Table of contents

Report

Group: paint - Dataset: paint_cgd

SUMMARY

This report generated on 2026-05-08

Header From Original Association File

!gaf-version: 2.2
!Created on Mon Jan 5 19:02:39 2026.
!generated-by: PANTHER
!date-generated: 2026-01-05
!PANTHER version: v.19.0.
!GO version: 2025-10-05.

Contents

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other

MESSAGES

gorule-0000002

No 'NOT' annotations to binding ; GO:0005488 or 'protein binding ; GO:0005515'

gorule-0000005

IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations are not allowed for direct annotations to 'protein binding ; GO:0005515 or GO:0005488 binding''

gorule-0000006

IEP and HEP usage is restricted to terms from the Biological Process ontology

gorule-0000007

IPI should not be used with GO:0003824 catalytic activity or descendents

gorule-0000008

No annotations should be made to uninformative high level terms

Messages

gorule-0000011

ND evidence code should be to root nodes only, and no terms other than root nodes can have the evidence code ND

gorule-0000013

Taxon-appropriate annotation check

Messages

gorule-0000015

Dual species taxon check

gorule-0000016

With/From: IC annotations require a With/From GO ID

gorule-0000017

IDA annotations must not have a With/From entry

gorule-0000018

IPI annotations require a With/From entry

gorule-0000020

Automatic repair of annotations to merged or obsoleted terms

Messages

gorule-0000022

Check for, and filter, annotations made to retracted publications

gorule-0000027

Each identifier in GAF is valid

Messages

gorule-0000028

GO aspect should match the term's namespace; otherwise it is repaired to the appropriate aspect

gorule-0000029

IEAs should be less than one year old.

gorule-0000030

Only valid GO_REFs are allowed

gorule-0000037

IBA annotations should ONLY be assigned_by GO_Central and have GO_REF:0000033 as a reference

gorule-0000039

Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants

gorule-0000042

Qualifier: IKR evidence code requires a NOT qualifier

gorule-0000043

Check for valid combination of evidence code, with/from rules and GO_REF

gorule-0000046

The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

Messages

gorule-0000050

Annotations to ISS, ISA and ISO should not be self-referential

gorule-0000055

References should have only one ID per ID space

gorule-0000058

Object extensions should conform to the extensions-patterns.yaml file in metadata

gorule-0000061

Allowed gene product to term relations (gp2term)

gorule-0000063

Annotations using ISS/ISA/ISO evidence should refer to a gene product (in the 'with' column)

gorule-0000064

TreeGrafter IEAs should be filtered for GO reference species

gorule-0000065

Annotations to term that are candidates for obsoletion should be produce a warning

