GORULE violations assigned by BHF-UCL

Contents

gorule-0000001 GAF lines are parsed according to GAF 2.2 specifications

gorule-0000005 IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations are not allowed for direct annotations to to 'protein binding ; GO:0005515 or GO:0005488 binding''

gorule-0000008 No annotations should be made to uninformative high level terms

gorule-0000015 Dual species taxon check

gorule-0000016 With/From: IC annotations require a With/From GO ID

gorule-0000020 Automatic repair of annotations to merged or obsoleted terms

gorule-0000027 Each identifier in GAF is valid

gorule-0000039 Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants

gorule-0000046 The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

gorule-0000061 Allowed gene product to term relations (gp2term)

MESSAGES

gorule-0000001

GAF lines are parsed according to GAF 2.2 specifications

• total: 9

messages

• WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS000075C8FA_9606 URS000075C8FA_9606 contributes_to GO:0003968 PMID:19701182 IDA F Homo sapiens (human) RNA component of mitochondrial RNA processing endoribonuclease (RMRP) enzymatic_RNA taxon:9606 20150218 BHF-UCL `
• WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS000075C8FA_9606 URS000075C8FA_9606 contributes_to GO:0098680 PMID:19701182 IDA F Homo sapiens (human) RNA component of mitochondrial RNA processing endoribonuclease (RMRP) enzymatic_RNA taxon:9606 20170213 BHF-UCL `
• WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS000075C8FA_9606 URS000075C8FA_9606 enables GO:0005515 PMID:19701182 IPI UniProtKB:O14746 F Homo sapiens (human) RNA component of mitochondrial RNA processing endoribonuclease (RMRP) enzymatic_RNA taxon:9606 20241115 BHF-UCL `
• WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS000075C8FA_9606 URS000075C8FA_9606 enables GO:0070182 PMID:19701182 IPI UniProtKB:O14746 F Homo sapiens (human) RNA component of mitochondrial RNA processing endoribonuclease (RMRP) enzymatic_RNA taxon:9606 20151117 BHF-UCL `
• WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS000075C8FA_9606 URS000075C8FA_9606 involved_in GO:0001172 PMID:19701182 IDA P Homo sapiens (human) RNA component of mitochondrial RNA processing endoribonuclease (RMRP) enzymatic_RNA taxon:9606 20150218 BHF-UCL `
• WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS000075C8FA_9606 URS000075C8FA_9606 involved_in GO:0030422 PMID:19701182 IDA P Homo sapiens (human) RNA component of mitochondrial RNA processing endoribonuclease (RMRP) enzymatic_RNA taxon:9606 20150219 BHF-UCL `
• WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS000075C8FA_9606 URS000075C8FA_9606 involved_in GO:0140745 PMID:19701182 IDA P Homo sapiens (human) RNA component of mitochondrial RNA processing endoribonuclease (RMRP) enzymatic_RNA taxon:9606 20220604 BHF-UCL `
• WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS000075C8FA_9606 URS000075C8FA_9606 located_in GO:0005739 PMID:19701182 TAS C Homo sapiens (human) RNA component of mitochondrial RNA processing endoribonuclease (RMRP) enzymatic_RNA taxon:9606 20150219 BHF-UCL `
• WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS000075C8FA_9606 URS000075C8FA_9606 part_of GO:1990572 PMID:19701182 IMP C Homo sapiens (human) RNA component of mitochondrial RNA processing endoribonuclease (RMRP) enzymatic_RNA taxon:9606 20150218 BHF-UCL `

gorule-0000005

IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations are not allowed for direct annotations to to 'protein binding ; GO:0005515 or GO:0005488 binding''

• total: 8

messages

• WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`MGI MGI:1277959 Dlg4 enables GO:0005515 GO_REF:0000024 ISS UniProtKB:P31016 F discs large MAGUK scaffold protein 4 Dlgh4|PSD-95|PSD95|SAP90|SAP90A protein NCBITaxon:10090 20131017 BHF-UCL MGI:MGI:1277959 `
• WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`MGI MGI:3613677 Shank1 enables GO:0005515 GO_REF:0000024 ISS UniProtKB:Q9WV48 F SH3 and multiple ankyrin repeat domains 1 protein NCBITaxon:10090 20131017 BHF-UCL MGI:MGI:3613677 `
• WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB Q92974 ARHGEF2 enables GO:0005515 GO_REF:0000024 ISS UniProtKB:Q865S3 F Rho guanine nucleotide exchange factor 2 ARHGEF2|KIAA0651|LFP40 protein taxon:9606 20210910 BHF-UCL UniProtKB:Q92974 `
• WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB Q9BYB0 SHANK3 enables GO:0005515 GO_REF:0000024 ISS UniProtKB:Q4ACU6 F SH3 and multiple ankyrin repeat domains protein 3 SHANK3|KIAA1650|PROSAP2|PSAP2 protein taxon:9606 20110218 BHF-UCL UniProtKB:Q9BYB0 `
• WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB Q9BYB0 SHANK3 enables GO:0005515 GO_REF:0000024 ISS UniProtKB:Q9JLU4 F SH3 and multiple ankyrin repeat domains protein 3 SHANK3|KIAA1650|PROSAP2|PSAP2 protein taxon:9606 20131017 BHF-UCL UniProtKB:Q9BYB0 `
• WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB Q9NQC8 IFT46 enables GO:0005515 GO_REF:0000024 ISS UniProtKB:A2T2X4 F Intraflagellar transport protein 46 homolog IFT46|C11orf2|C11orf60 protein taxon:9606 20110314 BHF-UCL UniProtKB:Q9NQC8 `
• WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB Q9Y366 IFT52 enables GO:0005515 GO_REF:0000024 ISS UniProtKB:Q946G4 F Intraflagellar transport protein 52 homolog IFT52|C20orf9|NGD5|CGI-53 protein taxon:9606 20110314 BHF-UCL UniProtKB:Q9Y366 `
• WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB Q9Y566 SHANK1 enables GO:0005515 GO_REF:0000024 ISS UniProtKB:Q9WV48 F SH3 and multiple ankyrin repeat domains protein 1 SHANK1 protein taxon:9606 20131017 BHF-UCL UniProtKB:Q9Y566 `

