1990126 retrograde transport, endosome to plasma membrane ISS
GO:0005623 cell AnnotationPropagation C GO:0090110 COPII-coated vesicle cargo loading ISS
GO:0016020 membrane AnnotationPropagation C GO:0090110 COPII-coated vesicle cargo loading ISS
GO:0005623 cell AnnotationPropagation C GO:0051310 metaphase plate congression ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0030974 thiamine pyrophosphate transmembrane transport AnnotationPropagation P GO:0090422 thiamine pyrophosphate transmembrane transporter activity ISS
GO:0035461 vitamin transmembrane transport AnnotationPropagation P GO:0090422 thiamine pyrophosphate transmembrane transporter activity ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0033617 mitochondrial respiratory chain complex IV assembly ISS
GO:0035513 oxidative RNA demethylation AnnotationPropagation P GO:1990931 RNA N6-methyladenosine dioxygenase activity ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0007268 chemical synaptic transmission AnnotationPropagation P GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential IMP
GO:0034220 ion transmembrane transport AnnotationPropagation P GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential IMP
GO:0060078 regulation of postsynaptic membrane potential AnnotationPropagation P GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential IMP
GO:0005623 cell AnnotationPropagation C GO:0006878 cellular copper ion homeostasis ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005623 cell AnnotationPropagation C GO:0051480 regulation of cytosolic calcium ion concentration ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0098821 BMP receptor activity ISS
GO:0030509 BMP signaling pathway AnnotationPropagation P GO:0098821 BMP receptor activity ISS
GO:0005623 cell AnnotationPropagation C GO:0045046 protein import into peroxisome membrane ISS
GO:0016310 phosphorylation AnnotationPropagation P GO:0051731 polynucleotide 5'-hydroxyl-kinase activity ISS
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic AnnotationPropagation P GO:0090624 endoribonuclease activity, cleaving miRNA-paired mRNA ISS
GO:0035279 mRNA cleavage involved in gene silencing by miRNA AnnotationPropagation P GO:0090624 endoribonuclease activity, cleaving miRNA-paired mRNA ISS
GO:0005623 cell AnnotationPropagation C GO:0051452 intracellular pH reduction ISS
GO:0006508 proteolysis AnnotationPropagation P GO:0070573 metallodipeptidase activity ISS
GO:0005764 lysosome AnnotationPropagation C GO:1905146 lysosomal protein catabolic process ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0033617 mitochondrial respiratory chain complex IV assembly ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0090615 mitochondrial mRNA processing ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process ISS
GO:0007165 signal transduction AnnotationPropagation P GO:0005179 hormone activity IMP
GO:0070933 histone H4 deacetylation AnnotationPropagation P GO:0097372 NAD-dependent histone deacetylase activity (H3-K18 specific) ISS
GO:0036065 fucosylation AnnotationPropagation P GO:0046920 alpha-(1->3)-fucosyltransferase activity ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0033617 mitochondrial respiratory chain complex IV assembly ISS
GO:0051726 regulation of cell cycle AnnotationPropagation P GO:0097472 cyclin-dependent protein kinase activity ISS
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0097472 cyclin-dependent protein kinase activity ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0070124 mitochondrial translational initiation IDA
GO:0035513 oxidative RNA demethylation AnnotationPropagation P GO:1990930 RNA N1-methyladenosine dioxygenase activity ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0006479 protein methylation AnnotationPropagation P GO:0071885 N-terminal protein N-methyltransferase activity ISS
GO:0006412 translation AnnotationPropagation P GO:0008079 translation termination factor activity ISS
GO:0006415 translational termination AnnotationPropagation P GO:0008079 translation termination factor activity ISS
GO:0006417 regulation of translation AnnotationPropagation P GO:0008079 translation termination factor activity ISS
GO:0005623 cell AnnotationPropagation C GO:0042073 intraciliary transport ISS
GO:0005929 cilium AnnotationPropagation C GO:0042073 intraciliary transport ISS
GO:0016567 protein ubiquitination AnnotationPropagation P GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination ISS
GO:0006470 protein dephosphorylation AnnotationPropagation P GO:0101006 protein histidine phosphatase activity IDA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0140359 ABC-type transmembrane transporter activity ISS
GO:0006508 proteolysis AnnotationPropagation P GO:0036459 thiol-dependent ubiquitinyl hydrolase activity ISS
GO:0005623 cell AnnotationPropagation C GO:0051168 nuclear export ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0042407 cristae formation ISS
GO:0005623 cell AnnotationPropagation C GO:1903445 protein transport from ciliary membrane to plasma membrane ISS
GO:0016020 membrane AnnotationPropagation C GO:1903445 protein transport from ciliary membrane to plasma membrane ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005739 mitochondrion AnnotationPropagation C GO:0070145 mitochondrial asparaginyl-tRNA aminoacylation ISS
GO:0035435 phosphate ion transmembrane transport AnnotationPropagation P GO:0061513 glucose 6-phosphate:inorganic phosphate antiporter activity ISS
GO:0015712 hexose phosphate transport AnnotationPropagation P GO:0061513 glucose 6-phosphate:inorganic phosphate antiporter activity ISS