other

Predictions

GO:1903830 magnesium ion transmembrane transport AnnotationPropagation P GO:0015095 magnesium ion transmembrane transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0032981 mitochondrial respiratory chain complex I assembly IBA
GO:0001522 pseudouridine synthesis AnnotationPropagation P GO:0004730 pseudouridylate synthase activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0045893 positive regulation of DNA-templated transcription AnnotationPropagation P GO:0003713 transcription coactivator activity IBA
GO:0061025 membrane fusion AnnotationPropagation P GO:0005484 SNAP receptor activity IBA
GO:0000165 MAPK cascade AnnotationPropagation P GO:0004708 MAP kinase kinase activity IBA
GO:1903830 magnesium ion transmembrane transport AnnotationPropagation P GO:0015095 magnesium ion transmembrane transporter activity IBA
GO:0035269 protein O-linked glycosylation via mannose AnnotationPropagation P GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity IBA
GO:0022904 respiratory electron transport chain AnnotationPropagation P GO:0004174 electron-transferring-flavoprotein dehydrogenase activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0034553 mitochondrial respiratory chain complex II assembly IBA
GO:0006366 transcription by RNA polymerase II AnnotationPropagation P GO:0016251 RNA polymerase II general transcription initiation factor activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0006390 mitochondrial transcription IBA
GO:0071806 protein transmembrane transport AnnotationPropagation P GO:0008320 transmembrane protein transporter activity IBA
GO:0045893 positive regulation of DNA-templated transcription AnnotationPropagation P GO:0003713 transcription coactivator activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0033617 mitochondrial respiratory chain complex IV assembly IBA
GO:0006383 transcription by RNA polymerase III AnnotationPropagation P GO:0000995 RNA polymerase III general transcription initiation factor activity IBA
GO:0006222 UMP biosynthetic process AnnotationPropagation P GO:0004849 uridine kinase activity IBA
GO:0098656 monoatomic anion transmembrane transport AnnotationPropagation P GO:0008308 voltage-gated monoatomic anion channel activity IBA
GO:0051170 import into nucleus AnnotationPropagation P GO:0061608 nuclear import signal receptor activity IBA
GO:0006457 protein folding AnnotationPropagation P GO:0044183 protein folding chaperone IBA
GO:0005829 cytosol AnnotationPropagation C GO:0042147 retrograde transport, endosome to Golgi IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0098655 monoatomic cation transmembrane transport AnnotationPropagation P GO:0005227 calcium-activated cation channel activity IBA
GO:0120009 intermembrane lipid transfer AnnotationPropagation P GO:0008526 phosphatidylinositol transfer activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0032981 mitochondrial respiratory chain complex I assembly IBA
GO:0036261 7-methylguanosine cap hypermethylation AnnotationPropagation P GO:0071164 RNA cap trimethylguanosine synthase activity IBA
GO:0035433 acetate transmembrane transport AnnotationPropagation P GO:0015123 acetate transmembrane transporter activity IBA
GO:0002943 tRNA dihydrouridine synthesis AnnotationPropagation P GO:0017150 tRNA dihydrouridine synthase activity IBA
GO:0005783 endoplasmic reticulum AnnotationPropagation C GO:0006621 protein retention in ER lumen IBA
GO:1902600 proton transmembrane transport AnnotationPropagation P GO:0015386 potassium:proton antiporter activity IBA
GO:0071805 potassium ion transmembrane transport AnnotationPropagation P GO:0015386 potassium:proton antiporter activity IBA
GO:0015746 citrate transport AnnotationPropagation P GO:0071913 citrate secondary active transmembrane transporter activity IBA
GO:0035674 tricarboxylic acid transmembrane transport AnnotationPropagation P GO:0071913 citrate secondary active transmembrane transporter activity IBA
GO:0006355 regulation of DNA-templated transcription AnnotationPropagation P GO:0003700 DNA-binding transcription factor activity IBA
GO:0019430 removal of superoxide radicals AnnotationPropagation P GO:0004784 superoxide dismutase activity IBA
GO:0015909 long-chain fatty acid transport AnnotationPropagation P GO:0005324 long-chain fatty acid transmembrane transporter activity IBA
GO:1905039 carboxylic acid transmembrane transport AnnotationPropagation P GO:0005324 long-chain fatty acid transmembrane transporter activity IBA
GO:0001676 long-chain fatty acid metabolic process AnnotationPropagation P GO:0004467 long-chain fatty acid-CoA ligase activity IBA
GO:0035433 acetate transmembrane transport AnnotationPropagation P GO:0015123 acetate transmembrane transporter activity IBA
GO:0007010 cytoskeleton organization AnnotationPropagation P GO:0005200 structural constituent of cytoskeleton IBA