gorule-0000008

No annotations should be made to uninformative high level terms

• total: 6

messages

• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:96612 Itgb3 involved_in GO:0048858 PMID:16995821 IC GO:0005178 P integrin beta 3 CD61|platelet glycoprotein IIIa (GP3A) protein NCBITaxon:10090 20110218 BHF-UCL MGI:MGI:96612 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB O15530 PDPK1 located_in GO:0042995 PMID:22454520 IDA C 3-phosphoinositide-dependent protein kinase 1 PDPK1|PDK1 protein taxon:9606 20140512 BHF-UCL UniProtKB:O15530 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P08567 PLEK involved_in GO:0030030 PMID:9060471 IDA P Pleckstrin PLEK|P47 protein taxon:9606 20090305 BHF-UCL UniProtKB:P08567 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P12036 NEFH involved_in GO:0030031 PMID:17498690 TAS P Neurofilament heavy polypeptide NEFH|KIAA0845|NFH protein taxon:9606 20140304 BHF-UCL occurs_in(GO:0030424) UniProtKB:P12036 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P19174 PLCG1 located_in GO:0042995 PMID:22454520 IDA C 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 PLCG1|PLC1 protein taxon:9606 20140512 BHF-UCL UniProtKB:P19174 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P27708 CAD located_in GO:0042995 GO_REF:0000024 ISS UniProtKB:A0A8I5ZMM2 C Multifunctional protein CAD CAD protein taxon:9606 20250718 BHF-UCL UniProtKB:P27708 `

gorule-0000015

Dual species taxon check

• total: 2

messages

• WARNING - Violates GO Rule:GORULE:0000015: Dual species taxon check--`UniProtKB P46934 NEDD4 acts_upstream_of GO:0046755 PMID:15126635 IMP P E3 ubiquitin-protein ligase NEDD4 NEDD4|KIAA0093|NEDD4-1|RPF1|PIG53 protein taxon:9606|taxon:11926 20200203 BHF-UCL UniProtKB:P46934 `
• WARNING - Violates GO Rule:GORULE:0000015: Dual species taxon check--`UniProtKB Q92692 NECTIN2 involved_in GO:0019064 PMID:12915581 IDA P Nectin-2 NECTIN2|HVEB|PRR2|PVRL2 protein taxon:9606|taxon:10310 20081128 BHF-UCL UniProtKB:Q92692 `

gorule-0000016

With/From: IC annotations require a With/From GO ID

• total: 5

messages

• WARNING - Violates GO Rule:GORULE:0000016: All IC annotations should include a GO ID in the "With/From" column that is also different from the entry in the "GO ID" column--`MGI MGI:97362 Nos3 located_in GO:0005737 PMID:11732991 IC GO:0005737 C nitric oxide synthase 3, endothelial cell 2310065A03Rik|Nos-3|eNOS|ecNOS protein NCBITaxon:10090 20180821 BHF-UCL part_of(CL:0000115),part_of(UBERON:0011742),existence_overlaps(GO:0003180) MGI:MGI:97362 `
• WARNING - Violates GO Rule:GORULE:0000016: All IC annotations should include a GO ID in the "With/From" column that is also different from the entry in the "GO ID" column--`UniProtKB P14859 POU2F1 enables GO:0001228 PMID:25802280 IC F POU domain, class 2, transcription factor 1 POU2F1|OCT1|OTF1 protein taxon:9606 20220817 BHF-UCL part_of(GO:1902895),has_input(RNAcentral:URS00001DC04F_9606) UniProtKB:P14859 `
• WARNING - Violates GO Rule:GORULE:0000016: All IC annotations should include a GO ID in the "With/From" column that is also different from the entry in the "GO ID" column--`UniProtKB P14859 POU2F1 involved_in GO:1902895 PMID:25802280 IC P POU domain, class 2, transcription factor 1 POU2F1|OCT1|OTF1 protein taxon:9606 20220817 BHF-UCL has_input(RNAcentral:URS00001DC04F_9606) UniProtKB:P14859 `
• WARNING - Violates GO Rule:GORULE:0000016: All IC annotations should include a GO ID in the "With/From" column that is also different from the entry in the "GO ID" column--`UniProtKB P55317 FOXA1 enables GO:0001228 PMID:25802280 IC F Hepatocyte nuclear factor 3-alpha FOXA1|HNF3A|TCF3A protein taxon:9606 20220817 BHF-UCL has_input(RNAcentral:URS00001DC04F_9606),part_of(GO:1902895) UniProtKB:P55317 `
• WARNING - Violates GO Rule:GORULE:0000016: All IC annotations should include a GO ID in the "With/From" column that is also different from the entry in the "GO ID" column--`UniProtKB P55317 FOXA1 involved_in GO:1902895 PMID:25802280 IC P Hepatocyte nuclear factor 3-alpha FOXA1|HNF3A|TCF3A protein taxon:9606 20220817 BHF-UCL has_input(RNAcentral:URS00001DC04F_9606) UniProtKB:P55317 `