GO:0015711 organic anion transport AnnotationPropagation P GO:0061513 glucose 6-phosphate:inorganic phosphate antiporter activity ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0097345 mitochondrial outer membrane permeabilization ISS
GO:0005623 cell AnnotationPropagation C GO:1990126 retrograde transport, endosome to plasma membrane ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005623 cell AnnotationPropagation C GO:1990036 calcium ion import into sarcoplasmic reticulum ISS
GO:0005737 cytoplasm AnnotationPropagation C GO:1990036 calcium ion import into sarcoplasmic reticulum ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0034553 mitochondrial respiratory chain complex II assembly ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0043085 positive regulation of catalytic activity AnnotationPropagation P GO:0060230 lipoprotein lipase activator activity NAS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005739 mitochondrion AnnotationPropagation C GO:0070124 mitochondrial translational initiation ISS
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0102758 very-long-chain enoyl-CoA reductase activity ISS
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0015054 gastrin receptor activity ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0016311 dephosphorylation AnnotationPropagation P GO:0052834 inositol monophosphate phosphatase activity IDA
GO:0005739 mitochondrion AnnotationPropagation C GO:0097345 mitochondrial outer membrane permeabilization ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0033617 mitochondrial respiratory chain complex IV assembly ISS
GO:0032259 methylation AnnotationPropagation P GO:0046539 histamine N-methyltransferase activity ISS
GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity ISS
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0050254 rhodopsin kinase activity ISS
GO:0006508 proteolysis AnnotationPropagation P GO:0070006 metalloaminopeptidase activity ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0010452 histone H3-K36 methylation AnnotationPropagation P GO:0046975 histone methyltransferase activity (H3-K36 specific) ISS
GO:0005623 cell AnnotationPropagation C GO:0006626 protein targeting to mitochondrion ISS
GO:0016311 dephosphorylation AnnotationPropagation P GO:0098519 nucleotide phosphatase activity, acting on free nucleotides ISS
GO:0005623 cell AnnotationPropagation C GO:1990126 retrograde transport, endosome to plasma membrane ISS
GO:0005623 cell AnnotationPropagation C GO:0071333 cellular response to glucose stimulus ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005739 mitochondrion AnnotationPropagation C GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death ISS
GO:0005623 cell AnnotationPropagation C GO:1990126 retrograde transport, endosome to plasma membrane ISS
GO:0016311 dephosphorylation AnnotationPropagation P GO:0043874 acireductone synthase activity ISS
GO:0005623 cell AnnotationPropagation C GO:0051168 nuclear export ISS
GO:0005623 cell AnnotationPropagation C GO:0051281 positive regulation of release of sequestered calcium ion into cytosol ISS
GO:0016311 dephosphorylation AnnotationPropagation P GO:0098519 nucleotide phosphatase activity, acting on free nucleotides ISS
GO:0006412 translation AnnotationPropagation P GO:0008135 translation factor activity, RNA binding ISS
GO:0006417 regulation of translation AnnotationPropagation P GO:0008135 translation factor activity, RNA binding ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0010950 positive regulation of endopeptidase activity AnnotationPropagation P GO:0061133 endopeptidase activator activity ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly ISS
GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine AnnotationPropagation P GO:0035243 protein-arginine omega-N symmetric methyltransferase activity ISS
GO:0016310 phosphorylation AnnotationPropagation P GO:0051736 ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0097345 mitochondrial outer membrane permeabilization ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0006508 proteolysis AnnotationPropagation P GO:0070006 metalloaminopeptidase activity ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation HDA
GO:0005623 cell AnnotationPropagation C GO:0051560 mitochondrial calcium ion homeostasis ISS
GO:0005739 mitochondrion AnnotationPropagation C GO:0051560 mitochondrial calcium ion homeostasis ISS
GO:0043985 histone H4-R3 methylation AnnotationPropagation P GO:0044020 histone methyltransferase activity (H4-R3 specific) ISS
GO:0035246 peptidyl-arginine N-methylation AnnotationPropagation P GO:0044020 histone methyltransferase activity (H4-R3 specific) ISS
GO:0031594 neuromuscular junction FoldBasedPredictor GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential occurs_in GO:0031594 neuromuscular junction occurs_in UBERON:0000061 anatomical structure IMP
GO:0031594 neuromuscular junction FoldBasedPredictor GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential occurs_in GO:0031594 neuromuscular junction occurs_in UBERON:0000061 anatomical structure IMP
GO:0071499 cellular response to laminar fluid shear stress FoldBasedPredictor GO:1903038 negative regulation of leukocyte cell-cell adhesion occurs_in CL:0002544 aortic endothelial cell part_of GO:0071499 cellular response to laminar fluid shear stress IMP
GO:0033267 axon part FoldBasedPredictor GO:0098793 presynapse part_of GO:0030424 axon part_of UBERON:0002037 cerebellum IDA
GO:0042583 chromaffin granule FoldBasedPredictor GO:0097159 organic cyclic compound binding occurs_in GO:0042583 chromaffin granule IDA
GO:0098684 photoreceptor ribbon synapse FoldBasedPredictor GO:0098831 presynaptic active zone cytoplasmic component part_of GO:0098684 photoreceptor ribbon synapse part_of UBERON:0000061 anatomical structure IDA

Predictions (experimental)