GO:0006457 protein folding AnnotationPropagation P GO:0044183 protein folding chaperone IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0033617 mitochondrial respiratory chain complex IV assembly IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0051156 glucose 6-phosphate metabolic process AnnotationPropagation P GO:0004340 glucokinase activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0033617 mitochondrial respiratory chain complex IV assembly IBA
GO:0006338 chromatin remodeling AnnotationPropagation P GO:0042799 histone H4K20 methyltransferase activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0042407 cristae formation IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0098869 cellular oxidant detoxification AnnotationPropagation P GO:0008379 thioredoxin peroxidase activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0015205 nucleobase transmembrane transporter activity IBA
GO:0015851 nucleobase transport AnnotationPropagation P GO:0015205 nucleobase transmembrane transporter activity IBA
GO:0046710 GDP metabolic process AnnotationPropagation P GO:0004385 GMP kinase activity IBA
GO:0046037 GMP metabolic process AnnotationPropagation P GO:0004385 GMP kinase activity IBA
GO:0045944 positive regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0070124 mitochondrial translational initiation IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0042626 ATPase-coupled transmembrane transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0072670 mitochondrial tRNA threonylcarbamoyladenosine modification IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0070778 L-aspartate transmembrane transport AnnotationPropagation P GO:0015183 L-aspartate transmembrane transporter activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0071918 urea transmembrane transport AnnotationPropagation P GO:0015204 urea transmembrane transporter activity IBA
GO:0005634 nucleus AnnotationPropagation C GO:0071038 TRAMP-dependent tRNA surveillance pathway IBA
GO:0098655 monoatomic cation transmembrane transport AnnotationPropagation P GO:0005227 calcium-activated cation channel activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0005315 phosphate transmembrane transporter activity IBA
GO:0045893 positive regulation of DNA-templated transcription AnnotationPropagation P GO:0003713 transcription coactivator activity IBA
GO:0003333 amino acid transmembrane transport AnnotationPropagation P GO:0015171 amino acid transmembrane transporter activity IBA
GO:0071805 potassium ion transmembrane transport AnnotationPropagation P GO:0015079 potassium ion transmembrane transporter activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0035672 oligopeptide transmembrane transport AnnotationPropagation P GO:0035673 oligopeptide transmembrane transporter activity IBA
GO:0003333 amino acid transmembrane transport AnnotationPropagation P GO:0015171 amino acid transmembrane transporter activity IBA
GO:0006325 chromatin organization AnnotationPropagation P GO:0140566 histone reader activity IBA
GO:0015706 nitrate transmembrane transport AnnotationPropagation P GO:0015112 nitrate transmembrane transporter activity IBA
GO:0005773 vacuole AnnotationPropagation C GO:0006624 vacuolar protein processing IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0032981 mitochondrial respiratory chain complex I assembly IBA
GO:0005737 cytoplasm AnnotationPropagation C GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport IBA
GO:0008645 hexose transmembrane transport AnnotationPropagation P GO:0015149 hexose transmembrane transporter activity IBA
GO:0051168 nuclear export AnnotationPropagation P GO:0005049 nuclear export signal receptor activity IBA
GO:1902600 proton transmembrane transport AnnotationPropagation P GO:0005351 carbohydrate:proton symporter activity IBA
GO:0034219 carbohydrate transmembrane transport AnnotationPropagation P GO:0005351 carbohydrate:proton symporter activity IBA
GO:1904668 positive regulation of ubiquitin protein ligase activity AnnotationPropagation P GO:1990757 ubiquitin ligase activator activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0035672 oligopeptide transmembrane transport AnnotationPropagation P GO:0035673 oligopeptide transmembrane transporter activity IBA
GO:0003333 amino acid transmembrane transport AnnotationPropagation P GO:0015185 gamma-aminobutyric acid transmembrane transporter activity IBA
GO:0015812 gamma-aminobutyric acid transport AnnotationPropagation P GO:0015185 gamma-aminobutyric acid transmembrane transporter activity IBA
GO:1905039 carboxylic acid transmembrane transport AnnotationPropagation P GO:0015185 gamma-aminobutyric acid transmembrane transporter activity IBA
GO:0006355 regulation of DNA-templated transcription AnnotationPropagation P GO:0003700 DNA-binding transcription factor activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:1990180 mitochondrial tRNA 3'-end processing IBA