gorule-0000020

Automatic repair of annotations to merged or obsoleted terms

• total: 41

messages

• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI MGI:894293 Smad4 involved_in GO:0003251 PMID:21330551 IMP P SMAD family member 4 D18Wsu70e|DPC4|Dpc4|Madh4|Smad 4 protein NCBITaxon:10090 20121129 BHF-UCL MGI:MGI:894293 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q13485 SMAD4 involved_in GO:0003251 GO_REF:0000024 ISS UniProtKB:P97471 P SMAD family member 4 SMAD4|DPC4|MADH4 protein taxon:9606 20190129 BHF-UCL UniProtKB:Q13485 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI MGI:1095407 Bmpr2 involved_in GO:0003252 PMID:19409885 IMP P bone morphogenetic protein receptor type 2 2610024H22Rik|BMP-2|BMPR-II|BMPRII protein NCBITaxon:10090 20160727 BHF-UCL occurs_in(UBERON:0005623) MGI:MGI:1095407 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI MGI:97363 Notch1 involved_in GO:0003252 PMID:26491108 IDA P notch 1 9930111A19Rik|Mis6|Motch A|N1|Tan1|lin-12 protein NCBITaxon:10090 20180517 BHF-UCL occurs_in(UBERON:0002137),part_of(GO:0003180) MGI:MGI:97363 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI MGI:97363 Notch1 involved_in GO:0003252 PMID:26491108 IMP P notch 1 9930111A19Rik|Mis6|Motch A|N1|Tan1|lin-12 protein NCBITaxon:10090 20180517 BHF-UCL occurs_in(UBERON:0002146),part_of(GO:0003184) MGI:MGI:97363 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI MGI:97363 Notch1 involved_in GO:0003252 PMID:26491108 IMP P notch 1 9930111A19Rik|Mis6|Motch A|N1|Tan1|lin-12 protein NCBITaxon:10090 20181015 BHF-UCL occurs_in(UBERON:0011742),part_of(GO:0003180) MGI:MGI:97363 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB P46531 NOTCH1 involved_in GO:0003252 GO_REF:0000024 ISS UniProtKB:Q01705 P Neurogenic locus notch homolog protein 1 NOTCH1|TAN1 protein taxon:9606 20180517 BHF-UCL occurs_in(UBERON:0002137),part_of(GO:0003180) UniProtKB:P46531 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB P46531 NOTCH1 involved_in GO:0003252 GO_REF:0000024 ISS UniProtKB:Q01705 P Neurogenic locus notch homolog protein 1 NOTCH1|TAN1 protein taxon:9606 20180517 BHF-UCL occurs_in(UBERON:0002146),part_of(GO:0003184) UniProtKB:P46531 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q13873 BMPR2 involved_in GO:0003252 GO_REF:0000024 ISS UniProtKB:O35607 P Bone morphogenetic protein receptor type-2 BMPR2|PPH1 protein taxon:9606 20160727 BHF-UCL occurs_in(UBERON:0005623) UniProtKB:Q13873 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI MGI:96982 Mif involved_in GO:0061078 PMID:11756671 IMP P macrophage migration inhibitory factor (glycosylation-inhibiting factor) Glif protein NCBITaxon:10090 20100524 BHF-UCL MGI:MGI:96982 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q96G23 CERS2 involved_in GO:1905045 GO_REF:0000024 ISS UniProtKB:Q3T1K1 P Ceramide synthase 2 CERS2|LASS2|TMSG1 protein taxon:9606 20160311 BHF-UCL UniProtKB:Q96G23 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`RGD 2325451 Mir221 involved_in GO:1905046 PMID:22393241 IDA P microRNA 221 miRNA NCBITaxon:10116 20160311 BHF-UCL `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`RGD 2325544 Mir222 involved_in GO:1905046 PMID:22393241 IDA P microRNA 222 miRNA NCBITaxon:10116 20160311 BHF-UCL `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`RNAcentral URS0000170CF4_9606 hsa-miR-221-3p involved_in GO:1905046 GO_REF:0000024 ISS RNAcentral:URS0000170CF4_10116 P Homo sapiens (human) hsa-miR-221-3p miRNA taxon:9606 20160311 BHF-UCL `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`RNAcentral URS00002C6949_9606 hsa-miR-222-3p involved_in GO:1905046 GO_REF:0000024 ISS RNAcentral:URS00002C6949_10116 P Homo sapiens (human) hsa-miR-222-3p miRNA taxon:9606 20160311 BHF-UCL `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`RGD 4888616 Mir182 involved_in GO:0035278 PMID:28259995 IDA P microRNA 182 miRNA NCBITaxon:10116 20180509 BHF-UCL has_input(UniProtKB:P36364),occurs_in(CL:0000359),negatively_regulates(GO:1905420) `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`RNAcentral URS000026261D_9606 hsa-miR-140-5p involved_in GO:0035195 PMID:27021683 IDA P Homo sapiens (human) hsa-miR-140-5p miRNA taxon:9606 20180326 BHF-UCL has_input(UniProtKB:P26358),occurs_in(CL:0002591),positively_regulates(GO:1905420)|has_input(UniProtKB:P26358),occurs_in(CL:0002591),negatively_regulates(GO:1990874)|has_input(UniProtKB:P26358),occurs_in(CL:0002591),positively_regulates(GO:1905288) `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`RGD 2610 Fgf9 involved_in GO:1905931 PMID:28259995 IMP P fibroblast growth factor 9 protein NCBITaxon:10116 20180509 BHF-UCL RGD:2610 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB P26358 DNMT1 involved_in GO:1905931 PMID:27021683 IMP P DNA (cytosine-5)-methyltransferase 1 DNMT1|AIM|CXXC9|DNMT protein taxon:9606 20180326 BHF-UCL part_of(GO:0071456),occurs_in(CL:0002591) UniProtKB:P26358 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB P31371 FGF9 involved_in GO:1905931 GO_REF:0000024 ISS UniProtKB:P36364 P Fibroblast growth factor 9 FGF9 protein taxon:9606 20180509 BHF-UCL UniProtKB:P31371 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`RGD 2325396 Mir18a involved_in GO:1905932 PMID:25089138 IDA P microRNA 18a miRNA NCBITaxon:10116 20230704 BHF-UCL occurs_in(CL:0000359) `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB P04179 SOD2 involved_in GO:1905932 PMID:27021683 IDA P Superoxide dismutase [Mn], mitochondrial SOD2 protein taxon:9606 20180326 BHF-UCL occurs_in(CL:0002591) UniProtKB:P04179 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`RNAcentral URS000026261D_9606 hsa-miR-140-5p involved_in GO:1905932 PMID:27021683 IDA P Homo sapiens (human) hsa-miR-140-5p