GO:0071918 urea transmembrane transport AnnotationPropagation P GO:0015204 urea transmembrane transporter activity IBA
GO:0006338 chromatin remodeling AnnotationPropagation P GO:0042800 histone H3K4 methyltransferase activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:1903711 spermidine transmembrane transport AnnotationPropagation P GO:0015606 spermidine transmembrane transporter activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0006338 chromatin remodeling AnnotationPropagation P GO:0010485 histone H4 acetyltransferase activity IBA
GO:1902600 proton transmembrane transport AnnotationPropagation P GO:0005351 carbohydrate:proton symporter activity IBA
GO:0034219 carbohydrate transmembrane transport AnnotationPropagation P GO:0005351 carbohydrate:proton symporter activity IBA
GO:0006657 CDP-choline pathway AnnotationPropagation P GO:0004103 choline kinase activity IBA
GO:0006338 chromatin remodeling AnnotationPropagation P GO:0017136 histone deacetylase activity, NAD-dependent IBA
GO:0005737 cytoplasm AnnotationPropagation C GO:0030970 retrograde protein transport, ER to cytosol IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0005315 phosphate transmembrane transporter activity IBA
GO:0005737 cytoplasm AnnotationPropagation C GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0015297 antiporter activity IBA
GO:0035349 coenzyme A transmembrane transport AnnotationPropagation P GO:0015228 coenzyme A transmembrane transporter activity IBA
GO:0005737 cytoplasm AnnotationPropagation C GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport IBA
GO:0005737 cytoplasm AnnotationPropagation C GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport IBA
GO:0051168 nuclear export AnnotationPropagation P GO:0005049 nuclear export signal receptor activity IBA
GO:0035352 NAD transmembrane transport AnnotationPropagation P GO:0051724 NAD transmembrane transporter activity IBA
GO:0071421 manganese ion transmembrane transport AnnotationPropagation P GO:0005384 manganese ion transmembrane transporter activity IBA
GO:0051156 glucose 6-phosphate metabolic process AnnotationPropagation P GO:0004340 glucokinase activity IBA
GO:0005829 cytosol AnnotationPropagation C GO:0042147 retrograde transport, endosome to Golgi IBA
GO:0045893 positive regulation of DNA-templated transcription AnnotationPropagation P GO:0001216 DNA-binding transcription activator activity IBA
GO:0015699 antimonite transmembrane transport AnnotationPropagation P GO:0015104 antimonite transmembrane transporter activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation IBA
GO:0006366 transcription by RNA polymerase II AnnotationPropagation P GO:0016251 RNA polymerase II general transcription initiation factor activity IBA
GO:0045944 positive regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific IBA
GO:0000160 phosphorelay signal transduction system AnnotationPropagation P GO:0000156 phosphorelay response regulator activity IBA
GO:0005737 cytoplasm AnnotationPropagation C GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport IBA
GO:0010498 proteasomal protein catabolic process AnnotationPropagation P GO:0036402 proteasome-activating activity IBA
GO:0045893 positive regulation of DNA-templated transcription AnnotationPropagation P GO:0001216 DNA-binding transcription activator activity IBA
GO:0106074 aminoacyl-tRNA metabolism involved in translational fidelity AnnotationPropagation P GO:0002196 Ser-tRNA(Ala) deacylase activity IBA
GO:0006338 chromatin remodeling AnnotationPropagation P GO:0004407 histone deacetylase activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0033617 mitochondrial respiratory chain complex IV assembly IBA
GO:0005737 cytoplasm AnnotationPropagation C GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport IBA
GO:0006338 chromatin remodeling AnnotationPropagation P GO:0017136 histone deacetylase activity, NAD-dependent IBA
GO:1902475 L-alpha-amino acid transmembrane transport AnnotationPropagation P GO:0015179 L-amino acid transmembrane transporter activity IBA
GO:0071918 urea transmembrane transport AnnotationPropagation P GO:0015204 urea transmembrane transporter activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0035433 acetate transmembrane transport AnnotationPropagation P GO:0015123 acetate transmembrane transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0045040 protein insertion into mitochondrial outer membrane IBA
GO:0006338 chromatin remodeling AnnotationPropagation P GO:0034647 histone H3K4me/H3K4me2/H3K4me3 demethylase activity IBA
GO:0009107 lipoate biosynthetic process AnnotationPropagation P GO:0016992 lipoate synthase activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0045040 protein insertion into mitochondrial outer membrane IBA
GO:0006415 translational termination AnnotationPropagation P GO:0016149 translation release factor activity, codon specific IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0033617 mitochondrial respiratory chain complex IV assembly IBA
GO:0006413 translational initiation AnnotationPropagation P GO:0003743 translation initiation factor activity IBA
GO:1902358 sulfate transmembrane transport AnnotationPropagation P GO:0015116 sulfate transmembrane transporter activity IBA
GO:0098655 monoatomic cation transmembrane transport AnnotationPropagation P GO:0005227 calcium-activated cation channel activity IBA
GO:0061025 membrane fusion AnnotationPropagation P GO:0005484 SNAP receptor activity IBA
GO:0006355 regulation of DNA-templated transcription AnnotationPropagation P GO:0003700 DNA-binding transcription factor activity IBA
GO:1901475 pyruvate transmembrane transport AnnotationPropagation P GO:0050833 pyruvate transmembrane transporter activity IBA
GO:0006413 translational initiation AnnotationPropagation P GO:0003743 translation initiation factor activity IBA
GO:0002943 tRNA dihydrouridine synthesis AnnotationPropagation P GO:0017150 tRNA dihydrouridine synthase activity IBA
GO:0015741 fumarate transport AnnotationPropagation P GO:0005469 succinate:fumarate antiporter activity IBA
GO:0071422 succinate transmembrane transport AnnotationPropagation P GO:0005469 succinate:fumarate antiporter activity IBA
GO:0071918 urea transmembrane transport AnnotationPropagation P GO:0015204 urea transmembrane transporter activity IBA
GO:1901475 pyruvate transmembrane transport AnnotationPropagation P GO:0050833 pyruvate transmembrane transporter activity IBA
GO:0005634 nucleus AnnotationPropagation C GO:0071028 nuclear mRNA surveillance IBA
GO:0006338 chromatin remodeling AnnotationPropagation P GO:0043998 histone H2A acetyltransferase activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0033617 mitochondrial respiratory chain complex IV assembly IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0008559 ABC-type xenobiotic transporter activity IBA
GO:0042908 xenobiotic transport AnnotationPropagation P GO:0008559 ABC-type xenobiotic transporter activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:1903401 L-lysine transmembrane transport AnnotationPropagation P GO:0015189 L-lysine transmembrane transporter activity IBA
GO:1990822 basic amino acid transmembrane transport AnnotationPropagation P GO:0015189 L-lysine transmembrane transporter activity IBA
GO:0042823 pyridoxal 5'-phosphate biosynthetic process AnnotationPropagation P GO:0004733 pyridoxamine phosphate oxidase activity IBA
GO:0035433 acetate transmembrane transport AnnotationPropagation P GO:0015123 acetate transmembrane transporter activity IBA
GO:0098734 macromolecule depalmitoylation AnnotationPropagation P GO:0008474 palmitoyl-(protein) hydrolase activity IBA
GO:0006913 nucleocytoplasmic transport AnnotationPropagation P GO:0017056 structural constituent of nuclear pore IBA
GO:0090150 establishment of protein localization to membrane AnnotationPropagation P GO:0032977 membrane insertase activity IBA
GO:0000316 sulfite transmembrane transport AnnotationPropagation P GO:0000319 sulfite transmembrane transporter activity IBA
GO:1902600 proton transmembrane transport AnnotationPropagation P GO:0005351 carbohydrate:proton symporter activity IBA
GO:0034219 carbohydrate transmembrane transport AnnotationPropagation P GO:0005351 carbohydrate:proton symporter activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation IBA
GO:0002943 tRNA dihydrouridine synthesis AnnotationPropagation P GO:0017150 tRNA dihydrouridine synthase activity IBA
GO:0006325 chromatin organization AnnotationPropagation P GO:0140566 histone reader activity IBA
GO:0019344 L-cysteine biosynthetic process AnnotationPropagation P GO:0004124 cysteine synthase activity IBA
GO:0006414 translational elongation AnnotationPropagation P GO:0003746 translation elongation factor activity IBA
GO:0006338 chromatin remodeling AnnotationPropagation P GO:0042054 histone methyltransferase activity IBA
GO:0005783 endoplasmic reticulum AnnotationPropagation C GO:0006621 protein retention in ER lumen IBA
GO:0045893 positive regulation of DNA-templated transcription AnnotationPropagation P GO:0003713 transcription coactivator activity IBA
GO:0006913 nucleocytoplasmic transport AnnotationPropagation P GO:0017056 structural constituent of nuclear pore IBA
GO:0045944 positive regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0120009 intermembrane lipid transfer AnnotationPropagation P GO:0008526 phosphatidylinositol transfer activity IBA
GO:0005829 cytosol AnnotationPropagation C GO:0042147 retrograde transport, endosome to Golgi IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0004932 mating-type factor pheromone receptor activity IBA
GO:0005737 cytoplasm AnnotationPropagation C GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport IBA
GO:0005829 cytosol AnnotationPropagation C GO:0042147 retrograde transport, endosome to Golgi IBA