miRNA taxon:9606 20180326 BHF-UCL part_of(GO:0071456),occurs_in(CL:0002591) `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`RNAcentral URS000035CC3E_9606 hsa-miR-18a-5p involved_in GO:1905932 GO_REF:0000024 ISS RNAcentral:URS000035CC3E_10116 P Homo sapiens (human) hsa-miR-18a-5p miRNA taxon:9606 20230704 BHF-UCL occurs_in(CL:0000359) `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB O94925 GLS involved_in GO:0006537 PMID:21757002 TAS P Glutaminase kidney isoform, mitochondrial GLS|GLS1|KIAA0838 protein taxon:9606 20111201 BHF-UCL UniProtKB:O94925 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB P00367 GLUD1 involved_in GO:0006537 PMID:11032875 IDA P Glutamate dehydrogenase 1, mitochondrial GLUD1|GLUD protein taxon:9606 20090616 BHF-UCL UniProtKB:P00367 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB P49448 GLUD2 involved_in GO:0006537 PMID:11032875 IDA P Glutamate dehydrogenase 2, mitochondrial GLUD2|GLUDP1 protein taxon:9606 20090616 BHF-UCL UniProtKB:P49448 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB Q04609 FOLH1 enables GO:0004181 PMID:17241121 IDA F Glutamate carboxypeptidase 2 FOLH1|FOLH|NAALAD1|PSM|PSMA|GIG27 protein taxon:9606 20250416 BHF-UCL has_input(CHEBI:73688),part_of(GO:0006537),occurs_in(UBERON:0000955)|has_input(CHEBI:73688),part_of(GO:0006537),occurs_in(UBERON:0002108)|has_input(CHEBI:73688),part_of(GO:0006537),occurs_in(UBERON:0002367) UniProtKB:Q04609 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB Q04609 FOLH1 enables GO:0004181 PMID:17241121 IDA F Glutamate carboxypeptidase 2 FOLH1|FOLH|NAALAD1|PSM|PSMA|GIG27 protein taxon:9606 20250416 BHF-UCL has_input(CHEBI:73688),part_of(GO:0006537),occurs_in(UBERON:0000955)|has_input(CHEBI:73688),part_of(GO:0006537),occurs_in(UBERON:0002108)|has_input(CHEBI:73688),part_of(GO:0006537),occurs_in(UBERON:0002367) UniProtKB:Q04609 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB Q04609 FOLH1 enables GO:0004181 PMID:17241121 IDA F Glutamate carboxypeptidase 2 FOLH1|FOLH|NAALAD1|PSM|PSMA|GIG27 protein taxon:9606 20250416 BHF-UCL has_input(CHEBI:73688),part_of(GO:0006537),occurs_in(UBERON:0000955)|has_input(CHEBI:73688),part_of(GO:0006537),occurs_in(UBERON:0002108)|has_input(CHEBI:73688),part_of(GO:0006537),occurs_in(UBERON:0002367) UniProtKB:Q04609 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB Q04609 FOLH1 involved_in GO:0006537 PMID:17241121 IDA P Glutamate carboxypeptidase 2 FOLH1|FOLH|NAALAD1|PSM|PSMA|GIG27 protein taxon:9606 20250416 BHF-UCL causally_upstream_of(GO:1900451) UniProtKB:Q04609 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB Q15758 SLC1A5 enables GO:0015186 PMID:21757002 TAS F Neutral amino acid transporter B(0) SLC1A5|ASCT2|M7V1|RDR|RDRC protein taxon:9606 20250924 BHF-UCL occurs_in(CL:0019026),causally_upstream_of(GO:0006537),part_of(GO:1903803) UniProtKB:Q15758 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB Q15758 SLC1A5 involved_in GO:1903803 PMID:21757002 TAS P Neutral amino acid transporter B(0) SLC1A5|ASCT2|M7V1|RDR|RDRC protein taxon:9606 20250924 BHF-UCL occurs_in(CL:0019026),causally_upstream_of(GO:0006537) UniProtKB:Q15758 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB Q9HBA9 FOLH1B enables GO:0004181 PMID:17241121 IDA F Putative N-acetylated-alpha-linked acidic dipeptidase FOLH1B|PSMAL|GIG26 protein taxon:9606 20250416 BHF-UCL has_input(CHEBI:73688),part_of(GO:0006537),occurs_in(UBERON:0000955)|has_input(CHEBI:73688),part_of(GO:0006537),occurs_in(UBERON:0002108)|has_input(CHEBI:73688),part_of(GO:0006537),occurs_in(UBERON:0002367) UniProtKB:Q9HBA9 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB Q9HBA9 FOLH1B enables GO:0004181 PMID:17241121 IDA F Putative N-acetylated-alpha-linked acidic dipeptidase FOLH1B|PSMAL|GIG26 protein taxon:9606 20250416 BHF-UCL has_input(CHEBI:73688),part_of(GO:0006537),occurs_in(UBERON:0000955)|has_input(CHEBI:73688),part_of(GO:0006537),occurs_in(UBERON:0002108)|has_input(CHEBI:73688),part_of(GO:0006537),occurs_in(UBERON:0002367) UniProtKB:Q9HBA9 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB Q9HBA9 FOLH1B enables GO:0004181 PMID:17241121 IDA F Putative N-acetylated-alpha-linked acidic dipeptidase FOLH1B|PSMAL|GIG26 protein taxon:9606 20250416 BHF-UCL has_input(CHEBI:73688),part_of(GO:0006537),occurs_in(UBERON:0000955)|has_input(CHEBI:73688),part_of(GO:0006537),occurs_in(UBERON:0002108)|has_input(CHEBI:73688),part_of(GO:0006537),occurs_in(UBERON:0002367) UniProtKB:Q9HBA9 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB Q9HBA9 FOLH1B involved_in GO:0006537 PMID:17241121 IDA P Putative N-acetylated-alpha-linked acidic dipeptidase FOLH1B|PSMAL|GIG26 protein taxon:9606 20250416 BHF-UCL causally_upstream_of(GO:1900451) UniProtKB:Q9HBA9 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB P15104 GLUL involved_in GO:0006542 PMID:21757002 TAS P Glutamine synthetase GLUL|GLNS protein taxon:9606 20111201 BHF-UCL UniProtKB:P15104 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB P43004 SLC1A2 involved_in GO:0098712 PMID:21757002 TAS P Excitatory amino acid transporter 2 SLC1A2|EAAT2|GLT1 protein taxon:9606 20250924 BHF-UCL occurs_in(CL:0000182),causally_upstream_of(GO:0006542) UniProtKB:P43004 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB P43007 SLC1A4 involved_in GO:0098712 PMID:21757002 TAS P Neutral amino acid transporter A SLC1A4|ASCT1|SATT protein taxon:9606 20250924 BHF-UCL occurs_in(CL:0000182),causally_upstream_of(GO:0006542) UniProtKB:P43007 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB Q9BYV1 AGXT2 involved_in GO:0019481 PMID:20018850 IDA P Alanine--glyoxylate aminotransferase 2, mitochondrial AGXT2|AGT2 protein taxon:9606 20120523 BHF-UCL UniProtKB:Q9BYV1 `