GO:0006413 translational initiation AnnotationPropagation P GO:0003743 translation initiation factor activity IBA
GO:0005829 cytosol AnnotationPropagation C GO:0042147 retrograde transport, endosome to Golgi IBA
GO:0140331 aminophospholipid translocation AnnotationPropagation P GO:0015247 aminophospholipid flippase activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0034982 mitochondrial protein processing IBA
GO:0003333 amino acid transmembrane transport AnnotationPropagation P GO:0015171 amino acid transmembrane transporter activity IBA
GO:1903830 magnesium ion transmembrane transport AnnotationPropagation P GO:0015095 magnesium ion transmembrane transporter activity IBA
GO:0006761 dihydrofolate biosynthetic process AnnotationPropagation P GO:0008841 dihydrofolate synthase activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0007007 inner mitochondrial membrane organization IBA
GO:0005737 cytoplasm AnnotationPropagation C GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:1990569 UDP-N-acetylglucosamine transmembrane transport AnnotationPropagation P GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0032981 mitochondrial respiratory chain complex I assembly IBA
GO:0006633 fatty acid biosynthetic process AnnotationPropagation P GO:0000036 acyl carrier activity IBA
GO:0061025 membrane fusion AnnotationPropagation P GO:0005484 SNAP receptor activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0019344 L-cysteine biosynthetic process AnnotationPropagation P GO:0004124 cysteine synthase activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0006338 chromatin remodeling AnnotationPropagation P GO:0046969 histone H3K9 deacetylase activity, NAD-dependent IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0070588 calcium ion transmembrane transport AnnotationPropagation P GO:0005388 P-type calcium transporter activity IBA
GO:1903826 L-arginine transmembrane transport AnnotationPropagation P GO:0061459 L-arginine transmembrane transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0033617 mitochondrial respiratory chain complex IV assembly IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0042407 cristae formation IBA
GO:0098655 monoatomic cation transmembrane transport AnnotationPropagation P GO:0008324 monoatomic cation transmembrane transporter activity IBA
GO:0052699 ergothioneine biosynthetic process AnnotationPropagation P GO:1990411 hercynylcysteine sulfoxide lyase activity (ergothioneine-forming) IBA
GO:0035672 oligopeptide transmembrane transport AnnotationPropagation P GO:0035673 oligopeptide transmembrane transporter activity IBA
GO:0003333 amino acid transmembrane transport AnnotationPropagation P GO:0015185 gamma-aminobutyric acid transmembrane transporter activity IBA
GO:0015812 gamma-aminobutyric acid transport AnnotationPropagation P GO:0015185 gamma-aminobutyric acid transmembrane transporter activity IBA
GO:1905039 carboxylic acid transmembrane transport AnnotationPropagation P GO:0015185 gamma-aminobutyric acid transmembrane transporter activity IBA
GO:0005737 cytoplasm AnnotationPropagation C GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:1905039 carboxylic acid transmembrane transport AnnotationPropagation P GO:0046943 carboxylic acid transmembrane transporter activity IBA
GO:0006338 chromatin remodeling AnnotationPropagation P GO:0004407 histone deacetylase activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0035434 copper ion transmembrane transport AnnotationPropagation P GO:0005375 copper ion transmembrane transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0034551 mitochondrial respiratory chain complex III assembly IBA
GO:1990822 basic amino acid transmembrane transport AnnotationPropagation P GO:0015174 basic amino acid transmembrane transporter activity IBA
GO:0034755 iron ion transmembrane transport AnnotationPropagation P GO:0015093 ferrous iron transmembrane transporter activity IBA
GO:1902600 proton transmembrane transport AnnotationPropagation P GO:0005351 carbohydrate:proton symporter activity IBA
GO:0034219 carbohydrate transmembrane transport AnnotationPropagation P GO:0005351 carbohydrate:proton symporter activity IBA
GO:0098655 monoatomic cation transmembrane transport AnnotationPropagation P GO:0005227 calcium-activated cation channel activity IBA
GO:1990822 basic amino acid transmembrane transport AnnotationPropagation P GO:0015174 basic amino acid transmembrane transporter activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:1903352 L-ornithine transmembrane transport AnnotationPropagation P GO:0000064 L-ornithine transmembrane transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0006264 mitochondrial DNA replication IBA
GO:0071805 potassium ion transmembrane transport AnnotationPropagation P GO:0140107 high-affinity potassium ion transmembrane transporter activity IBA
GO:1901679 nucleotide transmembrane transport AnnotationPropagation P GO:0005471 ATP:ADP antiporter activity IBA