gorule-0000027

Each identifier in GAF is valid

• total: 2

messages

• WARNING - Invalid identifier:GORULE:0000027: ZDB-PUB-150609-8 does not match any id_syntax patterns for ZFIN in dbxrefs--`ZFIN ZDB-GENE-040611-1 nrp1b involved_in GO:0051491 PMID:26051942|ZFIN:ZDB-PUB-150609-8 IGI ZFIN:ZDB-GENE-030519-2 P neuropilin 1b protein_coding_gene taxon:7955 20170726 BHF-UCL part_of(GO:0090050)|part_of(GO:0038189)|part_of(GO:0007229) `
• WARNING - Invalid identifier:GORULE:0000027: ZDB-PUB-150609-8 does not match any id_syntax patterns for ZFIN in dbxrefs--`ZFIN ZDB-GENE-040611-1 nrp1b involved_in GO:0090050 PMID:26051942|ZFIN:ZDB-PUB-150609-8 IGI ZFIN:ZDB-GENE-030519-2 P neuropilin 1b protein_coding_gene taxon:7955 20170726 BHF-UCL part_of(GO:0038189)|part_of(GO:0007229) `

gorule-0000039

Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants

• total: 1

messages

• ERROR - Violates GO Rule:GORULE:0000039: Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants--`ComplexPortal CPX-19 tert-terc_mouse part_of GO:0000333 PMID:16037417 IMP C Telomerase catalytic core complex 2xTert:2xTerc protein_complex taxon:10090 20150217 BHF-UCL `

gorule-0000046

The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

• total: 71

messages

• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:103577 Hand1 enables GO:0042803 PMID:10924525 IPI UniProtKB:Q64279 F heart and neural crest derivatives expressed 1 Ehand1|Hxt|Th1|Thing1|bHLHa27|eHAND protein NCBITaxon:10090 20090826 BHF-UCL MGI:MGI:103577 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:103580 Hand2 enables GO:0042803 PMID:11812799 IPI UniProtKB:Q61039 F heart and neural crest derivatives expressed 2 Ehand2|Hed|Thing2|bHLHa26|dHAND protein NCBITaxon:10090 20090827 BHF-UCL MGI:MGI:103580 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:108050 Ext2 enables GO:0042803 PMID:10639137 IDA F exostosin glycosyltransferase 2 protein NCBITaxon:10090 20080228 BHF-UCL MGI:MGI:108050 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1195972 Terf2 enables GO:0042803 PMID:9326950 IPI UniProtKB:O35144 F telomeric repeat binding factor 2 TRF2 protein NCBITaxon:10090 20081216 BHF-UCL MGI:MGI:1195972 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1201414 Cer1 enables GO:0042803 PMID:10748465 IDA F cerberus 1, DAN family BMP antagonist Cerberus-like|Cerl|Cerl1|Cerr1|cer-1 protein NCBITaxon:10090 20120213 BHF-UCL MGI:MGI:1201414 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1270845 Cidea enables GO:0042803 PMID:17080483 IDA F cell death-inducing DNA fragmentation factor, alpha subunit-like effector A protein NCBITaxon:10090 20071212 BHF-UCL MGI:MGI:1270845 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1277234 Tbx15 enables GO:0042803 PMID:17584735 IPI UniProtKB:O70306 F T-box 15 Tbx14|Tbx8|de protein NCBITaxon:10090 20191030 BHF-UCL MGI:MGI:1277234 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1339753 Csf1 enables GO:0042803 PMID:19017797 IPI UniProtKB:P07141 F colony stimulating factor 1 (macrophage) BAP025|CSF-1|Csfm|M-CSF|colony-stimulating factor-1 protein NCBITaxon:10090 20100311 BHF-UCL MGI:MGI:1339753 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1339758 Csf1r enables GO:0042803 PMID:19017797 IPI UniProtKB:P09581 F colony stimulating factor 1 receptor CD115|CSF-1R|Csfmr|Fim-2|Fim2|Fms|M-CSFR protein NCBITaxon:10090 20090115 BHF-UCL MGI:MGI:1339758 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1351322 Mixl1 enables GO:0042803 PMID:22164283 IPI UniProtKB:Q9WUI0 F Mix paired-like homeobox Mml protein NCBITaxon:10090 20121029 BHF-UCL MGI:MGI:1351322 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1859544 Syt6 enables GO:0042803 PMID:10531343 IDA F synaptotagmin VI 3110037A08Rik protein NCBITaxon:10090 20110630 BHF-UCL MGI:MGI:1859544 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1859546 Syt10 enables GO:0042803 PMID:10531343 IDA F synaptotagmin X protein NCBITaxon:10090 20110630 BHF-UCL MGI:MGI:1859546 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1915050 Dgat2 enables GO:0042803 PMID:21680734 IPI UniProtKB:Q9DCV3 F diacylglycerol O-acyltransferase 2 0610010B06Rik protein NCBITaxon:10090 20111130 BHF-UCL MGI:MGI:1915050 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1923615 Tbx18 enables GO:0042803 PMID:17584735 IPI UniProtKB:Q9EPZ6 F T-box18 2810012F10Rik|2810404D13Rik protein NCBITaxon:10090 20191030 BHF-UCL MGI:MGI:1923615 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1930704 Bhlhe41 enables GO:0042803 PMID:17487425 IPI UniProtKB:Q99PV5 F basic helix-loop-helix family, member e41 6430520M22Rik|Bhlhb3|DEC2|Sharp1 protein NCBITaxon:10090 20111216 BHF-UCL MGI:MGI:1930704 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:2149946 Gopc enables GO:0042803 PMID:11520064 IPI UniProtKB:Q8BH60 F golgi associated PDZ and coiled-coil motif containing 2210402P09Rik|GOPC1 protein NCBITaxon:10090 20110330 BHF-UCL MGI:MGI:2149946 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:2180781 Slc8b1 enables GO:0042803 PMID:20018762 IPI UniProtKB:Q925Q3 F solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 NCKX6|NCLX|Slc24a6 protein NCBITaxon:10090 20140904 BHF-UCL occurs_in(UBERON:0000948)|occurs_in(UBERON:0000955) MGI:MGI:2180781 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:2442682 Slc30a8 enables GO:0042803 PMID:19095428 IPI UniProtKB:Q8BGG0 F solute carrier family 30 (zinc transporter), member 8 C820002P14Rik|ZnT-8|ZnT8 protein NCBITaxon:10090 20100128 BHF-UCL MGI:MGI:2442682 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:95392 Eng enables GO:0042803 PMID:8194490 IPI UniProtKB:Q63961 F endoglin CD105|Endo protein NCBITaxon:10090 20081107 BHF-UCL MGI:MGI:95392 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:97361 Nos2 enables GO:0042803 PMID:9271491 IDA F nitric oxide synthase 2, inducible NOS-II|Nos-2|Nos2a|iNOS protein NCBITaxon:10090 20080725 BHF-UCL MGI:MGI:97361 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:99665 Syt3 enables GO:0042803 PMID:10531343 IDA F synaptotagmin III protein NCBITaxon:10090 20110630 BHF-UCL MGI:MGI:99665 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`RGD 1565818 Slc8b1 enables GO:0042803 PMID:20018762 IPI UniProtKB:Q6AXS0 F solute carrier family 8 member B1 protein NCBITaxon:10116 20140904 BHF-UCL occurs_in(UBERON:0000948) RGD:1565818 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`RGD 2276 Casq2 enables GO:0042803 PMID:20353949 IDA F calsequestrin 2 protein NCBITaxon:10116 20120620 BHF-UCL RGD:2276 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`RGD 61916 Fzd1 enables GO:0042803 PMID:14688793 IPI UniProtKB:Q08463 F frizzled class receptor 1 protein NCBITaxon:10116 20100803 BHF-UCL RGD:61916 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB O14503 BHLHE40 enables GO:0042803 PMID:15560782 IDA F Class E basic helix-loop-helix protein 40 BHLHE40|BHLHB2|DEC1|SHARP2|STRA13 protein taxon:9606 20111114 BHF-UCL UniProtKB:O14503 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB O14746 TERT enables GO:0042803 PMID:11432839 IDA F Telomerase reverse transcriptase TERT|EST2|TCS1|TRT protein taxon:9606 20081219 BHF-UCL UniProtKB:O14746 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB O43353 RIPK2 enables GO:0042803 PMID:19337385 IDA F Receptor-interacting serine/threonine-protein kinase 2 RIPK2|CARDIAK|RICK|RIP2|UNQ277/PRO314/PRO34092 protein taxon:9606 20110124 BHF-UCL UniProtKB:O43353 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P01127 PDGFB enables GO:0042803 PMID:2836953 IDA F Platelet-derived growth factor subunit B PDGFB|PDGF2|SIS protein taxon:9606 20080428 BHF-UCL UniProtKB:P01127 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P02652 APOA2 enables GO:0042803 PMID:17264082 IDA F Apolipoprotein A-II APOA2 protein taxon:9606 20080104 BHF-UCL UniProtKB:P02652 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P04085 PDGFA enables GO:0042803 PMID:2836953 IDA F Platelet-derived growth factor subunit A PDGFA|PDGF1 protein taxon:9606 20080428 BHF-UCL UniProtKB:P04085 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P04085 PDGFA enables GO:0042803 PMID:3754619 IDA F Platelet-derived growth factor subunit A PDGFA|PDGF1 protein taxon:9606 20080428 BHF-UCL UniProtKB:P04085 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P06727 APOA4 enables GO:0042803 PMID:1935934 IDA F Apolipoprotein A-IV APOA4 protein taxon:9606 20080107 BHF-UCL UniProtKB:P06727 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P08567 PLEK enables GO:0042803 PMID:8694752 IDA F Pleckstrin PLEK|P47 protein taxon:9606 20090305 BHF-UCL UniProtKB:P08567 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P08913 ADRA2A enables GO:0042803 PMID:16605244 IDA F Alpha-2A adrenergic receptor ADRA2A|ADRA2R|ADRAR protein taxon:9606 20100630 BHF-UCL UniProtKB:P08913 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P09603 