GO:0015867 ATP transport AnnotationPropagation P GO:0005471 ATP:ADP antiporter activity IBA
GO:0015866 ADP transport AnnotationPropagation P GO:0005471 ATP:ADP antiporter activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:1902476 chloride transmembrane transport AnnotationPropagation P GO:0005247 voltage-gated chloride channel activity IBA
GO:0002943 tRNA dihydrouridine synthesis AnnotationPropagation P GO:0017150 tRNA dihydrouridine synthase activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0045944 positive regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific IBA
GO:0071934 thiamine transmembrane transport AnnotationPropagation P GO:0015234 thiamine transmembrane transporter activity IBA
GO:0003333 amino acid transmembrane transport AnnotationPropagation P GO:0015171 amino acid transmembrane transporter activity IBA
GO:0005737 cytoplasm AnnotationPropagation C GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0035349 coenzyme A transmembrane transport AnnotationPropagation P GO:0015228 coenzyme A transmembrane transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0034982 mitochondrial protein processing IBA
GO:0005737 cytoplasm AnnotationPropagation C GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport IBA
GO:0005737 cytoplasm AnnotationPropagation C GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport IBA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0004930 G protein-coupled receptor activity IBA
GO:0001676 long-chain fatty acid metabolic process AnnotationPropagation P GO:0004467 long-chain fatty acid-CoA ligase activity IBA
GO:0045892 negative regulation of DNA-templated transcription AnnotationPropagation P GO:0003714 transcription corepressor activity IBA
GO:0005737 cytoplasm AnnotationPropagation C GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport IBA
GO:0005737 cytoplasm AnnotationPropagation C GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport IBA
GO:1990822 basic amino acid transmembrane transport AnnotationPropagation P GO:0015174 basic amino acid transmembrane transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0033617 mitochondrial respiratory chain complex IV assembly IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0034551 mitochondrial respiratory chain complex III assembly IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0032543 mitochondrial translation IBA
GO:0051168 nuclear export AnnotationPropagation P GO:0005049 nuclear export signal receptor activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0016192 vesicle-mediated transport AnnotationPropagation P GO:0140312 cargo adaptor activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0045039 protein insertion into mitochondrial inner membrane IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0042626 ATPase-coupled transmembrane transporter activity IBA
GO:0035434 copper ion transmembrane transport AnnotationPropagation P GO:0005375 copper ion transmembrane transporter activity IBA
GO:1902475 L-alpha-amino acid transmembrane transport AnnotationPropagation P GO:0015179 L-amino acid transmembrane transporter activity IBA
GO:0005737 cytoplasm AnnotationPropagation C GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport IBA
GO:0006338 chromatin remodeling AnnotationPropagation P GO:0032454 histone H3K9 demethylase activity IBA
GO:0120009 intermembrane lipid transfer AnnotationPropagation P GO:0008526 phosphatidylinositol transfer activity IBA
GO:0019430 removal of superoxide radicals AnnotationPropagation P GO:0004784 superoxide dismutase activity IBA
GO:1901679 nucleotide transmembrane transport AnnotationPropagation P GO:0005347 ATP transmembrane transporter activity IBA
GO:0015867 ATP transport AnnotationPropagation P GO:0005347 ATP transmembrane transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0070150 mitochondrial glycyl-tRNA aminoacylation IBA
GO:1990822 basic amino acid transmembrane transport AnnotationPropagation P GO:0015174 basic amino acid transmembrane transporter activity IBA
GO:0005634 nucleus AnnotationPropagation C GO:0071028 nuclear mRNA surveillance IBA
GO:0003333 amino acid transmembrane transport AnnotationPropagation P GO:0015171 amino acid transmembrane transporter activity IBA
GO:0006413 translational initiation AnnotationPropagation P GO:0003743 translation initiation factor activity IBA
GO:0005794 Golgi apparatus AnnotationPropagation C GO:0032468 Golgi calcium ion homeostasis IBA
GO:0006355 regulation of DNA-templated transcription AnnotationPropagation P GO:0003700 DNA-binding transcription factor activity IBA
GO:0003333 amino acid transmembrane transport AnnotationPropagation P GO:0015185 gamma-aminobutyric acid transmembrane transporter activity IBA
GO:0015812 gamma-aminobutyric acid transport AnnotationPropagation P GO:0015185 gamma-aminobutyric acid transmembrane transporter activity IBA