CSF1 enables GO:0042803 PMID:3264878 IDA F Macrophage colony-stimulating factor 1 CSF1 protein taxon:9606 20090115 BHF-UCL UniProtKB:P09603 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P10912 GHR enables GO:0042803 PMID:1549776 IDA F Growth hormone receptor GHR protein taxon:9606 20081205 BHF-UCL UniProtKB:P10912 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P10912 GHR enables GO:0042803 PMID:8137822 IDA F Growth hormone receptor GHR protein taxon:9606 20081205 BHF-UCL UniProtKB:P10912 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P16234 PDGFRA enables GO:0042803 PMID:2542288 IDA F Platelet-derived growth factor receptor alpha PDGFRA|PDGFR2|RHEPDGFRA protein taxon:9606 20080429 BHF-UCL UniProtKB:P16234 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P17813 ENG enables GO:0042803 PMID:8370410 IPI UniProtKB:P17813-2 F Endoglin ENG|END protein taxon:9606 20081109 BHF-UCL UniProtKB:P17813-2 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P18825 ADRA2C enables GO:0042803 PMID:16605244 IDA F Alpha-2C adrenergic receptor ADRA2C|ADRA2L2|ADRA2RL2 protein taxon:9606 20100630 BHF-UCL UniProtKB:P18825 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P21333 FLNA enables GO:0042803 PMID:2391361 IDA F Filamin-A FLNA|FLN|FLN1 protein taxon:9606 20080914 BHF-UCL UniProtKB:P21333 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P22413 ENPP1 enables GO:0042803 PMID:7830796 IDA F Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 ENPP1|M6S1|NPPS|PC1|PDNP1 protein taxon:9606 20080225 BHF-UCL UniProtKB:P22413 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P23497 SP100 enables GO:0042803 PMID:9636146 IPI UniProtKB:P23497-1 F Nuclear autoantigen Sp-100 SP100 protein taxon:9606 20100311 BHF-UCL UniProtKB:P23497-1 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P23497 SP100 enables GO:0042803 PMID:9636146 IPI UniProtKB:P23497-2 F Nuclear autoantigen Sp-100 SP100 protein taxon:9606 20081022 BHF-UCL UniProtKB:P23497-2 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P36894 BMPR1A enables GO:0042803 PMID:18436533 IDA F Bone morphogenetic protein receptor type-1A BMPR1A|ACVRLK3|ALK3 protein taxon:9606 20080613 BHF-UCL UniProtKB:P36894 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P41235 HNF4A enables GO:0042803 PMID:12220494 IDA F Hepatocyte nuclear factor 4-alpha HNF4A|HNF4|NR2A1|TCF14 protein taxon:9606 20080421 BHF-UCL UniProtKB:P41235 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P45844 ABCG1 enables GO:0042803 PMID:16870176 IDA F ATP-binding cassette sub-family G member 1 ABCG1|ABC8|WHT1 protein taxon:9606 20071206 BHF-UCL UniProtKB:P45844 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P47992 XCL1 enables GO:0042803 PMID:11889129 IDA F Lymphotactin XCL1|LTN|SCYC1 protein taxon:9606 20110315 BHF-UCL UniProtKB:P47992 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P63316 TNNC1 enables GO:0042803 PMID:18092822 IDA F Troponin C, slow skeletal and cardiac muscles TNNC1|TNNC protein taxon:9606 20080512 BHF-UCL UniProtKB:P63316 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q04771 ACVR1 enables GO:0042803 PMID:18436533 IDA F Activin receptor type-1 ACVR1|ACVRLK2 protein taxon:9606 20080613 BHF-UCL UniProtKB:Q04771 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q13253 NOG enables GO:0042803 PMID:11562478 IDA F Noggin NOG protein taxon:9606 20080711 BHF-UCL UniProtKB:Q13253 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q13563 PKD2 enables GO:0042803 PMID:9192675 IDA F Polycystin-2 PKD2|TRPP1|TRPP2 protein taxon:9606 20120112 BHF-UCL UniProtKB:Q13563 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q16394 EXT1 enables GO:0042803 PMID:12907669 IDA F Exostosin-1 EXT1 protein taxon:9606 20080228 BHF-UCL UniProtKB:Q16394 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q6UB35 MTHFD1L enables GO:0042803 PMID:16171773 IDA F Monofunctional C1-tetrahydrofolate synthase, mitochondrial MTHFD1L|FTHFSDC1 protein taxon:9606 20090720 BHF-UCL UniProtKB:Q6UB35 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q86XE5 HOGA1 enables GO:0042803 PMID:21998747 IDA F 4-hydroxy-2-oxoglutarate aldolase, mitochondrial HOGA1|C10orf65|DHDPSL protein taxon:9606 20120710 BHF-UCL UniProtKB:Q86XE5 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q8IW40 DNAAF19 enables GO:0042803 PMID:22581229 IDA F Dynein axonemal assembly factor 19 DNAAF19|CCDC103 protein taxon:9606 20120726 BHF-UCL occurs_in(CL:0002368) UniProtKB:Q8IW40 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q8WYQ5 DGCR8 enables GO:0042803 PMID:15574589 IDA F Microprocessor complex subunit DGCR8 DGCR8|C22orf12|DGCRK6|LP4941 protein taxon:9606 20150115 BHF-UCL UniProtKB:Q8WYQ5 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q92600 CNOT9 enables GO:0042803 PMID:24768540 IDA F CCR4-NOT transcription complex subunit 9 CNOT9|RCD1|RQCD1 protein taxon:9606 20141222 BHF-UCL UniProtKB:Q92600 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q92692 NECTIN2 enables GO:0042803 PMID:9845526 IPI UniProtKB:Q92692-1 F Nectin-2 NECTIN2|HVEB|PRR2|PVRL2 protein taxon:9606 20081128 BHF-UCL UniProtKB:Q92692-1 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q92692 NECTIN2 enables GO:0042803 PMID:9845526 IPI UniProtKB:Q92692-2 F Nectin-2 NECTIN2|HVEB|PRR2|PVRL2 protein taxon:9606 20081128 BHF-UCL UniProtKB:Q92692-2 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q93063 EXT2 NOT|enables GO:0042803 PMID:12907669 IDA F Exostosin-2 EXT2 protein taxon:9606 20080228 BHF-UCL UniProtKB:Q93063 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q96BF6 NACC2 enables GO:0042803 PMID:22926524 IDA F Nucleus accumbens-associated protein 2 NACC2|BTBD14A|NAC2|RBB protein taxon:9606 20121129 BHF-UCL UniProtKB:Q96BF6 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q99697 PITX2 enables GO:0042803 PMID:12612071 IPI UniProtKB:Q99697-3 F Pituitary homeobox 2 PITX2|ARP1|RGS|RIEG|RIEG1 protein taxon:9606 20110922 BHF-UCL UniProtKB:Q99697-3 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q99697 PITX2 enables GO:0042803 PMID:19174163 IPI UniProtKB:Q99697-2 F Pituitary homeobox 2 PITX2|ARP1|RGS|RIEG|RIEG1 protein taxon:9606 20111012 BHF-UCL UniProtKB:Q99697-2 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q9H172 ABCG4 enables GO:0042803 PMID:16870176 IDA F ATP-binding cassette sub-family G member 4 ABCG4|WHITE2 protein taxon:9606 20071206 BHF-UCL UniProtKB:Q9H172 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q9H816 DCLRE1B enables GO:0042803 PMID:20479256 IDA F 5' exonuclease Apollo DCLRE1B|SNM1B protein taxon:9606 20161212 BHF-UCL UniProtKB:Q9H816 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q9NP71 MLXIPL NOT|enables GO:0042803 PMID:11230181 IDA F Carbohydrate-responsive element-binding protein MLXIPL|BHLHD14|MIO|WBSCR14 protein taxon:9606 20080307 BHF-UCL UniProtKB:Q9NP71 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q9NRR4 DROSHA enables GO:0042803 PMID:15574589 IDA F Ribonuclease 3 DROSHA|RN3|RNASE3L|RNASEN protein taxon:9606 20150115 BHF-UCL UniProtKB:Q9NRR4 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q9UNQ0 ABCG2 enables GO:0042803 PMID:16870176 IDA F Broad substrate specificity ATP-binding cassette transporter ABCG2 ABCG2|ABCP|BCRP|BCRP1|MXR protein taxon:9606 20071206 BHF-UCL UniProtKB:Q9UNQ0 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q9Y2Z4 YARS2 enables GO:0042803 PMID:15779907 IPI UniProtKB:Q6PI48 F Tyrosine--tRNA ligase, mitochondrial YARS2|CGI-04 protein taxon:9606 20110718 BHF-UCL UniProtKB:Q9Y2Z4 `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P15691 VEGFA enables GO:0042803 PMID:2798412 IDA F Vascular endothelial growth factor A VEGFA|VEGF protein taxon:9913 20080731 BHF-UCL UniProtKB:P15691 `

gorule-0000061

Allowed gene product to term relations (gp2term)

• total: 5

messages

• WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: BFO:0000050 should be one of RO:0002325, RO:0002432, RO:0001025. Repaired to RO:0001025--`UniProtKB O60716 CTNND1 part_of GO:0005912 PMID:20123964 IDA C Catenin delta-1 CTNND1|KIAA0384 protein taxon:9606 20241217 BHF-UCL part_of(CL:0000115) UniProtKB:O60716 `
• WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0001025 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB P25686 DNAJB2 located_in GO:0000502 PMID:15936278 IDA C DnaJ homolog subfamily B member 2 DNAJB2|HSJ1|HSPF3 protein taxon:9606 20231121 BHF-UCL UniProtKB:P25686-2 `
• WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: BFO:0000050 should be one of RO:0002325, RO:0002432, RO:0001025. Repaired to RO:0001025--`UniProtKB P35222 CTNNB1 part_of GO:0005829 PMID:20123964 IDA C Catenin beta-1 CTNNB1|CTNNB|OK/SW-cl.35|PRO2286 protein taxon:9606 20241217 BHF-UCL part_of(CL:0000115) UniProtKB:P35222 `
• WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: BFO:0000050 should be one of RO:0002325, RO:0002432, RO:0001025. Repaired to RO:0001025--`UniProtKB Q15848 ADIPOQ part_of GO:0005576 PMID:11222466 IDA C Adiponectin ADIPOQ|ACDC|ACRP30|APM1|GBP28 protein taxon:9606 20241115 BHF-UCL UniProtKB:Q15848 `
• WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB Q7KZN9 COX15 is_active_in GO:0070069 PMID:12474143 IDA C Heme A synthase COX15 COX15 protein taxon:9606 20240209 BHF-UCL UniProtKB:Q7KZN9 `