GO:1905039 carboxylic acid transmembrane transport AnnotationPropagation P GO:0015185 gamma-aminobutyric acid transmembrane transporter activity IBA
GO:0006338 chromatin remodeling AnnotationPropagation P GO:0032041 histone H3K14 deacetylase activity, NAD-dependent IBA
GO:0035433 acetate transmembrane transport AnnotationPropagation P GO:0015123 acetate transmembrane transporter activity IBA
GO:0045893 positive regulation of DNA-templated transcription AnnotationPropagation P GO:0003713 transcription coactivator activity IBA
GO:1990822 basic amino acid transmembrane transport AnnotationPropagation P GO:0015174 basic amino acid transmembrane transporter activity IBA
GO:0006414 translational elongation AnnotationPropagation P GO:0003746 translation elongation factor activity IBA
GO:0051726 regulation of cell cycle AnnotationPropagation P GO:0004693 cyclin-dependent protein serine/threonine kinase activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0032979 protein insertion into mitochondrial inner membrane from matrix IBA
GO:0090150 establishment of protein localization to membrane AnnotationPropagation P GO:0032977 membrane insertase activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0000957 mitochondrial RNA catabolic process IBA
GO:0106004 tRNA (guanine-N7)-methylation AnnotationPropagation P GO:0008176 tRNA (guanine(46)-N7)-methyltransferase activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0035350 FAD transmembrane transport AnnotationPropagation P GO:0015230 FAD transmembrane transporter activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0034553 mitochondrial respiratory chain complex II assembly IBA
GO:1905039 carboxylic acid transmembrane transport AnnotationPropagation P GO:0046943 carboxylic acid transmembrane transporter activity IBA
GO:0006338 chromatin remodeling AnnotationPropagation P GO:0140750 nucleosome array spacer activity IBA
GO:1990822 basic amino acid transmembrane transport AnnotationPropagation P GO:0015174 basic amino acid transmembrane transporter activity IBA
GO:0006913 nucleocytoplasmic transport AnnotationPropagation P GO:0017056 structural constituent of nuclear pore IBA
GO:0071918 urea transmembrane transport AnnotationPropagation P GO:0015204 urea transmembrane transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0045040 protein insertion into mitochondrial outer membrane IBA
GO:0015718 monocarboxylic acid transport AnnotationPropagation P GO:1901604 dethiobiotin transmembrane transporter activity IBA
GO:1905039 carboxylic acid transmembrane transport AnnotationPropagation P GO:1901604 dethiobiotin transmembrane transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0007007 inner mitochondrial membrane organization IBA
GO:0098869 cellular oxidant detoxification AnnotationPropagation P GO:0004791 thioredoxin-disulfide reductase (NADPH) activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:1902600 proton transmembrane transport AnnotationPropagation P GO:0005351 carbohydrate:proton symporter activity IBA
GO:0034219 carbohydrate transmembrane transport AnnotationPropagation P GO:0005351 carbohydrate:proton symporter activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0015205 nucleobase transmembrane transporter activity IBA
GO:0015851 nucleobase transport AnnotationPropagation P GO:0015205 nucleobase transmembrane transporter activity IBA
GO:0005634 nucleus AnnotationPropagation C GO:0033260 nuclear DNA replication IBA
GO:0071421 manganese ion transmembrane transport AnnotationPropagation P GO:0005384 manganese ion transmembrane transporter activity IBA
GO:0006413 translational initiation AnnotationPropagation P GO:0003743 translation initiation factor activity IBA
GO:0006913 nucleocytoplasmic transport AnnotationPropagation P GO:0017056 structural constituent of nuclear pore IBA
GO:0005829 cytosol AnnotationPropagation C GO:0042147 retrograde transport, endosome to Golgi IBA
GO:0005829 cytosol AnnotationPropagation C GO:0006895 Golgi to endosome transport IBA
GO:1990822 basic amino acid transmembrane transport AnnotationPropagation P GO:0015174 basic amino acid transmembrane transporter activity IBA
GO:0034755 iron ion transmembrane transport AnnotationPropagation P GO:0005381 iron ion transmembrane transporter activity IBA
GO:0098655 monoatomic cation transmembrane transport AnnotationPropagation P GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0033617 mitochondrial respiratory chain complex IV assembly IBA
GO:0006325 chromatin organization AnnotationPropagation P GO:0140463 chromatin-protein adaptor activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0000781 chromosome, telomeric region AnnotationPropagation C GO:0031509 subtelomeric heterochromatin formation IBA
GO:0005829 cytosol AnnotationPropagation C GO:0006895 Golgi to endosome transport IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0070124 mitochondrial translational initiation IBA

Predictions (experimental)